4-Hydroxy-3,5-dimethoxybenzaldehyde (Syringaldehyde) by Asch

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8 substances in Reaxys

2017-10-08 12h:27m:28s (EST)

7 substances in Reaxys

2017-10-08 12h:28m:45s (EST)

1. Query

Search as: As drawn, No salts, No mixtures, No charges, No radicals 2. Query

(1. Query) AND NOT itemno in (8)

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Reaxys ID 784514 View in Reaxys

1/7 CAS Registry Number: 134-96-3 Chemical Name: syringic aldehyde; Syringaldehyde Linear Structure Formula: C6H2CHO(OH)(OCH3)2 Molecular Formula: C9H10O4 Molecular Weight: 182.176 Type of Substance: isocyclic InChI Key: KCDXJAYRVLXPFO-UHFFFAOYSA-N Note:

O O HO

Substance Label (116) Label References SYA

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14w

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12a

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4{9}

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3{5}

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Horta, Lívia P.; Mota, Yane C.C.; Barbosa, Gisele Maria; Braga, Taniris C.; Marriel, Ivanildo E.; De Fátima, Ângelo; Modolo, Luzia V.; Journal of the Brazilian Chemical Society; vol. 27; nb. 8; (2016); p. 1512 1519, View in Reaxys

Jao, Chen-Wei; Hung, Tzu-Heng; Chang, Chi-Fen; Chuang, Ta-Hsien; Molecules; vol. 21; nb. 11; (2016); Art.No: 1605, View in Reaxys

Kärkäs, Markus D.; Bosque, Irene; Matsuura, Bryan S.; Stephenson, Corey R. J.; Organic Letters; vol. 18; nb. 19; (2016); p. 5166 - 5169, View in Reaxys

Fuganti, Claudio; Serra, Stefano; Journal of Chemical Research, Miniprint; nb. 10; (1998); p. 2769 - 2782, View in Reaxys; Wang, Ying; Yang, Min; Yuan, Cheng-Shan; Han, Yi-Feng; Jia, Zhong-Jian; Pharmazie; vol. 58; nb. 8; (2003); p. 596 - 598, View in Reaxys; Wittayalai, Sawangjitt; Mahidol, Chulabhorn; Prachyawarakorn, Vilailak; Prawat, Hunsa; Ruchirawat, Somsak; Phytochemistry; vol. 99; (2014); p. 121 126, View in Reaxys; Chen, Xiu-Juan; Mei, Wen-Li; Cai, Cai-Hong; Guo, Zhi-Kai; Song, Xi-Qiang; Dai, Hao-Fu; Phytochemistry Letters; vol. 9; nb. 1; (2014); p. 107 - 112, View in Reaxys; Lavaud, Alexis; Richomme, Pascal; Gatto, Julia; Aumond, Marie-Christine; Poullain, Cyril; Litaudon, Marc; Andriantsitohaina, Ramaroson; Guilet, David; Phytochemistry; vol. 109; (2015); p. 103 - 110, View in Reaxys

Lobbes; Fitznar; Kattner; Analytical Chemistry; vol. 71; nb. 15; (1999); p. 3008 - 3012, View in Reaxys; Lin, Wei-Yu; Teng, Che-Ming; Tsai, Ian-Lih; Chen, Ih-Sheng; Phytochemistry; vol. 53; nb. 8; (2000); p. 833 836, View in Reaxys; Kim, Ki Hyun; Moon, Eunjung; Lee, Seoung Rak; Park, Kyoung Jin; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro; Journal of the Brazilian Chemical Society; vol. 26; nb. 11; (2015); p. 2307 - 2312, View in Reaxys

Loeber, Stefan; Rodriguez-Loaiza, Pilar; Gmeiner, Peter; Organic Letters; vol. 5; nb. 10; (2003); p. 1753 1755, View in Reaxys; Mahajan, Rajesh P.; Patil, Shamkant L.; Mali, Raghao S.; Organic Preparations and Procedures International; vol. 37; nb. 3; (2005); p. 286 - 290, View in Reaxys; Hossain, Sk. Ugir; Bhattacharya, Sudin; Bioorganic and Medicinal Chemistry Letters; vol. 17; nb. 5; (2007); p. 1149 - 1154, View in Reaxys; Nazreen, Syed; Alam, Mohammad Sarwar; Hamid, Hinna; Yar, Mohammad Shahar; Dhulap, Abhijeet; Alam, Perwez; Pasha, Mohammad Abdul Qadar; Bano, Sameena; Alam, Mohammad Mahboob; Haider, Saqlain; Kharbanda, Chetna; Ali, Yakub; Pillai, Kolakappi; Archiv der Pharmazie; vol. 348; nb. 6; (2015); p. 421 - 432, View in Reaxys

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Bem, Marioara; Culita, Daniela C.; Caproiu, Miron T.; Constantinescu, Titus; Banciu, Mircea D.; Revue Roumaine de Chimie; vol. 48; nb. 5; (2003); p. 387 - 392, View in Reaxys; Iniyavan; Sarveswari; Vijayakumar; Research on Chemical Intermediates; vol. 41; nb. 10; (2015); p. 7413 - 7426, View in Reaxys; Jiang, Jian-An; Du, Jia-Lei; Zhang, Zhong-Nan; Zhai, Jiao-Jiao; Ji, Ya-Fei; Synthetic Communications; vol. 44; nb. 10; (2014); p. 1430 - 1440, View in Reaxys

Sinha, Arun K.; Sharma, Anuj; Joshi, Bhupendra P.; Tetrahedron; vol. 63; nb. 4; (2007); p. 960 - 965, View in Reaxys; Gu, Ya-Kun; Han, Ying; Chen, Chuan-Feng; Supramolecular Chemistry; vol. 27; nb. 5-6; (2015); p. 357 - 363, View in Reaxys

Beejmohun, Vickram; Grand, Eric; Mesnard, Francois; Fliniaux, Marc-Andre; Kovensky, Jose; Tetrahedron Letters; vol. 45; nb. 47; (2004); p. 8745 - 8747, View in Reaxys; Zabinski, Jerzy; Wolska, Irena; Maciejewska, Dorota; Journal of Molecular Structure; vol. 833; nb. 1-3; (2007); p. 74 - 81, View in Reaxys; Njiojob, Costyl N.; Rhinehart, Jennifer L.; Bozell, Joseph J.; Long, Brian K.; Journal of Organic Chemistry; vol. 80; nb. 3; (2015); p. 1771 - 1780, View in Reaxys

Lee, Eun Ju; Kim, So Ra; Kim, Jinwoong; Kim, Young Choong; Planta Medica; vol. 68; nb. 5; (2002); p. 407 - 411, View in Reaxys; Chen, Jih-Jung; Chen, Po-Hou; Liao, Chang-Hui; Huang, Shi-Yu; Chen, IhSheng; Journal of Natural Products; vol. 70; nb. 9; (2007); p. 1444 - 1448, View in Reaxys; Li, Su-Mei; Yang, Xian-Wen; Shen, Yun-Heng; Feng, Lin; Wang, Yue-Hu; Zeng, Hua-Wu; Liu, Xiao-Hua; Tian, JunMian; Shi, Ya-Na; Long, Chun-Lin; Zhang, Wei-Dong; Phytochemistry; vol. 69; nb. 11; (2008); p. 2200 2204, View in Reaxys; Sribuhom, Thurdpong; Sriphana, Uraiwan; Thongsri, Yordhathai; Yenjai, Chavi; Phytochemistry Letters; vol. 11; (2015); p. 80 - 84, View in Reaxys

Rajput, Jaspreet Kaur; Kaur, Gagandeep; Chinese Journal of Catalysis; vol. 34; nb. 9; (2013); p. 1697 1704, View in Reaxys; Kim, Jong H.; Chan, Kathleen L.; Mahoney, Noreen; International Journal of Molecular Sciences; vol. 16; nb. 11; (2015); p. 26850 - 26870, View in Reaxys

HernA ndez, Karel; Parella, Teodor; Joglar, Jesffls; Bujons, Jordi; Pohl, Martina; ClapA©s, Pere; Chemistry - A European Journal; vol. 21; nb. 8; (2015); p. 3335 - 3346, View in Reaxys

Patent; Washington State University; Yang, Bin; Laskar, Dhrubojyoti Dey; US2015/99868; (2015); (A1) English, View in Reaxys

CX-15

Patent; Allergan, Inc.; Engles, Charles R.; Fuller, Bryan; Pilcher, Brian Keith; US9107874; (2015); (B2) English, View in Reaxys

Il’ina; Pokrovsky; Mikhalchenko; Korchagina; Volcho; Salakhutdinov; Russian Chemical Bulletin; vol. 64; nb. 9; (2015); p. 2257 - 2260; Izv. Akad. Nauk, Ser. Khim.; nb. 9; (2015); p. 2257 - 2260,4, View in Reaxys

Chen, Chung-Yi; Chang, Fang-Rong; Teng, Che-Ming; Wu, Yang-Chang; Journal of the Chinese Chemical Society; vol. 46; nb. 1; (1999); p. 77 - 86, View in Reaxys; Ren, Xinfeng; Chen, Xiaochuan; Peng, Kun; Xie, Xingang; Xia, Yamu; Pan, Xinfu; Tetrahedron Asymmetry; vol. 13; nb. 16; (2002); p. 1799 - 1804, View in Reaxys; Kim, Ki Hyun; Ha, Sang Keun; Choi, Sang Un; Kim, Sun Yeou; Lee, Kang Ro; Planta Medica; vol. 79; nb. 5; (2013); p. 361 - 364, View in Reaxys; Sedai, Baburam; Diaz-Urrutia, Christian; Baker, R. Tom; Wu, Ruilian; Silks, L. A. Pete; Hanson, Susan K.; ACS Catalysis; vol. 3; nb. 12; (2013); p. 3111 - 3122, View in Reaxys; Kang, Ya-Fei; Liu, Chi-Ming; Kao, Chiu-Li; Chen, Chung-Yi; Molecules; vol. 19; nb. 4; (2014); p. 4235 - 4245, View in Reaxys

HDMB

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys; Jenita, M. Jude; Mohandass; Rajendiran; Journal of Fluorescence; vol. 24; nb. 3; (2014); p. 695 - 707, View in Reaxys

Luo, Yinggang; Zhou, Min; Qi, Huayi; Li, Bogang; Zhang, Guolin; Planta Medica; vol. 71; nb. 11; (2005); p. 1081 - 1084, View in Reaxys; Yao, Jian; Li, Hong; Xu, Ya-Nan; Wang, Qiao-Chun; Qu, Da-Hui; Chemistry - An Asian Journal; vol. 9; nb. 12; (2014); p. 3482 - 3490, View in Reaxys

Wang; Hong; Li; Zhou; Hao; Planta Medica; vol. 66; nb. 6; (2000); p. 511 - 515, View in Reaxys; Chen, FuChi; Peng, Chien-Fang; Tsai, Ian-Lih; Chen, Ih-Sheng; Journal of Natural Products; vol. 68; nb. 9; (2005); p. 1318 - 1323, View in Reaxys; Biannic, Berenger; Bozell, Joseph J.; Elder, Thomas; Green Chemistry; vol. 16; nb. 7; (2014); p. 3635 - 3642, View in Reaxys; Lu, Jianyu; Maezawa, Izumi; Weerasekara, Sahani; Erenler, Ramazan; Nguyen, Tuyen D.T.; Nguyen, James; Swisher, Luxi Z.; Li, Jun; Jin, Lee-Way; Ranjan, Alok; Srivastava, Sanjay K.; Hua, Duy H.; Bioorganic and Medicinal Chemistry Letters; vol. 24; nb. 15; (2014); p. 3392 - 3397, View in Reaxys

Jiang, Jian-An; Du, Jia-Lei; Liao, Dao-Hua; Wang, Zhan-Guo; Ji, Ya-Fei; Tetrahedron Letters; vol. 55; nb. 8; (2014); p. 1406 - 1411, View in Reaxys

2aa

Jiang, Jian-An; Chen, Cheng; Huang, Jian-Gang; Liu, Hong-Wei; Cao, Song; Ji, Ya-Fei; Green Chemistry; vol. 16; nb. 3; (2014); p. 1248 - 1254, View in Reaxys

Sharma, Nandini; Mohanakrishnan, Dinesh; Sharma, Upendra Kumar; Kumar, Rajesh; Richa; Sinha, Arun Kumar; Sahal, Dinkar; European Journal of Medicinal Chemistry; vol. 79; (2014); p. 350 - 368, View in Reaxys

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11t

Kamal, Ahmed; Srinivasa Reddy; Polepalli, Sowjanya; Paidakula, Suresh; Srinivasulu, Vunnam; Ganga Reddy; Jain, Nishant; Shankaraiah, Nagula; Bioorganic and Medicinal Chemistry Letters; vol. 24; nb. 15; (2014); p. 3356 - 3360, View in Reaxys

Oliveira; Baron; Chamayou; Andr-Barrs; Guidetti; Baltas; RSC Advances; vol. 4; nb. 100; (2014); p. 56736 - 56742, View in Reaxys

Zhu, Wufu; Sun, Chengyu; Xu, Shan; Wu, Chunjiang; Wu, Jielian; Xu, Mengze; Zhao, He; Chen, Le; Zeng, Weipeng; Zheng, Pengwu; Bioorganic and Medicinal Chemistry; vol. 22; nb. 24; (2014); p. 6746 6754, View in Reaxys

Man Shing Wong; Zhong Hui Li; Man Fai Shek; Kei Hau Chow; Tao; D'Iorio; Journal of Materials Chemistry; vol. 10; nb. 8; (2000); p. 1805 - 1810, View in Reaxys; Ha; Shin; Lee; Kim; Huh; Yong; Planta Medica; vol. 67; nb. 9; (2001); p. 877 - 880, View in Reaxys; Leu, Yann-Lii; Wang, Yu-Li; Huang, Shih-Chin; Shi, Li-Shian; Chemical and Pharmaceutical Bulletin; vol. 53; nb. 7; (2005); p. 853 - 855, View in Reaxys; Tan, Jianwen; Bednarek, Pawel; Liu, Jikai; Schneider, Bernd; Svatos, Ales; Hahlbrock, Klaus; Phytochemistry; vol. 65; nb. 6; (2004); p. 691 - 699, View in Reaxys; Yang, Xian-Wen; Wang, Jun-Song; Wang, Yue-Hu; Xiao, Hai-Tao; Hu, Xu-Jia; Mu, Shu-Zhen; Yan-Lin, Ma.; Lin, Hua; He, Hong-Ping; Li, Ng; Hao, XiaoJiang; Planta Medica; vol. 73; nb. 5; (2007); p. 496 - 498, View in Reaxys; Cheplogoi, Peter K.; Mulholland, Dulcie A.; Coombes, Philip H.; Randrianarivelojosia, Milijaona; Phytochemistry; vol. 69; nb. 6; (2008); p. 1384 - 1388, View in Reaxys; Toledano, Ana; Serrano, Luis; Balu, Alina Mariana; Luque, Rafael; Pineda, Antonio; Labidi, Jalel; ChemSusChem; vol. 6; nb. 3; (2013); p. 529 - 536, View in Reaxys

Kanagaraj, Kuppusamy; Pitchumani, Kasi; Journal of Organic Chemistry; vol. 78; nb. 2; (2013); p. 744 751, View in Reaxys

Karuturi, Rajesh; Al-Horani, Rami A.; Mehta, Shrenik C.; Gailani, David; Desai, Umesh R.; Journal of Medicinal Chemistry; vol. 56; nb. 6; (2013); p. 2415 - 2428, View in Reaxys; Anand, Preet; Singh, Baldev; Medicinal Chemistry Research; vol. 22; nb. 4; (2013); p. 1648 - 1659, View in Reaxys

Lee, Chien-Hsing; Chen, Hsin-Liang; Hong, Zi-Ling; Hsieh, Chiao-Wei; Juan, Sun-Wen; Huang, JinCherng; Wang, Hui-Min; Chen, Chung-Yi; Chemistry of Natural Compounds; vol. 49; nb. 2; (2013); p. 398 400; Khim. Prir. Soedin.; vol. 2; (2013); p. 335 - 336,2, View in Reaxys

Liberto, Natalia Aparecida; De Paiva Silva, Sarah; De Fatima, Angelo; Fernandes, Sergio Antonio; Tetrahedron; vol. 69; nb. 38; (2013); p. 8245 - 8249, View in Reaxys

Patrick, Donald A.; Bakunov, Stanislav A.; Bakunova, Svetlana M.; Jones, Susan Kilgore; Wenzler, Tanja; Barszcz, Todd; Kumar, Arvind; Boykin, David W.; Werbovetz, Karl A.; Brun, Reto; Tidwell, Richard R.; European Journal of Medicinal Chemistry; vol. 67; (2013); p. 310 - 324, View in Reaxys

Devineni, Subba Rao; Doddaga, Srinivasulu; Donka, Rajasekhar; Chamarthi, Naga Raju; Chinese Chemical Letters; vol. 24; nb. 8; (2013); p. 759 - 763, View in Reaxys

Yang, Xiao-Hui; Zhou, Yong-Hong; Zhang, Ping-Hu; Zhang, Li-Yun; Journal of Heterocyclic Chemistry; vol. 50; nb. 6; (2013); p. 1346 - 1350, View in Reaxys

Chang, Ruijie; Wang, Chunhui; Zeng, Qi; Guan, Bin; Zhang, Weidong; Jin, Huizi; Archives of Pharmacal Research; vol. 36; nb. 11; (2013); p. 1291 - 1301, View in Reaxys

Patra, Amarendra; Mahapatra, Tanusri; Journal of the Indian Chemical Society; vol. 89; nb. 7; (2012); p. 925 - 932, View in Reaxys

Pokhrel, Laxman; Maezawa, Izumi; Nguyen, Thi D. T.; Chang, Kyeong-Ok; Jin, Lee-Way; Hua, Duy H.; Journal of Medicinal Chemistry; vol. 55; nb. 20; (2012); p. 8969 - 8973, View in Reaxys

Ma, Liang; Xie, Caifeng; Ran, Yan; Liang, Xiaolin; Huang, Li; Pei, Heying; Chen, Jinying; Liu, Juan; Sang, Yun; Lai, Huijun; Peng, Aihua; Xiang, Mingli; Wei, Yuquan; Chen, Lijuan; Journal of Medicinal Chemistry; vol. 55; nb. 22; (2012); p. 9958 - 9972, View in Reaxys

Patent; Majeed, Muhammed; Nagabhushanam, Kalyanam; Thomas, Samuel Manoharan; Prakash, Subbalakshmi; US2011/54018; (2011); (A1) English, View in Reaxys

C-1

Patent; Agfa Graphics, N.V.; US7527916; (2009); (B2) English, View in Reaxys

VND3207

Zheng, Hong; Chen, Zhi-Wu; Wang, Lin; Wang, Si-Ying; Yan, Yu-Qian; Wu, Ke; Xu, Qin-Zhi; Zhang, ShiMeng; Zhou, Ping-Kun; European Journal of Pharmaceutical Sciences; vol. 33; nb. 1; (2008); p. 52 - 59, View in Reaxys

10, R=CH3

Kang, Tae-Souk; Jo, Hyang-Ok; Park, Woo-Kyu; Kim, Jong-Pyung; Konishi, Yasuo; Kong, Jae-Yang; Park, No-Sang; Jung, Young-Sik; Bioorganic and Medicinal Chemistry Letters; vol. 18; nb. 5; (2008); p. 1663 - 1667, View in Reaxys

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Baik, Woonphil; Lee, Hyun Joo; Jang, Jung Min; Koo, Sangho; Kim, Byeong Hyo; Journal of Organic Chemistry; vol. 65; nb. 1; (2000); p. 108 - 115, View in Reaxys; Kay; Woolhouse; Gainsford; Haskell; Barnes; McKinnie; Wyss; Journal of Materials Chemistry; vol. 11; nb. 4; (2001); p. 996 - 1002, View in Reaxys; Royer, Daniel; Wong, Yung-Sing; Ple, Sophie; Chiaroni, Angele; Diker, Khalid; Levy, Jean; Tetrahedron; vol. 64; nb. 40; (2008); p. 9607 - 9618, View in Reaxys

SYALD

Clark, Michael; Paulsen, Michael; Smith, Kirk R.; Canuz, Eduardo; Simpson, Christopher D.; Environmental Science and Technology; vol. 41; nb. 10; (2007); p. 3481 - 3487, View in Reaxys

Kamat, Shrivallabh P.; Parab, Sulaksha J.; Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry; vol. 46; nb. 12; (2007); p. 2074 - 2078, View in Reaxys

8, R2=4-OH,3,5(MeO)2

Liu, Ji-Feng; Wilson, Christopher J.; Ye, Ping; Sprague, Kevin; Sargent, Katie; Si, Ying; Beletsky, Galina; Yohannes, Daniel; Ng, Shi-Chung; Bioorganic and Medicinal Chemistry Letters; vol. 16; nb. 3; (2006); p. 686 - 690, View in Reaxys

Tab. 2, entry 12

Wang, Jin-Xian; Wang, Kehu; Zhao, Lianbiao; Li, Hongxia; Fu, Ying; Hu, Yulai; Advanced Synthesis and Catalysis; vol. 348; nb. 10-11; (2006); p. 1262 - 1270, View in Reaxys

Leu, Yann-Lii; Hwang, Tsong-Long; Chung, Yu-Ming; Hong, Pao-Yun; Chemical and Pharmaceutical Bulletin; vol. 54; nb. 7; (2006); p. 1063 - 1066, View in Reaxys

Arimitsu, Satoru; Hammond, Gerald B.; Journal of Organic Chemistry; vol. 71; nb. 22; (2006); p. 8665 8668, View in Reaxys

subs., Tab. 1, entry 16

Rudrawar, Santosh; Besra, Ram C.; Chakraborti, Asit K.; Synthesis; nb. 16; (2006); p. 2767 - 2771, View in Reaxys

scheme3, start

Mateo, Carmen; Perez-Melero, Concepcion; Pelaez, Rafael; Medarde, Manuel; Tetrahedron Letters; vol. 46; nb. 41; (2005); p. 7055 - 7057, View in Reaxys

educt of tab 1, entr 6

Besra, Ram C.; Rudrawar, Santosh; Chakraborti, Asit K.; Tetrahedron Letters; vol. 46; nb. 37; (2005); p. 6213 - 6217, View in Reaxys

11a

Liu, Ji-Feng; Ye, Ping; Sprague, Kevin; Sargent, Katie; Yohannes, Daniel; Baldino, Carmen M.; Wilson, Christopher J.; Ng, Shi-Chung; Organic Letters; vol. 7; nb. 15; (2005); p. 3363 - 3366, View in Reaxys

Lapeyre, Caroline; Delomenede, Melanie; Bedos-Belval, Florence; Duran, Hubert; Negre-Salvayre, Anne; Baltas, Michel; Journal of Medicinal Chemistry; vol. 48; nb. 26; (2005); p. 8115 - 8124, View in Reaxys

Lee, Tzong-Huei; Chiou, Jong-Liang; Lee, Ching-Kuo; Kuo, Yueh-Hsiung; Journal of the Chinese Chemical Society; vol. 52; nb. 4; (2005); p. 833 - 841, View in Reaxys

Wu, Pei-Lin; Wu, Tian-Shung; He, Cai-Xia; Su, Chia-Hao; Lee, Kuo-Hsiung; Chemical and Pharmaceutical Bulletin; vol. 53; nb. 1; (2005); p. 56 - 59, View in Reaxys

I (X=H, R', R''=OMe)

Youssef, Khairia M.; El-Sherbeny, Magda A.; El-Shafie, Faiza S.; Farag, Hassan A.; Al-Deeb, Omar A.; Awadalla, Sit Albanat A.; Archiv der Pharmazie; vol. 337; nb. 1; (2004); p. 42 - 54, View in Reaxys

Wang, Eng-Chi; Huang, Keng-Shiang; Chen, Hsing-Ming; Wu, Chung-Chin; Lin, Gwo-Jiun; Journal of the Chinese Chemical Society; vol. 51; nb. 3; (2004); p. 619 - 627, View in Reaxys

Manjula; Vittal Rao; Neelakantan, Parvathi; Synthetic Communications; vol. 34; nb. 14; (2004); p. 2665 2671, View in Reaxys

IIIs

Kozlov; Gusak; Tereshko; Firgang; Shashkov; Russian Journal of Organic Chemistry; vol. 40; nb. 8; (2004); p. 1181 - 1186, View in Reaxys

Jeong, Tae-Sook; Kim, Ju-Ryoung; Kim, Kyung Soon; Cho, Kyung-Hyun; Bae, Ki-Hwan; Lee, Woo Song; Bioorganic and Medicinal Chemistry; vol. 12; nb. 15; (2004); p. 4017 - 4023, View in Reaxys

compound VI

Patent; EXEGENICS, INC.; WO2004/12506; (2004); (A2) English, View in Reaxys

IIc

Ivanova; Reutskaya; Gusarova; Medvedeva; Afonin; Ushakov; Tatarinova; Trofimov; Russian Journal of General Chemistry; vol. 73; nb. 9; (2003); p. 1354 - 1357, View in Reaxys

Chang, Keng-Chia; Duh, Chang-Yih; Chen, Ih-Sheng; Tsai, Ian-Lih; Planta Medica; vol. 69; nb. 7; (2003); p. 667 - 672, View in Reaxys

Kim, Hoon; Ralph, John; Lu, Fachuang; Ralph, Sally A.; Boudet, Alain-M.; MacKay, John J.; Sederoff, Ronald R.; Ito, Takashi; Kawai, Shingo; Ohashi, Hideo; Higuchi, Takayoshi; Organic and Biomolecular Chemistry; vol. 1; nb. 2; (2003); p. 268 - 281, View in Reaxys

14r

Sakakibara, Norikazu; Suzuki, Shiro; Umezawa, Toshiaki; Shimada, Mikio; Organic and biomolecular chemistry; vol. 1; nb. 14; (2003); p. 2474 - 2485, View in Reaxys

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Takaki, Ken; Shimasaki, Yohei; Shishido, Tetsuya; Takehira, Katsuomi; Bulletin of the Chemical Society of Japan; vol. 75; nb. 2; (2002); p. 311 - 317, View in Reaxys

Tab.1, Entr.8, Product

Zubaidha; Bhosale; Hashmi; Tetrahedron Letters; vol. 43; nb. 40; (2002); p. 7277 - 7279, View in Reaxys

Kozlov; Basalaeva; Skakovskaya; Russian Journal of General Chemistry; vol. 72; nb. 8; (2002); p. 1238 1242, View in Reaxys

Nolte, Christopher G.; Schauer, James J.; Cass, Glen R.; Simoneit, Bernd R.T.; Environmental Science and Technology; vol. 35; nb. 10; (2001); p. 1912 - 1919, View in Reaxys

Ley, Jakob P; Bertram, Heinz-Juergen; Bioorganic and Medicinal Chemistry; vol. 9; nb. 7; (2001); p. 1879 1885, View in Reaxys

Tuck, Kellie L.; Hayball, Peter J.; Journal of Labelled Compounds and Radiopharmaceuticals; vol. 44; nb. 14; (2001); p. 1005 - 1012, View in Reaxys

aldehyde to XXIX

Gusak; Tereshko; Kozlov; Russian Journal of Organic Chemistry; vol. 37; nb. 10; (2001); p. 1495 - 1502, View in Reaxys

SAL

Van den Worm, Edwin; Beukelman, Cees J.; Van den Berg, Albert J.J.; Kroes, Burt H.; Labadie, Rudi P.; Van Dijk, Hans; European Journal of Pharmacology; vol. 433; nb. 2-3; (2001); p. 225 - 230, View in Reaxys

Fig. 4; 2nd in 3rd line

Pomes; Larive; Thurman; Green; Orem; Rostad; Coplen; Cutak; Dixon; Environmental Science and Technology; vol. 34; nb. 20; (2000); p. 4278 - 4286, View in Reaxys

IV,R=3,5(MeO)2-4OHC6H

Kozlov; Popova; Yakubovich; Russian Journal of Organic Chemistry; vol. 36; nb. 11; (2000); p. 1667 1670, View in Reaxys

Kim, Hoon; Ralph, John; Yahiaoui, Nabila; Pean, Michel; Boudet, Alain-M.; Organic Letters; vol. 2; nb. 15; (2000); p. 2197 - 2200, View in Reaxys

Bebbington, David; Monck, Nathaniel J. T.; Gaur, Suneel; Palmer, Alan M.; Benwell, Karen; Harvey, Victoria; Malcolm, Craig S.; Porter, Richard H. P.; Journal of Medicinal Chemistry; vol. 43; nb. 15; (2000); p. 2779 - 2782, View in Reaxys

product, entry 6

Kamal, Ahmed; Ramana, K. Venkata; Arifuddin; Chemistry Letters; nb. 8; (1999); p. 827 - 828, View in Reaxys

3(R1=OH,R2=R3 =OMe,R4=H)

Kato, Tatsuya; Ozaki, Tomokazu; Tamura, Kazuhiko; Suzuki, Yoshiyuki; Akima, Michitaka; Ohi, Nobuhiro; Journal of Medicinal Chemistry; vol. 42; nb. 16; (1999); p. 3134 - 3146, View in Reaxys

4-HO-3,5(MeO)2C6H4CHO

Grosche, Philipp; Hoeltzel, Alexandra; Walk, Tilmann B.; Trautwein, Axel W.; Jung, Guenther; Synthesis; nb. 11; (1999); p. 1961 - 1970, View in Reaxys

Jinno, Shuji; Okita, Takaaki; Chemical and Pharmaceutical Bulletin; vol. 46; nb. 11; (1998); p. 1688 - 1694, View in Reaxys

Patent-Specific Data (14) Prophetic ComLocation in Patent References pound Patent; Ogawa Co., Ltd.; Hatano, Kosuke; (10 pag.); JP2017/43543; (2017); (A) Japanese, View in Reaxys Patent; Shantou University Medical School; Pan Ying; Zheng Jinhong; Chen Cheng; (12 pag.); CN106496052; (2017); (A) Chinese, View in Reaxys Patent; Zunyi Medical College; ZHANG, LEI; WANG, JING; YAO, QIZHENG; (10 pag.); CN104000817; (2016); (B) Chinese, View in Reaxys Page/Page column

Patent; HOFFMANN-LA ROCHE INC.; Gobbi, Luca; Knust, Henner; Koblet, Andreas; US2015/157739; (2015); (A1) English, View in Reaxys Patent; BASF SE; EBEL, KLAUS; RUDENAUER, STEFAN; (12 pag.); JP5816260; (2015); (B2) Japanese, View in Reaxys

Page/Page column

Patent; Ajinomoto Co., Inc.; TAKAHASHI, Daisuke; EP2518041; (2012); (A1) English, View in Reaxys; Patent; INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES; Shi, Jiangong; Zhang, Jianjun; Yue, Zhenggang; Li, Min; Zhu, Chenggen; Zhang, Ying; Zi, Jiachen; Wang, Yafang; Fan, Xiaona; Xu, Ruiming; Lin, Sheng; Li, Yan; Yang, Yongchun; Sheng, Li; US2013/45942; (2013); (A1) English, View in Reaxys; Patent; ZAKRYTOE AKTSIONERNOE OBSCHSHESTVO "VERTEX"; Veselkina, Olga Sergejevna; Viktorov, Nikolay Borisovich; Petrishchev, Nikolay Ni-

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kolaevich; Poplavskaya, Yuliya Vyacheslavovna; US2013/267707; (2013); (A1) English, View in Reaxys; Patent; RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter Ronald; US2013/281397; (2013); (A1) English, View in Reaxys; Patent; RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.; US2013/281398; (2013); (A1) English, View in Reaxys; Patent; ROLIC AG; Lincker, Frederic; Bury S. Pires, Izabela; Chappellet, Sabrina; Scandiucci De Freitas, Patricia; Ibn-Elhaj, Mohammed; Tang, Qian; Palika, Satish; Hoshino, Masato; Eckert, Jean-Francois; US2014/192305; (2014); (A1) English, View in Reaxys Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; GOBBI, Luca; KNUST, Henner; KOBLET, Andreas; WO2014/26881; (2014); (A1) English, View in Reaxys Patent; Majeed, Muhammed; Nagabhushanam, Kalyanam; Thomas, Samuel Manoharan; Prakash, Subbalakshmi; US2011/54018; (2011); (A1) English, View in Reaxys Patent; BASF SE; US2011/245544; (2011); (A1) English, View in Reaxys Patent; Shibata, Hiroyuki; Iwabuchi, Yoshiharu; Ohori, Hisatsugu; Yamakoshi, Hiroyuki; Kakudo, Yuichi; US2010/152493; (2010); (A1) English, View in Reaxys prophetic product

Page/page column 47

Patent; L'OREAL; WO2009/40354; (2009); (A1) English, View in Reaxys Patent; Novozymes A/S; EP1030561; (2006); (B1) English, View in Reaxys Patent; OAKY NATURAL CO., LTD; WANG, Sung-Ho; WO2005/44247; (2005); (A1) English, View in Reaxys Patent; JANSSEN PHARMACEUTICA N.V.; WO2004/7498; (2004); (A2) English, View in Reaxys

Druglikeness (1) 1 of 1

LogP

0.874

H Bond Donors

H Bond Acceptors

Rotatable Bonds

TPSA

55.76

Lipinski Number

Veber Number

Derivative (9) Comment (Derivative) Na-Salz: UVMax.: 370 nm, 254 nm, 218 nm (A. + NaOH)

References Santavy et al.; Acta Universitatis Palackianae Olomucensis, Facultatis Medicae, Supplementum; vol. 13; (1973); p. 23; Chem.Abstr.; vol. 81; nb. 25219, View in Reaxys

2,4-Dinitrophenyl- Shimizu et al.; Agricultural and Biological Chemistry; vol. 34; (1970); p. 437,439, View in Reaxys hydrazon: F: 252grad Na-Salz, IR

Bullock; Jones; Journal of the Chemical Society [Section] A: Inorganic, Physical, Theoretical; (1970); p. 2472, View in Reaxys

2,4-Dinitrophenyl- Yang; Chow; Journal of the Chinese Chemical Society (Taipei, Taiwan); vol. 15; (1968); p. 97,99,100,101, hydrazon: F: View in Reaxys 238-238.5grad(un korr.), UV, IR as 4-phenyl semi- Milletti; Annali di Chimica (Rome, Italy); vol. 45; (1955); p. 1211,1213, View in Reaxys carbazone (mp: 212-213 degree ) as 3-nitro-benKratzl; Billek; Monatshefte fuer Chemie; vol. 85; (1954); p. 845,854, View in Reaxys zoylhydrazone (mp: 205 degree )

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2017-10-08 12:35:19

4-nitro-phenylhydrazone(mp: 222 degree )

Imaki et al.; Nippon Nogei Kagaku Kaishi; vol. 20; (1944); p. 289,292; Chem.Abstr.; (1949); p. 1743, View in Reaxys

2.4-dinitro-phenyl- Pyle; Brickman; Hibbert; Journal of the American Chemical Society; vol. 61; (1939); p. 2198, hydrazone(mp: View in Reaxys 235.5-236.5 degree ) as p-nitro-phenylhydrazone of mp: 216-217 degree

Mauthner; Journal fuer Praktische Chemie (Leipzig); vol. <2> 92; (1915); p. 200, View in Reaxys

Melting Point (38) 1 of 38

Melting Point [°C]

113 - 114

Sribuhom, Thurdpong; Sriphana, Uraiwan; Thongsri, Yordhathai; Yenjai, Chavi; Phytochemistry Letters; vol. 11; (2015); p. 80 - 84, View in Reaxys 2 of 38

Melting Point [°C]

