Reaxys
PubChem
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LabNetwork
Bioactivities (2811)
SigmaAldrich
Reactions (1573)
Substances (1)
Targets (176)
Structure
Citations (7114)
N° of preparations All Preps | All Reactions
Structure/Compound Data Chemical Name: 3,4,5-trihydroxybenzoic acid
274 prep out of 1573 reactions.
Reaxys Registry Number: 2050274
CAS Registry Number: 149-91-7 Type of Substance: isocyclic Molecular Formula: C7H6O5
Linear Structure Formula: C6H2(OH)3COOH Molecular Weight: 170.122 InChI Key: LNTHITQWFMADLM-UHFFFAOYSA-N
1
Available Data
Target
N° of ref.
Druglikeness
Bioactivity
Identification Physical Data (563) Spectra (428) Other Data (1122)
Show Targets
7114
Synthesize | Hide Details Find similar Chemical Names and Synonyms 3,4,5-trihydroxybenzoic acid, gallic acid, 3,4,5-Trihydroxybenzoic acid Druglikeness Bioactivity In vitro: Efficacy (1828) Quantitative Results pX
Parameter
4.4
IC50
Value (qual)
Value (quant)
Unit
40
µM
Action on Target
Target enzyme:Wild
Tissue/Organ
Cell
Bioassay In Vitro (others)
Dose
Effect
Reference (expand all/collapse all) Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Kato, Yoji; Nagao, Akihiko; Terao, Junji; Osawa, Toshihiko
Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 5 p. 1136 - 1139 Title/Abstract Full Text Show Details
5.03
IC50
1.6
µg/mL
In Vitro (others)
Antineoplastic
Fitoterapia, 2011 , vol...
Title/Abstract Full Text View citing articles Show Details
In Vitro (others)
Antineoplastic
Fitoterapia, 2011 , vol...
Title/Abstract Full Text View citing articles Show Details
In Vitro (others)
Antioxidant
Phytochemistry, 2010 , ...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
Phytochemistry, 2010 , ...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.
Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details
4.71
IC50
3.3
µg/mL
Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.
Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details
5.49
IC50
3.24
µM
Pfundstein, Beate; El Desouky, Samy K.; Hull, William E.; Haubner, Roswitha; Erben, Gerhard; Owen, Robert W.
Phytochemistry, 2010 , vol. 71, # 10 p. 1132 - 1148 Title/Abstract Full Text View citing articles Show Details
EC1
170
µM
In Vitro (others)
Pfundstein, Beate; El Desouky, Samy K.; Hull, William E.; Haubner, Roswitha; Erben, Gerhard; Owen, Robert W.
Phytochemistry, 2010 , vol. 71, # 10 p. 1132 - 1148 Title/Abstract Full Text View citing articles Show Details
4.96
EC50
1.85
µg/mL
In Vitro (others)
0.00500000 µg/mL
Mazimba, Ofentse; Majinda, Runner R.T.; Modibedi, Ceciliah; Masesane, Ishmael B.; Cencic, Avrelija; Chingwaru, Walter
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 17 p. 5225 - 5230 Title/Abstract Full Text View citing articles Show Details
4.3
IC50
49.9
µM
Patent: US2010/137249 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Wang, Binghe; Ni, Nanting; Wang, Junfeng; Lu, Chung-Dar; Chou, Han-Ting; Li, Minyong; Zheng, Shilong; Cheng, Yunfeng; Peng, Hanjing
Patent: US2010/137249 A1, 2010 ; Title/Abstract Full Text Show Details
2.47
IC50
574.2
µg/mL
lipase:Wild
Enzymology inhibition
enzyme [carp]:Wild
In Vitro (others)
Patent: US2011/263698 ...
Title/Abstract Full Text Show Details
NICHIREI BIOSCIENCES, INC.
Patent: US2011/263698 A1, 2011 ; Title/Abstract Full Text Show Details
3.5
IC50
0.316
mM
0.100000 µM
Bulletin of Environmenta...
Title/Abstract Full Text View citing articles Show Details
Varanka; Szegletes; NemcsoI k; AI brahaI m
Bulletin of Environmental Contamination and Toxicology, 1999 , vol. 63, # 6 p. 751 - 758 Title/Abstract Full Text View citing articles Show Details
3.83
EC50
25
mg/L
In Vitro (others)
Antiparasitic
Planta Medica, 2001 , v...
Title/Abstract Full Text View citing articles Show Details
In Vitro
Antiparasitic
Planta Medica, 2001 , v...
Kolodziej; Kayser; Kiderlen; Ito; Hatano; Yoshida; Foo
Planta Medica, 2001 , vol. 67, # 9 p. 825 - 832 Title/Abstract Full Text View citing articles Show Details
4.59
EC50
4.4
mg/L
(others)
Title/Abstract Full Text View citing articles Show Details
Kolodziej; Kayser; Kiderlen; Ito; Hatano; Yoshida; Foo
Planta Medica, 2001 , vol. 67, # 9 p. 825 - 832 Title/Abstract Full Text View citing articles Show Details
4.04
EC50
15.6
mg/L
In Vitro (others)
Cytotoxic
Planta Medica, 2001 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej; Kayser; Kiderlen; Ito; Hatano; Yoshida; Foo
Planta Medica, 2001 , vol. 67, # 9 p. 825 - 832 Title/Abstract Full Text View citing articles Show Details
5.3
IC50
5
µM
In Vitro (others)
0.0200000 µM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Maggi-Capeyron; Ceballos; Cristol; Delbosc; Le Doucen; Pons; Leger; Descomps
Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 11 p. 5646 - 5652 Title/Abstract Full Text View citing articles Show Details
5.17
EC50
6.83
µM
In Vitro (others)
Antioxidant
Journal of the Brazilian...
Title/Abstract Full Text View citing articles Show Details
Lianda, Regina L. P.; Sant'ana, Luiza D'Oliveira; Echevarria, Aurea; Castro, Rosane N.
Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 4 p. 618 - 627 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
200
µM
fatty acid synthase [chicken]:Wild
Enzymology inhibition
Journal of the Brazilian...
Title/Abstract Full Text View citing articles Show Details
Jiang, He-Zhong; Ma, Qing-Yun; Fan, Hui-Jin; Liang, Wen-Juan; Huang, Sheng-Zhuo; Dai, Hao-Fu; Wang, Peng-Cheng; Ma, Xiao-Feng; Zhao, You-Xing
Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 5 p. 889 - 893 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
16.2
%
In Vitro (others)
500 µM
Antioxidant
Journal of Inorganic Bio...
Title/Abstract Full Text View citing articles Show Details
Perron, Nathan R.; Garcia, Carla R.; Pinzon, Julio R.; Chaur, Manuel N.; Brumaghim, Julia L.
Journal of Inorganic Biochemistry, 2011 , vol. 105, # 5 p. 745 - 753 Title/Abstract Full Text View citing articles Show Details
2.11
% Inhibition
42.9
%
neutrophil
In Vitro (others)
1000 µg/mL
Antiinflammatory
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Ngoumfo, Rostand Manfouo; Ngounou, Georges Eric; Tchamadeu, Chimene Victoire; Qadir, Muhammad Irfan; Mbazoa, Celine Djama; Begum, Afshan; Ngninzeko, Fernande Ngounou; Lontsi, David; Choudhary, Muhammad Iqbal
Journal of Natural Products, 2008 , vol. 71, # 11 p. 1906 - 1910 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1000
µg/mL
neutrophil
In Vitro (others)
Antiinflammatory
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Ngoumfo, Rostand Manfouo; Ngounou, Georges Eric; Tchamadeu, Chimene Victoire; Qadir, Muhammad Irfan; Mbazoa, Celine Djama; Begum, Afshan; Ngninzeko, Fernande Ngounou; Lontsi, David; Choudhary, Muhammad Iqbal
Journal of Natural Products, 2008 , vol. 71, # 11 p. 1906 - 1910 Title/Abstract Full Text View citing articles Show Details
4.95
EC50
0.0019
mg/mL
In Vitro (others)
Antioxidant
Carbohydrate Research, 2...
Title/Abstract Full Text View citing articles Show Details
Pasanphan, Wanvimol; Buettner, Garry R.; Chirachanchai, Suwabun
Carbohydrate Research, 2010 , vol. 345, # 1 p. 132 - 140 Title/Abstract Full Text View citing articles Show Details
4.79
IC50
16.07
µM
In Vitro (others)
Antioxidant
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Park, Kwan Hee; Kim, Sung Kyu; Choi, Sun Eun; Kwon, Joo Hee; Oh, Myung Hwan; Lee, Min Won
Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 9 p. 1227 - 1231 Title/Abstract Full Text View citing articles Show Details
pX
Parameter % Inhibition
Value (qual)
Value (quant)
Unit
23.36
µM
Action on Target
Target
Tissue/Organ
Cell
Bioassay
RAW 264.7 cell line
In Vitro (others)
Dose
Effect
Reference (expand all/collapse all) Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Park, Kwan Hee; Kim, Sung Kyu; Choi, Sun Eun; Kwon, Joo Hee; Oh, Myung Hwan; Lee, Min Won
Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 9 p. 1227 - 1231 Title/Abstract Full Text View citing articles Show Details
ED50
16
µg
Hyaluronidase:Wild
Enzymology inhibition
Antidote
Molecules (Basel, Switze...
Title/Abstract Full Text Show Details
Enzymology inhibition
Antidote
Molecules (Basel, Switze...
Title/Abstract Full Text Show Details
Enzymology inhibition
Antidote
Molecules (Basel, Switze...
Title/Abstract Full Text Show Details
Enzymology inhibition
Antidote
Molecules (Basel, Switze...
Title/Abstract Full Text Show Details
In Vitro (others)
Antidote
Molecules (Basel, Switze...
Title/Abstract Full Text Show Details
In Vitro (others)
Antidote
Molecules (Basel, Switze...
Title/Abstract Full Text Show Details
Enzymology inhibition
Antidiabetic
Chemistry of Natural Com...
Title/Abstract Full Text View citing articles Show Details
In Vitro (others)
Antioxidant
Chemistry of Natural Com...
Title/Abstract Full Text View citing articles Show Details
Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart
Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details
ED50
14.8
µg
Hyaluronidase:Wild
Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart
Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details
ED50
1.7
µg
Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart
Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details
ED50
4.5
µg
Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart
Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details
ED50
66
µg
phospholipase A2:Wild
Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart
Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details
ED50
123.5
µg
phospholipase A2:Wild
Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart
Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details
4.61
IC50
24.3
µM
alphaglucosidase:Wild
Zhao, Jun; Zhou, Xuan-Wei; Chen, Xiao-Bin; Wang, Quan-Xi
Chemistry of Natural Compounds, 2009 , vol. 45, # 2 p. 244 - 246 Title/Abstract Full Text View citing articles Show Details
5.19
IC50
6.47
µM
Si, Chuan-Ling; Zhang, Yu; Zhu, Zhen-Yuan; Liu, Shi-Chao
Chemistry of Natural Compounds, 2011 , vol. 47, # 3 p. 442 - 445
Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µg/mL
Enzymology inhibition
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Ngamukote, Sathaporn; Maekynen, Kittana; Thilawech, Thavaree; Adisakwattana, Sirichai
Molecules, 2011 , vol. 16, # 6 p. 5054 - 5061 Title/Abstract Full Text View citing articles Show Details
% Stimulation
@
Agonist
Beta-arrestin2:Chimera + G-protein coupled receptor 35 [human]:Chimera
U-2 OS
Protein interaction
Patent: WO2013/22740 A...
Title/Abstract Full Text Show Details
Enzymology inhibition
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
CORNING INCORPORATED; DENG, Huayun; FANG, Ye; HU, Haibei
Patent: WO2013/22740 A2, 2013 ; Title/Abstract Full Text Show Details
3.31
IC50
487
µM
Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild
Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details
3.58
Ki
264
µM
Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild
Enzymology inhibition
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details
3.14
% Inhibition
57.8
%
Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild
Enzymology inhibition
1000 µM
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
12.9
%
Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild
Enzymology inhibition
10 µM
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details
3.69
% Inhibition
33
%
Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild
Enzymology inhibition
100 µM
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details
3.89
EC50
128
µM
Peroxisome proliferator-activated receptor, gamma:Wild
In Vitro (others)
Patent: US2008/131534 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Melbrosin International Produktions- und Vertriebs GesmbH and Co KG
Patent: US2008/131534 A1, 2008 ; Title/Abstract Full Text Show Details
4
IC50
100
µM
enzyme:Wild + Reverse transcriptase [Human immunodeficiency virus]:Wild
Misra, Anju P.; Mathad, Vijayavitthal T.; Raj, Kanwal; Bhaduri, Amiya P.; Tiwari, Rashmi; Srivastava, Anuradha; Mehrotra
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 21 p. 2763 - 2772 Title/Abstract Full Text View citing articles Show Details
4.3
% Inhibition
25 - 50
%
CDK5/Cyclin (p35):Wild + CDK5/Cyclin (CDK5):Wild
Enzymology inhibition
30 µM
Patent: WO2011/69334 A...
Title/Abstract Full Text Show Details
Patent: WO2011/69334 A...
Title/Abstract Full Text Show Details
Patent: WO2011/69334 A...
Title/Abstract Full Text Show Details
Patent: WO2011/69334 A...
