2-Methyl-2-propylpropane-1,3-diyl dicarbamate [Meprobamate]

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1. Query

O

O

NH 2

O

O

Results

Date

8 reactions in Reaxys

2016-09-03 02h:48m:01s (EST)

H 2N

Search as: As drawn, No mixtures, No charges, No radicals

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Cl

Cl

OH OH

O

O

O

O

O NH 2

H 2N

Rx-ID: 62135 View in Reaxys 1/8 Yield

Conditions & References With [14C]-Antipyrine, chloroform, toluene, und Behandeln der Reaktionsloesung mit Ammoniak Ludwig; Piech; Journal of the American Chemical Society; vol. 73; (1951); p. 5779 View in Reaxys Patent; Carter Prod.Inc.; US2724720; (1953) View in Reaxys Patent; Abbott Labor; US2806053; (1956) View in Reaxys (i), (ii) aq. NH3, Multistep reaction Schneider,G. et al.; Monatshefte fuer Chemie; vol. 94; (1963); p. 426 - 433 View in Reaxys

OH OH

N

Na

O

O

O

NH 2

O

H 2N

Rx-ID: 1008981 View in Reaxys 2/8 Yield

Conditions & References With trifluoroacetic acid in tetrahydrofuran Loev,B.; Kormendy,M.F.; Journal of Organic Chemistry; vol. 28; (1963); p. 3421 - 3426 View in Reaxys

OH OH

H 2N

O

O

O

O

O

NH 2

NH 2

H 2N

Rx-ID: 747540 View in Reaxys 3/8 Yield

Conditions & References With propan-1-ol, aluminum isopropoxide Patent; Berkeley Chem.Corp.; US2837560; (1956) View in Reaxys With aluminum tri-n-butoxide, butan-1-ol Patent; Berkeley Chem.Corp.; US2837560; (1956) View in Reaxys With Neutral lead acetate, T= 160 °C Ferrari; Chimica e l'Industria (Milan, Italy); vol. 40; (1958); p. 13 View in Reaxys

OH OH

O

O

O

O

O

O

NH 2

NH 2

H 2N

Rx-ID: 751490 View in Reaxys 4/8 Yield

Conditions & References With aluminum isopropoxide, T= 175 °C Ghielmetti; Farmaco, Edizione Scientifica; vol. 11; (1956); p. 1014,1016 View in Reaxys

Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.

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2016-09-03 03:01:15


With molybdenum(VI) oxide Mastagli,P.; Francois,G.; Bulletin de la Societe Chimique de France; (1960); p. 808 - 810 View in Reaxys

O

S

O

NH 2

S

O

H 2N

O

O

NH 2

O

H 2N

Rx-ID: 1054122 View in Reaxys 5/8 Yield

Conditions & References With sodium hydroxide, dihydrogen peroxide Ludwig,B.J. et al.; Journal of Medicinal Chemistry; vol. 7; (1964); p. 174 - 177 View in Reaxys

OH OH

O

O

NH 2

O

O

H 2N

Rx-ID: 22642559 View in Reaxys 6/8 Yield

Conditions & References Reaction Steps: 2 2: aq. H2O2, aq. NaOH With sodium hydroxide, dihydrogen peroxide Ludwig,B.J. et al.; Journal of Medicinal Chemistry; vol. 7; (1964); p. 174 - 177 View in Reaxys

Cl

OH OH

O O

O

O

NH 2

O

O

H 2N

Rx-ID: 1322588 View in Reaxys 7/8 Yield

Conditions & References (i) Py, (ii) liq. NH3, Multistep reaction Fessenden; Coon; Journal of medicinal chemistry; vol. 8; nb. 5; (1965); p. 604 - 608 View in Reaxys

O

O NH 2

O

O

H 2N

Rx-ID: 6984850 View in Reaxys 8/8 Yield

Conditions & References Patent; Kejha; Hebky; CS97217; ; vol. 56; nb. 3355; (1962) View in Reaxys Patent; Berkeley Chem. Corp.; US2934559; (1956); ; nb. 19497; (1960) View in Reaxys Patent; Millmaster Onyx Corp.; US3219686; (1961); ; vol. 64; nb. 6507; (1966) View in Reaxys Patent; D'Amato; Teotino; FI31146; (1961); ; vol. 58; nb. 6702e; (1963) View in Reaxys Patent; Romania, Ministr. Petr. Chem. Ind.; FR1443093; (1966); ; vol. 66; nb. 28410v View in Reaxys Patent; Egyesult Gyogyszer es Tapszergyar; HU150469; (1962); ; vol. 60; nb. 2790e; (1964) View in Reaxys Patent; Univ.Oil Prod.; US3173941; (1965); ; vol. 62; nb. 16070b; (1965) View in Reaxys

Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.

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Patent; Egyesult Gyogyszer es Tapszergyar; AT239252; (1965); ; vol. 62; nb. 16070d; (1965) View in Reaxys The chemical names of the reference compounds are as follows: Meprobamate: 2-methyl-2-propyl-1,3-propanediol dicarbamate; Paracetamol: N-(hydroxyphenyl)acetamide; Phenylbutazone: 4-butyl-1,2-diphenyl-3,5-pyrazolidinedione. Patent; EGYT Gyogyszervegyeszeti Gyar; US4316022; (1982); (A1) English View in Reaxys 14. and at least one number selected from the group consisting of Pentylenetetrazole Methylphenidate Bunamidine Pyrvinium pamoate Meprobamate Phenacemide Dipyridamol Indomethacin Nicotinamide ... Patent; The Regents of the University of Michigan; US4034087; (1977); (A1) English View in Reaxys

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