HCM

Page 1

;GENET IC DISORDERS; Liceo Scientifico S. Anna

Francesca Bardazzi

31.05.2013

Vale

e l a r o p m e T ntina

Andrea S ilvano

Giulia Actis Dato


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WHAT’S HCM ? Hypertrophic cardiomyopathy (HCM) is an inherited disease of the heart muscle. HCM can cause the wall (that is called Septum) of the heart muscle to thicken. When the wall get too thick, the heart muscle functions inefficiently, causing some patients to have obstruction to blood flow from the heart. HCM is also associated with abnormal heart rhythms, which can sometimes be life threatening.


A SYMPTOMS A Shortness of breath

Palpitations or sensation of feeling the heart beat

Chest pain or discomfort Dizziness Fainting


O HCM INHERITANCE O

Familiar hypertrophic cardiomyopathy is inherited as an autosomal dominant trait. Since HCM is typically an autosomal dominant trait, children of an HCM parent have 50% chance of inheriting the disease-causing mutation. Hypertrophic cardiomyopathy is usually caused by gene mutations. It's thought these mutations cause the heart muscle to grow abnormally thick.


WHAT’S HCOM ? ( People with hypertrophic cardiomyopathy also have an abnormal arrangement of heart muscle fibers. The heart muscle cells become jumbled, known as myofiber disarray. This disarray can contribute to an irregular heartbeat (arrhythmia) in some people. The severity of hypertrophic cardiomyopathy varies widely. Most people with hypertrophic cardiomyopathy have a form of the disease in which the wall (septum) between the two bottom chambers of the heart (the ventricles) becomes enlarged and obstructs blood flow. This is sometimes referred to as hypertrophic cardiomyopathy with obstruction or hypertrophic obstructive cardiomyopathy.


SURGERY x Alcohol Septal Ablation

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Surgical Myectomy

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D SITOGRAPHY D •www.cardiomiopatia-ipertrofica.it •http://www.cardiomyopathy.org/Treating-obstruction-in-hypertrophiccardiomyopathy.html

•http://en.wikipedia.org/wiki/Hypertrophic_cardiomyopathy •http://www.youtube.com/watch?v=ZkG55OMxC7A •http://www.youtube.com/watch?v=rXyVzOmyWfo •http://www.youtube.com/watch?v=H2564NC3B-8 •http://www.youtube.com/watch?v=5Poffmh1ONQ


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