24 minute read
NOVEL & NOTEWORTHY
Note worthyNote worthy
IN THIS ISSUE, ACG MAGAZINE Novel & Noteworthy celebrates the accomplishments of the College’s award winners and distinguished lecturers at the ACG 2019 Annual Scientific Meeting in San Antonio as well as the new cohort of ACG Masters (MACG). Some highlights of this year’s gathering in San Antonio included the fifth annual SCOPY Awards for colorectal cancer prevention and education, as well as the introduction of the EndoTitans competition for second- and third-year fellows, a test of cognitive and procedural skills in endoscopy. SiriusXM’s “Doctor Radio” broadcast returned to ACG for its third year with host Mark B. Pochapin, MD, FACG, the College’s President, and his invited guests discussing impactful clinical science and hot topics from ACG 2019.
[WINNERS] NEW ENDOTITANS HANDS-ON CHALLENGE SHOWCASES SKILLS
ACG 2019 FEATURED A NEW EVENT for fellows-in-training, the EndoTitans HandsOn Challenge! The challenge provides an opportunity for fellows to demonstrate both their knowledge and technical abilities in endoscopy. The competition began in August with a preliminary knowledge round open to all second- and third-year fellows. The top scoring fellows from each year were then invited to participate in a skills challenge. In the event’s inaugural year, Fady Haddad, MD, of Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital and Jason Pan, MD, of Brown University emerged victorious. The Winners will each receive a $1,000 grant to the ACG Annual Scientific Meeting in Nashville, TN, October 23–28, 2020.
Photo left: 3rd Year Fellows winner Fady Haddad, MD with the Judges. Left to Right: Seth A. Gross, MD, FACG (2019 Chair of the Educational Affairs Committee and Creator of EndoTitans); Rabia de Latour, MD; Laith H. Jamil, MD, FACG; and Vivek Kaul, MD, FACG (not pictured—Judge Aasma Shaukat, MD, MPH, FACG). Photo right: 2nd Year Fellows winner Jason Pan, MD with the Judges. Left to Right: Seth A. Gross, MD, FACG (2019 Chair of the Educational Affairs Committee and creator of EndoTitans); Rabia de Latour, MD; Laith H. Jamil, MD, FACG; and Vivek Kaul, MD, FACG (not pictured—Judge Aasma Shaukat, MD, MPH, FACG). (Photo top) Dr. Pochapin with L to R: David A. Greenwald, MD, FACG; Miguel D. Regueiro, MD, FACG; Sunanda V. Kane, MD, MSPH, FACG, and ACG Executive Director Bradley C. Stillman, Esq. This group covered key themes and significant findings from ACG 2019, as well as Dr. Regueiro’s David Sun Lecture on the concept of an “IBD home.” (Photo middle) Dr. Pochapin was joined by current and formers AJG editors-in-chief L to R: Eamonn M. M. Quigley, MD, MACG; Brennan M. R. Spiegel, MD, MSHS, FACG; William D. Chey, MD, FACG and Brian E. Lacy, MD, PhD, FACG who shared insights on functional GI disorders and research presented at ACG 2019. (Photo bottom) Dr. Pochapin had a lively discussion with L to R: Aasma Shaukat, MD, MPH, FACG; Joseph C. Anderson, MD, MHCDS, FACG; Laurie H. Parker, Executive Director, GIQuIC; and Folasade P. May, MD, PhD, MPhil on colorectal cancer screening, young onset disease, age recommendations for screening, and an update on the GIQuIC registry.
[AWARDEES] 2019 SHERMAN PRIZES
The Bruce and Cynthia Sherman Charitable Foundation announced the 2019 Sherman Prizes for outstanding achievements in the fight to overcome Crohn’s disease and ulcerative colitis. The three recipiences are:
Maria T. Abreu, MD, FACG Professor of Medicine and Microbiology and Immunology at the University of Miami Miller School of Medicine. Dr. Abreu, who is also the Director of the University of Miami Health System Crohn’s & Colitis Center.
Florian Rieder, MD, FACG, Assistant Professor in the Department of Inflammation and Immunity and part of the Department of Gastroenterology, Hepatology and Nutrition at Cleveland Clinic. Dr. Rieder received the Sherman Emerging Leader Prize.
