Reaxys
PubChem
eMolecules
LabNetwork
Reactions (1487)
Substances (26)
Structure
Citations (467)
Structure/Compound Data Chemical Name: tropinone Reaxys Registry Number: 2329
CAS Registry Number: 532-24-1 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: OC7H10NCH3
Molecular Weight: 139.197 InChI Key: QQXLDOJGLXJCSE-UHFFFAOYSA-N
1
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropinone, Tropan-3-on Identification Substance Label (29) Label
Reference
1
Thompson, Philip E.; Steer, David L.; Aguilar, Marie-Isabel; Hearn, Milton T. W.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 19 p. 2699 - 2704 Title/Abstract Full Text View citing articles Show Details
Badio, Barbara; Garraffo, H. Martin; Plummer, Carlton V.; Padgett, William L.; Daly, John W.
European Journal of Pharmacology, 1997 , vol. 321, # 2 p. 189 - 194 Title/Abstract Full Text View citing articles Show Details
Lyapkalo, Ilya M.; Hoegermeier, Jens; Reissig, Hans-Ulrich
Tetrahedron, 2004 , vol. 60, # 35 p. 7721 - 7729 Title/Abstract Full Text View citing articles Show Details
Zheng, Guangrong; Dwoskin, Linda P.; Crooks, Peter A.
N° of preparations All Preps | All Reactions 39 prep out of 1027 reactions.
Available Data
N° of ref.
Identification Physical Data (43) Spectra (19) Bioactivity (18) Other Data (4)
335
Synthetic Communications, 2004 , vol. 34, # 11 p. 1931 - 1942 Title/Abstract Full Text View citing articles Show Details
Pham-Huu, Duy-Phong; Deschamps, Jeffrey R.; Liu, Shanghao; Madras, Bertha K.; Meltzer, Peter C.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 2 p. 1067 - 1082 Title/Abstract Full Text View citing articles Show Details
Willand, Nicolas; Folleas, Benoit; Boutillon, Christophe; Verbraeken, Liesbeth; Gesquiere, Jean-Claude; Tartar, Andre; Deprez, Benoit
Tetrahedron Letters, 2007 , vol. 48, # 29 p. 5007 - 5011 Title/Abstract Full Text View citing articles Show Details
Naeja Pharmaceutical Inc.
Patent: US2011/288063 A1, 2011 ; Title/Abstract Full Text Show Details
Stefanowicz, Jacek; Słowiński, Tomasz; Wróbel, Martyna Zofia; Herold, Franciszek; Gomółka, Anna Edyta; Wesołowska, Anna; Jastrzębska-Więsek, Magdalena; Partyka, Anna; Andres-Mach, Marta; Czuczwar, Stanisław Jerzy; Łuszczki, Jarogniew Jacek; Zagaja, Mirosław; Siwek, Agata; Nowak, Gabriel; Żołnierek, Maria; Bączek, Tomasz; Ulenberg, Szymon; Belka, Mariusz; Turło, Jadwiga
Bioorganic and Medicinal Chemistry, 2016 , vol. 24, # 18 p. 3994 - 4007 Title/Abstract Full Text View citing articles Show Details
1j
Alonso, Francisco; Arroyo, Adrián; Martín-García, Iris; Moglie, Yanina
Advanced Synthesis and Catalysis, 2015 , vol. 357, # 16-17 p. 3549 - 3561 Title/Abstract Full Text View citing articles Show Details
1d
Abbiati, Giorgio; Arcadi, Antonio; Bianchi, Gabriele; Di Giuseppe, Sabrina; Marinelli, Fabio; Rossi, Elisabetta
Journal of Organic Chemistry, 2003 , vol. 68, # 18 p. 6959 - 6966 Title/Abstract Full Text View citing articles Show Details
Chaudhary, Anurag; Sharma; Bhardwaj, Gautam; Jain, Vaibhav; Bharatam; Shrivastav, Birendra; Roy
Medicinal Chemistry Research, 2013 , vol. 22, # 12 p. 5654 - 5669 Title/Abstract Full Text View citing articles Show Details
1f
Li, Yuanming; Jia, Fan; Li, Zhiping
Chemistry - A European Journal, 2013 , vol. 19, # 1 p. 82 - 86 Title/Abstract Full Text View citing articles Show Details
1b
Yu, Yang; Yang, Xiao-Fei; Xu, Chao-Fan; Ding, Chang-Hua; Hou, Xue-Long
Organic Letters, 2013 , vol. 15, # 15 p. 3880 - 3883 Title/Abstract Full Text View citing articles Show Details
26
Narayanan, Nara
Patent: US2013/137873 A1, 2013 ; Title/Abstract Full Text Show Details
4
Boyd, Robert E.; Carson, John R.; Codd, Ellen E.; Gauthier, A. Diane; Neilson, Lou Anne; Zhang, Sui-Po
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 10 p. 1109 - 1111 Title/Abstract Full Text View citing articles Show Details
El Bazaoui, Ahmed; Ahmed Bellimam, My; Soulaymani, Abdelmajid
Fitoterapia, 2011 , vol. 82, # 2 p. 193 - 197 Title/Abstract Full Text View citing articles Show Details
1px
NEUROSCIENZE PHARMANESS S.C. A.R.L.
Patent: US2011/152238 A1, 2011 ; Title/Abstract Full Text Show Details
1a
Majewski, Marek; Wang, Fan
Tetrahedron, 2002 , vol. 58, # 23 p. 4567 - 4571 Title/Abstract Full Text View citing articles Show Details
NEUROSCIENZE PHARMANESS S.C.A.R.L.
Patent: US2010/29622 A1, 2010 ; Title/Abstract Full Text Show Details
Neuroscienze Pharmaness S.C. A R.L.
Patent: EP2149575 A1, 2010 ; Title/Abstract Full Text Show Details
14; 23
Brock University
Patent: US2009/5565 A1, 2009 ; Title/Abstract Full Text Show Details
32
Kuethe, Jeffrey T.; Varon, Jack; Childers, Karla G.
Tetrahedron, 2007 , vol. 63, # 46 p. 11489 - 11502 Title/Abstract Full Text View citing articles Show Details
SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/118724 A1, 2008 ; Title/Abstract Full Text Show Details
41a
THE UNIVERSITY OF LIVERPOOL; LIVERPOOL SCHOOL OF TROPICAL MEDICINE
Patent: WO2008/38030 A2, 2008 ; Title/Abstract Full Text Show Details
4a
Watson, Robert J.; Allen, Daniel R.; Birch, Helen L.; Chapman, Gayle A.; Galvin, Frances C.; Jopling, Louise A.; Knight, Roland L.; Meier, Dorica; Oliver, Kathryn; Meissner, Johannes W.G.; Owen, David A.; Thomas, Elizabeth J.; Tremayne, Neil; Williams, Sophie C.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 1 p. 147 - 151 Title/Abstract Full Text View citing articles Show Details
12
Calogeropoulou, Theodora; Angelou, Panagiotis; Detsi, Anastasia; Fragiadaki, Irene; Scoulica, Effie
Journal of Medicinal Chemistry, 2008 , vol. 51, # 4 p. 897 - 908 Title/Abstract Full Text View citing articles Show Details
13
Ellis, Gemma L.; Amewu, Richard; Sabbani, Sunil; Stocks, Paul A.; Shone, Alison; Stanford, Deborah; Gibbons, Peter; Davies, Jill; Vivas, Livia; Charnaud, Sarah; Bongard, Emily; Hall, Charlotte; Rimmer, Karen; Lozanom, Sonia; Jesus, Maria; Gargallo, Domingo; Ward, Stephen A.; O'Neill, Paul M.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 7 p. 2170 - 2177 Title/Abstract Full Text View citing articles Show Details
F1
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2007/100670 A1, 2007 ; Title/Abstract Full Text Show Details
30a
Audouze, Karine; Nielsen, Elsebet stergaard; Olsen, Gunnar M.; Ahring, Philip; Jorgensen, Tino Dyhring; Peters, Dan; Liljefors, Tommy; Balle, Thomas
Journal of Medicinal Chemistry, 2006 , vol. 49, # 11 p. 3159 - 3171 Title/Abstract Full Text View citing articles Show Details
14
Krunic, Aleksej; Mariappan, S. V. Santhana; Reith, Marteen E. A.; Dunn III, William J.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 24 p. 5488 - 5493 Title/Abstract Full Text View citing articles Show Details
7
Marco, Jose L.; Ingate; Chinchon
Tetrahedron, 1999 , vol. 55, # 24 p. 7625 - 7644 Title/Abstract Full Text View citing articles Show Details
Cheng, Jie; Xu, Liang; Stevens, Edwin D.; Trudell, Mark L.; Izenwasser, Sari; Wade, Dean
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 4 p. 569 - 574 Title/Abstract Full Text View citing articles Show Details
Gilbert, Adam M.; Coleman, Thomas; Kodah, Jason; Mewshaw, Richard E.; Scerni, Rosemary; Schechter, Lee E.; Smith, Deborah L.; Andree, Terrance H.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 21 p. 5281 - 5284 Title/Abstract Full Text View citing articles Show Details
5
Ripper, Justin A.; Tiekink, Edward R.T.; Scammells, Peter J.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 443 - 445 Title/Abstract Full Text View citing articles Show Details
Gilbert, Adam M.; Stack, Gary P.; Nilakantan, Ramaswamy; Kodah, Jason; Tran, Megan; Scerni, Rosemary; Shi, Xiaojie; Smith, Deborah L.; Andree, Terrance H.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 515 - 518 Title/Abstract Full Text View citing articles Show Details
Label
Reference
5b
Bei, Xiaohong; Hagemeyer, Alfred; Volpe, Anthony; Saxton, Robert; Turner, Howard; Guram, Anil S.
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8626 - 8633 Title/Abstract Full Text View citing articles Show Details
2
Drandarov, K.; Mu, L. J.; Bisson, W.; Kessler, L.; Schubiger, P. A.; Westera, G.
Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, p. S180 - S180 Title/Abstract Full Text Show Details
6
Klumpp, Douglas A.; Garza, Manuel; Jones, Andre; Mendoza, Saray
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6702 - 6705 Title/Abstract Full Text View citing articles Show Details
Thomas, James B.; Atkinson, Robert N.; Rothman, Richard B.; Burgess, Jason P.; Mascarella, S. Wayne; Dersch, Christina M.; Xu, Heng; Carroll, F. Ivy
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 11 p. 1281 - 1284 Title/Abstract Full Text View citing articles Show Details
Nicolaou; Montagnon; Baran; Zhong
Journal of the American Chemical Society, 2002 , vol. 124, # 10 p. 2245 - 2258 Title/Abstract Full Text View citing articles Show Details
Lu, Zhijian; Tata, James R.; Cheng, Kang; Wei, Liente; Chan, Wanda W.-S.; Butler, Bridget; Schleim, Klaus D.; Jacks, Thomas M.; Hickey, Gerard; Patchett, Arthur A.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1817 - 1820 Title/Abstract Full Text View citing articles Show Details
Zou, Mu-Fa; Kopajtic, Theresa; Katz, Jonathan L.; Newman, Amy Hauck
Journal of Medicinal Chemistry, 2003 , vol. 46, # 14 p. 2908 - 2916 Title/Abstract Full Text View citing articles Show Details
3
Cheng, Jie; Moore, Zakhia; Stevens, Edwin D.; Trudell, Mark L.
Journal of Organic Chemistry, 2002 , vol. 67, # 15 p. 5433 - 5436 Title/Abstract Full Text View citing articles Show Details
Bradley, Amy L.; Izenwasser, Sari; Wade, Dean; Cararas, Shaine; Trudell, Mark L.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 4 p. 629 - 632 Title/Abstract Full Text View citing articles Show Details
Allegretti, Marcello; Anacardio, Roberto; Cesta, M. Candida; Curti, Roberto; Mantovanini, Marco; Nano, Giuseppe; Topai, Alessandra; Zampella, Giuseppe
Organic Process Research and Development, 2003 , vol. 7, # 2 p. 209 - 213 Title/Abstract Full Text View citing articles Show Details
11
Belostotskii, Anatoly M.; Gottlieb, Hugo E.; Aped, Pinchas
Chemistry - A European Journal, 2002 , vol. 8, # 13 p. 3016 - 3026 Title/Abstract Full Text View citing articles Show Details
14a
Harling; Harrington; Thompson
Synthetic Communications, 2001 , vol. 31, # 5 p. 787 - 797 Title/Abstract Full Text View citing articles Show Details
1, R = Me
Jung; Park; Kim; Lee; Choi
Synthetic Communications, 2001 , vol. 31, # 21 p. 3255 - 3263 Title/Abstract Full Text View citing articles Show Details
byprod. to 2a, Scheme 2
Node, Manabu; Nakamura, Soichi; Nakamura, Daisaku; Katoh, Takahiro; Nishide, Kiyoharu
Tetrahedron Letters, 1999 , vol. 40, # 29 p. 5357 - 5360 Title/Abstract Full Text View citing articles Show Details
10
Tavasli, Mustafa; O'Hagan, David; Batsanov, Andrei S.; Foxon, Graham R.; Halliwell, Robert F.; Howard, Judith A. K.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 23 p. 3455 - 3461 Title/Abstract Full Text View citing articles Show Details
Patent-Specific Data (5)
Related Markush Structure (RN)
Location in Patent
Reference
Page/Page column
Takeda Pharmaceutical Company Limited; TOMITA, Naoki; KAJII, Shigeo; CARY, Douglas Robert; TOMITA, Daisuke; IMAMURA, Shinichi; TSUCHIDA, Ken; MATSUDA, Satoru; HARA, Ryujiro
Patent: EP2743256 A1, 2014 ; Title/Abstract Full Text Show Details
11526187
NEUROSEARCH A/S
Patent: WO2006/108790 A1, 2006 ; Title/Abstract Full Text Show Details
11537299
Bayer CropScience GmbH
Patent: EP1236727 A1, 2002 ; Title/Abstract Full Text Show Details
19818476
Pfizer Products Inc.
Patent: EP1178048 A1, 2002 ; Title/Abstract Full Text Show Details
19820689
Sankyo Company Limited
Patent: EP1243589 A1, 2002 ; Title/Abstract Full Text Show Details
Related Structure (2) Related Structure
Reference
Konformation in Loesung.
Bishop et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 74 Full Text View citing articles Show Details
Constitution.
Willstaetter
Chemische Berichte, 1898 , vol. 31, p. 1543 Chemische Berichte, 1901 , vol. 34, p. 137 Full Text View citing articles Show Details
Derivative (10) Comment (Derivative)
Reference
quart. Ammoniumjodid: B.: aus Verb.II, CH3I; F:266grad
Sato,T. et al.
Bulletin of the Chemical Society of Japan, 1971 , vol. 44, p. 1708 - 1709 Full Text View citing articles Show Details
Pikrat: F:218-220grad
O'Donovan; Keogh
Journal of the Chemical Society [Section] C: Organic, 1969 , p. 223,226 Full Text Show Details
(+-)-Oxim: F:114grad
Singh; Razdan
Indian Journal of Chemistry, 1968 , vol. 6, p. 568 Full Text Show Details
Semicarbazon: F:205grad(Zers.)
Wallace and Tiernan Inc.
Patent: GB1065684 , 1967 ; Chem.Abstr., 1967 , vol. 67, # 54139 Full Text Show Details
Pikrat C8H13NO*C6H3N3O7: F:220grad
Schmidt et al.
Journal of Pharmaceutical Sciences, 1967 , vol. 56, p. 1453,1454 Full Text Show Details
Pikrat: F:208-210grad
Romeike
Naturwissenschaften, 1966 , vol. 53, p. 38 Full Text Show Details
Hydrochlorid: Rk. m. H2/Pt/W. --> 57percent Tropin, 43percent Pseudotropin
Mistrjukow
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1965 , p. 1793 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1965 , p. 1832 Full Text Show Details
Pikrat: F:219-220grad(Zers.)
Beyerman et al.
Recueil des Travaux Chimiques des Pays-Bas, 1963 , vol. 82, p. 1199,1220 Full Text Show Details
Pikrat: F:217-219grad (unkorr.)
Shimizu et al.
Chemical and Pharmaceutical Bulletin, 1962 , vol. 10, p. 204,207 Full Text Show Details
(1S)-2-oxo-bornane-10-sulfonate (mp: 216 degree ) Further Data see Handbook
Barrowcliff; Tutin
Journal of the Chemical Society, 1909 , vol. 95, p. 1966 Full Text View citing articles Show Details
Purification (1) Reference Seiler; Werner
Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, 1964 , vol. 19, p. 572 Full Text Show Details
Beyerman et al.
Recueil des Travaux Chimiques des Pays-Bas, 1963 , vol. 82, p. 1199,1220 Full Text Show Details
Physical Data Melting Point (12) Melting Point
Solvent (Melting Point)
Comment (Melting Point)
Reference
40 - 42 °C
Katritzky et al.
Organic Magnetic Resonance, 1979 , vol. 12, p. 357,359 Full Text Show Details
41 - 43 °C
Singh et al.
Journal of Heterocyclic Chemistry, 1979 , vol. 16, p. 625,629 Full Text Show Details
Schmidt et al.
Journal of Pharmaceutical Sciences, 1967 , vol. 56, p. 1453,1454 Full Text Show Details
40 - 41 °C
Glushkov,R.G. et al.
Pharmaceutical Chemistry Journal, 1975 , vol. 9, # 12 p. 753 - 756 Khimiko-Farmatsevticheskii Zhurnal, 1975 , vol. 9, # 12 p. 6 - 9 Full Text View citing articles Show Details
41 - 42 °C
Sato,T. et al.
Bulletin of the Chemical Society of Japan, 1971 , vol. 44, p. 1708 - 1709 Full Text View citing articles Show Details
42.5 - 44 °C
Bottini; Gal
Journal of Organic Chemistry, 1971 , vol. 36, p. 1718 Full Text View citing articles Show Details
41 °C
v. Auwers
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 110 Full Text View citing articles Show Details
Singh; Razdan
Indian Journal of Chemistry, 1968 , vol. 6, p. 568 Full Text Show Details
39 - 41 °C
diethyl ether
Turner; Gearien
Journal of Pharmaceutical Sciences, 1964 , vol. 53, p. 1309,1312 Full Text Show Details
39 - 43 °C
Shimizu et al.
Chemical and Pharmaceutical Bulletin, 1962 , vol. 10, p. 204,207 Full Text Show Details
43 °C
Sekera
Annales de Chimie (Cachan, France), 1962 , vol. 7, # 13 p. 537,552,553 Full Text Show Details
40 - 42 °C
nach Sublimation im Hochvakuum.
