How does tadalafil powder work?

Okay, now that we know a little more about tadalafil, why don’t we try to understand what its effect is due to? In the paragraphs above we said that Tadalafil is a PDE5 inhibitor – but what exactly does that mean? Let’s take a closer look at the chemistry that stands behind the power of this medication.

PDE5 is an enzyme found in most men suffering from erectile dysfunction. It suppresses another very important substance – cGMP, or cyclic guanosine monophosphate, which is a crucial component in the process of healthy erection. Thanks to cGMP the signals from the nerve endings in your pelvic region trigger the release of nitric oxide, which, consequently, relaxes the smooth muscles lining the blood vessels in your pelvis. As the result, more blood can flow through them, filling the cavernous structures in the body of your penis, making it become hard and engorged. When there’s too much PDE5 and not enough cGMP, your body simply cannot decipher the signals coming from your nerve endings, which results in complete or partial inability to obtain an erection.