[3] 5-('GH')-3-((4-('GH')piperazin-1-yl)methyl)-1H-indole by Asch

Query Query N

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181 substances in Reaxys

2017-11-11 00h:15m:26s (EST)

1. Query

Search as: As drawn, No mixtures, No isotopes, No charges, No radicals

1/41

2017-11-11 00:19:22

Reaxys ID 9130285 View in Reaxys

1/181 Chemical Name: N-piperazinyl-3-indolylmethylamine; 3-(4H-piperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C13H17N3 Molecular Formula: C13H17N3 Molecular Weight: 215.298 Type of Substance: heterocyclic InChI Key: ZTNAIHGOFCMOPJ-UHFFFAOYSA-N Note:

Reaxys ID 885083 View in Reaxys

2/181 CAS Registry Number: 5444-91-7 Chemical Name: 3-[(4-methyl-1-piperazinyl)methyl]-1H-indole; N-methyl-N-piperazinyl-3-indolylmethylamine; 3-(4-methyl-piperazin-1-ylmethyl)-indole; 3-(4-methylpiperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C14H19N3 Molecular Formula: C14H19N3 Molecular Weight: 229.325 Type of Substance: heterocyclic InChI Key: YLWXBMKGZWALKM-UHFFFAOYSA-N Note:

Reaxys ID 616281 View in Reaxys

3/181 CAS Registry Number: 58433-77-5 Chemical Name: 4-indol-3-ylmethyl-piperazin-1-ylamine; 3-(4aminopiperazin-1-yl)-methylindole; 3-(4-aminopiperazin-1yl)methylindole Linear Structure Formula: C13H18N4 Molecular Formula: C13H18N4 Molecular Weight: 230.313 Type of Substance: heterocyclic InChI Key: WAEYKEUXVHQOSI-UHFFFAOYSA-N Note:

NH 2

Reaxys ID 6145388 View in Reaxys

4/181 Chemical Name: 5-fluoro-3-<(4-piperazinyl)methyl>-1H-indole Linear Structure Formula: C13H16FN3 Molecular Formula: C13H16FN3 Molecular Weight: 233.289 Type of Substance: heterocyclic InChI Key: PFOFHPUVOGVDPE-UHFFFAOYSA-N Note:

NH F N

Reaxys ID 31231723 View in Reaxys

5/181

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Chemical Name: N-ethyl-N-piperazinyl-3-indolylmethylamine Linear Structure Formula: C15H21N3 Molecular Formula: C15H21N3 Molecular Weight: 243.352 InChI Key: UQSASCFTSPWPHK-UHFFFAOYSA-N Note:

Reaxys ID 618828 View in Reaxys

6/181 CAS Registry Number: 58433-76-4 Chemical Name: 3-(4-nitroso-piperazin-1-ylmethyl)-indole; 3(4-nitrosopiperazin-1-yl)methylindole Linear Structure Formula: C13H16N4O Molecular Formula: C13H16N4O Molecular Weight: 244.296 Type of Substance: heterocyclic InChI Key: ZQSFMPBEDRJMOD-UHFFFAOYSA-N Note:

N O

Reaxys ID 31558193 View in Reaxys

7/181 Chemical Name: 3-((4-methylpiperazin-1-yl)methyl)-1H-indol-5-amine Linear Structure Formula: C14H20N4 Molecular Formula: C14H20N4 Molecular Weight: 244.34 InChI Key: NSARELUBFYUJHP-UHFFFAOYSA-N Note:

H 2N

NH N

Reaxys ID 21044275 View in Reaxys

8/181 CAS Registry Number: 1258296-97-7 Linear Structure Formula: C14H18FN3 Molecular Formula: C14H18FN3 Molecular Weight: 247.315 InChI Key: AWTPQMDTRQRTGS-UHFFFAOYSA-N Note:

F NH

Reaxys ID 27604335 View in Reaxys

9/181 Chemical Name: 3-{[4-(prop-2-yn-1-yl)piperazine-1-yl]methyl}-1H-indole Linear Structure Formula: C16H19N3 Molecular Formula: C16H19N3 Molecular Weight: 253.347 InChI Key: NWSUXYSNUGRBLB-UHFFFAOYSA-N Note:

N N

Reaxys ID 22705323 View in Reaxys

10/181

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CAS Registry Number: 101831-78-1 Chemical Name: 3-((4-methylpiperazin-1-yl)methyl)-1H-indole-5-carbonitrile; 3-[(4-methyl-1-piperazinyl)methyl]-1H-indole-5-carbonitrile Linear Structure Formula: C15H18N4 Molecular Formula: C15H18N4 Molecular Weight: 254.335 InChI Key: PVNWVAMWFWITOQ-UHFFFAOYSA-N Note:

N N

N H

Reaxys ID 22848088 View in Reaxys

11/181

CAS Registry Number: 1329045-35-3 Chemical Name: 3-[(4-acetylpiperazin-1-yl)methyl]-1H-indole; N-acetyl-N-piperazinyl-3-indolylmethylamine Linear Structure Formula: C15H19N3O Molecular Formula: C15H19N3O Molecular Weight: 257.335 InChI Key: UMKHJBUHGGCRGL-UHFFFAOYSA-N Note:

Reaxys ID 24294127 View in Reaxys

12/181 Linear Structure Formula: C14H19N5 Molecular Formula: C14H19N5 Molecular Weight: 257.338 InChI Key: JFHFDNKKARCSBD-UHFFFAOYSA-N Note:

NH NH 2

Reaxys ID 31231726 View in Reaxys

13/181 Chemical Name: N-isopropyl-N-piperazinyl-3-indolylmethylamine Linear Structure Formula: C16H23N3 Molecular Formula: C16H23N3 Molecular Weight: 257.379 InChI Key: NARZHCAAZXBIBS-UHFFFAOYSA-N Note:

Reaxys ID 31231725 View in Reaxys

14/181 Chemical Name: N-aminoethyl-N-piperazinyl-3-indolylmethylamine Linear Structure Formula: C15H22N4 Molecular Formula: C15H22N4 Molecular Weight: 258.366 InChI Key: JPWDEEQWKASEET-UHFFFAOYSA-N Note:

NH 2

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Reaxys ID 805970 View in Reaxys

15/181 CAS Registry Number: 17511-49-8 Chemical Name: N-(2″-hydroxyethyl)-N-piperazinyl-3-indolylmethylamine; 2-(4-indol-3-ylmethyl-piperazin-1-yl)-ethanol Linear Structure Formula: C15H21N3O Molecular Formula: C15H21N3O Molecular Weight: 259.351 Type of Substance: heterocyclic InChI Key: FLOIUBOBDOJASU-UHFFFAOYSA-N Note:

N OH

Reaxys ID 11950927 View in Reaxys

16/181 CAS Registry Number: 701205-15-4 Chemical Name: 5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole; 5-methoxy-3-(4-methylpiperazin-1-ylmethyl)-1Hindole; 5-Methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Linear Structure Formula: C15H21N3O Molecular Formula: C15H21N3O Molecular Weight: 259.351 InChI Key: LBQPYBWHUQEKBA-UHFFFAOYSA-N Note:

N O NH

Reaxys ID 11950929 View in Reaxys

17/181 CAS Registry Number: 701205-14-3 Chemical Name: 5-chloro-3-(4-methylpiperazin-1-ylmethyl)-1Hindole Linear Structure Formula: C14H18ClN3 Molecular Formula: C14H18ClN3 Molecular Weight: 263.77 InChI Key: GIMOMCJNROQVGI-UHFFFAOYSA-N Note:

N Cl NH

Reaxys ID 22705325 View in Reaxys

18/181 Chemical Name: 3-[(4-ethyl-1-piperazinyl)methyl]-5-methoxy-1H-indole Linear Structure Formula: C16H23N3O Molecular Formula: C16H23N3O Molecular Weight: 273.378 InChI Key: BRYRTQCGHXJGHS-UHFFFAOYSA-N Note:

N H

Reaxys ID 31231724 View in Reaxys

19/181 Chemical Name: N-(2″-methoxyethyl)-N-piperazinyl-3-indolylmethylamine Linear Structure Formula: C16H23N3O Molecular Formula: C16H23N3O Molecular Weight: 273.378 InChI Key: XMJDUTQRNGWTMC-UHFFFAOYSA-N Note:

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Reaxys ID 1592954 View in Reaxys

20/181 CAS Registry Number: 3414-71-9 Chemical Name: 3-((4-methylpiperazin-1-yl)methyl)-5-nitro-1Hindole; 3-(4-methyl-piperazin-1-ylmethyl)-5-nitro-indole; 5-nitro-3-(4-methylpiperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C14H18N4O2 Molecular Formula: C14H18N4O2 Molecular Weight: 274.323 Type of Substance: heterocyclic InChI Key: VGUWZCUCNQXGBU-UHFFFAOYSA-N Note:

NH O

N O

Reaxys ID 30912983 View in Reaxys

21/181 Linear Structure Formula: C15H21N3S Molecular Formula: C15H21N3S Molecular Weight: 275.418 InChI Key: UYKIBHJMUZMXNT-UHFFFAOYSA-N Note:

N S NH

Reaxys ID 22705326 View in Reaxys

22/181 Chemical Name: 3-((4-acetylpiperazin-1-yl)methyl)-1H-indole-5-carbonitrile; 3-[(4-acetyl-1-piperazinyl)methyl]-1H-indole-5-carbonitrile Linear Structure Formula: C16H18N4O Molecular Formula: C16H18N4O Molecular Weight: 282.345 InChI Key: QLHMZJMDKGISAT-UHFFFAOYSA-N Note:

