Reaxys
PubChem
eMolecules
Bioactivities (72)
LabNetwork
SigmaAldrich
Reactions (6)
Substances (6)
Structure
Targets (6)
Citations (124)
Structure/Compound Data Chemical Name: Tiletamine Reaxys Registry Number: 8411503
Type of Substance: heterocyclic Molecular Formula: C12H17NOS Linear Structure Formula: C12H17NOS Molecular Weight: 223.339 InChI Key: QAXBVGVYDCAVLV-UHFFFAOYSA-N
N° of preparations All Preps | All Reactions
Available Data
2 prep out of 3 reactions.
4 prep out of 4 reactions.
Target
N° of ref.
Druglikeness
Bioactivity
Identification Physical Data (1) Spectra (5) Other Data (10)
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102
Druglikeness
Bioactivity
Identification Physical Data (2) Spectra (4)
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24
1
Synthesize | Show Details Find similar Chemical Name: CI-634 Reaxys Registry Number: 8869472
Type of Substance: heterocyclic Molecular Formula: C12H17NOS*ClH Linear Structure Formula: C12H17NOS*ClH Molecular Weight: 259.8 InChI Key: ZUYKJZQOPXDNOK-UHFFFAOYSA-N 2
Highest Clinical Phase: Marketed
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3
mixture (composition completely given) :
4-(o-fluorophenyl)-6,8-dihydro-1,3,8-trimethylpyrazolo(3,4-e(1,4)diazepin-7(1H)one hydrochloride CI-634 Hide Details
Chemical Name: tiletamine hydrochloride; zolazepam hydrochloride; mixture of
no reactions.
Bioactivity
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2
Reaxys Registry Number: 8896825 Type of Substance: mixture (composition completely given)
Chemical Names and Synonyms tiletamine hydrochloride; zolazepam hydrochloride; mixture of, Telazol Composition CI-634 (50 weight percent)
4-(o-fluorophenyl)-6,8-dihydro-1,3,8-trimethylpyrazolo(3,4e(1,4)diazepin-7(1H)-one hydrochloride (50 weight percent)
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Bioactivity In vitro: Efficacy (1) Quantitative Results pX
Parameter
Value (qual)
Activity
ND
Value (quant)
Unit
Action on Target
Target
Tissue/Organ
Cell
Bioassay
Dose
Effect
120 mg/kg
Reference (expand all/collapse all) Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Wong, Anne; Bandiera, Stelvio M.
Biochemical Pharmacology, 1998 , vol. 55, # 2 p. 201 - 207 Title/Abstract Full Text View citing articles Show Details
In vivo: Animal Model (5) Quantitative Results pX
Parameter
Value (qual)
Activity
ND
Value (quant)
Unit
Action on Target
Animal Model
Biological Species
Route of administration
Dose
intraperitoneal administration
120 mg/kg
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
intraperitoneal administration
20 120 mg/kg
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Dosing regimen
Effect
Reference (expand all/collapse all)
Wong, Anne; Bandiera, Stelvio M.
Biochemical Pharmacology, 1998 , vol. 55, # 2 p. 201 - 207 Title/Abstract Full Text View citing articles Show Details
Activity
ND
Wong, Anne; Bandiera, Stelvio M.
Biochemical Pharmacology, 1996 , vol. 52, # 5 p. 735 - 742 Title/Abstract Full Text View citing articles Show Details
Activity
ND
intraperitoneal administration
120 mg/kg
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
intraperitoneal administration
20 120 mg/kg
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
intraperitoneal administration
20 120 mg/kg
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Wong, Anne; Bandiera, Stelvio M.
Biochemical Pharmacology, 1996 , vol. 52, # 5 p. 735 - 742 Title/Abstract Full Text View citing articles Show Details
Activity
ND
Wong, Anne; Bandiera, Stelvio M.
Biochemical Pharmacology, 1996 , vol. 52, # 5 p. 735 - 742 Title/Abstract Full Text View citing articles Show Details
Activity
ND
Wong, Anne; Bandiera, Stelvio M.
Biochemical Pharmacology, 1996 , vol. 52, # 5 p. 735 - 742 Title/Abstract Full Text View citing articles Show Details
Chemical Name: tiletamine hydrochloride
no reactions.
Druglikeness
Identification
Show Targets
2
no reactions.
Identification Other Data (1)
Show Targets
1
Reaxys Registry Number: 28570198
Molecular Formula: C12H17NOS*(x)ClH Linear Structure Formula: C12H17NOS*xClH InChI Key: ZUYKJZQOPXDNOK-UHFFFAOYSA-N 4
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5
mixture (composition partially given) :
phenylmethanethiol hexadecanoic acid 4-methyl-4-hydroxypentan-2-one 1 (1,1 dimethylethyl) 2 methoxy 4 methyl 3,5 dinitrobenzene Tiletamine Alpine marmot temporal gland secretion, ethanol extract
Chemical Name: Alpine marmot temporal gland secretion, ethanol extrct Reaxys Registry Number: 8477672 Type of Substance: mixture (composition partially given)
Hide Details Chemical Names and Synonyms Alpine marmot temporal gland secretion, ethanol extrct Composition phenylmethanethiol
hexadecanoic acid
4-methyl-4-hydroxypentan-2-one
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1 (1,1 dimethylethyl) 2 methoxy 4 methyl 3,5 dinitrobenzene
Tiletamine
Alpine marmot temporal gland secretion, ethanol extract
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Identification Substance Label (1) Label
Reference
EE
Bel; Coulon; Sreng; Allaine; Bagneres; Clement
Journal of Chemical Ecology, 1999 , vol. 25, # 10 p. 2267 - 2283 Title/Abstract Full Text View citing articles Show Details
Other Data Isolation from Natural Product (1) Isolation from Natural Product
Reference
secretion exudate of the temporal gland of Alpine marmots, Marmota marmota
Bel; Coulon; Sreng; Allaine; Bagneres; Clement
Journal of Chemical Ecology, 1999 , vol. 25, # 10 p. 2267 - 2283 Title/Abstract Full Text View citing articles Show Details
Chemical Name: Tiletamine Urethane
6
Reaxys Registry Number: 30127777
Molecular Formula: C3H7NO2*C12H17NOS Linear Structure Formula: C3H7NO2*C12H17NOS Molecular Weight: 312.433 InChI Key: ZEOXVZIDUMTLQX-UHFFFAOYSA-N
no reactions.
Druglikeness
Identification
Show Targets
1
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