2-Amino-1-phenylpropan-1-ol (PPA) to 2-Amino-1-phenylpropan-1-one (CAT)

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Query Query HO

1. Query

H 2N

Results

Date

5 reactions in Reaxys

2017-11-28 21h:03m:03s (EST)

O

H 2N

Search as: As drawn, No salts, No mixtures

Copyright © 2017 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.

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2017-11-28 21:06:10


O

OH

H

H 2N

H 2N H

H

Rx-ID: 29581122 View in Reaxys 1/5 Yield

Conditions & References With potassium permanganate Krizevski, Raz; Bar, Einat; Shalit, Or; Sitrit, Yaron; Ben-Shabat, Shimon; Lewinsohn, Efraim; Phytochemistry; vol. 71; nb. 8-9; (2010); p. 895 - 903 View in Reaxys With potassium permanganate Mohr, Stefan; Taschwer, Magdalena; Schmid, Martin G.; Chirality; vol. 24; nb. 6; (2012); p. 486 - 492 View in Reaxys

H 2N

H

HO

H

O H 2N H

Rx-ID: 33699785 View in Reaxys 2/5 Yield

Conditions & References With potassium permanganate Mohr, Stefan; Taschwer, Magdalena; Schmid, Martin G.; Chirality; vol. 24; nb. 6; (2012); p. 486 - 492 View in Reaxys

HO

O

H 2N

H 2N

Rx-ID: 4417068 View in Reaxys 3/5 Yield

Conditions & References

89 %

With trifluoroacetic acid, 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dimethyl sulfoxide, Time= 3.5h, Ambient temperature Frigerio, Marco; Santagostino, Marco; Sputore, Simona; Palmisano, Giovanni; Journal of Organic Chemistry; vol. 60; nb. 22; (1995); p. 7272 - 7276 View in Reaxys

HO O

OH H 2N

O H 2N

Cl

H

H

Rx-ID: 20540861 View in Reaxys 4/5 Yield

Conditions & References Reaction Steps: 3 1: 92 percent / toluene / 48 h / Heating 2: 83 percent / CrO3, pyridine / CH2Cl2 / 0.25 h 3: 72 percent / 20percent HCl / 5 h / 40 °C With pyridine, chromium(VI) oxide, hydrogenchloride in dichloromethane, toluene Berrang; Lewin; Carroll; Journal of Organic Chemistry; vol. 47; nb. 13; (1982); p. 2643 - 2647 View in Reaxys

Copyright © 2017 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.

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2017-11-28 21:06:10


O

HO O

OH H 2N

H 2N

Cl

H

Rx-ID: 20540864 View in Reaxys 5/5 Yield

Conditions & References Reaction Steps: 3 1: 96 percent / toluene / 60 h / Heating 2: 83 percent / CrO3, pyridine / CH2Cl2 / 0.25 h 3: 60 percent / 6 N HCl / 40 °C With pyridine, chromium(VI) oxide, hydrogenchloride in dichloromethane, toluene Berrang; Lewin; Carroll; Journal of Organic Chemistry; vol. 47; nb. 13; (1982); p. 2643 - 2647 View in Reaxys

Copyright © 2017 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.

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2017-11-28 21:06:10


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