Title/Abstract Full Text Show Details
Immunosuppressant
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; IP, Nancy Yuk-Yu; IP, Fanny Chui-Fun; FU, Wing Yu; FU, Guangmiao
Patent: WO2011/69334 A1, 2011 ; Title/Abstract Full Text Show Details
4.3
% Inhibition
25 - 50
%
CDK5/Cyclin (p25):Wild + CDK5/Cyclin (CDK5):Wild
Enzymology inhibition
30 µM
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; IP, Nancy Yuk-Yu; IP, Fanny Chui-Fun; FU, Wing Yu; FU, Guangmiao
Patent: WO2011/69334 A1, 2011 ; Title/Abstract Full Text Show Details
4.39
IC50
40.6
µM
CDK5/Cyclin (p25):Wild + CDK5/Cyclin (CDK5):Wild
Enzymology inhibition
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; IP, Nancy Yuk-Yu; IP, Fanny Chui-Fun; FU, Wing Yu; FU, Guangmiao
Patent: WO2011/69334 A1, 2011 ; Title/Abstract Full Text Show Details
3.95
% Inhibition
64.19
%
CDK5/Cyclin (p25):Wild + CDK5/Cyclin (CDK5):Wild
Enzymology inhibition
200 µM
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; IP, Nancy Yuk-Yu; IP, Fanny Chui-Fun; FU, Wing Yu; FU, Guangmiao
Patent: WO2011/69334 A1, 2011 ; Title/Abstract Full Text Show Details
1.52
IC50
30
mM
In Vitro (others)
0 mM
Hamada, Shin-Ichi; Kataoka, Takao; Woo, Je-Tae; Yamada, Atsushi; Yoshida, Takashi; Nishimura, Toshio; Otake, Noboru; Nagai, Kazuo
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 9 p. 1017 - 1019 Title/Abstract Full Text View citing articles Show Details
4
MIC
100
µM
In Vitro (others)
Toxic
Bulletin of Environmenta...
Title/Abstract Full Text View citing articles Show Details
Schrader; Harries
Bulletin of Environmental Contamination and Toxicology, 2001 , vol. 66, # 6 p. 801 - 807 Title/Abstract Full Text View citing articles Show Details
3
MIC
1000
µM
In Vitro (others)
Toxic
Bulletin of Environmenta...
Title/Abstract Full Text View citing articles Show Details
Schrader; Harries
Bulletin of Environmental Contamination and Toxicology, 2001 , vol. 66, # 6 p. 801 - 807 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1000
mg/L
In Vitro (others)
Bacteriostatic
Planta Medica, 1999 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel
Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
500
mg/L
In Vitro (others)
Bacteriostatic
Planta Medica, 1999 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel
Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details
1.93
MIC
2000
mg/L
In Vitro (others)
Bacteriostatic
Planta Medica, 1999 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel
Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
500
mg/L
In Vitro (others)
Bacteriostatic
Planta Medica, 1999 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel
Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
500
mg/L
In Vitro (others)
Bacteriostatic
Planta Medica, 1999 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel
Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
500
mg/L
In Vitro (others)
Bacteriostatic
Planta Medica, 1999 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel
Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
250
mg/L
In Vitro (others)
Fungistatic
Planta Medica, 1999 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel
Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1000
mg/L
In Vitro (others)
Fungistatic
Planta Medica, 1999 , v...
Title/Abstract Full Text View citing articles Show Details
Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel
Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details
3
IC50
1000
µM
In Vitro (others)
30 µM
Mutagenic
Mutation Research - Fund...
Title/Abstract Full Text View citing articles Show Details
Armstrong; Galloway
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1997 , vol. 373, # 2 p. 167 - 178 Title/Abstract Full Text View citing articles Show Details
5.09
IC50
8.2
µM
In Vitro (others)
1 µM
Planta Medica, 2007 , v...
Title/Abstract Full Text View citing articles Show Details
Mi, Kyeong Lee; Hee, Young Jeon; Ki, Yong Lee; Seung, Hyun Kim; Choong, Je Ma; Sang, Hyun Sung; Lee, Heum-Sook; Mi, Jung Park; Young, Choong Kim
Planta Medica, 2007 , vol. 73, # 8 p. 782 - 786 Title/Abstract Full Text View citing articles Show Details
5.3
EC50
5
µM
In Vitro (others)
Antibiotic
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Srivastava, Vandana; Darokar, Mahendra P.; Fatima, Atiya; Kumar; Chowdhury, Chinmay; Saxena, Hari Om; Dwivedi, Gaurav R.; Shrivastava, Kunal; Gupta, Vivek; Chattopadhyay; Luqman, Suaib; Gupta; Negi, Arvind S.; Khanuja, Suman P.S.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 518 - 525 Title/Abstract Full Text View citing articles Show Details
5.3
EC50
5
µM
In Vitro (others)
Antibiotic
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Srivastava, Vandana; Darokar, Mahendra P.; Fatima, Atiya; Kumar; Chowdhury, Chinmay; Saxena, Hari Om; Dwivedi, Gaurav R.; Shrivastava, Kunal; Gupta, Vivek; Chattopadhyay; Luqman, Suaib; Gupta; Negi, Arvind S.;
Khanuja, Suman P.S.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 518 - 525 Title/Abstract Full Text View citing articles Show Details
5.17
IC50
6.828
µM
glycogen phosphorylase:Wild
In Vitro (others)
Planta Medica, 2008 , v...
Title/Abstract Full Text View citing articles Show Details
Li, Jun; Lu, Yuanyuan; Su, Xiaojian; Li, Fu; She, Zhigang; He, Xingcun; Lin, Yongcheng
Planta Medica, 2008 , vol. 74, # 3 p. 287 - 289 Title/Abstract Full Text View citing articles Show Details
5.33
IC50
4.673
µM
alphaglucosidase:Wild
In Vitro (others)
Planta Medica, 2008 , v...
Title/Abstract Full Text View citing articles Show Details
Li, Jun; Lu, Yuanyuan; Su, Xiaojian; Li, Fu; She, Zhigang; He, Xingcun; Lin, Yongcheng
Planta Medica, 2008 , vol. 74, # 3 p. 287 - 289 Title/Abstract Full Text View citing articles Show Details
3.95
IC50
112
µM
alphaglucosidase:Wild
Enzymology inhibition
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Sancheti, Shruti; Sancheti, Sandesh; Bafna, Mayur; Seo, Sung-Yum
Medicinal Chemistry Research, 2011 , vol. 20, # 8 p. 1181 - 1187 Title/Abstract Full Text View citing articles Show Details
Km
0
mM
Polyphenol oxidase:Wild
Enzymology substrate
Food Chemistry, 2011 , ...
Title/Abstract Full Text View citing articles Show Details
Altunkaya, Arzu
Food Chemistry, 2011 , vol. 128, # 3 p. 754 - 760 Title/Abstract Full Text View citing articles Show Details
Vmax
0
min-1
Polyphenol oxidase:Wild
Enzymology substrate
Food Chemistry, 2011 , ...
Title/Abstract Full Text View citing articles Show Details
Altunkaya, Arzu
Food Chemistry, 2011 , vol. 128, # 3 p. 754 - 760 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1000
µg/mL
Alpha amylase:Wild
Enzymology inhibition
Journal of Natural Medic...
Title/Abstract Full Text View citing articles Show Details
Ochir, Sarangowa; Nishizawa, Makoto; Jae Park, Byoung; Ishii, Kouta; Kanazawa, Tsutomu; Funaki, Minoru; Yamagishi, Takashi
Journal of Natural Medicines, 2010 , vol. 64, # 3 p. 275 - 280 Title/Abstract Full Text View citing articles Show Details
3.08
IC50
143
µg/mL
alphaglucosidase:Wild
Enzymology inhibition
Journal of Natural Medic...
Title/Abstract Full Text View citing articles Show Details
Ochir, Sarangowa; Nishizawa, Makoto; Jae Park, Byoung; Ishii, Kouta; Kanazawa, Tsutomu; Funaki, Minoru; Yamagishi, Takashi
Journal of Natural Medicines, 2010 , vol. 64, # 3 p. 275 - 280 Title/Abstract Full Text View citing articles Show Details
1.93
MBC
2
mg/mL
In Vitro (others)
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
ZI
24
mm
In Vitro (others)
1.50000 mg
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1
mg/mL
In Vitro (others)
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
1.93
MBC
2
mg/mL
In Vitro (others)
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
ZI
25
mm
In Vitro (others)
1.50000 mg
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1
mg/mL
In Vitro (others)
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
1.63
MBC
4
mg/mL
In Vitro (others)
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
ZI
22
mm
In Vitro (others)
1.50000 mg
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
1.93
MIC
2
mg/mL
In Vitro (others)
Antimicrobial
Journal of Molecular Cat...
Title/Abstract Full Text View citing articles Show Details
Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
RAW 264.7 cell line
In Vitro (others)
Antiinflammatory
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Yang, Zhi-Gang; Jia, Liu-Nan; Shen, Yan; Ohmura, Atsuko; Kitanaka, Susumu
Molecules, 2011 , vol. 16, # 10 p. 8305 - 8318 Title/Abstract Full Text View citing articles Show Details
3.78
% Inhibition
37.4
%
Angiotensinconverting enzyme:Wild
Enzymology inhibition
100 µM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
500
µM
Angiotensinconverting enzyme:Wild
Enzymology inhibition
100 µM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details
3.07
% Inhibition
41.1
%
Neprilysin:Wild
Enzymology inhibition
100 µg/mL
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details
3.32
IC50
480
µM
Neprilysin:Wild
Enzymology inhibition
100 µg/mL
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details
5.55
IC50
2.8
µM
neutrophil
Flux release
5 µg/mL
Antiinflammatory
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details
5.38
IC50
4.2
µM
neutrophil
In Vitro (others)
0.200000 µg/mL
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details
3.48
% Stimulation
63.71
%
Agonist
estrogen receptor [human]:Wild
MVLN cell line
Transactivation assay
100 µg/mL
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Liu, Li; Ma, Hongyue; Tang, Yuping; Chen, Wenxing; Lu, Yin; Guo, Jianming; Duan, Jin-Ao
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 154 - 163 Title/Abstract Full Text View citing articles Show Details
5
% Stimulation
92.19
%
Agonist
estrogen receptor [human]:Wild
MVLN cell line
Transactivation assay
20 µg/mL
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Liu, Li; Ma, Hongyue; Tang, Yuping; Chen, Wenxing; Lu, Yin; Guo, Jianming; Duan, Jin-Ao
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 154 - 163 Title/Abstract Full Text View citing articles Show Details
IC50
275
µg
In Vitro (others)
Antimutagenic
Mutation Research - Gene...
Title/Abstract Full Text View citing articles Show Details
Kaur, Simran; Grover; Singh, Majar; Kaur, Satwinderjeet
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 1998 , vol. 419, # 1-3 p. 169 - 179 Title/Abstract Full Text View citing articles Show Details
5.25
IC50
0.95
mg/L
In Vitro (others)
Antioxidant
Phytochemistry, 2008 , ...
Title/Abstract Full Text View citing articles Show Details
Agnihotri, Vijai K.; ElSohly, Hala N.; Khan, Shabana I.; Smillie, Troy J.; Khan, Ikhlas A.; Walker, Larry A.
Phytochemistry, 2008 , vol. 69, # 10 p. 2061 - 2066 Title/Abstract Full Text View citing articles Show Details
3.23
IC50
100
mg/L
In Vitro (others)
Antioxidant
Phytochemistry, 2007 , ...
Title/Abstract Full Text View citing articles Show Details
Thuong, Phuong Thien; Kang, Ho Jeong; Na, MinKyun; Jin, WenYi; Youn, Ui Jung; Seong, Yeon Hee; Song, Kyung-Sik; Min, Byung-Sun; Bae, KiHwan
Phytochemistry, 2007 , vol. 68, # 19 p. 2432 - 2438
Title/Abstract Full Text View citing articles Show Details
2.77
IC50
1700
µM
Angiotensinconverting enzyme:Wild
In Vitro (others)
10 µM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Actis-Goretta, Lucas; Ottaviani, Javier I.; Fraga, Cesar G.
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 1 p. 229 - 234 Title/Abstract Full Text View citing articles Show Details
2.62
IC50
0.409
g/L
erythrocyte
In Vitro (others)
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Hamauzu, Yasunori; Inno, Takanori; Kume, Chihiro; Irie, Miho; Hiramatsu, Kohzy
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 3 p. 765 - 772 Title/Abstract Full Text View citing articles Show Details
1
% Stimulation
NA
Agonist
aryl hydrocarbon receptor [human]:Wild
Transactivation assay
Patent: WO2007/110241 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
JUNGBAUER, Alois; MEDJAKOVIC, Svjetlana; ZÖCHLING, Alfred
Patent: WO2007/110241 A1, 2007 ; Title/Abstract Full Text Show Details
1.68
IC50
21
mM
fatty acid synthase:Wild
Wang, Xuan; Song, Ke-Sheng; Guo, Qing-Xiang; Tian, Wei-Xi
Biochemical Pharmacology, 2003 , vol. 66, # 10 p. 2039 - 2047 Title/Abstract Full Text View citing articles Show Details
1.59
IC50
26
mM
fatty acid synthase:Wild
In Vitro (others)
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Wang, Xuan; Song, Ke-Sheng; Guo, Qing-Xiang; Tian, Wei-Xi
Biochemical Pharmacology, 2003 , vol. 66, # 10 p. 2039 - 2047 Title/Abstract Full Text View citing articles Show Details
1.73
MBC
3200 6400
mg/L
In Vitro (others)
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi; Nihei, Atsuko
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 5 p. 1072 - 1076 Title/Abstract Full Text View citing articles Show Details
2.59
IC50
2600
µM
Neuraminidase:Wild
In Vitro (others)
Planta Medica, 2007 , v...
Title/Abstract Full Text View citing articles Show Details
Li, Xiaofan; Ohtsuki, Takashi; Shindo, Sayaka; Sato, Masaaki; Koyano, Takashi; Preeprame, Srisomporn; Kowithayakorn, Thaworn; Ishibashi, Masami
Planta Medica, 2007 , vol. 73, # 11 p. 1195 - 1196 Title/Abstract Full Text View citing articles Show Details
3.78
EC50
0.165
mM
In Vitro (others)
0.0625000 mM
Toxic
Chemosphere, 2005 , vol...
Title/Abstract Full Text View citing articles Show Details
Kamaya, Yasushi; Fukaya, Yuki; Suzuki, Kyoji
Chemosphere, 2005 , vol. 59, # 2 p. 255 - 261 Title/Abstract Full Text View citing articles Show Details
3.95
EC50
0.112
mM
In Vitro (others)
0.0625000 mM
Toxic
Chemosphere, 2005 , vol...