N N

N O

N H

Reaxys ID 10274924 View in Reaxys

23/181 CAS Registry Number: 887477-38-5 Chemical Name: methyl 3-((4-methylpiperazin-1-yl)methyl)-1Hindole-5-carboxylate Linear Structure Formula: C16H21N3O2 Molecular Formula: C16H21N3O2 Molecular Weight: 287.362 Type of Substance: heterocyclic InChI Key: CEZSEVWPLODBQG-UHFFFAOYSA-N Note:

NH O O

Reaxys ID 25354053 View in Reaxys

24/181 Linear Structure Formula: C16H21N3O2 Molecular Formula: C16H21N3O2 Molecular Weight: 287.362 InChI Key: IWSHHUVABSTWOO-UHFFFAOYSA-N Note:

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Reaxys ID 30912980 View in Reaxys

25/181 Linear Structure Formula: C17H25N3O Molecular Formula: C17H25N3O Molecular Weight: 287.405 InChI Key: ZFDIFKWMGRIFIG-UHFFFAOYSA-N Note:

N O NH

Reaxys ID 891857 View in Reaxys

26/181 CAS Registry Number: 4281-72-5 Chemical Name: 3-((4-phenylpiperazin-1-yl)methyl)-1H-indole; 3-[(4-phenyl-1-piperazinyl)methyl]-1H-indole; 3-[(4-phenylpiperazin-1-yl)methyl]-1H-indole; 3-(4-phenylpiperazin-1-ylmethyl)-1H-indole; 3-(4-phenyl-piperazin-1-ylmethyl)-indole Linear Structure Formula: C19H21N3 Molecular Formula: C19H21N3 Molecular Weight: 291.396 Type of Substance: heterocyclic InChI Key: FDOZNCJWYJMHAG-UHFFFAOYSA-N Note:

Reaxys ID 11950976 View in Reaxys

27/181

CAS Registry Number: 300803-90-1 Chemical Name: 3-(4-(pyridin-2-yl)piperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C18H20N4 Molecular Formula: C18H20N4 Molecular Weight: 292.384 InChI Key: DGRLQDVYINGXQV-UHFFFAOYSA-N Note:

Reaxys ID 9714364 View in Reaxys

28/181 Chemical Name: 3-{[4-(pyrimidin-2-yl)piperazin-1-yl]methyl}-1H-indole; 3-[4-(2-pyrimidinyl)-piperazin-1-ylmethyl]-1H-indole Linear Structure Formula: C17H19N5 Molecular Formula: C17H19N5 Molecular Weight: 293.371 Type of Substance: heterocyclic InChI Key: GKKBEFXMNBECNL-UHFFFAOYSA-N Note:

N N N

Reaxys ID 825069 View in Reaxys

29/181

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CAS Registry Number: 17511-51-2 Chemical Name: 1-acetoxy-2-(4-indol-3-ylmethyl-piperazin-1yl)-ethane Linear Structure Formula: C17H23N3O2 Molecular Formula: C17H23N3O2 Molecular Weight: 301.389 Type of Substance: heterocyclic InChI Key: SGVVVFMPLMXOMY-UHFFFAOYSA-N Note:

N O O

Reaxys ID 823750 View in Reaxys

30/181 CAS Registry Number: 17511-50-1 Chemical Name: 3-(4-benzyl-piperazin-1-ylmethyl)-indole Linear Structure Formula: C20H23N3 Molecular Formula: C20H23N3 Molecular Weight: 305.423 Type of Substance: heterocyclic InChI Key: YHZKIEWEQQRAHY-UHFFFAOYSA-N Note:

Reaxys ID 22848089 View in Reaxys

31/181 CAS Registry Number: 414879-27-9 Chemical Name: 3-{[4-(2-methylphenyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C20H23N3 Molecular Formula: C20H23N3 Molecular Weight: 305.423 InChI Key: YQZHTUZDSCIWGT-UHFFFAOYSA-N Note:

Reaxys ID 22848090 View in Reaxys

32/181 CAS Registry Number: 1403574-74-2 Chemical Name: 3-{[4-(4-methylphenyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C20H23N3 Molecular Formula: C20H23N3 Molecular Weight: 305.423 InChI Key: BCJGEKQHRKDXCR-UHFFFAOYSA-N Note:

Reaxys ID 11950923 View in Reaxys

33/181 CAS Registry Number: 701205-13-2 Chemical Name: 5-bromo-3-(4-methylpiperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C14H18BrN3 Molecular Formula: C14H18BrN3 Molecular Weight: 308.221 InChI Key: HWXULFBLEGVJDK-UHFFFAOYSA-N Note:

Br NH

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Reaxys ID 22705329 View in Reaxys

34/181 CAS Registry Number: 383149-20-0 Chemical Name: (4-((1H-indol-3-yl)methyl)piperazin-1-yl)(furan-2-yl)methanone; 2-furyl[4-(1H-indol-3-ylmethyl)-1-piperazinyl]methanone Linear Structure Formula: C18H19N3O2 Molecular Formula: C18H19N3O2 Molecular Weight: 309.368 InChI Key: HZDVQZKEWSXXOR-UHFFFAOYSA-N Note:

O N

N O

N H

Reaxys ID 895145 View in Reaxys

35/181 CAS Registry Number: 20094-55-7 Chemical Name: 3-{[4-(4-fluorophenyl)piperazin-1-yl]methyl}-1H-indole; 3-[4-(4-fluoro-phenyl)-piperazin-1-ylmethyl]-indole; 3-<4-(4-Fluorphenyl)-1-piperazinylmethyl)indol; 3-<4-(4Fluorphenyl)piperazinomethyl)indol; HTS 06141 Linear Structure Formula: C19H20FN3 Molecular Formula: C19H20FN3 Molecular Weight: 309.386 Type of Substance: heterocyclic InChI Key: PCLWAFVRAWUFRN-UHFFFAOYSA-N Note:

N F

Reaxys ID 22848092 View in Reaxys

36/181 CAS Registry Number: 414886-17-2 Chemical Name: 3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C19H20FN3 Molecular Formula: C19H20FN3 Molecular Weight: 309.386 InChI Key: CKNQLJYCQLEECC-UHFFFAOYSA-N Note:

N F

Reaxys ID 30912989 View in Reaxys

37/181 Chemical Name: N-tert-butyloxycarbonyl-N-piperazinyl-3-indolylmethylamine Linear Structure Formula: C18H25N3O2 Molecular Formula: C18H25N3O2 Molecular Weight: 315.415 InChI Key: AUYCPBVTVLXBOP-UHFFFAOYSA-N Note:

O N

Reaxys ID 8788757 View in Reaxys

38/181

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Chemical Name: 3-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-carbonitrile; 3-[(4-phenyl-1-piperazinyl)methyl]-1H-indole-5-carbonitrile Linear Structure Formula: C20H20N4 Molecular Formula: C20H20N4 Molecular Weight: 316.406 Type of Substance: heterocyclic InChI Key: VHPASGHENHNLAW-UHFFFAOYSA-N Note:

Reaxys ID 22848094 View in Reaxys

39/181 CAS Registry Number: 1403574-75-3 Chemical Name: 3-{[4-(2-cyanophenyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C20H20N4 Molecular Formula: C20H20N4 Molecular Weight: 316.406 InChI Key: NJGIWDIZAGDKTQ-UHFFFAOYSA-N Note:

N NH

Reaxys ID 22705330 View in Reaxys

40/181 Chemical Name: ethyl 4-((5-methoxy-1H-indol-3-yl)methyl)piperazine-1-carboxylate; ethyl 4-[(5-methoxy-1H-indol-3-yl)methyl]-1-piperazinecarboxylate Linear Structure Formula: C17H23N3O3 Molecular Formula: C17H23N3O3 Molecular Weight: 317.388 InChI Key: HBYFKBGXGNUEIV-UHFFFAOYSA-N Note:

N O

N H

Reaxys ID 22848093 View in Reaxys

41/181 CAS Registry Number: 353772-99-3 Chemical Name: 3-[(4-benzoylpiperazin-1-yl)methyl]-1H-indole Linear Structure Formula: C20H21N3O Molecular Formula: C20H21N3O Molecular Weight: 319.406 InChI Key: IUSKODVEAJAQAA-UHFFFAOYSA-N Note:

O N

Reaxys ID 9720921 View in Reaxys

42/181 Chemical Name: 3-{[4-(2,3-dimethylphenyl)piperazin-1yl]methyl}-1H-indole; 3-[4-(2,3-dimethylphenyl)-piperazin-1-ylmethyl]-1H-indole Linear Structure Formula: C21H25N3 Molecular Formula: C21H25N3 Molecular Weight: 319.45 Type of Substance: heterocyclic InChI Key: WPTJQRPJBCUVFJ-UHFFFAOYSA-N Note:

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Reaxys ID 1594683 View in Reaxys

43/181 CAS Registry Number: 3414-78-6 Chemical Name: 3-(4-benzyl-piperazin-1-ylmethyl)-indol-5-ylamine Linear Structure Formula: C20H24N4 Molecular Formula: C20H24N4 Molecular Weight: 320.437 Type of Substance: heterocyclic InChI Key: FOXCFIPZINDAQU-UHFFFAOYSA-N Note:

NH H 2N N

Reaxys ID 28456677 View in Reaxys

44/181 Chemical Name: 2-(4-((5-chloro-1H-indol-3-yl)methyl)piperazin-1-yl)-N,N-dimethylethan-1-amine Linear Structure Formula: C17H25ClN4 Molecular Formula: C17H25ClN4 Molecular Weight: 320.865 InChI Key: MIXDYGNDLHIDQK-UHFFFAOYSA-N Note:

HN Cl N

N N

Reaxys ID 9717898 View in Reaxys

45/181 Chemical Name: 3-[4-(o-methoxyphenyl)-piperazin-1-ylmethyl]-1H-indole; 3-(4-(1-methoxyphen-2-yl)piperazin-1-ylmethyl)-1H-indole; HTS 04868 Linear Structure Formula: C20H23N3O Molecular Formula: C20H23N3O Molecular Weight: 321.422 Type of Substance: heterocyclic InChI Key: OJUQWLAXOIFADL-UHFFFAOYSA-N Note:

NH O N

Reaxys ID 22705328 View in Reaxys

46/181 CAS Registry Number: 864389-09-3 Chemical Name: 3-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)-1H-indole; 3-{[4-(4-methoxyphenyl)-1-piperazinyl]methyl}-1H-indole; 3-{[4-(4-methoxyphenyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C20H23N3O Molecular Formula: C20H23N3O Molecular Weight: 321.422 InChI Key: CRJJXHKBVLJRSW-UHFFFAOYSA-N Note:

N H

Reaxys ID 22848091 View in Reaxys

47/181

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CAS Registry Number: 1403574-73-1 Chemical Name: 3-{[4-(3-methoxyphenyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C20H23N3O Molecular Formula: C20H23N3O Molecular Weight: 321.422 InChI Key: OHTKFJKZUCVOHW-UHFFFAOYSA-N Note:

Reaxys ID 22705324 View in Reaxys

48/181 Chemical Name: 5-bromo-3-((4-ethylpiperazin-1-yl)methyl)-1Hindole; 5-bromo-3-[(4-ethyl-1-piperazinyl)methyl]-1H-indole Linear Structure Formula: C15H20BrN3 Molecular Formula: C15H20BrN3 Molecular Weight: 322.248 InChI Key: BCECHAQMJIAGTH-UHFFFAOYSA-N Note:

N H

Reaxys ID 11951037 View in Reaxys

49/181 CAS Registry Number: 701205-19-8 Chemical Name: 5-methoxy-3-(4-(pyridin-2-yl)piperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C19H22N4O Molecular Formula: C19H22N4O Molecular Weight: 322.41 InChI Key: PDOAZUDGOPEDOO-UHFFFAOYSA-N Note:

O NH

Reaxys ID 7543323 View in Reaxys

50/181 Chemical Name: 3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-1H-indole; 3-[4-(4-chlorophenyl)piperazin-1-yl]methylindole Linear Structure Formula: C19H20ClN3 Molecular Formula: C19H20ClN3 Molecular Weight: 325.841 Type of Substance: heterocyclic InChI Key: NRWWWLAGZMNIDV-UHFFFAOYSA-N Note:

N Cl

Reaxys ID 9718412 View in Reaxys

51/181 Chemical Name: 3-{[4-(3-chlorophenyl)piperazin-1-yl]methyl}-1H-indole; 3-[4-(m-chlorophenyl)-piperazin-1-ylmethyl]-1Hindole Linear Structure Formula: C19H20ClN3 Molecular Formula: C19H20ClN3 Molecular Weight: 325.841 Type of Substance: heterocyclic InChI Key: WQILKYINSSRSAR-UHFFFAOYSA-N Note:

Cl N

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Reaxys ID 9718517 View in Reaxys

52/181 Chemical Name: 3-{[4-(2-chlorophenyl)piperazin-1-yl]methyl}-1H-indole; 3-[4-(o-chlorophenyl)-piperazin-1-ylmethyl]-1H-indole Linear Structure Formula: C19H20ClN3 Molecular Formula: C19H20ClN3 Molecular Weight: 325.841 Type of Substance: heterocyclic InChI Key: CMZLSJOICXCPRS-UHFFFAOYSA-N Note:

NH Cl N

Reaxys ID 841199 View in Reaxys

53/181 CAS Registry Number: 34933-60-3 Chemical Name: 1-[(4-indol-3-ylmethyl-piperazin-1-yl)-acetyl]pyrrolidine; 1-(Indol-3-ylmethyl)-4-<(1-pyrrolidinyl-carbonyl)methyl>-piperazin Linear Structure Formula: C19H26N4O Molecular Formula: C19H26N4O Molecular Weight: 326.442 Type of Substance: heterocyclic InChI Key: NZMLXAWUARKVPT-UHFFFAOYSA-N Note:

N N

Reaxys ID 30912981 View in Reaxys

F F

54/181

Linear Structure Formula: C16H20F3N3O Molecular Formula: C16H20F3N3O Molecular Weight: 327.35 InChI Key: ODDYQUQEULJVME-UHFFFAOYSA-N Note:

O NH

Reaxys ID 9719223 View in Reaxys

55/181 Chemical Name: 3-(4-cinnamylpiperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C22H25N3 Molecular Formula: C22H25N3 Molecular Weight: 331.461 Type of Substance: heterocyclic InChI Key: IGNXYLSQDZTEII-UHFFFAOYSA-N Note:

Reaxys ID 568236 View in Reaxys

56/181 CAS Registry Number: 17740-70-4 Chemical Name: 1-[3-(4-phenyl-piperazin-1-ylmethyl)-indol-5yl]-ethanone Linear Structure Formula: C21H23N3O Molecular Formula: C21H23N3O Molecular Weight: 333.433 Type of Substance: heterocyclic

NH O N

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InChI Key: ZIQZINPFRFQMHE-UHFFFAOYSA-N Note:

Reaxys ID 22705333 View in Reaxys

57/181 Chemical Name: 3-((4-(furan-2-carbonyl)piperazin-1-yl)methyl)-1H-indole-5-carbonitrile; 3-{[4-(2-furoyl)-1-piperazinyl]methyl}-1H-indole-5-carbonitrile Linear Structure Formula: C19H18N4O2 Molecular Formula: C19H18N4O2 Molecular Weight: 334.378 InChI Key: UTOOYLPWUKZMGS-UHFFFAOYSA-N Note:

N N

O N H

Reaxys ID 8793130 View in Reaxys

58/181 Linear Structure Formula: C20H19N4F Molecular Formula: C20H19FN4 Molecular Weight: 334.396 Type of Substance: heterocyclic InChI Key: WSJMJBOZYZWDIK-UHFFFAOYSA-N Note:

N F

Reaxys ID 626554 View in Reaxys

59/181 CAS Registry Number: 58434-18-7 Chemical Name: N-(4-indol-3-ylmethyl-piperazin-1-yl)-benzamide Linear Structure Formula: C20H22N4O Molecular Formula: C20H22N4O Molecular Weight: 334.421 Type of Substance: heterocyclic InChI Key: HBJTWTRJRLCVMM-UHFFFAOYSA-N Note:

NH O

Reaxys ID 11725005 View in Reaxys

60/181 Chemical Name: 3-[4-(3-dimethylaminophenyl)piperazin-1yl]methylindole Linear Structure Formula: C21H26N4 Molecular Formula: C21H26N4 Molecular Weight: 334.464 InChI Key: SCMROHOCVMNFAC-UHFFFAOYSA-N Note:

N N NH N

Reaxys ID 24363549 View in Reaxys

61/181

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Linear Structure Formula: C20H21N3O2 Molecular Formula: C20H21N3O2 Molecular Weight: 335.406 InChI Key: ZGHMWJXLYLNOOG-UHFFFAOYSA-N Note:

O NH

Reaxys ID 19916687 View in Reaxys

62/181 CAS Registry Number: 414882-56-7 Chemical Name: 3-{[4-(2-ethoxyphenyl)-piperazin-1-yl]methyl}-1H-indole; 3-((4-(2-ethoxyphenyl)piperazin-1-yl)methyl)-1Hindole Linear Structure Formula: C21H25N3O Molecular Formula: C21H25N3O Molecular Weight: 335.449 InChI Key: PFALMGBZVKYODL-UHFFFAOYSA-N Note:

N N NH O

Reaxys ID 22848095 View in Reaxys

63/181 CAS Registry Number: 414882-99-8 Chemical Name: 3-{[4-(4-nitrophenyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C19H20N4O2 Molecular Formula: C19H20N4O2 Molecular Weight: 336.393 InChI Key: QEOATOUNLDHSQK-UHFFFAOYSA-N Note:

O N O

Reaxys ID 19135936 View in Reaxys

CAS Registry Number: 1008772-06-2 Chemical Name: 4-(1H-indole-3-ylmethyl)-N-pyrazin-2-ylpiperazine-1-carboxamide Linear Structure Formula: C18H20N6O Molecular Formula: C18H20N6O Molecular Weight: 336.396 InChI Key: WVNIKZYMGSQHQC-UHFFFAOYSA-N Note:

O N

64/181

N NH

Reaxys ID 28456679 View in Reaxys

65/181 Chemical Name: 5-fluoro-3-((4-(2-methoxyphenyl)piperazin-1yl)methyl)-1H-indole Linear Structure Formula: C20H22FN3O Molecular Formula: C20H22FN3O Molecular Weight: 339.413 InChI Key: FNHBWTJWVSZPGZ-UHFFFAOYSA-N Note:

HN O

F N

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2017-11-11 00:19:22

Reaxys ID 22604931 View in Reaxys

66/181 CAS Registry Number: 1345510-79-3 Chemical Name: 3-{[4-(2,5-difluorobenzyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C20H21F2N3 Molecular Formula: C20H21F2N3 Molecular Weight: 341.404 InChI Key: QXMZXABRBSZENN-UHFFFAOYSA-N Note:

F F N

Reaxys ID 5302588 View in Reaxys

67/181 CAS Registry Number: 75410-86-5 Linear Structure Formula: C22H22N4 Molecular Formula: C22H22N4 Molecular Weight: 342.443 Type of Substance: heterocyclic InChI Key: JDBVHYBVEROAAP-UHFFFAOYSA-N Note:

N N

Reaxys ID 337578 View in Reaxys

68/181 CAS Registry Number: 35713-31-6 Chemical Name: N,N'-bis(indol-3-ylmethyl)piperazine; 3,3'-piperazine-1,4-diyldimethyl-bis-indole; 1,4-bis-indol-3-ylmethyl-piperazine; 1,4-Bis-indol-3-ylmethyl-piperazin; N,N-Diskatylpiperazin Linear Structure Formula: C22H24N4 Molecular Formula: C22H24N4 Molecular Weight: 344.459 Type of Substance: heterocyclic InChI Key: WSJVQTJWVHONKW-UHFFFAOYSA-N Note:

Reaxys ID 29258003 View in Reaxys

69/181 Chemical Name: 3-[(t-butyloxycarbonylpiperazin-4-yl)methyl]-5-methoxy-1H-indole Linear Structure Formula: C19H27N3O3 Molecular Formula: C19H27N3O3 Molecular Weight: 345.442 InChI Key: KLWSFLZYJPOGSH-UHFFFAOYSA-N Note:

O N

N O

N H

Reaxys ID 22705334 View in Reaxys

70/181 Chemical Name: 3-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)-1H-indole-5-carbonitrile; 3-{[4-(4-methoxyphenyl)-1-piperazinyl]methyl}-1H-indole-5-carbonitrile Linear Structure Formula: C21H22N4O Molecular Formula: C21H22N4O Molecular Weight: 346.432

N N

N H

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2017-11-11 00:19:22

InChI Key: GOKLXLVAHUBTTB-UHFFFAOYSA-N Note:

Reaxys ID 9077921 View in Reaxys

71/181 Linear Structure Formula: C21H23N3O2 Molecular Formula: C21H23N3O2 Molecular Weight: 349.433 Type of Substance: heterocyclic InChI Key: FFBXVXKKCLEHIZ-UHFFFAOYSA-N Note:

NH O O

Reaxys ID 10289365 View in Reaxys

72/181 Chemical Name: 3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl-methyl]-1H-indole Linear Structure Formula: C21H23N3O2 Molecular Formula: C21H23N3O2 Molecular Weight: 349.433 Type of Substance: heterocyclic InChI Key: UVQHGCKWFYZHSI-UHFFFAOYSA-N Note:

NH N

N O

Reaxys ID 11672248 View in Reaxys

73/181 Chemical Name: 3-(4-(benzyloxycarbonyl)piperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C21H23N3O2 Molecular Formula: C21H23N3O2 Molecular Weight: 349.433 InChI Key: FSVZKNGFNVSDKP-UHFFFAOYSA-N Note:

O N

Reaxys ID 21558056 View in Reaxys

74/181 CAS Registry Number: 355396-63-3 Chemical Name: HTS 06142 Linear Structure Formula: C21H23N3O2 Molecular Formula: C21H23N3O2 Molecular Weight: 349.433 InChI Key: COEIFRBEMCGQEN-UHFFFAOYSA-N Note:

N N NH

Reaxys ID 1603558 View in Reaxys

75/181

17/41

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CAS Registry Number: 3414-72-0 Chemical Name: 3-(4-benzyl-piperazin-1-ylmethyl)-5-nitro-indole Linear Structure Formula: C20H22N4O2 Molecular Formula: C20H22N4O2 Molecular Weight: 350.42 Type of Substance: heterocyclic InChI Key: PKVAMSCYQLIVLR-UHFFFAOYSA-N Note:

NH O

N O

Reaxys ID 8792889 View in Reaxys

76/181 Linear Structure Formula: C20H19N4Cl Molecular Formula: C20H19ClN4 Molecular Weight: 350.851 Type of Substance: heterocyclic InChI Key: SNFLVHDMWFYRRB-UHFFFAOYSA-N Note:

NH Cl N

Reaxys ID 8793434 View in Reaxys

77/181 Linear Structure Formula: C20H19N4Cl Molecular Formula: C20H19ClN4 Molecular Weight: 350.851 Type of Substance: heterocyclic InChI Key: HYLGECOKUPPDRN-UHFFFAOYSA-N Note:

N Cl

Reaxys ID 11951133 View in Reaxys

78/181 CAS Registry Number: 701205-17-6 Chemical Name: 5-methoxy-3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1H-indole; 5-methoxy-3-{[4-(2-methoxyphenyl)-1-piperazinyl]methyl}-1H-indole; 5-methoxy-3-(4-(1-methoxyphen-2-yl)piperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C21H25N3O2 Molecular Formula: C21H25N3O2 Molecular Weight: 351.448 InChI Key: MBYXPBOWSBKBJN-UHFFFAOYSA-N Note:

N O

O NH

Reaxys ID 628593 View in Reaxys

79/181 CAS Registry Number: 58434-20-1 Chemical Name: 4-fluoro-N-(4-indol-3-ylmethyl-piperazin-1-yl)benzamide Linear Structure Formula: C20H21FN4O Molecular Formula: C20H21FN4O Molecular Weight: 352.411 Type of Substance: heterocyclic InChI Key: BHBRWSQWUNNUOO-UHFFFAOYSA-N Note:

NH O

18/41

2017-11-11 00:19:22

Reaxys ID 11725009 View in Reaxys

80/181 Chemical Name: 3-[4-(4-chloro-3-methoxyphenyl)piperazin-1yl]methylindole Linear Structure Formula: C20H22ClN3O Molecular Formula: C20H22ClN3O Molecular Weight: 355.867 InChI Key: LSSGXUSYGHZTJW-UHFFFAOYSA-N Note:

N N NH

Cl O

Reaxys ID 9726366 View in Reaxys

81/181 Chemical Name: 3-[4-(m-trifluoromethylphenyl)-piperazin-1-ylmethyl]-1H-indole Linear Structure Formula: C20H20F3N3 Molecular Formula: C20H20F3N3 Molecular Weight: 359.394 Type of Substance: heterocyclic InChI Key: CVIYNLVHJXVVIA-UHFFFAOYSA-N Note:

NH F

F F

Reaxys ID 11725008 View in Reaxys

82/181 Chemical Name: 5-chloro-3-[4-(4-chlorophenyl)piperazin-1yl]methylindole Linear Structure Formula: C19H19Cl2N3 Molecular Formula: C19H19Cl2N3 Molecular Weight: 360.286 InChI Key: XUCYZJZBUAWKGX-UHFFFAOYSA-N Note:

Cl N N NH

Reaxys ID 23870534 View in Reaxys

83/181 CAS Registry Number: 1451194-28-7 Chemical Name: 3-{[4-(2,3-dichlorophenyl)-piperazin-1yl]methyl}-1H-indole Linear Structure Formula: C19H19Cl2N3 Molecular Formula: C19H19Cl2N3 Molecular Weight: 360.286 InChI Key: SVSNQBMLUDOWHS-UHFFFAOYSA-N Note:

Reaxys ID 25966194 View in Reaxys

84/181 CAS Registry Number: 1348317-84-9 Linear Structure Formula: C19H20ClN3*ClH Molecular Formula: C19H20ClN3*ClH Molecular Weight: 362.302 InChI Key: NIOIXSOSEQDRML-UHFFFAOYSA-N Note:

Cl N HCl

19/41

2017-11-11 00:19:22

Reaxys ID 28456678 View in Reaxys HO

85/181 Chemical Name: 2-(4-((5-chloro-1H-indol-3-yl)methyl)piperazin-1-yl)-N,N-dimethylethan-1-amine formic acid salt Linear Structure Formula: C17H25ClN4*CH2O2 Molecular Formula: CH2O2*C17H25ClN4 Molecular Weight: 366.891 InChI Key: POLNIUXNISKWMR-UHFFFAOYSA-N Note:

O HN Cl N

N N

Reaxys ID 22705327 View in Reaxys

86/181 Chemical Name: 5-bromo-3-((4-phenylpiperazin-1-yl)methyl)-1H-indole; 5-bromo-3-[(4-phenyl-1-piperazinyl)methyl]-1H-indole Linear Structure Formula: C19H20BrN3 Molecular Formula: C19H20BrN3 Molecular Weight: 370.292 InChI Key: WUFFRSHCMYNTJG-UHFFFAOYSA-N Note:

Br N

N H

Reaxys ID 11951030 View in Reaxys

87/181 CAS Registry Number: 701205-18-7 Chemical Name: 5-bromo-3-(4-(pyridin-2-yl)piperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C18H19BrN4 Molecular Formula: C18H19BrN4 Molecular Weight: 371.28 InChI Key: PINBXRZSNRLKID-UHFFFAOYSA-N Note:

Br NH

Reaxys ID 25587862 View in Reaxys O HO

88/181 Linear Structure Formula: C20H28N4O3 Molecular Formula: C20H28N4O3 Molecular Weight: 372.467 InChI Key: YKNWOJOWNPOJRJ-UHFFFAOYSA-N Note:

N H

N N

Reaxys ID 22604930 View in Reaxys

89/181 CAS Registry Number: 1345510-80-6 Chemical Name: 3-{[4-(3,4-dichlorobenzyl)piperazin-1-yl]methyl}-1H-indole Linear Structure Formula: C20H21Cl2N3 Molecular Formula: C20H21Cl2N3 Molecular Weight: 374.313 InChI Key: GBYXTIZDOIKXPZ-UHFFFAOYSA-N Note:

Cl Cl

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2017-11-11 00:19:22

Reaxys ID 29599928 View in Reaxys

90/181 Chemical Name: 4-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)-7chloroquinoline; 4-(4-((1H-Indol-3-yl)methyl)piperazin-1-yl)-7chloroquinoline Linear Structure Formula: C22H21ClN4 Molecular Formula: C22H21ClN4 Molecular Weight: 376.889 InChI Key: YSZQCJMJIIWGKU-UHFFFAOYSA-N Note:

N HN

N N

Reaxys ID 28456685 View in Reaxys

91/181

Chemical Name: 3-((4-(2,3-dichlorophenyl)piperazin-1-yl)methyl)-5-fluoro-1H-indole Linear Structure Formula: C19H18Cl2FN3 Molecular Formula: C19H18Cl2FN3 Molecular Weight: 378.276 InChI Key: KRVNZLXHWSPXEE-UHFFFAOYSA-N Note:

Cl N N F HN

Reaxys ID 18483400 View in Reaxys

92/181 CAS Registry Number: 1056000-42-0 Chemical Name: [3-(4-cyclobutyl-piperazin-1-ylmethyl)-1H-indol-5-yl]-piperidin-1-yl-methanone Linear Structure Formula: C23H32N4O Molecular Formula: C23H32N4O Molecular Weight: 380.533 InChI Key: XNTLEJQKHHOXOJ-UHFFFAOYSA-N Note:

N O

NH N

Reaxys ID 19332291 View in Reaxys N

93/181 CAS Registry Number: 1166813-01-9 Linear Structure Formula: C19H19F2N7 Molecular Formula: C19H19F2N7 Molecular Weight: 383.404 InChI Key: YKSTVEVHSRIWRH-UHFFFAOYSA-N Note:

N N

F F

Reaxys ID 8798976 View in Reaxys

94/181

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Linear Structure Formula: C20H18N4Cl2 Molecular Formula: C20H18Cl2N4 Molecular Weight: 385.296 Type of Substance: heterocyclic InChI Key: LLMBUJCYVGLEBH-UHFFFAOYSA-N Note:

N Cl

Reaxys ID 28456680 View in Reaxys

95/181 Chemical Name: 5-fluoro-3-((4-(2-methoxyphenyl)piperazin-1yl)methyl)-1H-indole formic acid salt Linear Structure Formula: C20H22FN3O*CH2O2 Molecular Formula: CH2O2*C20H22FN3O Molecular Weight: 385.438 InChI Key: CVQDWSOBERUNJM-UHFFFAOYSA-N Note:

HN O

F N

Reaxys ID 11725014 View in Reaxys

96/181 Chemical Name: 3-[4-(4-chloro-2,5-dimethoxyphenyl)piperazin-1-yl]methylindole Linear Structure Formula: C21H24ClN3O2 Molecular Formula: C21H24ClN3O2 Molecular Weight: 385.893 InChI Key: DWFKVFVRIJSCBL-UHFFFAOYSA-N Note:

N N NH

Cl O

Reaxys ID 25587847 View in Reaxys

97/181 Linear Structure Formula: C21H30N4O3 Molecular Formula: C21H30N4O3 Molecular Weight: 386.494 InChI Key: UYQOFILLYJJDJD-UHFFFAOYSA-N Note:

H N

N O

Reaxys ID 31231727 View in Reaxys

98/181

Chemical Name: N-[N-(3-indolylmethyl)-aminoethyl]-N-piperazinyl-3-indolylmethylamine Linear Structure Formula: C24H29N5 Molecular Formula: C24H29N5 Molecular Weight: 387.528 InChI Key: NPDSIOQSXZZAFX-UHFFFAOYSA-N Note:

N NH

Reaxys ID 22705331 View in Reaxys

99/181

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Linear Structure Formula: C18H18BrN3O2 Molecular Formula: C18H18BrN3O2 Molecular Weight: 388.264 InChI Key: KWSRXGSGJKPCNC-UHFFFAOYSA-N Note:

N O

N H

Reaxys ID 27144079 View in Reaxys

100/181 CAS Registry Number: 355823-76-6 Linear Structure Formula: C23H29N3O3 Molecular Formula: C23H29N3O3 Molecular Weight: 395.502 InChI Key: QXQHDEHOKNWVNF-UHFFFAOYSA-N Note:

O NH

N N

O O

Reaxys ID 31173349 View in Reaxys

101/181 Linear Structure Formula: C23H29N3O3 Molecular Formula: C23H29N3O3 Molecular Weight: 395.502 InChI Key: SKTMFTDDYHSSIN-UHFFFAOYSA-N Note:

N N

O O

Reaxys ID 12317637 View in Reaxys

O O

Linear Structure Formula: C20H24N6O3 Molecular Formula: C20H24N6O3 Molecular Weight: 396.449 InChI Key: FEWWLHCFEBYWGW-UHFFFAOYSA-N Note:

102/181

Reaxys ID 14173459 View in Reaxys

103/181

H N HN

CAS Registry Number: 528860-17-5 Chemical Name: [41] N-[3-(4-methylpiperazin-1-yl)methyl-1Hindol-5-yl]-α-toluenesulphonamide; N-[3-(4-methylpiperazin-1yl)methyl-1H-indol-5-yl]-α-toluenesulphonamide; N-[3-(4-methylpiperazin-1-yl)methyl-1H-indol-5-yl]-α-toluenesulphonamide Linear Structure Formula: C21H26N4O2S Molecular Formula: C21H26N4O2S Molecular Weight: 398.529 InChI Key: IOJVMOAYKYBHST-UHFFFAOYSA-N Note:

S O

23/41

2017-11-11 00:19:22

Reaxys ID 11951128 View in Reaxys

104/181 CAS Registry Number: 701205-16-5 Chemical Name: 5-bromo-3-(4-(1-methoxyphen-2-yl)piperazin-1-ylmethyl)-1H-indole Linear Structure Formula: C20H22BrN3O Molecular Formula: C20H22BrN3O Molecular Weight: 400.318 InChI Key: FSGUUQJMURQGAW-UHFFFAOYSA-N Note:

N Br

O NH

Reaxys ID 22705332 View in Reaxys

105/181

Chemical Name: 5-bromo-3-{[4-(4-methoxyphenyl)-1-piperazinyl]methyl}-1H-indole Linear Structure Formula: C20H22BrN3O Molecular Formula: C20H22BrN3O Molecular Weight: 400.318 InChI Key: BYIWJSNUXJJKNX-UHFFFAOYSA-N Note:

N H

Reaxys ID 24428086 View in Reaxys

106/181

Linear Structure Formula: C20H19F3N6 Molecular Formula: C20H19F3N6 Molecular Weight: 400.406 Note:

N N

F F

Reaxys ID 19332396 View in Reaxys

107/181

CAS Registry Number: 1166813-33-7 Linear Structure Formula: C19H18F3N7 Molecular Formula: C19H18F3N7 Molecular Weight: 401.394 InChI Key: GPTAPLOYDQZRFX-UHFFFAOYSA-N Note:

N N

N F F

Reaxys ID 19332422 View in Reaxys

108/181 CAS Registry Number: 1166811-03-5 Chemical Name: 6-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]-3(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine Linear Structure Formula: C19H18F3N7 Molecular Formula: C19H18F3N7 Molecular Weight: 401.394 InChI Key: YHGQQKFBDVHQFM-UHFFFAOYSA-N Note:

N HN

N N

F F

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Reaxys ID 20623266 View in Reaxys

109/181 CAS Registry Number: 1240299-43-7 Chemical Name: 6-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]-3(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazine Linear Structure Formula: C19H20F3N7 Molecular Formula: C19H20F3N7 Molecular Weight: 403.41 InChI Key: AUBNKPBCVWTIIG-UHFFFAOYSA-N Note:

N N

Reaxys ID 11725015 View in Reaxys

110/181 O

Chemical Name: 5-methanesulfonyl-3-[4-(4-chlorophenyl)piperazin-1-yl]methylindole Linear Structure Formula: C20H22ClN3O2S Molecular Formula: C20H22ClN3O2S Molecular Weight: 403.933 InChI Key: RLQSXVIABFBZGJ-UHFFFAOYSA-N Note:

O S

N N NH

Reaxys ID 19332444 View in Reaxys

111/181

CAS Registry Number: 1166813-28-0 Linear Structure Formula: C20H18F2N8 Molecular Formula: C20H18F2N8 Molecular Weight: 408.413 InChI Key: VHGCZEIQFHAMMD-UHFFFAOYSA-N Note:

Reaxys ID 14173860 View in Reaxys

112/181

O N

CAS Registry Number: 528860-05-1 Chemical Name: N-[3-(4-methylpiperazin-1-yl)methyl-1H-indol-5-yl]-trans-β-styrenesulphonamide; N-[3-(4-methylpiperazin-1-yl)methyl-1H-indol-5-yl]-trans-β-styrenesulphonamide; N[3-(4-methylpiperazin-1-yl)methyl-1H-indol-5-yl]-trans-3-styrenesulphonamide Linear Structure Formula: C22H26N4O2S Molecular Formula: C22H26N4O2S Molecular Weight: 410.54 InChI Key: JYFZTHMGIJASIF-NTEUORMPSA-N Note:

S NH

Reaxys ID 25292007 View in Reaxys HN

113/181 Linear Structure Formula: C22H26N4O2S Molecular Formula: C22H26N4O2S Molecular Weight: 410.54 InChI Key: XKJTZDFTSAZUEV-UHFFFAOYSA-N Note:

O N H

S O

25/41

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Reaxys ID 15337111 View in Reaxys

114/181 CAS Registry Number: 350850-00-9 Chemical Name: 1-[(4-Cyano-5-methyl-4-phenyl)hexyl]-4-[(3indolyl)methyl]piperazine Linear Structure Formula: C27H34N4 Molecular Formula: C27H34N4 Molecular Weight: 414.594 InChI Key: AYCOHRNAXUGXCP-UHFFFAOYSA-N Note:

N HN

Reaxys ID 25120862 View in Reaxys

115/181 Linear Structure Formula: C24H22FN5O Molecular Formula: C24H22FN5O Molecular Weight: 415.47 InChI Key: BAEVARPPYYAVPQ-UHFFFAOYSA-N Note:

HN F O

Reaxys ID 29891289 View in Reaxys

116/181

Linear Structure Formula: C25H25FN4O Molecular Formula: C25H25FN4O Molecular Weight: 416.498 InChI Key: DPIIFXNAGCUCFF-UHFFFAOYSA-N Note:

N HN

F N H

Reaxys ID 25209760 View in Reaxys

117/181

O N

Linear Structure Formula: C25H31N5O Molecular Formula: C25H31N5O Molecular Weight: 417.554 InChI Key: JHVLNPHVAJOJTR-UHFFFAOYSA-N Note:

Reaxys ID 19332392 View in Reaxys N

118/181 CAS Registry Number: 1166813-29-1 Linear Structure Formula: C19H18ClF2N7 Molecular Formula: C19H18ClF2N7 Molecular Weight: 417.849 InChI Key: QXIKGVSTVMMSLI-UHFFFAOYSA-N Note:

N N

N Cl F

26/41

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Reaxys ID 24428089 View in Reaxys

119/181

Linear Structure Formula: C20H18F4N6 Molecular Formula: C20H18F4N6 Molecular Weight: 418.397 Note:

F F

Reaxys ID 11725016 View in Reaxys

120/181 O

Chemical Name: N-methyl-3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]-5-indolesulfonamide Linear Structure Formula: C20H23ClN4O2S Molecular Formula: C20H23ClN4O2S Molecular Weight: 418.947 InChI Key: QCPPIIFNZUDTSX-UHFFFAOYSA-N Note:

O S

N H

N N NH

Reaxys ID 19332482 View in Reaxys

121/181

CAS Registry Number: 1166813-24-6 Linear Structure Formula: C19H17F4N7 Molecular Formula: C19H17F4N7 Molecular Weight: 419.384 InChI Key: KLOXENUKOZCWFV-UHFFFAOYSA-N Note:

N F

F F

Reaxys ID 11752122 View in Reaxys

122/181 Chemical Name: 6-(5-(4-(1H-indol-3-ylmethyl)-piperazin-1-yl)pyridin-3-yl)-isoquinoline Linear Structure Formula: C27H25N5 Molecular Formula: C27H25N5 Molecular Weight: 419.529 InChI Key: SCWIRSFEUFHHKA-UHFFFAOYSA-N Note:

N NH

N N

Reaxys ID 20623282 View in Reaxys

123/181 CAS Registry Number: 1240299-44-8 Chemical Name: 6-{4-[(5-fluoro-1H-indol-3-yl)methyl]piperazin-1-yl}-3-(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazine Linear Structure Formula: C19H19F4N7 Molecular Formula: C19H19F4N7 Molecular Weight: 421.4 InChI Key: WEJKWKWMCGZGBL-UHFFFAOYSA-N Note:

F N N HN

N F

F F

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Reaxys ID 632470 View in Reaxys

124/181 CAS Registry Number: 58434-19-8 Chemical Name: N-(4-indol-3-ylmethyl-piperazin-1-yl)-3,4,5-trimethoxy-benzamide Linear Structure Formula: C23H28N4O4 Molecular Formula: C23H28N4O4 Molecular Weight: 424.5 Type of Substance: heterocyclic InChI Key: MYYUMVOCRJWWIZ-UHFFFAOYSA-N Note:

NH O

O O

Reaxys ID 25673014 View in Reaxys

125/181 CAS Registry Number: 1166818-94-5 Linear Structure Formula: C21H18F3N7 Molecular Formula: C21H18F3N7 Molecular Weight: 425.416 InChI Key: GIYGJFXAZCJZHE-UHFFFAOYSA-N Note:

N N

F F

Reaxys ID 19332518 View in Reaxys

126/181

CAS Registry Number: 1166813-18-8 Linear Structure Formula: C20H17F3N8 Molecular Formula: C20H17F3N8 Molecular Weight: 426.404 InChI Key: DQEVPJDXAAJOMS-UHFFFAOYSA-N Note:

F F

Reaxys ID 20623289 View in Reaxys

127/181 CAS Registry Number: 1240299-45-9 Chemical Name: 3-({4-[3-(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazin-1-yl}methyl)-1H-indole-5carbonitrile Linear Structure Formula: C20H19F3N8 Molecular Formula: C20H19F3N8 Molecular Weight: 428.42 InChI Key: VOTLZURATNBCQE-UHFFFAOYSA-N Note:

N N

N H

F F

Reaxys ID 31639373 View in Reaxys

128/181

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Chemical Name: 1-benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-indol-5-yl)-1H-pyrazole-4-carboxamide Linear Structure Formula: C25H28N6O Molecular Formula: C25H28N6O Molecular Weight: 428.537 InChI Key: NOJHMLGDGWPYAT-UHFFFAOYSA-N Note:

N H N

N O

Reaxys ID 19332475 View in Reaxys

129/181

CAS Registry Number: 1166813-20-2 Linear Structure Formula: C19H17ClF3N7 Molecular Formula: C19H17ClF3N7 Molecular Weight: 435.839 InChI Key: MZDUDKZZKOVNNE-UHFFFAOYSA-N Note:

N N

N Cl F F

Reaxys ID 13059875 View in Reaxys N

130/181 Linear Structure Formula: C25H26N8 Molecular Formula: C25H26N8 Molecular Weight: 438.535 InChI Key: OSDSSWSLYXXJIH-UHFFFAOYSA-N Note:

N N HN

N NH 2

Reaxys ID 9299383 View in Reaxys

131/181 Chemical Name: 8-chloro-11-{4-[(1H-indol-3-yl)methyl]piperazino}-5H-dibenzo[b,e][1,4]diazepine Linear Structure Formula: C26H24ClN5 Molecular Formula: C26H24ClN5 Molecular Weight: 441.963 Type of Substance: heterocyclic InChI Key: XRRJUQKQCOYQDM-UHFFFAOYSA-N Note:

H N Cl N N N HN

Reaxys ID 22690399 View in Reaxys

132/181

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CAS Registry Number: 1381992-14-8 Chemical Name: 6-({2-[4-(1H-indol-3-ylmethyl)piperazin-1yl]ethyl}propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol Linear Structure Formula: C28H38N4O Molecular Formula: C28H38N4O Molecular Weight: 446.636 InChI Key: UHRDDHPBSKWWGI-UHFFFAOYSA-N Note:

OH N N

Reaxys ID 9302328 View in Reaxys

133/181 Chemical Name: 8-chloro-11-{4-[(5-hydroxy-1H-indol-3yl)methyl]piperazino}-5H-dibenzo[b,e][1,4]diazepine Linear Structure Formula: C26H24ClN5O Molecular Formula: C26H24ClN5O Molecular Weight: 457.962 Type of Substance: heterocyclic InChI Key: IMTHIGQRYFSTIP-UHFFFAOYSA-N Note:

H N Cl N N N HN

Reaxys ID 19332393 View in Reaxys

134/181

CAS Registry Number: 1166813-31-5 Linear Structure Formula: C19H18BrF2N7 Molecular Formula: C19H18BrF2N7 Molecular Weight: 462.3 InChI Key: DZRBIROXFUGWJH-UHFFFAOYSA-N Note:

N N

N Br F

Reaxys ID 6165617 View in Reaxys

135/181 Chemical Name: 2-<2-<4-((5-fluoro-1H-indol-3-yl)methyl)-1-piperazinyl>ethyl>-2H-naphth<1,8-cd>isothiazole 1,1-dioxide Linear Structure Formula: C25H25FN4O2S Molecular Formula: C25H25FN4O2S Molecular Weight: 464.564 Type of Substance: heterocyclic InChI Key: VDYVPBAJQCJILV-UHFFFAOYSA-N Note:

N O O

Reaxys ID 21907482 View in Reaxys

136/181

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CAS Registry Number: 1266605-65-5 Linear Structure Formula: C25H28F2N6O Molecular Formula: C25H28F2N6O Molecular Weight: 466.534 InChI Key: QLDMLILLPALAOJ-IQGLISFBSA-N Note:

N N N

F HN F

Reaxys ID 31105801 View in Reaxys

137/181 Chemical Name: N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1yl)-5-(trifluoromethyl)phenyl)furan-2-carboxamide Linear Structure Formula: C25H23F3N4O2 Molecular Formula: C25H23F3N4O2 Molecular Weight: 468.478 InChI Key: FFLVVHKDKKCYLU-UHFFFAOYSA-N Note:

F F

F O N H

N NH

Reaxys ID 12817239 View in Reaxys

Linear Structure Formula: C27H33N7O Molecular Formula: C27H33N7O Molecular Weight: 471.605 InChI Key: XTXCESRFEUTRRC-VWLOTQADSA-N Note:

NH 2

HN N N

138/181

N N

Reaxys ID 9301970 View in Reaxys

139/181 CAS Registry Number: 507263-43-6 Chemical Name: 8-chloro-11-{4-[(5-methoxy-1H-indol-3yl)methyl]piperazino}-5H-dibenzo[b,e][1,4]diazepine Linear Structure Formula: C27H26ClN5O Molecular Formula: C27H26ClN5O Molecular Weight: 471.989 Type of Substance: heterocyclic InChI Key: ZRIRCTNRDXEQKJ-UHFFFAOYSA-N Note:

H N Cl N N N HN

Reaxys ID 12051632 View in Reaxys

140/181

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Linear Structure Formula: C29H27N5O2 Molecular Formula: C29H27N5O2 Molecular Weight: 477.566 InChI Key: BMOKEYVONUEXPM-UHFFFAOYSA-N Note:

O NH N

O N N

Reaxys ID 31105712 View in Reaxys

141/181 Chemical Name: N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1yl)-5-(trifluoromethyl)phenyl)picolinamide Linear Structure Formula: C26H24F3N5O Molecular Formula: C26H24F3N5O Molecular Weight: 479.505 InChI Key: HGUWBZCQIAPPLU-UHFFFAOYSA-N Note:

F F

F O N H

N NH

Reaxys ID 19332483 View in Reaxys N

142/181 CAS Registry Number: 1166813-22-4 Linear Structure Formula: C19H17BrF3N7 Molecular Formula: C19H17BrF3N7 Molecular Weight: 480.29 InChI Key: JSNIQHXGQRJBCK-UHFFFAOYSA-N Note:

N N

F F

Reaxys ID 22432078 View in Reaxys

143/181 CAS Registry Number: 1266605-77-9 Linear Structure Formula: C26H30F2N6O Molecular Formula: C26H30F2N6O Molecular Weight: 480.561 InChI Key: ZEAHDUPFIJMATC-NIYFSFCBSA-N Note:

N N

OH N

Reaxys ID 25844291 View in Reaxys

144/181

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CAS Registry Number: 1349521-83-0 Linear Structure Formula: C26H33FN6O2 Molecular Formula: C26H33FN6O2 Molecular Weight: 480.585 InChI Key: BZGZNRCUJNTVKR-UHFFFAOYSA-N Note:

HN F N N

NH N

O O

Reaxys ID 22432084 View in Reaxys

145/181

N N

OH N

CAS Registry Number: 1266605-73-5 Chemical Name: (2R,3R)-2-(2,4-difluorophenyl)-3-[4-(5-fluoro-1H-indol-3-ylmethyl)-piperazin-1-yl]-1-(1H-1,2,4-triazol-1yl)butan-2-ol Linear Structure Formula: C25H27F3N6O Molecular Formula: C25H27F3N6O Molecular Weight: 484.524 InChI Key: VDCDFMWDUGKVSJ-CRICUBBOSA-N Note:

Reaxys ID 14181097 View in Reaxys

146/181 CAS Registry Number: 528859-48-5 Chemical Name: [851] N-[3-(4-methylpiperazin-1-yl)methyl-1Hindol-5-yl]-5-chloro-3-methylbenzo[b]thiophene-2-sulphonamide; [19] N-[3-(4-methylpiperazin-1-yl)methyl-1H-indol-5-yl]-5chloro-3-methylbenzo[b]thiophene-2-sulphonamide; N-[3-(4methylpiperazin-1-yl)methyl-1H-indol-5-yl]-5-chloro-3-methylbenzo[b]thiophene-2-sulphonamide Linear Structure Formula: C23H25ClN4O2S2 Molecular Formula: C23H25ClN4O2S2 Molecular Weight: 489.062 InChI Key: HYKSBOYHYALPPR-UHFFFAOYSA-N Note:

N N

O O

S NH

Reaxys ID 22432088 View in Reaxys

147/181 CAS Registry Number: 1266605-82-6 Linear Structure Formula: C26H27F2N7O Molecular Formula: C26H27F2N7O Molecular Weight: 491.543 InChI Key: VNEDIPQYIHKWLB-WXTAPIANSA-N Note:

N N N

N N

OH N

Reaxys ID 22432085 View in Reaxys

148/181

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OH N

CAS Registry Number: 1266605-80-4 Linear Structure Formula: C26H30F2N6O2 Molecular Formula: C26H30F2N6O2 Molecular Weight: 496.56 InChI Key: UAFYUKBSJYTLOY-WXTAPIANSA-N Note:

Reaxys ID 11992643 View in Reaxys

149/181 CAS Registry Number: 731825-08-4 Chemical Name: 9-(4,5-dimethyl-thiazol-2-yl)-4-[4-(1H-indol-3ylmethyl)-piperazin-1-yl]-5,6,7,8-tetrahydro-1,3,4b-triaza-fluorene Linear Structure Formula: C28H31N7S Molecular Formula: C28H31N7S Molecular Weight: 497.667 InChI Key: OHSSKNYHOIZQRB-UHFFFAOYSA-N Note:

N N N

N S

Reaxys ID 25760769 View in Reaxys

150/181 CAS Registry Number: 1349661-17-1 Linear Structure Formula: C28H31N7S Molecular Formula: C28H31N7S Molecular Weight: 497.667 InChI Key: AMOXTCKQRAEICA-UHFFFAOYSA-N Note:

N N

Reaxys ID 22432075 View in Reaxys

151/181

OH N

CAS Registry Number: 1266605-75-7 Linear Structure Formula: C25H27ClF2N6O Molecular Formula: C25H27ClF2N6O Molecular Weight: 500.979 InChI Key: VMVQVNNCFZWQTK-CRICUBBOSA-N Note:

Reaxys ID 22432093 View in Reaxys

152/181 N

N N

CAS Registry Number: 1266605-81-5 Linear Structure Formula: C25H27F2N9O Molecular Formula: C25H27F2N9O Molecular Weight: 507.546 InChI Key: OOYHOUHWHUVJMQ-CRICUBBOSA-N Note:

N N

OH N

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Reaxys ID 25120863 View in Reaxys

153/181

O N

Linear Structure Formula: C25H22F6N4O Molecular Formula: C25H22F6N4O Molecular Weight: 508.466 InChI Key: CIFOCVBJYGFAPD-UHFFFAOYSA-N Note:

F F HN

F F F

Reaxys ID 26087883 View in Reaxys

F O

154/181 Linear Structure Formula: C2HF3O2*C23H27FN4O Molecular Formula: C2HF3O2*C23H27FN4O Molecular Weight: 508.516 InChI Key: XOJZRTVYJDAINI-FSRHSHDFSA-N Note:

F NH 2

F F

Reaxys ID 20725055 View in Reaxys

155/181 Linear Structure Formula: C29H28N6O3 Molecular Formula: C29H28N6O3 Molecular Weight: 508.58 InChI Key: ZCIAWRZDKXSETI-UHFFFAOYSA-N Note:

O NH

N N

Reaxys ID 22432087 View in Reaxys

156/181 CAS Registry Number: 1266605-83-7 Linear Structure Formula: C26H29F2N7O2 Molecular Formula: C26H29F2N7O2 Molecular Weight: 509.559 InChI Key: XWNWLUXBJDZSEX-WXTAPIANSA-N Note:

OH N

N N

OH N

Reaxys ID 22432091 View in Reaxys

157/181 O N

N N

OH N

CAS Registry Number: 1266605-79-1 Linear Structure Formula: C25H27F2N7O3 Molecular Formula: C25H27F2N7O3 Molecular Weight: 511.531 InChI Key: FAGHMIXGHHCEPF-CRICUBBOSA-N Note:

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Reaxys ID 31558258 View in Reaxys HN

Chemical Name: methyl (Z)-3-(((3-((4-methylpiperazin-1yl)methyl)-1H-indol-5-yl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Linear Structure Formula: C31H31N5O3 Molecular Formula: C31H31N5O3 Molecular Weight: 521.619 InChI Key: XNLAEVVAFHZWEB-ZIADKAODSA-N Note:

H N

158/181

Reaxys ID 12065107 View in Reaxys

159/181 Chemical Name: 1-(4-{5-[6-amino-5-(2,6-dichloro-benzyloxy)pyridin-3-yl]-1H-indol-3-ylmethyl}-piperazin-1-yl)-ethanone Linear Structure Formula: C27H27Cl2N5O2 Molecular Formula: C27H27Cl2N5O2 Molecular Weight: 524.45 InChI Key: OYACPHQVNCYSTD-UHFFFAOYSA-N Note:

N NH 2

HN O

Cl N O

Reaxys ID 12065459 View in Reaxys

160/181 Chemical Name: 1-(4-{5-[6-amino-5-(2-chloro-3,6-difluoro-benzyloxy)-pyridin-3-yl]-1H-indol-3-ylmethyl}-piperazin-1-yl)-ethanone Linear Structure Formula: C27H26ClF2N5O2 Molecular Formula: C27H26ClF2N5O2 Molecular Weight: 525.986 InChI Key: IFALZBXDPWLSSQ-UHFFFAOYSA-N Note:

N NH 2

HN O

F N O

Reaxys ID 12065502 View in Reaxys

161/181 Chemical Name: 1-(4-{5-[5-amino-6-(2-chloro-3,6-difluoro-benzyloxy)-pyrazin-2-yl]-1H-indol-3-ylmethyl}-piperazin-1-yl)-ethanone Linear Structure Formula: C26H25ClF2N6O2 Molecular Formula: C26H25ClF2N6O2 Molecular Weight: 526.973 InChI Key: WREGOQQTMQTCDW-UHFFFAOYSA-N Note:

F HN

O N

F N

NH 2

Reaxys ID 26194769 View in Reaxys

162/181

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Linear Structure Formula: C28H30F2N6O3 Molecular Formula: C28H30F2N6O3 Molecular Weight: 536.581 InChI Key: BYDDVYPSKQEEAJ-UQDIGLKLSA-N Note:

N N F

N E

Reaxys ID 22432082 View in Reaxys

163/181

OH N

CAS Registry Number: 1266605-76-8 Linear Structure Formula: C25H27BrF2N6O Molecular Formula: C25H27BrF2N6O Molecular Weight: 545.43 InChI Key: IQNKQOUNDLEETD-CRICUBBOSA-N Note:

Reaxys ID 28817958 View in Reaxys

164/181

Chemical Name: N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1yl)-5-(trifluoromethyl)phenyl)-5-(pyridin-4-yl)furan-2-carboxamide Linear Structure Formula: C30H26F3N5O2 Molecular Formula: C30H26F3N5O2 Molecular Weight: 545.564 InChI Key: PXTGGKHRMSAKSB-UHFFFAOYSA-N Note:

O N H

N N NH

Reaxys ID 12251232 View in Reaxys

165/181 Chemical Name: 3-{4-[[1-(2,6-dimethylphenyl)-1H-tetrazol-5yl]-(3-trifluoromethylphenyl)methyl]piperazin-1-ylmethyl}-1H-indole Linear Structure Formula: C30H30F3N7 Molecular Formula: C30H30F3N7 Molecular Weight: 545.61 InChI Key: CKAZCJFSWDKTAZ-UHFFFAOYSA-N Note:

F HN

F N

N N

Reaxys ID 25024367 View in Reaxys

166/181

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Linear Structure Formula: C30H30F3N7 Molecular Formula: C30H30F3N7 Molecular Weight: 545.61 InChI Key: CKAZCJFSWDKTAZ-NDEPHWFRSA-N Note:

HN N

N N

F F F

Reaxys ID 22981168 View in Reaxys O

CAS Registry Number: 1403360-01-9 Linear Structure Formula: C27H27F3N6O4 Molecular Formula: C27H27F3N6O4 Molecular Weight: 556.544 InChI Key: PRQPTJGEDHERPW-UHFFFAOYSA-N Note:

N O

167/181

N N

F F

Reaxys ID 380252 View in Reaxys

168/181 CAS Registry Number: 103401-68-9 Chemical Name: 1,4-bis-(5-benzyloxy-indol-3-ylmethyl)-piperazine; 1,4-Bis-(5-benzyloxy-indol-3-ylmethyl)-piperazin Linear Structure Formula: C36H36N4O2 Molecular Formula: C36H36N4O2 Molecular Weight: 556.707 Type of Substance: heterocyclic InChI Key: CGCRHVIYJGBKHL-UHFFFAOYSA-N Note:

NH O N

N O HN

Reaxys ID 27604342 View in Reaxys

169/181 Chemical Name: 4-{4-[(4-((1H-indol-3-yl)methyl)piperazin-1yl)methyl]-1H-1,2,3-triazol-1-yl}-2,8-bis(trifluoromethyl)quinoline Linear Structure Formula: C27H23F6N7 Molecular Formula: C27H23F6N7 Molecular Weight: 559.517 InChI Key: MPXYFBKYQYXTLZ-UHFFFAOYSA-N Note:

N N

F F N

F F

Reaxys ID 12637634 View in Reaxys

170/181

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Linear Structure Formula: C31H40FN7O2 Molecular Formula: C31H40FN7O2 Molecular Weight: 561.703 InChI Key: QXDUUKULQWPOKB-UHFFFAOYSA-N Note:

N F

Reaxys ID 14142573 View in Reaxys

171/181 CAS Registry Number: 273726-92-4 Chemical Name: 4'-Trifluoromethyl-biphenyl-2-carboxylic acid {4-[4-(5-fluoro-1H-indol-3-ylmethyl)-piperazin-1-yl]-phenyl}amide Linear Structure Formula: C33H28F4N4O Molecular Formula: C33H28F4N4O Molecular Weight: 572.605 InChI Key: FOZRZYXMBRQARJ-UHFFFAOYSA-N Note:

F F

F N N HN

NH O

Reaxys ID 5217660 View in Reaxys HO

172/181 CAS Registry Number: 75410-87-6 Linear Structure Formula: C22H22N4*2C4H4O4 Molecular Formula: 2C4H4O4*C22H22N4 Molecular Weight: 574.59 Type of Substance: heterocyclic InChI Key: UCVXLJPWDABHAA-BTJKTKAUSA-N Note:

2 O

OH NH

N N

Reaxys ID 22690421 View in Reaxys

173/181 Chemical Name: D-429; 6-({2-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]ethyl}propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol tetrahydrochloride Linear Structure Formula: C28H38N4O*4ClH Molecular Formula: C28H38N4O*4ClH Molecular Weight: 592.48 InChI Key: BFOCHSDORYDSCA-UHFFFAOYSA-N Note:

OH 4

N N

HCl

Reaxys ID 12462459 View in Reaxys

174/181

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Linear Structure Formula: C33H33N9OS Molecular Formula: C33H33N9OS Molecular Weight: 603.751 InChI Key: DFIWUWMJFIQXAV-UHFFFAOYSA-N Note:

N N H 2N

N N

Reaxys ID 26222075 View in Reaxys

175/181 Linear Structure Formula: C36H49N7O4 Molecular Formula: C36H49N7O4 Molecular Weight: 643.83 InChI Key: KQWBTESXIVPLNI-CLTPBEKXSA-N Note:

HN O

H N

H 2N O

N H

N N

Reaxys ID 28884180 View in Reaxys

176/181

HN 3 F N

H 2N S

Chemical Name: N6-(2-(4-((5-fluoro-1H-indol-3-yl)methyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine trifluoroacetic acid Linear Structure Formula: C25H35FN6S*3C2HF3O2 Molecular Formula: 3C2HF3O2*C25H35FN6S Molecular Weight: 812.729 InChI Key: JRYRIQZLHDAUMS-UHFFFAOYSA-N Note:

OH F

Reaxys ID 28884191 View in Reaxys

177/181

O O

3 F F

H 2N S

N6-(2-(4-((5-methoxy-1H-indol-3-yl)methyl)-

OH F

Reaxys ID 28884202 View in Reaxys

Chemical Name: piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine Linear Structure Formula: C26H38N6OS*3C2HF3O2 Molecular Formula: 3C2HF3O2*C26H38N6OS Molecular Weight: 824.765 InChI Key: PWNHFSBIYOLUKO-UHFFFAOYSA-N Note:

178/181

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3 F F

Chemical Name: N6-(2-(4-((5-bromo-1H-indol-3-yl)methyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Linear Structure Formula: C25H35BrN6S*3C2HF3O2 Molecular Formula: 3C2HF3O2*C25H35BrN6S Molecular Weight: 873.635 InChI Key: PEOOBDRKXRIHJA-UHFFFAOYSA-N Note:

OH F

H 2N S

Reaxys ID 24253630 View in Reaxys

179/181 Linear Structure Formula: C27H26ClN5O*(x)ClH Molecular Formula: C27H26ClN5O*(x)ClH InChI Key: XNEJSWDOGCZTKT-UHFFFAOYSA-N Note:

HN N -1 HCl

N N Cl N H

Reaxys ID 24253631 View in Reaxys

180/181 Linear Structure Formula: C26H24ClN5*(x)ClH Molecular Formula: C26H24ClN5*(x)ClH InChI Key: AKCDDCBYMGUBNF-UHFFFAOYSA-N Note:

HN N

-1 HCl

Cl HN

Reaxys ID 24253633 View in Reaxys

181/181

Linear Structure Formula: C26H24ClN5O*(x)ClH Molecular Formula: C26H24ClN5O*(x)ClH InChI Key: HKHFDBLPEKODJO-UHFFFAOYSA-N Note:

HN N -1 HCl

N N Cl N H

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