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Everything You Need Know About Spermidine Powder
1. Spermidine Powder Description Spermidine powder is a fascinating compound and it is precursor of spermine. many foods contain spermidine, such as mushrooms, soybeans, nuts, and especially wheat germ.Spermidine is found in all plants and animals and in nearly every cell of your body. In our bodies, it can come from ingested food—synthesized in the gut microbiome or synthesized in cells.Spermidine powder plays an essential role in organisms, like humans and even plants. One of spermidine's biggest and most profound functions, from which other functions stem from, is the ability to counteract aging and promote autophagy.
2. Spermidine Mechanism of Action Spermidine is an aliphatic polyamine. Spermidine synthase (SPDS) catalyzes its formation from putrescine. It is the precursor of other polyamines, such as spermine and its structural isomer, hot spermine. Spermidine is a longevity agent in mammals due to various mechanisms of action, and these mechanisms are just beginning to be understood. Autophagy is the main mechanism at the molecular level, but evidence for other mechanisms has been found, including reduced inflammation, lipid metabolism, and regulation of cell growth, proliferation, and death.
3. Benifits of Spermidine Powder Spermidine is essential in the cell renewal process. As old cells die, other cells cannibalize them and use molecules to build new cells. As we age, the natural level of spermidine in our body will decrease, thereby reducing the ability of cells to renew and repair themselves. 1
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Spermidine has also been shown to reduce the risk of certain forms of cancer, and if taken long-term enough, it can prolong life. And may improve vaccine protection for the elderly. And spermidine plays a key role in maintaining cell membrane potential and controlling intracellular pH and volume. Studies have also shown that it can reduce the risk of cardiovascular disease and improve cognition. Spermidine has a neuroprotective effect on neuronal damage caused by inflammation, ischemia and oxidative stress.
4. Effects of Spermidine Powder Due to various mechanisms of action, spermidine is a longevity agent for mammals, including reduced inflammation, lipid metabolism, and regulation of cell growth, proliferation, and death. Spermidine can prevent liver fibrosis and hepatocellular carcinoma which are one of the most common causes of liver cancer. It is commonly used in supplements which, when taken, regularly, can have a significant impact on longevity.
5. Spermidine trihydrochloride Powder Description Spermidine trihydrochloride powder is also a polyamine that inhibits neuronal nitric oxide synthase (nNOS) and binds and precipitates DNA. It may be used to purify DNA binding proteins. Additionally, spermidine stimulates T4 polynucleotide kinase activity. It is involved in growth, development, and the stress response in plants.
6. Spermidine trihydrochloride Mechanism of Action Spermidine trihydrochloride is a natural polyamine produced from putrescine and decarboxylated S-adenosylmethionine (dcSAM) by spermidine synthase, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate 2
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(NMDA). Binds to the polyamine modulatory site of the NMDA receptor and has been described as an agonist based on its ability to enhance the binding of [3H]-MK801.
7. Spermidine trihydrochloride Powder Application Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements. Spermidine hydrochloride is found widely in nature and essential for tissue growth; It often used as a tool in biochemical research;Spermidine hydrochloride is a polyamine compound, C7H22Cl3N3, found in ribosomes and living tissues and having various metabolic functions within organisms.
8. Effects of Spermidine trihydrochloride Powder Spermidine trihydrochloride powder is Inhibits neuronal nitric oxide synthase (nNOS). It binds and precipitates DNA; Spermidine trihydrochloride powder may be used for purification of DNA binding proteine and timulates T4 polynucleotide kinase activity.
9. Where to Buy Bulk Spermidine Powder? AASraw is a manufacturer and supplier of bulk spermidine powder for sale. If you want to buy spermidine powder in large quantities, please send an inquiry to us directly.The top quality speridine powder with the most compeptitive price will be provided by us!
