| | R esearch | | Drug Discovery Collaborations between Academia and the Pharmaceutical Industry: Cult Aarkstore.com The pharmaceutical and biopharmaceutical industries are engaged in a businessenvironment which is witnessing a dramatic escalation of R&D costs, key patent expiries, and sustained high attrition rates for new molecules in development. In response, pharmaceutical companies have recognized the need to expand the range of creative stimuli for their research processesin order to reinvigorate their drug discovery pipelines. Consequently the industry has sought to develop external collaborations not only with other companies but also more frequently with academia, to obtain accessto new technologies to enhance their drug discovery capabilities and to in-license candidates for further development. Indeed, collaboration is becoming an essential component of today’s drug discovery efforts and it is commonly undertaken with multiple partners through an often iterative, continuous, and long lasting process, which adds to the complexity of efficiently managing both the collaboration itself and the data generated. This report explores the opportunities and challenges that are presented by collaboration with university researchers as well as identifying the key inputs from both the industrial and academic partners. The different organizational cultures and structures are examined along with consideration of the goals for each institution and the issuesthese create. The report discussesthe various types of agreement which can be used, highlights legislation of importance to the appropriate protection of intellectual property, and presents casestudies of notable collaborations In addition the report offers thoughts on the future for collaborative agreements and the benefits they will bring to both parties.
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