Forum FMH-Empresas – Biotecnol

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Biotecnol

Corporate Presentation

JosĂŠ LuĂ­s Moreira, Ph.D., MBA

Therapies for life

Chief Financial Officer & Chief Operational Officer


Development of new drugs


Development of new drugs

Research institutions


Development of new drugs

Multinational pharma corps.


Development of new drugs

Multinational pharma corps.


Development of new drugs

Biotec sme’s Biotecnol


Core Business

proprietary products strategy (long term)

services tactics (short term) 7


Core Business

oncology

● improved products to known targets

MoABs Biotecnol

● new products to new targets

2003 – ... hepathology Biotecnol

new pharma products

1998 – ...

● services to other

products

processes platforms

know-how

partnerships technologies

companies ● production of their own products ● optimization of production process ● as a service supply or in partnership 8


Corporate Organization

sa

inc

www.biotecnol.com

sa

www.rodonbiologics.com


Corporate Organization

Rodon Biologics

New Brunswick, NJ (USA)

Oeiras (Portugal)


Corporate Organization

Third party SA Potential Biotecnol outsourcing competitors

Out-licensing and own Tribody pipeline

Subcontracted Tribody development services

Non Tribody services to 3rd parties

Rodon Biologics

Tribody Platform  IP  US management  Know-How  Protocols  SOP’s  Commercial and R&D contracts

Site in New Brunswick, NJ

• Preclinical

Site in Oeiras, PT

• Process

development

development and manufacturing

• Future clinical

• Quality Control

development

System

Fully equipped laboratories Highly qualified and experienced scientists


State of the art R&D centre

• First Portuguese biopharmaceutical company to establish its activity outside a public R&D institute and become fully independent • Full internal capabilities for biological products development and manufacturing


State of the art R&D centre


Effective process development Technology

Economics

Manufacturing Business PROCESS Quality Control

Engineering

DEVELOPME NT Scale-up

Quality Assurance

Regulatory Affairs

Supply Chain and Logistics


Collaboration and technology licensing

Naples University


3rd party services


3rd party services

Product IL-13

Indication Uvidem速

Cardiotrophin1 transplants VB6-845-CL

oncology

GMCFS

stroke

Interferon

ACV

Bavituximab

HCV

ACE393

vaccine

Anti-Hsp90

metastatic melanoma

NS3

Hepatitis C

FastScreen ADC-1004

Stroke, trauma

Pro.insulin

Retinitis pigmentosa

R&D

Pre-clinic

Phase I

Phase II

Phase III

Partner


Tribody Platform single antigen target molecules CD3

CD19

CD3

CD19

CD20

CD3

CD20

X

X

dual antigen target molecules‫‏‬ CD3

CD19

CD3

CD20

CD19

CD3

X

CD20

X


Contacts

Biotecnol, SA Lagoas Park Edifício 7,1º Norte 2741-901 Oeiras Portugal

Biotecnol Pharmaceuticals, Inc 675 US Highway OneNorth Brunswick, NJ 08902 USA USA

jlm@biotecnol.com www.biotecnol.com www.rodonbiologics.com 19


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