Title/Abstract Full Text View citing articles Show Details
Kamaya, Yasushi; Fukaya, Yuki; Suzuki, Kyoji
Chemosphere, 2005 , vol. 59, # 2 p. 255 - 261 Title/Abstract Full Text View citing articles Show Details
%
91.86
%
In Vitro (others)
62.5000 µg/mL
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Bitis, Leyla; Kultur, Sukran; Melkoglu, Gulay; Ozsoy, Nurten; Can, Ayse
Natural Product Research, 2010 , vol. 24, # 6 p. 580 - 589 Title/Abstract Full Text View citing articles Show Details
3.89
EC50
22.2
µg/mL
In Vitro (others)
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Bitis, Leyla; Kultur, Sukran; Melkoglu, Gulay; Ozsoy, Nurten; Can, Ayse
Natural Product Research, 2010 , vol. 24, # 6 p. 580 - 589 Title/Abstract Full Text View citing articles Show Details
4.12
IC50
76
µM
HEK cell line
Transactivation assay
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Morais, Mauro C. C.; Luqman, Suaib; Kondratyuk, Tamara P.; Petronio, Maicon S.; Regasini, Luis O.; Silva, Dulce H. S.; Bolzani, Vanderlan S.; Soares, Christiane P.; Pezzuto, John M.
Natural Product Research, 2010 , vol. 24, # 18 p. 1758 - 1765 Title/Abstract Full Text View citing articles Show Details
IC50
>
500
µmol
Tyrosinase:Wild
Enzymology inhibition
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
IC50
14
µmol
In Vitro (others)
Antiinflammatory
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
2.17
Ki
6.7
mM
In Vitro (others)
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Pastore, Donato; Laus, Maura N.; Tozzi, Damiana; Fogliano, Vincenzo; Soccio, Mario; Flagella, Zina
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 20 p. 9682 - 9692 Title/Abstract Full Text View citing articles Show Details
4.91
IC50
2.1
µg/mL
HL-60 cell line
In Vitro (others)
0.0100000 µg/mL
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Dobroslawa, Bialonska; Kasimsetty, Sashi G.; Khan, Shabana I.; Daneel, Ferreira
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 21 p. 10181 - 10186 Title/Abstract Full Text View citing articles Show Details
4.7
MEC
20
µM
erythrocyte
In Vitro (others)
10 µM
Antihemolytic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details
3.23
MFC
0.59
µmol/mL
In Vitro (others)
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
0.295
µmol/mL
In Vitro (others)
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422
Title/Abstract Full Text View citing articles Show Details
3.87
IC50
136
µM
Proto-oncogene tyrosine-protein kinase Src [human]:Wild
thrombocyte
Enzymology inhibition
Journal of enzyme inhibi...
Title/Abstract Full Text Show Details
Enzymology inhibition
Patent: WO2004/9833 A2...
Title/Abstract Full Text Show Details
Enzymology inhibition
100 µM
Patent: WO2004/9833 A2...
Title/Abstract Full Text Show Details
In Vitro (others)
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Palacios; Cespon; Martin De La Vega; Roy; Serrano; Salinas; Gonzalez-Porque
Journal of enzyme inhibition, 2001 , vol. 16, # 6 p. 527 - 533 Title/Abstract Full Text Show Details
4.43
IC50
37.5
µM
Inositol polyphosphate multikinase [human]:Wild
MAYR, Georg W.; NALASKOWSKI, Marcus M.; HILLEMEIER, Kirsten
Patent: WO2004/9833 A2, 2004 ; Title/Abstract Full Text Show Details
4.03
% Inhibition
52
%
Inositol polyphosphate multikinase [human]:Wild
MAYR, Georg W.; NALASKOWSKI, Marcus M.; HILLEMEIER, Kirsten
Patent: WO2004/9833 A2, 2004 ; Title/Abstract Full Text Show Details
5.23
IC50
5.94
µM
Kubo, Isao; Kinst-Hori, Ikuyo; Kubo, Yumi; Yamagiwa, Yoshiro; Kamikawa, Tadao; Haraguchi, Hiroyuki
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 4 p. 1393 - 1399 Title/Abstract Full Text View citing articles Show Details
2.35
ID50
4.5
mM
Tyrosinase [mushroom]:Wild
In Vitro (others)
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Kinst-Hori, Ikuyo; Kubo, Yumi; Yamagiwa, Yoshiro; Kamikawa, Tadao; Haraguchi, Hiroyuki
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 4 p. 1393 - 1399 Title/Abstract Full Text View citing articles Show Details
4.02
IC50
16.1
mg/L
In Vitro (others)
Antiprotozoal
Planta Medica, 2006 , v...
Title/Abstract Full Text View citing articles Show Details
Cao, Shugeng; Ranarivelo, Lalasoa; Ratsimbason, Michel; Randrianasolo, Sennen; Ratovoson, Fidy; Andrianjafy, Mamisoa; Kingston, David G. I.
Planta Medica, 2006 , vol. 72, # 15 p. 1438 - 1440 Title/Abstract Full Text View citing articles Show Details
4.32
IC50
8.2
mg/L
In Vitro (others)
Antiprotozoal
Planta Medica, 2006 , v...
Title/Abstract Full Text View citing articles Show Details
Cao, Shugeng; Ranarivelo, Lalasoa; Ratsimbason, Michel; Randrianasolo, Sennen; Ratovoson, Fidy; Andrianjafy, Mamisoa; Kingston, David G. I.
Planta Medica, 2006 , vol. 72, # 15 p. 1438 - 1440 Title/Abstract Full Text View citing articles Show Details
4.12
IC50
13
mg/L
A2780 cell line
In Vitro (others)
Cytotoxic
Planta Medica, 2006 , v...
Title/Abstract Full Text View citing articles Show Details
Cao, Shugeng; Ranarivelo, Lalasoa; Ratsimbason, Michel; Randrianasolo, Sennen; Ratovoson, Fidy; Andrianjafy, Mamisoa; Kingston, David G. I.
Planta Medica, 2006 , vol. 72, # 15 p. 1438 - 1440 Title/Abstract Full Text View citing articles Show Details
3.47
% Inhibition
42.2
%
glycerol-3-phosphate dehydrogenase:Wild
3T3-L1 cell line
Enzymology inhibition
250 µM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Hsu, Chin-Lin; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 21 p. 8404 - 8410 Title/Abstract Full Text View citing articles Show Details
3.22
% Inhibition
29.2
%
3T3-L1 cell
In Vitro
250 µM
Journal of Agricultural ...
line
(others)
Title/Abstract Full Text View citing articles Show Details
Hsu, Chin-Lin; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 21 p. 8404 - 8410 Title/Abstract Full Text View citing articles Show Details
2.7
% Inhibition
<
50
%
Tyrosinase:Wild
Enzymology inhibition
2 mM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Liu, Qing; Zhang, Ying-Tun; Yang, Chong-Ren; Xu, Mei
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 2 p. 586 - 590 Title/Abstract Full Text View citing articles Show Details
3.98
IC50
105.41
µM
xanthine oxidase:Wild
In Vitro (others)
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Wu, Nan; Zu, Yuangang; Fu, Yujie; Kong, Yu; Zhao, Jintong; Li, Xiaojuan; Li, Ji; Wink, Michael; Efferth, Thomas
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 8 p. 4737 - 4743 Title/Abstract Full Text View citing articles Show Details
3.58
IC50
261
µM
Tyrosinase:Wild
Enzymology inhibition
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Gao, Da-Fang; Xu, Min; Yang, Chong-Ren; Xu, Mei; Zhang, Ying-Jun
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 15 p. 8820 - 8824 Title/Abstract Full Text View citing articles Show Details
4.3
IC50
50
µM
enzyme:Wild
In Vitro (others)
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Nakai, Masaaki; Fukui, Yuko; Asami, Sumio; Toyoda-Ono, Yoshiko; Iwashita, Takashi; Shibata, Hiroshi; Mitsunaga, Tohru; Hashimoto, Fumio; Kiso, Yoshinobu
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 11 p. 4593 - 4598 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
50
µg/mL
Enzymology inhibition
Fitoterapia, 2009 , vol...
Title/Abstract Full Text View citing articles Show Details
Kim, Hyoung Ja; Lee, Jun Young; Kim, Sung Min; Park, Da-Ae; Jin, Changbae; Hong, Seon Pyo; Lee, Yong Sup
Fitoterapia, 2009 , vol. 80, # 1 p. 73 - 76 Title/Abstract Full Text View citing articles Show Details
3.62
IC50
241
µM
P-selectin [human]:Wild
In Vitro (others)
Patent: EP1481669 A1, ...
Title/Abstract Full Text Show Details
P-selectin [human]:Wild
In Vitro (others)
Patent: EP1481669 A1, ...
Title/Abstract Full Text Show Details
P-selectin [human]:Wild
In Vitro (others)
Patent: EP1481669 A1, ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antioxidant
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
YAMANOUCHI PHARMACEUTICAL CO. LTD.
Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details
5.07
IC50
8.5
µM
YAMANOUCHI PHARMACEUTICAL CO. LTD.
Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details
5.14
IC50
7.2
µM
YAMANOUCHI PHARMACEUTICAL CO. LTD.
Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details
4.4
IC50
40
µM
Ozgova, Sarka; Hermanek, Josef; Gut, Ivan
Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details
4.4
IC50
40
µM
In Vitro (others)
Antioxidant
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Ozgova, Sarka; Hermanek, Josef; Gut, Ivan
Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details
4.4
IC50
40
µM
In Vitro (others)
Antioxidant
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Ozgova, Sarka; Hermanek, Josef; Gut, Ivan
Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details
4.1
IC50
80
µM
In Vitro (others)
Antioxidant
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Ozgova, Sarka; Hermanek, Josef; Gut, Ivan
Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details
5.17
IC50
6.7
µM
In Vitro (others)
Antioxidant
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Ozgova, Sarka; Hermanek, Josef; Gut, Ivan
Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details
3.09
IC50
818.6
µM
enzyme:Wild
In Vitro (others)
10 µM
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Zhang, Kai; Yang, Er-Bin; Tang, Wen-Ying; Wong, Kim Ping; Mack, Peter
Biochemical Pharmacology, 1997 , vol. 54, # 9 p. 1047 - 1053 Title/Abstract Full Text View citing articles Show Details
4.26
IC50
54.7
µM
integrase [Human immunodeficiency virus]:Wild
In Vitro (others)
Planta Medica, 2002 , v...
Title/Abstract Full Text View citing articles Show Details
Ahn, Mi-Jeong; Chul, Young Kim; Ji, Suk Lee; Tae, Gyun Kim; Seung, Hee Kim; Lee, Chong-Kyo; Lee, Bo-Bin; Shin, Cha-Gyun; Huh, Hoon; Kim, Jinwoong
Planta Medica, 2002 , vol. 68, # 5 p. 457 - 459 Title/Abstract Full Text View citing articles Show Details
4
IC50
100
µM
Reverse transcriptase [Human immunodeficiency virus]:Wild
In Vitro (others)
Planta Medica, 2002 , v...
Title/Abstract Full Text View citing articles Show Details
Ahn, Mi-Jeong; Chul, Young Kim; Ji, Suk Lee; Tae, Gyun Kim; Seung, Hee Kim; Lee, Chong-Kyo; Lee, Bo-Bin; Shin, Cha-Gyun; Huh, Hoon; Kim, Jinwoong
Planta Medica, 2002 , vol. 68, # 5 p. 457 - 459 Title/Abstract Full Text View citing articles Show Details
3.44
EC50
360
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
3.22
EC50
600
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
2.94
EC50
1158
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
2.41
EC50
3865
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
3.19
EC50
640
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
3.11
EC50
780
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
3.13
EC50
740
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
3.08
EC50
840
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
4.57
EC50
27
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
3.86
EC50
137
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
3.3
EC50
500
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details
3.91
EC50
123
µM
In Vitro (others)
1 µM
Germination Effect
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459
Title/Abstract Full Text View citing articles Show Details
5.23
EC50
1
mg/L
In Vitro (others)
Antiproliferative
Water Research, 2001 , ...
Title/Abstract Full Text View citing articles Show Details
Nakai, Satoshi; Inoue, Yutaka; Hosomi, Masaaki
Water Research, 2001 , vol. 35, # 7 p. 1855 - 1859 Title/Abstract Full Text View citing articles Show Details
Concentration
232
µM
In Vitro (others)
Antioxidant
Food Chemistry, 2012 , ...
Title/Abstract Full Text View citing articles Show Details
Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.
Food Chemistry, 2012 , vol. 133, # 3 p. 697 - 706 Title/Abstract Full Text View citing articles Show Details
5.48
IC50
3.3
µM
In Vitro (others)
Antioxidant
Food Chemistry, 2012 , ...
Title/Abstract Full Text View citing articles Show Details
Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.
Food Chemistry, 2012 , vol. 133, # 3 p. 697 - 706 Title/Abstract Full Text View citing articles Show Details
3.89
IC50
0.00013
M
In Vitro (others)
1.00000E08 M
Inotropic : Negative
Fitoterapia, 2010 , vol...
Title/Abstract Full Text View citing articles Show Details
Lee, Hobeom; Lee, Ji Yun; Suh, Moo Hyun; Sim, Sang-Soo; Lee, Min-Won; Kim, Chang Jong
Fitoterapia, 2010 , vol. 81, # 7 p. 820 - 825 Title/Abstract Full Text View citing articles Show Details
3.47
EC50
335
µM
Hep G2
In Vitro (others)
50 µM
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
4.18
EC50
65.4
µM
Hep G2
In Vitro (others)
10 µM
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
3.5
EC50
318
µM
Hep G2
In Vitro (others)
50 µM
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
3.57
EC50
270 350
µM
Hep G2
In Vitro (others)
50 µM
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
4.19
EC50
64.3
µM
Hep G2
In Vitro (others)
10 µM
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
4.29
EC50
51.3 -
µM
Hep G2
In Vitro
10 µM
Antioxidant
Journal of Agricultural ...
77.3
(others)
Title/Abstract Full Text View citing articles Show Details
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
5.49
IC50
3.2
µM
In Vitro (others)
0.0100000 mM
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Barreto, Jacqueline C.; Trevisan, Maria T. S.; Hull, William E.; Erben, Gerhard; De Brito, Edy S.; Pfundstein, Beate; Wuertele, Gerd; Spiegelhalder, Bertold; Owen, Robert W.