William J. Sandborn, MD, FACG, Chief of the Division of Gastroenterology and Director of the Inflammatory Bowel Disease Center at University of California San Diego Health and Professor of Medicine at UC San Diego School of Medicine.
[ON THE AIR] LIVE FROM ACG 2019— SIRIUSXM’S “DOCTOR RADIO”
SiriusXM’s “Doctor Radio” returned for the third year in a row for a live broadcast during the Opening Welcome Reception at the ACG Annual Scientific Meeting at the Henry B. Convention Center in San Antonio, TX.
ACG President Mark B. Pochapin, MD, FACG served as the host of the two-hour show, which featured ACG officers and leaders in an engaging and far-reaching discussion of key clinical science from the meeting with implications for patient care. The College is grateful to SiriusXM and Doctor Radio for broadcasting live from ACG 2019. SiriusXM subscribers can listen to the show via SiriusXM On Demand.
[WINNERS] STATEN ISLAND LIFTS THE GI JEOPARDY TROPHY
The duo of Fady Haddad, MD, and Youssef El Douaihy, MD, claimed the GI Jeopardy title on behalf of Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital on Saturday, October 26 at the ACG Annual Scientific Meeting (ACG 2019) in San Antonio, TX.
For winning the competition, Haddad and El Douaihy will each receive a $1,000 grant to the ACG Annual Scientific Meeting in Nashville, TN, October 23–28, 2020.
The lively GI version of the television classic began over the summer, when GI training programs participated in the preliminary
[MILESTONES] FOUR MEMBERS HONORED AS MASTERS OF THE AMERICAN COLLEGE OF GASTROENTEROLOGY
MICHAEL CAMILLERI, MD, MACG Mayo Clinic, Rochester, MN
MARTIN L. FREEMAN, MD, MACG
University of Minnesota, Minneapolis, MN
G. RICHARD LOCKE, III, MD, MACG
(1961 – 2019)* Mayo Clinic, Rochester, MN
HARRY E. SARLES, JR., MD, MACG
Digestive Health Associates of Texas, Rockwall, TX
*Dr. Locke earned the distinction of MACG posthumously in October 2019. The College was saddened to learn of his passing on January 10, 2019.
READ about 2019 Masters at gi.org/awards
round, during which groups of GI fellows took an online test on various GI topics and diseases.
The live event, hosted by Ronald D. Szyjkowski, MD, FACG, allows the top five teams emerging from the preliminary round to vie for the winning spot. Teams also contended from Brown University, Indiana University School of Medicine, Stanford University, and the University of California San Diego (UCSD) Medical Center. The enthusiastic crowd watched as the field was narrowed to Staten Island, Indiana University, and UCSD, when Staten Island pulled ahead before the final question.
LEARN MORE about GI Jeopardy: bit.ly/GIJeopardy
[LECTURERS] ACG 2019 SPECIAL LECTURERS
MIGUEL D. REGUEIRO, MD, FACG The David Sun Lecture
“The IBD Medical Home and Neighborhood: It Takes a Village” Dr. Regueiro discussed the role of alternative models of care, such as the medical home, for the management of inflammatory bowel disease.
The David Sun Lecture was established by Mrs. Sun in memory of her husband, Dr. David Sun, an outstanding gastroenterologist and investigator.
CIARÁN P. KELLY, MD, FACG The American Journal Of Gastroenterology Lecture
“Celiac Disease: Myths and Mysteries?” Dr. Kelly explained how to appreciate the diverse clinical presentations of celiac disease, recognize the challenges and limitations of treatment with a gluten-free diet, and the need for non-dietary adjunctive therapies.
The American Journal of Gastroenterology Lecture was established in 2003 to provide a forum for the Editors of the College’s flagship scientific publication to select a key scientific topic for debate or discussion based on their evaluation of key controversies in clinical gastroenterology.
LINDA RABENECK, MD, MPH, MACG The J. Edward Berk Distinguished Lecture
“Post-Colonoscopy Colorectal Cancer: How Are We Doing?” Dr. Rabeneck shared best practices, incidences and causes, and reviewed approaches to reduce the risk of postcolonoscopy colorectal cancer in clinical practice.
The J. Edward Berk Distinguished Lecture is awarded to individuals prominent in gastroenterology or a related area and was established in recognition of the significant contributions made to clinical gastroenterology by J. Edward Berk, MD, MACG, during his long and distinguished clinical and academic career.
