Cancer Metabolism Based Therapeutics Market GLOBAL INDUSTRY INSIGHTS, TRENDS, OUTLOOK, AND OPPORTUNITY ANALYSIS, 2018-2026
REPORT DESCRIPTION Cancer Metabolism Based Therapeutics Market – Overview According to the study published in the Journal of Cancer Biology and Therapy, 2013, the controversial discovery of the 20th century by Otto Warburg led to study of metabolic activity in cancerous tissue, which increases the amount of production of lactate from glucose by tenfold under aerobic condition. This has revealed that heterogeneity is developed at cellular level leading to proliferation of cancerous cells due to increased metabolism rate. Cancer metabolism is based on the principle of cancer cells, which alter the metabolism of glucose and glutamine for the synthesis of lipids, nucleotides, fatty acids, and proteins that helps to proliferate cancer cells. It results in inhibition of various metabolic pathways, such as the citric acid cycle, glucose, mitochondrial respiration, and glutamine utilization. Limited options of cancer metabolism targeting therapies are expected provide potential opportunities for development of novel cancer metabolism-based therapeutics in the near future. Rafael pharmaceuticals, introduced a breakthrough drug, CPI-613 in 2017, which is an anti-cancer compound Altered Energy Metabolic Directed (AEMD) drug specifically designed to target the mitochondrial tricarboxylic acid (TCA) cycle in cancer metabolism. CPI-613 is being evaluated in clinical trial phase II. The Food and Drug Administration (FDA) designated CPI-613 as an orphan drug for the treatment of pancreatic cancer, acute myeloid leukemia (AML), and Myelodysplastic syndromes (MDS).
REPORT DESCRIPTION Cancer Metabolism Based Therapeutics Market Taxonomy: By Drug – CPI-613 Enasidenib By Indication – Acute Myeloid Leukemia (AML) Myelodysplastic Syndromes (MDS) Metastatic Renal Cell Carcinoma Melanoma Others Get Request a Sample Copy @ https://www.coherentmarketinsights.com/insight/request-sample/961
REPORT DESCRIPTION Cancer Metabolism Based Therapeutics Market – Key Players Calithera Biosciences Celgene Corporation Agios Pharmaceutical Rafael pharmaceuticals 3-V Biosciences AstraZeneca According to the American Cancer Society (ACS), approximately 53,670 people are expected be diagnosed with pancreatic cancer and approximately 43,090 people are expected to die due to pancreatic cancer in the U.S in 2017. As per the ACS, pancreatic cancer accounts for around 3% of all cancers and around 7% of all cancer deaths in the U.S. Moreover, according to Cancer Research UK, approximately 3,072 new cases were diagnosed with acute myeloid leukemia (AML) and around 2,516 deaths were occurred in 2014.
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