Reaxys
PubChem
eMolecules
Bioactivities (507)
LabNetwork
SigmaAldrich
Reactions (354)
Structure
Substances (181)
Targets (97)
Citations (129)
N° of preparations All Preps | All Reactions
Available Data
Reaxys Registry Number: 27144079
CAS Registry Number: 355823-76-6 Molecular Formula: C23H29N3O3
Linear Structure Formula: C23H29N3O3
Molecular Weight: 395.502
InChI Key: QXQHDEHOKNWVNF-UHFFFAOYSA-N
no reactions.
Reaxys Registry Number: 31173349
Molecular Formula: C23H29N3O3
Linear Structure Formula: C23H29N3O3
Molecular Weight: 395.502
InChI Key: SKTMFTDDYHSSIN-UHFFFAOYSA-N
no reactions.
Structure/Compound Data
Target
N° of ref.
Druglikeness
Bioactivity
Identification
Show Targets
2
Druglikeness
Bioactivity
Identification
Show Targets
1
100
Synthesize | Show Details Find similar
101
Synthesize | Show Details Find similar
Reaxys Registry Number: 12317637
Molecular Formula: C20H24N6O3
Linear Structure Formula: C20H24N6O3
Molecular Weight: 396.449
InChI Key: FEWWLHCFEBYWGW-UHFFFAOYSA-N
1 prep out of 1 reactions.
Druglikeness
Identification Physical Data (1)
Show Targets
1
Chemical Name: [41] N-[3-(4-methylpiperazin-1-yl)methyl-1H-indol-5-yl]-αtoluenesulphonamide
no reactions.
Druglikeness
Bioactivity
Identification Physical Data (1) Spectra (4)
Show Targets
8
1 prep out of 1 reactions.
Druglikeness
Identification Spectra (1)
Show Targets
1
1 prep out of 1 reactions.
Druglikeness
Identification Spectra (4)
Show Targets
1
no reactions.
Bioactivity
Show
2
102
Synthesize | Show Details Find similar
Reaxys Registry Number: 14173459
CAS Registry Number: 528860-17-5 Molecular Formula: C21H26N4O2S Linear Structure Formula: C21H26N4O2S Molecular Weight: 398.529
InChI Key: IOJVMOAYKYBHST-UHFFFAOYSA-N
103
Synthesize | Show Details Find similar Chemical Name: 5-bromo-3-(4-(1-methoxyphen-2-yl)piperazin-1-ylmethyl)-1Hindole Reaxys Registry Number: 11951128
CAS Registry Number: 701205-16-5 Molecular Formula: C20H22BrN3O Linear Structure Formula: C20H22BrN3O Molecular Weight: 400.318
InChI Key: FSGUUQJMURQGAW-UHFFFAOYSA-N
104
Synthesize | Show Details Find similar Chemical Name: 5-bromo-3-{[4-(4-methoxyphenyl)-1-piperazinyl]methyl}-1Hindole Reaxys Registry Number: 22705332
Molecular Formula: C20H22BrN3O Linear Structure Formula: C20H22BrN3O Molecular Weight: 400.318
InChI Key: BYIWJSNUXJJKNX-UHFFFAOYSA-N 105
Synthesize | Show Details Find similar Reaxys Registry Number: 24428086
Molecular Formula: C20H19F3N6
Linear Structure Formula: C20H19F3N6
Molecular Weight: 400.406
Targets
106
Synthesize | Show Details Find similar Reaxys Registry Number: 19332396
CAS Registry Number: 1166813-33-7 Molecular Formula: C19H18F3N7
Linear Structure Formula: C19H18F3N7
Molecular Weight: 401.394
InChI Key: GPTAPLOYDQZRFX-UHFFFAOYSA-N
1 prep out of 1 reactions.
Bioactivity
Identification Spectra (2)
Show Targets
2
Chemical Name: 6-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine
1 prep out of 1 reactions.
Bioactivity
Identification Spectra (2)
Show Targets
2
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
3
no reactions.