110 - 112

Guo, Ying; Ji, Si-Zhe; Chen, Cheng; Liu, Hong-Wei; Zhao, Jian-Hong; Zheng, Yu-Lin; Ji, Ya-Fei; Research on Chemical Intermediates; vol. 41; nb. 11; (2015); p. 8651 - 8664, View in Reaxys 3 of 38

Melting Point [°C]

108 - 110

Location

supporting information

Jiang, Jian-An; Chen, Cheng; Huang, Jian-Gang; Liu, Hong-Wei; Cao, Song; Ji, Ya-Fei; Green Chemistry; vol. 16; nb. 3; (2014); p. 1248 - 1254, View in Reaxys; Jiang, Jian-An; Du, Jia-Lei; Liao, Dao-Hua; Wang, Zhan-Guo; Ji, Ya-Fei; Tetrahedron Letters; vol. 55; nb. 8; (2014); p. 1406 - 1411, View in Reaxys; Jiang, Jian-An; Du, Jia-Lei; Wang, Zhan-Guo; Zhang, Zhong-Nan; Xu, Xi; Zheng, Gan-Lin; Ji, Ya-Fei; Tetrahedron Letters; vol. 55; nb. 10; (2014); p. 1677 - 1681, View in Reaxys; Jiang, Jian-An; Du, Jia-Lei; Zhang, Zhong-Nan; Zhai, Jiao-Jiao; Ji, YaFei; Synthetic Communications; vol. 44; nb. 10; (2014); p. 1430 - 1440, View in Reaxys 4 of 38

Melting Point [°C]

109 - 111

Wang, Chun-Hui; Wei, Pan-Lei; Guan, Bin; Jin, Hui-Zi; Zhang, Wei-Dong; Chemistry of Natural Compounds; vol. 50; nb. 1; (2014); p. 142 - 143; Khim. Prir. Soedin.; nb. 1; (2014); p. 126 - 127,2, View in Reaxys 5 of 38

Melting Point [°C]

110 - 113

Oliveira; Baron; Chamayou; Andr-Barrs; Guidetti; Baltas; RSC Advances; vol. 4; nb. 100; (2014); p. 56736 56742, View in Reaxys 6 of 38

Melting Point [°C]

109 - 111

Location

supporting information

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys 7 of 38

Melting Point [°C]

111 - 112

Ding, Junwei; Qi, Rongwei; Zhou, Haitang; Jiao, Bin; Xia, Yamu; Journal of Chemical Research; vol. 35; nb. 9; (2011); p. 519 - 521, View in Reaxys 8 of 38

Melting Point [°C]

107 - 108

Solvent (Melting Point)

hexane

Tripathi; Sama; Taneja; Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry; vol. 49; nb. 3; (2010); p. 379 - 381, View in Reaxys 9 of 38

Melting Point [°C]

110 - 112

Lee, Hak-Ju; Khan; Kang, Ha-Young; Choi, Don-Ha; Mi-Jin, Park; Hyun-Jung, Lee; Chemistry of Natural Compounds; vol. 46; nb. 2; (2010); p. 289 - 290, View in Reaxys 10 of 38

Melting Point [°C]

113 - 115

Melting Point [°C]

112 - 114

Solvent (Melting Point)

CH2Cl2; hexane

Duarte, Noelia; Ferreira, Maria-Jose U.; Organic Letters; vol. 9; nb. 3; (2007); p. 489 - 492, View in Reaxys

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12 of 38

Melting Point [°C]

114 - 116

Ciaramitaro,D.; Steelink,C.; Phytochemistry (Elsevier); vol. 14; (1975); p. 543 - 552, View in Reaxys; Lee, TzongHuei; Chiou, Jong-Liang; Lee, Ching-Kuo; Kuo, Yueh-Hsiung; Journal of the Chinese Chemical Society; vol. 52; nb. 4; (2005); p. 833 - 841, View in Reaxys 13 of 38

Melting Point [°C]

113 - 114

Hansson; Wickberg; Synthesis; (1976); p. 191, View in Reaxys; Lehrer; Stevenson; Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999); (1974); p. 1165, View in Reaxys; Ren, Xinfeng; Chen, Xiaochuan; Peng, Kun; Xie, Xingang; Xia, Yamu; Pan, Xinfu; Tetrahedron Asymmetry; vol. 13; nb. 16; (2002); p. 1799 - 1804, View in Reaxys; Su, Ying; Ren, Xin-Feng; She, Xue-Gong; Pan, Xin-Fu; Journal of the Chinese Chemical Society; vol. 51; nb. 6; (2004); p. 1333 - 1337, View in Reaxys 14 of 38

Melting Point [°C]

106 - 108

Wang, Ying; Yang, Min; Yuan, Cheng-Shan; Han, Yi-Feng; Jia, Zhong-Jian; Pharmazie; vol. 58; nb. 8; (2003); p. 596 - 598, View in Reaxys 15 of 38

Melting Point [°C]

110 - 112

Takaki, Ken; Shimasaki, Yohei; Shishido, Tetsuya; Takehira, Katsuomi; Bulletin of the Chemical Society of Japan; vol. 75; nb. 2; (2002); p. 311 - 317, View in Reaxys 16 of 38

Melting Point [°C]

112 - 114

Patent; Gulf Oil Corp., Pittsburgh, Pa (V. St. A.); DE2617585; (1976); Chem.Abstr.; vol. 86; nb. 55159, View in Reaxys; Lee, Ching-Kuo; Chang, Ming-Huey; Journal of the Chinese Chemical Society; vol. 47; nb. 3; (2000); p. 555 - 560, View in Reaxys 17 of 38

Melting Point [°C]

113 - 114

Solvent (Melting Point)

methanol

Deng; Newman; Hecht; Journal of Natural Products; vol. 63; nb. 9; (2000); p. 1269 - 1272, View in Reaxys 18 of 38

Melting Point [°C]

108 - 110

Solvent (Melting Point)

CHCl3

Chen, Chung-Yi; Chang, Fang-Rong; Teng, Che-Ming; Wu, Yang-Chang; Journal of the Chinese Chemical Society; vol. 46; nb. 1; (1999); p. 77 - 86, View in Reaxys 19 of 38

Melting Point [°C]

107

Gutierrez, Alicia B.; Herz, Werner; Phytochemistry (Elsevier); vol. 27; nb. 12; (1988); p. 3871 - 3874, View in Reaxys 20 of 38

Melting Point [°C]

111

Solvent (Melting Point)

petroleum ether

Borges-Del-Castillo, Juan; Bradley-Delso, Antonio; Manresa-Ferrero, Ma. Teresa; Vazquez-Bueno, Purificacion; Rodriguez-Luis, Francisco; Phytochemistry (Elsevier); vol. 22; nb. 3; (1983); p. 782 - 783, View in Reaxys 21 of 38

Melting Point [°C]

110 - 112

Solvent (Melting Point)

CHCl3; hexane

Herz,W.; Kumar,N.; Phytochemistry (Elsevier); vol. 20; (1980); p. 247, View in Reaxys 22 of 38

Melting Point [°C]

113

Lundquist,K.; Acta Chemica Scandinavica (1947-1973); vol. 27; (1973); p. 2597 - 2606, View in Reaxys; Pauly; Strassberger; Chemische Berichte; vol. 62; (1929); p. 2279, View in Reaxys; Graebe; Martz; Chemische Berichte; vol. 36; (1903); p. 1033, View in Reaxys; Klemola; Suomen Kemistilehti B; vol. 41; nb. 3; (1968); p. 83, View in Reaxys 23 of 38

Melting Point [°C]

118

Santavy et al.; Acta Universitatis Palackianae Olomucensis, Facultatis Medicae, Supplementum; vol. 13; (1973); p. 23; Chem.Abstr.; vol. 81; nb. 25219, View in Reaxys 24 of 38

Melting Point [°C]

108 - 110

Da Silva et al.; Phytochemistry (Elsevier); vol. 12; (1973); p. 471,472, View in Reaxys 25 of 38

Melting Point [°C]

112 - 113

Solvent (Melting Point)

petroleum ether

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2017-10-08 12:35:19

Claus,P. et al.; Monatshefte fuer Chemie; vol. 103; (1972); p. 1178 - 1193, View in Reaxys 26 of 38

Melting Point [°C]

111 - 112

Kratzl,K.; Vierhapper,F.W.; Monatshefte fuer Chemie; vol. 102; (1971); p. 425 - 430, View in Reaxys 27 of 38

Melting Point [°C]

115 - 117

Solvent (Melting Point)

H2O

Milletti; Annali di Chimica (Rome, Italy); vol. 45; (1955); p. 1211,1213, View in Reaxys 28 of 38

Melting Point [°C]

114

Solvent (Melting Point)

H2O

Manske; Ledingham; Holmes; Canadian Journal of Research, Section B: Chemical Sciences; vol. 23; (1945); p. 100,102, View in Reaxys 29 of 38

Melting Point [°C]

114

Solvent (Melting Point)

petroleum ether

Manske; Ledingham; Holmes; Canadian Journal of Research, Section B: Chemical Sciences; vol. 23; (1945); p. 100,102, View in Reaxys 30 of 38

Melting Point [°C]

114

Solvent (Melting Point)

aq. ethanol

Manske; Ledingham; Holmes; Canadian Journal of Research, Section B: Chemical Sciences; vol. 23; (1945); p. 100,102, View in Reaxys 31 of 38

Melting Point [°C]

114

Solvent (Melting Point)

aq. methanol

Manske; Ledingham; Holmes; Canadian Journal of Research, Section B: Chemical Sciences; vol. 23; (1945); p. 100,102, View in Reaxys 32 of 38

Melting Point [°C]

115

Solvent (Melting Point)

H2O

Imaki et al.; Nippon Nogei Kagaku Kaishi; vol. 20; (1944); p. 289,292; Chem.Abstr.; (1949); p. 1743, View in Reaxys 33 of 38

Melting Point [°C]

115

Solvent (Melting Point)

petroleum ether

Imaki et al.; Nippon Nogei Kagaku Kaishi; vol. 20; (1944); p. 289,292; Chem.Abstr.; (1949); p. 1743, View in Reaxys 34 of 38

Melting Point [°C]

115

Solvent (Melting Point)

aq. ethanol

Imaki et al.; Nippon Nogei Kagaku Kaishi; vol. 20; (1944); p. 289,292; Chem.Abstr.; (1949); p. 1743, View in Reaxys 35 of 38

Melting Point [°C]

115

Solvent (Melting Point)

aq. methanol

Imaki et al.; Nippon Nogei Kagaku Kaishi; vol. 20; (1944); p. 289,292; Chem.Abstr.; (1949); p. 1743, View in Reaxys 36 of 38

Melting Point [°C]

112 - 113

Spaeth; Monatshefte fuer Chemie; vol. 41; (1920); p. 278, View in Reaxys 37 of 38

Melting Point [°C]

113

Solvent (Melting Point)

petroleum ether

Mauthner; Journal fuer Praktische Chemie (Leipzig); vol. <2> 92; (1915); p. 200, View in Reaxys 38 of 38

Melting Point [°C]

111.5

Koerner; Gazzetta Chimica Italiana; vol. 18; (1888); p. 215, View in Reaxys Boiling Point (1) Boiling Point [°C]

Pressure (Boiling Point) [Torr]

References

13/130

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192 - 193

Mauthner; Journal fuer Praktische Chemie (Leipzig); vol. <2> 92; (1915); p. 200, View in Reaxys

Adsorption (MCS) (1) 1 of 1

Description (Adsorption (MCS))

Adsorption

Solvent (Adsorption (MCS))

chloroform

Partner (Adsorption (MCS))

(3-aminopropyl)trimethoxysilane-functionalized mesoporous pore-expanded silica

Drese, Jeffrey H.; Talley, Anne D.; Jones, Christopher W.; ChemSusChem; vol. 4; nb. 3; (2011); p. 379 - 385, View in Reaxys Association (MCS) (1) 1 of 1

Description (Association Stability constant of the complex with ... (MCS)) Partner (Association (MCS))

β-cyclodextrin

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys Chromatographic Data (7) Chromatographic Original string data

Location

References

HPLC (High performance liquid chromatography)

Mena, Pedro; Calani, Luca; Dall'Asta, Chiara; Galaverna, Gianni; Garcia-Viguera, Cristina; Bruni, Renato; Crozier, Alan; Del Rio, Daniele; Molecules; vol. 17; nb. 12; (2012); p. 14821 - 14840, View in Reaxys; Toledano, Ana; Serrano, Luis; Balu, Alina Mariana; Luque, Rafael; Pineda, Antonio; Labidi, Jalel; ChemSusChem; vol. 6; nb. 3; (2013); p. 529 - 536, View in Reaxys; Toledano, Ana; Serrano, Luis; Labidi, Jalel; Pineda, Antonio; Balu, Alina Mariana; Luque, Rafael; ChemCatChem; vol. 5; nb. 4; (2013); p. 977 - 985, View in Reaxys; Wittayalai, Sawangjitt; Mahidol, Chulabhorn; Prachyawarakorn, Vilailak; Prawat, Hunsa; Ruchirawat, Somsak; Phytochemistry; vol. 99; (2014); p. 121 - 126, View in Reaxys; Lu, Rui-Li; Hu, Feng-Lin; Bao, Guan-Hu; Chemistry of Natural Compounds; vol. 50; nb. 1; (2014); p. 65 - 67; Khim. Prir. Soedin.; nb. 1; (2014); p. 62 - 63,2, View in Reaxys; Palomero, Felipe; Bertani, Paolo; Fernández De Simón, Brígida; Cadahía, Estrella; Benito, Santiago; Morata, Antonio; Suárez-Lepe, José A.; Food Chemistry; vol. 171; (2014); p. 212 - 223, View in Reaxys; Chen, Shao-Dan; Lu, Chuan-Jian; Zhao, Rui-Zhi; Molecules; vol. 20; nb. 1; (2015); p. 1594 - 1609, View in Reaxys; Wang, Yan-Ming; Zhao, Jian-Qiang; Zhou, Shuang-Yan; Yang, Jun-Li; Yao, XiaoJun; Tao, Yan-Duo; Mei, Li-Juan; Shi, Yan-Ping; Tetrahedron; vol. 72; nb. 32; (2016); p. 4910 - 4917, View in Reaxys; Sang, Xia-Nan; Chen, Shao-Fei; An, Xiao; Chen, Gang; Wang, Hai-Feng; Pei, Yue-Hu; Journal of Asian Natural Products Research; vol. 19; nb. 5; (2017); p. 436 - 443, View in Reaxys

GC (Gas chromatography)

Karimov; Aisa; Chemistry of Natural Compounds; vol. 48; nb. 5; (2012); p. 903 - 905; Khim. Prir. Soedin.; nb. 5; (2012); p. 800 801,2, View in Reaxys; Saitta, Marcello; La Torre, Giovanna Loredana; Potorti, Angela Giorgia; Di Bella, Giuseppa; Dugo, Giacomo; Journal of the American Oil Chemists' Society; vol. 91; nb. 9; (2014); p. 1595 - 1603,9, View in Reaxys; Palomero, Felipe; Bertani, Paolo; Fernández De Simón, Brígida; Cadahía, Estrella; Benito, Santiago; Morata, Antonio; Suárez-Lepe, José A.; Food Chemistry; vol. 171; (2014); p. 212 - 223, View in Reaxys; Wang, Yongsheng; Yang, Fang; Liu, Zhi-hua; Yuan, Lu; Li, Gang; Catalysis Communications; vol. 67; (2015); p. 49 - 53; Art.No: 4280, View in Reaxys; Mathew, Sindhu; Zakaria, Zainul Akmar; Musa, Nur Fashya; Process Biochemistry; vol. 50; nb. 11; (2015); p. 1985 1992, View in Reaxys; Jerkovic, Igor; Tuberoso, Carlo I. G.; Marijanovic, Zvonimir; Kranjac, Marina; Malenica-Staver; Chemistry and Biodiversity; vol. 12; nb. 7; (2015); p. 1047 - 1056, View in Reaxys; Xu, Guan-Ling; Geng, Di; Xie, Meng; Teng, Kai-

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supporting information

LC (Liquid chromatography)

Sturgeon, Matthew R.; O'Brien, Marykate H.; Ciesielski, Peter N.; Katahira, Rui; Kruger, Jacob S.; Chmely, Stephen C.; Hamlin, Jessica; Lawrence, Kelsey; Hunsinger, Glendon B.; Foust, Thomas D.; Baldwin, Robert M.; Biddy, Mary J.; Beckham, Gregg T.; Green Chemistry; vol. 16; nb. 2; (2014); p. 824 - 835, View in Reaxys; Nishiwaki-Akine, Yuri; Watanabe, Takashi; Green Chemistry; vol. 16; nb. 7; (2014); p. 3569 - 3579, View in Reaxys; Deuss, Peter J.; Scott, Martin; Tran, Fanny; Westwood, Nicholas J.; De Vries, Johannes G.; Barta, Katalin; Journal of the American Chemical Society; vol. 137; nb. 23; (2015); p. 7456 - 7467, View in Reaxys; Wang, Yuan-Ying; Ling, Li-Li; Jiang, Hong; Green Chemistry; vol. 18; nb. 14; (2016); p. 4032 - 4041, View in Reaxys; Yin, Hui-Shuang; Liu, Hua-Min; Liu, Yu-Lan; Molecules; vol. 22; nb. 6; (2017); Art.No: 890, View in Reaxys Barnaba; Dellacassa; Nicolini; Nardin; Malacarne; Larcher; Food Chemistry; vol. 206; (2016); p. 260 - 266, View in Reaxys; Liu, Meng-Hua; Zhang, Qi; Zhang, Yuan-He; Lu, Xian-Yuan; Fu, WeiMing; He, Jing-Yu; Molecules; vol. 21; nb. 9; (2016); Art.No: 1204, View in Reaxys

TLC (Thin layer chromatography)

supporting information

Kärkäs, Markus D.; Bosque, Irene; Matsuura, Bryan S.; Stephenson, Corey R. J.; Organic Letters; vol. 18; nb. 19; (2016); p. 5166 5169, View in Reaxys

GC (Gas chroma- Retention tography) time/min 23.87

Paragraph 0169

Patent; Washington State University; Yang, Bin; Laskar, Dhrubojyoti Dey; US2015/99868; (2015); (A1) English, View in Reaxys

Ion chromatography Crystal Property Description (14) Colour & Other Location Properties

Dolan, Jeffrey A.; Sathitsuksanoh, Noppadon; Rodriguez, Katia; Simmons, Blake A.; Frazier, Charles E.; Renneckar, Scott; RSC Advances; vol. 5; nb. 82; (2015); p. 67267 - 67276, View in Reaxys References

yellow

Zhu, Jia-Xian; Qin, Jiang-Jiang; Zhang, Fei; Chang, Rui-Jie; Ren, Jie; Cheng, Xiang-Rong; Zeng, Qi; Jin, Hui-Zi; Zhang, Wei-Dong; Chemistry of Natural Compounds; vol. 49; nb. 2; (2013); p. 383 - 387; Khim. Prir. Soedin.; vol. 49; nb. 2; (2013); p. 324 - 327,4, View in Reaxys; Chang, Ruijie; Wang, Chunhui; Zeng, Qi; Guan, Bin; Zhang, Weidong; Jin, Huizi; Archives of Pharmacal Research; vol. 36; nb. 11; (2013); p. 1291 - 1301, View in Reaxys; Guo, Ying; Ji, Si-Zhe; Chen, Cheng; Liu, Hong-Wei; Zhao, Jian-Hong; Zheng, Yu-Lin; Ji, Ya-Fei; Research on Chemical Intermediates; vol. 41; nb. 11; (2015); p. 8651 - 8664, View in Reaxys; Chi, Jun; Li, Bao-Cai; Yang, BoTao; Zhang, Mi; Journal of the Chemical Society of Pakistan; vol. 38; nb. 3; (2016); p. 533 - 537, View in Reaxys

white

Sribuhom, Thurdpong; Sriphana, Uraiwan; Thongsri, Yordhathai; Yenjai, Chavi; Phytochemistry Letters; vol. 11; (2015); p. 80 - 84, View in Reaxys; Hong, Seong Su; Choi, Chun Whan; Choi, Yun-Hyeok; Oh, Joa Sub; Phytochemistry Letters; vol. 17; (2016); p. 152 - 157, View in Reaxys

15/130

2017-10-08 12:35:19

white

supporting information

colourless

Kärkäs, Markus D.; Bosque, Irene; Matsuura, Bryan S.; Stephenson, Corey R. J.; Organic Letters; vol. 18; nb. 19; (2016); p. 5166 - 5169, View in Reaxys Kang, Ya-Fei; Liu, Chi-Ming; Kao, Chiu-Li; Chen, Chung-Yi; Molecules; vol. 19; nb. 4; (2014); p. 4235 - 4245, View in Reaxys; Wang, Chun-Hui; Wei, Pan-Lei; Guan, Bin; Jin, Hui-Zi; Zhang, Wei-Dong; Chemistry of Natural Compounds; vol. 50; nb. 1; (2014); p. 142 - 143; Khim. Prir. Soedin.; nb. 1; (2014); p. 126 - 127,2, View in Reaxys; Wang, Huan-Qin; Peng, Chao-Zhong; Chen, Ye-Gao; Chemistry of Natural Compounds; vol. 51; nb. 6; (2015); p. 1167 - 1168; Khim. Prir. Soedin.; vol. 6; (2015); p. 1004 - 1005,2, View in Reaxys

yellow

supporting information

Jiang, Jian-An; Chen, Cheng; Huang, Jian-Gang; Liu, Hong-Wei; Cao, Song; Ji, YaFei; Green Chemistry; vol. 16; nb. 3; (2014); p. 1248 - 1254, View in Reaxys; Jiang, Jian-An; Du, Jia-Lei; Liao, Dao-Hua; Wang, Zhan-Guo; Ji, Ya-Fei; Tetrahedron Letters; vol. 55; nb. 8; (2014); p. 1406 - 1411, View in Reaxys; Jiang, Jian-An; Du, Jia-Lei; Wang, Zhan-Guo; Zhang, Zhong-Nan; Xu, Xi; Zheng, Gan-Lin; Ji, Ya-Fei; Tetrahedron Letters; vol. 55; nb. 10; (2014); p. 1677 - 1681, View in Reaxys; Jiang, Jian-An; Du, JiaLei; Zhang, Zhong-Nan; Zhai, Jiao-Jiao; Ji, Ya-Fei; Synthetic Communications; vol. 44; nb. 10; (2014); p. 1430 - 1440, View in Reaxys

white

Page/Page column 47

Patent; FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC; UNIVERSITY OF RHODE ISLAND; SEERAM, Navindra, P.; LI, Liya; BELAND, Genevieve; BARBEAU, Julie; WO2012/21981; (2012); (A1) English, View in Reaxys

colourless

supporting information

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys

white

Shirali, Anupama; Sriram, Madhavi; Hall, John J.; Nguyen, Benson L.; Guddneppanavar, Rajsekhar; Hadimani, Mallinath B.; Ackley, J. Freeland; Siles, Rogelio; Jelinek, Christopher J.; Arthasery, Phyllis; Brown, Rodney C.; Murrell, Victor Leon; McMordie, Austin; Sharma, Suman; Chaplin, David J.; Pinney, Kevin G.; Journal of Natural Products; vol. 72; nb. 3; (2009); p. 414 - 421, View in Reaxys; Bao, Kai; Fan, Aixue; Dai, Yi; Zhang, Liang; Zhang, Weige; Cheng, Maosheng; Yao, Xinsheng; Organic and Biomolecular Chemistry; vol. 7; nb. 24; (2009); p. 5084 - 5090, View in Reaxys; Ding, Junwei; Qi, Rongwei; Zhou, Haitang; Jiao, Bin; Xia, Yamu; Journal of Chemical Research; vol. 35; nb. 9; (2011); p. 519 - 521, View in Reaxys

yellow

Luo, Jian-Rong; Jiang, Hong-En; Zhao, You-Xing; Zhou, Jun; Qian, Jin-Fu; Chemistry of Natural Compounds; vol. 44; nb. 1; (2008); p. 6 - 9, View in Reaxys; Tripathi; Sama; Taneja; Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry; vol. 49; nb. 3; (2010); p. 379 - 381, View in Reaxys; Chung, Cheng-Pei; Hsia, ShihMin; Lee, Ming-Yi; Chen, Hong-Jhang; Cheng, Faiwen; Chan, Lu-Chi; Kuo, YuehHsiung; Lin, Yun-Lian; Chiang, Wenchang; Journal of Agricultural and Food Chemistry; vol. 59; nb. 11; (2011); p. 6025 - 6033, View in Reaxys

brown

Lee, Hak-Ju; Khan; Kang, Ha-Young; Choi, Don-Ha; Mi-Jin, Park; Hyun-Jung, Lee; Chemistry of Natural Compounds; vol. 46; nb. 2; (2010); p. 289 - 290, View in Reaxys

light-yellow

Deng; Newman; Hecht; Journal of Natural Products; vol. 63; nb. 9; (2000); p. 1269 1272, View in Reaxys; Wang, Ying; Yang, Min; Yuan, Cheng-Shan; Han, Yi-Feng; Jia, Zhong-Jian; Pharmazie; vol. 58; nb. 8; (2003); p. 596 - 598, View in Reaxys; Duarte, Noelia; Ferreira, Maria-Jose U.; Organic Letters; vol. 9; nb. 3; (2007); p. 489 - 492, View in Reaxys

red - brown

Chen, Chung-Yi; Chang, Fang-Rong; Teng, Che-Ming; Wu, Yang-Chang; Journal of the Chinese Chemical Society; vol. 46; nb. 1; (1999); p. 77 - 86, View in Reaxys

Nadeln

Pauly; Strassberger; Chemische Berichte; vol. 62; (1929); p. 2279, View in Reaxys; Spaeth; Monatshefte fuer Chemie; vol. 41; (1920); p. 278, View in Reaxys; Imaki et al.; Nippon Nogei Kagaku Kaishi; vol. 20; (1944); p. 289,292; Chem.Abstr.; (1949); p. 1743, View in Reaxys; Manske; Ledingham; Holmes; Canadian Journal of Research, Section B: Chemical Sciences; vol. 23; (1945); p. 100,102, View in Reaxys

braeunlich

Koerner; Gazzetta Chimica Italiana; vol. 18; (1888); p. 215, View in Reaxys

Dissociation Exponent (2) 1 of 2

Dissociation Exponent (pK)

7.3

Solvent (Dissociation Exponent)

H2O

Method (Dissociation Exponent)

spectrophotometric

16/130

2017-10-08 12:35:19

Type (Dissociation Exponent)

a1/apparent

Comment (Dissociation Exponent)

ground state

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 2 of 2

Dissociation Exponent (pK)

-6.7 - 7.39

Method (Dissociation Exponent)

spectrophotometric

Type (Dissociation Exponent)

a1/apparent

Comment (Dissociation Exponent)

excited singlet state

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys Further Information (4) Description (Fur- References ther Information) Further information

Kovacik et al.; Chemische Berichte; vol. 102; (1969); p. 1513, View in Reaxys

Further information

Underwood; Filipic; Journal of the Association of Official Agricultural Chemists; vol. 46; (1963); p. 334,336, View in Reaxys

Further information

Bodju; Ljalikow; J. Anal. Chem. USSR (Engl. Transl.); vol. 18; (1963); p. 1007,870, View in Reaxys

Further information

Pearl; Beyer; Journal of Organic Chemistry; vol. 26; (1961); p. 546, View in Reaxys

Solubility (MCS) (1) 1 of 1

Comment (Solubility (MCS))

soluble in magnetized water

Bakherad, Mohammad; Keivanloo, Ali; Gholizadeh, Mostafa; Doosti, Rahele; Javanmardi, Mohaddese; Research on Chemical Intermediates; vol. 43; nb. 2; (2017); p. 1013 - 1029, View in Reaxys NMR Spectroscopy (45) 1 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- d(4)-methanol scopy) Frequency (NMR Spectroscopy) [MHz]

400

Location

supporting information

Mo, Eun Jin; Ahn, Jong Hoon; Jo, Yang Hee; Kim, Seon Beom; Hwang, Bang Yeon; Lee, Mi Kyeong; Molecules; vol. 22; nb. 8; (2017); Art.No: 1349, View in Reaxys 2 of 45

Description (NMR Spec- Chemical shifts; Spectrum troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- dimethylsulfoxide-d6 scopy) Frequency (NMR Spectroscopy) [MHz]

500

Location

supporting information

17/130

2017-10-08 12:35:19

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys; Kärkäs, Markus D.; Bosque, Irene; Matsuura, Bryan S.; Stephenson, Corey R. J.; Organic Letters; vol. 18; nb. 19; (2016); p. 5166 - 5169, View in Reaxys 3 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- d(4)-methanol scopy) Frequency (NMR Spectroscopy) [MHz]

400

Chang, Ruijie; Wang, Chunhui; Zeng, Qi; Guan, Bin; Zhang, Weidong; Jin, Huizi; Archives of Pharmacal Research; vol. 36; nb. 11; (2013); p. 1291 - 1301, View in Reaxys; Chi, Jun; Li, Bao-Cai; Yang, Bo-Tao; Zhang, Mi; Journal of the Chemical Society of Pakistan; vol. 38; nb. 3; (2016); p. 533 - 537, View in Reaxys 4 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- d(4)-methanol scopy) Frequency (NMR Spectroscopy) [MHz]

700

Hong, Seong Su; Choi, Chun Whan; Choi, Yun-Hyeok; Oh, Joa Sub; Phytochemistry Letters; vol. 17; (2016); p. 152 - 157, View in Reaxys 5 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- d(4)-methanol scopy) Frequency (NMR Spectroscopy) [MHz]

175

Hong, Seong Su; Choi, Chun Whan; Choi, Yun-Hyeok; Oh, Joa Sub; Phytochemistry Letters; vol. 17; (2016); p. 152 - 157, View in Reaxys 6 of 45

Description (NMR Spec- Chemical shifts; Spectrum troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- dimethylsulfoxide-d6 scopy) Frequency (NMR Spectroscopy) [MHz]

126

Location

supporting information

Kärkäs, Markus D.; Bosque, Irene; Matsuura, Bryan S.; Stephenson, Corey R. J.; Organic Letters; vol. 18; nb. 19; (2016); p. 5166 - 5169, View in Reaxys 7 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

100

18/130

2017-10-08 12:35:19

Pettit, George R.; Melody, Noeleen; Thornhill, Andrew; Knight, John C.; Groy, Thomas L.; Herald, Cherry L.; Journal of Natural Products; vol. 72; nb. 9; (2009); p. 1637 - 1642, View in Reaxys; Sribuhom, Thurdpong; Sriphana, Uraiwan; Thongsri, Yordhathai; Yenjai, Chavi; Phytochemistry Letters; vol. 11; (2015); p. 80 - 84, View in Reaxys 8 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

400

Bao, Kai; Fan, Aixue; Dai, Yi; Zhang, Liang; Zhang, Weige; Cheng, Maosheng; Yao, Xinsheng; Organic and Biomolecular Chemistry; vol. 7; nb. 24; (2009); p. 5084 - 5090, View in Reaxys; Sribuhom, Thurdpong; Sriphana, Uraiwan; Thongsri, Yordhathai; Yenjai, Chavi; Phytochemistry Letters; vol. 11; (2015); p. 80 - 84, View in Reaxys 9 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

400

Guo, Ying; Ji, Si-Zhe; Chen, Cheng; Liu, Hong-Wei; Zhao, Jian-Hong; Zheng, Yu-Lin; Ji, Ya-Fei; Research on Chemical Intermediates; vol. 41; nb. 11; (2015); p. 8651 - 8664, View in Reaxys 10 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

100

Guo, Ying; Ji, Si-Zhe; Chen, Cheng; Liu, Hong-Wei; Zhao, Jian-Hong; Zheng, Yu-Lin; Ji, Ya-Fei; Research on Chemical Intermediates; vol. 41; nb. 11; (2015); p. 8651 - 8664, View in Reaxys 11 of 45

Description (NMR Spec- Spectrum troscopy) Nucleus (NMR Spectroscopy)

Location

supporting information

Nguyen, Bichlien H.; Perkins, Robert J.; Smith, Jake A.; Moeller, Kevin D.; Journal of Organic Chemistry; vol. 80; nb. 24; (2015); p. 11953 - 11962, View in Reaxys 12 of 45

Description (NMR Spec- HSQC (Heteronuclear Single Quantum Coherence); Spectrum troscopy) Nucleus (NMR Spectroscopy)

13C; 1H

Solvents (NMR Spectro- dimethylsulfoxide-d6 scopy) Mbotchak, Laurie; Le Morvan, Clara; Duong, Khanh Linh; Rousseau, Brigitte; Tessier, Martine; Fradet, Alain; Journal of Agricultural and Food Chemistry; vol. 63; nb. 21; (2015); p. 5178 - 5188, View in Reaxys 13 of 45

Description (NMR Spec- Chemical shifts troscopy)

19/130

2017-10-08 12:35:19

Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

500

Lee, Hak-Ju; Khan; Kang, Ha-Young; Choi, Don-Ha; Mi-Jin, Park; Hyun-Jung, Lee; Chemistry of Natural Compounds; vol. 46; nb. 2; (2010); p. 289 - 290, View in Reaxys; Itoh, Tomohiro; Tsukane, Mariko; Koike, Minako; Nakamura, Chizu; Ohguchi, Kenji; Ito, Masafumi; Akao, Yukihiro; Koshimizu, Seiichi; Nozawa, Yoshinori; Wakimoto, Toshiyuki; Nukaya, Haruo; Suwa, Yoshihide; Journal of Agricultural and Food Chemistry; vol. 58; nb. 12; (2010); p. 7149 - 7157, View in Reaxys; Kang, Ya-Fei; Liu, Chi-Ming; Kao, Chiu-Li; Chen, Chung-Yi; Molecules; vol. 19; nb. 4; (2014); p. 4235 - 4245, View in Reaxys 14 of 45

Description (NMR Spec- Chemical shifts; Spectrum troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

400

Location

supporting information

Description (NMR Spec- Chemical shifts; Spectrum troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

100

Location

supporting information

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

300

Location

supporting information

Li, Lin-Zhen; Wang, Meng-Hua; Sun, Jian-Bo; Liang, Jing-Yu; Natural Product Research; vol. 28; nb. 15; (2014); p. 1214 - 1217, View in Reaxys 17 of 45

Description (NMR Spec- Chemical shifts troscopy)

20/130

2017-10-08 12:35:19

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

Location

supporting information

Li, Lin-Zhen; Wang, Meng-Hua; Sun, Jian-Bo; Liang, Jing-Yu; Natural Product Research; vol. 28; nb. 15; (2014); p. 1214 - 1217, View in Reaxys 18 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- d(4)-methanol scopy) Frequency (NMR Spectroscopy) [MHz]

100

Chang, Ruijie; Wang, Chunhui; Zeng, Qi; Guan, Bin; Zhang, Weidong; Jin, Huizi; Archives of Pharmacal Research; vol. 36; nb. 11; (2013); p. 1291 - 1301, View in Reaxys 19 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

200

Ding, Junwei; Qi, Rongwei; Zhou, Haitang; Jiao, Bin; Xia, Yamu; Journal of Chemical Research; vol. 35; nb. 9; (2011); p. 519 - 521, View in Reaxys 20 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- [(2)H6]acetone scopy) Frequency (NMR Spectroscopy) [MHz]

400

Chung, Cheng-Pei; Hsia, Shih-Min; Lee, Ming-Yi; Chen, Hong-Jhang; Cheng, Faiwen; Chan, Lu-Chi; Kuo, Yueh-Hsiung; Lin, Yun-Lian; Chiang, Wenchang; Journal of Agricultural and Food Chemistry; vol. 59; nb. 11; (2011); p. 6025 - 6033, View in Reaxys 21 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Tripathi; Sama; Taneja; Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry; vol. 49; nb. 3; (2010); p. 379 - 381, View in Reaxys 22 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