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Spermidine-98% Pure CAS: 124-20-9 Spermidine powder is a polyamine derived from putrescine that is involved in many biological processes, including the regulation of membrane potential, the inhibition of nitric oxide synthase (NOS) and the induction of autophagy. It is found in almost all tissues in association with nucleic acids. It is cationic at all pH values and is believed to help stabilize certain membrane and nucleic acid structures.
Product Name CAS Number Molecular Formula Formula Weight Synonyms
Spermidine 124-20-9 C7H19N3
145.25 Spermidine, 124-20-9, 1,5,10-Triazadecane, 4-Azaoctamethylenediamine, Spermidin, Appearance White powder Storage and RT Handling
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Spermidine trihydrochloride CAS: 334-50-9 Spermidine trihydrochloride powder is a natural polyamine produced from putrescine and decarboxylated S-adenosylmethionine (dcSAM) by spermidine synthase, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA). Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements. Spermidine hydrochloride is found widely in nature and essential for tissue growth; Used as a tool in biochemical research; "Spermidine hydrochloride is a polyamine compound, C7H22Cl3N3, found in ribosomes and living tissues and having various metabolic functions within organisms. Product Name CAS Number Molecular Formula Formula Weight Synonyms
Appearance Storage Handling
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Spermidine trihydrochloride 334-50-9 C7H22Cl3N3 254.6 N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride;1,8-Diamino-4-azaoctane trihydrochloride;1,5,10-Triazadecane trihydrochloride;S permidine.3HCl White powder and Dry, dark and 0 - 4 C for short term, or -20 C for long term.
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Wheat Germ Extrac Powder(1%) CAS：124-20-91 Wheat germ extract powder is a concentrated extract of wheat germ derived from the germ (endosperm, or seed) of the wheat plants. It has rich in spermidine which bring much benefits on our body.Wheat germ extract powder can resistant to eht sterile,anti-aging;It promote human metabolism,enhance physical strength and memory;It can Lower cholesterol,preventing atherosclerosis;It can improve blood circulation and strengthen the immune system. For now, there are many spermidine supplements in market and most of sources are wheat germ extract powder. Welcome to buy bulk wheat germ extract powder from us! Product Name CAS Number Molecular Formula Formula Weight Synonyms
Wheat Germ Extract Powder-1% 124-20-9 C7H19N3
145.25 Spermidine-rich wheat germ extract, SPERMIDINELIFE, 1,4-Butanediamine,N1-(3-aminopropyl) , N-(3-Aminopropyl)-1,4-diaminobutane 1,8-Diamino-4-azaoctane; Fermented wheat germ extract; fermented wheat germ powder Appearance White to yellowish powder Storage and RT Handling
【Reference】 [1] American Heritage Dictionary Retrieved 2014-11-18. [2] Minois, Nadège (28 January 2014). "Molecular Basis of the "Anti-Aging" Effect of Spermidine and Other Natural Polyamines – A Mini-Review". Gerontology. 60 (4): 319–326. doi:10.1159/000356748. PMID 24481223. [3] Madeo F, Eisenberg T, Pietrocola F, Kroemer G (2018). "Spermidine in health and disease". Science. 359 (6374): eaan2788. doi:10.1126/science.aan2788. PMID 29371440. 6
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[4] Ramot, Yuval; Tiede, Stephan; Bíró, Tamás; Abu Bakar, Mohd Hilmi; Sugawara, Koji; Philpott, Michael P.; Harrison, Wesley; Pietilä, Marko; Paus, Ralf (27 July 2011). "Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions". PLOS ONE. 6 (7): e22564. doi:10.1371/journal.pone.0022564. ISSN 1932-6203. PMC 3144892. PMID 21818338. [5] Munir et al (1993) Polyamines modulate the neurotoxic effects of NMDA in vivo. Brain Res. 616 163 PMID: 8358608 [6] Williams et al (1989) Effects of polyamines on the binding of [3H]-MK801 to the N-MthD.-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site. Mol.Pharmacol. 36 375 PMID: 2554112
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