SURESH T. CHARI, MD, FACG The Emily Couric Memorial Lecture
“Early Detection of Pancreatic Cancer: Problems, Promise, and Prospects” Dr. Chari explained how to define “early” detection, recognize its benefits, and identify early detection barriers.
The Emily Couric Memorial Lecture, developed by the ACG, the Virginia Gastroenterological Society, and the Old Dominion Society of Gastroenterology Nurses and Associates, is given in honor of Virginia State Senator Emily Couric, who died of pancreatic cancer in October of 2001. Senator Couric was a strong advocate for health care issues, particularly in her instrumental work to pass the nation’s first legislation mandating health insurance coverage for colorectal cancer screening.
STEPHEN B. HANAUER, MD, FACG The David Y. Graham Lecture
“Mentoring Mentors” Dr. Hanauer shared how to gain a better understanding of mentoring towards leadership roles in gastroenterology.
The David Y. Graham Lecturer is a distinguished individual in the field of gastroenterology. This named lectureship was established in 2004 in recognition of the many contributions to clinical gastroenterology by David Y. Graham, MD, MACG, who gave the inaugural presentation in 2004.
1 6
9
7
4 2 3
8
5
[AWARDEES] ACG 2019 AWARDEES
SESHADRI T. CHANDRASEKAR, MD, FACG
Dr. Chandrasekar was presented with the Community Service Award, which is given to an ACG Member who has initiated or has been involved in volunteer programs or has provided extensive volunteer service post training. Dr. Chandrasekar provides free medical camps, health awareness programs, and concessional treatment, and has performed over 23,000 advanced endoscopy procedures in his local community of Chennai, Tamil Nadu, South India. He also created numerous patient materials, including Braille charts and medical cards to expedite treatment in emergencies.
Dr. Chandrasekar is the founding chairman and chief gastroenterologist at MedIndia Hospitals, a GI institution affiliated with Tamil Nadu State Dr. MGR Medical University (TNMGRMU) in Chennai, where he is an Adjunct Professor.
MANOOP BHUTANI, MD, FACG, FACP
Professor Manoop Bhutani, MD, FACG, FACP is the recipient of the International Leadership Award, which is given to a Fellow or Master of the ACG in recognition of outstanding and substantial contributions to gastroenterology, to the College, and to the international gastroenterology community. For over 20 years, Dr. Bhutani has been instrumental in advancing the field of endoscopic ultrasonography. In addition to his internationally known publications and speaking engagements, Dr. Bhutani has mentored and hosted visiting faculty and fellows from around the world. His long tenure serving on ACG’s International Relations Committee is a testament to his commitment to advancing the gastroenterology community worldwide.
He has authored more than 300 publications, acted as PI on many studies at MD Anderson, and served on many editorial boards. Dr. Bhutani is the Walter H. Wriston Distinguished Professor and Director of Endoscopic Research and Development at MD Anderson Cancer Center in Houston, Texas.
JAMIE S. BARKIN, MD, MACG
This year’s Berk/Fise Clinical Achievement awardee is ACG Past President Dr. Jamie S. Barkin, for his significant and distinguished contributions to clinical gastroenterology, particularly teaching and military medicine. This annual award recognizes not only clinical excellence, but also contributions in patient care, clinical science, clinical education, technological innovation, and public and community service. He became a Trustee of the College in 1980, served as President from 1989 to 1990, and has been active in numerous ACG committees.
Dr. Barkin is an innovator of endoscopic instrumentation and diagnostic techniques and was a pioneer in the development of small bowel enteroscopy and video-capsule endoscopy. In the pancreas, he was a pioneer of diagnostic aspiration of pancreatic lesions.
ALVIN M. ZFASS, MD, MACG
In recognition of his deep and abiding enthusiasm for the College, consistent and loyal service to ACG, and encouragement of young gastroenterologists to get involved, Dr. Alvin Zfass receives the College’s highest honor—the Samuel S. Weiss Award. This service award in commemoration of ACG’s founding father, Samuel S. Weiss, MD, is presented periodically to a Fellow of the College in recognition of outstanding career service to ACG. As a clinician, educator and mentor to many, Dr. Zfass exemplifies the ideals of service and dedication to ACG that are the hallmarks of the Weiss Award. According to one of his recommenders for this honor, Dr. Zfass has never missed an ACG Annual Scientific Meeting and to this day, “remains invested in the success of the ACG.” He steadfastly encourages his junior faculty at Virginia Commonwealth University to join and participate in the College. He has served on numerous ACG committees, including Educational Affairs, Public Policy, and Archives; served as ACG Governor for Virginia from 1988 to 1994; and was co-chair of the annual ACG Postgraduate Course in 1992.
