Walter De Gruyter - New in Medicine May 2011

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APD Singapore Pte Ltd (Malaysia) De Gruyter May 2011 - New In Medicine

Hemolysis - An unresolved dispute in laboratory medicine By Lippi, Giuseppe / Cervellin, Gianfranco / Favaloro, Emmanuel / Plebani, Mario. Paperback | Euro [D] 49.95 ISBN 978-3-11-024613-1 Series: Patient Safety Also available as an eBook: ISBN 978-3-11-024614-8 | € 49.95 24 x 17 cm. Approx. v, 200 pages. 10 fig. 10 tables Languages: English Type of Publication: Specialist Text

About this Title   

Clinically relevant findings about hemolysis Indicates possible laboratory errors caused by hemolysis Management of hemolytic speciments

Defined as red blood cell break down and the release of hemoglobin and intracellular contents into the plasma, haemolysis can seriously impact patient care as well as the laboratory’s reputation through its affect on test results. Therefore, the European Preanalytical Scientific Committee, in collaboration with the International Federation of Clinical Chemistry Working Group on Patient Safety, have designed a questionnaire to collect data on prevalence and management of haemolytic specimens referred to the clinical laboratories for clinical chemistry testing. The new book will help identify the areas where haemolysis occurs most frequently, which can, in turn, guide further analysis about why it is occurring. Once these elements are known, practices and procedures can be implemented to dramatically reduce haemolysis and avoid erroneous laboratory results affecting patient care and increasing laboratory costs.

Subjects Medicine > Medicine, General Medicine > Clinical Medicine > Clinical Medicine, General

Keywords Hemolysis; Laboratory Medicine; Emergency Medical Aid

Readership Laboratory Professional

Please Send Your Orders to:

APD Singapore Pte Ltd (Malaysia Office) No. 22, 24 & 26 Jalan SS3/41, 47300, Petaling Jaya Tel: 603 78776063 / 5224 | Fax: 603 7877 3414 | Email: customersvc@apdkl.com


APD Singapore Pte Ltd (Malaysia) De Gruyter May 2011 - New In Medicine

Effects of Herbal Supplements on Clinical Laboratory Test Results By Dasgupta, Amitava Paperback | Euro [D] 49.95 ISBN 978-3-11-024561-5 Series: Patient Safety Also available as an eBook: ISBN 978-3-11-024562-2 € 49.95 24 x 17 cm. Approx. v, 250 pages. 20 fig. 25 tables Languages: English Type of Publication: Specialist Text

About this Title   

Concise information on the influence of herbs in laboratory testing Clinically relevant findings Toxicity of herbal products and interaction with drugs

Herbal supplements are available without prescription in many countries throughout the world and accounting for over $30 billion U.S dollar in sale. A majority of U.S population (25-40%) use herbal supplements while alternative medicines are major forms of therapy in third world countries used by as much as 80% population. Contrary to the popular belief that herbal remedies are safe and effective, many herbal supplements have known toxicity and unexpected laboratory test results may be the early indications of such toxicity. In addition, some herbal products such as St. John’s wort can interact with many Western drugs causing increased clearance of such drugs and hence treatment failure. This monograph would provide information on how herbal supplements affect laboratory test results thus patient’s safety. This monograph would provide a comprehensive and concise practical guide for laboratory professionals, physicians and other health care professionals. The emphasis of this monograph is to provide clinically relevant information rather than discussing in detail mechanisms of such effect, although brief explanations would be provided for such unexpected test results.

Subjects Medicine > Medicine, General Medicine > Clinical Medicine > Clinical Medicine, General Medicine > Pharmacy, General

Keywords Drugs; Herbage; Laboratory Medicine; Interaction; Herbal Drugs

Readership Laboratory Professionals

Please Send Your Orders to:

APD Singapore Pte Ltd (Malaysia Office) No. 22, 24 & 26 Jalan SS3/41, 47300, Petaling Jaya Tel: 603 78776063 / 5224 | Fax: 603 7877 3414 | Email: customersvc@apdkl.com


APD Singapore Pte Ltd (Malaysia) De Gruyter May 2011 - New In Medicine

Medical Errors and Patient Safety By Kalra, Jay Paperback | Euro [D] 49.95 ISBN 978-3-11-024949-1 Series: Patient Safety Also available as an eBook: ISBN 978-3-11-024950-7 € 49.95 24 x 17 cm. v, 150 pages. 10 fig. 10 tables Languages: English Type of Publication: Specialist Text

About this Title   

Reporting and reduction of medical errors Real cases from health care and beyond For physicians, clinical biochemists, research scientists, laboratory technologists