21/130

2017-10-08 12:35:19

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

400

Location

supporting information

Ferreira, Fernanda Peres; De Oliveira, Dioneia Camilo Rodrigues; Tetrahedron Letters; vol. 51; nb. 52; (2010); p. 6856 - 6859, View in Reaxys 23 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

125

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Frequency (NMR Spectroscopy) [MHz]

300

Shirali, Anupama; Sriram, Madhavi; Hall, John J.; Nguyen, Benson L.; Guddneppanavar, Rajsekhar; Hadimani, Mallinath B.; Ackley, J. Freeland; Siles, Rogelio; Jelinek, Christopher J.; Arthasery, Phyllis; Brown, Rodney C.; Murrell, Victor Leon; McMordie, Austin; Sharma, Suman; Chaplin, David J.; Pinney, Kevin G.; Journal of Natural Products; vol. 72; nb. 3; (2009); p. 414 - 421, View in Reaxys; Pettit, George R.; Melody, Noeleen; Thornhill, Andrew; Knight, John C.; Groy, Thomas L.; Herald, Cherry L.; Journal of Natural Products; vol. 72; nb. 9; (2009); p. 1637 - 1642, View in Reaxys 26 of 45

Description (NMR Spec- Chemical shifts; Spectrum troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- chloroform-d1 scopy) Location

supporting information

Bao, Kai; Fan, Aixue; Dai, Yi; Zhang, Liang; Zhang, Weige; Cheng, Maosheng; Yao, Xinsheng; Organic and Biomolecular Chemistry; vol. 7; nb. 24; (2009); p. 5084 - 5090, View in Reaxys

22/130

2017-10-08 12:35:19

27 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- CDCl3 scopy) Frequency (NMR Spectroscopy) [MHz]

125

Luo, Jian-Rong; Jiang, Hong-En; Zhao, You-Xing; Zhou, Jun; Qian, Jin-Fu; Chemistry of Natural Compounds; vol. 44; nb. 1; (2008); p. 6 - 9, View in Reaxys 28 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- CDCl3 scopy) Frequency (NMR Spectroscopy) [MHz]

400

Takaki, Ken; Shimasaki, Yohei; Shishido, Tetsuya; Takehira, Katsuomi; Bulletin of the Chemical Society of Japan; vol. 75; nb. 2; (2002); p. 311 - 317, View in Reaxys; Duarte, Noelia; Ferreira, Maria-Jose U.; Organic Letters; vol. 9; nb. 3; (2007); p. 489 - 492, View in Reaxys 29 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- CDCl3 scopy) Manchand, Percy S.; Belica, Peter S.; Wong, Harry S.; Synthetic Communications; vol. 20; nb. 17; (1990); p. 2659 - 2666, View in Reaxys; Rao, Durvasula V.; Stuber, F. A.; Synthesis; nb. 4; (1983); p. 308, View in Reaxys; Rizzacasa, Mark A.; Sargent, Melvyn V.; Australian Journal of Chemistry; vol. 40; nb. 10; (1987); p. 1737 - 1743, View in Reaxys; Puri, S. C.; Anand, S. M.; Atal, C. K.; Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry; vol. 24; (1985); p. 294 - 295, View in Reaxys; Borges-Del-Castillo, Juan; BradleyDelso, Antonio; Manresa-Ferrero, Ma. Teresa; Vazquez-Bueno, Purificacion; Rodriguez-Luis, Francisco; Phytochemistry (Elsevier); vol. 22; nb. 3; (1983); p. 782 - 783, View in Reaxys; Gutierrez, Alicia B.; Herz, Werner; Phytochemistry (Elsevier); vol. 27; nb. 12; (1988); p. 3871 - 3874, View in Reaxys; Chiji, Hideyuki; Tanaka, Shigenori; Izawa, Masao; Agricultural and Biological Chemistry; vol. 44; nb. 1; (1980); p. 205 - 208, View in Reaxys; Gaillard; Muyard; Bevalot; Regnier; Vaquette; Annales pharmaceutiques francaises; vol. 53; nb. 2; (1995); p. 75 - 78, View in Reaxys; Chen, Chung-Yi; Chang, Fang-Rong; Teng, Che-Ming; Wu, Yang-Chang; Journal of the Chinese Chemical Society; vol. 46; nb. 1; (1999); p. 77 - 86, View in Reaxys; Lee, Tzong-Huei; Chiou, Jong-Liang; Lee, Ching-Kuo; Kuo, Yueh-Hsiung; Journal of the Chinese Chemical Society; vol. 52; nb. 4; (2005); p. 833 - 841, View in Reaxys 30 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- CDCl3 scopy) Frequency (NMR Spectroscopy) [MHz]

Ren, Xinfeng; Chen, Xiaochuan; Peng, Kun; Xie, Xingang; Xia, Yamu; Pan, Xinfu; Tetrahedron Asymmetry; vol. 13; nb. 16; (2002); p. 1799 - 1804, View in Reaxys; Su, Ying; Ren, Xin-Feng; She, Xue-Gong; Pan, Xin-Fu; Journal of the Chinese Chemical Society; vol. 51; nb. 6; (2004); p. 1333 - 1337, View in Reaxys 31 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

23/130

2017-10-08 12:35:19

Solvents (NMR Spectro- CDCl3 scopy) Frequency (NMR Spectroscopy) [MHz]

200

Wang, Ying; Yang, Min; Yuan, Cheng-Shan; Han, Yi-Feng; Jia, Zhong-Jian; Pharmazie; vol. 58; nb. 8; (2003); p. 596 - 598, View in Reaxys 32 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- acetone-d6 scopy) Kim, Hoon; Ralph, John; Lu, Fachuang; Ralph, Sally A.; Boudet, Alain-M.; MacKay, John J.; Sederoff, Ronald R.; Ito, Takashi; Kawai, Shingo; Ohashi, Hideo; Higuchi, Takayoshi; Organic and Biomolecular Chemistry; vol. 1; nb. 2; (2003); p. 268 - 281, View in Reaxys 33 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- CDCl3 scopy) Frequency (NMR Spectroscopy) [MHz]

Takaki, Ken; Shimasaki, Yohei; Shishido, Tetsuya; Takehira, Katsuomi; Bulletin of the Chemical Society of Japan; vol. 75; nb. 2; (2002); p. 311 - 317, View in Reaxys 35 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- CDCl3 scopy) Frequency (NMR Spectroscopy) [MHz]

Lee, Ching-Kuo; Chang, Ming-Huey; Journal of the Chinese Chemical Society; vol. 47; nb. 3; (2000); p. 555 - 560, View in Reaxys 36 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- CDCl3 scopy) Frequency (NMR Spectroscopy) [MHz]

300

24/130

2017-10-08 12:35:19

Baik, Woonphil; Lee, Hyun Joo; Jang, Jung Min; Koo, Sangho; Kim, Byeong Hyo; Journal of Organic Chemistry; vol. 65; nb. 1; (2000); p. 108 - 115, View in Reaxys; Lee, Ching-Kuo; Chang, Ming-Huey; Journal of the Chinese Chemical Society; vol. 47; nb. 3; (2000); p. 555 - 560, View in Reaxys 37 of 45

Description (NMR Spec- 2D-NMR troscopy) Nucleus (NMR Spectroscopy)

1H; 13C

Kim, Hoon; Ralph, John; Yahiaoui, Nabila; Pean, Michel; Boudet, Alain-M.; Organic Letters; vol. 2; nb. 15; (2000); p. 2197 - 2200, View in Reaxys 38 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Solvents (NMR Spectro- acetone-d6 scopy) Frequency (NMR Spectroscopy) [MHz]

200

Cai; Arntfield; Charlton; JAOCS, Journal of the American Oil Chemists' Society; vol. 76; nb. 4; (1999); p. 433 441, View in Reaxys 39 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- acetone-d6 scopy) Frequency (NMR Spectroscopy) [MHz]

Cai; Arntfield; Charlton; JAOCS, Journal of the American Oil Chemists' Society; vol. 76; nb. 4; (1999); p. 433 441, View in Reaxys 40 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

Claus,P. et al.; Monatshefte fuer Chemie; vol. 103; (1972); p. 1178 - 1193, View in Reaxys; Kokpol, Udom; Chavasiri, Warinthorn; Chittawong, Vallapa; Bruce, Marc; Cunningham, G. N.; et al.; Phytochemistry (Elsevier); vol. 33; nb. 5; (1993); p. 1129 - 1132, View in Reaxys 41 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Kokpol, Udom; Chavasiri, Warinthorn; Chittawong, Vallapa; Bruce, Marc; Cunningham, G. N.; et al.; Phytochemistry (Elsevier); vol. 33; nb. 5; (1993); p. 1129 - 1132, View in Reaxys 42 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- CDCl3 scopy) Temperature (NMR Spectroscopy) [°C]

Malterud, Karl Egil; Anthonsen, Thorleif; Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry; vol. 41; nb. 1; (1987); p. 6 - 12, View in Reaxys

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43 of 45

Description (NMR Spec- Spin-lattice relaxation time (T1) troscopy) Malterud, Karl Egil; Anthonsen, Thorleif; Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry; vol. 41; nb. 1; (1987); p. 6 - 12, View in Reaxys

44 of 45

Description (NMR Spec- Chemical shifts troscopy) Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectro- dimethylsulfoxide-d6 scopy) Fujita; Yamada; Nakajima; Kawai; Nagai; Chemical and pharmaceutical bulletin; vol. 32; nb. 7; (1984); p. 2622 2627, View in Reaxys 45 of 45

Description (NMR Spec- NMR troscopy) Luedemann,H.; Nimz,H.; Makromolekulare Chemie; vol. 175; (1974); p. 2393, View in Reaxys; Yokota et al.; Yakugaku Zasshi; vol. 98; (1978); p. 1607,1608; Chem.Abstr.; vol. 90; nb. 135083h; (1979), View in Reaxys; Lehrer; Stevenson; Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999); (1974); p. 1165, View in Reaxys

IR Spectroscopy (15) 1 of 15

Description (IR Spectroscopy)

Bands; Spectrum

Solvent (IR Spectroscopy)

dimethylsulfoxide-d6

Yancheva; Velcheva; Glavcheva; Stamboliyska; Smelcerovic; Journal of Molecular Structure; vol. 1108; (2016); p. 552 - 559, View in Reaxys 2 of 15

Description (IR Spectroscopy)

Bands

Hergert,H.L.; Journal of Organic Chemistry; vol. 25; (1960); p. 405 - 413, View in Reaxys; Michell; Australian Journal of Chemistry; vol. 19; (1966); p. 2285,2288, View in Reaxys; Santavy et al.; Acta Universitatis Palackianae Olomucensis, Facultatis Medicae, Supplementum; vol. 13; (1973); p. 87; Chem.Abstr.; vol. 81; nb. 25219, View in Reaxys; Lee, Ching-Kuo; Chang, Ming-Huey; Journal of the Chinese Chemical Society; vol. 47; nb. 3; (2000); p. 555 - 560, View in Reaxys; Lee, Tzong-Huei; Chiou, Jong-Liang; Lee, Ching-Kuo; Kuo, Yueh-Hsiung; Journal of the Chinese Chemical Society; vol. 52; nb. 4; (2005); p. 833 - 841, View in Reaxys; Kang, Ya-Fei; Liu, Chi-Ming; Kao, Chiu-Li; Chen, Chung-Yi; Molecules; vol. 19; nb. 4; (2014); p. 4235 - 4245, View in Reaxys 3 of 15

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

potassium bromide

Description (IR Spectroscopy)

Bands

Comment (IR Spectroscopy)

neat (no solvent, solid phase)

Pettit, George R.; Melody, Noeleen; Thornhill, Andrew; Knight, John C.; Groy, Thomas L.; Herald, Cherry L.; Journal of Natural Products; vol. 72; nb. 9; (2009); p. 1637 - 1642, View in Reaxys 5 of 15

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

KBr

Chen, Chung-Yi; Chang, Fang-Rong; Teng, Che-Ming; Wu, Yang-Chang; Journal of the Chinese Chemical Society; vol. 46; nb. 1; (1999); p. 77 - 86, View in Reaxys; Duarte, Noelia; Ferreira, Maria-Jose U.; Organic Letters; vol. 9; nb. 3; (2007); p. 489 - 492, View in Reaxys

26/130

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6 of 15

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

nujol

Takaki, Ken; Shimasaki, Yohei; Shishido, Tetsuya; Takehira, Katsuomi; Bulletin of the Chemical Society of Japan; vol. 75; nb. 2; (2002); p. 311 - 317, View in Reaxys 7 of 15

Description (IR Spectroscopy)

Bands

Comment (IR Spectroscopy)

3290 - 905 cm**(-1)

Kokpol, Udom; Chavasiri, Warinthorn; Chittawong, Vallapa; Bruce, Marc; Cunningham, G. N.; et al.; Phytochemistry (Elsevier); vol. 33; nb. 5; (1993); p. 1129 - 1132, View in Reaxys 8 of 15

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

CHCl3

Comment (IR Spectroscopy)

3520 - 1685 cm**(-1)

Manchand, Percy S.; Belica, Peter S.; Wong, Harry S.; Synthetic Communications; vol. 20; nb. 17; (1990); p. 2659 - 2666, View in Reaxys 9 of 15

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

KBr

Comment (IR Spectroscopy)

3202 - 1050 cm**(-1)

Gutierrez, Alicia B.; Herz, Werner; Phytochemistry (Elsevier); vol. 27; nb. 12; (1988); p. 3871 - 3874, View in Reaxys 10 of 15

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

KBr

Comment (IR Spectroscopy)

3250 - 1665 cm**(-1)

Puri, S. C.; Anand, S. M.; Atal, C. K.; Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry; vol. 24; (1985); p. 294 - 295, View in Reaxys 11 of 15

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

nujol

Comment (IR Spectroscopy)

3100 - 1685 cm**(-1)

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

KBr

Comment (IR Spectroscopy)

3280 - 1675 cm**(-1)

Chiji, Hideyuki; Tanaka, Shigenori; Izawa, Masao; Agricultural and Biological Chemistry; vol. 44; nb. 1; (1980); p. 205 - 208, View in Reaxys

27/130

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13 of 15

Description (IR Spectroscopy)

Intensity of IR bands

Gol'man; Reznikov; Journal of Applied Spectroscopy; vol. 19; nb. 6; (1973); p. 1664 - 1665, View in Reaxys 14 of 15

Description (IR Spectroscopy)

Bullock; Jones; Journal of the Chemical Society [Section] A: Inorganic, Physical, Theoretical; (1970); p. 2472, View in Reaxys; Skurikhin; Chemistry of Natural Compounds; vol. 3; (1967); p. 172; Khimiya Prirodnykh Soedinenii; vol. 3; (1967); p. 208, View in Reaxys 15 of 15

Description (IR Spectroscopy)

Spectrum

Underwood; Filipic; Journal of the Association of Official Agricultural Chemists; vol. 46; (1963); p. 334,336, View in Reaxys Mass Spectrometry (43) Description (Mass Location Spectrometry)

References

gas chromatography mass spectrometry (GCMS); electron impact (EI); spectrum

Miuc, Alen; Vončina, Ernest; Lešnik, Uroš; Acta Chimica Slovenica; vol. 62; nb. 4; (2015); p. 834 - 848, View in Reaxys; Pagnotta, Eleonora; Agerbirk, Niels; Olsen, Carl E.; Ugolini, Luisa; Cinti, Susanna; Lazzeri, Luca; Journal of Agricultural and Food Chemistry; vol. 65; nb. 15; (2017); p. 3167 - 3178, View in Reaxys

electrospray ionisation (ESI); spectrum

Zhu, Jia-Xian; Qin, Jiang-Jiang; Zhang, Fei; Chang, Rui-Jie; Ren, Jie; Cheng, Xiang-Rong; Zeng, Qi; Jin, Hui-Zi; Zhang, Wei-Dong; Chemistry of Natural Compounds; vol. 49; nb. 2; (2013); p. 383 - 387; Khim. Prir. Soedin.; vol. 49; nb. 2; (2013); p. 324 - 327,4, View in Reaxys; Chang, Ruijie; Wang, Chunhui; Zeng, Qi; Guan, Bin; Zhang, Weidong; Jin, Huizi; Archives of Pharmacal Research; vol. 36; nb. 11; (2013); p. 1291 - 1301, View in Reaxys; Kang, Ya-Fei; Liu, Chi-Ming; Kao, Chiu-Li; Chen, Chung-Yi; Molecules; vol. 19; nb. 4; (2014); p. 4235 - 4245, View in Reaxys; Wang, Chun-Hui; Wei, Pan-Lei; Guan, Bin; Jin, Hui-Zi; Zhang, Wei-Dong; Chemistry of Natural Compounds; vol. 50; nb. 1; (2014); p. 142 - 143; Khim. Prir. Soedin.; nb. 1; (2014); p. 126 - 127,2, View in Reaxys; Hong, Seong Su; Choi, Chun Whan; Choi, Yun-Hyeok; Oh, Joa Sub; Phytochemistry Letters; vol. 17; (2016); p. 152 - 157, View in Reaxys

gas chromatography mass spectrometry (GCMS); spectrum

Palomero, Felipe; Bertani, Paolo; Fernández De Simón, Brígida; Cadahía, Estrella; Benito, Santiago; Morata, Antonio; Suárez-Lepe, José A.; Food Chemistry; vol. 171; (2014); p. 212 - 223, View in Reaxys; Ohra-Aho, Taina; Niemi, Piritta; Aura, Anna-Marja; Orlandi, Marco; Poutanen, Kaisa; Buchert, Johanna; Tamminen, Tarja; Journal of Agricultural and Food Chemistry; vol. 64; nb. 4; (2016); p. 812 - 820, View in Reaxys

gas chromatography mass spectrometry (GCMS); fragmentation pattern; spectrum

Nair, Vaishakh; Dhar, Piyali; Vinu; RSC Advances; vol. 6; nb. 22; (2016); p. 18204 18216, View in Reaxys

electrospray ionisation (ESI); high resolution mass spectrometry (HRMS); spectrum

Barnaba; Dellacassa; Nicolini; Nardin; Malacarne; Larcher; Food Chemistry; vol. 206; (2016); p. 260 - 266, View in Reaxys

liquid chromatography mass spectrometry (LCMS); time-of-flight mass spectra (TOFMS); electrospray ionisation (ESI); tandem mass spectrometry; spectrum

Liu, Meng-Hua; Zhang, Qi; Zhang, Yuan-He; Lu, Xian-Yuan; Fu, Wei-Ming; He, JingYu; Molecules; vol. 21; nb. 9; (2016); Art.No: 1204, View in Reaxys

high resolution mass spectrometry (HRMS); electrospray ionisa-

supporting information

Kärkäs, Markus D.; Bosque, Irene; Matsuura, Bryan S.; Stephenson, Corey R. J.; Organic Letters; vol. 18; nb. 19; (2016); p. 5166 - 5169, View in Reaxys

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2017-10-08 12:35:19

tion (ESI); spectrum tandem mass spectrometry; CID (collision-induced dissociation); IT (ion trap); fragmentation pattern; spectrum

Marcum, Christopher L.; Jarrell, Tiffany M.; Zhu, Hanyu; Owen, Benjamin C.; Haupert, Laura J.; Easton, Mckay; Hosseinaei, Omid; Bozell, Joseph; Nash, John J.; Kenttämaa, Hilkka I.; ChemSusChem; vol. 9; nb. 24; (2016); p. 3513 - 3526, View in Reaxys

MALDI (Matrix assisted laser desorption ionization); time-of-flight mass spectra (TOFMS); spectrum

Ferhan; Yan; Sain; RSC Advances; vol. 5; nb. 20; (2015); p. 14937 - 14952, View in Reaxys

electrospray ionisation (ESI); liquid chromatography mass spectrometry (LCMS); tandem mass spectrometry; spectrum

Chen, Shao-Dan; Lu, Chuan-Jian; Zhao, Rui-Zhi; Molecules; vol. 20; nb. 1; (2015); p. 1594 - 1609, View in Reaxys

liquid chromatography mass spectrometry (LCMS); spectrum

Chen, Shao-Dan; Lu, Chuan-Jian; Zhao, Rui-Zhi; Molecules; vol. 20; nb. 1; (2015); p. 1594 - 1609, View in Reaxys

electron impact (EI); IT (ion trap); spectrum

Tamburini, Diego; Łucejko, Jeannette Jacqueline; Ribechini, Erika; Colombini, Maria Perla; Journal of Mass Spectrometry; vol. 50; nb. 10; (2015); p. 1103 - 1113, View in Reaxys

high resolution mass spectrometry (HRMS); electrospray ionisation (ESI); spectrum

Guo, Ying; Ji, Si-Zhe; Chen, Cheng; Liu, Hong-Wei; Zhao, Jian-Hong; Zheng, YuLin; Ji, Ya-Fei; Research on Chemical Intermediates; vol. 41; nb. 11; (2015); p. 8651 8664, View in Reaxys

electron impact (EI); spectrum

Wang, Huan-Qin; Peng, Chao-Zhong; Chen, Ye-Gao; Chemistry of Natural Compounds; vol. 51; nb. 6; (2015); p. 1167 - 1168; Khim. Prir. Soedin.; vol. 6; (2015); p. 1004 - 1005,2, View in Reaxys

high resolution supporting informass spectrome- mation try (HRMS); electrospray ionisation (ESI); timeof-flight mass spectra (TOFMS); spectrum

Jiang, Jian-An; Du, Jia-Lei; Liao, Dao-Hua; Wang, Zhan-Guo; Ji, Ya-Fei; Tetrahedron Letters; vol. 55; nb. 8; (2014); p. 1406 - 1411, View in Reaxys; Jiang, Jian-An; Du, JiaLei; Wang, Zhan-Guo; Zhang, Zhong-Nan; Xu, Xi; Zheng, Gan-Lin; Ji, Ya-Fei; Tetrahedron Letters; vol. 55; nb. 10; (2014); p. 1677 - 1681, View in Reaxys

electrospray ionisation (ESI); high resolution mass spectrometry (HRMS); time-offlight mass spectra (TOFMS); spectrum

Jiang, Jian-An; Chen, Cheng; Huang, Jian-Gang; Liu, Hong-Wei; Cao, Song; Ji, YaFei; Green Chemistry; vol. 16; nb. 3; (2014); p. 1248 - 1254, View in Reaxys

supporting information

electrospray ionisation (ESI); fragmentation pattern; spectrum electrospray ionisation (ESI); liquid chromatogra-

Jarrell, Tiffany M.; Marcum, Christopher L.; Sheng, Huaming; Owen, Benjamin C.; O'Lenick; Maraun, Hagen; Bozell, Joseph J.; Kenttaemaa, Hilkka I.; Green Chemistry; vol. 16; nb. 5; (2014); p. 2713 - 2727, View in Reaxys supporting information

Li, Lin-Zhen; Wang, Meng-Hua; Sun, Jian-Bo; Liang, Jing-Yu; Natural Product Research; vol. 28; nb. 15; (2014); p. 1214 - 1217, View in Reaxys

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2017-10-08 12:35:19

phy mass spectrometry (LCMS); spectrum tandem mass spectrometry; electrospray ionisation (ESI); spectrum

TeA eviAe , Vele; AljanAe iAe , Ivana; Vajs, Vlatka; A ivkoviAe , Marijana; NikiAe eviAe , Ninoslav; UroA eviAe , Ivan; VujisiAe , Ljubodrag; Journal of the Serbian Chemical Society; vol. 79; nb. 12; (2014); p. 1537 - 1543, View in Reaxys

high resolution supporting informass spectrome- mation try (HRMS); electrospray ionisation (ESI); liquid chromatography mass spectrometry (LCMS); timeof-flight mass spectra (TOFMS); spectrum

Jiang, Jian-An; Du, Jia-Lei; Zhang, Zhong-Nan; Zhai, Jiao-Jiao; Ji, Ya-Fei; Synthetic Communications; vol. 44; nb. 10; (2014); p. 1430 - 1440, View in Reaxys

time-of-flight mass spectra (TOFMS); spectrum

Dufour, Anthony; Weng, Junjie; Jia, Liangyuan; Tang, Xiaofeng; Sirjean, Baptiste; Fournet, Rene; Gall, Herve Le; Brosse, Nicolas; Billaud, Francis; Mauviel, Guillain; Qi, Fei; RSC Advances; vol. 3; nb. 14; (2013); p. 4786 - 4792, View in Reaxys

ESI (Electrospray ionisation)

Page/Page column 47

GCMS (Gas chromatography mass spectrometry); EI (Electron impact); Spectrum

Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.; Food Chemistry; vol. 133; nb. 3; (2012); p. 697 - 706, View in Reaxys

ESI (Electrospray ionisation); Tandem mass spectrometry; Negative ion spectroscopy; Spectrum

Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.; Food Chemistry; vol. 133; nb. 3; (2012); p. 697 - 706, View in Reaxys

LCMS (Liquid chromatography mass spectrometry); ESI (Electrospray ionisation); Tandem mass spectrometry; Negative ion spectroscopy; Spectrum

Sanz, Miriam; De Simon, Brigida Fernandez; Cadahia, Estrella; Esteruelas, Enrique; Munoz, Angel M.; Hernandez, Teresa; Estrella, Isabel; Pinto, Ernani; Journal of Mass Spectrometry; vol. 47; nb. 7; (2012); p. 905 - 918, View in Reaxys

electrospray ionisation (ESI); spectrum

supporting information

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys

liquid chromatography mass spectrometry (LCMS); electrospray ionisation (ESI); IT (ion trap); fragmentation pattern; spectrum

Spectrum

Sanz, Miriam; Cadahia, Estrella; Esteruelas, Enrique; Munoz, Angel Ma; Fernandez De Simon, Brigida; Hernandez, Teresa; Estrella, Isabel; Journal of Agricultural and Food Chemistry; vol. 58; nb. 8; (2010); p. 4907 - 4914, View in Reaxys; Sanz, Miriam; Fernandez De Simon, Brigida; Esteruelas, Enrique; Munoz, Angel M; Cadahia, Estrella; Hernandez, Teresa; Estrella, Isabel; Pinto, Ernani; Journal of Agricultural and Food Chemistry; vol. 59; nb. 7; (2011); p. 3135 - 3145, View in Reaxys

30/130

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Tandem mass spectrometry; ESI (Electrospray ionisation); Spectrum

Sanz, Miriam; Fernandez De Simon, Brigida; Esteruelas, Enrique; Munoz, Angel M; Cadahia, Estrella; Hernandez, Teresa; Estrella, Isabel; Pinto, Ernani; Journal of Agricultural and Food Chemistry; vol. 59; nb. 7; (2011); p. 3135 - 3145, View in Reaxys

EI (Electron impact); Spectrum

Nakabayashi, Ryo; Kusano, Miyako; Kobayashi, Makoto; Tohge, Takayuki; Yonekura-Sakakibara, Keiko; Kogure, Noriyuki; Yamazaki, Mami; Kitajima, Mariko; Saito, Kazuki; Takayama, Hiromitsu; Phytochemistry; vol. 70; nb. 8; (2009); p. 1017 - 1029, View in Reaxys; Lee, Hak-Ju; Khan; Kang, Ha-Young; Choi, Don-Ha; Mi-Jin, Park; Hyun-Jung, Lee; Chemistry of Natural Compounds; vol. 46; nb. 2; (2010); p. 289 - 290, View in Reaxys; Ding, Junwei; Qi, Rongwei; Zhou, Haitang; Jiao, Bin; Xia, Yamu; Journal of Chemical Research; vol. 35; nb. 9; (2011); p. 519 - 521, View in Reaxys; Chung, Cheng-Pei; Hsia, Shih-Min; Lee, Ming-Yi; Chen, Hong-Jhang; Cheng, Faiwen; Chan, Lu-Chi; Kuo, Yueh-Hsiung; Lin, Yun-Lian; Chiang, Wenchang; Journal of Agricultural and Food Chemistry; vol. 59; nb. 11; (2011); p. 6025 - 6033, View in Reaxys

ESI (Electrospray ionisation); Negative ion spectroscopy; LCMS (Liquid chromatography mass spectrometry); Spectrum

supporting information

Ferreira, Fernanda Peres; De Oliveira, Dioneia Camilo Rodrigues; Tetrahedron Letters; vol. 51; nb. 52; (2010); p. 6856 - 6859, View in Reaxys

TOFMS (Time of flight mass spectrum); GCMS (Gas chromatography mass spectrometry); EI (Electron impact); Spectrum

Faustino, Helio; Gil, Nuno; Baptista, Cecilia; Duarte, Ana Paula; Molecules; vol. 15; nb. 12; (2010); p. 9308 - 9322, View in Reaxys

FAB (Fast atom bombardment); Spectrum

Itoh, Tomohiro; Tsukane, Mariko; Koike, Minako; Nakamura, Chizu; Ohguchi, Kenji; Ito, Masafumi; Akao, Yukihiro; Koshimizu, Seiichi; Nozawa, Yoshinori; Wakimoto, Toshiyuki; Nukaya, Haruo; Suwa, Yoshihide; Journal of Agricultural and Food Chemistry; vol. 58; nb. 12; (2010); p. 7149 - 7157, View in Reaxys

GCMS (Gas chromatography mass spectrometry); Spectrum

Marques, Gisela; Gutierrez, Ana; Del Rio, Jose C.; Journal of Agricultural and Food Chemistry; vol. 55; nb. 4; (2007); p. 1327 - 1336, View in Reaxys; Stärk, Kerstin; Taccardi, Nicola; Bösmann, Andreas; Wasserscheid, Peter; ChemSusChem; vol. 3; nb. 6; (2010); p. 719 - 723, View in Reaxys

HRMS (High resolution mass spectrometry); EI (Electron impact); Spectrum

Shirali, Anupama; Sriram, Madhavi; Hall, John J.; Nguyen, Benson L.; Guddneppanavar, Rajsekhar; Hadimani, Mallinath B.; Ackley, J. Freeland; Siles, Rogelio; Jelinek, Christopher J.; Arthasery, Phyllis; Brown, Rodney C.; Murrell, Victor Leon; McMordie, Austin; Sharma, Suman; Chaplin, David J.; Pinney, Kevin G.; Journal of Natural Products; vol. 72; nb. 3; (2009); p. 414 - 421, View in Reaxys; Pettit, George R.; Melody, Noeleen; Thornhill, Andrew; Knight, John C.; Groy, Thomas L.; Herald, Cherry L.; Journal of Natural Products; vol. 72; nb. 9; (2009); p. 1637 - 1642, View in Reaxys

LCMS (Liquid chromatography mass spectrometry); ESI (Electrospray ionisation); Spectrum

Mohn, Tobias; Plitzko, Inken; Hamburger, Matthias; Phytochemistry; vol. 70; nb. 7; (2009); p. 924 - 934, View in Reaxys

Tandem mass spectrometry; Spectrum

Mohn, Tobias; Plitzko, Inken; Hamburger, Matthias; Phytochemistry; vol. 70; nb. 7; (2009); p. 924 - 934, View in Reaxys

APCI (atmospheric pressure chemical ionization); Spectrum

Mohn, Tobias; Plitzko, Inken; Hamburger, Matthias; Phytochemistry; vol. 70; nb. 7; (2009); p. 924 - 934, View in Reaxys

ESI (Electrospray ionisation); Spectrum

Bao, Kai; Fan, Aixue; Dai, Yi; Zhang, Liang; Zhang, Weige; Cheng, Maosheng; Yao, Xinsheng; Organic and Biomolecular Chemistry; vol. 7; nb. 24; (2009); p. 5084 - 5090, View in Reaxys

31/130

2017-10-08 12:35:19

spectrum; electron impact (EI)

Chen, Chung-Yi; Chang, Fang-Rong; Teng, Che-Ming; Wu, Yang-Chang; Journal of the Chinese Chemical Society; vol. 46; nb. 1; (1999); p. 77 - 86, View in Reaxys; Lee, Ching-Kuo; Chang, Ming-Huey; Journal of the Chinese Chemical Society; vol. 47; nb. 3; (2000); p. 555 - 560, View in Reaxys; Soares de Moura; Costa; Jansen; Silva; Lopes; Bernardo-Filho; Nascimento da Silva; Criddle; Portela, B Nunes; Rubenich; Araujo, R Gagliardi; Carvalho; The Journal of pharmacy and pharmacology; vol. 54; nb. 2; (2002); p. 249 - 256, View in Reaxys; Wang, Ying; Yang, Min; Yuan, ChengShan; Han, Yi-Feng; Jia, Zhong-Jian; Pharmazie; vol. 58; nb. 8; (2003); p. 596 - 598, View in Reaxys; Duarte, Noelia; Ferreira, Maria-Jose U.; Organic Letters; vol. 9; nb. 3; (2007); p. 489 - 492, View in Reaxys; Luo, Jian-Rong; Jiang, Hong-En; Zhao, YouXing; Zhou, Jun; Qian, Jin-Fu; Chemistry of Natural Compounds; vol. 44; nb. 1; (2008); p. 6 - 9, View in Reaxys

spectrum; fast atom bombardment (FAB)

Lee, Tzong-Huei; Chiou, Jong-Liang; Lee, Ching-Kuo; Kuo, Yueh-Hsiung; Journal of the Chinese Chemical Society; vol. 52; nb. 4; (2005); p. 833 - 841, View in Reaxys

spectrum

Manchand, Percy S.; Belica, Peter S.; Wong, Harry S.; Synthetic Communications; vol. 20; nb. 17; (1990); p. 2659 - 2666, View in Reaxys; Borges-Del-Castillo, Juan; Bradley-Delso, Antonio; Manresa-Ferrero, Ma. Teresa; Vazquez-Bueno, Purificacion; Rodriguez-Luis, Francisco; Phytochemistry (Elsevier); vol. 22; nb. 3; (1983); p. 782 - 783, View in Reaxys; Hartley, Roy D.; Keene, Annie S.; Phytochemistry (Elsevier); vol. 23; nb. 6; (1984); p. 1305 - 1308, View in Reaxys; Cai; Arntfield; Charlton; JAOCS, Journal of the American Oil Chemists' Society; vol. 76; nb. 4; (1999); p. 433 - 441, View in Reaxys; Tan, Jianwen; Bednarek, Pawel; Liu, Jikai; Schneider, Bernd; Svatos, Ales; Hahlbrock, Klaus; Phytochemistry; vol. 65; nb. 6; (2004); p. 691 - 699, View in Reaxys Ciaramitaro,D.; Steelink,C.; Phytochemistry (Elsevier); vol. 14; (1975); p. 543 - 552, View in Reaxys; Kovacik et al.; Chemische Berichte; vol. 102; (1969); p. 1513, View in Reaxys

UV/VIS Spectroscopy (58) 1 of 58

Solvent (UV/VIS Spectroscopy)

acetonitrile

Absorption Maxima (UV/ 216; 230; 308 VIS) [nm] Kang, Ya-Fei; Liu, Chi-Ming; Kao, Chiu-Li; Chen, Chung-Yi; Molecules; vol. 19; nb. 4; (2014); p. 4235 - 4245, View in Reaxys 2 of 58

Solvent (UV/VIS Spectroscopy)

water

Absorption Maxima (UV/ 300; 217 VIS) [nm] Jenita, M. Jude; Mohandass; Rajendiran; Journal of Fluorescence; vol. 24; nb. 3; (2014); p. 695 - 707, View in Reaxys 3 of 58

Solvent (UV/VIS Spectroscopy)

cyclohexane

Absorption Maxima (UV/ 300; 288; 226; 217 VIS) [nm] Jenita, M. Jude; Mohandass; Rajendiran; Journal of Fluorescence; vol. 24; nb. 3; (2014); p. 695 - 707, View in Reaxys 4 of 58