2019 Special Lectures and Awardees, many pictured with ACG 2018-2019 President Sunanda V. Kane, MD, MSPH, FACG. (1) Miguel D. Regueiro, MD, FACG; (2) Ciarán P. Kelly, MD, FACG; (3) Linda Rabeneck, MD, MACG; (4) Suresh T. Chari, MD, FACG; (5) Stephen B. Hanauer, MD, FACG; (6) Seshadri T. Chandrasekar, MD, FACG; (7) Manoop Bhutani, MD, FACG; (8) Jamie S. Barkin, MD, MACG; (9) Alvin M. Zfass, MD, MACG
[AWARDS] SCOPY AWARDS: ACG RECOGNIZES 31 CRC AWARENESS PROJECTS
ACG celebrates the winners among a recordbreaking number of entries.
In 2019, a total of 31 SCOPY Awards were presented to an outstanding slate of CRC awareness champions. Their initiatives demonstrated a motivating spirit of collaboration, a dedication to reaching underserved communities, a focus on quality care and public health intervention, and an understanding that patient stories have an impact. The winners were celebrated during the 2019 SCOPY Awards Ceremony and Workshop, Sunday, October 27, 2019, at the ACG Annual Scientific Meeting in San Antonio.
The winning projects included international Dress in Blue Day participation, free colonoscopy clinics and university-wide community health events, extensive social media outreach, events as tributes to loved ones personally affected by CRC, and several videos—including a gastroenterologist’s own experience of getting a colonoscopy—among many other campaigns.
The initiatives “demonstrate sustained engagement with community members, effective collaboration to deliver comprehensive public awareness campaigns, and exemplary commitment to increasing of colorectal cancer screening,” said ACG Public Relations Committee Chair Sophie M. Balzora, MD, FACG, of the NYU School of Medicine in New York, NY.
LEARN MORE about the 2019 SCOPY Award winners: bit.ly/SCOPY19
[READING] MARTIN E. GORDON, MD, FACG PUBLISHES A NEW BOOK AT AGE 98
1. What are the origins of your interest in healing properties of plants and how long have you studied them?
The growth and beauty of plants have always intrigued me, but upon moving to Saint Louis, I was overcome with the voluminous activities of new plant sciences in this area. In fact, this area is becoming the epicenter of global plant sciences.
The ongoing need to amalgamate plant knowledge with medicinal practice became a fascinating calling, amplified by my addictive videography and silent photography.
2. What do gastroenterologists need to know about the world of medicinal plants?
The intimate association of the digestive diseases and plant biochemistry grows progressively as each of the sciences expand their own breakthroughs and understanding. Many illnesses are discovered and treated by knowledge of plants’ physiology as the treatment becomes associated with clues from plants. Many acute gastrointestinal illnesses are now amendable to plant substances but may also stimulate new discoveries.
These evolving discoveries within the gut microbiome predict diverse interactive beneficial food additives.