Druglikeness
Show
1
107
Synthesize | Show Details Find similar
Reaxys Registry Number: 19332422
CAS Registry Number: 1166811-03-5 Molecular Formula: C19H18F3N7
Linear Structure Formula: C19H18F3N7
Molecular Weight: 401.394
InChI Key: YHGQQKFBDVHQFM-UHFFFAOYSA-N
108
Synthesize | Show Details Find similar Chemical Name: 6-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]-3(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazine Reaxys Registry Number: 20623266
CAS Registry Number: 1240299-43-7 Molecular Formula: C19H20F3N7
Linear Structure Formula: C19H20F3N7
Molecular Weight: 403.41
InChI Key: AUBNKPBCVWTIIG-UHFFFAOYSA-N
109
Synthesize | Show Details Find similar Chemical Name:
5-methanesulfonyl-3-[4-(4-chlorophenyl)piperazin-1yl]methylindole
Identification
Targets
Reaxys Registry Number: 11725015
Molecular Formula: C20H22ClN3O2S Linear Structure Formula: C20H22ClN3O2S Molecular Weight: 403.933
InChI Key: RLQSXVIABFBZGJ-UHFFFAOYSA-N
110
Synthesize | Show Details Find similar Reaxys Registry Number: 19332444
CAS Registry Number: 1166813-28-0 Molecular Formula: C20H18F2N8
Linear Structure Formula: C20H18F2N8
Molecular Weight: 408.413
InChI Key: VHGCZEIQFHAMMD-UHFFFAOYSA-N
1 prep out of 1 reactions.
Bioactivity
Identification Spectra (2)
Show Targets
2
Chemical Name: N-[3-(4-methylpiperazin-1-yl)methyl-1H-indol-5-yl]-trans-βstyrenesulphonamide
no reactions.
Druglikeness
Bioactivity
Identification Physical Data (1) Spectra (4)
Show Targets
8
Reaxys Registry Number: 25292007
Molecular Formula: C22H26N4O2S Linear Structure Formula: C22H26N4O2S Molecular Weight: 410.54
InChI Key: XKJTZDFTSAZUEV-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Chemical Name:
1 prep
Druglikeness
Show
1
111
Synthesize | Show Details Find similar
Reaxys Registry Number: 14173860
CAS Registry Number: 528860-05-1 Molecular Formula: C22H26N4O2S Linear Structure Formula: C22H26N4O2S Molecular Weight: 410.54
InChI Key: JYFZTHMGIJASIF-NTEUORMPSA-N
112
Synthesize | Show Details Find similar
113
Synthesize | Show Details Find similar
1-[(4-Cyano-5-methyl-4-phenyl)hexyl]-4-[(3indolyl)methyl]piperazine
out of 1 reactions.
Bioactivity
Identification Spectra (1)
Targets
Reaxys Registry Number: 25120862
Molecular Formula: C24H22FN5O Linear Structure Formula: C24H22FN5O Molecular Weight: 415.47
InChI Key: BAEVARPPYYAVPQ-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 29891289
Molecular Formula: C25H25FN4O Linear Structure Formula: C25H25FN4O Molecular Weight: 416.498
InChI Key: DPIIFXNAGCUCFF-UHFFFAOYSA-N
no reactions.
Druglikeness
Identification Physical Data (1) Spectra (2)
Show Targets
1
Reaxys Registry Number: 25209760
Molecular Formula: C25H31N5O Linear Structure Formula: C25H31N5O Molecular Weight: 417.554
InChI Key: JHVLNPHVAJOJTR-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
2
Reaxys Registry Number: 19332392
1 prep
Bioactivity
Show
2
Reaxys Registry Number: 15337111
CAS Registry Number: 350850-00-9 Molecular Formula: C27H34N4
Linear Structure Formula: C27H34N4
Molecular Weight: 414.594
InChI Key: AYCOHRNAXUGXCP-UHFFFAOYSA-N
114
Synthesize | Show Details Find similar
115
Synthesize | Show Details Find similar
116
Synthesize | Show Details Find similar
117
Synthesize | Show Details Find similar
CAS Registry Number: 1166813-29-1 Molecular Formula: C19H18ClF2N7
Linear Structure Formula: C19H18ClF2N7
Molecular Weight: 417.849
InChI Key: QXIKGVSTVMMSLI-UHFFFAOYSA-N
out of 1 reactions.
Identification Spectra (2)
Targets
Reaxys Registry Number: 24428089
Molecular Formula: C20H18F4N6
Linear Structure Formula: C20H18F4N6
Molecular Weight: 418.397
no reactions.
Bioactivity
Show Targets
2
Chemical Name: N-methyl-3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]-5indolesulfonamide
no reactions.
Druglikeness
Identification
Show Targets
1
Reaxys Registry Number: 19332482
CAS Registry Number: 1166813-24-6 Molecular Formula: C19H17F4N7
Linear Structure Formula: C19H17F4N7
Molecular Weight: 419.384
InChI Key: KLOXENUKOZCWFV-UHFFFAOYSA-N
1 prep out of 1 reactions.