Parker et al.
Journal of the Chemical Society, 1959 , p. 2433,2436 Full Text View citing articles Show Details
42 °C
light petroleum
Ciamician; Silber
Chemische Berichte, 1896 , vol. 29, p. 490 Gazzetta Chimica Italiana, 1896 , vol. 26 II, p. 161 Full Text View citing articles Show Details
42 °C
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 942 Chemische Berichte, 1901 , vol. 34, p. 142 Full Text View citing articles Show Details
Boiling Point (7) Boiling Point
Pressure (Boiling Point)
Reference
98 - 100 °C
12 Torr
Glushkov,R.G. et al.
Pharmaceutical Chemistry Journal, 1975 , vol. 9, # 12 p. 753 - 756 Khimiko-Farmatsevticheskii Zhurnal, 1975 , vol. 9, # 12 p. 6 - 9 Full Text View citing articles Show Details
79 - 89 °C
7 Torr
Sato,T. et al.
Bulletin of the Chemical Society of Japan, 1971 , vol. 44, p. 1708 - 1709 Full Text View citing articles Show Details
97 °C
12 Torr
Bottini; Gal
Journal of Organic Chemistry, 1971 , vol. 36, p. 1718 Full Text View citing articles Show Details
218 - 218.5 °C
v. Auwers
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 110 Full Text View citing articles Show Details
113 °C
25 Torr
Willstaetter
Chemische Berichte, 1897 , vol. 30, p. 2692 Anm. Justus Liebigs Annalen der Chemie, 1901 , vol. 317, p. 268 Full Text View citing articles Show Details
125 °C
40 Torr
Willstaetter
Chemische Berichte, 1897 , vol. 30, p. 2692 Anm. Justus Liebigs Annalen der Chemie, 1901 , vol. 317, p. 268 Full Text View citing articles Show Details
224 - 225 °C
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 398 Full Text View citing articles Show Details
714 Torr
Refractive Index (3) Refractive Index
Wavelength (Refractive Index)
Temperature (Refractive Index)
Reference
1.4598
656.3 nm
99.6 °C
v. Auwers
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 110 Full Text View citing articles Show Details
1.4621
589 nm
99.6 °C
v. Auwers
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 110 Full Text View citing articles Show Details
1.4691
486.1 nm
99.6 °C
v. Auwers
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 110 Full Text View citing articles Show Details
Density (1) Density
Reference Temperature
Measurement Temperature
Reference
0.9872 g·cm-3
4 °C
99.6 °C
v. Auwers
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 110 Full Text View citing articles Show Details
Chromatographic Data (2) Chromatographic data
Location
Reference
GC (Gas chromatography)
supporting information
Rösler, Sina; Obenauf, Johannes; Kempe, Rhett
Journal of the American Chemical Society, 2015 , vol. 137, # 25 p. 7998 - 8001 Title/Abstract Full Text View citing articles Show Details
GC (Gas chromatography)
El Bazaoui, Ahmed; Ahmed Bellimam, My; Soulaymani, Abdelmajid
Fitoterapia, 2011 , vol. 82, # 2 p. 193 - 197 Title/Abstract Full Text View citing articles Show Details
Circular Dichroism (1) Reference Hudec
Journal of the Chemical Society [Section] D: Chemical Communications, 1970 , p. 829 Full Text View citing articles Show Details
Conformation (1) Object of Investigation
Reference
Conformation
Bishop et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 74 Full Text View citing articles Show Details
Eckert; Le Fevre
Journal of the Chemical Society, 1962 , p. 3991,3993 Full Text Show Details
Hudec
Journal of the Chemical Society [Section] D: Chemical Communications, 1970 , p. 829 Full Text View citing articles Show Details
Arias, M. S.; Galvez, E.; Izquierdo, M. L.; Burgos, C.
Journal of Molecular Structure, 1986 , vol. 147, p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
Nadeln
Ciamician; Silber
Chemische Berichte, 1896 , vol. 29, p. 490 Gazzetta Chimica Italiana, 1896 , vol. 26 II, p. 161 Full Text View citing articles Show Details
Dissociation Exponent (1) Comment (Dissociation Exponent)
Reference
(pk')pK(a)
Polievktov et al.
Pharmaceutical Chemistry Journal, 1975 , vol. 9, # 6 p. 413,414,416,417 Khimiko-Farmatsevticheskii Zhurnal, 1975 , vol. 9, # 6 p. 56 Full Text View citing articles Show Details
Electrical Moment (1) Description (Electrical Moment)
Comment (Electrical Moment)
Reference
Dipole moment
ε, Bzl.:2.96 D
Eckert; Le Fevre
Journal of the Chemical Society, 1962 , p. 3991,3993 Full Text Show Details
Electrochemical Behaviour (1) Description (Electrochemical Behaviour)
Reference
Electrochemical properties
Laube et al.
Journal of Organic Chemistry, 1977 , vol. 42, p. 670,673 Full Text Show Details
Electron Binding (1) Description (Electron Binding)
Reference
Electron affinity
Martin, Hans-Dieter; Mueller, Monika; Mayer, Bernhard; Haddad, Hatim; Steigel, Alois; et al.
Chemische Berichte, 1986 , vol. 119, # 5 p. 1613 - 1626 Title/Abstract Full Text Show Details
Further Information (8) Description (Further Information)
Reference
Further information
Schmidt et al.
Journal of Pharmaceutical Sciences, 1967 , vol. 56, p. 215,219 Full Text Show Details
Further information
Blossey et al.
Tetrahedron, 1964 , vol. 20, p. 585,595 Full Text Show Details
Further information
Beyerman et al.
Recueil des Travaux Chimiques des Pays-Bas, 1963 , vol. 82, p. 1199,1220 Full Text Show Details
Further information
Shimizu et al.
Chemical and Pharmaceutical Bulletin, 1962 , vol. 10, p. 204,207 Full Text Show Details
Further information
UCHIMARU
Chemical and pharmaceutical bulletin, 1962 , vol. 10, p. 238 - 240 Title/Abstract Full Text View citing articles Show Details
Further information
Calvert; Hobson
Proceedings of the Chemical Society, London, 1962 , p. 19 Full Text Show Details
Further information
Horak; Zuman
Tetrahedron Letters, 1961 , p. 746 Full Text View citing articles Show Details
Further information
Shimizu; Uchimaru
Chemical and Pharmaceutical Bulletin, 1961 , vol. 9, p. 300,302 Full Text Show Details
Ionization Potential (2)
Ionization Potential
Method (Ionization Potential)
Comment (Ionization Potential)
Reference
8.64 eV
PE
Type: vertical. Higher potentials: 9.22 eV
Spanka, Gerhard; Rademacher, Paul
Journal of Organic Chemistry, 1986 , vol. 51, # 5 p. 592 - 596 Title/Abstract Full Text View citing articles Show Details
8.55 eV
PE
Type: vertical. Higher potentials: 9.15 eV, 11.25 eV
Martin, Hans-Dieter; Mueller, Monika; Mayer, Bernhard; Haddad, Hatim; Steigel, Alois; et al.
Chemische Berichte, 1986 , vol. 119, # 5 p. 1613 - 1626 Title/Abstract Full Text Show Details
Optics (1) Description (Optics)
Reference
Electric birefringence (Kerr effect)
Eckert; Le Fevre
Journal of the Chemical Society, 1962 , p. 3991,3993 Full Text Show Details
Spectra NMR Spectroscopy (9) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Frequency (NMR Spectroscopy)
Location
Comment (NMR Spectroscopy)
Chemical shifts
13C
chloroform-d1
Reference Pohl, Radek; Potmischil, Francisc; Dracinsky, Martin; Vanek, Vaclav; Slavetinska, Lenka; Budesinsky, Milos
Magnetic Resonance in Chemistry, 2012 , vol. 50, # 6 p. 415 - 423 Title/Abstract Full Text View citing articles Show Details
Chemical shifts Spectrum
1H
chloroform-d1
400 MHz
supporting information
Spectrum
13C
chloroform-d1
100 MHz
supporting information
Fournial, Anais; Ranaivondrambola, Tsiresy; MatheAllainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 156 Title/Abstract Full Text View citing articles Show Details Fournial, Anais; Ranaivondrambola, Tsiresy; MatheAllainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 156 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
1H
CDCl3
Basey, Keith; McGaw, Brian A.; Woolley, Jack G.
Phytochemistry (Elsevier), 1992 , vol. 31, # 12 p. 4173 4176 Title/Abstract Full Text View citing articles Show Details Arias, M. S.; Galvez, E.; Izquierdo, M. L.; Burgos, C.
Journal of Molecular Structure, 1986 , vol. 147, p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
13C
CDCl3
Basey, Keith; McGaw, Brian A.; Woolley, Jack G.
Phytochemistry (Elsevier), 1992 , vol. 31, # 12 p. 4173 4176 Title/Abstract Full Text View citing articles Show Details Arias, M. S.; Galvez, E.; Izquierdo, M. L.; Burgos, C.
Journal of Molecular Structure, 1986 , vol. 147, p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Spin-spin coupling constants
CDCl3
1H-1H
Basey, Keith; McGaw, Brian A.; Woolley, Jack G.
Phytochemistry (Elsevier), 1992 , vol. 31, # 12 p. 4173 4176 Title/Abstract Full Text View citing articles Show Details Arias, M. S.; Galvez, E.; Izquierdo, M. L.; Burgos, C.
Journal of Molecular Structure, 1986 , vol. 147, p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
CDCl3
1H-13C.
Arias, M. S.; Galvez, E.; Izquierdo, M. L.; Burgos, C.
Journal of Molecular Structure, 1986 , vol. 147, p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Spin-spin coupling constants
NMR
Jones,A.J. et al.
Canadian Journal of Chemistry, 1976 , vol. 54, p. 126 - 135 Full Text View citing articles Show Details
Kashman,Y.; Cherkez,S.
Tetrahedron, 1972 , vol. 28, p. 155 - 165 Full Text View citing articles Show Details
Fodor et al.
Tetrahedron, 1968 , vol. 24, p. 2357 Full Text View citing articles Show Details
Bishop et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 74 Full Text View citing articles Show Details
Ma; Warnhoff
Canadian Journal of Chemistry, 1965 , vol. 43, p. 1849,1852 Full Text Show Details
Katritzky et al.
Organic Magnetic Resonance, 1979 , vol. 12, p. 357,359 Full Text Show Details
Ohashi et al.
Journal of the Chemical Society [Section] D: Chemical Communications, 1971 , p. 34 Full Text Show Details
NMR with shift reagents
Chappell et al.
Journal of Pharmaceutical Sciences, 1973 , vol. 62, p. 414,418 Full Text Show Details
IR Spectroscopy (2) Description (IR Spectroscopy)
Reference
Bands
UCHIMARU
Chemical and pharmaceutical bulletin, 1962 , vol. 10, p. 238 - 240 Title/Abstract Full Text View citing articles Show Details
IR
Uchimaru
Chemical and Pharmaceutical Bulletin, 1961 , vol. 9, p. 308,310 Full Text Show Details
Mass Spectrometry (3)
Description (Mass Spectrometry)
Reference
electron impact (EI) spectrum
El Bazaoui, Ahmed; Ahmed Bellimam, My; Soulaymani, Abdelmajid
Fitoterapia, 2011 , vol. 82, # 2 p. 193 - 197 Title/Abstract Full Text View citing articles Show Details
spectrum
Yukimune; Yamagata; Hara; Yamada
Bioscience, Biotechnology and Biochemistry, 1994 , vol. 58, # 10 p. 1824 - 1827 Title/Abstract Full Text View citing articles Show Details
Kashman,Y.; Cherkez,S.
Tetrahedron, 1972 , vol. 28, p. 155 - 165 Full Text View citing articles Show Details
Blossey et al.
Tetrahedron, 1964 , vol. 20, p. 585,595 Full Text Show Details
UV/VIS Spectroscopy (2)
Description (UV/VIS Spectroscopy)
Solvent (UV/VIS Spectroscopy)
Reference
UV/VIS
Halpern; Lyons
Journal of the American Chemical Society, 1976 , vol. 98, p. 3242,3244,3245 Full Text View citing articles Show Details
Hudec
Journal of the Chemical Society [Section] D: Chemical Communications, 1970 , p. 829 Full Text View citing articles Show Details
Spectrum
H2O
Castille; Ruppol
Bulletin de la Societe de Chimie Biologique, vol. 10, p. 635 Chem. Zentralbl., 1928 , vol. 99, # II p. 622 Full Text View citing articles Show Details
Luminescence Spectroscopy (1) Description (Luminescence Spectroscopy)
Reference
Luminescence lifetime
Halpern; Lyons
Journal of the American Chemical Society, 1976 , vol. 98, p. 3242,3244,3245 Full Text View citing articles Show Details
Fluorescence Spectroscopy (1) Description (Fluorescence Spectroscopy)
Reference
Fluorescence
Halpern; Lyons
Journal of the American Chemical Society, 1976 , vol. 98, p. 3242,3244,3245 Full Text View citing articles Show Details
Other Spectroscopic Methods (1) Description (Other Spectroscopic Methods)
Reference
Photoelectron spectrum
Martin, Hans-Dieter; Mueller, Monika; Mayer, Bernhard; Haddad, Hatim; Steigel, Alois; et al.
Chemische Berichte, 1986 , vol. 119, # 5 p. 1613 - 1626 Title/Abstract Full Text Show Details
Bioactivity Pharmacological Data (18) 1 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Dr. Karl Thomae GmbH
Patent: US6344/449 B1, 2002 ; Title/Abstract Full Text Show Details
Jones,A.J. et al.
Canadian Journal of Chemistry, 1976 , vol. 54, p. 126 - 135 Full Text View citing articles Show Details
Kashman,Y.; Cherkez,S.
Tetrahedron, 1972 , vol. 28, p. 155 - 165 Full Text View citing articles Show Details
Peters, Dan; Scheel-Kruger, Jorgen; Nielsen, Elsebet Ostergaard
Patent: US2001/47028 A1, 2001 ; Title/Abstract Full Text Show Details
Sato,T. et al.
Bulletin of the Chemical Society of Japan, 1971 , vol. 44, p. 1708 - 1709 Full Text View citing articles Show Details
Neurosearch A/S
Patent: US6100275 A1, 2000 ; Title/Abstract Full Text Show Details
Devani,M.B. et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1976 , vol. 14, p. 357 - 360 Full Text View citing articles Show Details
Davies,W.A.M. et al.
Journal of the Chemical Society, 1960 , p. 3504 - 3512 Full Text View citing articles Show Details
Fishman,M.; Cruickshank,P.A.
Journal of Heterocyclic Chemistry, 1968 , vol. 5, p. 467 - 469 Full Text View citing articles Show Details
Lundbeck; H.
Patent: US5665725 A1, 1997 ; Title/Abstract Full Text Show Details
Dr. Karl Thomae GmbH
Patent: US6344449 B1, 2002 ; Title/Abstract Full Text Show Details
PROTEOTECH, INC.
Patent: WO2003/101927 A1, 2003 ; Title/Abstract Full Text Show Details
Kempter,G. et al.
Journal fuer Praktische Chemie (Leipzig), 1972 , vol. 314, # 3-4 p. 543 - 556 Full Text View citing articles Show Details
Glushkov,R.G. et al.
Pharmaceutical Chemistry Journal, 1975 , vol. 9, # 12 p. 753 - 756 Khimiko-Farmatsevticheskii Zhurnal, 1975 , vol. 9, # 12 p. 6 - 9 Full Text View citing articles Show Details
OMODT; GISVOLD
Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1960 , vol. 49, p. 153 - 158 Title/Abstract Full Text View citing articles Show Details
AnorMED, Inc.
Patent: US6750348 B1, 2004 ; Title/Abstract Full Text Show Details
AVENTIS PHARMACEUTICALS INC.
Patent: WO2004/100946 A1, 2004 ; Title/Abstract Full Text Show Details
Coats, Steve J.; Dax, Scott L.; DeCorte, Bart; Liu, Li; McDonnell, Mark; McNally, James J.
Patent: US2006/135763 A1, 2006 ; Title/Abstract Full Text Show Details
NEUROSEARCH A/S
Patent: WO2006/108789 A1, 2006 ; Title/Abstract Full Text Show Details
NEUROSEARCH A/S
Patent: WO2006/108790 A1, 2006 ; Title/Abstract Full Text Show Details
2 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2007/100670 A1, 2007 ; Title/Abstract Full Text Show Details
Maddaford, Shawn; Ramnauth, Jailall; Rakhit, Suman; Patman, Joanne; Renton, Paul; Annedi, Subhash C.
Patent: US2007/254940 A1, 2007 ; Title/Abstract Full Text Show Details
THE UNIVERSITY OF LIVERPOOL; LIVERPOOL SCHOOL OF TROPICAL MEDICINE
Patent: WO2008/38030 A2, 2008 ; Title/Abstract Full Text Show Details
Wheeler
Chemische Berichte, 1898 , vol. 31, p. 1672 Full Text View citing articles Show Details
Archer et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 5783 Full Text View citing articles Show Details
Sterling Drug Inc.
Patent: US2845427 , 1955 ; Full Text Show Details
Rosnati; Palazzo
Gazzetta Chimica Italiana, 1954 , vol. 84, p. 644,647 Full Text View citing articles Show Details
Smith, Kline and French Labor.
Patent: US2800482 , 1955 ; Full Text Show Details
Smith, Kline and French Labor.
Patent: US2800478 , 1955 ; Full Text Show Details
Sterling Drug Inc.
Patent: US2836598 , 1954 ; Full Text Show Details
Fodor et al.
Tetrahedron, 1968 , vol. 24, p. 2357 Full Text View citing articles Show Details
Findlay
Journal of Organic Chemistry, 1959 , vol. 24, p. 1540,1547 Full Text View citing articles Show Details
Keagle; Hartung
Journal of the American Chemical Society, 1946 , vol. 68, p. 1608 Full Text View citing articles Show Details
Parker et al.
Journal of the Chemical Society, 1959 , p. 2433,2436 Full Text View citing articles Show Details
Willstaetter
Chemische Berichte, 1897 , vol. 30, p. 2692 Anm. Justus Liebigs Annalen der Chemie, 1901 , vol. 317, p. 268
Full Text View citing articles Show Details
Willstaetter; Iglauer
Chemische Berichte, 1900 , vol. 33, p. 1172,1175 Full Text View citing articles Show Details
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 942 Chemische Berichte, 1901 , vol. 34, p. 142 Full Text View citing articles Show Details
v. Auwers
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 110 Full Text View citing articles Show Details
Archer et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 1227 Full Text View citing articles Show Details
Smith, Kline and French Labor.