3. What was the most surprising MEDICINE or promising knowledge about plants, that you gained while writing this book? How intricate and complex Nature has provided us with subtle but very effective diagnostic and therapeutic aids. The application of ancient skills with the newer Plants R Cures explores the intersection of plants and medicine—now and in the past—while also offering a practical guide to the use of herbs to treat a large variety of ailments, from small to catastrophic. Dr Gordon tells us which plants promote good health and which ones you will be wise to avoid. The book also features anecdotal patient cases from his storied practice and world travels. With an almanac-style format and an abundance of graphics, this engaging book is designed to speak to laypeople and academics alike. “American Indians made Chaparral tea by grinding the leaves of the creosote bush. This desert shrub grows in Mexico and the southwestern United States and has a distinctive tar-like fragrance. Native Americans made tea from the leaves of this plant to treat chicken pox, colds, diarrhea, menstrual cramps, pain, snake bites, skin disorders and rheumatism. Over the years, it has also been prescribed for an even longer list of ailments ranging from acne to dandruff, diabetes, ulcers, UTI and even cancer.” DR MARTIN E. GORDON is a renowned gastroenterologist and expert in travel medicine. He served on the faculty of Yale Medical School for 40 years and headed the Yale medical library for an additional 10 years. During those years, he was asked often to diagnose patients with mysterious gastrointestinal symptoms, and he provided fellow physicians with guides to diagnoses and cures via educational materials, lectures and exhibits. He has authored many scientific publications—which focus on clinical solutions for the benefit of medical students, practitioners, and patients—and has received awards for his films and other efforts. His experiences have inspired him to focus on the often neglected plant sciences and their application to medical problems. U.S. $XX.XX sciences often yields practical answers to clinical puzzles. 4. At this point in your life, what motivates you as an author?
The ongoing interaction of plants, vectors, parasites and ourselves become vibrantly apparent as we delve into the silent world of plants. An example is that these disclose many fascinating “pearls”—such as bananas peels make excellent shoe polishers; the banana’s serotonin helps the post-liquor hangover condition and many other benefits.
5. As you reflect on the span of your career as a physician, are there insights about medicine or patient care that you would like to impart to your ACG colleagues?
By applying newer microscopic and basic genetic discoveries, we strengthen the ongoing connections of awareness of illness culminating in good health. We must constantly be aware of global toxicities that impact on our lives. An example: aiding the patient recall that the old wallpaper remodeling exposure to the arsenicalbased flowers may prevent diagnostic dilemmas.
Always recall Soma
Weiss’ admonition: “Any diagnosis is easy, once we think of it.”
Plants
Cures
Martin E. Gordon, M.D. Plants R Cures
An Almanac of Plants & Medicine
Martin E. Gordon, M.D.
[IN MEMORIAM] JAMES L. ACHORD, MD, MACG
ACG Past President, James L. Achord, MD, MACG passed away on November 18, 2019 at the age of 88. In addition to serving as ACG President from 1983–1984, Dr. Achord also served as ACG Governor for Mississippi and on various College Committees and as a Mississippi Governor for the American College of Physicians. He was named a Master of the College as well.
Dr. Achord was born in Dayton, OH and grew up in Alamo, GA. He attended Emory University and was accepted into the Emory School of Medicine at the end of his Junior year in college. After graduating from the Emory School of Medicine, he went on to serve in the Army Reserves.
As a physician leader, he Medical Director and Director of Medical Education at the Medical Center of Central Georgia, in Macon, GA, and was Professor of Medicine and Director of Digestive Diseases at the University of Mississippi Medical Center in Jackson, MS.
In 1991, ACG honored Dr.
Achord with the Samuel Weiss Award. This service award in commemoration of ACG’s founding father, Samuel S. Weiss, is presented periodically, and not necessarily annually, to a Fellow of the College in recognition of outstanding career service to ACG. He also was recognized by the Mississippi chapter of the American College of Physicians with their Laureate award.
ACG Past President Dr. Sidney J. Winawer offered this remembrance: “I had the pleasure of being a friend and colleague of Jim. He was a very special physician and human being. High integrity and wonderful collegiality. He will be missed.”
Dr. Stephen T. Amann, ACG’s Governor for Mississippi, recalls that many who trained under Dr. Achord noted that “his greatest gift was he always put the patient first, and by example taught us to do the same.”
Dr. Achord was preceded in death by his wife of 62 years, Pat Moore Achord. He is survived by a sister, his three children and 13 grandchildren.