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 14 p. 5599 - 5610 Title/Abstract Full Text View citing articles Show Details
5.3
EC50
5.01
µM
In Vitro (others)
0.0100000 mM
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Barreto, Jacqueline C.; Trevisan, Maria T. S.; Hull, William E.; Erben, Gerhard; De Brito, Edy S.; Pfundstein, Beate; Wuertele, Gerd; Spiegelhalder, Bertold; Owen, Robert W.
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 14 p. 5599 - 5610 Title/Abstract Full Text View citing articles Show Details
3.09
IC50
821
µM
Tyrosinase:Wild
Enzymology inhibition
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Gao, Da-Fang; Zhang, Ying-Jun; Yang, Chong-Ren; Chen, Ke-Ke; Jiang, Hong-Jian
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 16 p. 7517 - 7521 Title/Abstract Full Text View citing articles Show Details
% Inhibition
97.7
%
In Vitro (others)
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Huang, Din-Wen; Kuo, Yueh-Hsiung; Lin, Fang-Yi; Lin, Yun-Lian; Chiang, Wenchang
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 6 p. 2259 - 2266 Title/Abstract Full Text View citing articles Show Details
5.95
EC50
0.19
µg/mL
In Vitro (others)
Antioxidant
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Huang, Din-Wen; Kuo, Yueh-Hsiung; Lin, Fang-Yi; Lin, Yun-Lian; Chiang, Wenchang
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 6 p. 2259 - 2266 Title/Abstract Full Text View citing articles Show Details
4.38
EC50
7.1
µg/mL
RAW 264.7 cell line
In Vitro (others)
Antiinflammatory
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Huang, Din-Wen; Kuo, Yueh-Hsiung; Lin, Fang-Yi; Lin, Yun-Lian; Chiang, Wenchang
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 6 p. 2259 - 2266 Title/Abstract Full Text View citing articles Show Details
4.44
IC50
6.1
mg/L
In Vitro (others)
0 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details
4.5
IC50
5.4
mg/L
In Vitro (others)
0 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details
4.11
IC50
13.2
mg/L
In Vitro (others)
0 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details
4.55
IC50
4.8
mg/L
In Vitro (others)
0 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details
4.44
IC50
6.2
mg/L
In Vitro (others)
0 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details
4.41
IC50
6.6
mg/L
PLC/PRF/5 cell line
In Vitro (others)
0 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details
3.44
MIC
62.5
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro
Antibiotic
Patent: EP1604660 A1, ...
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
(others)
Title/Abstract Full Text Show Details
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µg/mL
In Vitro (others)
Antibiotic
Patent: EP1604660 A1, ...
Title/Abstract Full Text Show Details
µM
xanthine oxidase:Wild
In Vitro (others)
50 µM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.74
MIC
31.3
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.44
MIC
62.5
Alps Pharmaceutical Ind. Co. Ltd.
Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details
3.7
IC50
200
Lin, Jen-Kun; Chen, Ping-Chung; Ho, Chi-Tang; Lin-Shiau, Shoei-Yn
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 7 p. 2736 - 2743 Title/Abstract Full Text View citing articles Show Details
EC50
3.8
µg
In Vitro (others)
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Pandurangan; Bose, Chinchu; Banerji
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5328 - 5330 Title/Abstract Full Text View citing articles Show Details
2.15
IC50
7.1
mM
20S Proteasome [human]:Wild
JURKAT
Enzymology inhibition
Patent: US2002/151582 ...
Title/Abstract Full Text Show Details
Prolyl endopeptidase:Wild
Enzymology inhibition
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Dou, Q. Ping; Nam, Sangkil; Smith, David M.
Patent: US2002/151582 A1, 2002 ; Title/Abstract Full Text Show Details
1
IC50
>
400
µM
Lee, Seung-Ho; Jun, Mira; Choi, Ji-Young; Yang, Eun-Ju; Hur, Jong-Moon; Bae, Kihwan; Seong, Yeon-Hee; Huh, Tae-Lin; Song, Kyung-Sik
Archives of Pharmacal Research, 2007 , vol. 30, # 7 p. 827 - 833 Title/Abstract Full Text View citing articles Show Details
5
% Inhibition
@
Esterase [rabbit]:Wild
liver
Enzymology inhibition
10 µM
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Chieli, Elisabetta; Romiti, Nadia; Rodeiro, Idania; Garrido, Gabino
Food and Chemical Toxicology, 2009 , vol. 47, # 11 p. 2703 - 2710 Title/Abstract Full Text View citing articles Show Details
3.69
IC50
206
µM
Chitin synthase 2:Wild
In Vitro (others)
Planta Medica, 2001 , v...
Title/Abstract Full Text View citing articles Show Details
Hwang; Ahn; Lee; Kim; Bok
Planta Medica, 2001 , vol. 67, # 6 p. 501 - 504 Title/Abstract Full Text View citing articles Show Details
1.73
MBC
3200
mg/L
In Vitro (others)
Antimicrobial
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Xiao, Ping; Fujita, Ken'ichi
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 113 - 116 Title/Abstract Full Text View citing articles Show Details
2.42
IC50
644
µg/mL
Tyrosinase [mushroom]:Wild
In Vitro (others)
Molecules (Basel, Switze...
Title/Abstract Full Text Show Details
In Vitro (others)
1000 µM
Antiproliferative
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Nithitanakool, Saruth; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart
Molecules (Basel, Switzerland), 2009 , vol. 14, # 1 p. 257 - 265 Title/Abstract Full Text Show Details
4.36
IC50
43.3
µM
Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1000
µM
Hyaluronidase [taurine cattle]:Wild
Enzymology inhibition
Bioscience, Biotechnolog...
Title/Abstract Full Text View citing articles Show Details
Barla, Florin; Higashijima, Hayato; Funai, Shingo; Sugimoto, Keiichiro; Harada, Naoki; Yamaji, Ryoichi; Fujita, Tomoyuki; Nakano, Yoshihisa; Inui, Hiroshi
Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 10 p. 2335 - 2337 Title/Abstract Full Text View citing articles Show Details
2.68
IC50
2.07
mM
Matrix metalloproteinase-
Enzymology inhibition
Bioscience, Biotechnolog...
Title/Abstract Full Text View citing articles Show Details
9:Wild
Barla, Florin; Higashijima, Hayato; Funai, Shingo; Sugimoto, Keiichiro; Harada, Naoki; Yamaji, Ryoichi; Fujita, Tomoyuki; Nakano, Yoshihisa; Inui, Hiroshi
Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 10 p. 2335 - 2337 Title/Abstract Full Text View citing articles Show Details
4.73
EC50
18.5
µM
In Vitro (others)
Antioxidant
Bioscience, Biotechnolog...
Title/Abstract Full Text View citing articles Show Details
Barla, Florin; Higashijima, Hayato; Funai, Shingo; Sugimoto, Keiichiro; Harada, Naoki; Yamaji, Ryoichi; Fujita, Tomoyuki; Nakano, Yoshihisa; Inui, Hiroshi
Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 10 p. 2335 - 2337 Title/Abstract Full Text View citing articles Show Details
5.17
IC50
6.7
µM
In Vitro (others)
Antioxidant
Anti-Cancer Drugs, 2011 ...
Title/Abstract Full Text View citing articles Show Details
Soucek, Pavel; Kondrova, Eliska; Hermanek, Josef; Stopka, Pavel; Boumendjel, Ahcene; Ueng, Yune-Fang; Gut, Ivan
Anti-Cancer Drugs, 2011 , vol. 22, # 2 p. 176 - 184 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
40
µM
In Vitro (others)
Antioxidant
Anti-Cancer Drugs, 2011 ...
Title/Abstract Full Text View citing articles Show Details
Soucek, Pavel; Kondrova, Eliska; Hermanek, Josef; Stopka, Pavel; Boumendjel, Ahcene; Ueng, Yune-Fang; Gut, Ivan
Anti-Cancer Drugs, 2011 , vol. 22, # 2 p. 176 - 184 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
200
µg/mL
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.03
MIC
1600
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.33
MIC
800
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.63
MIC
400
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.33
MIC
800
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.63
MIC
400
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.63
MIC
400
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.63
MIC
400
µg/mL
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antibiotic
Patent: WO2006/126675 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antiproliferative
Patent: WO2012/21981 A...
Title/Abstract Full Text Show Details
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.63
MIC
400
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.63
MIC
400
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.63
MIC
400
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.93
MIC
200
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.03
MIC
1600
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
2.33
MIC
800
µg/mL
KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto
Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details
4.05
IC50
89.3
µM
Caco-2
FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC; UNIVERSITY OF RHODE ISLAND; SEERAM, Navindra, P.; LI, Liya; BELAND, Genevieve; BARBEAU, Julie
Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details
pX
Parameter
4.19
IC50
Value (qual)
Value (quant)
Unit
64.9
µM
Action on Target
Target
Tissue/Organ
Cell
Bioassay
HCT 116 cell line
In Vitro (others)
Dose
Effect
Reference (expand all/collapse all)
Antiproliferative
Patent: WO2012/21981 A...
Title/Abstract Full Text Show Details
FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC; UNIVERSITY OF RHODE ISLAND; SEERAM, Navindra, P.; LI, Liya; BELAND, Genevieve; BARBEAU, Julie
Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details
4.05
IC50
89.3
µM
Caco-2
In Vitro (others)
Antiproliferative
Patent: WO2012/21981 A...
Title/Abstract Full Text Show Details
SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie
Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details
4.19
IC50
64.9
µM
HCT 116 cell line
In Vitro (others)
Antiproliferative
Patent: WO2012/21981 A...
Title/Abstract Full Text Show Details
Caco-2
In Vitro (others)
Antiproliferative
Patent: WO2012/21981 A...
Title/Abstract Full Text Show Details
In Vitro (others)
3200 mg/L
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie
Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details
4.05
IC50
89.3
µM
SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie
Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details
2.03
MBC
1600
mg/L
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 23 p. 6692 - 6696 Title/Abstract Full Text View citing articles Show Details
4.5
IC50
31.7
µM
In Vitro (others)
50 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details
5.28
IC50
5.2
µM
enzyme:Wild
In Vitro (others)
Phytochemistry, 2007 , ...
Title/Abstract Full Text View citing articles Show Details
Wansi, Jean Duplex; Lallemand, Marie-Christine; Chiozem, David Daco; Toze, Flavien Aristide A.; Mbaze, Luc Meva'a; Naharkhan, Shamsun; Iqbal, Muhammad Choudhary; Tillequin, Francois; Wandji, Jean; Fomum, Zacharias Tanee
Phytochemistry, 2007 , vol. 68, # 15 p. 2096 - 2100 Title/Abstract Full Text View citing articles Show Details
3.71
IC50
194.4
µM
enzyme:Wild
In Vitro (others)
Phytochemistry, 2007 , ...
Title/Abstract Full Text View citing articles Show Details
Wansi, Jean Duplex; Lallemand, Marie-Christine; Chiozem, David Daco; Toze, Flavien Aristide A.; Mbaze, Luc Meva'a; Naharkhan, Shamsun; Iqbal, Muhammad Choudhary; Tillequin, Francois; Wandji, Jean; Fomum, Zacharias Tanee
Phytochemistry, 2007 , vol. 68, # 15 p. 2096 - 2100 Title/Abstract Full Text View citing articles Show Details
4.81
IC50
15.6
µM
enzyme:Wild
In Vitro (others)
Phytochemistry, 2007 , ...
Title/Abstract Full Text View citing articles Show Details
Wansi, Jean Duplex; Lallemand, Marie-Christine; Chiozem, David Daco; Toze, Flavien Aristide A.; Mbaze, Luc Meva'a; Naharkhan, Shamsun; Iqbal, Muhammad Choudhary; Tillequin, Francois; Wandji, Jean; Fomum, Zacharias Tanee
Phytochemistry, 2007 , vol. 68, # 15 p. 2096 - 2100 Title/Abstract Full Text View citing articles Show Details
4.28
IC50
52.5
µM
In Vitro (others)
Antioxidant
Arzneimittel-Forschung/D...
Title/Abstract Full Text View citing articles Show Details
Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira
Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details
3.39
EC50
404.3
µM
VERO
In Vitro (others)
Anti-Herpes
Arzneimittel-Forschung/D...
Title/Abstract Full Text View citing articles Show Details
Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira
Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details
3.1
EC50
789.91
µM
VERO
In Vitro (others)
Anti-Herpes
Arzneimittel-Forschung/D...
Title/Abstract Full Text View citing articles Show Details
Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira
Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details
2.98
CC50
1048.14
µM
VERO
In Vitro (others)
3.91000 mg/L
Cytotoxic
Arzneimittel-Forschung/D...
Title/Abstract Full Text View citing articles Show Details
Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira
Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details
2.57
IC50
458.9
mg/L
enzyme:Wild
In Vitro (others)
Carbohydrate Research, 2...
Title/Abstract Full Text View citing articles Show Details
Shinde, Jayantrao; Taldone, Tony; Barletta, Michael; Kunaparaju, Naveen; Hu, Bo; Kumar, Sunil; Placido, Jessica; Zito, S. William
Carbohydrate Research, 2008 , vol. 343, # 7 p. 1278 - 1281 Title/Abstract Full Text View citing articles Show Details
3.5
LC50
54.3
ppm
In Vitro (others)
Toxic
Fitoterapia, 2004 , vol...
Title/Abstract Full Text View citing articles Show Details
Urrea-Bulla; Suarez M; Moreno-Murillo
Fitoterapia, 2004 , vol. 75, # 3-4 p. 392 - 394 Title/Abstract Full Text View citing articles Show Details
3.3
IC50
500
µM
enzyme:Wild
In Vitro (others)
Planta Medica, 2004 , v...
Title/Abstract Full Text View citing articles Show Details
Kiss, Anna; Kowalski, Jozef; Melzig, Matthias F.
Planta Medica, 2004 , vol. 70, # 10 p. 919 - 923 Title/Abstract Full Text View citing articles Show Details
3.32
IC50
480
µM
enzyme:Wild
In Vitro (others)
Planta Medica, 2004 , v...
Title/Abstract Full Text View citing articles Show Details
Kiss, Anna; Kowalski, Jozef; Melzig, Matthias F.
Planta Medica, 2004 , vol. 70, # 10 p. 919 - 923 Title/Abstract Full Text View citing articles Show Details
5
% Inhibition
26.6 47.7
%
Hep G2
In Vitro (others)
1 µg/mL
Antiviral
Asian Journal of Chemist...
