Reaxys
PubChem
eMolecules
Reactions (62)
Substances (6)
Structure
Citations (12)
Structure/Compound Data Chemical Name: S 37260 Reaxys Registry Number: 2098869
CAS Registry Number: 54804-28-3 Type of Substance: isocyclic Molecular Formula: C11H17NO2
Linear Structure Formula: C11H17NO2
Molecular Weight: 195.261
InChI Key: WDGSTBTXYPCSLW-UHFFFAOYSA-N
1
N° of preparations All Preps | All Reactions 2 prep out of 5 reactions.
Synthesize | Hide Details Find similar Chemical Names and Synonyms S 37260, 1-phenyl-2-methyl-3-aza-1,5-pentane diol, 2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol, 2-(β-Oxy-aethylamino)-1-phenyl-propanol-(1), 2-(2-Hydroxy-aethylamino)-1-phenyl-propan-1-ol, 1-Phenyl-2-<N-(β-hydroxyaethyl)-amino>-propanol-(1), N-<2-Hydroxy-ethyl>-(+-)-norephedrin Identification Substance Label (3) Label
Reference
1b
Kamel; Osman
Pharmazie, 1985 , vol. 40, # 1 p. 58 - 59 Title/Abstract Full Text View citing articles Show Details
10
Bonningue et al.
Phosphorus and Sulfur and the Related Elements, 1979 , vol. 5, p. 291,293, 298 Full Text Show Details
I
Klosa,J.
Available Data
N° of ref.
Identification Physical Data (5) Spectra (1) Bioactivity (1)
9
Journal fuer Praktische Chemie (Leipzig), 1963 , vol. 21, p. 12 - 17 Full Text View citing articles Show Details
Derivative (3) Comment (Derivative)
Reference
*HCL: NMR
Bonningue et al.
Phosphorus and Sulfur and the Related Elements, 1979 , vol. 5, p. 291,293, 298 Full Text Show Details
Hydrochlorid: C11H17NO2*HCl, F: 166grad-168grad (Ae., Propan-2-ol)
Klosa,J.
Journal fuer Praktische Chemie (Leipzig), 1963 , vol. 21, p. 12 - 17 Full Text View citing articles Show Details
HCl-Salz: F: 166grad
Egyesult Gyogyszer es Tapszergyar
Patent: HU149550 , 1960 ; Chem.Abstr., 1963 , vol. 58, # 4582d Full Text Show Details
Physical Data Melting Point (4) Melting Point
Solvent (Melting Point)
Reference
115 °C
Bonningue et al.
Phosphorus and Sulfur and the Related Elements, 1979 , vol. 5, p. 291,293, 298 Full Text Show Details
110 - 112 °C
Klosa,J.
Journal fuer Praktische Chemie (Leipzig), 1963 , vol. 21, p. 12 - 17 Full Text View citing articles Show Details
95 - 97 °C
Industria Chimica Profarmaco, S.a.v.C.
Patent: GB886035 , 1959 ; Chem.Abstr., 1963 , vol. 58, # 533a Full Text Show Details
109 °C
Skita; Keil
Chemische Berichte, 1930 , vol. 63, p. 34,46, 47 Chemische Berichte, 1932 , vol. 65, p. 424,428 Full Text View citing articles Show Details
ethanol
Further Information (1) Description (Further Information)
Reference
Further information
Egyesult Gyogyszer es Tapszergyar
Patent: HU149550 , 1960 ; Chem.Abstr., 1963 , vol. 58, # 4582d Full Text Show Details
Spectra NMR Spectroscopy (1) Description (NMR Spectroscopy)
Reference
NMR
Bonningue et al.
Phosphorus and Sulfur and the Related Elements, 1979 , vol. 5, p. 291,293, 298 Full Text Show Details
Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
Bioactivities present
Reference
Klosa,J.
Journal fuer Praktische Chemie (Leipzig), 1963 , vol. 21, p. 12 - 17 Full Text View citing articles Show Details
Manske; Johnson
Journal of the American Chemical Society, 1929 , vol. 51, p. 1908 Full Text View citing articles Show Details
Skita; Keil
Chemische Berichte, 1930 , vol. 63, p. 34,46, 47 Chemische Berichte, 1932 , vol. 65, p. 424,428 Full Text View citing articles Show Details
Egyesult Gyogyszer es Tapszergyar
Patent: HU149550 , 1960 ; Chem.Abstr., 1963 , vol. 58, # 4582d Full Text Show Details
Industria Chimica Profarmaco, S.a.v.C.
Patent: GB886035 , 1959 ; Chem.Abstr., 1963 , vol. 58, # 533a Full Text Show Details
Bonningue et al.