Patent: US2800479 , 1955 ; Full Text Show Details
3 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Cope; D'Addieco
Journal of the American Chemical Society, 1951 , vol. 73, p. 3419,3423 Full Text View citing articles Show Details
Barrowcliff; Tutin
Journal of the Chemical Society, 1909 , vol. 95, p. 1966 Full Text View citing articles Show Details
Merck
Patent: DE117630 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 6, p. 1145 Full Text Show Details
Merck
Patent: DE117628 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 6, p. 1144 Full Text Show Details
Willstaetter
Patent: DE89597 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 4, p. 1213 Full Text Show Details
Merck
Patent: DE117629 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 6, p. 1145 Full Text Show Details
Merck
Patent: DE128855 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 6, p. 1150 Full Text Show Details
Merck
Patent: DE118607 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 6, p. 1146 Full Text Show Details
Willstaetter
Chemische Berichte, 1905 , vol. 38, p. 1985 Anm.1 Full Text View citing articles Show Details
Merck
Patent: DE115517 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 6, p. 1149 Full Text Show Details
Chem.Fabr.Schering
Patent: DE96362 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 5, p. 796 Full Text Show Details
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 941 Full Text View citing articles Show Details
Willstaetter; Veraguth
Chemische Berichte, 1905 , vol. 38, p. 1990 Full Text View citing articles Show Details
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 398 Full Text View citing articles Show Details
Willstaetter; Bode
Chemische Berichte, 1900 , vol. 33, p. 414 Full Text View citing articles Show Details
Willstaetter; Iglauer
Chemische Berichte, 1900 , vol. 33, p. 361 Full Text View citing articles Show Details
Willstaetter
Chemische Berichte, 1897 , vol. 30, p. 731,2681,2716 Full Text View citing articles Show Details
Willstaetter; Wolfes; Maeder
Justus Liebigs Annalen der Chemie, 1923 , vol. 434, p. 134 Full Text View citing articles Show Details
Willstaetter
Patent: DE89597 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 4, p. 1212 Full Text Show Details
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 396,947 Full Text View citing articles Show Details
4 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Willstaetter; Mueller
Chemische Berichte, 1898 , vol. 31, p. 1208 Full Text View citing articles Show Details
Ciamician; Silber
Chemische Berichte, 1896 , vol. 29, p. 490 Gazzetta Chimica Italiana, 1896 , vol. 26 II, p. 161 Full Text View citing articles Show Details
Robinson
Journal of the Chemical Society, 1917 , vol. 111, p. 766 Full Text View citing articles Show Details
Castille; Ruppol
Bulletin de la Societe de Chimie Biologique, vol. 10, p. 635 Chem. Zentralbl., 1928 , vol. 99, # II p. 622 Full Text View citing articles Show Details
Polonovski; Polonovski
Bulletin de la Societe Chimique de France, 1927 , vol. <4>41, p. 1187,1188 Full Text View citing articles Show Details
Merck
Patent: DE344031 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 13, p. 850 Full Text Show Details
Willstaetter
Patent: DE302401 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 13, p. 849 Full Text Show Details
Willstaetter; Bommer
Justus Liebigs Annalen der Chemie, 1921 , vol. 422, p. 30 Full Text View citing articles Show Details
Bishop et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 74 Full Text View citing articles Show Details
Beckett et al.
Chemistry and Industry (London, United Kingdom), 1957 , p. 663 Full Text View citing articles Show Details
Merck and Co.Inc.
Patent: US2366760 , 1942 ; Full Text Show Details
Sandoz
Patent: US2746976 , 1954 ; Full Text Show Details
Lindenmann
Helvetica Chimica Acta, 1959 , vol. 42, p. 490,494 Full Text View citing articles Show Details
Nickon; Fieser
Journal of the American Chemical Society, 1952 , vol. 74, p. 5566,5568 Full Text View citing articles Show Details
Hromatka et al.
Monatshefte fuer Chemie, 1952 , vol. 83, p. 1321,1324 Full Text View citing articles Show Details
Closs
Journal of the American Chemical Society, 1959 , vol. 81, p. 5456,5459 Full Text View citing articles Show Details
Nickon
Journal of the American Chemical Society, 1955 , vol. 77, p. 4094,4097 Full Text View citing articles Show Details
Beckett et al.
Tetrahedron, 1959 , vol. 6, p. 319,322 Full Text View citing articles Show Details
Sterling Drug Inc.
Patent: US2798874 , 1955 ; Full Text Show Details
Willstaetter; Mueller,W.
Chemische Berichte, 1898 , vol. 31, p. 2660 Full Text View citing articles Show Details
5 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Willstaetter; Bode
Chemische Berichte, 1901 , vol. 34, p. 1458,1461
Justus Liebigs Annalen der Chemie, 1903 , vol. 326, p. 50,52, 61 Full Text View citing articles Show Details
Willstaetter; Wolfes; Maeder
Justus Liebigs Annalen der Chemie, 1923 , vol. 434, p. 137 Full Text View citing articles Show Details
Merck
Patent: DE406215 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1295 Full Text Show Details
Willstaetter; Wolfes; Maeder
Justus Liebigs Annalen der Chemie, 1923 , vol. 434, p. 121 Full Text View citing articles Show Details
Willstaetter
Patent: DE302401 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1300 Full Text Show Details
Basilewskaja et al.
Zhurnal Obshchei Khimii, 1958 , vol. 28, p. 1097,1099; engl. Ausg. S. 1065, 1067 Full Text View citing articles Show Details
Passerini; Cima
Ann. Chimica farm., 1940 (Mai) 5 Full Text Show Details
Findlay
Journal of Organic Chemistry, 1957 , vol. 22, p. 1385,1388, 1392 Journal of Organic Chemistry, 1958 , vol. 23, p. 391,393 Full Text View citing articles Show Details
Schtschukina et al.
Izv. Akad. S.S.S.R. Otd. mat. estestv. Ser. chim., 1936 , p. 997,1001, 1002 Chem. Zentralbl., 1938 , vol. 109, # I p. 900 Full Text Show Details
Schtschukina et al.
Izv. Akad. S.S.S.R. Otd. mat. estestv. Ser. chim, 1936 , p. 997,1001 Chem. Zentralbl., 1938 , vol. 109, # I p. 900 Full Text Show Details
Tschesche; Snatzke
Chemische Berichte, 1957 , vol. 90, p. 579,584 Full Text View citing articles Show Details
Merck and Co. Inc.
Patent: DE1007332 , 1954 ; Full Text Show Details
Merck and Co. Inc.
Patent: US2678317 , 1953 ; Full Text Show Details
Archer et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 4194 Journal of the American Chemical Society, 1958 , vol. 80, p. 4677 Full Text View citing articles Show Details
Sterling Drug Inc.
Patent: US2836598 , 1964 ; Full Text Show Details
Sterling Drug. Inc.
Patent: US2836598 , 1954 ; Full Text Show Details
Sterling Drug. Inc.
Patent: US2845427 , 1955 ; Full Text Show Details
Sterling Drug. Inc.
Patent: US2902490 , 1957 ; Full Text Show Details
Ochiai et al.
Yakugaku Zasshi, 1937 , vol. 57, p. 407,409; dtsch. Ref. S. 87 Chem.Abstr., 1939 , p. 2142 Full Text View citing articles Show Details
Willstaetter
Chemische Berichte, 1900 , vol. 33, p. 1163 Justus Liebigs Annalen der Chemie, 1903 , vol. 326, p. 101 Full Text View citing articles Show Details
6 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Karrer; Alagil
Helvetica Chimica Acta, 1947 , vol. 30, p. 1777 Full Text View citing articles Show Details
Preobrashenski; Schtschukina; Wompe
Chemische Berichte, 1936 , vol. 69, p. 1619 Full Text View citing articles Show Details
Willstaetter
Chemische Berichte, 1898 , vol. 31, p. 1543
Chemische Berichte, 1901 , vol. 34, p. 137 Full Text View citing articles Show Details
Schoepf; Lehmann
Justus Liebigs Annalen der Chemie, 1935 , vol. 518, p. 1,25 Full Text View citing articles Show Details
Ma; Warnhoff
Canadian Journal of Chemistry, 1965 , vol. 43, p. 1849,1852 Full Text Show Details
Zirkle et al.
Journal of Organic Chemistry, 1962 , vol. 27, p. 1269,1277 Full Text Show Details
O'Donovan; Keogh
Journal of the Chemical Society [Section] C: Organic, 1969 , p. 223,226 Full Text Show Details
Seiler; Werner
Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, 1964 , vol. 19, p. 572 Full Text Show Details
Katritzky et al.
Organic Magnetic Resonance, 1979 , vol. 12, p. 357,359 Full Text Show Details
Beyerman et al.
Recueil des Travaux Chimiques des Pays-Bas, 1963 , vol. 82, p. 1199,1220 Full Text Show Details
Prasad; Wermuth
Journal of Heterocyclic Chemistry, 1968 , vol. 5, p. 559 Full Text Show Details
Hirsch
Chemische Berichte, 1967 , vol. 100, # 4 p. 1289 Full Text Show Details
Grace and Co.
Patent: US2893996 , 1957 ; Chem.Abstr., 1960 , # 612 Full Text Show Details
Singh et al.
Journal of Heterocyclic Chemistry, 1979 , vol. 16, p. 625,629 Full Text Show Details
Michaels; Zaugg
Journal of Organic Chemistry, 1960 , vol. 25, p. 637 Full Text View citing articles Show Details
Singh; Razdan
Indian Journal of Chemistry, 1968 , vol. 6, p. 568 Full Text Show Details
Sato et al.
Bulletin of the Chemical Society of Japan, 1971 , vol. 44, p. 1708 Full Text Show Details
Montzka et al.
Tetrahedron Letters, 1974 , p. 1325 Full Text View citing articles Show Details
Schmidt et al.
Journal of Pharmaceutical Sciences, 1967 , vol. 56, p. 1453,1454 Full Text Show Details
Eckert; Le Fevre
Journal of the Chemical Society, 1962 , p. 3991,3993 Full Text Show Details
7 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Horak
Collection of Czechoslovak Chemical Communications, 1963 , vol. 28, p. 1614,1616 Full Text Show Details
Turner; Gearien
Journal of Pharmaceutical Sciences, 1964 , vol. 53, p. 1309,1312 Full Text Show Details
Lyle et al.
Journal of Organic Chemistry, 1970 , vol. 35, p. 802 Full Text View citing articles Show Details
Robertson; Marion
Canadian Journal of Chemistry, 1960 , vol. 38, p. 294,296 Full Text Show Details
Shimizu et al.
Chemical and Pharmaceutical Bulletin, 1962 , vol. 10, p. 204,207 Full Text Show Details
UCHIMARU
Chemical and pharmaceutical bulletin, 1962 , vol. 10, p. 238 - 240 Title/Abstract Full Text View citing articles Show Details
Niemer; Bucherer
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1961 , vol. 326, p. 9,11 Full Text Show Details
Sekera
Annales de Chimie (Cachan, France), 1962 , vol. 7, # 13 p. 537,552,553 Full Text Show Details
Uchimaru
Chemical and Pharmaceutical Bulletin, 1961 , vol. 9, p. 308,310 Full Text Show Details
Calvert; Hobson
Proceedings of the Chemical Society, London, 1962 , p. 19 Full Text Show Details
Blossey et al.
Tetrahedron, 1964 , vol. 20, p. 585,595 Full Text Show Details
Halpern; Lyons
Journal of the American Chemical Society, 1976 , vol. 98, p. 3242,3244,3245 Full Text View citing articles Show Details
Mistrjukow; Aronowa
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1967 , p. 760,762 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1967 , p. 789 Full Text Show Details
Laube et al.
Journal of Organic Chemistry, 1977 , vol. 42, p. 670,673 Full Text Show Details
Ohashi et al.
Journal of the Chemical Society [Section] D: Chemical Communications, 1971 , p. 34 Full Text Show Details
Hayakawa; Noyori
Bulletin of the Chemical Society of Japan, 1974 , vol. 47, p. 2617 Full Text Show Details
Schmidt et al.
Journal of Pharmaceutical Sciences, 1967 , vol. 56, p. 215,219 Full Text Show Details
Reiff; Aaron
Tetrahedron Letters, 1967 , p. 2329 Full Text View citing articles Show Details
Horak; Zuman
Tetrahedron Letters, 1961 , p. 746 Full Text View citing articles Show Details
Fisch et al.
Journal of the Chemical Society [Section] D: Chemical Communications, 1970 , p. 13 Full Text Show Details
8 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Chappell et al.
Journal of Pharmaceutical Sciences, 1973 , vol. 62, p. 414,418 Full Text Show Details
Romeike
Naturwissenschaften, 1966 , vol. 53, p. 38 Full Text Show Details
Hudec
Journal of the Chemical Society [Section] D: Chemical Communications, 1970 , p. 829 Full Text View citing articles Show Details
Shimizu; Uchimaru
Chemical and Pharmaceutical Bulletin, 1961 , vol. 9, p. 300,302 Full Text Show Details
Evans; Tucker
Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics, 1976 , vol. 72, p. 1661,1665 Full Text Show Details
Bottini; Gal
Journal of Organic Chemistry, 1971 , vol. 36, p. 1718 Full Text View citing articles Show Details
Weis et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1966 , p. 1080 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1966 , p. 1120 Full Text Show Details
Polievktov et al.
Pharmaceutical Chemistry Journal, 1975 , vol. 9, # 6 p. 413,414,416,417 Khimiko-Farmatsevticheskii Zhurnal, 1975 , vol. 9, # 6 p. 56 Full Text View citing articles Show Details
Irwin; Jones
Journal of the American Chemical Society, 1976 , vol. 98, p. 8476,8477 Full Text Show Details
Wallace and Tiernan Inc.
Patent: GB1065684 , 1967 ; Chem.Abstr., 1967 , vol. 67, # 54139 Full Text Show Details
Mistrjukow
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1965 , p. 1793 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1965 , p. 1832 Full Text Show Details
Hobson; McCluskey
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 2015 Full Text Show Details
Shapiro, A. B.; Belostotskii, A. M.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989 , vol. 38, # 3.2 p. 593 - 596 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989 , # 3 p. 667 - 671 Title/Abstract Full Text View citing articles Show Details
Lansbury, Peter T.; Spagnuolo, Ciro J.; Grimm, Erich L.
Tetrahedron Letters, 1990 , vol. 31, # 28 p. 3965 - 3968 Title/Abstract Full Text View citing articles Show Details
Mattson, Ronald J.; Pham, Kahnie M.; Leuck, David J.; Cowen, Kenneth A.
Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2552 - 2554 Title/Abstract Full Text View citing articles Show Details
Santamaria, J.; Kaddachi, M. T.; Rigaudy, J.
Tetrahedron Letters, 1990 , vol. 31, # 33 p. 4735 - 4738 Title/Abstract Full Text View citing articles Show Details
Landgrebe, Mary E.; Leete, Edward
Phytochemistry (Elsevier), 1990 , vol. 29, # 8 p. 2521 - 2524 Title/Abstract Full Text View citing articles Show Details
Simola, Liisa Kaarina; Parviainen, Riita; Martinsen, Aarne; Huhtikangas, Aare; Jokela, Reija; Lounasmaa, Mauri
Phytochemistry (Elsevier), 1990 , vol. 29, # 11 p. 3517 - 3523 Title/Abstract Full Text View citing articles Show Details
Macor, John E.; Newman, Michael E.; Ryan, Kevin
Tetrahedron Letters, 1989 , vol. 30, # 19 p. 2509 - 2512 Title/Abstract Full Text View citing articles Show Details
Moriarty, Robert M.; Prakash, Om; Karalis, Pauline; Prakash, Indra
Tetrahedron Letters, 1984 , vol. 25, # 42 p. 4745 - 4748 Title/Abstract Full Text View citing articles Show Details
9 of 18
10 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Lounasmaa, Mauri; Langenskioeld, Tord; Holmberg, Carl
Tetrahedron Letters, 1981 , vol. 22, # 51 p. 5179 - 5180 Title/Abstract Full Text View citing articles Show Details
Shvo, Youval; Kaufman, Edwin D.
Journal of Organic Chemistry, 1982 , vol. 47, # 11 p. 2190 - 2192 Title/Abstract Full Text View citing articles Show Details
Macor, John E.; Ryan, Kevin; Newman, Michael E.
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4785 - 4795 Title/Abstract Full Text View citing articles Show Details
Carroll, F. Ivy; Coleman, Michael L.; Lewin, Anita H.
Journal of Organic Chemistry, 1982 , vol. 47, # 1 p. 13 - 19 Title/Abstract Full Text Show Details
Sauerwein, Martina; Ishimaru, Kanji; Shimomura, Koichiro
Phytochemistry (Elsevier), 1991 , vol. 30, # 9 p. 2977 - 2978 Title/Abstract Full Text View citing articles Show Details
Parr, Adrian J.; Walton, Nick J.; Bensalem, Smail; McCabe, Peter H.; Routledge, William
Phytochemistry (Elsevier), 1991 , vol. 30, # 8 p. 2607 - 2609 Title/Abstract Full Text View citing articles Show Details
Santamaria, J.; Ouchabane, R.; Rigaudy, J.
Tetrahedron Letters, 1989 , vol. 30, # 30 p. 3977 - 3980 Title/Abstract Full Text View citing articles Show Details
Santamaria, J.; Ouchabane, R.; Rigaudy, J.
Tetrahedron Letters, 1989 , vol. 30, # 22 p. 2927 - 2928 Title/Abstract Full Text View citing articles Show Details
Swain; Baker; Kneen; Herbert; Moseley; Saunders; Seward; Stevenson; Beer; Stanton; Watling; Ball
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1019 - 1031 Title/Abstract Full Text View citing articles Show Details
Murr, Brown L.; Parkhill, Billy J.; Nickon, Alex
Tetrahedron, 1992 , vol. 48, # 23 p. 4845 - 4862 Title/Abstract Full Text View citing articles Show Details
Burgos, C.; Galvez, E.; Izquierdo, M. L.; Airas, M. S.; Matesanz, E.; et al.
Journal of Molecular Structure, 1992 , vol. 269, # 1-2 p. 123 - 140 Title/Abstract Full Text View citing articles Show Details
Spanka, Gerhard; Rademacher, Paul
Journal of Organic Chemistry, 1986 , vol. 51, # 5 p. 592 - 596 Title/Abstract Full Text View citing articles Show Details
Basey, Keith; McGaw, Brian A.; Woolley, Jack G.