Bioactivity
Identification Spectra (2)
Show Targets
2
Chemical Name:
2 prep
Druglikeness
Show
3
118
Synthesize | Show Details Find similar
119
Synthesize | Show Details Find similar
Reaxys Registry Number: 11725016
Molecular Formula: C20H23ClN4O2S Linear Structure Formula: C20H23ClN4O2S Molecular Weight: 418.947
InChI Key: QCPPIIFNZUDTSX-UHFFFAOYSA-N
120
Synthesize | Show Details Find similar
121
Synthesize | Show Details Find similar
6-(5-(4-(1H-indol-3-ylmethyl)-piperazin-1-yl)-pyridin-3-yl)isoquinoline
out of 2 reactions.
Bioactivity
Identification Spectra (2)
Targets
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
3
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Physical Data (1)
Show Targets
3
Reaxys Registry Number: 25673014
CAS Registry Number: 1166818-94-5 Molecular Formula: C21H18F3N7
Linear Structure Formula: C21H18F3N7
Molecular Weight: 425.416
InChI Key: GIYGJFXAZCJZHE-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 19332518
1 prep
Bioactivity
Show
2
Reaxys Registry Number: 11752122
Molecular Formula: C27H25N5
Linear Structure Formula: C27H25N5
Molecular Weight: 419.529
InChI Key: SCWIRSFEUFHHKA-UHFFFAOYSA-N
122
Synthesize | Show Details Find similar Chemical Name: 6-{4-[(5-fluoro-1H-indol-3-yl)methyl]piperazin-1-yl}-3(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazine Reaxys Registry Number: 20623282
CAS Registry Number: 1240299-44-8 Molecular Formula: C19H19F4N7
Linear Structure Formula: C19H19F4N7
Molecular Weight: 421.4
InChI Key: WEJKWKWMCGZGBL-UHFFFAOYSA-N
123
Synthesize | Show Details Find similar Chemical Name: N-(4-indol-3-ylmethyl-piperazin-1-yl)-3,4,5-trimethoxybenzamide Reaxys Registry Number: 632470
CAS Registry Number: 58434-19-8 Type of Substance: heterocyclic Molecular Formula: C23H28N4O4
Linear Structure Formula: C23H28N4O4
Molecular Weight: 424.5
InChI Key: MYYUMVOCRJWWIZ-UHFFFAOYSA-N
124
Synthesize | Show Details Find similar
125
Synthesize | Show Details Find similar
CAS Registry Number: 1166813-18-8 Molecular Formula: C20H17F3N8
Linear Structure Formula: C20H17F3N8
Molecular Weight: 426.404
InChI Key: DQEVPJDXAAJOMS-UHFFFAOYSA-N
out of 1 reactions.
Identification Spectra (2)
Targets
Chemical Name: 3-({4-[3-(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3b]pyridazin-6-yl]piperazin-1-yl}methyl)-1H-indole-5carbonitrile
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
3
2 prep out of 2 reactions.
Druglikeness
Identification Physical Data (1) Spectra (2)
Show Targets
1
Reaxys Registry Number: 19332475
CAS Registry Number: 1166813-20-2 Molecular Formula: C19H17ClF3N7
Linear Structure Formula: C19H17ClF3N7
Molecular Weight: 435.839
InChI Key: MZDUDKZZKOVNNE-UHFFFAOYSA-N
1 prep out of 1 reactions.
Bioactivity
Identification Spectra (2)
Show Targets
2
Reaxys Registry Number: 13059875
1 prep
Druglikeness
Show
2
126
Synthesize | Show Details Find similar
Reaxys Registry Number: 20623289
CAS Registry Number: 1240299-45-9 Molecular Formula: C20H19F3N8
Linear Structure Formula: C20H19F3N8
Molecular Weight: 428.42
InChI Key: VOTLZURATNBCQE-UHFFFAOYSA-N
127
Synthesize | Show Details Find similar Chemical Name: 1-benzyl-N-(3-((4-methylpiperazin-1-yl)methyl)-1H-indol-5yl)-1H-pyrazole-4-carboxamide Reaxys Registry Number: 31639373
Molecular Formula: C25H28N6O Linear Structure Formula: C25H28N6O Molecular Weight: 428.537
InChI Key: NOJHMLGDGWPYAT-UHFFFAOYSA-N
128
Synthesize | Show Details Find similar
129
Synthesize | Show Details Find similar
Molecular Formula: C25H26N8
Linear Structure Formula: C25H26N8
Molecular Weight: 438.535
InChI Key: OSDSSWSLYXXJIH-UHFFFAOYSA-N
out of 1 reactions.