Title/Abstract Full Text View citing articles Show Details
Xiang, Zhao Bao; Mo, Hai Qing; Qu, Zhong Tang; Xu, Hong Mei; Jiang, Hum Zhong
Asian Journal of Chemistry, 2011 , vol. 23, # 8 p. 3759 - 3760 Title/Abstract Full Text View citing articles Show Details
5.13
% Inhibition
20.3 68.5
%
Hep G2
In Vitro (others)
1 µg/mL
Antiviral
Asian Journal of Chemist...
Title/Abstract Full Text View citing articles Show Details
Xiang, Zhao Bao; Mo, Hai Qing; Qu, Zhong Tang; Xu, Hong Mei; Jiang, Hum Zhong
Asian Journal of Chemistry, 2011 , vol. 23, # 8 p. 3759 - 3760 Title/Abstract Full Text View citing articles Show Details
4.65
IC50
22.2
µM
G-protein coupled receptor 35:Wild
HT-29
In Vitro (others)
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Deng, Huayun; Fang, Ye
Naunyn-Schmiedeberg's Archives of Pharmacology, 2012 , vol. 385, # 7 p. 729 - 737 Title/Abstract Full Text View citing articles Show Details
5.94
EC50
1.16
µM
G-protein coupled receptor 35:Wild
HT-29
In Vitro (others)
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Deng, Huayun; Fang, Ye
Naunyn-Schmiedeberg's Archives of Pharmacology, 2012 , vol. 385, # 7 p. 729 - 737 Title/Abstract Full Text View citing articles Show Details
4.94
EC50
11.4
µM
G-protein coupled receptor 35:Wild
In Vitro (others)
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Deng, Huayun; Fang, Ye
Naunyn-Schmiedeberg's Archives of Pharmacology, 2012 , vol. 385, # 7 p. 729 - 737 Title/Abstract Full Text View citing articles Show Details
3.55
IC50
279.6
µM
platelet-rich plasma cell
In Vitro (others)
Pharmazie, 2010 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook
Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
=
-43
%
Inhibitor
Hematin [Plasmodium falciparum]:Wild
100 µg/mL
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Kurosawa; Dorn; Kitsuji-Shirane; Shimada; Satoh; Matile; Hofheinz; Masciadri; Kansy; Ridley
Antimicrobial Agents and Chemotherapy, 2000 , vol. 44, # 10 p. 2638 - 2644 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
300
µM
Anthrax toxin receptor 2:Mutated
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Cryan, Lorna M.; Bazinet, Lauren; Habeshian, Kaiane A.; Cao, Shugeng; Clardy, Jon; Christensen, Kenneth A.; Rogers, Michael S.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 1940 - 1945 Title/Abstract Full Text View citing articles Show Details
5
IC50
=
9.9
µM
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Teixeira, Jose; Silva, Tiago; Benfeito, Sofia; Gaspar, Alexandra; Garrido, E. Manuela; Garrido, Jorge; Borges, Fernanda
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 289 - 296 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
45.9
%
Nitric oxide synthase, inducible:Wild
RAW 264.7 cell line
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas
Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details
3.2
IC50
=
631.6
µM
Nitric oxide synthase, inducible:Wild
RAW 264.7 cell line
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas
Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details
5.11
IC50
=
7.8
µM
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Teixeira, Jose; Silva, Tiago; Benfeito, Sofia; Gaspar, Alexandra; Garrido, E. Manuela; Garrido, Jorge; Borges, Fernanda
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 289 - 296 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
32.4
%
Nitric oxide synthase, inducible:Wild
RAW 264.7 cell line
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas
Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
10.7
%
Nitric oxide synthase, inducible:Wild
RAW 264.7 cell line
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas
Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
31.7
%
Tyrosinase [mushroom]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Vontzalidou, Argyro; Zoidis, Grigoris; Chaita, Eliza; Makropoulou, Maria; Aligiannis, Nektarios; Lambrinidis, George; Mikros, Emmanuel; Skaltsounis, Alexios-Leandros
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 17 p. 5523 - 5526 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
24.7
%
Nitric oxide synthase, inducible:Wild
RAW 264.7 cell line
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas
Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details
4.3
IC50
=
50
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Ni, Nanting; Choudhary, Gaurav; Li, Minyong; Wang, Binghe
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 5 p. 1567 - 1572 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
22.5
%
BGC-823 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Chen, Zhuo; Liu, Yu-Mei; Yang, Song; Song, Bao-An; Xu, Guang-Fang; Bhadury, Pinaki S.; Jin, Lin-Hong; Hu, De-Yu; Liu, Fang; Xue, Wei; Zhou, Xia
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1337 - 1344 Title/Abstract Full Text View citing articles Show Details
5.2
IC50
=
0.00636
mM
Inhibitor
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Lopes, Thiago Inacio Barros; Coelho, Roberta Gomes; Yoshida, Nidia Cristiane; Honda, Neli Kika
Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 11 p. 1551 - 1554 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
6.7
%
BGC-823 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Chen, Zhuo; Liu, Yu-Mei; Yang, Song; Song, Bao-An; Xu, Guang-Fang; Bhadury, Pinaki S.; Jin, Lin-Hong; Hu, De-Yu; Liu, Fang; Xue, Wei; Zhou, Xia
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1337 - 1344 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
16.7
%
BGC-823 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Chen, Zhuo; Liu, Yu-Mei; Yang, Song; Song, Bao-An; Xu, Guang-Fang; Bhadury, Pinaki S.; Jin, Lin-Hong; Hu, De-Yu; Liu, Fang; Xue, Wei; Zhou, Xia
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1337 - 1344 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
10.2
%
BGC-823 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Chen, Zhuo; Liu, Yu-Mei; Yang, Song; Song, Bao-An; Xu, Guang-Fang; Bhadury, Pinaki S.; Jin, Lin-Hong; Hu, De-Yu; Liu, Fang; Xue, Wei; Zhou, Xia
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1337 - 1344 Title/Abstract Full Text View citing articles Show Details
4.93
IC50
=
2
µg/mL
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila
Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details
2.89
IC50
=
220
µg/mL
Inhibitor
K-562 cell line
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila
Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details
%
=
85.6
%
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Tsao, Chuan-Chung; Shen, Yuh-Chiang; Su, Chung-Ren; Li, Chia-Ying; Liou, Meei-Jen; Dung, Nguyen-Xuan; Wu, Tian-Shung
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9867 - 9870 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
21.5
%
Inhibitor
NADPH oxidase [Mus musculus]:Wild
BV-2 cell line
= 50 µm
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Tsao, Chuan-Chung; Shen, Yuh-Chiang; Su, Chung-Ren; Li, Chia-Ying; Liou, Meei-Jen; Dung, Nguyen-Xuan; Wu, Tian-Shung
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9867 - 9870 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
50
µM
Inhibitor
Nitric oxide synthase, inducible [Mus musculus]:Wild
BV-2 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Tsao, Chuan-Chung; Shen, Yuh-Chiang; Su, Chung-Ren; Li, Chia-Ying; Liou, Meei-Jen; Dung, Nguyen-Xuan; Wu, Tian-Shung
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9867 - 9870 Title/Abstract Full Text View citing articles Show Details
3.8
IC50
=
26.9
µg/mL
Inhibitor
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Chethan; Dharmesh, Shylaja M.; Malleshi, Nagappa G.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 23 p. 10085 - 10090 Title/Abstract Full Text View citing articles Show Details
3.24
IC50
=
97.3
µg/mL
Inhibitor
Aldose reductase [human]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Chethan; Dharmesh, Shylaja M.; Malleshi, Nagappa G.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 23 p. 10085 - 10090 Title/Abstract Full Text View citing articles Show Details
2.89
IC50
=
220
µg/mL
K-562 cell line
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila
Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details
%
=
0.75
%
K-562 cell line
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila
Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
72
%
K-562 cell line
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila
Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details
2.09
IC50
=
8115
µM
Inhibitor
Plasminogen activator inhibitor 1 [human]:Wild
Patent: WO2008/131047 ...
Title/Abstract Full Text Show Details
Plasminogen activator inhibitor 1 [human]:Wild
Patent: WO2008/131047 ...
Title/Abstract Full Text Show Details
Journal of Natural Produ...
Title/Abstract Full Text Show Details
Journal of natural produ...
Title/Abstract Full Text Show Details
Journal of natural produ...
Title/Abstract Full Text Show Details
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Patent: WO2008/131047 A2, 2008 ; Title/Abstract Full Text Show Details
3.65
IC50
=
225.2
µM
Inhibitor
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Patent: WO2008/131047 A2, 2008 ; Title/Abstract Full Text Show Details
1
ED50
NA
Liu; Pezzuto; Kinghorn
Journal of Natural Products (Lloydia), 1988 , vol. 51, # 3 p. 619 - 620 Title/Abstract Full Text Show Details
4.48
IC50
=
33
µM
KAZUKI SAITO; MAKOTO MATSUMOTO; TOSHIKAZU SEKINE; ISAMU MURAKOSHI; NAOKO MORISAKI; SHIGEO IWASAKI
Journal of natural products, 1989 , vol. 52, # 6 p. 1221 - 1221 Title/Abstract Full Text Show Details
4.72
IC50
=
19
µM
Inhibitor
KAZUKI SAITO; MAKOTO MATSUMOTO; TOSHIKAZU SEKINE; ISAMU MURAKOSHI; NAOKO MORISAKI; SHIGEO IWASAKI
Journal of natural products, 1989 , vol. 52, # 6 p. 1221 - 1221 Title/Abstract Full Text Show Details
5.39
ED50
=
0.7
µg/mL
P388 cell line
Journal of Natural Produ...
Title/Abstract Full Text Show Details
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Liu; Pezzuto; Kinghorn
Journal of Natural Products (Lloydia), 1988 , vol. 51, # 3 p. 619 - 620 Title/Abstract Full Text Show Details
% Inhibition
=
23.4
%
Sugimoto, Sachiko; Chi, Guihua; Kato, Yasuyo; Nakamura, Seikou; Matsuda, Hisashi; Yoshikawa, Masayuki
Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 3 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details
%
=
71.2
%
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Kaur, Gurpreet; Athar, Mohammad; Alam, M. Sarwar
Chemico-Biological Interactions, 2008 , vol. 171, # 3 p. 272 - 282 Title/Abstract Full Text View citing articles Show Details
%
=
76.2
%
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Kaur, Gurpreet; Athar, Mohammad; Alam, M. Sarwar
Chemico-Biological Interactions, 2008 , vol. 171, # 3 p. 272 - 282
Title/Abstract Full Text View citing articles Show Details
%
=
85.7
%
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Kaur, Gurpreet; Athar, Mohammad; Alam, M. Sarwar
Chemico-Biological Interactions, 2008 , vol. 171, # 3 p. 272 - 282 Title/Abstract Full Text View citing articles Show Details
%
=
63
%
Chemico-Biological Inter...
Title/Abstract Full Text View citing articles Show Details
Kaur, Gurpreet; Athar, Mohammad; Alam, M. Sarwar
Chemico-Biological Interactions, 2008 , vol. 171, # 3 p. 272 - 282 Title/Abstract Full Text View citing articles Show Details
Activity
=
33.9
µM
Antioxidant
Patent: WO2012/35406 A...
Title/Abstract Full Text Show Details
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; UNIVERSITY OF CALCUTTA; BANDYOPADHYAY, Uday; PAL, Chinmay; BINDU, Samik; ADHIKARI, Susanta, Sekhar
Patent: WO2012/35406 A1, 2012 ; Title/Abstract Full Text Show Details
% Inhibition
=
62.87
%
Antioxidant
Letters in Drug Design a...
Title/Abstract Full Text View citing articles Show Details
Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
44
%
Antioxidant
Letters in Drug Design a...
Title/Abstract Full Text View citing articles Show Details
Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details
Activity
=
46.59
µM
Antioxidant
Patent: WO2012/35406 A...
Title/Abstract Full Text Show Details
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; UNIVERSITY OF CALCUTTA; BANDYOPADHYAY, Uday; PAL, Chinmay; BINDU, Samik; ADHIKARI, Susanta, Sekhar
Patent: WO2012/35406 A1, 2012 ; Title/Abstract Full Text Show Details
% Inhibition
=
33.72
%
Antioxidant
Letters in Drug Design a...
Title/Abstract Full Text View citing articles Show Details
Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
50.3
%
Antioxidant
Letters in Drug Design a...
Title/Abstract Full Text View citing articles Show Details
Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details
5.08
IC50
=
1.4
µg/mL
radical scavenging
Journal of Enzyme Inhibi...
Title/Abstract Full Text View citing articles Show Details
Sasidharan, Indu; Sundaresan; Nisha; Kirishna, Mahesh S.; Raghu; Jayamurthy
Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 4 p. 578 - 586 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
58.1
%
Antioxidant
Letters in Drug Design a...
Title/Abstract Full Text View citing articles Show Details
Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
47.23
%
Antioxidant
Letters in Drug Design a...
Title/Abstract Full Text View citing articles Show Details
Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details
4.5
IC50
=
31.56
µM
Antioxidant
Letters in Drug Design a...
Title/Abstract Full Text View citing articles Show Details
Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details
5.92
IC50
=
1.2
µM
radical scavenging
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Odo, Junichi; Kimura, Ayumi; Matsu-Ura, Atsushi; Ohnishi, Yuki; Saeki, Yoshiro; Yoshida, Akiko; Hayashi, Ken-Ichiro; Inoguchi, Masahiko; Ueki, Takahiko
Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 12 p. 1576 - 1581 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
5000
µM
Glycoprotein 41 [Human immunodeficiency virus 1]:Wild
ChemMedChem, 2011 , vol...