Phytochemistry (Elsevier), 1992 , vol. 31, # 12 p. 4173 - 4176 Title/Abstract Full Text View citing articles Show Details
Mewshaw; Sherrill; Mathew; Kaiser; Bailey; Karbon
Journal of Medicinal Chemistry, 1993 , vol. 36, # 3 p. 343 - 352 Title/Abstract Full Text View citing articles Show Details
Burgos; Galvez; Izquierdo; Arias; Sanz-Aparicio; Fonseca; Lopez
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 7 p. 1821 - 1827 Title/Abstract Full Text View citing articles Show Details
Baasov, Timor; Sheves, Mordechai
Journal of the American Chemical Society, 1985 , vol. 107, # 25 p. 7524 - 7533 Title/Abstract Full Text View citing articles Show Details
Moriarty, Robert M.; Prakash, Om; Vavilikolanu, Pushra R.
Synthetic Communications, 1986 , vol. 16, # 10 p. 1247 - 1254 Title/Abstract Full Text Show Details
Simola, Liisa Kaarina; Martinsen, Aarne; Huhtikangas, Aarre; Jokela, Reija; Lounasmaa, Mauri
Acta Chemica Scandinavica, 1989 , vol. 43, # 7 p. 702 - 705 Title/Abstract Full Text Show Details
Gutkowska, Bozenna; Kmiotek, Ryszard
Polish Journal of Chemistry, 1980 , vol. 54, # 7/8 p. 1579 - 1583 Title/Abstract Full Text Show Details
Galvez, E.; Martinez, M.; Trigo, G. G.; Florencio, F.; Vilches, J.; et al.
Journal of Molecular Structure, 1981 , vol. 75, p. 241 - 254 Title/Abstract Full Text View citing articles Show Details
Comment
Bioactivities present
(Pharmacological Data)
11 of 18
Reference
Sarel, Shalom; Dykman, Edmund
Heterocycles, 1981 , vol. 15, # 2 p. 719 - 734 Title/Abstract Full Text Show Details
Arias, M. S.; Galvez, E.; Izquierdo, M. L.; Burgos, C.
Journal of Molecular Structure, 1986 , vol. 147, p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Martin, Hans-Dieter; Mueller, Monika; Mayer, Bernhard; Haddad, Hatim; Steigel, Alois; et al.
Chemische Berichte, 1986 , vol. 119, # 5 p. 1613 - 1626 Title/Abstract Full Text Show Details
Sauter, Fritz; Stanetty, Peter; Blaschke, Alfred
Journal of Chemical Research, Miniprint, 1981 , # 4 p. 1027 - 1042 Title/Abstract Full Text Show Details
Burgos, C.; Izquierdo, M. L.; Arias, M. S.; Galvez, E.; Matesanz, E.; et al.
Journal of Molecular Structure, 1993 , vol. 301, p. 95 - 106 Title/Abstract Full Text View citing articles Show Details
Wysocka, Waleria
Heterocycles, 1982 , vol. 19, # 1 p. 1 - 5 Title/Abstract Full Text Show Details
Majewski, Marek; Lazny, Ryszard
Tetrahedron Letters, 1994 , vol. 35, # 22 p. 3653 - 3656 Title/Abstract Full Text View citing articles Show Details
Bartholomew; Smith; Darcy; Trudgill; Hopper
Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 1 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details
Cignarella, G.; Villa, S.; Barlocco, D.
European Journal of Medicinal Chemistry, 1994 , vol. 29, # 1 p. 115 - 120 Title/Abstract Full Text View citing articles Show Details
Leete, Edward; Kim, Sung Hoon
Journal of the Chemical Society, Chemical Communications, 1989 , # 24 p. 1899 - 1900 Title/Abstract Full Text View citing articles Show Details
Grunewald; Sall; Monn
Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 433 - 444 Title/Abstract Full Text View citing articles Show Details
Yukimune; Yamagata; Hara; Yamada
Bioscience, Biotechnology and Biochemistry, 1994 , vol. 58, # 10 p. 1824 - 1827 Title/Abstract Full Text View citing articles Show Details
Meltzer, Peter C.; Liang, Anna. Y.; Madras, Bertha. K.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 13 p. 2001 - 2010 Title/Abstract Full Text View citing articles Show Details
Newman, Amy Hauck; Allen, Andrew C.; Izenwasser, Sari; Katz, Jonathan L.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 15 p. 2258 - 2261 Title/Abstract Full Text View citing articles Show Details
Workentin, Mark S.; Johnston, Linda J.; Wayner, Danial D. M.; Parker, Vernon D.
Journal of the American Chemical Society, 1994 , vol. 116, # 18 p. 8279 - 8287 Title/Abstract Full Text View citing articles Show Details
Newcombe; Simpkins
Journal of the Chemical Society - Series Chemical Communications, 1995 , # 8 p. 831 - 832 Title/Abstract Full Text View citing articles Show Details
Kostochka, L. M.; Lezina, V. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1994 , vol. 30, # 3 p. 335 - 339 Khimiya Geterotsiklicheskikh Soedinenii, 1994 , # 3 p. 381 - 386 Title/Abstract Full Text View citing articles Show Details
Majewski, Marek; Lazny, Ryszard; Nowak, Pawel
Tetrahedron Letters, 1995 , vol. 36, # 31 p. 5465 - 5468 Title/Abstract Full Text View citing articles Show Details
Perregaard; Moltzen; Meier; Sanchez
Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1998 - 2008 Title/Abstract Full Text View citing articles Show Details
Doelling, Wolfgang; Hellrung, Bernhard; Siebel, Hans-Martin
Phosphorus, Sulfur and Silicon and the Related Elements, 1994 , vol. 96, # 1-4 p. 409 - 412 Title/Abstract Full Text Show Details
Comment (Pharmacological Data)
Bioactivities present
Reference
Kato; Ito; Nishino; Yamakuni; Takasugi
Chemical and pharmaceutical bulletin, 1995 , vol. 43, # 8 p. 1351 - 1357 Title/Abstract Full Text View citing articles Show Details
Xu, Rui; Chu, Guohua; Bai, Donglu
Tetrahedron Letters, 1996 , vol. 37, # 9 p. 1463 - 1466 Title/Abstract Full Text View citing articles Show Details
Newman, Amy Hauck; Kline, Richard H.; Allen, Andrew C.; Izenwasser, Sari; George, Clifford; Katz, Jonathan L.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 20 p. 3933 - 3940 Title/Abstract Full Text View citing articles Show Details
Kostochka, L. M.; Skoldinov, A. P.; Lezina, V. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995 , vol. 31, # 2 p. 153 - 156 Khimiya Geterotsiklicheskikh Soedinenii, 1995 , # 2 p. 179 - 183 Title/Abstract Full Text View citing articles Show Details
Suemune, Hiroshi; Uchida, Jun; Sakai, Kiyoshi
Heterocycles, 1996 , vol. 43, # 3 p. 625 - 631 Title/Abstract Full Text View citing articles Show Details
Abdel-Magid, Ahmed F.; Carson, Kenneth G.; Harris, Bruce D.; Maryanoff, Cynthia A.; Shah, Rekha D.
Journal of Organic Chemistry, 1996 , vol. 61, # 11 p. 3849 - 3862 Title/Abstract Full Text View citing articles Show Details
McGill, John M.; Labell, Elizabeth S.; Williams, MaryAnn
Tetrahedron Letters, 1996 , vol. 37, # 23 p. 3977 - 3980 Title/Abstract Full Text View citing articles Show Details
Lai, Yen-Shi; Mendoza, Jose S.; Jagdmann Jr., G. Erik; Menaldino, David S.; Biggers, Christopher K.; Heerding, Julia M.; Wilson, Joseph W.; Hall, Steven E.; Jiang, Jack B.; Janzen, William P.; Ballas, Lawrence M.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 2 p. 226 - 235 Title/Abstract Full Text View citing articles Show Details
Majewski, Marek; Lazny, Ryszard; Ulaczyk, Agnieszka
Canadian Journal of Chemistry, 1997 , vol. 75, # 6 p. 754 - 761 Title/Abstract Full Text View citing articles Show Details
Heidempergher, Franco; Pillan, Antonio; Pinciroli, Vittorio; Vaghi, Fabrizio; Arrigoni, Claudio; Bolis, Giorgio; Caccia, Carla; Dho, Luciano; McArthur, Robert; Varasi, Mario
Journal of Medicinal Chemistry, 1997 , vol. 40, # 21 p. 3369 - 3380 Title/Abstract Full Text View citing articles Show Details
Kim, Oak K.; Hudyma, Thomas W.; Matiskella, John D.; Ueda, Yasutsugu; Bronson, Joanne J.; Mansuri, Muzammil M.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 21 p. 2753 - 2758 Title/Abstract Full Text View citing articles Show Details
Xu, Rong; Sim, Meng-Kwoon; Go, Mei-Lin
Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3220 - 3231 Title/Abstract Full Text View citing articles Show Details
Thompson, Philip E.; Steer, David L.; Aguilar, Marie-Isabel; Hearn, Milton T. W.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 19 p. 2699 - 2704 Title/Abstract Full Text View citing articles Show Details
Node, Manabu; Nakamura, Soichi; Nakamura, Daisaku; Katoh, Takahiro; Nishide, Kiyoharu
Tetrahedron Letters, 1999 , vol. 40, # 29 p. 5357 - 5360 Title/Abstract Full Text View citing articles Show Details
Marco, Jose L.; Ingate; Chinchon
Tetrahedron, 1999 , vol. 55, # 24 p. 7625 - 7644 Title/Abstract Full Text View citing articles Show Details
Ujvary, Istvan; Polgar, Laszlo; Darvas, Bela; Casida, John E.
Pesticide Science, 1995 , vol. 44, # 1 p. 96 - 102 Title/Abstract Full Text Show Details
Klumpp, Douglas A.; Garza, Manuel; Jones, Andre; Mendoza, Saray
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6702 - 6705 Title/Abstract Full Text View citing articles Show Details
Tavasli, Mustafa; O'Hagan, David; Batsanov, Andrei S.; Foxon, Graham R.; Halliwell, Robert F.; Howard, Judith A. K.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 23 p. 3455 - 3461 Title/Abstract Full Text View citing articles Show Details
Boswell, Henry D.; DraI ger, Birgit; McLauchlan, W. Russell; Portsteffen, Andreas; Robins, David J.; Robins, Richard J.; Walton, Nicholas J.
Phytochemistry, 1999 , vol. 52, # 5 p. 871 - 878 Title/Abstract Full Text View citing articles Show Details
Varlamov; Voskresenskii; Borisova; Chernyshev; Levov
Chemistry of Heterocyclic Compounds, 1999 , vol. 35, # 5 p. 613 - 616 Title/Abstract Full Text View citing articles Show Details
12 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Duran-Patron, Rosa; O'Hagan, David; Hamilton, John T.G.; Wong, Chi W.
Phytochemistry, 2000 , vol. 53, # 7 p. 777 - 784 Title/Abstract Full Text View citing articles Show Details
Wagner, Paul; Nakagawa, Yumi; Lee, Greg S.; Davis, Mark E.; Elomari, Saleh; Medrud, Ronald C.; Zones
Journal of the American Chemical Society, 2000 , vol. 122, # 2 p. 263 - 273 Title/Abstract Full Text View citing articles Show Details
Radl, Stanislav; Hezky, Petr; Hafner, Wieland; Budesinsky, Milos; Hejnova, Lucie
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 55 - 58 Title/Abstract Full Text View citing articles Show Details
Radl, Stanislav; Hafner, Wieland; Budesinsky, Milo; Hejnova, Lucie; Krejci, Ivan
Archiv der Pharmazie, 2000 , vol. 333, # 6 p. 167 - 174 Title/Abstract Full Text View citing articles Show Details
Boyd, Robert E.; Carson, John R.; Codd, Ellen E.; Gauthier, A. Diane; Neilson, Lou Anne; Zhang, Sui-Po
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 10 p. 1109 - 1111 Title/Abstract Full Text View citing articles Show Details
Thomas, James B.; Atkinson, Robert N.; Rothman, Richard B.; Burgess, Jason P.; Mascarella, S. Wayne; Dersch, Christina M.; Xu, Heng; Carroll, F. Ivy
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 11 p. 1281 - 1284 Title/Abstract Full Text View citing articles Show Details
Zhang; Rothman; Dersch; De Costa; Jacobson; Rice
Journal of Medicinal Chemistry, 2000 , vol. 43, # 25 p. 4840 - 4849 Title/Abstract Full Text View citing articles Show Details
Harling; Harrington; Thompson
Synthetic Communications, 2001 , vol. 31, # 5 p. 787 - 797 Title/Abstract Full Text View citing articles Show Details
Crawforth, James; Goodacre, Simon; Maxey, Robert; Bourrain, Sylvie; Patel, Smita; Marwood, Rosemarie; O'Connor, Desmond; Herbert, Richard; Hutson, Peter; Rowley, Michael
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2701 - 2703 Title/Abstract Full Text View citing articles Show Details
Ripper, Justin A.; Tiekink, Edward R.T.; Scammells, Peter J.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 443 - 445 Title/Abstract Full Text View citing articles Show Details
Klimova; Garcia, M. Martinez; Lopez, E. A. Vazquez; Toledano, C. Alvarez; Toscano, R. Alfredo; Ramirez, L. Ruiz
Russian Chemical Bulletin, 2001 , vol. 50, # 5 p. 895 - 900
Title/Abstract Full Text View citing articles Show Details
Lyapkalo, Ilya M.; Webel, Matthias; Reissig, Hans-Ulrich
European Journal of Organic Chemistry, 2002 , # 6 p. 1015 - 1025 Title/Abstract Full Text View citing articles Show Details
Berdini, Valerio; Cesta, Maria C; Curti, Roberto; D'Anniballe, Gaetano; Bello, Nicoletta Di; Nano, Giuseppe; Nicolini, Luca; Topai, Alessandra; Allegretti, Marcello
Tetrahedron, 2002 , vol. 58, # 28 p. 5669 - 5674 Title/Abstract Full Text View citing articles Show Details
Majewski, Marek; Wang, Fan
Tetrahedron, 2002 , vol. 58, # 23 p. 4567 - 4571 Title/Abstract Full Text View citing articles Show Details
Nicolaou; Montagnon; Baran; Zhong
Journal of the American Chemical Society, 2002 , vol. 124, # 10 p. 2245 - 2258 Title/Abstract Full Text View citing articles Show Details
Zhang; Joseph; Bowen; Flippen-Anderson; Dersch; Rothman; Jacobson; Rice
Journal of Medicinal Chemistry, 2001 , vol. 44, # 23 p. 3937 - 3945 Title/Abstract Full Text View citing articles Show Details
Belostotskii, Anatoly M.; Gottlieb, Hugo E.; Aped, Pinchas
Chemistry - A European Journal, 2002 , vol. 8, # 13 p. 3016 - 3026 Title/Abstract Full Text View citing articles Show Details
Cheng, Jie; Moore, Zakhia; Stevens, Edwin D.; Trudell, Mark L.
Journal of Organic Chemistry, 2002 , vol. 67, # 15 p. 5433 - 5436 Title/Abstract Full Text View citing articles Show Details
Kostochka; Chernyakova
Pharmaceutical Chemistry Journal, 2000 , vol. 34, # 12 p. 635 - 637 Title/Abstract Full Text View citing articles Show Details
Hunt, Julianne A.; Kallashi, Florida; Ruzek, Rowena D.; Sinclair, Peter J.; Ita, Ida; McCormick, Sherrie X.; Pivnichny, James V.; Hop, Cornelis E. C. A.; Kumar, Sanjeev; Wang, Zhen; O'Keefe, Stephen J.; O'Neill, Edward A.; Porter, Gene; Thompson, James E.; Woods, Andrea; Zaller, Dennis M.; Doherty, James B.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 467 - 470 Title/Abstract Full Text View citing articles Show Details
13 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Bradley, Amy L.; Izenwasser, Sari; Wade, Dean; Cararas, Shaine; Trudell, Mark L.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 4 p. 629 - 632 Title/Abstract Full Text View citing articles Show Details
Lu, Zhijian; Tata, James R.; Cheng, Kang; Wei, Liente; Chan, Wanda W.-S.; Butler, Bridget; Schleim, Klaus D.; Jacks, Thomas M.; Hickey, Gerard; Patchett, Arthur A.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1817 - 1820 Title/Abstract Full Text View citing articles Show Details
Zou, Mu-Fa; Kopajtic, Theresa; Katz, Jonathan L.; Newman, Amy Hauck
Journal of Medicinal Chemistry, 2003 , vol. 46, # 14 p. 2908 - 2916 Title/Abstract Full Text View citing articles Show Details
Gong, Leyi; Hogg, J. Heather; Collier, James; Wilhelm, Robert S.; Soderberg, Carol
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 20 p. 3597 - 3600 Title/Abstract Full Text View citing articles Show Details
Abbiati, Giorgio; Arcadi, Antonio; Bianchi, Gabriele; Di Giuseppe, Sabrina; Marinelli, Fabio; Rossi, Elisabetta
Journal of Organic Chemistry, 2003 , vol. 68, # 18 p. 6959 - 6966 Title/Abstract Full Text View citing articles Show Details
Lazny, Ryszard; Nodzewska, Aneta; Wolosewicz, Karol
Synthesis, 2003 , # 18 p. 2858 - 2864 Title/Abstract Full Text View citing articles Show Details
Gilbert, Adam M.; Stack, Gary P.; Nilakantan, Ramaswamy; Kodah, Jason; Tran, Megan; Scerni, Rosemary; Shi, Xiaojie; Smith, Deborah L.; Andree, Terrance H.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 515 - 518 Title/Abstract Full Text View citing articles Show Details
Badio, Barbara; Garraffo, H. Martin; Plummer, Carlton V.; Padgett, William L.; Daly, John W.