Bioactivity
Identification
Targets
Chemical Name: 8-chloro-11-{4-[(1H-indol-3-yl)methyl]piperazino}-5Hdibenzo[b,e][1,4]diazepine
6 prep out of 6 reactions.
Druglikeness
Bioactivity
Identification Physical Data (2) Spectra (5)
Show Targets
2
6 prep out of 6 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
1
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification Physical Data (1) Spectra (5)
Show Targets
2
1 prep
Bioactivity
Show
2
130
Synthesize | Show Details Find similar
Reaxys Registry Number: 9299383
Type of Substance: heterocyclic Molecular Formula: C26H24ClN5
Linear Structure Formula: C26H24ClN5
Molecular Weight: 441.963
InChI Key: XRRJUQKQCOYQDM-UHFFFAOYSA-N
131
Synthesize | Show Details Find similar Chemical Name: 6-({2-[4-(1H-indol-3-ylmethyl)piperazin-1yl]ethyl}propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol Reaxys Registry Number: 22690399
CAS Registry Number: 1381992-14-8 Molecular Formula: C28H38N4O Linear Structure Formula: C28H38N4O Molecular Weight: 446.636
InChI Key: UHRDDHPBSKWWGI-UHFFFAOYSA-N
132
Synthesize | Show Details Find similar Chemical Name: 8-chloro-11-{4-[(5-hydroxy-1H-indol-3yl)methyl]piperazino}-5H-dibenzo[b,e][1,4]diazepine Reaxys Registry Number: 9302328
Type of Substance: heterocyclic Molecular Formula: C26H24ClN5O Linear Structure Formula: C26H24ClN5O Molecular Weight: 457.962
InChI Key: IMTHIGQRYFSTIP-UHFFFAOYSA-N
133
Synthesize | Show Details Find similar Reaxys Registry Number: 19332393
CAS Registry Number: 1166813-31-5 Molecular Formula: C19H18BrF2N7
Linear Structure Formula: C19H18BrF2N7
Molecular Weight: 462.3
InChI Key: DZRBIROXFUGWJH-UHFFFAOYSA-N
out of 1 reactions.
Identification Spectra (2)
Targets
Chemical Name: 2-<2-<4-((5-fluoro-1H-indol-3-yl)methyl)-1piperazinyl>ethyl>-2H-naphth<1,8-cd>isothiazole 1,1-dioxide
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Physical Data (1) Spectra (1)
Show Targets
2
Reaxys Registry Number: 21907482
CAS Registry Number: 1266605-65-5 Molecular Formula: C25H28F2N6O Linear Structure Formula: C25H28F2N6O Molecular Weight: 466.534
InChI Key: QLDMLILLPALAOJ-IQGLISFBSA-N
11 prep out of 11 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
2
Chemical Name: N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)-5(trifluoromethyl)phenyl)furan-2-carboxamide
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
1
1 prep
Druglikeness
Show
1
134
Synthesize | Show Details Find similar
Reaxys Registry Number: 6165617
Type of Substance: heterocyclic Molecular Formula: C25H25FN4O2S Linear Structure Formula: C25H25FN4O2S Molecular Weight: 464.564
InChI Key: VDYVPBAJQCJILV-UHFFFAOYSA-N
135
Synthesize | Show Details Find similar
136
Synthesize | Show Details Find similar
Reaxys Registry Number: 31105801
Molecular Formula: C25H23F3N4O2
Linear Structure Formula: C25H23F3N4O2
Molecular Weight: 468.478
InChI Key: FFLVVHKDKKCYLU-UHFFFAOYSA-N
137
Synthesize | Show Details Find similar Reaxys Registry Number: 12817239
Molecular Formula: C27H33N7O Linear Structure Formula: C27H33N7O Molecular Weight: 471.605
InChI Key: XTXCESRFEUTRRC-VWLOTQADSA-N
out of 1 reactions.