Title/Abstract Full Text View citing articles Show Details
Liu, Yan; Ke, Zhuofeng; Wu, Kwok Yiu; Liu, Shuwen; Chen, Wen-Hua; Jiang, Shibo; Jiang, Zhi-Hong
ChemMedChem, 2011 , vol. 6, # 9 p. 1654 - 1664 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1000
µM
lipase [pig]:Wild
pancreas cell
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kato, Eisuke; Yama, Michitsugu; Nakagomi, Ryo; Shibata, Toshiro; Hosokawa, Keizo; Kawabata, Jun
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 20 p. 6410 - 6412 Title/Abstract Full Text View citing articles Show Details
IC50
ND
alpha-glucosidase [Saccharomyces cerevisiae]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Wan, Chunpeng; Yuan, Tao; Li, Liya; Kandhi, Vamsikrishna; Cech, Nadja B.; Xie, Mingyong; Seeram, Navindra P.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 597 - 600 Title/Abstract Full Text View citing articles Show Details
4.69
IC50
=
20.39
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Wan, Chunpeng; Yuan, Tao; Li, Liya; Kandhi, Vamsikrishna; Cech, Nadja B.; Xie, Mingyong; Seeram, Navindra P.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 597 - 600 Title/Abstract Full Text View citing articles Show Details
4.53
IC50
=
5
µg/mL
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Gamez; Luyengi; Sang Kook Lee; Zhu; Zhou; Fong; Pezzuto; Kinghorn
Journal of Natural Products, 1998 , vol. 61, # 5 p. 706 - 708 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
µg/mL
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Cai, Lining; Wu, Christine D.
Journal of Natural Products, 1996 , vol. 59, # 10 p. 987 - 990
Title/Abstract Full Text View citing articles Show Details
5.38
EC50
=
4.2
µM
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Yasuda; Inaba; Ohmori; Endo; Kubo; Ohsawa
Journal of Natural Products, 2000 , vol. 63, # 10 p. 1444 - 1446 Title/Abstract Full Text View citing articles Show Details
%
=
86.8
%
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji
Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details
%
=
34.9
%
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji
Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details
3.04
MIC
=
156
µg/mL
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Cai, Lining; Wu, Christine D.
Journal of Natural Products, 1996 , vol. 59, # 10 p. 987 - 990 Title/Abstract Full Text View citing articles Show Details
4.66
IC50
=
21.8
µM
Inhibitor
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Park, Eun Jung; Kim, Youngleem; Kim, Jinwoong
Journal of Natural Products, 2000 , vol. 63, # 1 p. 34 - 36 Title/Abstract Full Text View citing articles Show Details
4.66
IC50
=
3.7
µg/mL
Inhibitor
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Park, Eun Jung; Kim, Youngleem; Kim, Jinwoong
Journal of Natural Products, 2000 , vol. 63, # 1 p. 34 - 36 Title/Abstract Full Text View citing articles Show Details
3.34
MIC
=
78
µg/mL
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Cai, Lining; Wu, Christine D.
Journal of Natural Products, 1996 , vol. 59, # 10 p. 987 - 990 Title/Abstract Full Text View citing articles Show Details
4.73
IC50
=
18.8
µM
HL-60 cell line
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Park, Eun Jung; Kim, Youngleem; Kim, Jinwoong
Journal of Natural Products, 2000 , vol. 63, # 1 p. 34 - 36 Title/Abstract Full Text View citing articles Show Details
4.73
IC50
=
3.2
µg/mL
HL-60 cell line
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Park, Eun Jung; Kim, Youngleem; Kim, Jinwoong
Journal of Natural Products, 2000 , vol. 63, # 1 p. 34 - 36 Title/Abstract Full Text View citing articles Show Details
%
=
61.6
%
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji
Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details
%
=
94.8
%
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji
Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details
%
=
95.7
%
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji
Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details
%
=
19
%
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji
Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details
4.23
IC50
10
µg/mL
Inhibitor
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Westenburg; Lee; Fong; Van Breemen; Pezzuto; Kinghorn
Journal of Natural Products, 2000 , vol. 63, # 12 p. 1696 - 1698 Title/Abstract Full Text View citing articles Show Details
3.34
MIC
=
78
µg/mL
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Cai, Lining; Wu, Christine D.
Journal of Natural Products, 1996 , vol. 59, # 10 p. 987 - 990 Title/Abstract Full Text View citing articles Show Details
4.06
IC50
=
14.8
µg/mL
Inhibitor
erythrocyte
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Subeki; Matsuura, Hideyuki; Takahashi, Kosaku; Yamasaki, Masahiro; Yamato, Osamu; Maede, Yoshimitsu; Katakura, Ken; Kobayashi, Sumiko; Trimurningsih; Chairul; Yoshihara, Teruhiko
Journal of Natural Products, 2005 , vol. 68, # 4 p. 537 - 539 Title/Abstract Full Text View citing articles Show Details
Activity
=
8.08
µM
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Wada, Shun-Ichi; Yasui, Yumiko; Hitomi, Teppei; Tanaka, Reiko
Journal of Natural Products, 2007 , vol. 70, # 10 p. 1605 - 1610 Title/Abstract Full Text View citing articles Show Details
6.28
IC50
0.53
µM
Inhibitor
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Wada, Shun-Ichi; Yasui, Yumiko; Hitomi, Teppei; Tanaka, Reiko
Journal of Natural Products, 2007 , vol. 70, # 10 p. 1605 - 1610 Title/Abstract Full Text View citing articles Show Details
4.1
IC50
=
13.4
µg/mL
Inhibitor
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Subeki; Matsuura, Hideyuki; Takahashi, Kosaku; Yamasaki, Masahiro; Yamato, Osamu; Maede, Yoshimitsu; Katakura, Ken; Kobayashi, Sumiko; Trimurningsih; Chairul; Yoshihara, Teruhiko
Journal of Natural Products, 2005 , vol. 68, # 4 p. 537 - 539 Title/Abstract Full Text View citing articles Show Details
4.52
IC50
=
29.9
µM
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Nuntanakorn, Paiboon; Jiang, Bei; Einbond, Linda S.; Yang, Hui; Kronenberg, Fredi; Weinstein, I. Bernard; Kennelly, Edward J.
Journal of Natural Products, 2006 , vol. 69, # 3 p. 314 - 318 Title/Abstract Full Text View citing articles Show Details
4.52
IC50
=
30
µM
Inhibitor
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Reynertson, Kurt A.; Wallace, Alison M.; Adachi, Seiji; Gil, Roberte R.; Yang, Hui; Basile, Margaret J.; D'Armiento, Jeanine; Weinstein, I. Bernard; Kennelly, Edward J.
Journal of Natural Products, 2006 , vol. 69, # 8 p. 1228 - 1230 Title/Abstract Full Text View citing articles Show Details
5.57
IC50
2.7
µM
Inhibitor
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Su, Bao-Ning; Pawlus, Alison D.; Jung, Hyun-Ah; Keller, William J.; McLaughlin, Jerry L.; Kinghorn, A. Douglas
Journal of Natural Products, 2005 , vol. 68, # 4 p. 592 - 595 Title/Abstract Full Text View citing articles Show Details
4.72
GI50
=
19
µM
mK1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kinjo, Junei; Nagao, Tsuneatsu; Tanaka, Takashi; Nonaka, Gen-Ichiro; Okabe, Hikaru
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 12 p. 1443 - 1445 Title/Abstract Full Text View citing articles Show Details
2.5
MIC
=
533
µg/mL
Inhibitor
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
5.03
IC50
=
1.6
µg/mL
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter
Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details
4.84
GI50
=
14.4
µM
Inhibitor
Biological and pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo
Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details
2.71
MIC
=
333
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
3.11
MIC
=
133
µg/mL
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
3.53
MIC
=
50
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
30
µg/mL
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter
Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details
2.5
MIC
=
533
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.56
MIC
=
467
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.71
MIC
=
333
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
=
500
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
Activity
=
1.98
mM
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rastija, Vesna; Medic-Saric, Marica
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 1 p. 400 - 408 Title/Abstract Full Text View citing articles Show Details
2.8
MIC
=
267
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
4.46
IC50
~
35
µM
Inhibitor
PLC/PRF/5 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Isuzugawa; Ogihara; Inoue
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details
4.66
GI50
=
22
µM
HeLa cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kinjo, Junei; Nagao, Tsuneatsu; Tanaka, Takashi; Nonaka, Gen-Ichiro; Okabe, Hikaru
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 12 p. 1443 - 1445 Title/Abstract Full Text View citing articles Show Details
2.45
MIC
=
600
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
3.4
MIC
=
67
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.8
MIC
=
267
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.5
MIC
=
533
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
Activity
=
4.1
µM
Biological and pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Yoshikawa, Masayuki; Ninomiya, Kiyofumi; Shimoda, Hiroshi; Nishida, Norihisa; Matsuda, Hisashi
Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 72 - 76 Title/Abstract Full Text View citing articles Show Details
2.41
MIC
=
667
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
4.07
IC50
=
14.4
µg/mL
Inhibitor
L6
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter
Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details
2.5
MIC
=
533
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.2
MIC
=
1067
µg/mL
Inhibitor
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235
Title/Abstract Full Text View citing articles Show Details
4.68
TGI
=
20.8
µM
Biological and pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo
Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details
4.46
IC50
~
35
µM
Inhibitor
HeLa cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Isuzugawa; Ogihara; Inoue
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details
5.15
GI50
=
7.1
µM
B16-F10 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kinjo, Junei; Nagao, Tsuneatsu; Tanaka, Takashi; Nonaka, Gen-Ichiro; Okabe, Hikaru
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 12 p. 1443 - 1445 Title/Abstract Full Text View citing articles Show Details
3.4
IC50
=
67
µg/mL
L6
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter
Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details
2.45
MIC
=
600
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
4.07
IC50
=
84.5
µM
Inhibitor
catechol Omethyltransferase [Rattus norvegicus]:Wild
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kadowaki, Masaaki; Ootani, Emi; Sugihara, Narumi; Furuno, Koji
Biological and Pharmaceutical Bulletin, 2005 , vol. 28, # 8 p. 1509 - 1513 Title/Abstract Full Text View citing articles Show Details
1
TGI
>
1000
µM
Biological and pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo
Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details
3.31
MIC
=
83
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
1
GI50
>
1000
µM
Inhibitor
Biological and pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo
Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details
4.46
IC50
~
35
µM
Inhibitor
DRLh-84
Biological and Pharmaceu...
cell line
Title/Abstract Full Text View citing articles Show Details
Isuzugawa; Ogihara; Inoue
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details
2.41
MIC
=
667
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
4.46
IC50
~
35
µM
Inhibitor
HL60RG cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Isuzugawa; Ogihara; Inoue
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details
2.03
MIC
=
1600
µg/mL
Inhibitor
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.63
MIC
=
400
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
=
500
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
4.46
IC50
~
35
µM
Inhibitor
KB
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Isuzugawa; Ogihara; Inoue
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details
3.11
MIC
=
133
µg/mL
Inhibitor
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.5
MIC
=
533
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.03
MIC
=
1600
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
2.8
MIC
=
267
µg/mL
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details
4.2
IC50
=
63
µM
Inhibitor
peritoneal macrophage
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kageura, Tadashi; Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Harima, Shoichi; Oda, Mamiko; Yoshikawa, Masayuki
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 7 p. 1887 - 1893 Title/Abstract Full Text View citing articles Show Details
5.74
IC50
=
1.8
µM
Inhibitor
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
10
µM
Inhibitor
xanthine dehydrogenase:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details
% Inhibition
ND
Inhibitor
xanthine dehydrogenase:Wild
= 20 µm
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
0
%
Inhibitor
xanthine dehydrogenase:Wild
= 20 µm
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details
Activity
=
3.9
µM
Inhibitor
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details
Vmax
=
0
µM/min
Radioligand (/ligand)
Polyphenol oxidase, chloroplastic [Camellia sinensis]:Wild
Phytochemistry, 1973 , ...
Title/Abstract Full Text Show Details
Prostaglandin G/H synthase 2:Wild
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
PHILIP COGGON; GERALD A MOSS; GARY W SANDERSON
Phytochemistry, 1973 , vol. 12, # 8 p. 1947 - 1955 Title/Abstract Full Text Show Details
% Inhibition
>
30
%
Huss; Ringbom; Perera; Bohlin; Vasaenge
Journal of Natural Products, 2002 , vol. 65, # 11 p. 1517 - 1521 Title/Abstract Full Text View citing articles Show Details
Activity
0
Phytochemistry, 1971 , ...
Title/Abstract Full Text Show Details
Squalene monooxygenase [Rattus norvegicus]:Wild
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
P. V. SUBBA RAO; B. FRITIG; J. R. VOSE; G. H. N. TOWERS
Phytochemistry, 1971 , vol. 10, # 1 p. 51 - 56 Title/Abstract Full Text Show Details
4.14
IC50
=
73
µM
Inhibitor
Abe; Kashiwagi; Noguchi; Tanaka; Ikeshiro; Kashiwada
Journal of Natural Products, 2001 , vol. 64, # 8 p. 1010 - 1014 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
5000
ng/mL
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Verotta, Luisella; Dell'Agli, Mario; Giolito, Andrea; Guerrini, Marco; Cabalion, Pierre; Bosisio, Enrica
Journal of Natural Products, 2001 , vol. 64, # 5 p. 603 - 607 Title/Abstract Full Text View citing articles Show Details
4.75
IC50
=
17.6
µM
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Kyriakopoulou; Magiatis; Skaltsounis; Aligiannis; Harvala
Journal of Natural Products, 2001 , vol. 64, # 8 p. 1095 - 1097 Title/Abstract Full Text View citing articles Show Details
Polyphenol oxidase, chloroplastic [Camellia sinensis]:Wild
Phytochemistry, 1973 , ...
Title/Abstract Full Text Show Details
Polyphenol oxidase, chloroplastic [Camellia sinensis]:Wild
Phytochemistry, 1973 , ...