Solvent (UV/VIS Spectroscopy)

methanol

Absorption Maxima (UV/ 308; 254; 215 VIS) [nm] Jenita, M. Jude; Mohandass; Rajendiran; Journal of Fluorescence; vol. 24; nb. 3; (2014); p. 695 - 707, View in Reaxys 5 of 58

Solvent (UV/VIS Spectroscopy)

1,4-dioxane

Absorption Maxima (UV/ 309; 230 VIS) [nm]

32/130

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Jenita, M. Jude; Mohandass; Rajendiran; Journal of Fluorescence; vol. 24; nb. 3; (2014); p. 695 - 707, View in Reaxys 6 of 58

Solvent (UV/VIS Spectroscopy)

acetonitrile

Absorption Maxima (UV/ 310; 228 VIS) [nm] Jenita, M. Jude; Mohandass; Rajendiran; Journal of Fluorescence; vol. 24; nb. 3; (2014); p. 695 - 707, View in Reaxys 7 of 58

Solvent (UV/VIS Spectroscopy)

isopropyl alcohol

Absorption Maxima (UV/ 310; 231; 216 VIS) [nm] Jenita, M. Jude; Mohandass; Rajendiran; Journal of Fluorescence; vol. 24; nb. 3; (2014); p. 695 - 707, View in Reaxys 8 of 58

Absorption Maxima (UV/ 308 VIS) [nm] Sanz, Miriam; Cadahia, Estrella; Esteruelas, Enrique; Munoz, Angel Ma; Fernandez De Simon, Brigida; Hernandez, Teresa; Estrella, Isabel; Journal of Agricultural and Food Chemistry; vol. 58; nb. 8; (2010); p. 4907 - 4914, View in Reaxys; Sanz, Miriam; Fernandez De Simon, Brigida; Esteruelas, Enrique; Munoz, Angel M; Cadahia, Estrella; Hernandez, Teresa; Estrella, Isabel; Pinto, Ernani; Journal of Agricultural and Food Chemistry; vol. 59; nb. 7; (2011); p. 3135 - 3145, View in Reaxys; Sanz, Miriam; De Simon, Brigida Fernandez; Cadahia, Estrella; Esteruelas, Enrique; Munoz, Angel M.; Hernandez, Teresa; Estrella, Isabel; Pinto, Ernani; Journal of Mass Spectrometry; vol. 47; nb. 7; (2012); p. 905 - 918, View in Reaxys

9 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Absorption Maxima (UV/ 308 VIS) [nm] Halaburgi, Vijaykumar M.; Sharma, Sujata; Sinha; Singh, Tej P.; Karegoudar, Timmanagouda B.; Process Biochemistry; vol. 46; nb. 5; (2011); p. 1146 - 1152, View in Reaxys 10 of 58

Absorption Maxima (UV/ 227; 307 VIS) [nm] Mohn, Tobias; Plitzko, Inken; Hamburger, Matthias; Phytochemistry; vol. 70; nb. 7; (2009); p. 924 - 934, View in Reaxys

11 of 58

Solvent (UV/VIS Spectroscopy)

ethanol

Absorption Maxima (UV/ 214; 309 VIS) [nm] Nakabayashi, Ryo; Kusano, Miyako; Kobayashi, Makoto; Tohge, Takayuki; Yonekura-Sakakibara, Keiko; Kogure, Noriyuki; Yamazaki, Mami; Kitajima, Mariko; Saito, Kazuki; Takayama, Hiromitsu; Phytochemistry; vol. 70; nb. 8; (2009); p. 1017 - 1029, View in Reaxys 12 of 58

Absorption Maxima (UV/ 231; 303 VIS) [nm] Schliemann, Willibald; Ammer, Christian; Strack, Dieter; Phytochemistry; vol. 69; nb. 1; (2008); p. 112 - 146, View in Reaxys

13 of 58

Solvent (UV/VIS Spectroscopy)

cyclohexane

Absorption Maxima (UV/ 288.3; 226.1; 217.4 VIS) [nm] Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 14 of 58

Solvent (UV/VIS Spectroscopy)

diethyl ether

Absorption Maxima (UV/ 310; 230.6 VIS) [nm]

33/130

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Ext./Abs. Coefficient [l·mol-1cm-1]

50118; 66069

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 15 of 58

Solvent (UV/VIS Spectroscopy)

dioxane

Absorption Maxima (UV/ 309; 230.6 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

60255; 79432

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 16 of 58

Solvent (UV/VIS Spectroscopy)

ethyl acetate

Absorption Maxima (UV/ 310; 230.4 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

52480; 66069

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 17 of 58

Solvent (UV/VIS Spectroscopy)

acetonitrile

Absorption Maxima (UV/ 310.4; 228.1 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

61659; 79432

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 18 of 58

Solvent (UV/VIS Spectroscopy)

2-methyl-butan-2-ol

Absorption Maxima (UV/ 310.2; 232.4 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

52480; 72443

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 19 of 58

Solvent (UV/VIS Spectroscopy)

propan-2-ol

Absorption Maxima (UV/ 310.4; 231.9; 216.5 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

56234; 67608; 75857

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 20 of 58

Solvent (UV/VIS Spectroscopy)

isobutanol

Absorption Maxima (UV/ 310.4; 232 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

52480; 69183

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

34/130

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21 of 58

Solvent (UV/VIS Spectroscopy)

2-methyl-propan-2-ol

Absorption Maxima (UV/ 310.2; 232.2; 216.4 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

67608; 75857; 81283

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 22 of 58

Solvent (UV/VIS Spectroscopy)

butan-1-ol

Absorption Maxima (UV/ 309; 231 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

53703; 70794

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 23 of 58

Solvent (UV/VIS Spectroscopy)

ethanol

Absorption Maxima (UV/ 308.5; 231; 215 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

14454; 17782; 20417

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 24 of 58

Solvent (UV/VIS Spectroscopy)

methanol

Absorption Maxima (UV/ 308.1; 254.6; 215.3 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

57543; 13489; 95499

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 25 of 58

Solvent (UV/VIS Spectroscopy)

neutral aq. solution

Absorption Maxima (UV/ 300; 217.5 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

33113; 60255

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 26 of 58

Solvent (UV/VIS Spectroscopy)

acidic aq. solution

Absorption Maxima (UV/ 315.4; 219 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

19054; 6309

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 27 of 58

Solvent (UV/VIS Spectroscopy)

alkaline aq. solution

Absorption Maxima (UV/ 371; 262; 251; 222 VIS) [nm]

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Ext./Abs. Coefficient [l·mol-1cm-1]

11220; 19054; 22387; 57543

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 28 of 58

Solvent (UV/VIS Spectroscopy)

micellar solution

Comment (UV/VIS Spectroscopy)

concentration dependence

Absorption Maxima (UV/ 304; 222 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

50118; 63095

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 29 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

neutral aq. solution

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 30 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

acidic aq. solution

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 31 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

alkaline aq. solution

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 32 of 58

Solvent (UV/VIS Spectroscopy)

ethanol; aq. HCl

Absorption Maxima (UV/ 440 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

15730

Medien; Zahran; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 178; nb. 5; (2003); p. 1069 - 1080, View in Reaxys 33 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

H2O

Comment (UV/VIS Spectroscopy)

Remark: pH 9.3

Panossian; Mamikonyan; Torosyan; Gabrielyan; Mkhitaryan; Analytical Chemistry; vol. 73; nb. 17; (2001); p. 4379 - 4383, View in Reaxys 34 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

H2O

36/130

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Cai; Arntfield; Charlton; JAOCS, Journal of the American Oil Chemists' Society; vol. 76; nb. 4; (1999); p. 433 441, View in Reaxys 35 of 58

Solvent (UV/VIS Spectroscopy)

H2O

Absorption Maxima (UV/ 220; 310 VIS) [nm] Cai; Arntfield; Charlton; JAOCS, Journal of the American Oil Chemists' Society; vol. 76; nb. 4; (1999); p. 433 441, View in Reaxys 36 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Lobbes; Fitznar; Kattner; Analytical Chemistry; vol. 71; nb. 15; (1999); p. 3008 - 3012, View in Reaxys 37 of 58

Solvent (UV/VIS Spectroscopy)

ethanol

Absorption Maxima (UV/ 215; 230; 305 VIS) [nm] Chen, Chung-Yi; Chang, Fang-Rong; Teng, Che-Ming; Wu, Yang-Chang; Journal of the Chinese Chemical Society; vol. 46; nb. 1; (1999); p. 77 - 86, View in Reaxys 38 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Absorption Maxima (UV/ 227; 309 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

5; 5

Kokpol, Udom; Chavasiri, Warinthorn; Chittawong, Vallapa; Bruce, Marc; Cunningham, G. N.; et al.; Phytochemistry (Elsevier); vol. 33; nb. 5; (1993); p. 1129 - 1132, View in Reaxys 39 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

various solvent(s); H2O

Absorption Maxima (UV/ 238 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

5129

Delay, Didier; Delmotte, Francis; Carbohydrate Research; vol. 198; nb. 2; (1990); p. 223 - 234, View in Reaxys 40 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

various solvent(s); H2O

Absorption Maxima (UV/ 265 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

1660

Delay, Didier; Delmotte, Francis; Carbohydrate Research; vol. 198; nb. 2; (1990); p. 223 - 234, View in Reaxys 41 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

various solvent(s); H2O

Absorption Maxima (UV/ 327 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

5248

Delay, Didier; Delmotte, Francis; Carbohydrate Research; vol. 198; nb. 2; (1990); p. 223 - 234, View in Reaxys

37/130

2017-10-08 12:35:19

42 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

ethanol

Absorption Maxima (UV/ 310; 231; 212 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

13100; 15980; 18500

Manchand, Percy S.; Belica, Peter S.; Wong, Harry S.; Synthetic Communications; vol. 20; nb. 17; (1990); p. 2659 - 2666, View in Reaxys 43 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Absorption Maxima (UV/ 309 VIS) [nm] Murao, Sawao; Arai, Motoo; Tanaka, Noriaki; Ishikawa, Hideshi; Matsumoto, Kunihiko; Watanabe, Susumu; Agricultural and Biological Chemistry; vol. 49; nb. 4; (1985); p. 981 - 986, View in Reaxys 44 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

aq. NaOH

Absorption Maxima (UV/ 218; 250; 364 VIS) [nm] Hartley, Roy D.; Keene, Annie S.; Phytochemistry (Elsevier); vol. 23; nb. 6; (1984); p. 1305 - 1308, View in Reaxys 45 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

methanol

Absorption Maxima (UV/ 214; 230; 306 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

19498; 16982; 19498

Hartley, Roy D.; Keene, Annie S.; Phytochemistry (Elsevier); vol. 23; nb. 6; (1984); p. 1305 - 1308, View in Reaxys 46 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

ethanol

Absorption Maxima (UV/ 280 VIS) [nm] Borges-Del-Castillo, Juan; Bradley-Delso, Antonio; Manresa-Ferrero, Ma. Teresa; Vazquez-Bueno, Purificacion; Rodriguez-Luis, Francisco; Phytochemistry (Elsevier); vol. 22; nb. 3; (1983); p. 782 - 783, View in Reaxys 47 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

ethanol

Absorption Maxima (UV/ 204; 220; 228; 233 VIS) [nm] Borges-Del-Castillo, Juan; Bradley-Delso, Antonio; Manresa-Ferrero, Ma. Teresa; Vazquez-Bueno, Purificacion; Rodriguez-Luis, Francisco; Phytochemistry (Elsevier); vol. 22; nb. 3; (1983); p. 782 - 783, View in Reaxys 48 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Solvent (UV/VIS Spectroscopy)

ethanol

38/130

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Absorption Maxima (UV/ 216; 231; 308 VIS) [nm] Ext./Abs. Coefficient [l·mol-1cm-1]

17000; 16000; 13000

Chiji, Hideyuki; Tanaka, Shigenori; Izawa, Masao; Agricultural and Biological Chemistry; vol. 44; nb. 1; (1980); p. 205 - 208, View in Reaxys 49 of 58

Description (UV/VIS Spectroscopy)

Absorption maxima

Santavy,F. et al.; Collection of Czechoslovak Chemical Communications; vol. 37; (1972); p. 1825 - 1850, View in Reaxys; Crowell et al.; Analytical Chemistry; vol. 35; (1963); p. 184, View in Reaxys; Yokota et al.; Yakugaku Zasshi; vol. 98; (1978); p. 1607,1608; Chem.Abstr.; vol. 90; nb. 135083h; (1979), View in Reaxys; Karpunin; J. Appl. Chem. USSR (Engl. Transl.); vol. 52; (1979); p. 1358,1286, View in Reaxys; Santavy et al.; Acta Universitatis Palackianae Olomucensis, Facultatis Medicae, Supplementum; vol. 13; (1973); p. 23; Chem.Abstr.; vol. 81; nb. 25219, View in Reaxys 50 of 58

Description (UV/VIS Spectroscopy)

UV/VIS

Skurikhin; Chemistry of Natural Compounds; vol. 3; (1967); p. 286; Khimiya Prirodnykh Soedinenii; vol. 3; (1967); p. 339, View in Reaxys 51 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

ethanol

Comment (UV/VIS Spectroscopy)

220 - 360 nm

Aulin-Erdtman; Hegbom; Svensk Papperstidning; vol. 60; (1957); p. 671,673, 676, View in Reaxys 52 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

H2O

Comment (UV/VIS Spectroscopy)

220 - 360 nm

Aulin-Erdtman; Hegbom; Svensk Papperstidning; vol. 60; (1957); p. 671,673, 676, View in Reaxys 53 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

aq. NaOH

Comment (UV/VIS Spectroscopy)

220 - 420 nm

Aulin-Erdtman; Hegbom; Svensk Papperstidning; vol. 60; (1957); p. 671,673, 676, View in Reaxys 54 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

NaOH / ethanol

Comment (UV/VIS Spectroscopy)

220 - 420 nm

Aulin-Erdtman; Hegbom; Svensk Papperstidning; vol. 60; (1957); p. 671,673, 676, View in Reaxys 55 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

ethanol

Comment (UV/VIS Spectroscopy)

210 - 340 nm

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Pearl; Beyer; Journal of the American Chemical Society; vol. 72; (1950); p. 1743,1746, View in Reaxys; McIvor; Pepper; Canadian Journal of Chemistry; vol. 31; (1953); p. 298,300, View in Reaxys 56 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

dioxane

Pearl; Journal of the American Chemical Society; vol. 70; (1948); p. 1746, View in Reaxys 57 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

ethanol

Patterson; Hibbert; Journal of the American Chemical Society; vol. 65; (1943); p. 1862,1864, View in Reaxys; Lemon; Journal of the American Chemical Society; vol. 69; (1947); p. 2998, View in Reaxys 58 of 58

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

KOH / ethanol

Lemon; Journal of the American Chemical Society; vol. 69; (1947); p. 2998, View in Reaxys ESR Spectroscopy (1) 1 of 1

Description (ESR Spectroscopy)

ESR

Ciaramitaro,D.; Steelink,C.; Phytochemistry (Elsevier); vol. 14; (1975); p. 543 - 552, View in Reaxys Raman Spectroscopy (1) Description (Ram- References an Spectroscopy) Spectrum

Saariaho, Anna-Maija; Jaeaeskelaeinen, Anna-Stiina; Nuopponen, Mari; Vuorinen, Tapani; Applied Spectroscopy; vol. 57; nb. 1; (2003); p. 58 - 66, View in Reaxys

Fluorescence Spectroscopy (27) Description (Fluo- Solvent (Fluoresrescence Speccence Spectrotroscopy) scopy)

Temperature (Flu- Comment (Fluoorescence Spec- rescence Spectroscopy) [°C] troscopy)

References

Spectrum

micellar solution

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Spectrum

cyclohexane

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Spectrum

ethyl acetate

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Spectrum

acetonitrile

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Spectrum

2-methyl-propan-2-ol

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Spectrum

propan-2-ol

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Spectrum

methanol

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy;

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vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys Spectrum

neutral aq. solution

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Spectrum

alkaline aq. solution

Maxima

cyclohexane

Maxima

diethyl ether

Maxima

ethyl acetate

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Maxima

acetonitrile

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Maxima

2-methyl-butan-2ol

Maxima

2-methyl-propan-2-ol

Maxima

isobutanol

Maxima

propan-2-ol

Maxima

butan-1-ol

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Maxima

ethanol

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Maxima

methanol

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Maxima

neutral aq. solution

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Maxima

acidic aq. solution

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys 29.85

29.85

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy;

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vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys Maxima

alkaline aq. solution

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Fluorescence excitation spectrum

neutral solution

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

solvent dependence

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Spectrum

H2O; dioxane

Maxima

micellar solution

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Maxima

dioxane

Stalin; Rajendiran; Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy; vol. 61; nb. 13-14; (2005); p. 3087 - 3096, View in Reaxys

Exposure Assessment (2) Exposure Sources presence in PM2.5 samples of emissions from prescribed burnings (Nevada Great Basin, and Toiyabye National Forest, NV), wildland fuel, simulated residential wood and agricultural combustions

References

biomass combus- Mazzoleni, Lynn R.; Zielinska, Barbara; Moosmueller, Hans; Environmental Science tion; pyrolysis and Technology; vol. 41; nb. 7; (2007); p. 2115 - 2122, View in Reaxys products arising from cellulose, lignin and resins

formation and oxidation of presence in water aquatic humic and fulvic acids from the Wakarusa river and Clinton Lake, USA (1996)

Pomes; Larive; Thurman; Green; Orem; Rostad; Coplen; Cutak; Dixon; Environmental Science and Technology; vol. 34; nb. 20; (2000); p. 4278 - 4286, View in Reaxys

Concentration in the Environment (25) 1 of 25

Media (Concentration in the Environment)

industrial boiler emission, particle phase

Location

Guangzhou, Beijing, China

Contamination Concentration

21.8 ng/mg

Method, Remarks (Concentration in the Environment)

emissions of mixed coal combustion from diff. combustion plants collec. with dilution samplers; ultrasonic extrac. with CH2Cl2:CH3OH (3:1, v/v); derivatized by BSTFA; GC/MS; emission factor: mass ratio of particulate matter emitted and fuel consumption

Zhang, Yuanxun; Schauer, James Jay; Zhang, Yuanhang; Zeng, Limin; Wei, Yongjie; Liu, Yuan; Shao, Min; Environmental Science and Technology; vol. 42; nb. 14; (2008); p. 5068 - 5073, View in Reaxys 2 of 25

Media (Concentration in the Environment)

residential stove emission, particle phase

Location

Gubeikou, Beijing, China

Contamination Concentration

32.9 ng/mg

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Method, Remarks (Concentration in the Environment)

emissions of bituminite combustion collected at chimney outlet downwind in plume; ultrasonic extrac. with dichlormethane:methanol (3:1, v/v); derivatized by BSTFA; GC/MS; emission factor: mass ratio of particulate matter emitted and fuel consumption

Media (Concentration in the Environment)

residential stove emission, particle phase

Location

Gubeikou, Beijing, China

Contamination Concentration

290.8 ng/mg

Method, Remarks (Concentration in the Environment)

emissions of anthracite combustion collec. at chimney outlet downwind in plume; ultrasonic extrac. with dichlormethane:methanol (3:1, v/v); derivatized by BSTFA; GC/MS; emission factor: mass ratio of particulate matter emitted and fuel consumption

Media (Concentration in the Environment)

residential stove emission, particle phase

Location

Beijing, China

Contamination Concentration

54.6 ng/mg

Method, Remarks (Concentration in the Environment)

emissions of coal brinquette combustion collec. from steel stove with refractory line chamber; ultrasonic extrac. with CH2Cl2:CH3OH (3:1, v/v); derivatized by BSTFA; GC/MS; emission factor: mass ratio of particulate matter emitted and fuel consumption

Species (Concentration in the Environment)

human

Location

San Marcos, Guatemala

Contamination Concentration

0.039 μg/mg creatinine

Background Concentration

0.012 μg/mg creatinine

Method, Remarks (Concentration in the Environment)

mean conc.; in urine; first urination samples collected after midnight for 2 consecutive days from mothers who used wood burning for cooking; ion exchange solid-phase extraction; GC/MS/SIM; conc. normalized to creatinine; table

Clark, Michael; Paulsen, Michael; Smith, Kirk R.; Canuz, Eduardo; Simpson, Christopher D.; Environmental Science and Technology; vol. 41; nb. 10; (2007); p. 3481 - 3487, View in Reaxys 6 of 25

Species (Concentration in the Environment)

human

Location

San Marcos, Guatemala

Contamination Concentration

0.025 μg/mg creatinine

Background Concentration

0.012 μg/mg creatinine

Method, Remarks (Concentration in the Environment)

mean conc.; in urine; first urination samples collected after midnight for 2 consecutive days from non-mothers who used wood burning for cooking; ion exchange solid-phase extraction; GC/MS/SIM; conc. normalized to creatinine; table

Clark, Michael; Paulsen, Michael; Smith, Kirk R.; Canuz, Eduardo; Simpson, Christopher D.; Environmental Science and Technology; vol. 41; nb. 10; (2007); p. 3481 - 3487, View in Reaxys 7 of 25

Species (Concentration in the Environment)

human

Location

San Marcos, Guatemala

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Contamination Concentration

0.026 μg/mg creatinine

Background Concentration

0.012 μg/mg creatinine

Method, Remarks (Concentration in the Environment)

mean conc.; in urine; first urination samples collected after midnight for 2 consecutive days from mothers who used ventilated cook stoves; ion exchange solid-phase extraction; GC/MS/SIM; conc. normalized to creatinine; table

Clark, Michael; Paulsen, Michael; Smith, Kirk R.; Canuz, Eduardo; Simpson, Christopher D.; Environmental Science and Technology; vol. 41; nb. 10; (2007); p. 3481 - 3487, View in Reaxys 8 of 25

Species (Concentration in the Environment)

human

Location

San Marcos, Guatemala

Contamination Concentration

0.042 μg/mg creatinine

Background Concentration

0.012 μg/mg creatinine

Method, Remarks (Concentration in the Environment)

mean conc.; in urine; first urination samples collected after midnight for 2 consecutive days from non-mothers who used ventilated cook stoves; ion exchange solid-phase extraction; GC/MS/SIM; conc. normalized to creatinine; table

Clark, Michael; Paulsen, Michael; Smith, Kirk R.; Canuz, Eduardo; Simpson, Christopher D.; Environmental Science and Technology; vol. 41; nb. 10; (2007); p. 3481 - 3487, View in Reaxys 9 of 25

Media (Concentration in the Environment)

smoke

Location

Research Triangle Park, North Carolina

Contamination Concentration

0.46 μg mg-1 PM2.5

Method, Remarks (Concentration in the Environment)

PM2.5 samples collected from smoke during combustion of wheat (Triticum aestivum L.) stubble in chamber experiment using low volume sampler; summer 2004 at U.S. EPA test burn facility; extracted by sonication; GC-MS in SIM; table

Jimenez, Jorge R.; Claiborn, Candis S.; Dhammapaia, Ranil S.; Simpson, Christopher D.; Environmental Science and Technology; vol. 41; nb. 22; (2007); p. 7824 - 7829, View in Reaxys 10 of 25

Media (Concentration in the Environment)

smoke

Location

eastern Washington and northern Idaho

Contamination Concentration

1.00 μg mg-1 PM2.5

Method, Remarks (Concentration in the Environment)

PM2.5 samples collected from smoke during combustion of wheat (Triticum aestivum L.) stubble in field experiment using low volume sampler; fall 2004 and spring 2005; extracted by sonication; GC-MS in SIM; table

Jimenez, Jorge R.; Claiborn, Candis S.; Dhammapaia, Ranil S.; Simpson, Christopher D.; Environmental Science and Technology; vol. 41; nb. 22; (2007); p. 7824 - 7829, View in Reaxys 11 of 25

Media (Concentration in the Environment)

smoke

Location

eastern Washington and northern Idaho

Contamination Concentration

0.24 μg mg-1 PM2.5

Method, Remarks (Concentration in the Environment)

PM2.5 samples collected from smoke during combustion of Kentucky bluegrass (Poa pratensis L.) stubble in field experiment using low volume sampler; fall 2004 and spring 2005; extracted by sonication; GC-MS in SIM; table

Jimenez, Jorge R.; Claiborn, Candis S.; Dhammapaia, Ranil S.; Simpson, Christopher D.; Environmental Science and Technology; vol. 41; nb. 22; (2007); p. 7824 - 7829, View in Reaxys 12 of 25

Media (Concentration in the Environment)

air

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Location

Beacon Hill, Seattle, WA, USA

Contamination Concentration

0.42 pg/l

Method, Remarks (Concentration in the Environment)

mean conc. in ambient atmospheric particulate matter PM10; 9 24-h integrated samples collected between October 25, 1999 and January 2001; urban area; GC/MS analysis

Simpson, Christopher D.; Paulsen, Michael; Dills, Russell L.; Liu, L.-J. Sally; Kalman, David A.; Environmental Science and Technology; vol. 39; nb. 2; (2005); p. 631 - 637, View in Reaxys 13 of 25

Media (Concentration in the Environment)

air

Location

Beacon Hill, Seattle, WA, USA

Contamination Concentration

0.38 pg/l

Method, Remarks (Concentration in the Environment)

mean conc. in ambient atmospheric fine particulate matter PM2.5; 9 24-h integrated samples collected between October 25, 1999 and January 2001; urban area; GC/MS analysis

Simpson, Christopher D.; Paulsen, Michael; Dills, Russell L.; Liu, L.-J. Sally; Kalman, David A.; Environmental Science and Technology; vol. 39; nb. 2; (2005); p. 631 - 637, View in Reaxys 14 of 25

Media (Concentration in the Environment)

air

Location

Beacon Hill, Seattle, WA, USA

Contamination Concentration

0.17 - 1.47 pg/l

Method, Remarks (Concentration in the Environment)

in ambient atmospheric fine particulate matter PM2.5; 6 24-h integrated indoor samples collected between October 25, 1999 and January 2001; urban area; GC/MS analysis

Simpson, Christopher D.; Paulsen, Michael; Dills, Russell L.; Liu, L.-J. Sally; Kalman, David A.; Environmental Science and Technology; vol. 39; nb. 2; (2005); p. 631 - 637, View in Reaxys 15 of 25

Media (Concentration in the Environment)

air

Location

Beacon Hill, Seattle, WA, USA

Contamination Concentration

0.19 - 1.66 pg/l

Method, Remarks (Concentration in the Environment)

in ambient atmospheric particulate matter PM10; 6 24-h integrated indoor samples collected between October 25, 1999 and January 2001; urban area; GC/MS analysis

Simpson, Christopher D.; Paulsen, Michael; Dills, Russell L.; Liu, L.-J. Sally; Kalman, David A.; Environmental Science and Technology; vol. 39; nb. 2; (2005); p. 631 - 637, View in Reaxys 16 of 25

Media (Concentration in the Environment)

air

Location

Beacon Hill, Seattle, WA, USA

Contamination Concentration

0.09 - 0.27 pg/l

Method, Remarks (Concentration in the Environment)

in ambient atmospheric particulate matter PM10; 3 24-h integrated outdoor samples collected between October 25, 1999 and January 2001; urban area; GC/MS analysis

Simpson, Christopher D.; Paulsen, Michael; Dills, Russell L.; Liu, L.-J. Sally; Kalman, David A.; Environmental Science and Technology; vol. 39; nb. 2; (2005); p. 631 - 637, View in Reaxys 17 of 25

Media (Concentration in the Environment)

air

Location

Beacon Hill, Seattle, WA, USA

Contamination Concentration

0.1 - 0.22 pg/l

45/130

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Method, Remarks (Concentration in the Environment)

in ambient atmospheric fine particulate matter PM2.5; 3 24-h integrated outdoor samples collected between October 25, 1999 and January 2001; urban area; GC/MS analysis

Simpson, Christopher D.; Paulsen, Michael; Dills, Russell L.; Liu, L.-J. Sally; Kalman, David A.; Environmental Science and Technology; vol. 39; nb. 2; (2005); p. 631 - 637, View in Reaxys 18 of 25

Media (Concentration in the Environment)

air

Location

Beacon Hill, Seattle, WA, USA

Contamination Concentration

0.08 - 1.52 pg/l

Method, Remarks (Concentration in the Environment)

in ambient atmospheric fine particulate matter PM2.5; median conc.: 0.61 pg/l; 10 24-h integrated samples collected between October 25, 1999 and January 2001; urban area; GC/MS analysis

Simpson, Christopher D.; Paulsen, Michael; Dills, Russell L.; Liu, L.-J. Sally; Kalman, David A.; Environmental Science and Technology; vol. 39; nb. 2; (2005); p. 631 - 637, View in Reaxys 19 of 25

Media (Concentration in the Environment)

air

Location

San Joaquin Valley, California (USA)

Contamination Concentration

0.1 - 23 pg/l

Method, Remarks (Concentration in the Environment)

atmospheric fine particulate matter samples collected daily from December 5, 1995 to January 6, 1996, fine particle (dp <3 μm) samples collected at the Kern Wildlife Refuge and at urban sites in Bakersfield and Fresno; GC/MS analyses (TMS derivative)

Nolte, Christopher G.; Schauer, James J.; Cass, Glen R.; Simoneit, Bernd R.T.; Environmental Science and Technology; vol. 35; nb. 10; (2001); p. 1912 - 1919, View in Reaxys 20 of 25

Species (Concentration in the Environment)

eucalyptus

Contamination Concentration

41 mg/kg

Method, Remarks (Concentration in the Environment)

emission rate determined; wood combustion test; fine aerosol samples collected ca. 5 m above the fireplate grate; GC/MS analyses (TMS derivative)

Nolte, Christopher G.; Schauer, James J.; Cass, Glen R.; Simoneit, Bernd R.T.; Environmental Science and Technology; vol. 35; nb. 10; (2001); p. 1912 - 1919, View in Reaxys 21 of 25

Species (Concentration in the Environment)

oak

Contamination Concentration

35 mg/kg

Method, Remarks (Concentration in the Environment)

emission rate determined; wood combustion test; fine aerosol samples collected ca. 5 m above the fireplate grate; GC/MS analyses (TMS derivative)

Nolte, Christopher G.; Schauer, James J.; Cass, Glen R.; Simoneit, Bernd R.T.; Environmental Science and Technology; vol. 35; nb. 10; (2001); p. 1912 - 1919, View in Reaxys 22 of 25

Media (Concentration in the Environment)

ambient air

Location

San Joaquin Valley, California, USA

Contamination Concentration

10.8 - 135 pg/l

Background Concentration

0.335 - 0.442 pg/l

Method, Remarks (Concentration in the Environment)

in fine particle phase; 24-h samples collected on 26-28 December 1995 and 4-6 January 1996 by high-volume dichotomous virtual impactors at two urban sites (Fresno and Bakersfield); background site: Kern Wildlife Refuge; extract.; GC-MS anal.

