2-Amino-1-phenylpropan-1-ol (PPA) [DLNKOYKMWOXYQA-UHFFFAOYSA-N] to 1-Phenylpropan-2-amine (A

Page 1

Bioactivities (1549)

Yield

Reactions (7)

Substances (10)

Targets (114)

Conditions

Citations (4)

References

1

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Multi-step reaction with 2 steps 1: hydrochlorid acid / methanol / 0.5 h / 760.05 Torr 2: palladium 10 on activated carbon; hydrogen / methanol / 20 h / 20 °C / 3102.97 Torr View Scheme

Rx-ID: 41227784

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Lalwani, Komal G.; Sudalai, Arumugam

Tetrahedron Letters, 2015 , vol. 56, # 46 p. 6488 - 6490 Title/Abstract Full Text View citing articles Show Details

2

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Rx-ID: 13205671

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Multi-step reaction with 3 steps 1: 95 percent / pyridine / 24 h / 20 °C 2: 55 percent / H2; aq. perchloric acid; glacial AcOH / Pd/BaSO4 / 4.5 h / 95 °C / atmospheric pressure 3: aq. H2SO4 / 40 h / Heating View Scheme

Fecik, Robert A.; Devasthale, Pratik; Pillai, Segaran; Keschavarz-Shokri, Ali; Shen, Linus; Mitscher, Lester A.

Journal of Medicinal Chemistry, 2005 , vol. 48, # 4 p. 1229 - 1236 Title/Abstract Full Text View citing articles Show Details

3

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Multi-step reaction with 3 steps 1: 86 percent / pyridine / 24 h / 20 °C 2: 71 percent / H2; aq. perchloric acid; glacial AcOH / Pd/BaSO4 / 4.5 h / 95 °C / atmospheric pressure 3: H2SO4; water / 40 h / Heating View Scheme

Rx-ID: 13207694

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Fecik, Robert A.; Devasthale, Pratik; Pillai, Segaran; Keschavarz-Shokri, Ali; Shen, Linus; Mitscher, Lester A.

Journal of Medicinal Chemistry, 2005 , vol. 48, # 4 p. 1229 - 1236 Title/Abstract Full Text View citing articles Show Details

4

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5

Stage #1: With acetic anhydride; acetic acid

2 h; Stage #2: With hydrogen; palladium 10 on activated carbon

22 h; Product distribution / selectivity;

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Rx-ID: 23249684

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BOEHRINGER INGELHEIM CHEMICALS INC

Patent: JP2005/507936 A, 2005 ; Location in patent: Page/Page column 16-17 ; Title/Abstract Full Text Show Details


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With phosphorus; hydrogen iodide

T=40 - 100°C; 2 - 22 h;

Rx-ID: 23251463

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BOEHRINGER INGELHEIM CHEMICALS INC

Patent: JP2005/507936 A, 2005 ; Location in patent: Page/Page column 13 ; Title/Abstract Full Text Show Details

6

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With hydrogenchloride; hydrogen; phosphorus pentabromide; palladium on activated charcoal

Yield given. Multistep reaction;

Rx-ID: 2103532

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Buckley, Thomas F.; Rapoport, Henry

Journal of the American Chemical Society, 1981 , vol. 103, # 20 p. 6157 - 6163 Title/Abstract Full Text View citing articles Show Details

7

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With hydrogenchloride; hydrogen; phosphorus pentabromide; palladium on activated charcoal

Yield given. Multistep reaction;

Rx-ID: 2103533

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Buckley, Thomas F.; Rapoport, Henry

Journal of the American Chemical Society, 1981 , vol. 103, # 20 p. 6157 - 6163 Title/Abstract Full Text View citing articles Show Details


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