Title/Abstract Full Text Show Details
DNA topoisomerase 1 [taurine cattle]:Wild
thymus
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
PHILIP COGGON; GERALD A MOSS; GARY W SANDERSON
Phytochemistry, 1973 , vol. 12, # 8 p. 1947 - 1955 Title/Abstract Full Text Show Details
Km
=
0.8
M
PHILIP COGGON; GERALD A MOSS; GARY W SANDERSON
Phytochemistry, 1973 , vol. 12, # 8 p. 1947 - 1955 Title/Abstract Full Text Show Details
1
IC50
>
1000
mM
Inhibitor
Suzuki, Keitarou; Yahara, Shoji; Hashimoto, Fumio; Uyeda, Masaru
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 9 p. 1088 - 1090 Title/Abstract Full Text View citing articles Show Details
IC50
=
196
mM
Inhibitor
DNA topoisomerase 2 [human]:Wild
Placental cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Suzuki, Keitarou; Yahara, Shoji; Hashimoto, Fumio; Uyeda, Masaru
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 9 p. 1088 - 1090 Title/Abstract Full Text View citing articles Show Details
Activity
@
Inhibitor
Nuclear factor NFkappa-B p105 subunit [Escherichia coli]:Wild
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Sharma, Rakesh K.; Pande, Vineet; Ramos, Maria J.; Rajor, Hament K.; Chopra, Shilpa; Meguro, Kazuyuki; Inoue, Jun-Ichiro; Otsuka, Masami
Bioorganic Chemistry, 2005 , vol. 33, # 2 p. 67 - 81 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
8.2
%
Biochemical and Biophysi...
Title/Abstract Full Text View citing articles Show Details
Mizushina, Yoshiyuki; Saito, Akiko; Tanaka, Akira; Nakajima, Noriyuki; Kuriyama, Isoko; Takemura, Masaharu; Takeuchi, Toshifumi; Sugawara, Fumio; Yoshida, Hiromi
Biochemical and Biophysical Research Communications, 2005 , vol. 333, # 1 p. 101 - 109 Title/Abstract Full Text View citing articles Show Details
Activity
ND
hydroquinone glucosyltransferase [Escherichia coli]:Wild
Bioorganic and medicinal...
Title/Abstract Full Text Show Details
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Hefner, Tobias; Arend, Joachim; Warzecha, Heribert; Siems, Karsten; Stoeckigt, Joachim
Bioorganic and medicinal chemistry, 2002 , vol. 10, # 6 p. 1731 - 1741 Title/Abstract Full Text Show Details
MBC
ND
Inhibitor
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
MIC
ND
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
1
MBC
>
3200
µg/mL
Inhibitor
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
3200
µg/mL
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
MBC
ND
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
MBC
ND
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
1.73
MIC
=
3200
µg/mL
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
MBC
ND
Inhibitor
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
MIC
ND
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
3200
µg/mL
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details
%
=
133
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
%
=
133
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
3.69
Ki
=
0.206
mM
20S Proteasome [human]:Wild
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details
4.41
Ki
=
0.039
mM
20S Proteasome [human]:Wild
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details
Activity
=
3.52
M
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Perez-Garrido, Alfonso; Helguera, Aliuska Morales; Morillas Ruiz, Juana M.; Zafrilla Rentero, Pilar
European Journal of Medicinal Chemistry, 2012 , vol. 49, p. 86 - 94 Title/Abstract Full Text View citing articles Show Details
%
=
110
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
%
=
159
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
2.57
Ki
=
2.722
mM
20S Proteasome [human]:Wild
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details
%
=
155
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
%
=
162
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
%
=
119
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
3.83
Ki
=
0.148
mM
20S Proteasome [human]:Wild
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details
%
=
142
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
3.24
Ki
=
0.578
mM
20S Proteasome [human]:Wild
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details
4.6
Ki
=
0.025
mM
20S Proteasome [human]:Wild
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details
%
=
118
%
Current Topics in Medici...
Title/Abstract Full Text View citing articles Show Details
Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju
Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details
EC50
=
11.72
M
Inhibitor
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Nadal, Brice; Thetiot-Laurent, Sophie A.-L.; Pin, Serge; Renault, Jean-Philippe; Cressier, Damien; Rima, Ghassoub; Le Roux, Antoine; Meunier, Stephane; Wagner, Alain; Lion, Claude; Le Gall, Thierry
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 22 p. 7931 - 7939
Title/Abstract Full Text View citing articles Show Details
1
Kid
NA
Protease [Human immunodeficiency virus 1]:Wild
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Flausino Jr.; Dufau; Regasini; Petrônio; Silva; Rose; Bolzani; Reboud-Ravaux
Current Medicinal Chemistry, 2012 , vol. 19, # 26 p. 4534 - 4540 Title/Abstract Full Text View citing articles Show Details
Activity
=
1.36
nM
Inhibitor
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Nadal, Brice; Thetiot-Laurent, Sophie A.-L.; Pin, Serge; Renault, Jean-Philippe; Cressier, Damien; Rima, Ghassoub; Le Roux, Antoine; Meunier, Stephane; Wagner, Alain; Lion, Claude; Le Gall, Thierry
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 22 p. 7931 - 7939 Title/Abstract Full Text View citing articles Show Details
Activity
1.78
Copper Ion Binding / Oxidoreductase [Escherichia coli]:Wild
Patent: WO2007/63614 A...
Title/Abstract Full Text Show Details
NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY; MANDOM Corporation; OTSUKA, Kaori; TSUJINO, Yoshio; KONNO, Yusuke; KUROSE, Shinji; KATAOKA, Kunishige; SAKURAI, Takeshi
Patent: WO2007/63614 A1, 2007 ; Title/Abstract Full Text Show Details
Activity
5.17
Copper Ion Binding / Oxidoreductase [Escherichia coli]:Wild
Patent: WO2007/63614 A...
Title/Abstract Full Text Show Details
NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY; MANDOM Corporation; OTSUKA, Kaori; TSUJINO, Yoshio; KONNO, Yusuke; KUROSE, Shinji; KATAOKA, Kunishige; SAKURAI, Takeshi
Patent: WO2007/63614 A1, 2007 ; Title/Abstract Full Text Show Details
Activity
=
93.4
%
Brain cortical neuron cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
58.3
%
Inhibitor
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
0
%
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
Activity
=
22.6
µmol/mg protein
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
2.92
µmol/mg protein
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Ratio
2.77
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
pX
Parameter
Value (qual)
Value (quant)
Unit
Activity
=
21.27
%
Action on Target
Target
Tissue/Organ
Cell
Bioassay
Dose
Effect
GMK-AH-1 cell line
Reference (expand all/collapse all) Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
Activity
=
27
%
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
22
%
Inhibitor
Tyrosinase [Mus musculus]:Wild
B16
= 50 µm
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
0
%
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
36.77
%
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
41.21
%
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
Activity
=
69.6
%
Brain cortical neuron cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details
Activity
=
15.2
%
Inhibitor
Brain cortical neuron cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details
Survival activity
=
59.7
%
B103 cell line
Biological and pharmaceu...
Title/Abstract Full Text Show Details
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Mook-Jung, Inhee; Kim, Hee; Fan, Wenzhe; Tezuka, Yasuhiro; Kadota, Shigetoshi; Nishijo, Hisao; Jung, Min Whan
Biological and pharmaceutical bulletin, 2002 , vol. 25, # 8 p. 1101 - 1104 Title/Abstract Full Text Show Details
1
CC50
>
1000
µM
Inhibitor
GMK-AH-1 cell line
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
Activity
=
0
%
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
33.9
%
Inhibitor
Tyrosinase [Mus musculus]:Wild
B16
= 25 µm
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
20.1
%
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
%
=
99.1
%
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
0
%
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
Activity
=
67.1
µmol/mg protein
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
42.5
µmol/mg protein
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
0
%
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
Activity
=
0.38
µM
Brain cortical neuron cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details
Ratio
19.1
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
%
=
90.6
%
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
4
IC50
=
0.0001
M
Inhibitor
aromatase [Rattus norvegicus]:Wild
ovary cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Satoh, Kanako; Nonaka, Rhouichi; Ishikawa, Fusako; Ogata, Akio; Nagai, Fumiko
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 3 p. 357 - 362 Title/Abstract Full Text View citing articles Show Details
5.44
IC50
=
3.59E06
M
Inhibitor
Tyrosinase [mushroom]:Wild
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
%
=
98.3
%
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
33.6
%
Inhibitor
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
84.7
%
Inhibitor
Brain cortical neuron cell
Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
29.5
%
Inhibitor
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
4.47
IC50
=
33.56
µM
Inhibitor
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
4.19
IC50
=
64.35
µM
Inhibitor
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
Activity
=
0.6
µM
Brain cortical neuron cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
2.21
%
Inhibitor
Tyrosinase [Mus musculus]:Wild
B16
= 200 µm
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
71.5
%
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
4.88
IC50
=
13.16
µM
Inhibitor
GMK-AH-1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details
Ratio
33.6
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Inhibitor
aryl hydrocarbon receptor [mammal]:Wild
Amakura, Yoshiaki; Tsutsumi, Tomoaki; Sasaki, Kumiko; Yoshida, Takashi; Maitani, Tamio
Biological and Pharmaceutical Bulletin, 2003 , vol. 26, # 12 p. 1754 - 1760 Title/Abstract Full Text View citing articles Show Details
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Activity
=
30
%
Inhibitor
Brain cortical neuron cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details
Activity
=
5.93
µmol/mg protein
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
39
%
Inhibitor
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
4.04
µmol/mg protein
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
21.4
%
Inhibitor
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Ratio
10.8
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
33.4
%
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
48.4
µM
Brain cortical neuron cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details
4.47
IC50
=
3.4E-05
M
Inhibitor
aromatase [Rattus norvegicus]:Wild
ovary cell
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Satoh, Kanako; Nonaka, Rhouichi; Ishikawa, Fusako; Ogata, Akio; Nagai, Fumiko
Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 3 p. 357 - 362 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
6.89
%
Inhibitor
Tyrosinase [Mus musculus]:Wild
B16
= 100 µm
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
96.2
µmol/mg protein
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
Activity
=
3.52
µmol/mg protein
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
42.6
%
Inhibitor
Tyrosinase [Mus musculus]:Wild
B16
= 10 µm
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
%
=
93.5
%
B16
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kim, You-Jung
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details
%
=
79
%
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details
%
=
80
%
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details
4.17
ID50
=
11.6
µg/mL
Inhibitor
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Okuda; Kimura; Yoshida; Hatano; Arichi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631 Title/Abstract Full Text View citing articles Show Details
Activity
=
15.2
µeq/g
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details
3.95
ID50
=
19
µg/mL
Inhibitor
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Okuda; Kimura; Yoshida; Hatano; Arichi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631
Title/Abstract Full Text View citing articles Show Details
Activity
=
8.6
µeq/g
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
19
%
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Okuda; Kimura; Yoshida; Hatano; Arichi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631 Title/Abstract Full Text View citing articles Show Details
ZI
=
7
mm
Phytochemistry, 2005 , ...
Title/Abstract Full Text View citing articles Show Details
Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard
Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details
ZI
=
7
mm
Phytochemistry, 2005 , ...
Title/Abstract Full Text View citing articles Show Details
Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard
Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details
% Inhibition
40 - 50
%
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details
Activity
=
11.9
µeq/g
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
500
µM
Inhibitor
E-selectin [human]:Wild
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details
Activity
=
77
%
Phenylalanine ammonia-lyase [cucumber]:Wild
Phytochemistry, 1974 , ...
Title/Abstract Full Text Show Details
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
SUSAN E. IREDALE; HARRY SMITH
Phytochemistry, 1974 , vol. 13, # 3 p. 575 - 583 Title/Abstract Full Text Show Details
Activity
=
8.8
µeq/g
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details
%
=
59
%
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
50
%
Inhibitor
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Okuda; Kimura; Yoshida; Hatano; Arichi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631 Title/Abstract Full Text View citing articles Show Details
Activity
=
3.9
µM
Inhibitor
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Matsuda; Ohta; Kawaguchi; Yoshikawa
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 1 p. 69 - 72 Title/Abstract Full Text View citing articles Show Details
Activity
=
8.7
µeq/g
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details
%
=
82
%
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
20
%
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Okuda; Kimura; Yoshida; Hatano; Arichi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631 Title/Abstract Full Text View citing articles Show Details
4.38
IC50
=
7.1
µg/mL
Inhibitor
xanthine dehydrogenase:Wild
Phytochemistry, 2005 , ...
Title/Abstract Full Text View citing articles Show Details
Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard
Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details
% Inhibition
ND
HL-60 cell line
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details
%
=
84
%
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details
Activity
=
8.3
µeq/g
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506
Title/Abstract Full Text View citing articles Show Details
%
=
103
%
adipocyte
Chemical and pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Kimura; Okuda; Yoshida; Hatano; Arichi
Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details
% Inhibition
ND
HL-60 cell line
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details
ZI
=
7
mm
Phytochemistry, 2005 , ...
Title/Abstract Full Text View citing articles Show Details
Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard
Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details
ZI
=
13
mm
Phytochemistry, 2005 , ...
Title/Abstract Full Text View citing articles Show Details
Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard
Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details
4.72
IC50
=
19.1
µM
Inhibitor
P-selectin [human]:Wild
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details
4.56
IC50
=
27.6
µM
Inhibitor
L-selectin [human]:Wild
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
33
%
Inhibitor
Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Fan; Tezuka; Ni; Kadota
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 4 p. 396 - 401 Title/Abstract Full Text View citing articles Show Details
%
=
65
%
MDA-MB231
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Gomes, Catarina A.; Girao Da Cruz, Teresa; Andrade, Jose L.; Milhazes, Nuno; Borges, Fernanda; Marques, M. Paula M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5395 - 5401 Title/Abstract Full Text View citing articles Show Details
%
=
50
%
MOLT-3 cell line
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Gomes, Catarina A.; Girao Da Cruz, Teresa; Andrade, Jose L.; Milhazes, Nuno; Borges, Fernanda; Marques, M. Paula M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5395 - 5401 Title/Abstract Full Text View citing articles Show Details
%
=
74
%
HeLa cell
Journal of Medicinal Che...
line
Title/Abstract Full Text View citing articles Show Details
Gomes, Catarina A.; Girao Da Cruz, Teresa; Andrade, Jose L.; Milhazes, Nuno; Borges, Fernanda; Marques, M. Paula M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5395 - 5401 Title/Abstract Full Text View citing articles Show Details
4.43
IC50
=
6.3
µg/mL
Antioxidant
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Yoshimura, Morio; Yamakami, Saori; Amakura, Yoshiaki; Yoshida, Takashi
Journal of Natural Products, 2012 , vol. 75, # 10 p. 1798 - 1802 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
50
µM
Inhibitor
Pancreatic triacylglycerol lipase:Wild
Patent: WO2006/22227 A...