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Schauer, James J.; Cass, Glen R.; Environmental Science and Technology; vol. 34; nb. 9; (2000); p. 1821 - 1832, View in Reaxys 23 of 25

Species (Concentration in the Environment)

Posidonia oceanica

Location

Western Mediterranian Sea

Background Concentration

3.9 - 8 mg/g dry wt

Method, Remarks (Concentration in the Environment)

detd. in intermediate and adult leaf sheaths and in adult leaf blades; collected May 1996; some variability depending on location of collecting; maximum concn. (8 mg/g dry wt) in adult blades collected near Figari (Corsica)

Agostini, Sylvia; Desjobert, Jean-Marie; Pergent, Gerard; Phytochemistry; vol. 48; nb. 4; (1998); p. 611 - 617, View in Reaxys 24 of 25

Media (Concentration in the Environment)

burning emission

Location

Southern California, USA

Contamination Concentration

15.86 - 66.61 mg/kg burned

Method, Remarks (Concentration in the Environment)

emissions from the combustions of oak wood and synthetic logs in residential fireplaces; GC-MS analysis

Rogge, Wolfgang F.; Hildemann, Lynn M.; Mazurek, Monica A.; Cass, Glen R.; Simoneit, Bernd R. T.; Environmental Science and Technology; vol. 32; nb. 1; (1998); p. 13 - 22, View in Reaxys 25 of 25

Media (Concentration in the Environment)

smoke

Location

70 km north of Manaus, Amazonia

Contamination Concentration

4.1 ng/l

Method, Remarks (Concentration in the Environment)

smoke from burning forest litter; in northern forest reserve of Instituto Nacional de Pesquisas da Amazonia; November 1992; high volume filtration; extraction with CH2Cl2; methylation; separation by TLC; GC and GC-MS analysis

Radzi bin Abas, M.; Simoneit, B. R. T.; Elias, V.; Cabral, J. A.; Cardoso, J. N.; Chemosphere; vol. 30; nb. 5; (1995); p. 995 - 1016, View in Reaxys Abiotic Degradation, Hydrolysis (1) 1 of 1

Type (Abiotic Degradation, Hydrolysis)

oxidative transformation

Concentration (Abiotic Degradation, Hydrolysis)

0.3 mmol/l

Degradation Rate (Abio- Ca. 85 - 95 percent tic Degradation, Hydrolysis) [%] Exposure Period (Abiotic Degradation, Hydrolysis)

pH-Value (Abiotic Degradation, Hydrolysis)

5.6

Method, Remarks (Abio- in the presence of laccase with or without addition of 4-chlorophenol or 4-chloroaniline; tic Degradation, Hydrol- centrifugation; supernatant filtration; HPLC analysis ysis) Park, Jong-Woo; Dec, Jerzy; Kim, Jang-Eok; Bollag, Jean-Marc; Environmental Science and Technology; vol. 33; nb. 12; (1999); p. 2028 - 2034, View in Reaxys Use (2) Use Pattern

References

47/130

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diabetes

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys

Dyeing keratin fibers

Patent; Wella AG; US7214248; (2007); (B1) English, View in Reaxys

Isolation from Natural Product (137) Isolation from Location Comment (IsolaNatural Product tion from Natural Product) fruits of Scaevola taccada were collected from Satun Province, Thailand, in December 2014 root bark of Morus australis; collected at Tainan, Taiwan

References

Suthiwong, Jittra; Thongsri, Yordhathai; Yenjai, Chavi; Natural Product Research; vol. 31; nb. 4; (2017); p. 453 - 459, View in Reaxys

supporting information

Liao, Yu-Ren; Kuo, Ping-Chung; Tsai, Wei-Jern; Huang, GuanJhong; Lee, Kuo-Hsiung; Wu, Tian-Shung; Bioorganic and Medicinal Chemistry Letters; vol. 27; nb. 2; (2017); p. 309 - 313, View in Reaxys

root barks of Ilex rotunda Thunb.; purchased from Guangdong Province, P. R. China

Liu, Wei-Jie; Peng, Yu-Yuan; Chen, Hao; Liu, Xian-Fang; Liang, Jing-Yu; Sun, Jian-Bo; Chemistry and Biodiversity; vol. 14; nb. 2; (2017); Art.No: E1600209, View in Reaxys

whole plant of Pholidota cantonensis, collected in Suining County Hunan Province, China, in October 2011

Li, Bin; Ali, Zulfiqar; Chan, Michael; Li, Juan; Wang, Mei; Abe, Naohito; Wu, Can-Rong; Khan, Ikhlas A.; Wang, Wei; Li, ShunXiang; Phytochemistry; vol. 137; (2017); p. 132 - 138, View in Reaxys

air-dried stems of Hydrangea paniculata; collected from the County of Jinxiu, Guangxi Zhuang Autonomous Region, China, May 2009

Ma, Jie; Sun, Hua; Li, Chuang-Jun; Yang, Jing-Zhi; Chen, FangYou; Zhang, Dong-Ming; Journal of Asian Natural Products Research; vol. 19; nb. 6; (2017); p. 564 - 571, View in Reaxys

leaves and stems of Microcos tomentosa; collected in Khao Hin Son Royal Development Study Centre, Chachoengsao, Thailand, October 2012

Somwong, Pathom; Suttisri, Rutt; Amnuoypol, Surattana; Chemistry of Natural Compounds; vol. 53; nb. 2; (2017); p. 394 - 395; Khim. Prir. Soedin.; vol. 53; nb. 2; (2017); p. 331 - 332,2, View in Reaxys

roots of Taraxacum coreanum; obtained from the local herbal market in Chungbuk (Korea)

Mo, Eun Jin; Ahn, Jong Hoon; Jo, Yang Hee; Kim, Seon Beom; Hwang, Bang Yeon; Lee, Mi Kyeong; Molecules; vol. 22; nb. 8; (2017); Art.No: 1349, View in Reaxys

dried wood of Simira grazielae; collected in the forest reserve of Companhia Vale do Rio Doce, Linhares City, Espirito Santo State, Brazil

Sanches; Chaves; Carvalho; Araujo; Vieira; Braz-Filho; Chemistry of Natural Compounds; vol. 53; nb. 3; (2017); p. 543 - 544; Khim. Prir. Soedin.; nb. 3; (2017); p. 461 - 462,2, View in Reaxys

48/130

2017-10-08 12:35:19

root of Rennellia elliptica Korth; collected in Endau Rompin State Park, Pahang, Malaysia

Osman, Che Puteh; Ismail, Nor Hadiani; Wibowo, Agustono; Ahmad, Rohaya; Phytochemistry Letters; vol. 16; (2016); p. 225 - 229, View in Reaxys

stem bark of Fagraea fragrans Roxb.; collected from Che Bilang, Muang Satun, Satun Province, south of Thailand, May, 2012

Madmanang, Suwaibah; Cheyeng, Naseebah; Heembenmad, Sareefah; Mahabusarakam, Wilawan; Saising, Jongkon; Seeger, Markus; Chusri, Sasitorn; Chakthong, Suda; Journal of Natural Products; vol. 79; nb. 4; (2016); p. 767 - 774, View in Reaxys

aerial parts of Asterothamnus centali-asiaticus; collected in Xunhua, China

Wang, Yan-Ming; Zhao, Jian-Qiang; Zhou, Shuang-Yan; Yang, Jun-Li; Yao, Xiao-Jun; Tao, Yan-Duo; Mei, Li-Juan; Shi, YanPing; Tetrahedron; vol. 72; nb. 32; (2016); p. 4910 - 4917, View in Reaxys

whole plant of Artemisia austroyunnanensis; collected in October 2012 from Sipsongpanna of Yunnan, China

Chi, Jun; Li, Bao-Cai; Yang, Bo-Tao; Zhang, Mi; Journal of the Chemical Society of Pakistan; vol. 38; nb. 3; (2016); p. 533 - 537, View in Reaxys

fruits of Phyllanthus emblica; purchased from ShandongTraditional Chinese Medicine Hospital

Zhang, Yao; Zhao, Lijuan; Guo, Xiaojiang; Li, Chao; Li, Haizhen; Lou, Hongxiang; Ren, Dongmei; Archives of Pharmacal Research; vol. 39; nb. 9; (2016); p. 1202 - 1211, View in Reaxys

aerial parts of Morinda parvifolia; collected from Hainan Province, China

Kang, Jie; Zhang, Peng; Gao, Zengping; Zhang, Jian; Yan, Zheng; Wang, Hongqing; Chen, Ruoyun; Phytochemistry; vol. 130; (2016); p. 144 - 151, View in Reaxys

roots of Coixlachryma-jobi L. var. ma-yuen Stapf.; collected at Yeoncheon-gun, Gyeonggi-do, Korea

Hong, Seong Su; Choi, Chun Whan; Choi, Yun-Hyeok; Oh, Joa Sub; Phytochemistry Letters; vol. 17; (2016); p. 152 - 157, View in Reaxys

whole plants of Phaius mishmensis (Orchidaceae); collected from Nanto Hsien, Taiwan

Jao, Chen-Wei; Hung, Tzu-Heng; Chang, Chi-Fen; Chuang, TaHsien; Molecules; vol. 21; nb. 11; (2016); Art.No: 1605, View in Reaxys

stems of Alyxia schlechteri; collected in Phu Wiang District, Khon Kaen Province, Thailand

Sribuhom, Thurdpong; Sriphana, Uraiwan; Thongsri, Yordhathai; Yenjai, Chavi; Phytochemistry Letters; vol. 11; (2015); p. 80 84, View in Reaxys

stem bark of Garcinia amplexicaulis Vieill. ex Pierre, collected in July 1998, in the Fort Cache region in southern New Caledonia

Lavaud, Alexis; Richomme, Pascal; Gatto, Julia; Aumond, MarieChristine; Poullain, Cyril; Litaudon, Marc; Andriantsitohaina, Ramaroson; Guilet, David; Phytochemistry; vol. 109; (2015); p. 103 - 110, View in Reaxys

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fruits of Pandanus supporting infortectorius Parkinmation son ex Du Roi; collected in Binh Thuan province, Vietnam, February 2013

Mai, Dinh Tri; Le, Tien Dung; Nguyen, Tan Phat; Phan, Nhat Minh; Nguyen, Huu An; Nguyen, Thi Thanh Phuc; Tran, Le Quan; Natural Product Research; vol. 29; nb. 15; (2015); p. 1437 - 1441, View in Reaxys

eucalyptus globulus wood chips

Araya, Fabio; Troncoso, Eduardo; Mendonça, Regis Teixeira; Freer, Juanita; Rencoret, Jorge; Del Río, José Carlos; Journal of the Chilean Chemical Society; vol. 60; nb. 2; (2015); p. 2954 - 2960, View in Reaxys

seeds of Raphanus sativus; purchased at the Kyungdong herbal market, Seoul, Korea, in January 2010

Kim, Ki Hyun; Moon, Eunjung; Lee, Seoung Rak; Park, Kyoung Jin; Kim, Sun Yeou; Choi, Sang Un; Lee, Kang Ro; Journal of the Brazilian Chemical Society; vol. 26; nb. 11; (2015); p. 2307 - 2312, View in Reaxys

Elaeocarpus braceanus: collected in Xishuangbanna, Yunnan, China, October, 2009

Wang, Huan-Qin; Peng, Chao-Zhong; Chen, Ye-Gao; Chemistry of Natural Compounds; vol. 51; nb. 6; (2015); p. 1167 - 1168; Khim. Prir. Soedin.; vol. 6; (2015); p. 1004 - 1005,2, View in Reaxys

twigs of Feroniella lucida (Scheff.); collected in Songkhla Province, Thailand

Sriyatep, Teerayut; Chakthong, Suda; Leejae, Sukanlaya; Voravuthikunchai, Supayang P.; Tetrahedron; vol. 70; nb. 9; (2014); p. 1773 - 1779, View in Reaxys

the roots of Drypetes hoaensis (Euphorbiaceae); collected from the forest at Sakaerat, Nakhon Ratchasima province, Thailand

Wittayalai, Sawangjitt; Mahidol, Chulabhorn; Prachyawarakorn, Vilailak; Prawat, Hunsa; Ruchirawat, Somsak; Phytochemistry; vol. 99; (2014); p. 121 - 126, View in Reaxys

leaves of Liriodendron tulipifera, American tulip tree; collected from Chiayi County, Taiwan

Kang, Ya-Fei; Liu, Chi-Ming; Kao, Chiu-Li; Chen, Chung-Yi; Molecules; vol. 19; nb. 4; (2014); p. 4235 - 4245, View in Reaxys

whole plants of Artemisia capillaris Thunb.; collected in Chengcheng County, Shaanxi Province, China

Zhao, Yong; Geng, Chang-An; Sun, Chang-Li; Ma, Yun-Bao; Huang, Xiao-Yan; Cao, Tuan-Wu; He, Kang; Wang, Hao; Zhang, Xue-Mei; Chen, Ji-Jun; Fitoterapia; vol. 95; (2014); p. 187 - 193, View in Reaxys

leaves and stems of Clerodendron trichotomum; collected from Tonglin County, Anhui Province, october 2011

Lu, Rui-Li; Hu, Feng-Lin; Bao, Guan-Hu; Chemistry of Natural Compounds; vol. 50; nb. 1; (2014); p. 65 - 67; Khim. Prir. Soedin.; nb. 1; (2014); p. 62 - 63,2, View in Reaxys

stems of Celastrus monospermus Roxb; collected from Xishuangbanna, Yunnan Province, China, July 2010

50/130

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orchid Dendrobium sinense T. Tang et F. T. Wang; collected in Baisha County of Hainan Island, China Aletris Spicata

Chen, Xiu-Juan; Mei, Wen-Li; Cai, Cai-Hong; Guo, Zhi-Kai; Song, Xi-Qiang; Dai, Hao-Fu; Phytochemistry Letters; vol. 9; nb. 1; (2014); p. 107 - 112, View in Reaxys

supporting information

Li, Lin-Zhen; Wang, Meng-Hua; Sun, Jian-Bo; Liang, Jing-Yu; Natural Product Research; vol. 28; nb. 15; (2014); p. 1214 - 1217, View in Reaxys

aerial part of Cirsium souliei; collected in the North Mountains of Huzhu Country in Qinghai Provice, P. R. China

He, Xiao-Feng; He, Zi-Wei; Jin, Xiao-Jie; Pang, Xiao-Yan; Gao, Jing-Guo; Yao, Xiao-Jun; Zhu, Ying; Phytochemistry Letters; vol. 10; nb. 1; (2014); p. 80 - 85, View in Reaxys

aerial part of Cirsium souliei, Asteraceae family (or Compositae), tribe Cynareae; collected in mountain areas ataltitudes of 2200–2500 m in North Mountains of Huzhu Countyin Qinghai Province, P.R. China, 2001

He, Xiao-Feng; He, Zi-Wei; Jin, Xiao-Jie; Pang, Xiao-Yan; Gao, Jing-Guo; Yao, Xiao-Jun; Zhu, Ying; Phytochemistry Letters; vol. 10; (2014); p. 80 - 85, View in Reaxys

whole plant of Croton tonkinensis Gagnep; collected from Vietnam

supporting information

Kuo, Ping-Chung; Yang, Mei-Lin; Hwang, Tsong-Long; Lai, YuanYu; Li, Yue-Chiun; Thang, Tran Dinh; Wu, Tian-Shung; Journal of Natural Products; vol. 76; nb. 2; (2013); p. 230 - 236, View in Reaxys

twig of Liriodendron tulipifera; collected in Chiayi County, Taiwan, December, 2007

Lee, Chien-Hsing; Chen, Hsin-Liang; Hong, Zi-Ling; Hsieh, Chiao-Wei; Juan, Sun-Wen; Huang, Jin-Cherng; Wang, Hui-Min; Chen, Chung-Yi; Chemistry of Natural Compounds; vol. 49; nb. 2; (2013); p. 398 - 400; Khim. Prir. Soedin.; vol. 2; (2013); p. 335 336,2, View in Reaxys

stems and leaves of Euonymus acanthocarpus; collected in Xishuangbanna, Yunnan Province, P. R. China, August, 2010

steam of Dendropanax dentiger (Harms) Merr. (Araliaceae); collected in Jiang Xi Province, China

Zheng, Li-Ping; He, Zhi-Gao; Asian Journal of Chemistry; vol. 25; nb. 14; (2013); p. 7809 - 7812, View in Reaxys

stems of Celastrus rugosus; collected from Xishuangbanna of Yunnan Province, China in August, 2010

Chang, Ruijie; Wang, Chunhui; Zeng, Qi; Guan, Bin; Zhang, Weidong; Jin, Huizi; Archives of Pharmacal Research; vol. 36; nb. 11; (2013); p. 1291 - 1301, View in Reaxys

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roots of Premna tomentosa; collected from Thirumala hills, Andhra Pradesh

Ayinampudi, Sridhar Rao; Domala, Ramesh; Merugu, Ramchander; Bathula, Sreenivasulu; Janaswamy, Madhusudana Rao; Fitoterapia; vol. 83; nb. 1; (2012); p. 88 - 92, View in Reaxys

stem bark of Stereospermum acuminatissimum K. Schum; collected at Bandjoun in west province of Cameroon

Ramsay, Kamdem Soup T.; Wafo, Pascal; Ali, Zulfiqar; Khan, Ajmal; Oluyemisi, Ogbole O.; Marasini, Bishnu P.; Khan, Ikhlas A.; Bonaventure, Ngadjui T.; Choudhary, M. Iqbal; Atta-Ur-Rahman; Fitoterapia; vol. 83; nb. 1; (2012); p. 204 - 208, View in Reaxys

leaves and twigs of Gardenia carinata Wall. (Rubiaceae); collected from Narathiwat province of Thailand

Kongkum, Naowarat; Tuchinda, Patoomratana; Pohmakotr, Manat; Reutrakul, Vichai; Piyachaturawat, Pawinee; Jariyawat, Surawat; Suksen, Kanoknetr; Yoosook, Chalobon; Kasisit, Jitra; Napaswad, Chanita; Fitoterapia; vol. 83; nb. 2; (2012); p. 368 - 372, View in Reaxys

maple syrup, Page/Page colchromatography Quebec (Canada) umn 38-40; 48-50 on a Sephadex. (TM). LH-20 column (4.5 x 64 cm), eluting with a gradient system of MeOH: H20 (3:7 v/v to 7:3 v/v to 100:0 v/v), and then with acetone: H20 (7:3 v/v); chromatography on Waters Sunfire Prep. (TM). Ci6 column (250 x 10 mm i.d., 5 μπν, flow 2 mUmin) and eluting with a MeOH:H20 gradient system

Casearia grewiifolia; collected in Ubon Ratchathani, Thailand

Rayanil, Kanok-On; Nimnoun, Chanisara; Tuntiwachwuttikul, Pittaya; Phytochemistry Letters; vol. 5; nb. 1; (2012); p. 59 - 62, View in Reaxys

aerial parts of Diplomorpha canescens; collected in Daman, Nepal

Devkota, Hari Prasad; Watanabe, Masato; Watanabe, Takashi; Yahara, Shoji; Chemical and Pharmaceutical Bulletin; vol. 60; nb. 4; (2012); p. 554 - 556, View in Reaxys

stems of Cordia rufescens; collected in Morro do Chapeu, Bahia State, Brazil

Do Vale, Ademir E.; David, Jorge M.; Dos Santos, Edlene O.; David, Juceni P.; E Silva, Lidercia C.R.C.; Bahia, Marcus V.; Brandão, Hugo N.; Phytochemistry; vol. 76; (2012); p. 158 - 161, View in Reaxys

stem of Hymenocardia wallichii; collected in Chaiyaphum Province, northeast Thailand, March 2010

Suthiwong, Jittra; Poopasit, Kitisak; Yenjai, Chavi; Journal of Asian Natural Products Research; vol. 14; nb. 5; (2012); p. 482 485, View in Reaxys

root tissue of Ehretia longiflora Champ. ex Benth. (Boraginaceae); collected at Mu-

Chien, Yu-Chieh; Lin, Chu-Hung; Chiang, Michael Y.; Chang, Hsun-Shuo; Liao, Chang-Hui; Chen, Ih-Sheng; Peng, ChienFang; Tsai, Ian-Lih; Phytochemistry; vol. 80; (2012); p. 50 - 57, View in Reaxys

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dan, Pingtung County, Taiwan branches of Uvaria ludida; collected in Kaloleni district, Kenya, 1995

Moriyasu, Masataka; Takeuchi, Sousuke; Ichimaru, Momoyo; Nakatani, Noriyshi; Nishiyama, Yumi; Kato, Atsushi; Mathenge, Simon G.; Juma, Francis D.; ChaloMutiso, Patrick B.; Journal of Natural Medicines; vol. 66; nb. 3; (2012); p. 453 - 458, View in Reaxys

leaves and stems of Ouratea ferruginea Engl. (Ochnaceae); collected in the campus of Embrapa in Belem, Para State, Brazil

Fidelis, Queli C.; Castro, Rosane N.; Guilhon, Giselle M.S.P.; Rodrigues, Silvane T.; De Salles, Cristiane M.C.; De Salles; De Carvalho, Mario G.; Molecules; vol. 17; nb. 7; (2012); p. 7989 - 8000, View in Reaxys

stems of Hibiscus taiwanensis; provided by Hercet Co. Ltd. (Kaohsiung, Taiwan)

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys

seed cake of Jatropha curcas L.; brought from Hainan Maoyuan Energy Co., Ltd.&#10;

Yao, Licheng; Han, Changri; Chen, Guangying; Song, Xiaoping; Chang, Yonghui; Zang, Wenxia; Fitoterapia; vol. 83; nb. 8; (2012); p. 1318 - 1321, View in Reaxys

roots of Panax japonicus C. A. Meyer var. major; purchased from Lijiang and Yongsheng, Yunnan Province, People's Republic of China, September - Decemver 2005

Chan, Hsiu-Hui; Hwang, Tsong-Long; Reddy, Mopur Vijaya Bhaskar; Li, Ding-Tzai; Qian, Keduo; Bastow, Kenneth F.; Lee, KuoHsiung; Wu, Tian-Shung; Journal of Natural Products; vol. 74; nb. 4; (2011); p. 796 - 802, View in Reaxys

stems and roots of Pisonia aculeata; collected from Mudan, Pingtung County, Taiwan

Wu, Ming-Chun; Peng, Chien-Fang; Chen, Ih-Sheng; Tsai, IanLih; Journal of Natural Products; vol. 74; nb. 5; (2011); p. 976 - 982, View in Reaxys

leaves of Cinnamomum subavenium Miq.; collected in Wulai Hsiang, Taipei County, Taiwan

Chen; Wang; Chemistry of Natural Compounds; vol. 47; nb. 2; (2011); p. 215 - 217, View in Reaxys

leaves of Neolitsea hiiranensis (Lauraceae); collected in Mudan, Pingtung County, Taiwan

Liou, Bi-Jiuan; Chang, Hsun-Shuo; Wang, Guei-Jane; Chiang, Michael Y.; Liao, Chang-Hui; Lin, Chu-Hung; Chen, Ih-Sheng; Phytochemistry; vol. 72; nb. 4-5; (2011); p. 415 - 422, View in Reaxys

wood of Platycarya strobilacea Sieb et Zucc; collected at Tsushima Island, Nagasaki, Japan

Maeda, Hajime; Kakoki, Narumi; Ayabe, Mami; Koga, Yuki; Oribe, Tomoko; Matsuo, Yosuke; Tanaka, Takashi; Kouno, Isao; Phytochemistry; vol. 72; nb. 8; (2011); p. 796 - 803, View in Reaxys

stem wood of Zanthoxylum nitidum; collected from Lai-I, Ping-

Chen, Jih-Jung; Lin, Yu-Hsien; Day, Shiow-Hwa; Hwang, TsongLong; Chen, Ih-Sheng; Food Chemistry; vol. 125; nb. 2; (2011); p. 282 - 287, View in Reaxys

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tung County, Taiwan seeds of Coix lachryma-jobi L. var ma-yuen Stapf

Chung, Cheng-Pei; Hsia, Shih-Min; Lee, Ming-Yi; Chen, HongJhang; Cheng, Faiwen; Chan, Lu-Chi; Kuo, Yueh-Hsiung; Lin, Yun-Lian; Chiang, Wenchang; Journal of Agricultural and Food Chemistry; vol. 59; nb. 11; (2011); p. 6025 - 6033, View in Reaxys

stems of Pisonia umbellifera Seem.; collected in Mudan, Pingtung county, Taiwan

Kuo, Hsiou-Ting; Peng, Chien-Fang; Huang, Hung-Yi; Lin, ChuHung; Chen, Ih-Sheng; Tsai, Ian-Lih; Planta Medica; vol. 77; nb. 7; (2011); p. 736 - 741, View in Reaxys

red yeast of with Monascus purpureus BCRC 38038

Cheng, Ming-Jen; Wu, Ming-Der; Chen, Ih-Sheng; Tseng, Min; Yuan, Gwo-Fang; Phytochemistry Letters; vol. 4; nb. 3; (2011); p. 372 - 376, View in Reaxys

twigs and bark of Laguncularia racemosa L Gaertn.; collected at Dongzhaigong, Hainan Island, PR China

Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

n-BuOH, 95percent EtOH extract of red yeast rice fermented with the Monascus pilosus BCRC 38093 (Eurotiaceae)

Wu, Ming-Der; Cheng, Ming-Jen; Yuan, Gwo-Fang; Yech, Yi-Jen; Chen, Ih-Sheng; Acta Chimica Slovenica; vol. 57; nb. 2; (2010); p. 305 - 309, View in Reaxys

wood of Magnolia grandiflora L. (Magnoliaceae)

Lee, Hak-Ju; Khan; Kang, Ha-Young; Choi, Don-Ha; Mi-Jin, Park; Hyun-Jung, Lee; Chemistry of Natural Compounds; vol. 46; nb. 2; (2010); p. 289 - 290, View in Reaxys

leaves of Mikania laevigata Shultz Bip. ex Baker; collected in Ribeirao Preto-SP, Brazil

supporting information

Ferreira, Fernanda Peres; De Oliveira, Dioneia Camilo Rodrigues; Tetrahedron Letters; vol. 51; nb. 52; (2010); p. 6856 - 6859, View in Reaxys

roots of Panax japonicus C. A. Meyer var. major; collected in Yunnan province, China

Chan, Hsiu-Hui; Sun, Han-Dong; Reddy, Mopur Vijaya Bhaskar; Wu, Tian-Shung; Phytochemistry; vol. 71; nb. 11-12; (2010); p. 1360 - 1364, View in Reaxys

whole plant of Fatoua pilosa Gaud. (Moraceae); collected at Ban-pin Mountain, Kaohsiung City, Taiwan, August 2006

Chiang, Chun-Ching; Cheng, Ming-Jen; Peng, Chien-Fang; Huang, Hung-Yi; Chen, Ih-Sheng; Chemistry and Biodiversity; vol. 7; nb. 7; (2010); p. 1728 - 1736, View in Reaxys

root wood of Magnolia kachirachirai (Kanehira & Yamamoto) Dandy; collected from Mudan, Pingtung County, Taiwan

Chang, Hsun-Shuo; Lee, Shiow-Ju; Yang, Cheng-Wei; Chen, IhSheng; Chemistry and Biodiversity; vol. 7; nb. 11; (2010); p. 2737 2747, View in Reaxys

dried steam bark of Magnolia officinalis L. (Magnoliae Cortex; Mag-

Shen, Chien-Chang; Ni, Ching-Li; Shen, Yuh-Chiang; Huang, YuLing; Kuo, Ching-Hsia; Wu, Tian-Shung; Chen, Chien-Chih; Journal of Natural Products; vol. 72; nb. 1; (2009); p. 168 - 171, View in Reaxys

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noliaceae) purchased from a market in Taipei, Taiwan stems of Diospyros maritima; collected in LinKo, Taiwan

Chang, Chi-I.; Chen, Chiy-Rong; Chiu, Hsi-Lin; Kuo, Chao-Lin; Kuo, Yueh-Hsiung; Molecules; vol. 14; nb. 12; (2009); p. 5281 5288, View in Reaxys

stem bark of Premna tomentosa (Verbenaceae)

Hymavathi; Suresh Babu; Naidu; Rama Krishna; Diwan, Prakash V.; Madhusudana Rao; Bioorganic and Medicinal Chemistry Letters; vol. 19; nb. 19; (2009); p. 5727 - 5731, View in Reaxys

leaves of Isatis tinctoria; collected at Agricultural Research Station of Thuringia, Dornburg, Germany

Mohn, Tobias; Plitzko, Inken; Hamburger, Matthias; Phytochemistry; vol. 70; nb. 7; (2009); p. 924 - 934, View in Reaxys

whole plant of Arabidopsis thaliana ecotype Columbia-0; collected at Miura Peninsula, Kanagawa, Japan, 2005, December

root of Picris strigosa M. Bieb.; collected in Garden of Medicinal Plants of Institute of Pharmacology, Polish Academy of Sciences, Krakow

Kisiel; Michalska; Nowak; Polish Journal of Chemistry; vol. 83; nb. 9; (2009); p. 1663 - 1667, View in Reaxys

leaves of Michelia compressa var. formosana; collected from Chiayi County, Taiwan

Wang; Lo; Lu; Yeh; Huang; Chen; Chemistry of Natural Compounds; vol. 45; nb. 6; (2009); p. 931 - 933, View in Reaxys

roots of Picris rhagadioloides (L.) Desf. (Asteraceae)

Michalska, Klaudia; Kisiel, Wanda; Molecules; vol. 13; nb. 2; (2008); p. 444 - 451, View in Reaxys

Populus euphratica

Luo, Jian-Rong; Jiang, Hong-En; Zhao, You-Xing; Zhou, Jun; Qian, Jin-Fu; Chemistry of Natural Compounds; vol. 44; nb. 1; (2008); p. 6 - 9, View in Reaxys

roots of Vepris uguenensis

Cheplogoi, Peter K.; Mulholland, Dulcie A.; Coombes, Philip H.; Randrianarivelojosia, Milijaona; Phytochemistry; vol. 69; nb. 6; (2008); p. 1384 - 1388, View in Reaxys

Aeschynanthus bracteatus, collected in Jinping County, Yunnan province, China

Li, Su-Mei; Yang, Xian-Wen; Shen, Yun-Heng; Feng, Lin; Wang, Yue-Hu; Zeng, Hua-Wu; Liu, Xiao-Hua; Tian, Jun-Mian; Shi, YaNa; Long, Chun-Lin; Zhang, Wei-Dong; Phytochemistry; vol. 69; nb. 11; (2008); p. 2200 - 2204, View in Reaxys

stem of Microtropis japonica (Fr. and Sav.) Hall. f. (Celastraceae); collected from Lanyu Island, Taitung County, Taiwan

Chen, Jih-Jung; Yang, Chang-Syun; Peng, Chien-Fang; Chen, IhSheng; Miaw, Chang-Ling; Journal of Natural Products; vol. 71; nb. 6; (2008); p. 1016 - 1021, View in Reaxys

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Fibraurea tinctoria; collected near Hanoi, Vietnam

Su, Chung-Ren; Chen, Yuh-Fung; Liou, Meei-Jen; Tsai, HueiYann; Chang, Wen-Shin; Wu, Tian-Shung; Bioorganic and Medicinal Chemistry; vol. 16; nb. 21; (2008); p. 9603 - 9609, View in Reaxys

root wood of Zanthoxylum wutaiense Chen (Rutaceae); collected from Wutai, Pingtung County, Taiwan

Huang, Hung-Yi; Ishikawa, Tsutomu; Peng, Chien-Fang; Tsai, Ian-Lih; Chen, Ih-Sheng; Journal of Natural Products; vol. 71; nb. 7; (2008); p. 1146 - 1151, View in Reaxys

Euphorbia lagascae cultivated in Cova da Beira, Coimbra, Portugal

Duarte, Noelia; Ferreira, Maria-Jose U.; Organic Letters; vol. 9; nb. 3; (2007); p. 489 - 492, View in Reaxys

leaves and twigs of Urophylluma chinensis Merret Chun collected from Guizhou Province of China, in November 2004

Guo, Hui; Cai, Xiaohua; Qian, Junqing; Journal of Chemical Research; nb. 1; (2007); p. 24 - 25, View in Reaxys

Tarenna attenuata (Rubiaceae), whole plant (Xishuangbanna, Yunnan Province, People's Republic of China)

Yang, Xian-Wen; Wang, Jun-Song; Wang, Yue-Hu; Xiao, Hai-Tao; Hu, Xu-Jia; Mu, Shu-Zhen; Yan-Lin, Ma.; Lin, Hua; He, HongPing; Li, Ng; Hao, Xiao-Jiang; Planta Medica; vol. 73; nb. 5; (2007); p. 496 - 498, View in Reaxys

dry roots of Rhus javanica var. roxburghiana (Anacardiaceae) collected from the suburb of Taipei, Taiwan in 1998

Ouyang, Ming-An; Wein, Yung-Shung; Su, Ren-Kuan; Kuo, YuehHsiung; Chemical and Pharmaceutical Bulletin; vol. 55; nb. 5; (2007); p. 804 - 807, View in Reaxys

root wood of Zanthoxylum integrifoliolum (Merr.) (Rutaceae) collected on Lanyu Island, Taitung County, Taiwan, July of 2002

Cheng, Ming-Jen; Lin, Chuan-Fang; Wang, Chyi-Jia; Tsai, IanLih; Chen, Ih-Sheng; Journal of the Chinese Chemical Society; vol. 54; nb. 3; (2007); p. 779 - 783, View in Reaxys

stems of Cinnamomum subavenium Miq. (Lauraceae) collected from Wulai Hsiang, Taipei County, Taiwan

Chen, Chung-Yi; Chen, Ching-Hsein; Wong, Chung-Hang; Liu, Yi-Wen; Lin, Yu-Shan; Wang, Yau-Der; Hsui, Yen-Ray; Journal of Natural Products; vol. 70; nb. 1; (2007); p. 103 - 106, View in Reaxys

stem wood of Zanthoxylum integrifoliolum (Merr.) collected from Lanyu Island, Taitung County, Taiwan

Chen, Jih-Jung; Chen, Po-Hou; Liao, Chang-Hui; Huang, Shi-Yu; Chen, Ih-Sheng; Journal of Natural Products; vol. 70; nb. 9; (2007); p. 1444 - 1448, View in Reaxys

Viscum coloratum (Loranthaceae) (Chuang Song Zong company, Pingtung, Taiwan)

Leu, Yann-Lii; Hwang, Tsong-Long; Chung, Yu-Ming; Hong, PaoYun; Chemical and Pharmaceutical Bulletin; vol. 54; nb. 7; (2006); p. 1063 - 1066, View in Reaxys

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Garcinia linii C.E. Chang (Guttiferae), roots (Lanyu Island, Taiwan)

Chen, Jih-Jung; Peng, Chien-Fang; Huang, Hung-Yi; Chen, IhSheng; Planta Medica; vol. 72; nb. 5; (2006); p. 473 - 477, View in Reaxys

leaves of Cinnamomum kotoense Kanehira and Sasaki (Lauraceae) collected from Fooyin University, Kaohsiung County, Taiwan

Chen, Ching-Hsein; Lo, Wen-Li; Liu, Ya-Chen; Chen, Chung-Yi; Journal of Natural Products; vol. 69; nb. 6; (2006); p. 927 - 933, View in Reaxys

the fresh roots of Taraxacum formosanum (Compositae), Taiwan

Leu, Yann-Lii; Wang, Yu-Li; Huang, Shih-Chin; Shi, Li-Shian; Chemical and Pharmaceutical Bulletin; vol. 53; nb. 7; (2005); p. 853 855, View in Reaxys

the roots of Rhus javanica L. var. roxburghiana collected at Kaohsiung, Taiwan, in June, 2000

Lee, Tzong-Huei; Chiou, Jong-Liang; Lee, Ching-Kuo; Kuo, Yueh-Hsiung; Journal of the Chinese Chemical Society; vol. 52; nb. 4; (2005); p. 833 - 841, View in Reaxys

Melicope semecarpifolia (Merr.) T. Hartley, root wood (Lai-I, Pingtung County, Taiwan)

Chou, Hsueh-Chun; Chen, Jih-Jung; Duh, Chang-Yih; Huang, Tur-Fu; Chen, Ih-Sheng; Planta Medica; vol. 71; nb. 11; (2005); p. 1078 - 1081, View in Reaxys

Goldfussia psilostachys (C. B. Clarke ex W. W. Smith) Brem. (Acanthaceae), whole plants (Xishuangbanna, Yunnan Province, China)

Luo, Yinggang; Zhou, Min; Qi, Huayi; Li, Bogang; Zhang, Guolin; Planta Medica; vol. 71; nb. 11; (2005); p. 1081 - 1084, View in Reaxys

stems of Pilocarpus grandiflorus collected in Pocos D'antas, municipio de Murici, Alagoas state, Brazil

aerial parts of Boronella koniambiensis collected in Koniambo Mountains, New Caledonia

Grougnet, Raphael; Magiatis, Prokopios; Fokialakis, Nikolas; Mitaku, Sofia; Skaltsounis, Alexios-Leandros; Tillequin, Francois; Sevenet, Thierry; Litaudon, Marc; Journal of Natural Products; vol. 68; nb. 7; (2005); p. 1083 - 1086, View in Reaxys

stem wood of Cinnamomum kotoense Kanehira et Sasaki (Lauraceae) purchased from Wandan, Pingtung County, Taiwan

Chen, Fu-Chi; Peng, Chien-Fang; Tsai, Ian-Lih; Chen, Ih-Sheng; Journal of Natural Products; vol. 68; nb. 9; (2005); p. 1318 - 1323, View in Reaxys

stems of Ilex litseaefolia Hu et Tang (Aquifoliaceae) collected from Gaoqiao Village, Zemulong Countyside, Yan-

Zhang, Ai-Lian; Ye, Qi; Li, Bo-Gang; Qi, Hua-Yi; Zhang, Guo-Lin; Journal of Natural Products; vol. 68; nb. 10; (2005); p. 1531 - 1535, View in Reaxys

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bian County in Sichuan Province of the People's Republic of China stems of Hibiscus taiwanensis Hu (Malvaceae) (Tainan Hsien, Taiwan, Republic of China, February 2001)

Wu, Pei-Lin; Wu, Tian-Shung; He, Cai-Xia; Su, Chia-Hao; Lee, Kuo-Hsiung; Chemical and Pharmaceutical Bulletin; vol. 53; nb. 1; (2005); p. 56 - 59, View in Reaxys

roots of Eurycoma longifolia Jack collected in Malaysia

Kuo, Ping-Chung; Damu, Amooru G.; Lee, Kuo-Hsiung; Wu, Tian-Shung; Bioorganic and Medicinal Chemistry; vol. 12; nb. 3; (2004); p. 537 - 544, View in Reaxys

whole plant of Cacalia deltophylla (Maxim.) Mattf. (Compositae) collected in Forestry Center ShuangCha in Luqu county, Gansu Province, People's Republic of China

Wang, Ying; Yang, Min; Yuan, Cheng-Shan; Han, Yi-Feng; Jia, Zhong-Jian; Pharmazie; vol. 58; nb. 8; (2003); p. 596 - 598, View in Reaxys

the root bark of Formosan Zanthoxylum ailanthoides, collected at Lai-I, Pingtung County, Taiwan, in December 1999

Cheng, Ming-Jen; Tsai, Ian-Lih; Chen, Ih-Sheng; Journal of the Chinese Chemical Society; vol. 50; nb. 6; (2003); p. 1241 - 1246, View in Reaxys

stems of Casearia membranacea Hance (Flacourtiaceae) collected in Pingtung County, Taiwan

Chang, Keng-Chia; Duh, Chang-Yih; Chen, Ih-Sheng; Tsai, IanLih; Planta Medica; vol. 69; nb. 7; (2003); p. 667 - 672, View in Reaxys

core of stems of kenaf (Hibiscus cannabinus, variety Salvador)

Seca, Ana M.L.; Silva, Artur M.S.; Silvestre, Armando J.D.; Cavaleiro, Jose A.S.; Domingues, Fernando M.J.; Pascoal-Neto, Carlos; Phytochemistry; vol. 56; nb. 7; (2001); p. 759 - 767, View in Reaxys

stems of Eugenia sandwicensis

Gu, Jian-Qiao; Park, Eun Jung; Luyengi, Lumonadio; Hawthorne, Michael E.; Mehta, Rajendra G.; Farnsworth, Norman R.; Pezzuto, John M.; Kinghorn; Phytochemistry; vol. 58; nb. 1; (2001); p. 121 - 127, View in Reaxys

stem wood of Machilus obovatifolia Kanehira et Sasaki (Lauraceae)

Tsai; Chen; Duh; Planta Medica; vol. 67; nb. 6; (2001); p. 559 - 561, View in Reaxys

roots of Hydrangea chinensis

Patnam; Chang; Chen; Kuo; Lee; Wu; Journal of Natural Products; vol. 64; nb. 7; (2001); p. 948 - 949, View in Reaxys

root of Gynura elliptica, Lanyu Island, Taitung County, Taiwan

Lin, Wei-Yu; Teng, Che-Ming; Tsai, Ian-Lih; Chen, Ih-Sheng; Phytochemistry; vol. 53; nb. 8; (2000); p. 833 - 836, View in Reaxys

bark of Brosimum acutifolium, Portel county, State of Para, Brazil

Torres, Sergio Luiz; Arruda, Mara Silvia P.; Arruda, Alberto C.; Mueller, Adolfo H.; Silva, Sebastiao C.; Phytochemistry; vol. 53; nb. 8; (2000); p. 1047 - 1050, View in Reaxys

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leaves and twings of Manglietiastrum sinicum, Magnoliaceae, collected in Wenshan district, southeastern region of Yunnan Province, China

Wang; Hong; Li; Zhou; Hao; Planta Medica; vol. 66; nb. 6; (2000); p. 511 - 515, View in Reaxys

roots of Boronia pinnata

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 - 1348, View in Reaxys

heartwood of Eucalyptus citriodora collected on the campus of National Taiwan University

Lee, Ching-Kuo; Chang, Ming-Huey; Journal of the Chinese Chemical Society; vol. 47; nb. 3; (2000); p. 555 - 560, View in Reaxys

roots of Gymnosporia trigyna

Deng; Newman; Hecht; Journal of Natural Products; vol. 63; nb. 9; (2000); p. 1269 - 1272, View in Reaxys

aerial parts of the flowering plant Centaurea nicolai

Vajs, Vlatka; Todorovic, Nina; Ristic, Marina; Tesevic, Vele; Todorovic, Borislav; Janackovic, Pedja; Marin, Petar; Milosavljevic, Slobodan; Phytochemistry; vol. 52; nb. 3; (1999); p. 383 - 386, View in Reaxys

Annona cherimola Mill. (Annonaceae)

Chen, Chung-Yi; Chang, Fang-Rong; Teng, Che-Ming; Wu, YangChang; Journal of the Chinese Chemical Society; vol. 46; nb. 1; (1999); p. 77 - 86, View in Reaxys

adult and intermediate leaf sheaths and adult blades of Posidonia oceanica

Agostini, Sylvia; Desjobert, Jean-Marie; Pergent, Gerard; Phytochemistry; vol. 48; nb. 4; (1998); p. 611 - 617, View in Reaxys

isolation from the dissolved organic matter (DOM) extracted from lake water (the Lake Savojaervi, Finland, 1994) by different methods: non-ionic sorbing solid: XAD-8; weakly basic cation exchanger: IRA-67; DEAE cellulose

Hautala, Kimmo; Peuravuori, Juhani; Pihlaja, Kalevi; Chemosphere; vol. 35; nb. 4; (1997); p. 809 - 817, View in Reaxys

Lithospermum erythrorhizon Sieb. et Zucc. M18 cells

Yazaki, Kazufumi; Fukui, Hiroshi; Nishikawa, Yumiko; Tabata, Mamoru; Bioscience, Biotechnology and Biochemistry; vol. 61; nb. 10; (1997); p. 1674 - 1678, View in Reaxys

Ilex rotunda

Wen Dong-Xu; Chen Zhong-Liang; Phytochemistry; vol. 41; nb. 2; (1996); p. 657 - 659, View in Reaxys

whole plants of Coriandrum sativum L.

