AASrawBiochemicalTechnologyCo.,ltd www.aasraw.com king@aasraw.com Whatbenefitscanwegetfrompregabalinpowder? PregabalinPowderReviews Pregabalinpowderiswhitepowderwhchusedasanantiepilepticdrug,alsocalledan anticonvulsant.Itworksbyslowingdownimpulsesinthebrainthatcauseseizures. Pregabalinpowderalsoaffectschemicalsinthebrainthatsendpainsignalsacrossthe nervoussystem. Pregabalinpowderisusedtotreatpaincausedbyfibromyalgia,ornervepaininpeoplewith
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Pregabalinpowderisalsousedwithothermedicationstotreatpartialonsetseizuresin adultsandchildrenwhoareatleast1monthold.Pregabalinrawpowdermayalsobeused forpurposesnotlistedinthismedicationguide. PregabalinMechanismofAction
Pregabalinisananticonvulsantdrugusedtotreatneuropathicpainconditionsand fibromyalgia,andforthetreatmentofpartialonsetseizuresincombinationwithother anticonvulsants. Althoughthemechanismofactionhasnotbeenfullyelucidated,studiesinvolving structurallyrelateddrugssuggestthatpresynapticbindingofpregabalintovoltagegated calciumchannelsiskeytotheantiseizureandantinociceptiveeffectsobservedinanimal models. Bybindingpresynapticallytothealpha2-deltasubunitofvoltage-gatedcalciumchannelsin thecentralnervoussystem,pregabalinmodulatesthereleaseofseveralexcitatory neurotransmittersincludingglutamate,substanceP,norepinephrine,andcalcitoningene relatedpeptide.Inaddition,pregabalinpreventsthealpha2deltasubunitfrombeing
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benzodiazepinereceptors.
AASrawBiochemicalTechnologyCo.,ltd www.aasraw.com king@aasraw.com traffickedfromthedorsalrootgangliatothespinaldorsalhorn,whichmayalsocontribute tothemechanismofaction.Althoughpregabalinisastructuralderivativeoftheinhibitory neurotransmittergammaaminobutyricacid(GABA),itdoesnotbinddirectlytoGABAor
Uses/ApplicationofPregabalin ❶Pharmacologicalefficacy:Pregabalinisanovelγaminobutyricacid(GABA)receptor agonist,canblockthevoltagedependentcalciumchannelstoreduceneurotransmitter release. ❷Themainclinicalforthetreatmentofperipheralneuropathicpainaswellaspartof adjuvanttreatmentoffocalseizures. ❸Treatmentofepilepsyindevelopingthemostpromisingdruginadrugtreatmentbetter andmoreconvenientadministration.Itcanalsobeusedtotreatpainandanxiety. SideEffectsofPregabalin Likemostmedications,LyricacancausemildorserioussideeffectsThisisnotacomplete listofsideeffectsandothersmayoccurAhealthcareprovidercanadviseyouonside effects.Ifyouexperienceothereffects,contactyourpharmacistorahealthcareprovider.
AASrawBiochemicalTechnologyCo.,ltd www.aasraw.com king@aasraw.com CommonSideEffects Youmayexperiencesideeffectswhiletakingpregabalin.Thecommonsideeffectsof pregabalininclude: ▪dizziness ▪drowsiness ▪confusion ▪blurredvision ▪tremor ▪unsteadinesswhenwalking ▪weightgain ▪constipation ▪drymouth. SevereSideEffects Callyourproviderrightawayifyouhaveserioussideeffects.Call911ifyoursymptomsfeel lifethreateningorifyouthinkyouhaveamedicalemergency.Serioussideeffectsandtheir symptomscanincludethefollowing:
AASrawBiochemicalTechnologyCo.,ltd www.aasraw.com king@aasraw.com ▪Suicidalthoughtsorsuicideattempts:Symptomsmayincludesuicideattempts,newor worseninganxietyordepression,troublesleeping,agitation,actingondangerousimpulses, andunusualchangesinmoodorbehavior. ▪Severeallergicreactions:Symptomsmayincludetroublebreathing,hives,andswellingof thetongue,lips,mouth,orthroat. ▪Heartproblems ▪Seriousbreathingproblems Somesideeffectsmaygetbetterovertime,whileotherssuchasdizzinessanddrowsiness maylastaslongasyoutakethemedicine. PregabalinStorage Peopleshouldstorethismedicationatacontrolledroomtemperature,about68degreesto 77degreesFahrenheit. Iftraveling,alwayscarryyourmedicationwithyouandkeeptheoriginal prescriptionlabeledbottleorboxinyourcarryonbag.Don’tleavethismedicationinyour car,especiallyinverycoldorhottemperatures. GuidetoBuyPregabalinPowderfromAASrawstepbystep ♦VisitAASwebsite,choosethepregabalinpowderyouwant,andleaveyourcontactand
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neuropathicpain:evidencebasedrecommendations.Pain2007;132:23751.
neuropathicpain.NeuropsychiatricDiseaseandTreatment2007;3:88591.
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Reference [1]DworkinRH,O’ConnorAB,BackonjaM,etal.Pharmacologicmanagementof
[2]FinnerupNB,JensenTS.Clinicaluseofpregabalininthemanagementofcentral
[3]KalsoE,AldingtonDJ,MooreRA.Drugsforneuropathicpain.BMJ2013;347:f7339. [4]Mannix,Liam(December18,2018).“Thispopulardrugislinkedtoaddictionandsuicide.
Whydodoctorskeepprescribingit?”.TheCanberraTimes.Archivedfromtheoriginalon December18,2018.RetrievedDecember18,2018. [5]Wheless,JamesW.;Willmore,James;Brumback,RogerA.(2009).AdvancedTherapyin Epilepsy.PMPHUSA.p.302.ISBN9781607950042.
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