Can urolithin A powder can use in bodybuilding?

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www.aasraw.com King@aasraw.com WhatProductsCanHelpUsToBoostMuscleFast? Therearemanywaystoimproveyourmusclegrowthandseesignificantchangesinyour physique,themostimportantofwhichistoconsumeenoughproteins.Proteinconsumption witheverymealcanbenefityourmusclegrowth,astheaminoacidsfromtheseproteinshelp repairmuscledamageandreplenishtheproteinstoresinthemuscles,afteranextensive workoutCarbsshouldbeavoidedgenerally,exceptafteraworkoutwhenmusclegrowthisthe goal. Anotherquickwaytoboostmusclegrowthistheuseofsteroids.Theyoftengetabad reputationassomeofthesteroidtypesarebannedforusebyanybodybuilderorathleteby theassociatedauthorities.However,therearemultipleothertypesthataresafeandlegalto use,whichhavealsobeenproventobebeneficialthroughmultiplepiecesofscientificstudies. Steroidscanbeappliedtopically,ortakenintheformofapilloraninjection,directlyintothe muscle.Thepurposeofthesesteroidsistonotonlyincreasethesizeofthemuscle,hence resultinginsignificantmusclegrowthbutalsotoincreasethestrengthofthemuscles. Bodybuilderswhousesteroidsreportanimprovementinstaminaandenduranceinthegym, whichisdefinitelyaplusinthefavorofsteroids.

www.aasraw.com King@aasraw.com WhatisUrolithinA(UA)? UrolithinAisanorganiccompoundthatissynthesizedfromellagitanninsbythemicrobiotain thegut.Urolithinsarepolycyclicaromaticcompoundsthataremetabolitesformedfrom precursorssuchasellagicacidandellagitannins,whicharefoundinnaturalfruitssuchas pomegranate. PomegranatepeelisrichinUrolithinBwhileUrolithinAhasnospecificdietarysource.Instead, itisformedbytheconversionofthetanninsfoundinthefruitsbythegutflora.The compositionofdietarysourcesofellagitanninsismentionedinthetablebelow.Thesedietary

www.aasraw.com King@aasraw.com sourcesactasindirectsourcesofUrolithinA,inthepresenceofhealthygutmicrobiotawhich arecapableofperformingtheconversionprocess Dietarysource EllagicAcid Fruits Blackberries 150 Blackraspberries 90 Boysenberries 70 Cloudberries 3151 Pomegranate 269.9 Raspberries 270 Rosehip 1096 Strawberries 77.6 Strawberryjam 245 Yellowraspberries 1900 Nuts(mg/g) Pecans 33 Walnuts 59 Beverages(mg/L) Pomegranatejuice 811.1 Cognac 3155 Oakagedredwine 33 Whiskey 1.2 Seeds(mg/g) Blackraspberries 67 Redraspberries 8.7 Boysenberries 30 Mango 1.2 HowUrolithin-AWorkOnBoostingMuscle?

UrolithinAhastakenoversteroids’placeinthemarketastheyaresafeandpotentmuscle boostersUrolithinAsupplierspromotetheuseofthissupplementbecauseofthemany benefitsoftheproduct,themostimportantofwhichismusclegrowthMusclestrength, growth,andendurancearehighlydependentonthemitochondrialfunctioninthecells. Mitochondriaarethepowerhouseofthecell,andtheyareresponsiblefortheproductionof ATP,whichistheenergycurrencyofthebody.

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ImprovedMuscleStrengthintheElderly Asoneages,musclestrength,size,andendurancedecreasesignificantlyThatcanbeblamed fordecreasedfunctioningofmitochondriaandtheoverallaccumulationoffailingmitochondria. Thisreductioninmitophagyplaysanimportantroleinhinderingtheelderlyfromperforming dailylifeactivitiesandtasks.ThesolutiontothisproblemhasbeenfoundtobeUrolithinA powder. Therewasanotherstudythatwasperformedwiththepurposeofdeterminingtheeffectof UrolithinAonmusclestrengthandenduranceintheelderly,whoexperienceadecreasein mitochondrialactivitywithage. Accordingtotheresearchersperformingtheclinicaltrial,therewasaresolutionoffailing mitophagyamongsttheparticipantsofthestudy,indicatingtheclearanceofdysfunctional mitochondriaandimprovementofmitochondrialhealthoverall.Comparedtothegroupthat

King@aasraw.com receivedplacebo,theparticipantsgiventheUrolithinAsupplementreportedsignificant improvementofenduranceandstrengthofmusclesinlegsandarmsTherewasreduced fatigueandanoverallimprovementintheabilitytoperformdailyfunctions ResearchersalsonotedthattheUrolithinAsupplementcouldbeanalternativemethodof improvingmusclestrengthandstaminaamongstelderlyindividualswhocannotperform exerciseduetophysicalormentalhealthissues.AccordingtotheCenterforDiseaseControl andPreventionorCDC,dailyexercisecanhelpcombatmobilityissues,fallrisks,andother movementdisordersintheelderly.However,whenthisisn’tpossible,takingUrolithinA supplementscanbringmitophagytonormallevels,hence,havingthesameeffectasexercise. ManagementofDuchenneMuscularDystrophy However,withdegenerativemusculardiseasessuchasDuchenneMuscularDystrophyorDMD, themitochondrialcontentofthecellsisdefectiveandthemitochondriapresentdonot functionproperly.Moreover,inDMD,mitophagyissignificantlyreduced,whichisaprocess throughwhichourbodiesremovedysfunctioningmitochondriaandrecyclethecontentto meetthehighenergydemandsofthebody.

OneoftheresearchesconductedtostudytheeffectsofUrolithinApowderonmusclegrowth focusedontheeffecttheformerhasonmitophagy.Researchersfoundthatsupplementation withUrolithinAsignificantlyimprovedthemitophagylevels,returningthembacktonormalin

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www.aasraw.com King@aasraw.com musculardystrophypatientsTheseresultswereseenonbothanimalmodelsandhuman subjects,indicatingthatUrolithinAcanbesuccessfullyusedtomanagethesymptomsof musculardystrophiesMoreover,researchersrecordedawhopping40percentincreasein survivalratesofanimalmodelsgiventheUrolithinAsupplementcomparedtothosewho didn’treceivethesupplement.Thegripstrengthandrunningstrengthincreasedby31percent and45percent,respectively,intheseanimalmodels.

AnotherimportantbenefitofUrolithinAsupplementationthatwasnoticedduringthisstudy wasthatitreducedfibrosisorscarringoftheheartanddiaphragmofthemicewithDMD.This isanimportantcomplicationofDMDthatcannowbemanagedthroughUrolithinApowder.

www.aasraw.com King@aasraw.com References: [1]GuadaM,GanugulaR,VadhanamM,RaviKumarMNV.UrolithinAMitigatesCisplatinInducedNephrotoxicityby InhibitingRenalInflammationandApoptosisinanExperimentalRatModelJPharmacolExpTher2017;363(1):5865 doi:10.1124/jpet.117.242420. [2]“FDAGRASnoticeGRNNo791:urolithinA”USFoodandDrugAdministration20December2018Retrieved25 August2020 [3]LandeteJM(2011)“Ellagitannins,ellagicacidandtheirderivedmetabolites:Areviewaboutsource,metabolism, functionsandhealth”FoodResearchInternational44(5):11501160doi:101016/jfoodres201104027

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