Taniguchi, Masahiko; Yanai, Masayuki; Xiao, Yong Qing; Kido, Tadashi; Baba, Kimiye; Phytochemistry; vol. 42; nb. 3; (1996); p. 843 - 846, View in Reaxys

stem bark of Citrus macroptera Montr.

Gaillard; Muyard; Bevalot; Regnier; Vaquette; Annales pharmaceutiques francaises; vol. 53; nb. 2; (1995); p. 75 - 78, View in Reaxys

stems of Annona montana Macf. (Annonaceae), Chie Shan, Kaohsiung, Hsien, Taiwan

Wu; Chang; Ko; Teng; Planta medica; vol. 61; nb. 2; (1995); p. 146 - 149, View in Reaxys

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Aralia bipinnata

Hsiao, Jen-Jian; Chiang, Hung-Chen; Phytochemistry (Elsevier); vol. 39; nb. 4; (1995); p. 899 - 902, View in Reaxys

heartwood of Tetradium glabrifolium

Wu. Tian-Shung; Yeh, Jyh-Her; Wu, Pei-Lin; Phytochemistry (Elsevier); vol. 40; nb. 1; (1995); p. 121 - 124, View in Reaxys

Rhizophora apiculata (heartwood)

Kokpol, Udom; Chavasiri, Warinthorn; Chittawong, Vallapa; Bruce, Marc; Cunningham, G. N.; et al.; Phytochemistry (Elsevier); vol. 33; nb. 5; (1993); p. 1129 - 1132, View in Reaxys

Mikania shusunensis Holmes and McDaniel

Gutierrez, Alicia B.; Herz, Werner; Phytochemistry (Elsevier); vol. 27; nb. 12; (1988); p. 3871 - 3874, View in Reaxys

Feronia limonia

Reisch, J.; Hussain, R. A.; Adesina, S. K.; Pharmazie; vol. 40; nb. 7; (1985); p. 503 - 504, View in Reaxys

Phyllostachys nigra MUNRO var. henonis STAPF.

Nikaido; Sung; Ohmoto; Sankawa; Chemical and Pharmaceutical Bulletin; vol. 32; nb. 2; (1984); p. 578 - 584, View in Reaxys

graminaceous cell walls of Zea mays, Hordeum vulgare and Triticum aestivum

Hartley, Roy D.; Keene, Annie S.; Phytochemistry (Elsevier); vol. 23; nb. 6; (1984); p. 1305 - 1308, View in Reaxys

Ambrosia cumanensis

Verbesina sublobata

Herz,W.; Kumar,N.; Phytochemistry (Elsevier); vol. 20; (1980); p. 247, View in Reaxys

seed balls of red beet (Beta vulgaris L. var. rubra)

Chiji, Hideyuki; Tanaka, Shigenori; Izawa, Masao; Agricultural and Biological Chemistry; vol. 44; nb. 1; (1980); p. 205 - 208, View in Reaxys

Licaria Puchurymajor.

Da Silva et al.; Phytochemistry (Elsevier); vol. 12; (1973); p. 471,472, View in Reaxys

Betula verrucosa

Lundquist,K.; Acta Chemica Scandinavica (1947-1973); vol. 27; (1973); p. 2597 - 2606, View in Reaxys

Geroestete Gerste

Shimizu et al.; Agricultural and Biological Chemistry; vol. 34; (1970); p. 437,439, View in Reaxys

Birkenholz, 1.) Wasserdampf-hydrolysat, 2.) Nitrobenzolox.

Klemola; Suomen Kemistilehti B; vol. 41; nb. 3; (1968); p. 83, View in Reaxys

Buchenholz, Roggenstroh od. Bambus, 1) wss. SO2, zuletzt b. 130grad, 2)Δ m. KOH auf 140grad

Kratzl; Claus; Monatshefte fuer Chemie; vol. 93; (1962); p. 219,225, 229, View in Reaxys

Quantum Chemical Calculations (2) Calculated Prop- Method (Quantum References erties Chemical Calculations) Ionization potential, orbital energy; Proton affinity; IR bands, intensities, transition moments; Atom distances, angles

Ab initio calcns. (LCAO, GO SCF, DIM, SAMO, X-à, Hartree-Fock)

Yancheva; Velcheva; Glavcheva; Stamboliyska; Smelcerovic; Journal of Molecular Structure; vol. 1108; (2016); p. 552 - 559, View in Reaxys

Dipole moment, dipole moment

Ab initio calcns. (LCAO, GO SCF,

Jenita, M. Jude; Mohandass; Rajendiran; Journal of Fluorescence; vol. 24; nb. 3; (2014); p. 695 - 707, View in Reaxys

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derivative; Molec- DIM, SAMO, X-à, ular orbitals; Elec- Hartree-Fock) tronic energy levels Medchem (200) 1 of 200

Substance Effect

Anti-Tuberculosis

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Target : Mycobacterium tuberculosis 90-221387Bioassay : OADC: oleic acid-albumin-dextrose-catalase; ethambutol used as positive control (MIC = 6.2 mg/l) bacteria incubated in title comp.-containing Middlebrook 7H10 agar supplemented with OADC at 35 deg C with 10 percent CO2 for 2 weeks

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

0.800000 mg/L

Measurement Parameter

MIC

Unit

mg/L

Quantitative value

100

Measurement pX

3.26

Chen, Jih-Jung; Peng, Chien-Fang; Huang, Hung-Yi; Chen, Ih-Sheng; Planta Medica; vol. 72; nb. 5; (2006); p. 473 - 477, View in Reaxys 2 of 200

Substance Effect

Cytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Bioassay : positive control: mithramycin (ED50: 0.58 μg/ml) cells treated with title comp.; cytotoxicity determined

Biological Species/NCBI Mus musculus ID Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

ED50

Unit

mg/L

Quantitative value

Measurement pX

3.56

Chang, Keng-Chia; Duh, Chang-Yih; Chen, Ih-Sheng; Tsai, Ian-Lih; Planta Medica; vol. 69; nb. 7; (2003); p. 667 - 672, View in Reaxys 3 of 200

Substance Effect

Cytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Bioassay : positive control: mithramycin (ED50: 0.076 μg/ml) cells treated with title comp.; cytotoxicity determined

Biological Species/NCBI Human ID Cells/Cell Lines

cells

Substance RN

784514View in Reaxys

Substance Name

65585

61/130

2017-10-08 12:35:19

Measurement Parameter

ED50

Unit

mg/L

Quantitative value

Measurement pX

3.56

Chang, Keng-Chia; Duh, Chang-Yih; Chen, Ih-Sheng; Tsai, Ian-Lih; Planta Medica; vol. 69; nb. 7; (2003); p. 667 - 672, View in Reaxys 4 of 200

Substance Effect

Cytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Bioassay : positive control: mithramycin (ED50: 0.073 μg/ml) cells treated with title comp.; cytotoxicity determined

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

ED50

Unit

mg/L

Quantitative value

Measurement pX

3.56

Chang, Keng-Chia; Duh, Chang-Yih; Chen, Ih-Sheng; Tsai, Ian-Lih; Planta Medica; vol. 69; nb. 7; (2003); p. 667 - 672, View in Reaxys 5 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

bud exudate of Populus lasiocarpa

Measurement Parameter

Qualitative

Greenaway, W.; Scaysbrook, T.; Whatley, F. R.; Phytochemistry (Elsevier); vol. 27; nb. 11; (1988); p. 3513 - 3516, View in Reaxys 6 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : IL-1 induced PGE2 expression; effect onTarget : skin fibroblasts of humanBioassay : EXAMPLE 6; In vitro experiments were conducted to demonstrate the activity of a series of aromatic aldehydes as agents in topically-administered pharmaceuticals and cosmetics. The compounds tested and the measured results are tabulated in Fig. 6 and shown graphically in Figs. 8-11. These data include

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

title compound (100 μmol/l) inhibited IL-1 induced PGE2 expression by 55% compared to diluent control; diagram given

Measurement Parameter

Qualitative

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 7 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

62/130

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Bioassay Details

Effect : tetradecanoyl phorbol acetate (TPA) induced IL-1 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 8 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : tetradecanoyl phorbol acetate (TPA) induced IL-6 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 9 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : tetradecanoyl phorbol acetate (TPA) induced IL-8 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 10 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : tetradecanoyl phorbol acetate (TPA) induced MMP-1 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys

63/130

2017-10-08 12:35:19

11 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : tetradecanoyl phorbol acetate (TPA) induced PGE2 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 12 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : tetradecanoyl phorbol acetate (TPA) induced TNF-α expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 13 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced IL-1 expression; effect onTarget : skin fibroblasts of humanBioassay : EXAMPLE 6; In vitro experiments were conducted to demonstrate the activity of a series of aromatic aldehydes as agents in topically-administered pharmaceuticals and cosmetics. The compounds tested and the measured results are tabulated in Fig. 6 and shown graphically in Figs. 8-11. These data include

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 14 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced IL-1 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

64/130

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Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 15 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced IL-6 expression; effect onTarget : skin fibroblasts of humanBioassay : EXAMPLE 6; In vitro experiments were conducted to demonstrate the activity of a series of aromatic aldehydes as agents in topically-administered pharmaceuticals and cosmetics. The compounds tested and the measured results are tabulated in Fig. 6 and shown graphically in Figs. 8-11. These data include

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 16 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced IL-6 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 17 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced IL-8 expression; effect onTarget : skin fibroblasts of humanBioassay : EXAMPLE 6; In vitro experiments were conducted to demonstrate the activity of a series of aromatic aldehydes as agents in topically-administered pharmaceuticals and cosmetics. The compounds tested and the measured results are tabulated in Fig. 6 and shown graphically in Figs. 8-11. These data include

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 18 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced IL-8 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

65/130

2017-10-08 12:35:19

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 19 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced MMP-1 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 20 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced PGE2 expression; effect onTarget : skin fibroblasts of humanBioassay : EXAMPLE 6; In vitro experiments were conducted to demonstrate the activity of a series of aromatic aldehydes as agents in topically-administered pharmaceuticals and cosmetics. The compounds tested and the measured results are tabulated in Fig. 6 and shown graphically in Figs. 8-11. These data include

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 21 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced PGE2 expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 22 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : UV-light induced TNF-α expression; effect onTarget : skin keratinocytes of humanBioassay : EXAMPLE 7; Similar in vitro studies as those described in Example 6 were run using human skin keratiiiocytes. The experimental set up was the same as described for Example 6. The products assayed by ELISA for the presence of PGE-2, IL-I, IL-6, IL-8, MMP-I or TNF-O. in the culture medium.For the cells

66/130

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Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys 23 of 200

Target Mutant/Chimera Details

Glucagon:Wild

Target Subunit Proteins

Glucagon

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : IL-1 induced IL-6 expression; effect onBioassay : EXAMPLE 6; In vitro experiments were conducted to demonstrate the activity of a series of aromatic aldehydes as agents in topically-administered pharmaceuticals and cosmetics. The compounds tested and the measured results are tabulated in Fig. 6 and shown graphically in Figs. 8-11. These data include

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

title compound (100 μmol/l) inhibited IL-1 induced IL-6 expression by 48% compared to diluent control; diagram given

Measurement Parameter

Qualitative

Target, Subunit, Species Glucagon Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys

24 of 200

Target Subunit Synonyms

gcg (glucagon); glucagon; uncleaved glucagon

Target Mutant/Chimera Details

Interleukin-8:Wild

Target Subunit Proteins

Interleukin-8

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : IL-1 induced IL-8 expression; effect onBioassay : EXAMPLE 6; In vitro experiments were conducted to demonstrate the activity of a series of aromatic aldehydes as agents in topically-administered pharmaceuticals and cosmetics. The compounds tested and the measured results are tabulated in Fig. 6 and shown graphically in Figs. 8-11. These data include

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

title compound (100 μmol/l) inhibited IL-1 induced IL-8 expression by 38% compared to diluent control; diagram given

Measurement Parameter

Qualitative

Target, Subunit, Species Interleukin-8 Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys Target Subunit Synonyms

9e3; alveolar macrophage chemotactic factor i; amcf-i; c-x-c motif chemokine 8; cef-4; cef4; chemokine (c-x-c motif) ligand 8; cxcl8; embryo fibroblast protein 1; emf-1; emf1 (interleukin-8); emoctakin; gcp-1; granulocyte chemotactic protein 1; il-8; il8; interleukin-8; mdncf; monap; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; nap-1; neutrophil attractant protein 1; neutrophil attractant/activa-

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tion protein 1; neutrophil-activating protein 1; permeability factor 1; pf1; protein 3-10c; rpf1; t-cell chemotactic factor; uncleaved interleukin-8 25 of 200

Target Mutant/Chimera Details

Interstitial collagenase:Wild

Target Subunit Proteins

Interstitial collagenase

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : IL-1 induced MMP-1 expression; effect onBioassay : EXAMPLE 6; In vitro experiments were conducted to demonstrate the activity of a series of aromatic aldehydes as agents in topically-administered pharmaceuticals and cosmetics. The compounds tested and the measured results are tabulated in Fig. 6 and shown graphically in Figs. 8-11. These data include

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Target, Subunit, Species Interstitial collagenase Patent; BIOFORM MEDICAL, INC.; WO2007/2447; (2007); (A2) English, View in Reaxys

26 of 200

Target Subunit Synonyms

clg; fibroblast collagenase; interstitial collagenase; interstitial collagenase a; matrix metalloproteinase-1; matrix metalloproteinase-1a; mcol-a; mcola; mmp-1; mmp-1a; mmp1 (interstitial collagenase); mmp1a; myocardial collagenase; tc1 (interstitial collagenase)

Substance Effect

Anti-Tuberculosis

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Effect : growthSpecies : Mycobacterium tuberculosis H37Rv

Biological Species/NCBI Mycobacterium tuberculosis ID Substance RN

784514View in Reaxys

Substance Name

Substance Dose

0.800000 µg/mL

Measurement Parameter

MIC

Unit

µM

Qualitative value

Quantitative value

400

Measurement pX

Chen, Jih-Jung; Yang, Chang-Syun; Peng, Chien-Fang; Chen, Ih-Sheng; Miaw, Chang-Ling; Journal of Natural Products; vol. 71; nb. 6; (2008); p. 1016 - 1021, View in Reaxys 27 of 200

Substance Effect

Antiapoptotic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Apoptosis

Bioassay Details

Target : fibroblastoid HSF cells of humanBioassay : control: without title comp. cells incub. with title comp. for 2 h; irradiated with 60-cobalt γ-ray (8 Gy); after 1 h post-irradiation, cells fixed; stained with fluorescein diacetate and Hoechst 33258; apoptosis determined by fluorescent microscopy

Substance RN

784514View in Reaxys

Substance Name

65585

68/130

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Qualitative Results

title comp. decreased the radiation-induced apoptosis

Measurement Parameter

Qualitative

Zheng, Hong; Chen, Zhi-Wu; Wang, Lin; Wang, Si-Ying; Yan, Yu-Qian; Wu, Ke; Xu, Qin-Zhi; Zhang, Shi-Meng; Zhou, Ping-Kun; European Journal of Pharmaceutical Sciences; vol. 33; nb. 1; (2008); p. 52 - 59, View in Reaxys 28 of 200

Substance Effect

Antiapoptotic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Apoptosis

Bioassay Details

Target : lymphoblastoid AHH-1 cells of humanBioassay : control: without title comp. cells incub. with title comp. for 2 h; irradiated with 60-cobalt γ-ray (8 Gy); after 1 h post-irradiation, cells fixed; incub. for 20 min at 37 deg C; stained with propidium iodide; cell-cycle distribution and sub-G1 population detd. by flow cytometry

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

5 µM

Qualitative Results

title comp. (10 and 40 μM) signif. decreased the occurrence of 8 Gy irradiation-induced apoptosis; fig.

Measurement Parameter

Qualitative

Substance Effect

Antiapoptotic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Apoptosis

Bioassay Details

Target : lymphoblastoid AHH-1 cells of humanBioassay : control: without title comp. cells incub. with title comp. for 2 h; irradiated with 60-cobalt γ-ray (8 Gy); after 1 h post-irradiation, cells fixed; stained with fluorescein diacetate and Hoechst 33258; apoptosis determined by fluorescent microscopy

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

title comp. decreased the radiation-induced apoptosis

Measurement Parameter

Qualitative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : protein expression; increase ofTarget : lymphoblastoid AHH-1 cells of humanBioassay : control: without title comp.; DNA-PKcs: DNA-dependent protein kinase catalytic subunit; phospho-Akt: phosphorylated Akt; phospho-GSK3β: phosphorylated glycogen synthase kinase-3 β cells incubated with title comp. for 8 h; irradiated with 60-cobalt γ-ray (4 Gy); after 6 h post-irradiation incubation, cells harvested; proteins separated; protein levels of DNA-PKcs, Ku70, phospho-Akt and -GSK3β detd. by immuno-hybridization assay

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

5 µM

Qualitative Results

title comp. (10 μM) resulted in a higher level of DNA-PKcs than control; title comp. increased levels of phospho-Akt and phospho-GSK3β; title comp. did not affect Ku70 protein levels; fig.

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Measurement Parameter

Qualitative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : protein phosphorylation; decrease ofTarget : lymphoblastoid AHH-1 cells of humanBioassay : control: without title comp.; γH2AX: phosphorylated histone protein H2AX cells incubated with title comp. for 8 h; irradiated with 60-cobalt γ-ray (2 Gy); γH2AX levels determined by immuno-hybridization assay

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

10 µM

Qualitative Results

title comp. exhibited much lower level of 2 Gy irradiation-induced γH2AX than control; fig.

Measurement Parameter

Qualitative

Substance Effect

Antioxidant

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Target : xanthine and xanthine oxidaseBioassay : control: without title comp.; reference compound: vanillin enzymes incubated with title comp. in sodium/potassium phosphatebuffered saline, pH 7.4; hydroxyl radical generated during the reaction mixture of Fe(2+)/ H2O2; samples placed in ESR cavity; ESR spectra recorded using ESR spectrometer

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

20 µM

Qualitative Results

title comp. inhibited ESR signal of hydroxyl free radical by 57% compared to reference compound; inhibition of ESR signal of superoxide radical by title comp. was also more potent than reference compound; fig.

Measurement Parameter

Qualitative

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Target : lymphoblastoid AHH-1 cells of humanBioassay : control: without title comp. cells incubated with title comp. for 2 h; irradiated with 60-cobalt γ-ray (4 Gy) at room temp.; after 72 h of post-irradiation, MTT added; incubated for 4 h at 37 deg C; absorbance was read in ELISA plate reader at 492 nm

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

5 µM

Qualitative Results

title comp. signif. attenuated the inhibition of proliferation; fig.

Measurement Parameter

Qualitative

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34 of 200

Substance Effect

Cytoprotective

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Target : fibroblastoid HSF cells of humanBioassay : control: without title comp. cells incubated with title comp. for 24 h; irradiated with 60-cobalt γ-ray (4 Gy); cells trypsinized; fixed; stained with Giemsa solution; cell numbers counted

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

1 µM

Qualitative Results

title comp. attenuated the growth inhibition of cells; title comp. increased the resistance of cells to ionizing radiation; fig.

Measurement Parameter

Qualitative

Substance Effect

Genoprotective

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Target : lymphoblastoid AHH-1 cells of humanBioassay : control: without title comp.; DSBs: DNA double-strand breaks; SSBs: DNA single-strand breaks cells incubated with title comp.; irradiated with 60-cobalt γ-ray (8 Gy); incubated for 1 h at 37 deg C; DNA separated and subjected to electrophoresis; DNA damage determined by Comet assay

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

5 µM

Qualitative Results

title comp. signif. decreased the initial production of DSBs as well as the residual level of DSBs at 1 h post-irradiation; title comp. decreased the production of radiation-induced SSBs; fig.

Measurement Parameter

Qualitative

Substance Effect

Genoprotective

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Target : pGEM-T/XRCC1 plasmid DNABioassay : AGE: agarose gel electrophoresis; control: without title comp.; reference compound: vanillin plasmid DNA incubated with title comp. in Tris-HCl, pH 7.2; subjected to 60-cobalt γ-ray (10-50 Gy) at room temp.; DNA separated by AGE; bands of supercoiled DNA and open circular DNA visualized with ethidium bromide fluorescent staining under UV light

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

10 µM

Qualitative Results

title comp. signif. reduced radiation-induced plasmid DNA breaks; fig.

Measurement Parameter

Qualitative

Substance Effect

Cytotoxic

Bioassay Category

Toxicity/Safety Pharmacology

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Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Effect : cell growth

Biological Species/NCBI Human ID Cells/Cell Lines

HCT-8

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

Qualitative

Qualitative value

Chan, Hsiu-Hui; Hwang, Tsong-Long; Reddy, Mopur Vijaya Bhaskar; Li, Ding-Tzai; Qian, Keduo; Bastow, Kenneth F.; Lee, Kuo-Hsiung; Wu, Tian-Shung; Journal of Natural Products; vol. 74; nb. 4; (2011); p. 796 - 802, View in Reaxys 38 of 200

Substance Effect

Cytotoxic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Effect : cell growth

Biological Species/NCBI Human ID Cells/Cell Lines

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Cytotoxic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Effect : cell growth

Biological Species/NCBI Human ID Cells/Cell Lines

A 549

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Cytotoxic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Effect : cell growth

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Biological Species/NCBI Human ID Cells/Cell Lines

DU 145

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Cytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Patnam; Chang; Chen; Kuo; Lee; Wu; Journal of Natural Products; vol. 64; nb. 7; (2001); p. 948 - 949, View in Reaxys 42 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

no activity in substrate specificity test of methanol-induced dehydrogenase and vanillyl alcohol-induced dehydrogenase of Rhodopseudomonas acidophila 10050

Measurement Parameter

Qualitative

Yamanaka, Kei; Minoshima, Ryoichi; Agricultural and Biological Chemistry; vol. 48; nb. 1; (1984); p. 171 - 180, View in Reaxys 43 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

activity in the test on utilization as carbon source by Rhodopseudomonas acidophila M402 under anaerobic-light conditions, no activity under aerobic-dark conditions at 0.1percent

Measurement Parameter

Qualitative

Yamanaka, Kei; Moriyama, Masami; Minoshima, Ryoichi; Tsuyuki, Yasutaka; Agricultural and Biological Chemistry; vol. 47; nb. 6; (1983); p. 1257 - 1268, View in Reaxys 44 of 200

Substance Effect

Hepatoprotective

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Bioassay : silybin with 19.6-21.2 percent relative protection used as positive control; GPT: glutamic pyruvic transaminase in vitro; effect on CCl4-induced hepatotoxicity assayed;

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5E5 cells/ml; incubated with 5 mmol/l CCl4/ethanol in the presence of title comp. in incubation medium; GPT activity measured Biological Species/NCBI Rattus norvegicus ID Cells/Cell Lines

liver cell

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

1 µM

Measurement Parameter

Qualitative

Qualitative value

Eun, Ju Lee; So, Ra Kim; Kim, Jinwoong; Young, Choong Kim; Planta Medica; vol. 68; nb. 5; (2002); p. 407 411, View in Reaxys 45 of 200

Substance Effect

Phytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : elongation

Biological Species/NCBI Bidens pilosa ID Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

0.100000 mg/mL

Measurement Parameter

% Inhibition

Unit

Quantitative value

76.1

Measurement pX

3.76

Tran, Dang Xuan; Tsuneaki, Toyama; Masakazu, Fukuta; Tran, Dang Khanh; Shinkichi, Tawata; Journal of Agricultural and Food Chemistry; vol. 57; nb. 20; (2009); p. 9448 - 9453, View in Reaxys 46 of 200

Substance Effect

Phytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : elongationSpecies : Leucaena leucocephala L. de Wit

Biological Species/NCBI Leucaena leucocephala ID Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

0.100000 mg/mL

Measurement Parameter

% Inhibition

Unit

Quantitative value

Measurement pX

3.59

Tran, Dang Xuan; Tsuneaki, Toyama; Masakazu, Fukuta; Tran, Dang Khanh; Shinkichi, Tawata; Journal of Agricultural and Food Chemistry; vol. 57; nb. 20; (2009); p. 9448 - 9453, View in Reaxys 47 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

74/130

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Bioassay Details

Effect : elongation

Biological Species/NCBI Echinochloa crus-galli ID Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

0.100000 mg/mL

Measurement Parameter

% Inhibition

Unit

Quantitative value

59.4

Measurement pX

3.43

Tran, Dang Xuan; Tsuneaki, Toyama; Masakazu, Fukuta; Tran, Dang Khanh; Shinkichi, Tawata; Journal of Agricultural and Food Chemistry; vol. 57; nb. 20; (2009); p. 9448 - 9453, View in Reaxys 48 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : elongation Species : Imperata cylindrica (L.) Beauv.

Biological Species/NCBI Imperata cylindrica ID Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

0.100000 mg/mL

Measurement Parameter

% Stimulation

Unit

Quantitative value

55.6

Tran, Dang Xuan; Tsuneaki, Toyama; Masakazu, Fukuta; Tran, Dang Khanh; Shinkichi, Tawata; Journal of Agricultural and Food Chemistry; vol. 57; nb. 20; (2009); p. 9448 - 9453, View in Reaxys 49 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

inhibitory effect on lettuce germination

Measurement Parameter

Qualitative

Chiji, Hideyuki; Tanaka, Shigenori; Izawa, Masao; Agricultural and Biological Chemistry; vol. 44; nb. 1; (1980); p. 205 - 208, View in Reaxys 50 of 200

Substance Effect

Cytoprotective

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Effect : cell-oxidized LDL-induced cytotoxicityLDL: low-density lipoprotein

Biological Species/NCBI Human ID Cells/Cell Lines

HMEC-1

Substance RN

784514View in Reaxys

Substance Name

65585

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Measurement Parameter

Qualitative

Qualitative value

Belkheiri, Nadji; Bouguerne, Benaissa; Bedos-Belval, Florence; Duran, Hubert; Bernis, Corinne; Salvayre, Robert; Negre-Salvayre, Anne; Baltas, Michel; European Journal of Medicinal Chemistry; vol. 45; nb. 7; (2010); p. 3019 - 3026, View in Reaxys 51 of 200

Substance Effect

Antioxidant

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : HMEC-1-mediated oxidationBioassay : low-density plasma lipoproteinHMEC-1: human microvascular endothelial cells

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Antiinflammatory

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Flux release

Bioassay Details

Effect : fMLP/CB-induced elastase releasefMLP: formyl-L-methionyl-L-leucyl-L-phenylalanine; CB: cytochalasin B

Biological Species/NCBI Human ID Cells/Cell Lines

Neutrophil

Substance RN

784514View in Reaxys

Substance Name

Substance Dose

10 µg/mL

Measurement Parameter

% Inhibition

Unit

Quantitative value

28.6

Measurement pX

3.86

Chen, Jih-Jung; Lin, Yu-Hsien; Day, Shiow-Hwa; Hwang, Tsong-Long; Chen, Ih-Sheng; Food Chemistry; vol. 125; nb. 2; (2011); p. 282 - 287, View in Reaxys 53 of 200

Substance Effect

Antiinflammatory

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : fMLP/CB-induced superoxide anion generationfMLP: formyl-L-methionyl-L-leucylL-phenylalanine; CB: cytochalasin B

Biological Species/NCBI Human ID Cells/Cell Lines

Neutrophil

Substance RN

784514View in Reaxys

76/130

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Substance Name

Substance Dose

10 µg/mL

Measurement Parameter

% Inhibition

Unit

Quantitative value

Measurement pX

Chen, Jih-Jung; Lin, Yu-Hsien; Day, Shiow-Hwa; Hwang, Tsong-Long; Chen, Ih-Sheng; Food Chemistry; vol. 125; nb. 2; (2011); p. 282 - 287, View in Reaxys 54 of 200

Target Mutant/Chimera Details

4-aminobutyrate aminotransferase, mitochondrial:Wild

Target Subunit Proteins

4-aminobutyrate aminotransferase, mitochondrial

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : |enzyme; inhib. of Bioassay : reference: vigabatrin (IC50: 132.89 mg/l) enzyme incubated with GABA+α-ketoglutaric acid and title comp. in potassium phosphate buffer, pH 8.0, 37 deg C for 30 min; NADP+ added, amount of NADPH generated in 20 min measd. as enzyme activity, by spectrophotometry

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

10 mg/L

Qualitative Results

at 10 mg/l moderate (ca. 50 percent) inhibition of GABA transaminase activity, diagram

Measurement Parameter

Qualitative

Target, Subunit, Species 4-aminobutyrate aminotransferase, mitochondrial Ha; Shin; Lee; Kim; Huh; Yong; Planta Medica; vol. 67; nb. 9; (2001); p. 877 - 880, View in Reaxys

55 of 200

Target Subunit Synonyms

(s)-3-amino-2-methylpropionate transaminase (4-aminobutyrate aminotransferase, mitochondrial); 4-aminobutyrate aminotransferase, mitochondrial; abat; gaba aminotransferase (4-aminobutyrate aminotransferase, mitochondrial); gaba transaminase; gaba-at; gaba-t; gabat; gamma-amino-n-butyrate transaminase (4-aminobutyrate aminotransferase, mitochondrial); gta-1; k04d7.3; l-aibat (4-aminobutyrate aminotransferase, mitochondrial); probable 4-aminobutyrate aminotransferase, mitochondrial

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

Agrobacterium virulence inducing activity (A. tumefaciens strain A348)

Measurement Parameter

Qualitative

Delmotte, Francis M.; Delay, Didier; Cizeau, Jeannick; Guerin, Brigitte; Leple, Jean-Charles; Phytochemistry (Elsevier); vol. 30; nb. 11; (1991); p. 3549 - 3552, View in Reaxys 56 of 200

Substance Effect

Cytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Bioassay : mithramycin used as reference comp. (ED50 = 0.06 mg/l)

Cells/Cell Lines

P388 cell line

Substance RN

784514View in Reaxys

77/130

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Substance Name

65585

Measurement Parameter

ED50

Unit

mg/L

Quantitative value

11.7

Measurement pX

4.19

Chou, Hsueh-Chun; Chen, Jih-Jung; Duh, Chang-Yih; Huang, Tur-Fu; Chen, Ih-Sheng; Planta Medica; vol. 71; nb. 11; (2005); p. 1078 - 1081, View in Reaxys 57 of 200

Substance Effect

Cytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Bioassay : mithramycin used as reference comp. (ED50 = 0.08 mg/l)

Cells/Cell Lines

HT 29

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

ED50

Unit

mg/L

Quantitative value

Measurement pX

3.56

Chou, Hsueh-Chun; Chen, Jih-Jung; Duh, Chang-Yih; Huang, Tur-Fu; Chen, Ih-Sheng; Planta Medica; vol. 71; nb. 11; (2005); p. 1078 - 1081, View in Reaxys 58 of 200

Substance Effect

Antiallergic

Bioassay Category

In Vivo (Animal models)

Bioassay Name

In vivo Measurement

Bioassay Details

Effect : IgE-induced PCA reactionTarget : ;skinSpecies : ICR mouse IgE: immunoglobulin E; PCA: passive cutaneous anaphylaxis; mouse injected intradermally with 10 μg antiDNP-BSA into dorsal skin site; colorimetry

Biological Species/NCBI Mus musculus ID Substance RN

784514View in Reaxys

Substance Name

65585

Substance Route of Adm.

oral administration

Qualitative Results

inhibitory dose 200 mg/kg

Measurement Parameter

Qualitative

Substance Effect

Antiallergic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : FCεRI-IgE bindingTarget : ;FCεRI receptorFCεRI: high affinity IgE receptor; IgE: immunoglobulin E; title comp. concentration not explicitly stated by authors; competitive degranulation assay