European Journal of Pharmacology, 1997 , vol. 321, # 2 p. 189 - 194 Title/Abstract Full Text View citing articles Show Details
Carson, John R.; Coats, Steven J.; Codd, Ellen E.; Dax, Scott L.; Lee, Jung; Martinez, Rebecca P.; Neilson, Lou Anne; Pitis, Philip M.; Zhang, Sui-Po
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2109 - 2112 Title/Abstract Full Text View citing articles Show Details
Cheng, Jie; Xu, Liang; Stevens, Edwin D.; Trudell, Mark L.; Izenwasser, Sari; Wade, Dean
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 4 p. 569 - 574 Title/Abstract Full Text View citing articles Show Details
Lyapkalo, Ilya M.; Hoegermeier, Jens; Reissig, Hans-Ulrich
Tetrahedron, 2004 , vol. 60, # 35 p. 7721 - 7729 Title/Abstract Full Text View citing articles Show Details
Rodriguez-Franco, Maria Isabel; Dorronsoro, Isabel; Castro, Ana; Martinez, Ana; Badia, Albert; Banos, Josep E.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 10 p. 2263 - 2268 Title/Abstract Full Text View citing articles Show Details
Zheng, Guangrong; Dwoskin, Linda P.; Crooks, Peter A.
Synthetic Communications, 2004 , vol. 34, # 11 p. 1931 - 1942 Title/Abstract Full Text View citing articles Show Details
Gilbert, Adam M.; Coleman, Thomas; Kodah, Jason; Mewshaw, Richard E.; Scerni, Rosemary; Schechter, Lee E.; Smith, Deborah L.; Andree, Terrance H.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 21 p. 5281 - 5284 Title/Abstract Full Text View citing articles Show Details
Bei, Xiaohong; Hagemeyer, Alfred; Volpe, Anthony; Saxton, Robert; Turner, Howard; Guram, Anil S.
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8626 - 8633 Title/Abstract Full Text View citing articles Show Details
Drandarov, K.; Mu, L. J.; Bisson, W.; Kessler, L.; Schubiger, P. A.; Westera, G.
Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, p. S180 - S180 Title/Abstract Full Text Show Details
Krunic, Aleksej; Mariappan, S. V. Santhana; Reith, Marteen E. A.; Dunn III, William J.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 24 p. 5488 - 5493 Title/Abstract Full Text View citing articles Show Details
Mattsson, Cecilia; Sonesson, Clas; Sandahl, Anna; Greiner, Hartmut E.; Gassen, Michael; Plaschke, Joerg; Leibrock, Joachim; Boettcher, Henning
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 19 p. 4230 - 4234 Title/Abstract Full Text View citing articles Show Details
Li, Ang; Kindelin, Patrick J.; Klumpp, Douglas A.
Organic Letters, 2006 , vol. 8, # 6 p. 1233 - 1236 Title/Abstract Full Text View citing articles Show Details
Vatsadze; Kostochka; Lezina; Vinokurov; Zyk
Russian Chemical Bulletin, 2004 , vol. 53, # 12 p. 2805 - 2809 Title/Abstract Full Text View citing articles Show Details
14 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Audouze, Karine; Nielsen, Elsebet stergaard; Olsen, Gunnar M.; Ahring, Philip; Jorgensen, Tino Dyhring; Peters, Dan; Liljefors, Tommy; Balle, Thomas
Journal of Medicinal Chemistry, 2006 , vol. 49, # 11 p. 3159 - 3171 Title/Abstract Full Text View citing articles Show Details
Pham-Huu, Duy-Phong; Deschamps, Jeffrey R.; Liu, Shanghao; Madras, Bertha K.; Meltzer, Peter C.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 2 p. 1067 - 1082 Title/Abstract Full Text View citing articles Show Details
Jung; Park; Kim; Lee; Choi
Synthetic Communications, 2001 , vol. 31, # 21 p. 3255 - 3263 Title/Abstract Full Text View citing articles Show Details
Fleischhauer; Beckert; Guenther; Goerls
Synthesis, 2006 , # 17 p. 2885 - 2890 Title/Abstract Full Text View citing articles Show Details
Willand, Nicolas; Folleas, Benoit; Boutillon, Christophe; Verbraeken, Liesbeth; Gesquiere, Jean-Claude; Tartar, Andre; Deprez, Benoit
Tetrahedron Letters, 2007 , vol. 48, # 29 p. 5007 - 5011 Title/Abstract Full Text View citing articles Show Details
Kuethe, Jeffrey T.; Varon, Jack; Childers, Karla G.
Tetrahedron, 2007 , vol. 63, # 46 p. 11489 - 11502 Title/Abstract Full Text View citing articles Show Details
Bayer CropScience GmbH
Patent: EP1236727 A1, 2002 ; Title/Abstract Full Text Show Details
NeuroSearch A/S
Patent: US6645977 B1, 2003 ; Title/Abstract Full Text Show Details
Watson, Robert J.; Allen, Daniel R.; Birch, Helen L.; Chapman, Gayle A.; Galvin, Frances C.; Jopling, Louise A.; Knight, Roland L.; Meier, Dorica; Oliver, Kathryn; Meissner, Johannes W.G.; Owen, David A.; Thomas, Elizabeth J.; Tremayne, Neil; Williams, Sophie C.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 1 p. 147 - 151 Title/Abstract Full Text View citing articles Show Details
SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/118724 A1, 2008 ; Title/Abstract Full Text Show Details
Bristol-Myers Squibb Company
Patent: US2008/227769 A1, 2008 ; Title/Abstract Full Text Show Details
Calogeropoulou, Theodora; Angelou, Panagiotis; Detsi, Anastasia; Fragiadaki, Irene; Scoulica, Effie
Journal of Medicinal Chemistry, 2008 , vol. 51, # 4 p. 897 - 908 Title/Abstract Full Text View citing articles Show Details
Ellis, Gemma L.; Amewu, Richard; Sabbani, Sunil; Stocks, Paul A.; Shone, Alison; Stanford, Deborah; Gibbons, Peter; Davies, Jill; Vivas, Livia; Charnaud, Sarah; Bongard, Emily; Hall, Charlotte; Rimmer, Karen; Lozanom, Sonia; Jesus, Maria; Gargallo, Domingo; Ward, Stephen A.; O'Neill, Paul M.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 7 p. 2170 - 2177 Title/Abstract Full Text View citing articles Show Details
Mai, Antonello; Cheng, Donghang; Bedford, Mark T.; Valente, Sergio; Nebbioso, Angela; Perrone, Andrea; Brosch, Gerald; Sbardella, Gianluca; De Bellis, Floriana; Miceli, Marco; Altucci, Lucia
Journal of Medicinal Chemistry, 2008 , vol. 51, # 7 p. 2279 - 2290 Title/Abstract Full Text View citing articles Show Details
Brock University
Patent: US2009/5565 A1, 2009 ; Title/Abstract Full Text Show Details
Fei, Zhongbo; Wu, Quanbing; Zhang, Fei; Cao, Yudong; Liu, Chuanqin; Shieh, Wen-Chung; Xue, Song; McKenna, Joe; Prasad, Kapa; Prashad, Mahavir; Baeschlin, Daniel; Namoto, Kenji
Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 9016 - 9021 Title/Abstract Full Text View citing articles Show Details
Pati, Hari N.; Das, Umashankar; Das, Swagatika; Bandy, Brian; De Clercq, Erik; Balzarini, Jan; Kawase, Masami; Sakagami, Hiroshi; Quail, J. Wilson; Stables, James P.; Dimmock, Jonathan R.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 1 p. 54 - 62 Title/Abstract Full Text View citing articles Show Details
Kolesi-Ska, Beata; Kami-Ski, Zbigniew J.
Acta Poloniae Pharmaceutica - Drug Research, 2008 , vol. 65, # 6 p. 749 - 751 Title/Abstract Full Text View citing articles Show Details
Bezencon, Olivier; Bur, Daniel; Corminboeuf, Olivier; Dube, Daniel; Grisostomi, Corinna; MacDonald, Dwight; McKay, Dan; Powell, David; Remen, Lubos; Richard-Bildstein, Sylvia; Scheigetz, John; Therien, Michel; Weller, Thomas
Patent: US2009/176823 A1, 2009 ; Title/Abstract Full Text Show Details
Glaxo Group Limited
Patent: US2009/197871 A1, 2009 ; Title/Abstract Full Text Show Details
15 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Paul, Noel M.; Taylor, Michelle; Kumar, Rakesh; Deschamps, Jeffrey R.; Luedtke, Robert R.; Newman, Amy Hauck
Journal of Medicinal Chemistry, 2008 , vol. 51, # 19 p. 6095 - 6109 Title/Abstract Full Text View citing articles Show Details
MEDIVATION TECHNOLOGIES,INC.
Patent: WO2009/120720 A1, 2009 ; Title/Abstract Full Text Show Details
Wijtmans, Maikel; Verzijl, Dennis; van Dam, Cindy M.E.; Bosch, Leontien; Smit, Martine J.; Leurs, Rob; de Esch, Iwan J.P.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 8 p. 2252 - 2257 Title/Abstract Full Text View citing articles Show Details
Holland, Jason P.; Jones, Michael W.; Bonnitcha, Paul D.; Lewis, Jason S.; Dilworth, Jonathan R.
New Journal of Chemistry, 2009 , vol. 33, # 9 p. 1845 - 1852 Title/Abstract Full Text View citing articles Show Details
Yang, Shu-Wei; Ho, Ginny; Tulshian, Deen; Greenlee, William J.; Tan, Zheng; Zhang, Hongtao; Smith-Torhan, April; Fawzi, Ahmad; Anthes, John; Lu, Sherry; Varty, Geoffrey; Fernandez, Xiomara; McLeod, Robbie L.; Hey, John
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 9 p. 2482 - 2486 Title/Abstract Full Text View citing articles Show Details
Ho, Ginny D.; Anthes, John; Bercovici, Ana; Caldwell, John P.; Cheng, Kuo-Chi; Cui, Xiaoming; Fawzi, Ahmad; Fernandez, Xiomara; Greenlee, William J.; Hey, John; Korfmacher, Walter; Lu, Sherry X.; McLeod, Robbie L.; Ng, Fay; Torhan, April Smith; Tan, Zheng; Tulshian, Deen; Varty, Geoffrey B.; Xu, Xiaoying; Zhang, Hongtao
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 9 p. 2519 - 2523 Title/Abstract Full Text View citing articles Show Details
Pfizer Products Inc.
Patent: EP1178048 A1, 2002 ; Title/Abstract Full Text Show Details
Sankyo Company Limited
Patent: EP1243589 A1, 2002 ; Title/Abstract Full Text Show Details
NEUROSCIENZE PHARMANESS S.C.A.R.L.
Patent: US2010/29622 A1, 2010 ; Title/Abstract Full Text Show Details
Neuroscienze Pharmaness S.C. A R.L.
Patent: EP2149575 A1, 2010 ; Title/Abstract Full Text Show Details
Fournial, Anais; Ranaivondrambola, Tsiresy; Mathe-Allainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 - 156 Title/Abstract Full Text View citing articles Show Details
ABBOTT LABORATORIES; SCHRIMPF, Michael R.; LEE, Chih-Hung; LI, Tao; GFESSER, Gregory A.; MORTELL, Kathleen H.; FAGHIH, Ramin; NERSESIAN, Diana L.; SIPPY, Kevin B.; BUNNELLE, William H.; SCANIO, Marc; SHI, Lei; GOPALAKRISHNAN, Murali; DONNELLY-ROBERTS, Diana; HU, Min
Patent: WO2010/36998 A2, 2010 ; Title/Abstract Full Text Show Details
Kaur, Harneet; Izenwasser, Sari; Verma, Abha; Wade, Dean; Housman, Amy; Stevens, Edwin D.; Mobley, David L.; Trudell, Mark L.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 24 p. 6865 - 6868 Title/Abstract Full Text View citing articles Show Details
Holloway; Parisot; Novello; Watson; Armstrong; Thompson; Street; Baell
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 6 p. 1816 - 1818 Title/Abstract Full Text View citing articles Show Details
NEUROSEARCH A/S; PETERS, Dan; JONES, David, Spencer; NIELSEN, Elsebet, OEstergaard
Patent: WO2010/57848 A1, 2010 ; Title/Abstract Full Text Show Details
Yadav, Babasaheb; Taurin, Sebastien; Rosengren, Rhonda J.; Schumacher, Marc; Diederich, Marc; Somers-Edgar, Tiffany J.; Larsen, Lesley
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 18 p. 6701 - 6707 Title/Abstract Full Text View citing articles Show Details
VERTEX PHARMACEUTICALS, INCORPORATED
Patent: WO2006/23852 A2, 2006 ; Title/Abstract Full Text Show Details
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2006/58303 A2, 2006 ; Title/Abstract Full Text Show Details
NEUROSEARCH A/S
Patent: WO2006/64031 A1, 2006 ; Title/Abstract Full Text Show Details
BANYU PHARMACEUTICAL CO.,LTD.; KAMEDA, Minoru; KOBAYASHI, Kensuke; NAKAMA, Chisato; ANDO, Makoto; SATO, Nagaaki
Patent: WO2010/126163 A1, 2010 ; Title/Abstract Full Text Show Details
16 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
ACTELION PHARMACEUTICALS LTD
Patent: WO2006/92268 A1, 2006 ; Title/Abstract Full Text Show Details
BANYU PHARMACEUTICAL CO., LTD.
Patent: EP1726590 A1, 2006 ; Title/Abstract Full Text Show Details
GLAXO GROUP LIMITED
Patent: WO2007/16650 A2, 2007 ; Title/Abstract Full Text Show Details
SANOFI-AVENTIS
Patent: US2007/149562 A1, 2007 ; Title/Abstract Full Text Show Details
ACTELION PHARMACEUTICALS LTD
Patent: WO2007/88514 A1, 2007 ; Title/Abstract Full Text Show Details
ALBANY MOLECULAR RESEARCH, INC.
Patent: US2011/3737 A1, 2011 ; Title/Abstract Full Text Show Details
LUPIN LIMITED; ROY, Bhairab, Nath; KAMBOJ, Rajender, Kumar; GEORGE, Shaji, K.; VENUGOPAL, Spinvin, C.; SHANMUGVADIVELU, Muthu, Kumaran; SINHA, Neelima
Patent: WO2011/18796 A1, 2011 ; Title/Abstract Full Text Show Details
NEUROSCIENZE PHARMANESS S.C. A.R.L.
Patent: US2011/152238 A1, 2011 ; Title/Abstract Full Text Show Details
ABBOTT LABORATORIES
Patent: US2011/152306 A1, 2011 ; Title/Abstract Full Text Show Details
Renton, Paul; Speed, Joanne; Maddaford, Shawn; Annedi, Subhash C.; Ramnauth, Jailall; Rakhit, Suman; Andrews, John
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5301 - 5304 Title/Abstract Full Text View citing articles Show Details
NEUROSEARCH A/S
Patent: US2011/263640 A1, 2011 ; Title/Abstract Full Text Show Details
Slowinski, Tomasz; Stefanowicz, Jacek; Dawidowski, MacIej; Kleps, Jerzy; Czuczwar, Stanislaw; Andres-Mach, Marta; Luszczki, Jarogniew J.; Nowak, Gabriel; Stachowicz, Katarzyna; Szewczyk, Bernadeta; Slawinska, Anna; Mazurek, Aleksander P.; Mazurek, Andrzej; Plucinski, Franciszek; Wolska, Irena; Herold, Franciszek
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4474 - 4488 Title/Abstract Full Text View citing articles Show Details
Naeja Pharmaceutical Inc.
