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ANZUP ANNUAL REPORT 2022
RESEARCH HIGHLIGHTS
Publications, Posters & Presentations 2021/22 Publications ENZAMET Research Review, 1 May 2021 EDUCATIONAL SERIES – Enzalutamide in men with metastatic hormone-sensitive prostate cancer: focus on the ARCHES and ENZAMET trials. Ian D. Davis SUBDUE-1 BJU International, 6 May 2021 A phase I open label dose-escalation study to evaluate the tolerability, safety and immunological efficacy of sub-urothelial durvalumab injection in adults with muscle-invasive or high-risk non-muscle-invasive bladder cancer (SUBDUE-1, SUB-urothelial DUrvalumab injection-1 study): clinical trial protocol Andrew Moe, Elizabeth Liow, Andrew Redfern, Nicole Swarbrick, Tom Ferguson, Ian D. Davis, Dickon Hayne ENZAMET European Urology, 22 May 2021 Overall Survival of Men with Metachronous Metastatic Hormone-sensitive Prostate Cancer Treated with Enzalutamide and Androgen Deprivation Therapy. Christopher J Sweeney, Andrew J Martin, Martin R Stockler, Stephen Begbie, Kim N Chi, Simon Chowdhury, Xanthi Coskinas, Mark Frydenberg, Wendy E Hague, Lisa G Horvath, Anthony M Joshua, Nicola J Lawrence, Gavin M Marx, John McCaffrey, Ray McDermott, Margaret McJannett, Scott A North, Francis Parnis, Wendy Parulekar, David W Pook, M Neil Reaume, Shahneen K Sandhu, Alvin Tan, Thean Hsiang Tan, Alastair Thomson, Emily Tu, Francisco Vera-Badillo, Scott G Williams, Sonia Yip, Alison Y Zhang, Robert R Zielinski, Ian D Davis, ENZAMET Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP) ENZA-p BJU International, 24 May 2021 ENZA-p trial protocol: A randomised phase II trial using PSMA as a therapeutic target and prognostic indicator in men with metastatic castration-resistant prostate cancer treated with enzalutamide (ANZUP 1901). Louise Emmett, Shalini Subramaniam, Anthony Joshua, Megan Crumbaker, Andrew Martin, Alison Y. Zhang, Nisha
Rana, Ailsa Langford, Jenna Mitchell, Sonia Yip, Roslyn Francis, Michael S. Hofman, Shahneen Sandhu, Arun Azad, Craig Gedye, Margaret McJannett, Martin R. Stockler, and Ian D. Davis on behalf of the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP) and the ENZA-p investigators. Pain Free TRUS-B BJU International, 17 July 2021 ‘Pain-free TRUS B’: a phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography-guided prostate biopsy (ANZUP 1501) Dickon Hayne, Jeremy Grummet, David Espinoza, Steve P. McCombie, Venu Chalasani, Kate S. Ford, Mark Frydenberg, Peter Gilling, Barbara Gordon, Cynthia Hawks, Alex Konstantatos, Andrew J. Martin, Anthony Nixon, Colin O’Brien, Manish I. Patel, Shomik Sengupta, Shekib Shahbaz, Shalini Subramaniam, Scott Williams, Henry H. Woo, Martin R. Stockler, Ian D. Davis, Nick Buchan, on behalf of the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP) TheraP BMJ Journals, 9 August 2021 Advanced prostate cancer experimental radioactive treatment—clinical trial decision making: patient experiences Bianca Viljoen, Michael S Hofman, Suzanne K Chambers, Jeff Dunn, Haryana Dhillon, Ian D Davis and Nicholas Ralph