Identification Spectra (1)
Targets
Chemical Name: 8-chloro-11-{4-[(5-methoxy-1H-indol-3yl)methyl]piperazino}-5H-dibenzo[b,e][1,4]diazepine
6 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification Physical Data (2) Spectra (5)
Show Targets
2
Reaxys Registry Number: 12051632
Molecular Formula: C29H27N5O2
Linear Structure Formula: C29H27N5O2
Molecular Weight: 477.566
InChI Key: BMOKEYVONUEXPM-UHFFFAOYSA-N
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (1)
Show Targets
3
Chemical Name: N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)-5(trifluoromethyl)phenyl)picolinamide
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
1
1 prep
Bioactivity
Show
2
138
Synthesize | Show Details Find similar
Reaxys Registry Number: 9301970
CAS Registry Number: 507263-43-6 Type of Substance: heterocyclic Molecular Formula: C27H26ClN5O Linear Structure Formula: C27H26ClN5O Molecular Weight: 471.989
InChI Key: ZRIRCTNRDXEQKJ-UHFFFAOYSA-N
139
Synthesize | Show Details Find similar
140
Synthesize | Show Details Find similar
Reaxys Registry Number: 31105712
Molecular Formula: C26H24F3N5O Linear Structure Formula: C26H24F3N5O Molecular Weight: 479.505
InChI Key: HGUWBZCQIAPPLU-UHFFFAOYSA-N
141
Synthesize | Show Details Find similar Reaxys Registry Number: 19332483
CAS Registry Number: 1166813-22-4 Molecular Formula: C19H17BrF3N7
Linear Structure Formula: C19H17BrF3N7
Molecular Weight: 480.29
InChI Key: JSNIQHXGQRJBCK-UHFFFAOYSA-N
out of 1 reactions.
Identification Spectra (2)
Targets
Reaxys Registry Number: 22432078
CAS Registry Number: 1266605-77-9 Molecular Formula: C26H30F2N6O Linear Structure Formula: C26H30F2N6O Molecular Weight: 480.561
InChI Key: ZEAHDUPFIJMATC-NIYFSFCBSA-N
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 25844291
CAS Registry Number: 1349521-83-0 Molecular Formula: C26H33FN6O2
Linear Structure Formula: C26H33FN6O2
Molecular Weight: 480.585
InChI Key: BZGZNRCUJNTVKR-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Chemical Name: (2R,3R)-2-(2,4-difluorophenyl)-3-[4-(5-fluoro-1H-indol-3ylmethyl)-piperazin-1-yl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification Spectra (3)
Show Targets
1
1 prep
Druglikeness
Show
10
142
Synthesize | Show Details Find similar
143
Synthesize | Show Details Find similar
144
Synthesize | Show Details Find similar
Reaxys Registry Number: 22432084
CAS Registry Number: 1266605-73-5 Molecular Formula: C25H27F3N6O Linear Structure Formula: C25H27F3N6O Molecular Weight: 484.524
InChI Key: VDCDFMWDUGKVSJ-CRICUBBOSA-N
145
Synthesize | Show Details Find similar Chemical Name:
[851] N-[3-(4-methylpiperazin-1-yl)methyl-1H-indol-5-yl]-5chloro-3-methylbenzo[b]thiophene-2-sulphonamide
out of 1 reactions.
Bioactivity
Identification Physical Data (1) Spectra (4)
Targets
Reaxys Registry Number: 22432088
CAS Registry Number: 1266605-82-6 Molecular Formula: C26H27F2N7O Linear Structure Formula: C26H27F2N7O Molecular Weight: 491.543
InChI Key: VNEDIPQYIHKWLB-WXTAPIANSA-N
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 22432085
CAS Registry Number: 1266605-80-4 Molecular Formula: C26H30F2N6O2
Linear Structure Formula: C26H30F2N6O2
Molecular Weight: 496.56
InChI Key: UAFYUKBSJYTLOY-WXTAPIANSA-N
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Chemical Name: 9-(4,5-dimethyl-thiazol-2-yl)-4-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]-5,6,7,8-tetrahydro-1,3,4b-triaza-fluorene
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
1
no reactions.
Druglikeness
Show
1
Reaxys Registry Number: 14181097
CAS Registry Number: 528859-48-5 Molecular Formula: C23H25ClN4O2S2
Linear Structure Formula: C23H25ClN4O2S2
Molecular Weight: 489.062
InChI Key: HYKSBOYHYALPPR-UHFFFAOYSA-N
146
Synthesize | Show Details Find similar
147
Synthesize | Show Details Find similar
148
Synthesize | Show Details Find similar
Reaxys Registry Number: 11992643
CAS Registry Number: 731825-08-4 Molecular Formula: C28H31N7S Linear Structure Formula: C28H31N7S Molecular Weight: 497.667
InChI Key: OHSSKNYHOIZQRB-UHFFFAOYSA-N
149
Synthesize | Show Details Find similar Reaxys Registry Number: 25760769
CAS Registry Number: 1349661-17-1 Molecular Formula: C28H31N7S Linear Structure Formula: C28H31N7S Molecular Weight: 497.667
InChI Key: AMOXTCKQRAEICA-UHFFFAOYSA-N
Bioactivity
Identification
Targets
150
Synthesize | Show Details Find similar Reaxys Registry Number: 22432075
CAS Registry Number: 1266605-75-7 Molecular Formula: C25H27ClF2N6O Linear Structure Formula: C25H27ClF2N6O Molecular Weight: 500.979
InChI Key: VMVQVNNCFZWQTK-CRICUBBOSA-N
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 22432093
CAS Registry Number: 1266605-81-5 Molecular Formula: C25H27F2N9O Linear Structure Formula: C25H27F2N9O Molecular Weight: 507.546
InChI Key: OOYHOUHWHUVJMQ-CRICUBBOSA-N
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 25120863
Molecular Formula: C25H22F6N4O Linear Structure Formula: C25H22F6N4O Molecular Weight: 508.466
InChI Key: CIFOCVBJYGFAPD-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 26087883
no reactions.