Patent: US2011/288063 A1, 2011 ; Title/Abstract Full Text Show Details
Cararas, Shaine A.; Izenwasser, Sari; Wade, Dean; Housman, Amy; Verma, Abha; Lomenzo, Stacey A.; Trudell, Mark L.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 24 p. 7551 - 7558 Title/Abstract Full Text View citing articles Show Details
Jirschitzka, Jan; Schmidt, Gregor W.; Reichelt, Michael; Schneider, Bernd; Gershenzon, Jonathan; D'Auria, John Charles
Proceedings of the National Academy of Sciences of the United States of America, 2012 , vol. 109, # 26 p. 10304 - 10309 Title/Abstract Full Text View citing articles Show Details
Pohl, Radek; Potmischil, Francisc; Dracinsky, Martin; Vanek, Vaclav; Slavetinska, Lenka; Budesinsky, Milos
Magnetic Resonance in Chemistry, 2012 , vol. 50, # 6 p. 415 - 423 Title/Abstract Full Text View citing articles Show Details
LUPIN LIMITED
Patent: US2012/203004 A1, 2012 ; Title/Abstract Full Text Show Details
Lazny, Ryszard; Sienkiewicz, Michal; Olenski, Tomasz; Urbanczyk-Lipkowska, Zofia; Kalicki, Przemyslaw
Tetrahedron, 2012 , vol. 68, # 39 p. 8236 - 8244 Title/Abstract Full Text View citing articles Show Details
El Bazaoui, Ahmed; Ahmed Bellimam, My; Soulaymani, Abdelmajid
Fitoterapia, 2011 , vol. 82, # 2 p. 193 - 197 Title/Abstract Full Text View citing articles Show Details
Li, Yuanming; Jia, Fan; Li, Zhiping
Chemistry - A European Journal, 2013 , vol. 19, # 1 p. 82 - 86 Title/Abstract Full Text View citing articles Show Details
17 of 18
Comment (Pharmacological Data)
Bioactivities present
Reference
Narayanan, Nara
Patent: US2013/137873 A1, 2013 ; Title/Abstract Full Text Show Details
Yu, Yang; Yang, Xiao-Fei; Xu, Chao-Fan; Ding, Chang-Hua; Hou, Xue-Long
Organic Letters, 2013 , vol. 15, # 15 p. 3880 - 3883 Title/Abstract Full Text View citing articles Show Details
Allegretti, Marcello; Anacardio, Roberto; Cesta, M. Candida; Curti, Roberto; Mantovanini, Marco; Nano, Giuseppe; Topai, Alessandra; Zampella, Giuseppe
Organic Process Research and Development, 2003 , vol. 7, # 2 p. 209 - 213 Title/Abstract Full Text View citing articles Show Details
Chaudhary, Anurag; Sharma; Bhardwaj, Gautam; Jain, Vaibhav; Bharatam; Shrivastav, Birendra; Roy
Medicinal Chemistry Research, 2013 , vol. 22, # 12 p. 5654 - 5669 Title/Abstract Full Text View citing articles Show Details
Takeda Pharmaceutical Company Limited; TOMITA, Naoki; KAJII, Shigeo; CARY, Douglas Robert; TOMITA, Daisuke; IMAMURA, Shinichi; TSUCHIDA, Ken; MATSUDA, Satoru; HARA, Ryujiro
Patent: EP2743256 A1, 2014 ; Title/Abstract Full Text Show Details
Riken; ISHIKAWA Fumihiko; SAITO Yoriko; HASHIZUME Yoshinobu; KODA Yasuko; YUKI Hitomi
Patent: EP2878601 A1, 2015 ; Title/Abstract Full Text Show Details
Rösler, Sina; Obenauf, Johannes; Kempe, Rhett
Journal of the American Chemical Society, 2015 , vol. 137, # 25 p. 7998 - 8001 Title/Abstract Full Text View citing articles Show Details
ACADIA Pharmaceuticals Inc.; ANDERSSON, Carl-Magnus A.; CROSTON, Glenn; HANSEN, Eva Louise; ULDAM, Allan Kjaersgaard
Patent: US2015/259291 A1, 2015 ; Title/Abstract Full Text Show Details
Alonso, Francisco; Arroyo, Adrián; Martín-García, Iris; Moglie, Yanina
Advanced Synthesis and Catalysis, 2015 , vol. 357, # 16-17 p. 3549 - 3561 Title/Abstract Full Text View citing articles Show Details
Prevet, Hugues; Flipo, Marion; Roussel, Pascal; Deprez, Benoit; Willand, Nicolas
Tetrahedron Letters, 2016 , vol. 57, # 26 p. 2888 - 2894 Title/Abstract Full Text View citing articles Show Details
Stefanowicz, Jacek; Słowiński, Tomasz; Wróbel, Martyna Zofia; Herold, Franciszek; Gomółka, Anna Edyta; Wesołowska, Anna; Jastrzębska-Więsek, Magdalena; Partyka, Anna; Andres-Mach, Marta; Czuczwar, Stanisław Jerzy; Łuszczki, Jarogniew Jacek; Zagaja, Mirosław; Siwek, Agata; Nowak, Gabriel; Żołnierek, Maria; Bączek, Tomasz; Ulenberg, Szymon; Belka, Mariusz; Turło, Jadwiga
Bioorganic and Medicinal Chemistry, 2016 , vol. 24, # 18 p. 3994 - 4007 Title/Abstract Full Text View citing articles Show Details
East China University of Science and Technology; Song, Gonghua; Lu, Qing; Xu, Jun; Sun, Lu; Wang, Jiayi; Xu, Beiling; Cui, Jialu; Zhou, Xiaoying; Zhu, Jipeng; Zheng, Yiting; Fu, Xiaogen
Patent: CN105294674 A, 2016 ; Title/Abstract Full Text Show Details
Kunming Institute of Botany, Chinese Academy of Sciences; Chen, Jijun; Yin, Xiujuan; Geng, Changan; Zhang, Xuemei
Patent: CN105924436 A, 2016 ; Title/Abstract Full Text Show Details
Lazny, Ryszard; Ratkiewicz, Artur; Brzezinski, Krzysztof; Nodzewska, Aneta; Sidorowicz, Katarzyna
Journal of Chemistry, 2016 , vol. 2016, art. no. 4674901 Title/Abstract Full Text View citing articles Show Details
Beijing Sineva Co.,Ltd; Li, Xinli
Patent: CN106543178 A, 2017 ; Title/Abstract Full Text Show Details
18 of 18
Comment (Pharmacological Data)
no stimulation of alkaloid production in Atropa belladonna
Reference
Simola, Liisa Kaarina; Parviainen, Riita; Martinsen, Aarne; Huhtikangas, Aare; Jokela, Reija; Lounasmaa, Mauri
Phytochemistry (Elsevier), 1990 , vol. 29, # 11 p. 3517 - 3523 Title/Abstract Full Text View citing articles Show Details
Other Data Abiotic Degradation, Hydrolysis (1) 1 of 1
Type (Abiotic Degradation, Hydrolysis)
reduction
Concentration (Abiotic Degradation, Hydrolysis)
2.5 - 5 mmol/l
pH-Value (Abiotic Degradation, Hydrolysis)
6.4
Degradation Product (Abiotic Degradation, Hydrolysis)
tropine
Method, Remarks (Abiotic Degradation, Hydrolysis)
tropinone reductase I and II from the Brugmansia candida x aurea hybrid and Datura stramonium, transformed with Agrobacterium rhizogenes; reductase activity was determined spectrophotometrically
Reference
Boswell, Henry D.; DraI ger, Birgit; McLauchlan, W. Russell; Portsteffen, Andreas; Robins, David J.; Robins, Richard J.; Walton, Nicholas J.
Phytochemistry, 1999 , vol. 52, # 5 p. 871 - 878 Title/Abstract Full Text View citing articles Show Details
Isolation from Natural Product (3) Isolation from Natural Product
Reference
Hyoscyamus albus (roots transformed with Agrobacterium rhizogenes strain MAFF 03-01724)
Sauerwein, Martina; Ishimaru, Kanji; Shimomura, Koichiro
Phytochemistry (Elsevier), 1991 , vol. 30, # 9 p. 2977 2978 Title/Abstract Full Text View citing articles Show Details
das von Romeike, Naturwiss. 52 <1965> 619 neben Hygrin aus Nicandra physaloides (L.) isolierte Alkaloid wurde als Tropinon erkannt
Romeike
Naturwissenschaften, 1966 , vol. 53, p. 38 Full Text Show Details
Nicandra physaloides (L.)
Romeike
Naturwissenschaften, 1966 , vol. 53, p. 38 Full Text Show Details
Chemical Name: tropinone
2
Reaxys Registry Number: 1524439
CAS Registry Number: 532-24-1 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: CH3N(CH2)4(CH)2CO Molecular Weight: 139.197 InChI Key: QQXLDOJGLXJCSE-KNVOCYPGSA-N
11 prep out of 429 reactions.
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropinone, 3-tropanone, (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-one, (8-methyl-8-azabicyclo[3.2.1]octan-3-one), 8-methyl-8-azabicyclo[3.2.1]octan-3-one, 8-methyl-8-azabicyclo[3.2.1]octan-3-one, N-methylnortropinone Identification Substance Label (24) Label
Reference
1
Zou, Mu-Fa; Agoston, Gregory E.; Belov, Yuri; Kopajtic, Theresa; Katz, Jonathan L.; Newman, Amy Hauck
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 9 p. 1249 - 1252 Title/Abstract Full Text View citing articles Show Details
Lazny, Ryszard; Nodzewska, Aneta; Sidorowicz, Katarzyna; Kalicki, Przemyslaw
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 1877 - 1883 Title/Abstract Full Text View citing articles Show Details
Lazny, Ryszard; Wolosewicz, Karol; Ratkiewicz, Artur; Pioro, Damian; Stocki, Marcin
Tetrahedron, 2014 , vol. 70, # 3 p. 597 - 607
Identification Physical Data (11) Spectra (18) Bioactivity (2) Other Data (5)
112
Title/Abstract Full Text View citing articles Show Details
Nodzewska, Aneta; Bokina, Agnieszka; Romanowska, Katarzyna; Lazny, Ryszard
RSC Advances, 2014 , vol. 4, # 56 p. 29668 - 29681 Title/Abstract Full Text View citing articles Show Details
Ramachandran, Sreekanth; Hameed P., Shahul; Srivastava, Abhishek; Shanbhag, Gajanan; Morayya, Sapna; Rautela, Nikhil; Awasthy, Disha; Kavanagh, Stefan; Bharath, Sowmya; Reddy, Jitendar; Panduga, Vijender; Prabhakar; Saralaya, Ramanatha; Nanduri, Robert; Raichurkar, Anandkumar; Menasinakai, Sreenivasaiah; Achar, Vijayashree; Jiménez-Díaz, María Belén; Martínez, María Santos; Angulo-Barturen, Iñigo; Ferrer, Santiago; Sanz, Laura María; Gamo, Francisco Javier; Duffy, Sandra; Avery, Vicky M.; Waterson, David; Lee, Marcus C. S.; Coburn-Flynn, Olivia; Fidock, David A.; Iyer, Pravin S.; Narayanan, Shridhar; Hosagrahara, Vinayak; Sambandamurthy, Vasan K.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 15 p. 6642 - 6652 Title/Abstract Full Text View citing articles Show Details
Mabied, Ahmed F.; Girgis, Adel S.; Shalaby, El-Sayed M.; George, Riham F.; El-Gendy, Bahaa El-Dien M.; Baselious, Fady N.
Journal of Heterocyclic Chemistry, 2016 , vol. 53, # 4 p. 1074 - 1080 Title/Abstract Full Text View citing articles Show Details
2
Chiou, Wen-Hua; Chiang, Yu-Min; Chen, Guei-Tang
Tetrahedron Asymmetry, 2014 , vol. 25, # 1 p. 92 - 97 Title/Abstract Full Text View citing articles Show Details
Yin, Xiu-Juan; Geng, Chang-An; Huang, Xiao-Yan; Chen, Hao; Ma, Yun-Bao; Chen, Xing-Long; Sun, Chang-Li; Yang, Tong-Hua; Zhou, Jun; Zhang, XueMei; Chen, Ji-Jun
RSC Advances, 2016 , vol. 6, # 51 p. 45059 - 45063 Title/Abstract Full Text View citing articles Show Details
1f
Ma, Lina; Li, Yuanming; Li, Zhiping
Science China Chemistry, 2015 , vol. 58, # 8 p. 1310 - 1315 Title/Abstract Full Text View citing articles Show Details
Orejarena Pacheco, Julio Cesar; Lipp, Alexander; Nauth, Alexander M.; Acke, Fabian; Dietz, Jule-Philipp; Opatz, Till
Chemistry - A European Journal, 2016 , vol. 22, # 15 p. 5409 - 5415 Title/Abstract Full Text View citing articles Show Details
11
Ismail, Nasser S. M.; George, Riham F.; Serya, Rabah A. T.; Baselious, Fady N.; El-Manawaty, May; Shalaby, Elsayed M.; Girgis, Adel S.
RSC Advances, 2016 , vol. 6, # 104 p. 101911 - 101923 Title/Abstract Full Text View citing articles Show Details
3h
Tsarev, Vasily N.; Morioka, Yuna; Caner, Joaquim; Wang, Qing; Ushimaru, Richiro; Kudo, Akihiko; Naka, Hiroshi; Saito, Susumu
Organic Letters, 2015 , vol. 17, # 10 p. 2530 - 2533 Title/Abstract Full Text View citing articles Show Details
6j
Wagner, Alexander; Ofial, Armin R.
Journal of Organic Chemistry, 2015 , vol. 80, # 5 p. 2848 - 2854 Title/Abstract Full Text View citing articles Show Details
4
Nodzewska, Aneta; Sidorowicz, Katarzyna; Sienkiewicz, Michal
Synthesis (Germany), 2014 , vol. 46, # 11 art. no. SS-2013-T0827-OP, p. 1475 - 1480 Title/Abstract Full Text View citing articles Show Details
16
Vlahovic, Sandra; Schaedel, Nicole; Tussetschlaeger, Stefan; Laschat, Sabine
European Journal of Organic Chemistry, 2013 , # 8 p. 1580 - 1590 Title/Abstract Full Text View citing articles Show Details
2h
Li, Yuanming; Ma, Lina; Jia, Fan; Li, Zhiping
Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5638 - 5646 Title/Abstract Full Text View citing articles Show Details
13
Dallanoce, Clelia; Matera, Carlo; De Amici, Marco; De Micheli, Carlo; Canovi, Mara; Mennini, Tiziana; Gobbi, Marco
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6344 - 6355,12 Title/Abstract Full Text Show Details
Dallanoce, Clelia; Canovi, Mara; Matera, Carlo; Mennini, Tiziana; De Amici, Marco; Gobbi, Marco; De Micheli, Carlo
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6344 - 6355 Title/Abstract Full Text View citing articles Show Details
6
Chen, Zhi-Hua; Tian, Jin-Miao; Chen, Zhi-Min; Tu, Yong-Qiang
Chemistry - An Asian Journal, 2012 , vol. 7, # 10 p. 2199 - 2202,4 Title/Abstract Full Text Show Details
1px
Neuroscienze Pharmaness S.C. A R.L.
Patent: EP2338889 A1, 2011 ; Title/Abstract Full Text Show Details
3
Lee, Jae Chol; Lee, Kwangho; Cha, Jin Kun
Journal of Organic Chemistry, 2000 , vol. 65, # 15 p. 4773 - 4775 Title/Abstract Full Text View citing articles Show Details
Zhang, Xing; Abraham, Philip; Mascarell, S. Wayne; Flippen-Anderson, Judith; Deschamps, Jeffrey R.; Carrolla, F.Ivy
Arkivoc, 2010 , vol. 2010, # 4 p. 96 - 103 Title/Abstract Full Text View citing articles Show Details
EA
PURDUE PHARMA L.P.; SHIONOGI and CO., LTD.; YAO, Jiangchao; WHITEHEAD, John, W., F.; TSUNO, Naoki; FUCHINO, Kouki
Patent: WO2010/10458 A1, 2010 ;
Title/Abstract Full Text Show Details
DA; EA
PURDUE PHARMA L.P.; SHIONOGI and CO., LTD.
Patent: WO2009/27820 A2, 2009 ; Title/Abstract Full Text Show Details
SYNGENTA PARTICIPATIONS AG; SYNGENTA LIMITED
Patent: WO2009/7115 A1, 2009 ;
A
Title/Abstract Full Text Show Details
PURDUE PHARMA L.P.; SHIONOGI and CO., LTD.
Patent: WO2008/89201 A2, 2008 ;
IA
Title/Abstract Full Text Show Details
31
Ablordeppey, Seth Y.; Altundas, Ramazan; Bricker, Barbara; Zhu, Xue Y.; Suresh Kumar, Eyunni V.K.; Jackson, Tanise; Khan, Abdul; Roth, Bryan L.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 15 p. 7291 - 7301 Title/Abstract Full Text View citing articles Show Details
F1
Makings, Lewis R.; Blanco, Miguel Garcia-Guzman; Hurley, Dennis J.; Drutu, Ioana; Raffai, Gabriel; Bergeron, Daniele M.; Nakatani, Akiko; Termin, Andreas P.; Silina, Alina
Patent: US2008/15179 A1, 2008 ; Title/Abstract Full Text Show Details
Majewski, Marek; Ulaczyk-Lesanko, Agnieszka; Wang, Fan
Canadian Journal of Chemistry, 2006 , vol. 84, # 2 p. 257 - 268 Title/Abstract Full Text View citing articles Show Details
39
Label
Reference
5
Appell, Michael; Dunn III, William J.; Reith, Maarten E.A.; Miller, Larry; Flippen-Anderson, Judith L.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 5 p. 1197 - 1206 Title/Abstract Full Text View citing articles Show Details
8
Bradley, Amy L; Izenwasser, Sari; Wade, Dean; Klein-Stevens, Cheryl; Zhu, Naijue; Trudell, Mark L
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 17 p. 2387 - 2390 Title/Abstract Full Text View citing articles Show Details
n=2, R=CH3
Yang; Whirrett; Wu; Wheeler; Childers; Mach
Journal of Labelled Compounds and Radiopharmaceuticals, 1999 , vol. 42, # SUPPL. 1 p. S684-S686 Title/Abstract Full Text View citing articles Show Details
15d
Majewski, Marek; Ulaczyk, Agnieszka; Wang, Fan
Tetrahedron Letters, 1999 , vol. 40, # 50 p. 8755 - 8758 Title/Abstract Full Text View citing articles Show Details
Derivative (1) Comment (Derivative)
Reference
Pikrat: F:212grad(Zers.)
Evans et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 2017 Full Text Show Details
Physical Data Melting Point (3) Melting Point
Reference
41 - 42 °C
Chiou, Wen-Hua; Chiang, Yu-Min; Chen, Guei-Tang
Tetrahedron Asymmetry, 2014 , vol. 25, # 1 p. 92 - 97 Title/Abstract Full Text View citing articles Show Details
40 °C
Laha, Joydev K.
Chemistry of Natural Compounds, 2010 , vol. 46, # 2 p. 254 - 256 Title/Abstract Full Text View citing articles Show Details
42 °C
Bick,I.R.C. et al.
Australian Journal of Chemistry, 1979 , vol. 32, p. 1827 - 1840
Full Text View citing articles Show Details
Boiling Point (1) Boiling Point
Pressure (Boiling Point)
105 110 °C
11.2511 Torr
Location
Reference
Page/Page column 4
MYLAN LABORATORIES LTD.; GORE, Vinayak; JOSHI, Rajesh; TRIPATHI, Anil Kumar; JADHAV, Madhav; BHANDARI, Shreyas
Patent: WO2014/102829 A1, 2014 ; Title/Abstract Full Text Show Details
Chromatographic Data (2) Chromatographic data
Reference
UPLC (Ultra performance liquid chromatography)
Nardin, Tiziana; Barnaba, Chiara; Larcher, Roberto; Piasentier, Edi
Journal of Mass Spectrometry, 2016 , p. 729 - 741 Title/Abstract Full Text View citing articles Show Details
TLC (Thin layer chromatography)
Chiou, Wen-Hua; Chiang, Yu-Min; Chen, Guei-Tang
Tetrahedron Asymmetry, 2014 , vol. 25, # 1 p. 92 - 97 Title/Abstract Full Text View citing articles Show Details
Conformation (1) Object of Investigation
Reference
Conformation
Lazny, Ryszard; Ratkiewicz, Artur; Nodzewska, Aneta; Wynimko, Anna; Siergiejczyk, Leszek
Tetrahedron, 2012 , vol. 68, # 31 p. 6158 - 6163 Title/Abstract Full Text View citing articles Show Details
Crystal Property Description (3) Colour & Other Properties
Location
Reference
yellow
supporting information
Tsarev, Vasily N.; Morioka, Yuna; Caner, Joaquim; Wang, Qing; Ushimaru, Richiro; Kudo, Akihiko; Naka, Hiroshi; Saito, Susumu
Organic Letters, 2015 , vol. 17, # 10 p. 2530 - 2533 Title/Abstract Full Text View citing articles Show Details
white
Chiou, Wen-Hua; Chiang, Yu-Min; Chen, Guei-Tang
Tetrahedron Asymmetry, 2014 , vol. 25, # 1 p. 92 - 97 Title/Abstract Full Text View citing articles Show Details
brown
Laha, Joydev K.