Phosphorus and Sulfur and the Related Elements, 1979 , vol. 5, p. 291,293, 298 Full Text Show Details
Klosa
Journal fuer Praktische Chemie (Leipzig), 1969 , vol. 311, p. 520 Full Text Show Details
Kamel; Osman
Pharmazie, 1985 , vol. 40, # 1 p. 58 - 59 Title/Abstract Full Text View citing articles Show Details
Mukherjee; Caron; Mullikin; Lefkowitz
Molecular pharmacology, 1976 , vol. 12, # 1 p. 16 - 31 Title/Abstract Full Text Show Details
Chemical Name: (1S,2R)-2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol Reaxys Registry Number: 4795946
CAS Registry Number: 54804-28-3, 110612-16-3 Type of Substance: isocyclic Molecular Formula: C11H17NO2
Linear Structure Formula: C11H17NO2
Molecular Weight: 195.261
InChI Key: WDGSTBTXYPCSLW-MWLCHTKSSA-N
2
0 prep out of 4 reactions.
1
0 prep out of 3 reactions.
1
Synthesize | Hide Details Find similar Chemical Names and Synonyms (1S,2R)-2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol, D-N-<β-Hydroxy-ethyl>-norephedrin Chemical Name: (1R,2S)-2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol Reaxys Registry Number: 4795947
CAS Registry Number: 54804-28-3, 110612-16-3 Type of Substance: isocyclic Molecular Formula: C11H17NO2
Linear Structure Formula: C11H17NO2
Molecular Weight: 195.261
InChI Key: WDGSTBTXYPCSLW-ONGXEEELSA-N
3
Synthesize | Hide Details Find similar Chemical Names and Synonyms (1R,2S)-2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol Chemical Name: (1RS,2SR)-2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol Reaxys Registry Number: 4795948
CAS Registry Number: 54804-28-3, 110612-16-3 Type of Substance: isocyclic
3 prep out of 45 reactions.
Identification Physical Data (1)
3
4
Molecular Formula: C11H17NO2
Linear Structure Formula: C11H17NO2
Molecular Weight: 195.261
InChI Key: WDGSTBTXYPCSLW-MWLCHTKSSA-N
Synthesize | Hide Details Find similar Chemical Names and Synonyms (1RS,2SR)-2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol, Opt.-inakt. 2-<2-Hydroxy-ethylamino>-1-phenyl-propan-1-ol, DL-N-<β-Hydroxy-ethyl>norephedrin, N-(2-Hydroxy-ethyl)-norephedrin Identification Substance Label (1) Label
Reference
IIId
Weichet,J. et al.
Collection of Czechoslovak Chemical Communications, 1961 , vol. 26, p. 2040 - 2044 Full Text View citing articles Show Details
Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
110 - 111.5 °C
diethyl ether
Kalm,M.J.
Journal of Organic Chemistry, 1960 , vol. 25, p. 1929 - 1937 Full Text View citing articles Show Details
Chemical Name: 2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol; hydrochloride
5
Reaxys Registry Number: 3717621
CAS Registry Number: 63991-20-8 Type of Substance: isocyclic Molecular Formula: C11H17NO2*ClH Linear Structure Formula: C11H17NO2*ClH Molecular Weight: 231.722
InChI Key: YGIPNGHJLVOBQO-UHFFFAOYSA-N
0 prep out of 5 reactions.
Synthesize | Hide Details Find similar Chemical Names and Synonyms 2-(2-hydroxy-ethylamino)-1-phenyl-propan-1-ol; hydrochloride, 2-(2-Hydroxy-aethylamino)-1-phenyl-propan-1-ol; Hydrochlorid, α-{1-[(2hydroxyethyl)amino]ethyl}benzyl alcohol hydrochloride Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
166 °C
acetone methanol
Manske; Johnson
Journal of the American Chemical Society, 1929 , vol. 51, p. 1908 Full Text View citing articles Show Details
Physical Data (2)
3
Skita; Keil
Chemische Berichte, 1930 , vol. 63, p. 34,46, 47 Chemische Berichte, 1932 , vol. 65, p. 424,428 Full Text View citing articles Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
Nadeln
Manske; Johnson
Journal of the American Chemical Society, 1929 , vol. 51, p. 1908 Full Text View citing articles Show Details
Skita; Keil
Chemische Berichte, 1930 , vol. 63, p. 34,46, 47 Chemische Berichte, 1932 , vol. 65, p. 424,428 Full Text View citing articles Show Details
Reaxys Registry Number: 7276032
Type of Substance: isocyclic Molecular Formula: C11H17NO2*ClH Linear Structure Formula: C11H17NO2*ClH Molecular Weight: 231.722
InChI Key: YGIPNGHJLVOBQO-FOKYBFFNSA-N
no reactions.
6
Synthesize | Hide Details Find similar
Identification Substance Label (1) Label
Reference
zu IIId
Weichet,J. et al.
Collection of Czechoslovak Chemical Communications, 1961 , vol. 26, p. 2040 - 2044 Full Text View citing articles Show Details
Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
164 - 166 °C
acetone
Weichet,J. et al.
Collection of Czechoslovak Chemical Communications, 1961 , vol. 26, p. 2040 - 2044 Full Text View citing articles Show Details
Identification Physical Data (1)
1