Druglikeness
Show
1
151
Synthesize | Show Details Find similar
152
Synthesize | Show Details Find similar
153
Synthesize | Show Details Find similar
Molecular Formula: C2HF3O2*C23H27FN4O Linear Structure Formula: C2HF3O2*C23H27FN4O Molecular Weight: 508.516
InChI Key: XOJZRTVYJDAINI-FSRHSHDFSA-N
Bioactivity
Identification
Targets
154
Synthesize | Show Details Find similar Reaxys Registry Number: 20725055
Molecular Formula: C29H28N6O3
Linear Structure Formula: C29H28N6O3
Molecular Weight: 508.58
InChI Key: ZCIAWRZDKXSETI-UHFFFAOYSA-N
1 prep out of 1 reactions.
Druglikeness
Identification Spectra (1)
Show Targets
1
Reaxys Registry Number: 22432087
CAS Registry Number: 1266605-83-7 Molecular Formula: C26H29F2N7O2
Linear Structure Formula: C26H29F2N7O2
Molecular Weight: 509.559
InChI Key: XWNWLUXBJDZSEX-WXTAPIANSA-N
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 22432091
CAS Registry Number: 1266605-79-1 Molecular Formula: C25H27F2N7O3
Linear Structure Formula: C25H27F2N7O3
Molecular Weight: 511.531
InChI Key: FAGHMIXGHHCEPF-CRICUBBOSA-N
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Chemical Name:
4 prep
Druglikeness
Show
1
155
Synthesize | Show Details Find similar
156
Synthesize | Show Details Find similar
157
Synthesize | Show Details Find similar
methyl (Z)-3-(((3-((4-methylpiperazin-1-yl)methyl)-1H-indol5-yl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
out of 4 reactions.
Bioactivity
Identification Physical Data (2) Spectra (3)
Targets
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
2
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
2
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (2)
Show Targets
2
no reactions.
Druglikeness
Show
1
Reaxys Registry Number: 31558258
Molecular Formula: C31H31N5O3
Linear Structure Formula: C31H31N5O3
Molecular Weight: 521.619
InChI Key: XNLAEVVAFHZWEB-ZIADKAODSA-N
158
Synthesize | Show Details Find similar Chemical Name: 1-(4-{5-[6-amino-5-(2,6-dichloro-benzyloxy)-pyridin-3-yl]-1Hindol-3-ylmethyl}-piperazin-1-yl)-ethanone Reaxys Registry Number: 12065107
Molecular Formula: C27H27Cl2N5O2
Linear Structure Formula: C27H27Cl2N5O2
Molecular Weight: 524.45
InChI Key: OYACPHQVNCYSTD-UHFFFAOYSA-N
159
Synthesize | Show Details Find similar Chemical Name: 1-(4-{5-[6-amino-5-(2-chloro-3,6-difluoro-benzyloxy)-pyridin3-yl]-1H-indol-3-ylmethyl}-piperazin-1-yl)-ethanone Reaxys Registry Number: 12065459
Molecular Formula: C27H26ClF2N5O2
Linear Structure Formula: C27H26ClF2N5O2
Molecular Weight: 525.986
InChI Key: IFALZBXDPWLSSQ-UHFFFAOYSA-N
160
Synthesize | Show Details Find similar Chemical Name: 1-(4-{5-[5-amino-6-(2-chloro-3,6-difluoro-benzyloxy)-pyrazin2-yl]-1H-indol-3-ylmethyl}-piperazin-1-yl)-ethanone Reaxys Registry Number: 12065502
Molecular Formula: C26H25ClF2N6O2
Linear Structure Formula: C26H25ClF2N6O2
Molecular Weight: 526.973
InChI Key: WREGOQQTMQTCDW-UHFFFAOYSA-N
161
Synthesize | Show Details Find similar Reaxys Registry Number: 26194769
Molecular Formula: C28H30F2N6O3
Linear Structure Formula: C28H30F2N6O3
Molecular Weight: 536.581
InChI Key: BYDDVYPSKQEEAJ-UQDIGLKLSA-N
Bioactivity
Identification
Targets
162
Synthesize | Show Details Find similar Reaxys Registry Number: 22432082
CAS Registry Number: 1266605-76-8 Molecular Formula: C25H27BrF2N6O Linear Structure Formula: C25H27BrF2N6O Molecular Weight: 545.43
InChI Key: IQNKQOUNDLEETD-CRICUBBOSA-N
7 prep out of 7 reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Chemical Name: N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)-5(trifluoromethyl)phenyl)-5-(pyridin-4-yl)furan-2-carboxamide
1 prep out of 1 reactions.