Chemistry of Natural Compounds, 2010 , vol. 46, # 2 p. 254 - 256 Title/Abstract Full Text View citing articles Show Details
Partition octan-1-ol/water (MCS) (1) log POW 0.65
Reference Yin, Xiu-Juan; Geng, Chang-An; Huang, Xiao-Yan; Chen, Hao; Ma, Yun-Bao; Chen, Xing-Long; Sun, Chang-Li; Yang, Tong-Hua; Zhou, Jun; Zhang, Xue-Mei; Chen, Ji-Jun
RSC Advances, 2016 , vol. 6, # 51 p. 45059 - 45063 Title/Abstract Full Text View citing articles Show Details
Spectra NMR Spectroscopy (12) Description (NMR Spectroscopy) Chemical shifts Spectrum
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Temperature (NMR Spectroscopy)
Frequency (NMR Spectroscopy)
1H
chloroform-d1
24.3 °C
600 MHz
Location
Reference
supporting information
Tsarev, Vasily N.; Morioka, Yuna; Caner, Joaquim; Wang, Qing; Ushimaru, Richiro; Kudo, Akihiko; Naka, Hiroshi; Saito, Susumu
Organic Letters, 2015 , vol. 17, # 10 p. 2530 - 2533 Title/Abstract Full Text View citing articles Show Details
Chemical shifts Spectrum
13C
chloroform-d1
25.9 °C
150 MHz
supporting information
Tsarev, Vasily N.; Morioka, Yuna; Caner, Joaquim; Wang, Qing; Ushimaru, Richiro; Kudo, Akihiko; Naka, Hiroshi; Saito, Susumu
Organic Letters, 2015 , vol. 17, # 10 p. 2530 - 2533 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
1H
chloroform-d1
25 °C
400 MHz
Chiou, Wen-Hua; Chiang, Yu-Min; Chen, Guei-Tang
Tetrahedron Asymmetry, 2014 , vol. 25, # 1 p. 92 - 97 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
13C
chloroform-d1
25 °C
100 MHz
Chiou, Wen-Hua; Chiang, Yu-Min; Chen, Guei-Tang
Tetrahedron Asymmetry, 2014 , vol. 25, # 1 p. 92 - 97 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
13C
d(4)-methanol
-90 °C
100 MHz
Lazny, Ryszard; Ratkiewicz, Artur; Nodzewska, Aneta; Wynimko, Anna; Siergiejczyk, Leszek
Tetrahedron, 2012 , vol. 68, # 31 p. 6158 - 6163 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
13C
d(4)-methanol
25 °C
100 MHz
Lazny, Ryszard; Ratkiewicz, Artur; Nodzewska, Aneta; Wynimko, Anna; Siergiejczyk, Leszek
Tetrahedron, 2012 , vol. 68, # 31 p. 6158 - 6163 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
1H
chloroform-d1
200 MHz
Laha, Joydev K.
Chemistry of Natural Compounds, 2010 , vol. 46, # 2 p. 254 256 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
13C
chloroform-d1
50 MHz
Laha, Joydev K.
Chemistry of Natural Compounds, 2010 , vol. 46, # 2 p. 254 256 Title/Abstract Full Text View citing articles Show Details
Spectrum
1H
CDCl3
Gaevskaya; Koz'min; Tolkachev; Miroshnikov
Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 2 p. 98 101 Title/Abstract Full Text View citing articles Show Details
Spectrum
15N
various solvent(s)
Ford, Yves-Yannick; Ratcliffe, R. George; Robins, Richard J.
Phytochemistry, 1996 , vol. 43, # 1 p. 115 - 120 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
15N
various solvent(s)
Ford, Yves-Yannick; Ratcliffe, R. George; Robins, Richard J.
Phytochemistry, 1996 , vol. 43, # 1 p. 115 - 120 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
1H
CDCl3
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 2626 Title/Abstract Full Text Show Details
IR Spectroscopy (2) Description (IR Spectroscopy)
Solvent (IR Spectroscopy)
Bands
Bands
Location
Reference
neat liquid
supporting information
Tsarev, Vasily N.; Morioka, Yuna; Caner, Joaquim; Wang, Qing; Ushimaru, Richiro; Kudo, Akihiko; Naka, Hiroshi; Saito, Susumu
Organic Letters, 2015 , vol. 17, # 10 p. 2530 - 2533 Title/Abstract Full Text View citing articles Show Details
chloroform
Laha, Joydev K.
Chemistry of Natural Compounds, 2010 , vol. 46, # 2 p. 254 - 256 Title/Abstract Full Text View citing articles Show Details
Mass Spectrometry (4) Description (Mass Spectrometry) IT (ion trap) electrospray ionisation (ESI)
Location
Reference
Nardin, Tiziana; Barnaba, Chiara; Larcher, Roberto; Piasentier, Edi
Journal of Mass Spectrometry, 2016 , p. 729 - 741
tandem mass spectrometry spectrum
Title/Abstract Full Text View citing articles Show Details
high resolution mass spectrometry (HRMS) electron impact (EI) spectrum
supporting information
Tsarev, Vasily N.; Morioka, Yuna; Caner, Joaquim; Wang, Qing; Ushimaru, Richiro; Kudo, Akihiko; Naka, Hiroshi; Saito, Susumu
Organic Letters, 2015 , vol. 17, # 10 p. 2530 - 2533 Title/Abstract Full Text View citing articles Show Details
high resolution mass spectrometry (HRMS) electron impact (EI) spectrum
Chiou, Wen-Hua; Chiang, Yu-Min; Chen, Guei-Tang
Tetrahedron Asymmetry, 2014 , vol. 25, # 1 p. 92 - 97 Title/Abstract Full Text View citing articles Show Details
spectrum
Gaevskaya; Koz'min; Tolkachev; Miroshnikov
Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 2 p. 98 - 101 Title/Abstract Full Text View citing articles Show Details
Bioactivity Pharmacological Data (2) 1 of 2
2 of 2
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Yin, Xiu-Juan; Geng, Chang-An; Huang, Xiao-Yan; Chen, Hao; Ma, Yun-Bao; Chen, Xing-Long; Sun, Chang-Li; Yang, TongHua; Zhou, Jun; Zhang, Xue-Mei; Chen, Ji-Jun
RSC Advances, 2016 , vol. 6, # 51 p. 45059 - 45063 Title/Abstract Full Text View citing articles Show Details
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Gentil, Emmanuel; Kosieradzka, Katarzyna; Le Faouder, Pauline; Molini, Roland; Gentil, Emmanuel; Lebreton, Jacques; Robins, Richard J.
Title/Abstract Full Text View citing articles Show Details
Other Data Isolation from Natural Product (5) Isolation from Natural Product
Reference
Erythroxylum lucidum
Brachet, Anne; Munoz, Orlando; Gupta, Mahabir; Veuthey, Jean-Luc; Christen, Philippe
Phytochemistry, 1997 , vol. 46, # 8 p. 1439 - 1442 Title/Abstract Full Text View citing articles Show Details
grass of Atropa belladonna
Gaevskaya; Koz'min; Tolkachev; Miroshnikov
Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 2 p. 98 - 101 Title/Abstract Full Text View citing articles Show Details
Erythroxylum monogynum
Christen; Roberts; Phillipson; Evans
Phytochemistry, 1995 , vol. 38, # 4 p. 1053 - 1056 Title/Abstract Full Text View citing articles Show Details
Erythroxylum zambesiacum
Christen, Philippe; Roberts, Margaret F.; Phillipson, J. David; Evans, William C.
Phytochemistry (Elsevier), 1993 , vol. 34, # 4 p. 1147 - 1152 Title/Abstract Full Text View citing articles Show Details
Wurzelextrakt von Cyphomandra betacea Sendt
Evans et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 2017 Full Text Show Details
Chemical Name: tropinone hydrochloride
3
Reaxys Registry Number: 3912908
CAS Registry Number: 4827-85-4 Type of Substance: heterocyclic Molecular Formula: C8H13NO*ClH Linear Structure Formula: C8H13NO*ClH Molecular Weight: 175.658 InChI Key: HUGYQXFQBHWMQD-UHFFFAOYSA-N
0 prep out of 14 reactions.
Identification Physical Data (3) Spectra (3)
9
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropinone hydrochloride, tropan-3-one; hydrochloride, Tropan-3-on; Hydrochlorid, 8-methyl-8-azabicyclo[3.2.1]octan-3-one hydrochloride Identification Substance Label (1) Label
Reference
II*HCl
Trigo; Martinez; Galvez
Journal of pharmaceutical sciences, 1981 , vol. 70, # 1 p. 87 - 89 Title/Abstract Full Text View citing articles Show Details
Physical Data Melting Point (2) Melting Point
Solvent (Melting Point)
Comment (Melting Point)
Reference
188 - 190 °C
ethanol diethyl ether
Decomp.
Lindenmann
Helvetica Chimica Acta, 1959 , vol. 42, p. 490,494 Full Text View citing articles Show Details
188 - 189 °C
ethanol
Decomp.
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 398 Full Text View citing articles Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
glaenzende Prismen
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 398 Full Text View citing articles Show Details
Spectra NMR Spectroscopy (3) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Comment (NMR Spectroscopy)
Chemical shifts
1H
dimethylsulfoxide
Trigo; Martinez; Galvez
Journal of pharmaceutical sciences, 1981 , vol. 70, # 1 p. 87 - 89 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
13C
D2O
Trigo; Martinez; Galvez
Journal of pharmaceutical sciences, 1981 , vol. 70, # 1 p. 87 - 89 Title/Abstract Full Text View citing articles Show Details
Spin-spin coupling constants
dimethylsulfoxide
1H-1H.
Trigo; Martinez; Galvez
Journal of pharmaceutical sciences, 1981 , vol. 70, #
Reference
1 p. 87 - 89 Title/Abstract Full Text View citing articles Show Details
Chemical Name: 2,2,4,4-tetradeuterio-tropan-3-one
4
Reaxys Registry Number: 145038
CAS Registry Number: 6204-39-3 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H9D4NO Molecular Weight: 143.166 InChI Key: QQXLDOJGLXJCSE-CQOLUAMGSA-N
2 prep out of 2 reactions.
Synthesize | Hide Details Find similar Chemical Names and Synonyms 2,2,4,4-tetradeuterio-tropan-3-one, 2,2,4,4-Tetradeuterio-tropan-3-on, 3-Oxo-(2,4-D4)tropan, 2,2,4,4-d4-Tropinon Identification Substance Label (1) Label
Reference
Ib
Blossey et al.
Tetrahedron, 1964 , vol. 20, p. 585,595 Full Text Show Details
Physical Data Melting Point (2) Melting Point
Solvent (Melting Point)
Reference
38 °C
Blossey et al.
Tetrahedron, 1964 , vol. 20, p. 585,595 Full Text Show Details
pentane
Closs
Journal of the American Chemical Society, 1959 , vol. 81, p. 5456,5459 Full Text View citing articles Show Details
Conformation (1) Object of Investigation
Reference
Conformation
Bishop et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 74 Full Text View citing articles Show Details
Spectra NMR Spectroscopy (1) Description (NMR Spectroscopy)
Reference
NMR
Fodor et al.
Tetrahedron, 1968 , vol. 24, p. 2357 Full Text View citing articles Show Details
Bishop et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 74 Full Text View citing articles Show Details
Mass Spectrometry (1)
Identification Physical Data (3) Spectra (2)
4
Reference Blossey et al.
Tetrahedron, 1964 , vol. 20, p. 585,595 Full Text Show Details
Chemical Name: tropinone picrate
5
no reactions.
Reaxys Registry Number: 3899668
CAS Registry Number: 1653-52-7 Type of Substance: heterocyclic Molecular Formula: C6H3N3O7*C8H13NO Linear Structure Formula: C8H13NO*C6H3N3O7
Molecular Weight: 368.303 InChI Key: FTXSRJKMBOSYQD-UHFFFAOYSA-N
Identification Physical Data (5) Spectra (1)
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropinone picrate, tropan-3-one; picrate, Tropan-3-on; Picrat Identification Substance Label (1) Label
Reference
22 - picrate
Leete, Edward
Phytochemistry (Elsevier), 1983 , vol. 22, # 3 p. 699 - 704 Title/Abstract Full Text View citing articles Show Details
Physical Data Melting Point (4) Melting Point
Solvent (Melting Point)
Comment (Melting Point)
Reference
218 - 219 °C
ethanol
Decomposition
Leete, Edward
Phytochemistry (Elsevier), 1983 , vol. 22, # 3 p. 699 - 704 Title/Abstract Full Text View citing articles Show Details
217 - 218 °C
H2O
Decomp.
Karrer; Alagil
Helvetica Chimica Acta, 1947 , vol. 30, p. 1777 Full Text View citing articles Show Details
210 - 250 °C
je nach der Art des Erhitzens.
Barrowcliff; Tutin
Journal of the Chemical Society, 1909 , vol. 95, p. 1966 Full Text View citing articles Show Details
220 °C
H2O
Decomp.
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 398 Full Text View citing articles Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
gelbe Nadeln
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 398 Full Text View citing articles Show Details
Spectra Mass Spectrometry (1) Description (Mass Spectrometry)
Reference
4
Leete, Edward
Phytochemistry (Elsevier), 1983 , vol. 22, # 3 p. 699 - 704 Title/Abstract Full Text View citing articles Show Details
spectrum
Chemical Name: Tropinone <N-14CH3> Reaxys Registry Number: 1526114
CAS Registry Number: 58139-15-4 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C7(14)CH13NO 6
1 prep out of 1 reactions.
Identification Physical Data (2)
3
0 prep out of 1 reactions.
Identification Physical Data (2) Bioactivity (1)
2
Molecular Weight: 141.186 InChI Key: QQXLDOJGLXJCSE-NJFSPNSNSA-N
Synthesize | Hide Details Find similar Chemical Names and Synonyms Tropinone <N-14CH3>, Tropinon-<N-14CH3>, N-Methyl-14C-tropanon Identification Derivative (1) Comment (Derivative)
Reference
Pikrat: F: 220grad
Basey; Woolley
Phytochemistry (Elsevier), 1975 , vol. 14, p. 2201,2203 Full Text Show Details
Purification (1) Reference Werner et al.
Justus Liebigs Annalen der Chemie, 1961 , vol. 644, p. 109,115 Full Text Show Details
Physical Data Melting Point (1) Melting Point
Reference
41 - 43 °C
Schmidt; Eling; McOwen
Journal of pharmaceutical sciences, 1968 , vol. 57, # 3 p. 443 - 446 Title/Abstract Full Text View citing articles Show Details
Crystal Property Description (1) Reference Basey; Woolley
Phytochemistry (Elsevier), 1975 , vol. 14, p. 2201,2203 Full Text Show Details
Chemical Name: tropinone
7
Reaxys Registry Number: 1524438
CAS Registry Number: 532-24-1 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H13NO Molecular Weight: 139.197 InChI Key: QQXLDOJGLXJCSE-RNFRBKRXSA-N
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropinone, Tropinon Identification Derivative (3) Comment (Derivative)
Reference
Picrat: F:216-217grad(Zers.)
Calvert; Hobson
Journal of the Chemical Society, 1965 , p. 2723,2726 Full Text Show Details
Hydrochlorid: F:206-208grad(Zers.)
Calvert; Hobson
Journal of the Chemical Society, 1965 , p. 2723,2726 Full Text Show Details
Hydrochlorid: F:206-208grad(Zers.)(siehe dagegen Willstaetter, Ber. 29 <1896> 393: F:188-189grad(Zers.))
Calvert; Hobson
Journal of the Chemical Society, 1965 , p. 2723,2726 Full Text Show Details
Physical Data Melting Point (1) Melting Point
Reference
41 °C
Calvert; Hobson
Journal of the Chemical Society, 1965 , p. 2723,2726 Full Text Show Details
Further Information (1) Description (Further Information)
Reference
Further information
Calvert; Hobson
Journal of the Chemical Society, 1965 , p. 2723,2726 Full Text Show Details
Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Fukuda, Yudai; Sone, Takeki; Sakuraba, Haruhiko; Araki, Tomohiro; Ohshima, Toshihisa; Shibata, Takeshi; Yoneda, Kazunari
FEBS Journal, 2015 , vol. 282, # 20 p. 3918 - 3928 Title/Abstract Full Text View citing articles Show Details
Chemical Name: tropan-3-one; tetrachloroaurate (III) Reaxys Registry Number: 3824313
no reactions.
Identification Physical Data (3)
2
Type of Substance: heterocyclic Molecular Formula: AuCl4*C8H13NO*H Linear Structure Formula: C8H13NO*AuCl4(1-)*H(1+)
8
Molecular Weight: 478.984 InChI Key: AWBQMFMICFYIGF-UHFFFAOYSA-K
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropan-3-one; tetrachloroaurate (III), Tropan-3-on; Tetrachloroaurat(III) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Au{X}4
X
4
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Au{X}4
X
4
Multi-Center Ligands (1)
Physical Data Melting Point (2) Melting Point
Solvent (Melting Point)
Comment (Melting Point)
Reference
163 °C
aq. HCl
Decomp.
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 398 Full Text View citing articles Show Details
163 °C
Decomp.
Ciamician; Silber
Chemische Berichte, 1896 , vol. 29, p. 490 Gazzetta Chimica Italiana, 1896 , vol. 26 II, p. 161 Full Text View citing articles Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
schwefelgelbe,mikroskopische Prismen
Willstaetter
Chemische Berichte, 1896 , vol. 29, p. 398 Full Text View citing articles Show Details
Chemical Name: tropan-3-one
9
Reaxys Registry Number: 4658547
CAS Registry Number: 532-24-1 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H13NO Molecular Weight: 139.197 InChI Key: QQXLDOJGLXJCSE-KNVOCYPGSA-N
0 prep out of 4 reactions.
Identification Spectra (2)
2
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropan-3-one, tropinone Identification Substance Label (2) Label
Reference
2
Casy; Dewar; Pascoe
Journal of Pharmacy and Pharmacology, 1992 , vol. 44, # 10 p. 787 - 790 Title/Abstract Full Text View citing articles Show Details
49
Mulekar, Satish V.; Berlin, Darrell K.
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4758 - 4767 Title/Abstract Full Text View citing articles Show Details
Spectra NMR Spectroscopy (2) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Temperature (NMR Spectroscopy)
Chemical shifts
17O
CD3CN acetonitrile
70 °C
Mulekar, Satish V.; Berlin, Darrell K.
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4758 - 4767 Title/Abstract Full Text View citing articles Show Details
Linewidth of NMR absorption
Mulekar, Satish V.; Berlin, Darrell K.
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4758 - 4767 Title/Abstract Full Text View citing articles Show Details
Chemical Name: Tropan-3-on
Reference
no reactions.
