Division Research Commission grants

C3-Coating: The C3 project is a collaborative and knowledge exchange grant awarded by the KULeuven to Fintan Moriarty, ARI and Prof Hans Steenackers of KULeuven to further test an anti-biofilm technology using the ARI’s preclinical testing facility and to transfer the knowledge to the veterinary facility in Leuven, total value CHF 120’000.

HiLo: The HiLo project is a collaborative project with ARI, Fintan Moriarty, funded by the University Hospital Regensburg (Partner, Volker Alt) to investigate the role of virulence factors in Staphylococcus aureus fracture-related infection, CHF 45’000.

IsmarD "Smart, Multifunctional Dental Implants: A Solution for Peri-Implantitis and Bone Loss" (NMBP-TR-IND-2018-2020): To address the clinical problem of bacterial biofilm formation and peri-implantitis, the I-SMarD project proposes to develop multi-functional dental implants that can respond to environmental threats such as bacteria by releasing nanoparticles and antibiotics, will match the anatomical characteristics of dental tissues and offer the potential to monitor the healing process after surgery. The project partners include Peter Varga (ARI). Total budget EUR 5.1 million over a project duration of 4 years (2020-2024), the ARI budget is EUR 618’000.

BoneFix: "A Paradigm Shift in Fracture Fixations via On-Site Fabrica-tion of Bone Restoration Patches" (H2020-EICFETPROACT-2019): BoneFix is a new adhesive based bone fixation and restoration technology which aims to supplant metal fixators and transplants as the gold standard in fracture fixation and reconstruction. Total budget EUR 4.0 million over a project duration of 4 years (2020-2024), the ARI budget is EUR 400’000, with Peter Varga involved as WP leader.

8.2 New AO Foundation intramural funding (grants beyond ARI retainer & Clinical Division Research Commission grants)

AO Development Incubator (AODI): 'AO Fracture Monitor – Development Phase'. Main applicant and coordinator of the project is Markus Windolf (ARI). Overall funding is CHF 4.0 million for 4 years. The AO Fracture Monitor was created in ARI and is believed to be a major change to internal fracture fixation in the future.

AO Development Incubator (AODI): 'Biphasic Plating – Next Generation Locked Plating'. Project partners are Markus Windolf (ARI) and Professor Devakar Epari (Queensland University of Technology). Overall project funding is CHF 1.7 million for 4 years.

AO Development Incubator (AODI): 'Growth modulation implant'. Main applicant and project coordinator is Markus Windolf (ARI). Overall funding is CHF 1.6 million for 4 years. Novel implant approach to significantly improve treatment of growth deformities in children.

AO Strategy Fund (AOSF): 'OSApp: Virtual osteosynthesis tool for surgical education'. Main applicant and coordinator of the project is Peter Varga (ARI). Project funding is CHF 522'000 for 2.5 years.

AO Strategy Fund (AOSF): 'Digitally enhanced hands-on surgical training'. Main applicant and coordinator of the project is Jan Buschbaum (ARI). Project funding is CHF 482'000 for 3 years.

AO Development Incubator (AODI): Antibiotic loaded hydrogel for infection prophylaxis in open fractures. Investigators: Fintan Moriarty, Matteo D'Este and Andrea Montali. Overall project funding is CHF 400'000 for 2 years.