MARCH 6–8
ACG/LGS REGIONAL POSTGRADUATE COURSE New Orleans, LA
Register: meetings.gi.org
MARCH 13–15
ACG/FGS ANNUAL SPRING SYMPOSIUM Naples, FL
Register: meetings.gi.org
MARCH 20–22
NORTH AMERICAN CONFERENCE OF GI FELLOWS (NACGF) Orlando, FL
Learn More: www.abstractscorecard.com/ cfp/submit/login.asp?EventKey=YCFOFAJN
JUNE 5
ACG'S IBD SCHOOL AT EASTERN REGIONAL
Washington, DC
Register: meetings.gi.org
MARCH 31
2020 GI TRAINING GRANTS DEADLINE Learn More: gi.org/gi-training-grants
JUNE 6–7
AUGUST 21
HEPATOLOGY SCHOOL AT MIDWEST REGIONAL St. Louis, MO
Register:
San Diego, CA
APRIL 15
Register: meetings.gi.org
MAY 31
2020 AWARDS NOMINATIONS DEADLINE
More Info: gi.org/awards
ENTER TO WIN A SCOPY
Submit your Entry: gi.org/scopy
AUGUST 22–23
MIDWEST REGIONAL POSTGRADUATE COURSE St. Louis, MO
Register: meetings.gi.org
THE AMERICAN COLLEGE THE AMERICAN COLLEGE OF GASTROENTEROLOGYOF GASTROENTEROLOGY
T he Pr emier GI Clinical Meeting & Post gradua te C ourse
ATTEND THE ACG 2020 The Premier GI Clinical Meeting & Postgraduate Course | OCTOBER 23–28, 2020 Save the Date! ATTEND THE ACG 2020 The Premier GI Clinical Meeting & Postgraduate Course | OCTOBER 23–28, 2020 Save the Date!THE AMERICAN COLLEGE OF GASTROENTEROLOGY ATTEND THE ACG 2020 ANNUAL SCIENTIFIC MEETING & POSTGRADUATE COURSE to learn the latest in clinical practice, exchange ideas with colleagues, and gain insight from the experts. ACG 2020 will be held in Nashville, Tennessee at the Music City Center. Continue to visit acgmeetings.gi.org for updated information. | OCTOBER 23–28, 2020 Save the Date!
ANNUAL SCIENTIFIC MEETINGANNUAL SCIENTIFIC MEETING & POSTGRADUATE COURSE& POSTGRADUATE COURSE
to learn the latest in clinical practice, exchange ideas with to learn the latest in clinical practice, exchange ideas with LEARN MORE: colleagues, and gain insight from the experts. ACG 2020 colleagues, and gain insight from the experts. ACG 2020 acgmeetings.gi.org will be held in Nashville, will be held in Nashville, Tennessee at the Music Tennessee at the Music City Center. City Center.
IMPORTANT SAFETY INFORMATION
SUPREP® Bowel Prep Kit (sodium sulfate, potassium sulfate and magnesium sulfate) Oral Solution is an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults. Most common adverse reactions (>2%) are overall discomfort, abdominal distention, abdominal pain, nausea, vomiting and headache. Use is contraindicated in the following conditions: gastrointestinal (GI) obstruction, bowel perforation, toxic colitis and toxic megacolon, gastric retention, ileus, known allergies to components of the kit. Use caution when prescribing for patients with a history of seizures, arrhythmias, impaired gag reflex, regurgitation or aspiration, severe active ulcerative colitis, impaired renal function or patients taking medications that may affect renal function or electrolytes. Use can cause temporary elevations in uric acid. Uric acid fluctuations in patients with gout may precipitate an acute flare. Administration of osmotic laxative products may produce mucosal aphthous ulcerations, and there have been reports of more serious cases of ischemic colitis requiring hospitalization. Patients with impaired water handling who experience severe vomiting should be closely monitored including measurement of electrolytes. Advise all patients to hydrate adequately before, during, and after use. Each bottle must be diluted with water to a final volume of 16 ounces and ingestion of additional water as recommended is important to patient tolerance.