Reaxys Registry Number: 1099515
CAS Registry Number: 532-24-1 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H13NO Molecular Weight: 139.197 InChI Key: QQXLDOJGLXJCSE-BQBZGAKWSA-N
10
Synthesize | Hide Details Find similar Chemical Names and Synonyms Tropan-3-on Identification Substance Label (1) Label
Reference
3
Hanisch et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1977 , p. 1202,1203 Full Text Show Details
Identification Spectra (1)
1
Derivative (1) Comment (Derivative)
Reference
Hydrochlorid (3a): 13C-NMR (Tab. 1)
Hanisch et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1977 , p. 1202,1203 Full Text Show Details
Spectra NMR Spectroscopy (1) Description (NMR Spectroscopy)
Comment (NMR Spectroscopy)
NMR
13C (Tab. 1)
Reference Hanisch et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1977 , p. 1202,1203 Full Text Show Details
Chemical Name: Tropanon-3-14C Reaxys Registry Number: 1449591
Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C7(14)CH13NO
1 prep out of 1 reactions.
Identification
1
1 prep out of 1 reactions.
Identification Physical Data (1)
1
Molecular Weight: 141.186 InChI Key: QQXLDOJGLXJCSE-PPJXEINESA-N
11
Synthesize | Hide Details Find similar Chemical Names and Synonyms Tropanon-3-14C Identification Substance Label (1) Label
Reference
Tab.II
Eling et al.
Journal of Pharmaceutical Sciences, 1968 , vol. 57, p. 1357,1359 Full Text Show Details
Chemical Name: 6,7-d2-Tropinon Reaxys Registry Number: 1450261
CAS Registry Number: 92475-39-3 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H11D2NO Molecular Weight: 141.181 InChI Key: QQXLDOJGLXJCSE-PBNXXWCMSA-N
12
Synthesize | Hide Details Find similar Chemical Names and Synonyms 6,7-d2-Tropinon
Identification Substance Label (1) Label
Reference
Ic
Blossey et al.
Tetrahedron, 1964 , vol. 20, p. 585,595 Full Text Show Details
Physical Data Melting Point (1) Melting Point
Reference
42 °C
Blossey et al.
Tetrahedron, 1964 , vol. 20, p. 585,595 Full Text Show Details
Chemical Name: Tropinon-6,7-T
no reactions.
Physical Data (1)
1
Physical Data (1)
1
Reaxys Registry Number: 1450270
Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H11T2NO Molecular Weight: 143.181 InChI Key: QQXLDOJGLXJCSE-IPKYPDTESA-N
13
Synthesize | Hide Details Find similar Chemical Names and Synonyms Tropinon-6,7-T Physical Data Further Information (1) Description (Further Information)
Reference
Further information
Hespe et al.
Recueil des Travaux Chimiques des Pays-Bas, 1965 , vol. 84, p. 476 Full Text Show Details
Chemical Name: tropan-3-one; perchlorate Reaxys Registry Number: 3752253
CAS Registry Number: 114983-56-1 Type of Substance: heterocyclic Molecular Formula: C8H13NO*ClHO4
Linear Structure Formula: C8H13NO*ClHO4
Molecular Weight: 239.656 InChI Key: OCHHQTXMVRKMPD-UHFFFAOYSA-N
14
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropan-3-one; perchlorate, Tropan-3-on; Perchlorat
no reactions.
Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Comment (Melting Point)
Reference
221.5 - 222 °C
ethanol
Decomp.
Leonard; Morrow
Journal of the American Chemical Society, 1958 , vol. 80, p. 371,373 Full Text View citing articles Show Details
Chemical Name: <N-methyl-14C>tropinone Reaxys Registry Number: 4308232
CAS Registry Number: 58139-15-4 Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C7(14)CH13NO
0 prep out of 2 reactions.
1
no reactions.
Identification
1
1
Molecular Weight: 141.186 InChI Key: QQXLDOJGLXJCSE-BPNHSZGLSA-N
15
Synthesize | Hide Details Find similar Chemical Names and Synonyms <N-methyl-14C>tropinone, (N-methyl-14C)tropinone Chemical Name: 2,2,4,4-tetradeuterio-tropan-3-one; deuterio chloride Reaxys Registry Number: 4924634
CAS Registry Number: 118019-99-1 Type of Substance: heterocyclic Molecular Formula: C8H13NO*ClH Linear Structure Formula: C8H9(2)H4NO*Cl(2)H
Molecular Weight: 180.619 InChI Key: HUGYQXFQBHWMQD-LSXHDFSKSA-N
16
Synthesize | Hide Details Find similar Chemical Names and Synonyms 2,2,4,4-tetradeuterio-tropan-3-one; deuterio chloride, 2,2,4,4-Tetradeuterio-tropan-3-on; Deuteriochlorid Identification Related Structure (1) Related Structure
Reference
Gleichgewicht der Konformeren.
Closs
Journal of the American Chemical Society, 1959 , vol. 81, p. 5456,5459 Full Text View citing articles Show Details
Chemical Name: tropan-3-one; toluene-4-sulfonate Reaxys Registry Number: 5399086
Type of Substance: heterocyclic Molecular Formula: C7H8O3S*C8H13NO Linear Structure Formula: C8H13NO*C7H8O3S Molecular Weight: 311.402
0 prep out of 1 reactions.
InChI Key: HQFDXBLYKQJFME-UHFFFAOYSA-N
17
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropan-3-one; toluene-4-sulfonate Chemical Name: (exo)-2-deutero-8-methyl-8-azabicyclo<3.2.1>octan-3-one Reaxys Registry Number: 5862224
Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H12DNO Molecular Weight: 140.189 InChI Key: QQXLDOJGLXJCSE-LCZBAXFZSA-N
18
1 prep out of 2 reactions.
Identification Physical Data (1) Spectra (6)
1
Synthesize | Hide Details Find similar Chemical Names and Synonyms (exo)-2-deutero-8-methyl-8-azabicyclo<3.2.1>octan-3-one, (exo)-2-deutero-8-methyl-8-azabicyclo[3.2.1]octan-3-one Identification Substance Label (1) Label
Reference
8e
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
40.5 - 42 °C
pentane
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Spectra NMR Spectroscopy (4) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Comment (NMR Spectroscopy)
Chemical shifts
1H
CDCl3
Reference Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626
Title/Abstract Full Text Show Details
Chemical shifts
13C
CDCl3
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Spin-spin coupling constants
CDCl3
1H-1H
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Spin-spin coupling constants
CDCl3
1H-13C.
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Description (IR Spectroscopy)
Solvent (IR Spectroscopy)
Comment (IR Spectroscopy)
Reference
Bands
KBr
3387 - 1348 cm**(-1)
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
IR Spectroscopy (1)
Mass Spectrometry (1) Description (Mass Spectrometry)
Reference
chemical ionization (CI) spectrum
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Chemical Name: (exo, exo)-2,4-dideutero-8-methyl-8-azabicyclo<3.2.1>octan-3-one Reaxys Registry Number: 5862910
Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H11D2NO Molecular Weight: 141.181 InChI Key: QQXLDOJGLXJCSE-ZPJNDBNZSA-N
19
2 prep out of 2 reactions.
Synthesize | Hide Details Find similar Chemical Names and Synonyms (exo, exo)-2,4-dideutero-8-methyl-8-azabicyclo<3.2.1>octan-3-one, (exo, exo)-2,4-dideutero-8-methyl-8-azabicyclo[3.2.1]octan-3-one Identification Substance Label (1) Label
Reference
17
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
42 - 43 °C
pentane
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626
Identification Physical Data (1) Spectra (6)
1
Title/Abstract Full Text Show Details
Spectra NMR Spectroscopy (4) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Comment (NMR Spectroscopy)
Chemical shifts
1H
CDCl3
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Chemical shifts
13C
CDCl3
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Spin-spin coupling constants
CDCl3
1H-1H
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Spin-spin coupling constants
CDCl3
1H-13C.
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Description (IR Spectroscopy)
Solvent (IR Spectroscopy)
Comment (IR Spectroscopy)
Reference
Bands
KBr
2932 - 453 cm**(-1)
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Reference
IR Spectroscopy (1)
Mass Spectrometry (1) Description (Mass Spectrometry)
Reference
chemical ionization (CI) spectrum
Majewski, Marek; Zheng, Guo-Zhu
Canadian Journal of Chemistry, 1992 , vol. 70, # 10 p. 2618 - 2626 Title/Abstract Full Text Show Details
Chemical Name: <methyl-C2H3>-tropinone Reaxys Registry Number: 6645322
Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H10D3NO Molecular Weight: 142.173 InChI Key: QQXLDOJGLXJCSE-KYWJIGBISA-N
20
Synthesize | Hide Details Find similar Chemical Names and Synonyms <methyl-C2H3>-tropinone, (methyl-C2H3)-tropinone Identification Substance Label (1) Label
Reference
1 prep out of 2 reactions.
Identification Physical Data (1) Spectra (1)
1
Robins, Richard J.; Bachmann, Peter; Woolley, Jack G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 6 p. 615 - 620 Title/Abstract Full Text View citing articles Show Details
<methyl-C2H3>-5
Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
217 °C
acetone H2O
Robins, Richard J.; Bachmann, Peter; Woolley, Jack G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 6 p. 615 - 620 Title/Abstract Full Text View citing articles Show Details
Spectra Mass Spectrometry (1) Description (Mass Spectrometry)
Reference
spectrum
Robins, Richard J.; Bachmann, Peter; Woolley, Jack G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 6 p. 615 - 620 Title/Abstract Full Text View citing articles Show Details
Chemical Name: [15N]-tropinone
no reactions.
Bioactivity (2)
Reaxys Registry Number: 9122540
Type of Substance: heterocyclic Molecular Formula: C8H13NO Linear Structure Formula: C8H13(15)NO
Molecular Weight: 140.191 InChI Key: QQXLDOJGLXJCSE-MSUMSSKXSA-N
21
Synthesize | Hide Details Find similar Chemical Names and Synonyms [15N]-tropinone Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
Bioactivities present
Reference
Scholl, Yvonne; Hoeke, Dirk; Draeger, Birgit
Phytochemistry, 2001 , vol. 58, # 6 p. 883 - 889 Title/Abstract Full Text View citing articles Show Details
Ecotoxicology (1) 1 of 1
Effect (Ecotoxicology)
biotransformation
Species or TestSystem (Ecotoxicology)
Calystegia sepium
Metabolite (Ecotoxicology)
C7H13(15)NO3 [Reaxys RN: 9127670] ; C7H13(15)NO4 [Reaxys RN: 9132035] ; C7H13(15)NO4 [Reaxys RN: 9132029]
Comment (Ecotoxicology)
Further metabolite(s)
Reference
Scholl, Yvonne; Hoeke, Dirk; Draeger, Birgit
Phytochemistry, 2001 , vol. 58, # 6 p. 883 - 889 Title/Abstract Full Text View citing articles Show Details
1
Chemical Name: [2-(2)H]tropinone
1 prep out of 1 reactions.
Reaxys Registry Number: 19982561
CAS Registry Number: 1210930-23-6 Molecular Formula: C8H13NO Linear Structure Formula: C8H12(2)HNO
Spectra (4)
1
Molecular Weight: 140.189 InChI Key: QQXLDOJGLXJCSE-RAMDWTOOSA-N
22
Synthesize | Hide Details Find similar Chemical Names and Synonyms [2-(2)H]tropinone Spectra NMR Spectroscopy (2) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Frequency (NMR Spectroscopy)
Chemical shifts Spectrum
1H
chloroform-d1
Chemical shifts Spectrum
13C
chloroform-d1
Location
Reference
400 MHz
supporting information
Fournial, Anais; Ranaivondrambola, Tsiresy; Mathe-Allainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 - 156 Title/Abstract Full Text View citing articles Show Details
100 MHz
supporting information
Fournial, Anais; Ranaivondrambola, Tsiresy; Mathe-Allainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 - 156 Title/Abstract Full Text View citing articles Show Details
Mass Spectrometry (2) Description (Mass Spectrometry)
Reference
ESI (Electrospray ionisation) Spectrum
Fournial, Anais; Ranaivondrambola, Tsiresy; Mathe-Allainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 - 156 Title/Abstract Full Text View citing articles Show Details
HRMS (High resolution mass spectrometry) ESI (Electrospray ionisation) Spectrum
Fournial, Anais; Ranaivondrambola, Tsiresy; Mathe-Allainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 - 156 Title/Abstract Full Text View citing articles Show Details
Chemical Name: [2,5-(2)H2]tropinone Reaxys Registry Number: 19982563
CAS Registry Number: 1210930-20-3 Molecular Formula: C8H13NO Linear Structure Formula: C8H11(2)H2NO
Molecular Weight: 141.181 InChI Key: QQXLDOJGLXJCSE-QFIQSOQBSA-N
23
Synthesize | Hide Details Find similar Chemical Names and Synonyms [2,5-(2)H2]tropinone
1 prep out of 1 reactions.
Spectra (3)
1
Spectra NMR Spectroscopy (2) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Frequency (NMR Spectroscopy)
Chemical shifts Spectrum
1H
chloroform-d1
Chemical shifts Spectrum
13C
chloroform-d1
Location
Reference
400 MHz
supporting information
Fournial, Anais; Ranaivondrambola, Tsiresy; Mathe-Allainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 - 156 Title/Abstract Full Text View citing articles Show Details
100 MHz
supporting information
Fournial, Anais; Ranaivondrambola, Tsiresy; Mathe-Allainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 - 156 Title/Abstract Full Text View citing articles Show Details
Mass Spectrometry (1) Description (Mass Spectrometry)
Reference
ESI (Electrospray ionisation) Spectrum
Fournial, Anais; Ranaivondrambola, Tsiresy; Mathe-Allainmat, Monique; Robins, Richard J.; Lebreton, Jacques
European Journal of Organic Chemistry, 2010 , # 1 p. 152 - 156 Title/Abstract Full Text View citing articles Show Details
Chemical Name: tropinone hydrochloride
no reactions.
Reaxys Registry Number: 22750284
Molecular Formula: C8H13NO*ClH Linear Structure Formula: C8H13NO*ClH Molecular Weight: 175.658 InChI Key: HUGYQXFQBHWMQD-UKMDXRBESA-N
24
Physical Data (1) Spectra (1)
1
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropinone hydrochloride Physical Data Conformation (1) Object of Investigation
Reference
Conformation
Lazny, Ryszard; Ratkiewicz, Artur; Nodzewska, Aneta; Wynimko, Anna; Siergiejczyk, Leszek
Tetrahedron, 2012 , vol. 68, # 31 p. 6158 - 6163 Title/Abstract Full Text View citing articles Show Details
Spectra NMR Spectroscopy (1) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Temperature (NMR Spectroscopy)
Frequency (NMR Spectroscopy)
Chemical shifts
13C
water
25 °C
100 MHz
Chemical Name: tropinone di(4-nitrobenzoate) Reaxys Registry Number: 28330751
Reference Lazny, Ryszard; Ratkiewicz, Artur; Nodzewska, Aneta; Wynimko, Anna; Siergiejczyk, Leszek
Tetrahedron, 2012 , vol. 68, # 31 p. 6158 - 6163 Title/Abstract Full Text View citing articles Show Details
1 prep out of 1 reactions.
Physical Data (6)
1
Molecular Formula: 2C7H5NO4*C8H13NO Linear Structure Formula: 2C7H5NO4*C8H13NO Molecular Weight: 473.439 InChI Key: GEDZLVFZEDXUAT-UHFFFAOYSA-N
25
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropinone di(4-nitrobenzoate) Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
132 133 °C
toluene
Reference Sidorowicz, Katarzyna; Lazny, Ryszard; Nodzewska, Aneta; Wolosewicz, Karol; Ratkiewicz, Artur; Urbanczyk-Lipkowska, Zofia; Kalicki, Przemyslaw
Tetrahedron, 2015 , vol. 71, # 32 art. no. 26735, p. 5148 - 5158 Title/Abstract Full Text View citing articles Show Details
Density (1) Density 1.427 g·cm-3
Type (Density)
Reference
crystallographic
Sidorowicz, Katarzyna; Lazny, Ryszard; Nodzewska, Aneta; Wolosewicz, Karol; Ratkiewicz, Artur; Urbanczyk-Lipkowska, Zofia; Kalicki, Przemyslaw
Tetrahedron, 2015 , vol. 71, # 32 art. no. 26735, p. 5148 - 5158 Title/Abstract Full Text View citing articles Show Details
Crystal Phase (1) Description (Crystal Phase)
Reference Sidorowicz, Katarzyna; Lazny, Ryszard; Nodzewska, Aneta; Wolosewicz, Karol; Ratkiewicz, Artur; Urbanczyk-Lipkowska, Zofia; Kalicki, Przemyslaw
Tetrahedron, 2015 , vol. 71, # 32 art. no. 26735, p. 5148 - 5158 Title/Abstract Full Text View citing articles Show Details
Crystal growth
Crystal Property Description (1) Colour & Other Properties
Reference Sidorowicz, Katarzyna; Lazny, Ryszard; Nodzewska, Aneta; Wolosewicz, Karol; Ratkiewicz, Artur; Urbanczyk-Lipkowska, Zofia; Kalicki, Przemyslaw
Tetrahedron, 2015 , vol. 71, # 32 art. no. 26735, p. 5148 - 5158 Title/Abstract Full Text View citing articles Show Details
yellow
Crystal System (1) Crystal System Monoclinic
Reference Sidorowicz, Katarzyna; Lazny, Ryszard; Nodzewska, Aneta; Wolosewicz, Karol; Ratkiewicz, Artur; Urbanczyk-Lipkowska, Zofia; Kalicki, Przemyslaw
Tetrahedron, 2015 , vol. 71, # 32 art. no. 26735, p. 5148 - 5158 Title/Abstract Full Text View citing articles Show Details
Space Group (1) Space Group 14
Comment (Space Group)
Reference
a = 14.899 Å; b = 7.44 Å; c = 20.4172 Å; β = 103.245 °; Z = 4; Method = Single crystal X-ray diffraction
Sidorowicz, Katarzyna; Lazny, Ryszard; Nodzewska, Aneta; Wolosewicz, Karol; Ratkiewicz, Artur; Urbanczyk-Lipkowska, Zofia; Kalicki, Przemyslaw
Tetrahedron, 2015 , vol. 71, # 32 art. no. 26735, p. 5148 - 5158 Title/Abstract Full Text View citing articles Show Details
Chemical Name: tropinone aldol Reaxys Registry Number: 30601753
Molecular Formula: C4H8O2*C8H13NO Linear Structure Formula: C4H8O2*C8H13NO Molecular Weight: 227.304 InChI Key: LEWASUGYQFQWPT-UKMDXRBESA-N 26
Synthesize | Hide Details Find similar Chemical Names and Synonyms tropinone aldol
no reactions.
1