Druglikeness
Bioactivity
Identification Spectra (4)
Show Targets
2
no reactions.
Druglikeness
Bioactivity
Identification Spectra (1)
Show Targets
1
no reactions.
Druglikeness
Show
1
163
Synthesize | Show Details Find similar
Reaxys Registry Number: 28817958
Molecular Formula: C30H26F3N5O2
Linear Structure Formula: C30H26F3N5O2
Molecular Weight: 545.564
InChI Key: PXTGGKHRMSAKSB-UHFFFAOYSA-N
164
Synthesize | Show Details Find similar Chemical Name: 3-{4-[[1-(2,6-dimethylphenyl)-1H-tetrazol-5-yl]-(3trifluoromethylphenyl)methyl]piperazin-1-ylmethyl}-1H-indole Reaxys Registry Number: 12251232
Molecular Formula: C30H30F3N7
Linear Structure Formula: C30H30F3N7
Molecular Weight: 545.61
InChI Key: CKAZCJFSWDKTAZ-UHFFFAOYSA-N
165
Synthesize | Show Details Find similar Reaxys Registry Number: 25024367
Molecular Formula: C30H30F3N7
Linear Structure Formula: C30H30F3N7
Molecular Weight: 545.61
InChI Key: CKAZCJFSWDKTAZ-NDEPHWFRSA-N
Bioactivity
Identification
Targets
166
Synthesize | Show Details Find similar Reaxys Registry Number: 22981168
CAS Registry Number: 1403360-01-9 Molecular Formula: C27H27F3N6O4
Linear Structure Formula: C27H27F3N6O4
Molecular Weight: 556.544
InChI Key: PRQPTJGEDHERPW-UHFFFAOYSA-N
1 prep out of 1 reactions.
Druglikeness
Identification Spectra (1)
Show Targets
1
Chemical Name: 1,4-bis-(5-benzyloxy-indol-3-ylmethyl)-piperazine
1 prep out of 1 reactions.
Druglikeness
Identification Physical Data (1)
Show Targets
1
5 prep out of 5 reactions.
Druglikeness
Bioactivity
Identification Physical Data (3) Spectra (5)
Show Targets
1
1 prep
Druglikeness
Show
1
167
Synthesize | Show Details Find similar
Reaxys Registry Number: 380252
CAS Registry Number: 103401-68-9 Type of Substance: heterocyclic Molecular Formula: C36H36N4O2
Linear Structure Formula: C36H36N4O2
Molecular Weight: 556.707
InChI Key: CGCRHVIYJGBKHL-UHFFFAOYSA-N
168
Synthesize | Show Details Find similar Chemical Name: 4-{4-[(4-((1H-indol-3-yl)methyl)piperazin-1-yl)methyl]-1H1,2,3-triazol-1-yl}-2,8-bis(trifluoromethyl)quinoline Reaxys Registry Number: 27604342
Molecular Formula: C27H23F6N7
Linear Structure Formula: C27H23F6N7
Molecular Weight: 559.517
InChI Key: MPXYFBKYQYXTLZ-UHFFFAOYSA-N
169
Synthesize | Show Details Find similar Reaxys Registry Number: 12637634
Molecular Formula: C31H40FN7O2
Linear Structure Formula: C31H40FN7O2
Molecular Weight: 561.703
InChI Key: QXDUUKULQWPOKB-UHFFFAOYSA-N
out of 1 reactions.
Bioactivity
Identification
Targets
Chemical Name: 4'-Trifluoromethyl-biphenyl-2-carboxylic acid {4-[4-(5-fluoro1H-indol-3-ylmethyl)-piperazin-1-yl]-phenyl}-amide
1 prep out of 1 reactions.