BRIEF SUMMARY: Before prescribing, please see Full Prescribing Information and Medication Guide for SUPREP® Bowel Prep Kit (sodium sulfate, potassium sulfate and magnesium sulfate) Oral Solution. INDICATIONS AND USAGE: An osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults. CONTRAINDICATIONS: Use is contraindicated in the following conditions: gastrointestinal (GI) obstruction, bowel perforation, toxic colitis and toxic megacolon, gastric retention, ileus, known allergies to components of the kit. WARNINGS AND PRECAUTIONS: SUPREP Bowel Prep Kit is an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults. Use is contraindicated in the following conditions: gastrointestinal (GI) obstruction, bowel perforation, toxic colitis and toxic megacolon, gastric retention, ileus, known allergies to components of the kit. Use caution when prescribing for patients with a history of seizures, arrhythmias, impaired gag reflex, regurgitation or aspiration, severe active ulcerative colitis, impaired renal function or patients taking medications that may affect renal function or electrolytes. Pre-dose and post-colonoscopy ECGs should be considered in patients at increased risk of serious cardiac arrhythmias. Use can cause temporary elevations in uric acid. Uric acid fluctuations in patients with gout may precipitate an acute flare. Administration of osmotic laxative products may produce mucosal aphthous ulcerations, and there have been reports of more serious cases of ischemic colitis requiring hospitalization. Patients with impaired water handling who experience severe vomiting should be closely monitored including measurement of electrolytes. Advise all patients to hydrate adequately before, during, and after use. Each bottle must be diluted with water to a final volume of 16 ounces and ingestion of additional water as recommended is important to patient tolerance. Pregnancy: Pregnancy Category C. Animal reproduction studies have not been conducted. It is not known whether this product can cause fetal harm or can affect reproductive capacity. Pediatric Use: Safety and effectiveness in pediatric patients has not been established. Geriatric Use: Of the 375 patients who took SUPREP Bowel Prep Kit in clinical trials, 94 (25%) were 65 years of age or older, while 25 (7%) were 75 years of age or older. No overall differences in safety or effectiveness of SUPREP Bowel Prep Kit administered as a split-dose (2-day) regimen were observed between geriatric patients and younger patients. DRUG INTERACTIONS: Oral medication administered within one hour of the start of administration of SUPREP may not be absorbed completely. ADVERSE REACTIONS: Most common adverse reactions (>2%) are overall discomfort, abdominal distention, abdominal pain, nausea, vomiting and headache. Oral Administration: Split-Dose (Two-Day) Regimen: Early in the evening prior to the colonoscopy: Pour the contents of one bottle of SUPREP Bowel Prep Kit into the mixing container provided. Fill the container with water to the 16 ounce fill line, and drink the entire amount. Drink two additional containers filled to the 16 ounce line with water over the next hour. Consume only a light breakfast or have only clear liquids on the day before colonoscopy. Day of Colonoscopy (10 to 12 hours after the evening dose): Pour the contents of the second SUPREP Bowel Prep Kit into the mixing container provided. Fill the container with water to the 16 ounce fill line, and drink the entire amount. Drink two additional containers filled to the 16 ounce line with water over the next hour. Complete all SUPREP Bowel Prep Kit and required water at least two hours prior to colonoscopy. Consume only clear liquids until after the colonoscopy. STORAGE: Store at 20°-25°C (68°-77°F). Excursions permitted between 15°-30°C (59°-86°F). Rx only. Distributed by Braintree Laboratories, Inc. Braintree, MA 02185
For additional information, please call 1-800-874-6756 or visit www.suprepkit.com
#1 MOST PRESCRIBED,
BRANDED BOWEL PREP KIT1
WITH MORE THAN 15 MILLION KITS DISPENSED SINCE 20101
A CLEAN SWEEP
EFFECTIVE RESULTS IN ALL COLON SEGMENTS2
· SUPREP® Bowel Prep Kit has been FDA-approved as a split-dose oral regimen3 · >90% of patients had no residual stool in all colon segments2*†
These cleansing results for the cecum included 91% of patients2*†
SUPREP Bowel Prep Kit also achieved ≥64% no residual fl uid in 4 out of 5 colon segments (ascending, transverse, descending, and sigmoid/rectum)2*†
Aligned with Gastrointestinal Quality Improvement Consortium (GIQuIC) performance target of ≥85% quality cleansing for outpatient colonoscopies.4
*This clinical trial was not included in the product labeling. †Based on investigator grading. References: 1. IQVIA. National Prescription Audit Report. September 2018. 2. Rex DK, DiPalma JA, Rodriguez R, McGowan J, Cleveland M. A randomized clinical study comparing reduced-volume oral sulfate solution with standard 4-liter sulfate-free electrolyte lavage solution as preparation for colonoscopy. Gastrointest Endosc. 2010;72(2):328-336. 3. SUPREP Bowel Prep Kit [package insert]. Braintree, MA: Braintree Laboratories, Inc; 2017. 4. Rex DK, Schoenfeld PS, Cohen J, et al. Quality indicators for colonoscopy. Gastrointest Endosc. 2015;81(1):31-53.