Biological Species/NCBI Rattus norvegicus ID

78/130

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Cells/Cell Lines

RBL-2H3

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Antiallergic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : phosphorylation of MAPKs in Ag-stimulated cellsTarget : ;ERKtitle comp. concentration not explicitly stated by authors; MAPK: mitogen activated protein kinase; ERK: extracellular signal regulated kinase; JNK: c-jun-N-terminal kinase; immunoblot analysis

Biological Species/NCBI Rattus norvegicus ID Cells/Cell Lines

RBL-2H3

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Route of Adm.

oral administration

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Antiallergic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : phosphorylation of MAPKs in Ag-stimulated cellsTarget : ;JNKtitle comp. concentration not explicitly stated by authors; MAPK: mitogen activated protein kinase; ERK: extracellular signal regulated kinase; JNK: c-jun-N-terminal kinase; immunoblot analysis

Biological Species/NCBI Rattus norvegicus ID Cells/Cell Lines

RBL-2H3

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Route of Adm.

oral administration

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Antiallergic

Bioassay Category

In Vitro (Efficacy)

79/130

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Bioassay Name

In Vitro (others)

Bioassay Details

Effect : phosphorylation of MAPKs in Ag-stimulated cellsTarget : ;p38 MAP kinasetitle comp. concentration not explicitly stated by authors; MAPK: mitogen activated protein kinase; ERK: extracellular signal regulated kinase; JNK: c-jun-N-terminal kinase; immunoblot analysis

Biological Species/NCBI Rattus norvegicus ID Cells/Cell Lines

RBL-2H3

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Route of Adm.

oral administration

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Antiallergic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : phosphorylation of Syk/PLCγs pathway in Ag-stimulated cellstitle comp. concentration not explicitly stated by authors; Syk: spleen tyrosine kinase; PLC: phospholipase C; immunoblot analysis

Biological Species/NCBI Rattus norvegicus ID Cells/Cell Lines

RBL-2H3

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Route of Adm.

oral administration

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Antineoplastic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Effect : cell viabilityMTT assay; MTT: 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide

Cells/Cell Lines

AGS

Substance RN

784514View in Reaxys

Substance Name

Substance Dose

50 µg/mL

Measurement Parameter

% Inhibition

Unit

µM

80/130

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Quantitative value

17.1

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : modulator of shikonin biosynthesisTarget : Lithospermum erythrorhizon Sieb. et Zucc. M18 cellsBioassay : culturing cells in M9 medium + 10 mM MES containing test compound; measurement of shikonin in cells collected

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

1 µM

Measurement Parameter

Qualitative

Qualitative value

Yazaki, Kazufumi; Fukui, Hiroshi; Nishikawa, Yumiko; Tabata, Mamoru; Bioscience, Biotechnology and Biochemistry; vol. 61; nb. 10; (1997); p. 1674 - 1678, View in Reaxys 66 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : suppressing cell growthTarget : Lithospermum erythrorhizon Sieb. et Zucc. M18 cellsBioassay : culturing cells in M9 medium + 10 mM MES containing test compound; harvesting cells; determination of dry weight

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

1 µM

Measurement Parameter

Qualitative

Qualitative value

Yazaki, Kazufumi; Fukui, Hiroshi; Nishikawa, Yumiko; Tabata, Mamoru; Bioscience, Biotechnology and Biochemistry; vol. 61; nb. 10; (1997); p. 1674 - 1678, View in Reaxys 67 of 200

Target Mutant/Chimera Details

enzyme:Wild

Target Subunit Proteins

enzyme

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : |enzyme; inhib. of Bioassay : HBSS: Hank's balanced salt soln.; DMB: 3,3'-dimethoxybenzidine cells incubated with title comp. in HBSS; stimulated with opsonized zymosan (37 deg C, 15 min); centrifuged; supernatants mixed with DMB, H2O2; myeloperoxidase release detd. by measuring absorbance at 450 nm every 2 min for 20 min using ELISA reader

Biological Species/NCBI Human ID Cells/Cell Lines

Neutrophil

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

IC50

Unit

µM

81/130

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Quantitative value

1250

Measurement pX

2.9

Target, Subunit, Species enzyme Van den Worm, Edwin; Beukelman, Cees J.; Van den Berg, Albert J.J.; Kroes, Burt H.; Labadie, Rudi P.; Van Dijk, Hans; European Journal of Pharmacology; vol. 433; nb. 2-3; (2001); p. 225 - 230, View in Reaxys

68 of 200

Target Subunit Synonyms

catalytic; enzyme

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : reactive oxygen species production; inhibition ofBioassay : HBSS: Hanks's balanced salt solution neutrophils treated with title comp.in HBSS, pH 7.35; luminol or lucigenin soln. added; opsonized zymosan A added; chemiluminescence (measure of reactive oxygen species production) monitored every 2 min for 0.5 s during 30-min period using luminometer

Biological Species/NCBI Human ID Cells/Cell Lines

Neutrophil

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

IC50

Unit

µM

Quantitative value

4 - 4.5

Measurement pX

5.4

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : reactive oxygen species production; inhibition ofBioassay : PMA: phorbol 12-myristate 13-acetate; HBSS: Hank's balanced salt soln. neutrophils treated with title comp. in HBSS, pH 7.35; luminol or lucigenin soln. added; PMA added; chemiluminescence (measure of reactive oxygen species production) monitored every 2 min for 0.5 s during 30-min period using luminometer

Biological Species/NCBI Human ID Cells/Cell Lines

Neutrophil

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

IC50

Unit

µM

Quantitative value

4 - 1000

Measurement pX

5.4

Substance Effect

Antioxidant

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

82/130

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Bioassay Details

Target : xanthine oxidaseBioassay : hypoxanthine, lucigenin, and PBS or superoxide dismutase added to 96-well plate containing title comp.; superoxide anion production initiated by enzyme; chemiluminescence monitored every min for 0.5 s during 15-min period using luminometer

Substance RN

784514View in Reaxys

Substance Name

65585

Measurement Parameter

Qualitative

Qualitative value

Substance Effect

Cytotoxic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Bioassay : CFDA: 5-carboxyfluorescein diacetate CFDA-labeled neutrophils (1E7 cells/ml) incubated with title comp. at 37 deg C for 15 min; cells washed and stained with propidium iodide/ink soln.; percentage of dead cells detd. using fluorescence microscope

Biological Species/NCBI Human ID Cells/Cell Lines

Neutrophil

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

500 µM

Measurement Parameter

Qualitative

Qualitative value

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : β-glucans dietary fibersTarget : Glucagel Species : hull-less barley Bioassay : βglucan (Glucagel)

Biological Species/NCBI barley ID Substance RN

784514View in Reaxys

Substance Name

Substance Dose

<= 2 mM

Qualitative Results

ΔA dialysate retention 35 - 38 percent

Measurement Parameter

Qualitative

Simonsen, Henrik Toft; Nielsen, Mette S.; Christensen, Niels J.; Christensen, Ulla; Cour, Thomas V. La; Motawia, Mohammed Saddik; Jespersen, Birthe P.M.; Engelsen, Soren B.; Moller, Birger Lindberg; Journal of Agricultural and Food Chemistry; vol. 57; nb. 5; (2009); p. 2056 - 2064, View in Reaxys 73 of 200

Target Mutant/Chimera Details

Chymotrypsin B:Wild

Target Subunit Proteins

Chymotrypsin B

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

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Bioassay Details

Effect : enzyme activity Bioassay : α-chymotrypsin

Substance RN

784514View in Reaxys

Substance Name

Substance Dose

0.500000 mM

Measurement Parameter

Qualitative

Qualitative value

Target, Subunit, Species Chymotrypsin B Ramsay, Kamdem Soup T.; Wafo, Pascal; Ali, Zulfiqar; Khan, Ajmal; Oluyemisi, Ogbole O.; Marasini, Bishnu P.; Khan, Ikhlas A.; Bonaventure, Ngadjui T.; Choudhary, M. Iqbal; Atta-Ur-Rahman; Fitoterapia; vol. 83; nb. 1; (2012); p. 204 - 208, View in Reaxys

74 of 200

Target Subunit Synonyms

chymotrypsin b

Target Mutant/Chimera Details

urease:Wild

Target Subunit Proteins

urease

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activity Bioassay : urease

Biological Species/NCBI Canavalia ensiformis ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

µM

Quantitative value

432.2

Measurement pX

3.36

Target, Subunit, Species urease Ramsay, Kamdem Soup T.; Wafo, Pascal; Ali, Zulfiqar; Khan, Ajmal; Oluyemisi, Ogbole O.; Marasini, Bishnu P.; Khan, Ikhlas A.; Bonaventure, Ngadjui T.; Choudhary, M. Iqbal; Atta-Ur-Rahman; Fitoterapia; vol. 83; nb. 1; (2012); p. 204 - 208, View in Reaxys

75 of 200

Target Subunit Synonyms

afua_1g04560; at1g67550; cnag_05540; cnbl1900; cnh01900; f12b7.10; loc_os12g13270; os12g0234800; osj_35660; spac1952.11c; ure; ure1 (urease); urea amidohydrolase; urease

Substance Effect

Antioxidant

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : antioxidativeBioassay : oxygen radicalORAC: oxygen reducing absorbance capacity; 1 ORAC unit equals the inhibition of the declining fluorescence produced by 1 μmol/l of trolox

Substance RN

784514View in Reaxys

Substance Name

VIII

Qualitative Results

ORAC 1.62 units

Measurement Parameter

Qualitative

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Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.; Food Chemistry; vol. 133; nb. 3; (2012); p. 697 - 706, View in Reaxys 76 of 200

Substance Effect

Antioxidant

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : antioxidativeBioassay : hypoxanthine/xanthine oxidaseHPLC; DHBA production was determined

Substance RN

784514View in Reaxys

Substance Name

VIII

Measurement Parameter

IC50

Unit

µM

Quantitative value

2.25

Measurement pX

5.65

Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.; Food Chemistry; vol. 133; nb. 3; (2012); p. 697 - 706, View in Reaxys 77 of 200

Substance Effect

Antioxidant

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : free radical scavengingBioassay : DPPH radicalDPPH: 1,1-diphenyl-2-picrylhydrazyl

Substance RN

784514View in Reaxys

Substance Name

VIII

Measurement Parameter

IC50

Unit

µM

Quantitative value

1015

Measurement pX

2.99

Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.; Food Chemistry; vol. 133; nb. 3; (2012); p. 697 - 706, View in Reaxys 78 of 200

Target Mutant/Chimera Details

alpha-glucosidase [Rattus norvegicus]:Wild

Target Species (Bioactivity)

Rattus norvegicus

Target Subunit Proteins

alpha-glucosidase [Rattus norvegicus]

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activity Bioassay : intestinal α-glucosidaseunit not explicitly stated

Biological Species/NCBI Rattus norvegicus ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

Qualitative

Qualitative value

Target, Subunit, Species alpha-glucosidase [Rattus norvegicus]

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Ayinampudi, Sridhar Rao; Domala, Ramesh; Merugu, Ramchander; Bathula, Sreenivasulu; Janaswamy, Madhusudana Rao; Fitoterapia; vol. 83; nb. 1; (2012); p. 88 - 92, View in Reaxys

79 of 200

Target Subunit Synonyms

alpha-glucosidase

Substance Effect

Antioxidant

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : radical scavengingBioassay : 1,1-diphenyl-2-picrylhydrazyl radicalSC50: concentration of the sample required to scavenge 50% of the test system

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

Qualitative

Qualitative value

Ayinampudi, Sridhar Rao; Domala, Ramesh; Merugu, Ramchander; Bathula, Sreenivasulu; Janaswamy, Madhusudana Rao; Fitoterapia; vol. 83; nb. 1; (2012); p. 88 - 92, View in Reaxys 80 of 200

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Cells/Cell Lines

L-1210 cell line

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

pIC50

Quantitative value

3.1

Measurement pX

3.1

Selassie, Cynthia D.; Kapur, Sanjay; Verma, Rajeshwar P.; Rosario, Melissa; Journal of Medicinal Chemistry; vol. 48; nb. 23; (2005); p. 7234 - 7242, View in Reaxys

81 of 200

Compound RN

1723797

Compound name

Glutamine

Compound role

COM

Target Mutant/Chimera Details

Caspase [Mus musculus]:Wild

Target Species (Bioactivity)

Mus musculus

Target Subunit Proteins

Caspase [Mus musculus]

Target Transfection

Non Transfected

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology stimulation

Cells/Cell Lines

L-1210 cell line

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

pEC50

Quantitative value

2.9

Measurement pX

2.9

Target, Subunit, Species Caspase [Mus musculus]

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Selassie, Cynthia D.; Kapur, Sanjay; Verma, Rajeshwar P.; Rosario, Melissa; Journal of Medicinal Chemistry; vol. 48; nb. 23; (2005); p. 7234 - 7242, View in Reaxys

82 of 200

Target Subunit Synonyms

caspase

Compound RN

1723797

Compound name

Glutamine

Compound role

VPR

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

potent and selective cytotoxicity against the cells: P-388 ED50=3.28 μg/ml, and lack of cytotoxicity against: KB ED50>10 μg/ml, A-549 ED50>10 μg/ml, HT-29 ED50>10 μg/ml, HL-60 ED50>10 μg/ml

Measurement Parameter

Qualitative

Wu; Chang; Ko; Teng; Planta Medica; vol. 61; nb. 2; (1995); p. 146 - 149, View in Reaxys 83 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

inhibition of Bacillus subtilis (MIC >/= 250 μg/ml), Straphylococcus aureus (MIC >/= 250 μg/ml); antifungal activity against H. teres (80percent)

Measurement Parameter

Qualitative

Kokpol, Udom; Chavasiri, Warinthorn; Chittawong, Vallapa; Bruce, Marc; Cunningham, G. N.; et al.; Phytochemistry (Elsevier); vol. 33; nb. 5; (1993); p. 1129 - 1132, View in Reaxys 84 of 200

Substance Effect

Antiprotozoal

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Biological Species/NCBI Plasmodium falciparum 3D7 ID Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

0.500000 mg/L

Measurement Parameter

IC50

Unit

mg/L

Quantitative value

Measurement pX

4.15

Cheplogoi, Peter K.; Mulholland, Dulcie A.; Coombes, Philip H.; Randrianarivelojosia, Milijaona; Phytochemistry; vol. 69; nb. 6; (2008); p. 1384 - 1388, View in Reaxys 85 of 200

Substance Effect

Antiprotozoal

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Target : Plasmodium falciparum FCM29

Substance RN

784514View in Reaxys

87/130

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Substance Name

65585

Substance Dose

0.500000 mg/L

Measurement Parameter

IC50

Unit

mg/L

Quantitative value

21.4

Measurement pX

3.93

Cheplogoi, Peter K.; Mulholland, Dulcie A.; Coombes, Philip H.; Randrianarivelojosia, Milijaona; Phytochemistry; vol. 69; nb. 6; (2008); p. 1384 - 1388, View in Reaxys 86 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

It has inhibitory activity on cyclic adenosine 3',5'-monophosphate phosphodiesterase.

Measurement Parameter

Qualitative

Nikaido; Sung; Ohmoto; Sankawa; Chemical and Pharmaceutical Bulletin; vol. 32; nb. 2; (1984); p. 578 - 584, View in Reaxys 87 of 200

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : antiproliferativeAntiproliferative Activities of Isolated Phenolics from Maple Syrup on Colon Cells The antiproliferative activities of phenolics previously isolated from maple syrup extracts are evaluated after both 48 and 72 h of treatment (Table 14). All of the pure compounds inhibited proliferation of the HCT-1

Biological Species/NCBI Human ID Cells/Cell Lines

HT 29

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

µM

Quantitative value

90.7

Measurement pX

4.04

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Biological Species/NCBI Human ID Cells/Cell Lines

CACO2

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Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

µM

Quantitative value

59.4

Measurement pX

4.23

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Biological Species/NCBI Human ID Cells/Cell Lines

HCT116

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

µM

Quantitative value

66.8

Measurement pX

4.18

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Biological Species/NCBI Human ID Cells/Cell Lines

HT 29

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

µM

Quantitative value

90.7

Measurement pX

4.04

Patent; SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie; (168 pag.); WO2012/21981; (A1); (2012), View in Reaxys

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91 of 200

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Biological Species/NCBI Human ID Cells/Cell Lines

CACO2

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

µM

Quantitative value

59.4

Measurement pX

4.23

Patent; SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie; (168 pag.); WO2012/21981; (A1); (2012), View in Reaxys 92 of 200

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Biological Species/NCBI Human ID Cells/Cell Lines

HCT116

Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

µM

Quantitative value

66.8

Measurement pX

4.18

Patent; SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie; (168 pag.); WO2012/21981; (A1); (2012), View in Reaxys 93 of 200

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Biological Species/NCBI Human ID Cells/Cell Lines

HT 29

Substance RN

784514View in Reaxys

90/130

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Substance Name

Qualitative Results

IC50 (μmol/l) = 90.7, 68.6 after 48, 72 h treatment, respectively

Measurement Parameter

Qualitative

Patent; SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie; (168 pag.); WO2012/21981; (A1); (2012), View in Reaxys 94 of 200

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Biological Species/NCBI Human ID Cells/Cell Lines

CACO2

Substance RN

784514View in Reaxys

Substance Name

Qualitative Results

IC50 (μmol/l) = 59.4, 35.9 after 48, 72 h treatment, respectively

Measurement Parameter

Qualitative

Patent; SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie; (168 pag.); WO2012/21981; (A1); (2012), View in Reaxys 95 of 200

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Biological Species/NCBI Human ID Cells/Cell Lines

HCT116

Substance RN

784514View in Reaxys

Substance Name

Qualitative Results

IC50 (μmol/l) = 66.8, 56.3 after 48, 72 h treatment, respectively

Measurement Parameter

Qualitative

Patent; SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie; (168 pag.); WO2012/21981; (A1); (2012), View in Reaxys 96 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : |metabolic Target : laccase from Trametes villosaBioassay : effect on biotransformation of 4ADNT was investigated in 0.1 M citric-phosphate buffer, pH 6.8; after mixing 0.1 mM 4-amino-2,6-dinitrotoluene (4ADNT) with equimolar amounts of title comp. in total volume of 5 ml., the laccase (18 DMP units ml-1) was added; incubation at 25 deg C in the dark

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

0.100000 mM

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Qualitative Results

in the presence of title comp. up to ca. 68 percent of 4ADNT was transformed

Measurement Parameter

Qualitative

Wang; Thiele; Bollag; Archives of Environmental Contamination and Toxicology; vol. 42; nb. 1; (2002); p. 1 - 8, View in Reaxys 97 of 200

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Effect : hair-regrowth stimulantTarget : C3H/He mouseBioassay : G.A.( percent) = (1 (mean luminance of treated group/mean luminance of control group))*100 in vivo; effect on hair-regrowth assayed; hair on the back of 9-week-old mice were shaved; luminance of depilated area measured on day 13 after title comp. application using colorimeter; results expressed as relative growth activity (G.A.)

Substance RN

784514View in Reaxys

Substance Name

65585

Qualitative Results

at dose of 0.01/0.1/0.5 mg G.A. was -0.2/5.3/9.6 percent

Measurement Parameter

Qualitative

Ishida, Hitoshi; Inaoka, Yasunori; Shibatani, Jun-Ichi; Fukushima, Makoto; Tsuji, Kuniro; Biological and Pharmaceutical Bulletin; vol. 22; nb. 11; (1999); p. 1189 - 1192, View in Reaxys 98 of 200

Substance Effect

Antiproliferative

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

In Vitro (others)

Bioassay Details

Target : Leucoagaricus gongylophorus SingerBioassay : L. gangylophorus: symbiotic fungus of leaf-cutting ants (Atta sexdens rubropilosa)

Substance RN

784514View in Reaxys

Substance Name

65585

Substance Dose

50 mg/L

Qualitative Results

percent growth inhibition: 80

Measurement Parameter

Qualitative

Target Mutant/Chimera Details

epidermal growth factor-activated receptor:Wild

Target Subunit Proteins

epidermal growth factor-activated receptor

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : EGF-R kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

92/130

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Quantitative value

2.3E-06

Measurement pX

4.9

Target, Subunit, Species epidermal growth factor-activated receptor Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms 100 of 200 Target Mutant/Chimera Details

egf receptor; egfr (epidermal growth factor-activated receptor); epidermal growth factor receptor (epidermal growth factor-activated receptor); epidermal growth factor-activated receptor; tgf-alpha receptor; transforming growth factor-alpha receptor Insulin receptor:Wild

Target Subunit Proteins

Insulin receptor

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : INS-R kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

2.2E-06

Measurement pX

4.92

Target, Subunit, Species Insulin receptor Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms 101 of 200 Target Mutant/Chimera Details

insr; insulin receptor; ir; xe-insr; xtk-1b Cyclin-dependent kinase 2:Wild + CDK2/Cyclin (Cyclin A):Wild

Target Subunit Proteins

Cyclin-dependent kinase 2;+CDK2/Cyclin (Cyclin A)

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : CDK2/CycA kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Qualitative value

Quantitative value

1E-05

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Measurement pX

Target, Subunit, Species CDK2/Cyclin (Cyclin A); Cyclin-dependent kinase 2 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms

102 of 200 Target Mutant/Chimera Details

cdc2 homolog eg1 protein kinase; cdc2c (cyclin-dependent kinase 2); cdk2; cdkn2 (cyclindependent kinase 2); cdkn7 (cyclin-dependent kinase 2); cell division control protein 2 cognate; cell division protein kinase 2 (cyclin-dependent kinase 2); cg10498; cyclin-dependent kinase 2; eg1 (cyclin-dependent kinase 2); p33 protein kinase; cdk2/cyclin (cyclin a) Cyclin-dependent kinase 4:Wild + G1/S-specific cyclin-D1:Wild

Target Subunit Proteins

Cyclin-dependent kinase 4;+G1/S-specific cyclin-D1

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : CDK4/CycD1 kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

4.7E-06

Measurement pX

4.59

Target, Subunit, Species Cyclin-dependent kinase 4; G1/S-specific cyclin-D1 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms 103 of 200 Target Mutant/Chimera Details

cdk4; cell division protein kinase 4; crk3 (cyclin-dependent kinase 4); cyclin-dependent kinase 4; psk-j3; b-cell lymphoma 1 protein; bcl-1; bcl-1 oncogene; bcl1; ccnd1; cycd1 (g1/s-specific cyclin-d1); cyl-1; g1/s-specific cyclin-d1; prad1; prad1 oncogene Aurora kinase A:Wild

Target Subunit Proteins

Aurora kinase A

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : Aurora-A kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

8.4E-06

94/130

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Measurement pX

4.34

Target, Subunit, Species Aurora kinase A Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms

104 of 200 Target Mutant/Chimera Details

aik; air-2 (aurora kinase a); airk; airk1; ark-1; ark1 (aurora kinase a); at2g25880; at4g32830; ataur1; ataur2; aur1 (aurora kinase a); aur2; aura; aurka (aurora kinase a); aurora 2; aurora family kinase 1; aurora kinase a; aurora-like kinase 1; aurora-like kinase 2; aurora-related kinase 1; aurora/ipl1-related kinase 1 (aurora kinase a); aurora/ipl1-related protein kinase 2 (aurora kinase a); ayk1; b0207.4; breast tumor-amplified kinase; btak; f17h15.9; hark1; iak1; ipl1- and aurora-related kinase 1; rataura; serine/threonine-protein kinase 15; serine/threonine-protein kinase 6; serine/threonine-protein kinase aurora-1; serine/threonine-protein kinase aurora-2; serine/threonine-protein kinase aurora-a (aurora kinase a); serine/threonine-protein kinase aurora-b (aurora kinase a); serine/threonineprotein kinase ayk1; stk15; stk6 (aurora kinase a); stu-7; t16i18.40 Vascular endothelial growth factor receptor 2:Wild

Target Subunit Proteins

Vascular endothelial growth factor receptor 2

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : VEGF-R2 kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

1.2E-06

Measurement pX

5.18

Target, Subunit, Species Vascular endothelial growth factor receptor 2 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms

105 of 200 Target Mutant/Chimera Details

ek1 (vascular endothelial growth factor receptor 2); endothelial kinase receptor ek1; fetal liver kinase 1 (vascular endothelial growth factor receptor 2); fetal liver kinase 1b; flk-1; flk-1b; flk1 (vascular endothelial growth factor receptor 2); flk1b; kdr (vascular endothelial growth factor receptor 2); kdrb; kinase insert domain receptor; kinase insert domain receptor-b; kinase nyk; protein-tyrosine kinase receptor flk-1 (vascular endothelial growth factor receptor 2); protein-tyrosine kinase receptor flk-1b; quek 1; quek1; si:busm1-205d10.1; si:ch211-254j6.1; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor 2 homolog b; vegfr-2; vegfr-2 homolog b; vegfr2 (vascular endothelial growth factor receptor 2) Platelet-derived growth factor receptor beta:Wild

Target Subunit Proteins

Platelet-derived growth factor receptor beta

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : PDGFR-beta kinase

95/130

2017-10-08 12:35:19

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

4.8E-06

Measurement pX

4.58

Target, Subunit, Species Platelet-derived growth factor receptor beta Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms

106 of 200 Target Mutant/Chimera Details

beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; cd140 antigen-like family member b; pdgf-r-beta; pdgfr (platelet-derived growth factor receptor beta); pdgfr-1; pdgfr-beta; pdgfr1; pdgfrb; platelet-derived growth factor receptor 1; platelet-derived growth factor receptor beta Proto-oncogene tyrosine-protein kinase Src:Wild

Target Subunit Proteins

Proto-oncogene tyrosine-protein kinase Src

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : SRC kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

6.9E-07

Measurement pX

5.42

Target, Subunit, Species Proto-oncogene tyrosine-protein kinase Src Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms 107 of 200 Target Mutant/Chimera Details

cg7524; dsrc64; neuronal proto-oncogene tyrosine-protein kinase src; p60-src; pp60c-src; proto-oncogene c-src; proto-oncogene tyrosine-protein kinase src; src; src1 (proto-oncogene tyrosine-protein kinase src); src64b; tyrosine-protein kinase src64b Receptor-type tyrosine-protein kinase FLT3:Wild

Target Subunit Proteins

Receptor-type tyrosine-protein kinase FLT3

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : FLT3 kinase

96/130

2017-10-08 12:35:19

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

5.6E-07

Measurement pX

5.51

Target, Subunit, Species Receptor-type tyrosine-protein kinase FLT3 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms

108 of 200 Target Mutant/Chimera Details

cd135; fetal liver kinase 2; fetal liver kinase-2; fl cytokine receptor; flk-2; flk2; flt-3; flt3; fms-like tyrosine kinase 3; receptor-type tyrosine-protein kinase flt3; stem cell tyrosine kinase 1; stk-1; stk1 (receptor-type tyrosine-protein kinase flt3); tyrosine-protein kinase receptor flk-2 Vascular endothelial growth factor receptor 3:Wild

Target Subunit Proteins

Vascular endothelial growth factor receptor 3

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : VEGF-R3 kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

2.9E-06

Measurement pX

4.8

Target, Subunit, Species Vascular endothelial growth factor receptor 3 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms 109 of 200 Target Mutant/Chimera Details

endothelial kinase receptor ek2; flt-4; flt4; fms-like tyrosine kinase 4; k2 (vascular endothelial growth factor receptor 3); quek 2; quek2; tyrosine-protein kinase receptor flt4; vascular endothelial growth factor receptor 3; vegfr-3; vegfr3 Angiopoietin-1 receptor:Wild

Target Subunit Proteins

Angiopoietin-1 receptor

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : TIE2 kinase

97/130

2017-10-08 12:35:19

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

5.1E-06

Measurement pX

4.55

Target, Subunit, Species Angiopoietin-1 receptor Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

110 of 200

Target Subunit Synonyms

angiopoietin-1 receptor; endothelial tyrosine kinase; htie2; hyk; mtie2; p140 tek; stk1 (angiopoietin-1 receptor); tek (angiopoietin-1 receptor); tie-2 (angiopoietin-1 receptor); tie2 (angiopoietin-1 receptor); tunica interna endothelial cell kinase; tyrosine kinase with ig and egf homology domains-2 (angiopoietin-1 receptor); tyrosine-protein kinase receptor tek; tyrosine-protein kinase receptor tie-2 (angiopoietin-1 receptor); vmcm; vmcm1

Target Mutant/Chimera Details

Hepatocyte growth factor receptor:Wild

Target Subunit Proteins

Hepatocyte growth factor receptor

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : MET kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

4.8E-06

Measurement pX

4.58

Target, Subunit, Species Hepatocyte growth factor receptor Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

111 of 200

Target Subunit Synonyms

hepatocyte growth factor receptor; hgf receptor; hgf/sf receptor; met (hepatocyte growth factor receptor); proto-oncogene c-met; scatter factor receptor; sf receptor; tyrosine-protein kinase met

Target Mutant/Chimera Details

Aurora kinase B:Wild

Target Subunit Proteins

Aurora kinase B

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : Aurora-B kinase

98/130

2017-10-08 12:35:19

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

3.2E-06

Measurement pX

4.75

Target, Subunit, Species Aurora kinase B Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

112 of 200

Target Subunit Synonyms

aik2; aim-1; aim1 (aurora kinase b); airk2; ark-2; ark2 (aurora kinase b); aurkb; aurora 1; aurora kinase b; aurora- and ipl1-like midbody-associated protein 1; aurora-related kinase 2; aurora/ipl1-related kinase 2; serine/threonine kinase a; serine/threonine-protein kinase 12; serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-b (aurora kinase b); stk-1 (aurora kinase b); stk1 (aurora kinase b); stk12; stk5; stka (aurora kinase b); xairk2; xaurora-b

Target Mutant/Chimera Details

Probable serine/threonine-protein kinase PLK:Wild

Target Subunit Proteins

Probable serine/threonine-protein kinase PLK

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : PLK1 kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

8.4E-06

Measurement pX

4.34

Target, Subunit, Species Probable serine/threonine-protein kinase PLK Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

113 of 200

Target Subunit Synonyms

ddb_g0274503; plk (probable serine/threonine-protein kinase plk); polo-like kinase; probable serine/threonine-protein kinase plk

Target Mutant/Chimera Details

Receptor tyrosine-protein kinase erbB-2:Wild

Target Subunit Proteins

Receptor tyrosine-protein kinase erbB-2

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : ERBB2 kinase

99/130

2017-10-08 12:35:19

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

3E-06

Measurement pX

4.78

Target, Subunit, Species Receptor tyrosine-protein kinase erbB-2 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

114 of 200

Target Subunit Synonyms

epidermal growth factor receptor-related protein (receptor tyrosine-protein kinase erbb-2); erbb2 (receptor tyrosine-protein kinase erbb-2); her2 (receptor tyrosine-protein kinase erbb-2); kiaa3023; metastatic lymph node gene 19 protein; mln 19; mln19; neu (receptor tyrosine-protein kinase erbb-2); ngl (receptor tyrosine-protein kinase erbb-2); p185erbb2; p185neu; proto-oncogene c-erbb-2; proto-oncogene neu; receptor tyrosine-protein kinase erbb-2; tyrosine kinase-type cell surface receptor her2

Target Mutant/Chimera Details

Focal adhesion kinase 1:Wild

Target Subunit Proteins

Focal adhesion kinase 1

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : FAK kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

7.4E-06

Measurement pX

4.39

Target, Subunit, Species Focal adhesion kinase 1 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

115 of 200

Target Subunit Synonyms

fadk (focal adhesion kinase 1); fadk 1; fak; fak1; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; frnk; kiaa4203; p125fak; p41/p43frnk; pp125fak; ppp1r71; protein phosphatase 1 regulatory subunit 71; protein-tyrosine kinase 2; ptk2 (focal adhesion kinase 1)

Target Mutant/Chimera Details

Ephrin type-B receptor 4:Wild

Target Subunit Proteins

Ephrin type-B receptor 4

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

100/130

2017-10-08 12:35:19

Bioassay Details

Effect : enzyme activityBioassay : EPHB4 kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

3.2E-06

Measurement pX

4.75

Target, Subunit, Species Ephrin type-B receptor 4 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

116 of 200

Target Subunit Synonyms

developmental kinase 2; ephb4; ephrin type-b receptor 4; hepatoma transmembrane kinase; htk; mdk-2; mdk2; myk1; tyro11; tyrosine kinase myk-1; tyrosine-protein kinase tyro11

Target Mutant/Chimera Details

Insulin-like growth factor 1 receptor:Wild

Target Subunit Proteins

Insulin-like growth factor 1 receptor

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : IGF1-R kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

4.9E-07

Measurement pX

5.57

Target, Subunit, Species Insulin-like growth factor 1 receptor Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

117 of 200

Target Subunit Synonyms

abnormal dauer formation protein 2; cg18402; daf-2; dinr; dir; dir-a; dirh; igf-i receptor; igf1r; inr (insulin-like growth factor 1 receptor); inr-a; insulin-like growth factor 1 receptor; insulin-like growth factor i receptor; insulin-like receptor (insulin-like growth factor 1 receptor); ir; xigf-1r; xigfr; y55d5a.5

Target Mutant/Chimera Details

Serine/threonine-protein kinase PLK4:Wild

Target Subunit Proteins

Serine/threonine-protein kinase PLK4

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : SAK kinase

101/130

2017-10-08 12:35:19

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

4.3E-07

Measurement pX

5.63

Target, Subunit, Species Serine/threonine-protein kinase PLK4 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

118 of 200

Target Subunit Synonyms

aael009360; cg7186; cpij004252; ga20166; gd12112; ge22325; gf10707; gg13228; gh16744; gi13469; gj11832; gk17621; gl11903; gm22133; plk-4; plk4; polo-like kinase 4; sak (serine/threonine-protein kinase plk4); serine/threonine-protein kinase 18; serine/ threonine-protein kinase plk4; serine/threonine-protein kinase sak; stk18; v1g246408

Target Mutant/Chimera Details

Mitogen-activated protein kinase kinase kinase 8:Wild

Target Subunit Proteins

Mitogen-activated protein kinase kinase kinase 8

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : COT kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

5.7E-06

Measurement pX

4.5

Target, Subunit, Species Mitogen-activated protein kinase kinase kinase 8 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys

119 of 200

Target Subunit Synonyms

cancer osaka thyroid oncogene; cot (mitogen-activated protein kinase kinase kinase 8); estf; map3k8; mitogen-activated protein kinase kinase kinase 8; proto-oncogene c-cot; serine/threonine-protein kinase cot; tpl-2; tpl2; tumor progression locus 2

Target Mutant/Chimera Details

Serine/threonine-protein kinase B-raf (V600E):Wild

Target Subunit Proteins

Serine/threonine-protein kinase B-raf (V600E)

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : B-RAF-VE kinase

102/130

2017-10-08 12:35:19

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

8.2E-06

Measurement pX

4.35

Target, Subunit, Species Serine/threonine-protein kinase B-raf (V600E) Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms 120 of 200 Target Mutant/Chimera Details

serine/threonine-protein kinase b-raf (v600e) NUAK family SNF1-like kinase 1:Wild

Target Subunit Proteins

NUAK family SNF1-like kinase 1

Target Transfection

Non Transfected

Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : ARK5 kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Quantitative value

2.4E-06

Measurement pX

4.88

Target, Subunit, Species NUAK family SNF1-like kinase 1 Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys Target Subunit Synonyms 121 of 200 Substance Effect

ampk-related protein kinase 5; ark5; kiaa0537; nuak family snf1-like kinase 1; nuak1; omphalocele kinase 1; omphk1 Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : AKT1 kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

103/130

2017-10-08 12:35:19

Qualitative value

Quantitative value

1E-05

Measurement pX

Shi, Cui; Xu, Min-Juan; Bayer, Mirko; Deng, Zhi-Wei; Kubbutat, Michael H.G.; Waejen, Wim; Proksch, Peter; Lin, Wen-Han; Phytochemistry; vol. 71; nb. 4; (2010); p. 435 - 442, View in Reaxys 122 of 200 Substance Effect