Is the reporting of medical errors changing? This book shows with real cases from health care and beyond that most errors come from flaws in the system. It also shows why they don’t get reported and how medical error disclosure around the world is shifting away from blaming people, to a “no-fault” model that seeks to improve the whole system of care. The book intends to provide an introduction to medical errors that result in preventable adverse events. It will examine issues that stymie efforts made to reduce preventable adverse events and medical errors, and will moreover highlight their impact on clinical laboratories and other areas, including educational, bioethical, and regulatory issues. Varying error rates of 0.1-9.3% in clinical diagnostic laboratories have been reported in the literature. While it is suggested that fewer errors occur in the laboratory than in other hospital settings, the quantum of laboratory tests used in healthcare entails that even a small error rate may reflect a large number of errors. The interdependence of surgical specialties, emergency rooms, and intensive care units - all of which are prone to higher rates of medical errors - with clinical diagnostic laboratories entails that reducing error rates in laboratories is essential to ensuring patient safety in other critical areas of healthcare. The author maintains that many such errors are preventable provided that appropriate attention is paid to systemic factors involved in laboratory errors. This book identifies possible intelligent system approaches that can be adopted to help control and eliminate these errors. It is a valuable tool for physicians, clinical biochemists, research scientists, laboratory technologists and anyone interested in reducing adverse events at all levels of healthcare processes.

Subjects Medicine > Clinical Medicine > Clinical Medicine, General

Keywords Medical Malpractice; Intensive Care; Laboratory Medicine; Emergency Medicine

Readership Physicians, Clinical Biochemists, Research Scientists, Laboratory Technologists, Laboratory and Healthcare Professionals


APD Singapore Pte Ltd (Malaysia) De Gruyter May 2011 - New In Medicine

Immunodiagnostics and Patient Safety by Sztefko, Krystyna Paperback | Euro [D] 49.95 ISBN 978-3-11-024947-7 Series: Patient Safety Also available as an eBook: ISBN 978-3-11-024948-4 € 49.95 24 x 17 cm. Approx. v, 215 pages. 15 fig. 10 tables Languages: English Type of Publication: Specialist Text

About this Title   

Basic principles of immunochemical methods Reduction of false results and improvement of patient’s care and patient’s safety Practical information for laboratory professionals, clinical chemists

Today most of immunochemistry methods for the determination of proteins, peptides, drugs, and many small molecules are fully automated, with good precision, excellent sensitivity and short reaction time. However, inaccuracy due to poor standardization and the presence of interfering substances in biological samples is still a serious and life-threatening issue. Proper validation of methods and quality assurance have little effect on frequency of occurrence of false positive or false negative results, which, if unrecognized, may lead to patient’s misdiagnosis, unnecessary treatment or even unnecessary surgery. Deep knowledge of basic principles of immunochemical methods (antigen-antibody reaction, standardization, matrix effect, limit of detection, crossreactivity, etc.), sources of analyte-independent interferences (preanalitycal errors, the presence of binding proteins, the presence of autoantibodies) and analyte-dependent interferences (presence of heterophilic antibodies, high-dose effect) are very important to understand, detect, reduce and/or eliminate the interferences. This book helps to reduce false results and, at the same time, improve patient’s care and patient’s safety.

Subjects Medicine > Clinical Medicine > Clinical Medicine, General

Keywords Immunodiagnostics; Interference; Laboratory Diagnostics; Patient Safety

Readership Laboratory Professionals, Clinical Chemists

Please Send Your Orders to:

APD Singapore Pte Ltd (Malaysia Office) No. 22, 24 & 26 Jalan SS3/41, 47300, Petaling Jaya Tel: 603 78776063 / 5224 | Fax: 603 7877 3414 | Email: customersvc@apdkl.com


APD Singapore Pte Ltd (Malaysia) De Gruyter May 2011 - New In Medicine

Liver Regeneration by Häussinger, Dieter Paperback | Approx. Euro [D] 49.95 / ISBN 978-3-11-025078-7 Series: De Gruyter Textbook Also available as an eBook: ISBN 978-3-11-025079-4 24 x 17 cm. Approx. xv, 180 pages. 100 fig. Languages: English Type of Publication: Textbook

About this Title   

An introduction to the topic of liver regeneration for graduate students and post-docs with information to help them develop their research strategies Treats topics central to the biomedical curriculum such as stem cell research, cancer biology, cell signaling and epigenetics Learning targets and study questions

understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.

Subjects Natural Sciences > Biology > Biology, General Natural Sciences > Biology > Physiology Natural Sciences > Biochemistry > Molecular Biology, Molecular Genetics Natural Sciences > Biochemistry > Molecular Medicine

Keywords Biochemistry; Liver; Molecular Biology; Regeneration; Therapy

Readership Graduate students and post-doctoral scientists in molecular biology, biochemistry and medicine


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