Druglikeness
Identification
Show Targets
1
Reaxys Registry Number: 5217660
CAS Registry Number: 75410-87-6 Type of Substance: heterocyclic Molecular Formula: 2C4H4O4*C22H22N4
Linear Structure Formula: C22H22N4*2C4H4O4
Molecular Weight: 574.59
InChI Key: UCVXLJPWDABHAA-BTJKTKAUSA-N
no reactions.
Druglikeness
Bioactivity
Identification Physical Data (1)
Show Targets
1
Chemical Name: D-429
no reactions.
Druglikeness
Bioactivity
Identification Physical Data (1)
Show Targets
1
1 prep
Druglikeness
Show
1
170
Synthesize | Show Details Find similar
Reaxys Registry Number: 14142573
CAS Registry Number: 273726-92-4 Molecular Formula: C33H28F4N4O Linear Structure Formula: C33H28F4N4O Molecular Weight: 572.605
InChI Key: FOZRZYXMBRQARJ-UHFFFAOYSA-N
171
Synthesize | Show Details Find similar
172
Synthesize | Show Details Find similar
Reaxys Registry Number: 22690421
Molecular Formula: C28H38N4O*4ClH Linear Structure Formula: C28H38N4O*4ClH Molecular Weight: 592.48
InChI Key: BFOCHSDORYDSCA-UHFFFAOYSA-N
173
Synthesize | Show Details Find similar Reaxys Registry Number: 12462459
Molecular Formula: C33H33N9OS Linear Structure Formula: C33H33N9OS Molecular Weight: 603.751
InChI Key: DFIWUWMJFIQXAV-UHFFFAOYSA-N
out of 1 reactions.
Identification Spectra (1)
Targets
Reaxys Registry Number: 26222075
Molecular Formula: C36H49N7O4
Linear Structure Formula: C36H49N7O4
Molecular Weight: 643.83
InChI Key: KQWBTESXIVPLNI-CLTPBEKXSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Chemical Name: N6-(2-(4-((5-fluoro-1H-indol-3-yl)methyl)piperazin-1-yl)ethyl)N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine trifluoroacetic acid
3 prep out of 3 reactions.
Druglikeness
Bioactivity
Identification Physical Data (1) Spectra (2)
Show Targets
1
2 prep out of 2 reactions.
Druglikeness
Bioactivity
Identification Physical Data (1) Spectra (2)
Show Targets
1
2 prep
Druglikeness
Show
1
174
Synthesize | Show Details Find similar
175
Synthesize | Show Details Find similar
Reaxys Registry Number: 28884180
Molecular Formula: 3C2HF3O2*C25H35FN6S Linear Structure Formula: C25H35FN6S*3C2HF3O2
Molecular Weight: 812.729
InChI Key: JRYRIQZLHDAUMS-UHFFFAOYSA-N
176
Synthesize | Show Details Find similar Chemical Name: N6-(2-(4-((5-methoxy-1H-indol-3-yl)methyl)-piperazin-1yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6diamine Reaxys Registry Number: 28884191
Molecular Formula: 3C2HF3O2*C26H38N6OS Linear Structure Formula: C26H38N6OS*3C2HF3O2
Molecular Weight: 824.765
InChI Key: PWNHFSBIYOLUKO-UHFFFAOYSA-N
177
Synthesize | Show Details Find similar Chemical Name:
N6-(2-(4-((5-bromo-1H-indol-3-yl)methyl)piperazin-1-yl)ethyl)N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
out of 2 reactions.
Bioactivity
Identification Spectra (1)
Targets
Reaxys Registry Number: 24253630
Molecular Formula: C27H26ClN5O*(x)ClH Linear Structure Formula: C27H26ClN5O*(x)ClH InChI Key: XNEJSWDOGCZTKT-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 24253631
Molecular Formula: C26H24ClN5*(x)ClH Linear Structure Formula: C26H24ClN5*(x)ClH InChI Key: AKCDDCBYMGUBNF-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 24253633
Molecular Formula: C26H24ClN5O*(x)ClH Linear Structure Formula: C26H24ClN5O*(x)ClH InChI Key: HKHFDBLPEKODJO-UHFFFAOYSA-N
no reactions.
Druglikeness
Bioactivity
Identification
Show Targets
1
Reaxys Registry Number: 28884202
Molecular Formula: 3C2HF3O2*C25H35BrN6S Linear Structure Formula: C25H35BrN6S*3C2HF3O2
Molecular Weight: 873.635
InChI Key: PEOOBDRKXRIHJA-UHFFFAOYSA-N
178
Synthesize | Show Details Find similar
179
Synthesize | Show Details Find similar
180
Synthesize | Show Details Find similar
181
Synthesize | Show Details Find similar