Antineoplastic

Bioassay Category

In Vitro (Efficacy)

Bioassay Name

Enzymology inhibition

Bioassay Details

Effect : enzyme activityBioassay : CK2-alpha1 kinase

Biological Species/NCBI Human ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

IC50

Unit

g/mL

Qualitative value

Quantitative value

1E-05

Measurement pX

Anti-Tuberculosis

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Bioassay Details

Effect : antimycobacterialSpecies : Mycobacterium tuberculosis H37Rv ATCC 27294MIC: lowest concentration of title comp. that completely inhibits test microorganism growth, as detected by unaided eye

Biological Species/NCBI Mycobacterium tuberculosis ID Substance RN

784514View in Reaxys

Substance Name

Measurement Parameter

MIC

Unit

µg/mL

Quantitative value

Measurement pX

3.36

Kuo, Hsiou-Ting; Peng, Chien-Fang; Huang, Hung-Yi; Lin, Chu-Hung; Chen, Ih-Sheng; Tsai, Ian-Lih; Planta Medica; vol. 77; nb. 7; (2011); p. 736 - 741, View in Reaxys 124 of 200 Substance Effect

Antihyperglycemic

Bioassay Category

In Vitro (Efficacy)

Bioassay Details

In vivo percent plasma glucose level in normal Male Wistar Rat (n=8) upon intravenous administration of 7.2 mg/kg compound after 60 minutes

Biological Species/NCBI Rattus norvegicus ID Cells/Cell Lines

Plasma cell

Substance RN

784514View in Reaxys

104/130

2017-10-08 12:35:19

Substance Route of Adm.

intravenous administration

Measurement Parameter

Unit

Qualitative value

Quantitative value

25.93

Deviation

5.63

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys Measurement Object 125 of 200 Substance Effect

PLASMA GLUCOSE LEVELS Antihyperglycemic

Bioassay Category

In Vivo (Animal models)

Bioassay Details

In vivo percent plasma glucose level in fasting Streptozotocin induced Diabetic Male Wistar Rat (n=8) upon intravenous administration of 1.8 mg/kg compound after 60 minutes

Biological Species/NCBI Rattus norvegicus ID Cells/Cell Lines

Plasma cell

Substance RN

784514View in Reaxys

Substance Route of Adm.

intravenous administration

Measurement Parameter

Unit

Qualitative value

Quantitative value

11.08

Deviation

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys Measurement Object 126 of 200 Substance Effect

PLASMA GLUCOSE LEVELS Antihyperglycemic

Bioassay Category

In Vitro (Efficacy)

Bioassay Details

In vivo percent plasma glucose level in fasting Streptozotocin induced Diabetic Male Wistar Rat (n=8) upon intravenous administration of 7.2 mg/kg compound after 60 minutes

Biological Species/NCBI Rattus norvegicus ID Cells/Cell Lines

Plasma cell

Substance RN

784514View in Reaxys

Substance Route of Adm.

intravenous administration

Measurement Parameter

Unit

Qualitative value

Quantitative value

31.29

Deviation

2.07

Huang, Chia-Hsin; Chen, Mei-Fen; Chung, Hsien-Hui; Cheng, Juei-Tang; Journal of Natural Products; vol. 75; nb. 8; (2012); p. 1465 - 1468, View in Reaxys

105/130

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Measurement Object 127 of 200 Bioassay Category Bioassay Details

PLASMA GLUCOSE LEVELS In Vitro (Efficacy) Percent of TPA-induced (Epstein-Barr virus early antigen)EBV-EA activation in the Raji cells after treatment with the compound at 3.2 nmol concentration with respect to positive control (100)

Biological Species/NCBI Human herpesvirus 4 ID Cells/Cell Lines

Raji

Substance RN

784514View in Reaxys

Measurement Parameter

Activation

Unit

Qualitative value

Quantitative value

77.2

Deviation

1.2

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 1348, View in Reaxys 128 of 200 Bioassay Category Bioassay Details

In Vitro (Efficacy) Percent of TPA-induced (Epstein-Barr virus early antigen)EBV-EA activation in the Raji cells after treatment with the compound at 16 nmol concentration with respect to positive control (100)

Biological Species/NCBI Human herpesvirus 4 ID Cells/Cell Lines

Raji

Substance RN

784514View in Reaxys

Measurement Parameter

Activation

Unit

Qualitative value

Quantitative value

39.2

Deviation

2.2

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 1348, View in Reaxys 129 of 200 Bioassay Category Bioassay Details

In Vitro (Efficacy) Percent viability of human Raji cells after 2 days of treatment with compound at 3.2 nmol concentration

Biological Species/NCBI Human ID Cells/Cell Lines

Raji

Substance RN

784514View in Reaxys

Measurement Parameter

Unit

Qualitative value

Quantitative value

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 1348, View in Reaxys Measurement Object

Viability rate

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130 of 200 Bioassay Category Bioassay Details

In Vitro (Efficacy) Percent viability of human Raji cells after 2 days of treatment with compound at 32 nmol concentration

Biological Species/NCBI Human ID Cells/Cell Lines

Raji

Substance RN

784514View in Reaxys

Measurement Parameter

Unit

Qualitative value

Quantitative value

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 1348, View in Reaxys Measurement Object 131 of 200 Bioassay Category Bioassay Details

Viability rate In Vitro (Efficacy) Percent viability of human Raji cells after 2 days of treatment with compound at 16 nmol concentration

Biological Species/NCBI Human ID Cells/Cell Lines

Raji

Substance RN

784514View in Reaxys

Measurement Parameter

Unit

Qualitative value

Quantitative value

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 1348, View in Reaxys Measurement Object 132 of 200 Bioassay Category Bioassay Details

Viability rate In Vitro (Efficacy) Percent of TPA-induced (Epstein-Barr virus early antigen)EBV-EA activation in the Raji cells after treatment with the compound at 0.32 nmol concentration with respect to positive control (100)

Biological Species/NCBI Human herpesvirus 4 ID Cells/Cell Lines

Raji

Substance RN

784514View in Reaxys

Measurement Parameter

Activation

Unit

Qualitative value

Quantitative value

94.7

Deviation

1.5

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 1348, View in Reaxys 133 of 200 Bioassay Category

In Vitro (Efficacy)

107/130

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Bioassay Details

Percent of TPA-induced (Epstein-Barr virus early antigen)EBV-EA activation in the Raji cells after treatment with the compound at 32 nmol concentration with respect to positive control (100)

Biological Species/NCBI Human herpesvirus 4 ID Cells/Cell Lines

Raji

Substance RN

784514View in Reaxys

Measurement Parameter

Activation

Unit

Qualitative value

Quantitative value

4.1

Deviation

0.3

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 1348, View in Reaxys 134 of 200 Bioassay Category Bioassay Details

In Vitro (Efficacy) Percent viability of human Raji cells after 2 days of treatment with compound at 0.32 nmol concentration

Biological Species/NCBI Human ID Cells/Cell Lines

Raji

Substance RN

784514View in Reaxys

Measurement Parameter

Unit

Qualitative value

Quantitative value

Ito; Itoigawa; Otsuka; Tokuda; Nishino; Furukawa; Journal of Natural Products; vol. 63; nb. 10; (2000); p. 1344 1348, View in Reaxys Measurement Object 135 of 200 Bioassay Category Bioassay Details

Viability rate In Vitro (Efficacy) In vitro minimum inhibitory concentration of the compound against Mycobacterium tuberculosis 90-221387 upon incubation at 35 degree C for 2 weeks by proportion method

Biological Species/NCBI Mycobacterium tuberculosis 90 221387 ID Substance RN

784514View in Reaxys

Measurement Parameter

MIC

Unit

µM

Qualitative value

Quantitative value

137.26

Measurement pX

3.86

Chen, Fu-Chi; Peng, Chien-Fang; Tsai, Ian-Lih; Chen, Ih-Sheng; Journal of Natural Products; vol. 68; nb. 9; (2005); p. 1318 - 1323, View in Reaxys Measurement Object 136 of 200 Target Mutant/Chimera Details

Minimum Inhibitory Concentration Tyrosinase [mushroom]:Wild

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Substance Action on Target

Inhibitor

Target Species (Bioactivity)

mushroom

Target Subunit Proteins

Tyrosinase [mushroom]

Bioassay Category

In Vitro (Efficacy)

Bioassay Details

Inhibitory activity against mushroom tyrosinase (200 Units/mg) using L-DOPA as substrate upon incubation for 3 min at 37 degree C and pH 6.8 with the compound dissolved in DMSO (Preincubation time 10 min)

Biological Species/NCBI mushroom ID Substance RN

784514View in Reaxys

Measurement Parameter

IC50

Unit

µM

Qualitative value

Quantitative value

4000

Measurement pX

Target, Subunit, Species Tyrosinase [mushroom] Ley, Jakob P; Bertram, Heinz-Juergen; Bioorganic and Medicinal Chemistry; vol. 9; nb. 7; (2001); p. 1879 - 1885, View in Reaxys Target Subunit Synonyms

tyrosinase

Compound name

L-DOPA

Compound role

SUB

137 of 200 Bioassay Category Bioassay Details

In Vitro (Efficacy) Minimum Inhibitory concentration of the compound against Streptococcus sobrinus 6715 strain

Biological Species/NCBI Streptococcus sobrinus 6715 ID Substance RN

784514View in Reaxys

Measurement Parameter

MIC

Unit

µM

Qualitative value

Quantitative value

500

Measurement pX

Koo, Hyun; Rosalen, Pedro L.; Cury, Jaime A.; Park, Yong K.; Bowen, William H.; Antimicrobial Agents and Chemotherapy; vol. 46; nb. 5; (2002); p. 1302 - 1309, View in Reaxys Measurement Object 138 of 200 Bioassay Category Bioassay Details

Minimum Inhibitory Concentration Toxicity/Safety Pharmacology Toxicity was measured as population growth impairment to Tetrahymena pyriformis

Biological Species/NCBI Tetrahymena pyriformis ID Substance RN

784514View in Reaxys

Measurement Parameter

Qualitative

Qualitative value

Not Published

109/130

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Cronin; Schultz; Chemical Research in Toxicology; vol. 14; nb. 9; (2001); p. 1284 - 1295, View in Reaxys 139 of 200 Substance Action on Target

Inhibitor

Bioassay Category

In Vitro (Efficacy)

Bioassay Details

Inhibitory concentration of the compound against 1 umol/L fMLP-induced superoxide production in human neutrophils in the presence of 0.5 mg/ml ferryicytochrome c by continuous spectrophotometric assay

Biological Species/NCBI Human ID Cells/Cell Lines

Neutrophil

Substance RN

784514View in Reaxys

Measurement Parameter

IC50

Unit

µM

Qualitative value

Quantitative value

100

Measurement pX

Chen, Jih-Jung; Chen, Po-Hou; Liao, Chang-Hui; Huang, Shi-Yu; Chen, Ih-Sheng; Journal of Natural Products; vol. 70; nb. 9; (2007); p. 1444 - 1448, View in Reaxys Compound name

Ferryicytochrome c (0.5 mg/ml)

Compound role

COM

140 of 200 Substance Effect

Antiplasmodic

Bioassay Category

In Vitro (Efficacy)

Bioassay Details

In vitro inhibitory concentration of compound against PLASMODIUM FALCIPARUM CHLOROQUINE-SUSCEPTIBLE 3D7 cell growth was determined

Biological Species/NCBI chloroquine susceptible Plasmodium falciparum 3D7 ID Substance RN

784514View in Reaxys

Measurement Parameter

IC50

Unit

µg/mL

Qualitative value

Quantitative value

Measurement pX

4.15

Magadula, Joseph J.; Erasto, Paul; Natural Product Reports; vol. 26; nb. 12; (2009); p. 1535 - 1554, View in Reaxys Measurement Object 141 of 200 Substance Effect

Cell growth Antimalarial

Bioassay Category

In Vitro (Efficacy)

Bioassay Details

Inhibitory concentration of compound against PLASMODIUM FALCIPARUM CHLOROQUINE-RESISTANT FCM29 cell growth was determined

Biological Species/NCBI chloroquine resistant Plasmodium falciparum FcM29 ID Substance RN

784514View in Reaxys

Measurement Parameter

IC50

Unit

µg/mL

Qualitative value

110/130

2017-10-08 12:35:19

Quantitative value

21.4

Measurement pX

3.93

Magadula, Joseph J.; Erasto, Paul; Natural Product Reports; vol. 26; nb. 12; (2009); p. 1535 - 1554, View in Reaxys Measurement Object 142 of 200 Substance Action on Target

Cell growth Inhibitor

Bioassay Category

In Vitro (Efficacy)

Bioassay Details

Inhibitory concentration of the compound against DPPH radical scavenging at 120 min by DPPH assay

Substance RN

784514View in Reaxys

Measurement Parameter

IC50

Unit

µM

Qualitative value

Quantitative value

100

Deviation

Measurement pX

Lee, Choon Young; Sharma, Ajit; Cheong, Jae Eun; Nelson, Julie L.; Bioorganic and Medicinal Chemistry Letters; vol. 19; nb. 22; (2009); p. 6326 - 6330, View in Reaxys 143 of 200 Bioassay Category Bioassay Details

Toxicity/Safety Pharmacology 50% inhibitory growth concentration for Tetrahymena pyriformis;Acute toxicity

Biological Species/NCBI Tetrahymena pyriformis ID Substance RN

784514View in Reaxys

Measurement Parameter

Qualitative

Qualitative value

Not Published

Dimitrov, Sabcho; Koleva, Yana; Schultz, T. Wayne; Walker, John D.; Mekenyan, Ovanes; Environmental Toxicology and Chemistry; vol. 23; nb. 2; (2004); p. 463 - 470, View in Reaxys 144 of 200 Substance Action on Target

Inhibitor

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Details

Growth inhibitory activity against Tetrahymena pyriformis

Biological Species/NCBI Tetrahymena pyriformis ID Substance RN

784514View in Reaxys

Measurement Parameter

Qualitative

Qualitative value

Not Published

Cronin, Mark T.D.; Aptula, Aynur O.; Duffy, Judith C.; Netzeva, Tatiana I.; Rowe, Philip H.; Valkova, Iva V.; Schultz, T. Wayne; Chemosphere; vol. 49; nb. 10; (2002); p. 1201 - 1221, View in Reaxys 145 of 200 Bioassay Category Bioassay Details

In Vitro (Efficacy) In vitro inhibitory activity against caspase mediated apoptosis in mouse leukemia L1210 cells was determined

Biological Species/NCBI Mus musculus ID Cells/Cell Lines

L-1210 cell line

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Substance RN

784514View in Reaxys

Measurement Parameter

ID50

Quantitative value

2.9

Nandi, Sisir; Vracko, Marjan; Bagchi, Manish C.; Chemical Biology and Drug Design; vol. 70; nb. 5; (2007); p. 424 - 436, View in Reaxys Measurement Object 146 of 200 Bioassay Category Bioassay Details

caspase mediated apoptosis In Vitro (Efficacy) Growth inhibition of mouse leukemia L1210 cells was determined

Biological Species/NCBI Mus musculus ID Cells/Cell Lines

L-1210 cell line

Substance RN

784514View in Reaxys

Measurement Parameter

ID50

Quantitative value

3.1

Nandi, Sisir; Vracko, Marjan; Bagchi, Manish C.; Chemical Biology and Drug Design; vol. 70; nb. 5; (2007); p. 424 - 436, View in Reaxys Measurement Object 147 of 200 Substance Effect

Growth inhibition Cytotoxic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Cells/Cell Lines

MCG-803

Substance RN

784514View in Reaxys

Substance Name

21-page 386, paragraph 6

Measurement Parameter

IC50

Unit

µmol

Qualitative value

Quantitative value

100

Zhu, Jia-Xian; Qin, Jiang-Jiang; Zhang, Fei; Chang, Rui-Jie; Ren, Jie; Cheng, Xiang-Rong; Zeng, Qi; Jin, HuiZi; Zhang, Wei-Dong; Chemistry of Natural Compounds; vol. 49; nb. 2; (2013); p. 383 - 387; Khim. Prir. Soedin.; vol. 49; nb. 2; (2013); p. 324 - 327,4, View in Reaxys 148 of 200 Substance Effect

Cytotoxic

Bioassay Category

Toxicity/Safety Pharmacology

Bioassay Name

Cell/tumor cell: proliferation/viability/growth

Cells/Cell Lines

SKOV3

Substance RN

784514View in Reaxys

Substance Name

21-page 386, paragraph 6

Measurement Parameter

IC50

Unit

µmol

Qualitative value

Quantitative value

100

112/130

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149 of 200 Substance Effect

Cytotoxic

Bioassay Category

Toxicity/Safety Pharmacology

Cells/Cell Lines

Hep G2-2.2.15

Substance RN

784514View in Reaxys

Substance Name

4-hydroxy-3,5-dimethoxybenzaldehyde

Measurement Parameter

CC50

Unit

μM

Quantitative value

1504.7

Measurement pX

2.82

Anti-HBV

Bioassay Category

In Vitro (Efficacy)

Cells/Cell Lines

Hep G2-2.2.15

Substance RN

784514View in Reaxys

Substance Name

4-hydroxy-3,5-dimethoxybenzaldehyde

Measurement Parameter

IC50

Unit

μM

Quantitative value

2343.88

Measurement pX

2.63

Anti-HBV

Bioassay Category

In Vitro (Efficacy)

Cells/Cell Lines

Hep G2-2.2.15

Substance RN

784514View in Reaxys

Substance Name

4-hydroxy-3,5-dimethoxybenzaldehyde

Measurement Parameter

IC50

Unit

μM

Quantitative value

3717.16

Measurement pX

2.43

Anti-HBV

Bioassay Category

In Vitro (Efficacy)

Cells/Cell Lines

Hep G2-2.2.15

Substance RN

784514View in Reaxys

Substance Name

4-hydroxy-3,5-dimethoxybenzaldehyde

Measurement Parameter

IC50

Unit

μM

Quantitative value

763.22

113/130

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Measurement pX

3.12

DNA REPLICATION Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

% Inhibition

Unit

Quantitative value

Measurement pX

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys 154 of 200 Bioassay Category

Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

% Inhibition

Unit

Quantitative value

Measurement pX

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys 155 of 200 Bioassay Category

Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

% Inhibition

Unit

Quantitative value

Measurement pX

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys 156 of 200 Bioassay Category

Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

114/130

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Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

% Inhibition

Unit

Quantitative value

Measurement pX

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys 157 of 200 Bioassay Category

Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

Unit

Quantitative value

42.1

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 158 of 200 Bioassay Category

Oleic acid (C18:1) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

0.5 g/l

Measurement Parameter

Unit

Quantitative value

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 159 of 200 Bioassay Category

Oleic acid (C18:1) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.5 g/l

Measurement Parameter

Unit

Quantitative value

47.2

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys

115/130

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Measurement Object 160 of 200 Bioassay Category

Oleic acid (C18:1) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

Unit

Quantitative value

49.2

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 161 of 200 Bioassay Category

Oleic acid (C18:1) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.5 g/l

Measurement Parameter

Unit

Quantitative value

6.8

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 162 of 200 Bioassay Category

Fatty acid (C18:2) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

0.5 g/l

Measurement Parameter

Unit

Quantitative value

7.8

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 163 of 200 Bioassay Category

Fatty acid (C18:2) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

116/130

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Measurement Parameter

Unit

Quantitative value

7.9

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 164 of 200 Bioassay Category

Fatty acid (C18:2) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

Unit

Quantitative value

8.8

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 165 of 200 Bioassay Category

Fatty acid (C18:2) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.5 g/l

Measurement Parameter

Unit

Quantitative value

23.4

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 166 of 200 Bioassay Category

Fatty acid (C16:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

0.5 g/l

Measurement Parameter

Unit

Quantitative value

24.3

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 167 of 200 Bioassay Category

Fatty acid (C16:0) Toxicity/Safety Pharmacology

117/130

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Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

Unit

Quantitative value

24.6

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 168 of 200 Bioassay Category

Fatty acid (C16:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

Unit

Quantitative value

25.1

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 169 of 200 Bioassay Category

Fatty acid (C16:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

Unit

Quantitative value

14.9

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 170 of 200 Bioassay Category

Fatty acid (C18:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

Unit

118/130

2017-10-08 12:35:19

Quantitative value

15.8

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 171 of 200 Bioassay Category

Fatty acid (C18:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

0.5 g/l

Measurement Parameter

Unit

Quantitative value

16.3

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 172 of 200 Bioassay Category

Fatty acid (C18:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.5 g/l

Measurement Parameter

Unit

Quantitative value

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 173 of 200 Bioassay Category

Fatty acid (C18:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

Unit

Quantitative value

45.2

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 174 of 200 Bioassay Category

Oleic acid (C18:1) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

119/130

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Substance Name

syringaldehyde

Substance Dose

1.5 g/l

Measurement Parameter

Unit

Quantitative value

46.6

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 175 of 200 Bioassay Category

Oleic acid (C18:1) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

0.5 g/l

Measurement Parameter

Unit

Quantitative value

47.1

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 176 of 200 Bioassay Category

Oleic acid (C18:1) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

Unit

Quantitative value

48.3

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 177 of 200 Bioassay Category

Oleic acid (C18:1) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.5 g/l

Measurement Parameter

Unit

Quantitative value

10.2

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys

120/130

2017-10-08 12:35:19

Measurement Object 178 of 200 Bioassay Category

Fatty acid (C18:2) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

0.5 g/l

Measurement Parameter

Unit

Quantitative value

11.6

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 179 of 200 Bioassay Category

Fatty acid (C18:2) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

Unit

Quantitative value

12.7

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 180 of 200 Bioassay Category

Fatty acid (C18:2) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

Unit

Quantitative value

9.9

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 181 of 200 Bioassay Category

Fatty acid (C18:2) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

121/130

2017-10-08 12:35:19

Measurement Parameter

Unit

Quantitative value

24.8

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 182 of 200 Bioassay Category

Fatty acid (C16:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

Unit

Quantitative value

25.2

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 183 of 200 Bioassay Category

Fatty acid (C16:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

0.5 g/l

Measurement Parameter

Unit

Quantitative value

25.7

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 184 of 200 Bioassay Category

Fatty acid (C16:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.5 g/l

Measurement Parameter

Unit

Quantitative value

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 185 of 200 Bioassay Category

Fatty acid (C16:0) Toxicity/Safety Pharmacology

122/130

2017-10-08 12:35:19

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

0.5 g/l

Measurement Parameter

Unit

Quantitative value

15.8

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 186 of 200 Bioassay Category

Fatty acid (C18:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

2.0 g/l

Measurement Parameter

Unit

Quantitative value

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 187 of 200 Bioassay Category

Fatty acid (C18:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.5 g/l

Measurement Parameter

Unit

Quantitative value

16.4

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 188 of 200 Bioassay Category

Fatty acid (C18:0) Toxicity/Safety Pharmacology

Biological Species/NCBI Cryptococcus curvatus ATCC 20509 ID Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

1.0 g/l

Measurement Parameter

Unit

123/130

2017-10-08 12:35:19

Quantitative value

19.2

Yu, Xiaochen; Zeng, Jijiao; Zheng, Yubin; Chen, Shulin; Process Biochemistry; vol. 49; nb. 3; (2014); p. 457 465, View in Reaxys Measurement Object 189 of 200 Substance Effect

Fatty acid (C18:0) Antineoplastic

Bioassay Category

Toxicity/Safety Pharmacology

Cells/Cell Lines

SGC 7901

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Measurement Parameter

IC50

Unit

μM

Qualitative value

Quantitative value

Measurement pX

4.52

Chen, Xiu-Juan; Mei, Wen-Li; Cai, Cai-Hong; Guo, Zhi-Kai; Song, Xi-Qiang; Dai, Hao-Fu; Phytochemistry Letters; vol. 9; nb. 1; (2014); p. 107 - 112, View in Reaxys 190 of 200 Substance Effect

Antineoplastic

Bioassay Category

Toxicity/Safety Pharmacology

Cells/Cell Lines

BEL7402

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Measurement Parameter

IC50

Unit

μM

Qualitative value

Quantitative value

Measurement pX

4.52

Chen, Xiu-Juan; Mei, Wen-Li; Cai, Cai-Hong; Guo, Zhi-Kai; Song, Xi-Qiang; Dai, Hao-Fu; Phytochemistry Letters; vol. 9; nb. 1; (2014); p. 107 - 112, View in Reaxys 191 of 200 Substance Effect

Antineoplastic

Bioassay Category

Toxicity/Safety Pharmacology

Cells/Cell Lines

K 562

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Measurement Parameter

IC50

Unit

μM

Qualitative value

Quantitative value

Measurement pX

4.52

Chen, Xiu-Juan; Mei, Wen-Li; Cai, Cai-Hong; Guo, Zhi-Kai; Song, Xi-Qiang; Dai, Hao-Fu; Phytochemistry Letters; vol. 9; nb. 1; (2014); p. 107 - 112, View in Reaxys 192 of 200 Substance Effect Bioassay Category

Antifungal In Vitro (Efficacy)

124/130

2017-10-08 12:35:19

Biological Species/NCBI Saccharomyces cerevisiae ID Substance RN

784514View in Reaxys

Substance Name

3,5-dimethoxy-4-hydroxybenzaldehyde

Substance Dose

1-5 mM

Measurement Parameter

Growth score

Unit

no unit

Quantitative value

Kim, Jong H.; Chan, Kathleen L.; Mahoney, Noreen; International Journal of Molecular Sciences; vol. 16; nb. 11; (2015); p. 26850 - 26870, View in Reaxys Measurement Object 193 of 200 Substance Effect Bioassay Category

Score (0=no colonies visible in any dilutions; 1=10e6 cells visible; 2=undiluted 10e6 and 10e5 cells visible; 6=visible from all dilution spots Antifungal In Vitro (Efficacy)

Biological Species/NCBI Saccharomyces cerevisiae ID Substance RN

784514View in Reaxys

Substance Name

3,5-dimethoxy-4-hydroxybenzaldehyde

Substance Dose

1-5 mM

Measurement Parameter

Growth score

Unit

no unit

Quantitative value

Kim, Jong H.; Chan, Kathleen L.; Mahoney, Noreen; International Journal of Molecular Sciences; vol. 16; nb. 11; (2015); p. 26850 - 26870, View in Reaxys Measurement Object 194 of 200 Substance Effect Bioassay Category

Score (0=no colonies visible in any dilutions; 1=10e6 cells visible; 2=undiluted 10e6 and 10e5 cells visible; 6=visible from all dilution spots Antifungal In Vitro (Efficacy)

Biological Species/NCBI Saccharomyces cerevisiae BY4741 ID Substance RN

784514View in Reaxys

Substance Name

3,5-dimethoxy-4-hydroxybenzaldehyde

Substance Dose

1-5 mM

Measurement Parameter

Growth score

Unit

no unit

Quantitative value

Kim, Jong H.; Chan, Kathleen L.; Mahoney, Noreen; International Journal of Molecular Sciences; vol. 16; nb. 11; (2015); p. 26850 - 26870, View in Reaxys Measurement Object 195 of 200 Substance Effect

Score (0=no colonies visible in any dilutions; 1=10e6 cells visible; 2=undiluted 10e6 and 10e5 cells visible; 6=visible from all dilution spots Antioxidant

Bioassay Category

In Vitro (Efficacy)

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

125/130

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Substance Dose

50 μmol/l

Measurement Parameter

Percent of control

Unit

Quantitative value

6.6

Inui, Takako; Okumura, Koharu; Matsui, Hiroo; Hosoya, Takahiro; Kumazawa, Shigenori; Food Chemistry; vol. 225; (2017); p. 69 - 76, View in Reaxys 196 of 200 Substance Effect

Antioxidant

Bioassay Category

In Vitro (Efficacy)

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

12.5 μmol/l

Measurement Parameter

Percent of control

Unit

Quantitative value

Inui, Takako; Okumura, Koharu; Matsui, Hiroo; Hosoya, Takahiro; Kumazawa, Shigenori; Food Chemistry; vol. 225; (2017); p. 69 - 76, View in Reaxys 197 of 200 Substance Effect

Antiinflammatory

Bioassay Category

In Vitro (Efficacy)

Cells/Cell Lines

J774.1

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

100 μmol/l

Measurement Parameter

Percent of control

Unit

Quantitative value

26.4

Inui, Takako; Okumura, Koharu; Matsui, Hiroo; Hosoya, Takahiro; Kumazawa, Shigenori; Food Chemistry; vol. 225; (2017); p. 69 - 76, View in Reaxys Compound RN

8187061

Compound name

lipopolysaccharide

Compound role

IND

198 of 200 Substance Effect

Antiinflammatory

Bioassay Category

In Vitro (Efficacy)

Cells/Cell Lines

J774.1

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

10 μmol/l

Measurement Parameter

Percent of control

Unit

Quantitative value

3.6

Inui, Takako; Okumura, Koharu; Matsui, Hiroo; Hosoya, Takahiro; Kumazawa, Shigenori; Food Chemistry; vol. 225; (2017); p. 69 - 76, View in Reaxys Compound RN

8187061

126/130

2017-10-08 12:35:19

Compound name

lipopolysaccharide

Compound role

IND

199 of 200 Substance Effect

Antiadipogenic

Bioassay Category

In Vitro (Efficacy)

Cells/Cell Lines

3T3 L1

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

10 μmol/l

Measurement Parameter

Percent of control

Unit

Quantitative value

Inui, Takako; Okumura, Koharu; Matsui, Hiroo; Hosoya, Takahiro; Kumazawa, Shigenori; Food Chemistry; vol. 225; (2017); p. 69 - 76, View in Reaxys 200 of 200 Substance Effect

Antiadipogenic

Bioassay Category

In Vitro (Efficacy)

Cells/Cell Lines

3T3 L1

Substance RN

784514View in Reaxys

Substance Name

syringaldehyde

Substance Dose

100 μmol/l

Measurement Parameter

Percent of control

Unit

Quantitative value

Inui, Takako; Okumura, Koharu; Matsui, Hiroo; Hosoya, Takahiro; Kumazawa, Shigenori; Food Chemistry; vol. 225; (2017); p. 69 - 76, View in Reaxys

Reaxys ID 9050631 View in Reaxys

2/7 Linear Structure Formula: C9H8D2O4 Molecular Formula: C9H10O4 Molecular Weight: 184.16 Type of Substance: isocyclic InChI Key: KCDXJAYRVLXPFO-NMQOAUCRSA-N Note:

O 2H

O OH

Druglikeness (1) 1 of 1

LogP

0.874

H Bond Donors

H Bond Acceptors

Rotatable Bonds

TPSA

55.76

Lipinski Number

Veber Number

127/130

2017-10-08 12:35:19

Reaxys ID 2282912 View in Reaxys

H 14C

3/7 Chemical Name: Syringoaldehyd-(carbonyl-14C); Syringaaldehyd-<carbonyl-14C>; Syringaaldehyd-(carbonyl-14C) Linear Structure Formula: C8 (14)CH10O4 Molecular Formula: C9H10O4 Molecular Weight: 184.165 Type of Substance: isocyclic InChI Key: KCDXJAYRVLXPFO-RHRFEJLCSA-N Note:

O HO

Druglikeness (1) 1 of 1

LogP

0.874

H Bond Donors

H Bond Acceptors

Rotatable Bonds

TPSA

55.76

Lipinski Number

Veber Number

Reaxys ID 10535305 View in Reaxys

4/7 Chemical Name: [Me-14C1]syringaldehyde Linear Structure Formula: C8 (14)CH10O4 Molecular Formula: C9H10O4 Molecular Weight: 184.165 Type of Substance: isocyclic InChI Key: KCDXJAYRVLXPFO-NJFSPNSNSA-N Note:

O H 14 3 C O HO

Substance Label (1) Label References 14

Kota, Parvathi; Guo, Dianjing; Zubieta, Chloe; Noel, Joe; Dixon, Richard A.; Phytochemistry; vol. 65; nb. 7; (2004); p. 837 - 846, View in Reaxys

Druglikeness (1) 1 of 1

LogP

0.874

H Bond Donors

H Bond Acceptors

Rotatable Bonds

TPSA

55.76

Lipinski Number

Veber Number

Reaxys ID 26715523 View in Reaxys

5/7 CAS Registry Number: 1574215-65-8 Linear Structure Formula: C9H10O3 (18)O Molecular Formula: C9H10O4 Molecular Weight: 184.177 InChI Key: KCDXJAYRVLXPFO-HRVHXUPCSA-N Note:

18O

O OH

Substance Label (1) Label References

128/130

2017-10-08 12:35:19

2aa

Jiang, Jian-An; Chen, Cheng; Huang, Jian-Gang; Liu, Hong-Wei; Cao, Song; Ji, Ya-Fei; Green Chemistry; vol. 16; nb. 3; (2014); p. 1248 - 1254, View in Reaxys

Druglikeness (1) 1 of 1

LogP

0.874

H Bond Donors

H Bond Acceptors

Rotatable Bonds

TPSA

55.76

Lipinski Number

Veber Number

Crystal Property Description (1) Colour & Other Location Properties yellow

References

supporting information

Jiang, Jian-An; Chen, Cheng; Huang, Jian-Gang; Liu, Hong-Wei; Cao, Song; Ji, YaFei; Green Chemistry; vol. 16; nb. 3; (2014); p. 1248 - 1254, View in Reaxys

Mass Spectrometry (1) Description (Mass Location Spectrometry) electron impact (EI); high resolution mass spectrometry (HRMS); time-of-flight mass spectra (TOFMS); spectrum

References

supporting information

Jiang, Jian-An; Chen, Cheng; Huang, Jian-Gang; Liu, Hong-Wei; Cao, Song; Ji, YaFei; Green Chemistry; vol. 16; nb. 3; (2014); p. 1248 - 1254, View in Reaxys

Reaxys ID 11274354 View in Reaxys

6/7 CAS Registry Number: 934634-11-4 Chemical Name: [3-OC(2)H3]syringaldehyde Linear Structure Formula: C9H7 (2)H3O4 Molecular Formula: C9H10O4 Molecular Weight: 185.152 InChI Key: KCDXJAYRVLXPFO-FIBGUPNXSA-N Note:

O OH

Substance Label (1) Label References 33c

Sakakibara, Norikazu; Nakatsubo, Tomoyuki; Suzuki, Shiro; Shibata, Daisuke; Shimada, Mikio; Umezawa, Toshiaki; Organic and Biomolecular Chemistry; vol. 5; nb. 5; (2007); p. 802 - 815, View in Reaxys

Druglikeness (1) 1 of 1

LogP

0.874

H Bond Donors

H Bond Acceptors

Rotatable Bonds

TPSA

55.76

Lipinski Number

Veber Number

129/130

2017-10-08 12:35:19

Reaxys ID 9263284 View in Reaxys

7/7 Chemical Name: syringaldehyde-[3,5-OCD3] Linear Structure Formula: C9H4 (2)H6O4 Molecular Formula: C9H10O4 Molecular Weight: 188.128 Type of Substance: isocyclic InChI Key: KCDXJAYRVLXPFO-WFGJKAKNSA-N Note:

2H 2H

Substance Label (1) Label References 14s

Sakakibara, Norikazu; Suzuki, Shiro; Umezawa, Toshiaki; Shimada, Mikio; Organic and biomolecular chemistry; vol. 1; nb. 14; (2003); p. 2474 - 2485, View in Reaxys

Druglikeness (1) 1 of 1

LogP

0.874

H Bond Donors

H Bond Acceptors

Rotatable Bonds

TPSA

55.76

Lipinski Number

Veber Number

130/130

2017-10-08 12:35:19