Title/Abstract Full Text Show Details
%
Inhibitor
DIIodophenylpyruvate Reductase [taurine cattle]:Wild
heart
The Journal of biologica...
Title/Abstract Full Text View citing articles Show Details
SUNTORY LIMITED
Patent: WO2006/22227 A1, 2006 ; Title/Abstract Full Text Show Details
% Inhibition
<
5
Zannoni; Weber
The Journal of biological chemistry, 1966 , vol. 241, # 6 p. 1340 - 1344 Title/Abstract Full Text View citing articles Show Details
3.13
MIC
=
125
µg/mL
Letters in Applied Micro...
Title/Abstract Full Text Show Details
Archives of Biochemistry...
Title/Abstract Full Text View citing articles Show Details
Bisignano; Sanogo; Marino; Aquino; D'Angelo; Germano; De Pasquale; Pizza
Letters in Applied Microbiology, 2000 , vol. 30, # 2 p. 105 - 108 Title/Abstract Full Text Show Details
1
IC50
>
0.25
mM
Ueda, Jun-Ichi; Saito, Natuko; Shimazu, Yoshie; Ozawa, Toshihiko
Archives of Biochemistry and Biophysics, 1996 , vol. 333, # 2 p. 377 - 384 Title/Abstract Full Text View citing articles Show Details
4
ID50
=
100
µM
Ribonucleosidediphosphate reductase [Rattus norvegicus]:Wild
NOVIKOFF HEPATOMA CELL LINE
Cancer Research, 1979 , ...
Title/Abstract Full Text Show Details
Reverse transcriptase [Human immunodeficiency virus 1]:Wild
AIDS Research and Human ...
Title/Abstract Full Text Show Details
Letters in Applied Micro...
Title/Abstract Full Text Show Details
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Elford; Wampler; Van 'T Riet
Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details
1
ID50
>
588
µM
Ogata; Higuchi; Mochida; Matsumoto; Kato; Endo; Kaji
AIDS Research and Human Retroviruses, 1992 , vol. 8, # 11 p. 1937 - 1944 Title/Abstract Full Text Show Details
4.64
MIC
=
3.9
µg/mL
Bisignano; Sanogo; Marino; Aquino; D'Angelo; Germano; De Pasquale; Pizza
Letters in Applied Microbiology, 2000 , vol. 30, # 2 p. 105 - 108 Title/Abstract Full Text Show Details
MIC
ND
Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais
Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
100
µg/mL
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais
Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details
4.64
MIC
=
3.9
µg/mL
Letters in Applied Micro...
Title/Abstract Full Text Show Details
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Bisignano; Sanogo; Marino; Aquino; D'Angelo; Germano; De Pasquale; Pizza
Letters in Applied Microbiology, 2000 , vol. 30, # 2 p. 105 - 108 Title/Abstract Full Text Show Details
MIC
ND
Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais
Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details
MIC
ND
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais
Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
Inhibitor
Poly(ADP-ribose) glycohydrolase [Mus musculus]:Wild
34i cell line
Journal of Biological Ch...
Title/Abstract Full Text Show Details
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Tsai; Aoki; Maruta; Abe; Sakagami; Hatano; Okuda; Tanuma
Journal of Biological Chemistry, 1992 , vol. 267, # 20 p. 14436 - 14442 Title/Abstract Full Text Show Details
3.53
MIC
=
50
µg/mL
Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais
Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details
3.13
MIC
=
125
µg/mL
Letters in Applied Micro...
Title/Abstract Full Text Show Details
Bisignano; Sanogo; Marino; Aquino; D'Angelo; Germano; De Pasquale; Pizza
Letters in Applied Microbiology, 2000 , vol. 30, # 2 p. 105 - 108 Title/Abstract Full Text Show Details
Inhibition Score
5
Ribonucleosidediphosphate reductase [Rattus norvegicus]:Wild
NOVIKOFF HEPATOMA CELL LINE
Cancer Research, 1979 , ...
Title/Abstract Full Text Show Details
Archives of Biochemistry...
Title/Abstract Full Text View citing articles Show Details
Elford; Wampler; Van 'T Riet
Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details
1
IC50
>
0.1
mM
Ueda, Jun-Ichi; Saito, Natuko; Shimazu, Yoshie; Ozawa, Toshihiko
Archives of Biochemistry and Biophysics, 1996 , vol. 333, # 2 p. 377 - 384 Title/Abstract Full Text View citing articles Show Details
Activity
=
0
%
Current medicinal chemis...
Title/Abstract Full Text Show Details
Mehta, Rajendra G; Naithani, Rajesh; Huma, Loredana; Hawthorne, Michael; Moriarty, Robert M; McCormick, David L; Steele, Vernon E; Kopelovich, Levy
Current medicinal chemistry, 2008 , vol. 15, # 27 p. 2785 - 2825 Title/Abstract Full Text Show Details
3.4
pGI50
3.4
Inhibitor
MEL
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
3.3
pGI50
3.3
Inhibitor
cancer cell line
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
3.5
pGI50
3.5
Inhibitor
OVCAR cell line
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
3.3
pGI50
3.3
Inhibitor
small cell lung cancer cell line
leukemia cell line
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
3.4
pGI50
3.4
Inhibitor
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
3.5
pGI50
3.5
Inhibitor
lung nonsmall cell carcinoma cell line
RENAL CANCER CELL LINE
CNS CANCER CELL LINE
PROSTATE CANCER CELL LINE
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
3.5
pGI50
3.5
Inhibitor
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
3.4
pGI50
3.4
Inhibitor
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
3.3
pGI50
3.3
Inhibitor
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
50
%
Inhibitor
Estradiol 17-betadehydrogenase 2 [human]:Wild
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Poirier, Donald
Current Medicinal Chemistry, 2003 , vol. 10, # 6 p. 453 - 477 Title/Abstract Full Text View citing articles Show Details
3.4
pGI50
3.4
Inhibitor
breast cancer cell line
Current Pharmaceutical D...
Title/Abstract Full Text View citing articles Show Details
Ren, Steven S.; Lien, Eric J.
Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
50
%
Inhibitor
Estradiol 17-betadehydrogenase 2:Wild
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Poirier, Donald
Current Medicinal Chemistry, 2003 , vol. 10, # 6 p. 453 - 477 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
Inhibitor
Tyrosinase [mushroom]:Wild
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Chen, Lih-Geeng; Chang, Wei-Ling; Lee, Chia-Jung; Lee, Lain-Tze; Shih, Chwen-Ming; Wang, Ching-Chiung
Biological and Pharmaceutical Bulletin, 2009 , vol. 32, # 8 p. 1447 - 1452 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
6.26
%
Inhibitor
Tyrosinase [mushroom]:Wild
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Chen, Lih-Geeng; Chang, Wei-Ling; Lee, Chia-Jung; Lee, Lain-Tze; Shih, Chwen-Ming; Wang, Ching-Chiung
Biological and Pharmaceutical Bulletin, 2009 , vol. 32, # 8 p. 1447 - 1452 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
4
MIC
=
100
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
4
MIC
100
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
3.9
MIC
=
125
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details
6.15
EC50
=
0.7
µM
trachea
Medicinal Research Revie...
Title/Abstract Full Text View citing articles Show Details
Calixto, Joao B.; Santos, Adair R. S.; Cechinel Filho, Valdir; Yunes, Rosendo A.
Medicinal Research Reviews, 1998 , vol. 18, # 4 p. 225 - 258 Title/Abstract Full Text View citing articles Show Details
Activity
=
3
mM
Inhibitor
Signal Transducer And Activator Of Transcription 1, 91kDa:Wild
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Carcereri de Prati, Alessandra; Ciampa, Anna Rosa; Cavalieri, Elisabetta; Zaffini, Raffaela; Darra, Elena; Menegazzi, Marta; Suzuki, Hisanori; Mariotto, Sofia
Current Medicinal Chemistry, 2005 , vol. 12, # 16 p. 1819 - 1828 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
18.79
%
Cytochrome P450 2E1 [human]:Wild
NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho
Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details
Patent: WO2010/9572 A1...
Title/Abstract Full Text Show Details
Activity
9.62
radical scavenging
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
%
=
92.1
%
thrombocyte
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
%
=
91.9
%
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
Concentration
=
55.4
µM
Antioxidant
Pharmaceutical Chemistry...
Title/Abstract Full Text View citing articles Show Details
Agadzhanyan; Oganesyan; Abaev
Pharmaceutical Chemistry Journal, 2010 , vol. 44, # 7 p. 360 - 365 Title/Abstract Full Text View citing articles Show Details
Tlag
=
0.018
minute
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
10.5
%
Cytochrome P450 2E1 [human]:Wild
Patent: WO2010/9572 A1...
Title/Abstract Full Text Show Details
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho
Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details
Tlag
=
0.012
minute
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
%
=
90.6
%
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
%
=
88.5
%
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
35.59
%
Cytochrome P450 2E1 [human]:Wild
NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho
Patent: WO2010/9572 A1...
Title/Abstract Full Text Show Details
Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details
Activity
ND
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Yanovsky, Inessa; Finkin-Groner, Efrat; Zaikin, Andrey; Lerman, Lena; Shalom, Hila; Zeeli, Shani; Weill, Tehilla; Ginsburg, Isaac; Nudelman, Abraham; Weinstock, Marta
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10700 - 10715 Title/Abstract Full Text View citing articles Show Details
Tlag
=
0.012
minute
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
Activity
=
31.4
%
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Yanovsky, Inessa; Finkin-Groner, Efrat; Zaikin, Andrey; Lerman, Lena; Shalom, Hila; Zeeli, Shani; Weill, Tehilla; Ginsburg, Isaac; Nudelman, Abraham; Weinstock, Marta
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10700 - 10715 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
48.24
%
Cytochrome P450 2E1 [human]:Wild
Patent: WO2010/9572 A1...
Title/Abstract Full Text Show Details
Patent: WO2010/9572 A1...
Title/Abstract Full Text Show Details
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho
Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details
% Inhibition
=
42.74
%
Cytochrome P450 2E1 [human]:Wild
NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho
Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details
%
=
84.8
%
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
%
=
93.7
%
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
27.96
%
Cytochrome P450 2E1 [human]:Wild
Patent: WO2010/9572 A1...
Title/Abstract Full Text Show Details
scavenging
Phytochemistry, 2012 , ...
Title/Abstract Full Text View citing articles Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho
Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details
EC1
=
170
µM
Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.
Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details
%
=
81.5
%
thrombocyte
Antithrombotic
Bioorganic Chemistry, 20...
Title/Abstract Full Text View citing articles Show Details
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
2.95
IC50
1.12
mM
scavenging
Phytochemistry, 2012 , ...
Title/Abstract Full Text View citing articles Show Details
Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.
Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details
%
=
56
%
scavenging
Phytochemistry, 2012 , ...
Title/Abstract Full Text View citing articles Show Details
Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.
Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details
5.49
IC50
=
3.24
µM
scavenging
Phytochemistry, 2012 , ...
Title/Abstract Full Text View citing articles Show Details
Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.
Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details
3.66
IC50
~
216.6
µM
Inhibitor
MCF7
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Sharma, Anupama; Gautam, Surya Prakash; Gupta, Arun Kumar
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 11 p. 3341 - 3346 Title/Abstract Full Text View citing articles Show Details
IC50
=
75.4
µg
Inhibitor
hydrogen:potassiumexchanging ATPase:Wild
Patent: WO2007/113855 ...
Title/Abstract Full Text Show Details
Carbonic anhydrase 6 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH
Patent: WO2007/113855 A1, 2007 ; Title/Abstract Full Text Show Details
5.21
Ki
=
6.13
µM
Inhibitor
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
5.16
Ki
=
6.99
µM
Inhibitor
Carbonic anhydrase 9 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
6
%
Inhibitor
hydrogen:potassiumexchanging ATPase:Wild
Patent: WO2007/113855 ...
Title/Abstract Full Text Show Details
THP-1 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH
Patent: WO2007/113855 A1, 2007 ; Title/Abstract Full Text Show Details
Activity
ND
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
5.65
Ki
=
2.25
µM
Inhibitor
Carbonic anhydrase 2 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
%
=
18.23
%
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
5.01
Ki
=
9.86
µM
Inhibitor
Carbonic anhydrase 13 [Mus musculus]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
5.22
Ki
=
6.07
µM
Inhibitor
Carbonic anhydrase 7 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
%
=
90.83
%
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
5.01
Ki
=
9.8
µM
Inhibitor
Carbonic anhydrase 4 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
Activity
ND
THP-1 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
%
=
38.42
%
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
5
Ki
=
9.97
µM
Inhibitor
Carbonic anhydrase 5B, mitochondrial [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
5.15
Ki
=
7.03
µM
Inhibitor
Carbonic anhydrase 14 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
5.13
Ki
=
7.49
µM
Inhibitor
Carbonic anhydrase 3 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
%
=
22.68
%
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
%
=
46.9
%
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
IC50
=
1.12
µg
Inhibitor
hydrogen:potassiumexchanging ATPase:Wild
Patent: WO2007/113855 ...
Title/Abstract Full Text Show Details
THP-1 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH
Patent: WO2007/113855 A1, 2007 ; Title/Abstract Full Text Show Details
Activity
ND
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
5.39
Ki
=
4.08
µM
Inhibitor
Carbonic anhydrase 5 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
%
=
19.45
%
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
5.49
Ki
=
3.2
µM
Inhibitor
Carbonic anhydrase 1 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
5.11
Ki
=
7.78
µM
Inhibitor
Carbonic anhydrase 12 [human]:Wild
= 10 mM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details
pID50
-1.48
Farmaco, 2000 , vol. 55...
Title/Abstract Full Text View citing articles Show Details
Krogh; Yunes; Andricopulo
Farmaco, 2000 , vol. 55, # 11-12 p. 730 - 735 Title/Abstract Full Text View citing articles Show Details
ID50
=
30.4
µM/kg
Farmaco, 2000 , vol. 55...
Title/Abstract Full Text View citing articles Show Details
Krogh; Yunes; Andricopulo
Farmaco, 2000 , vol. 55, # 11-12 p. 730 - 735 Title/Abstract Full Text View citing articles Show Details
4.2
IC50
=
63
µM
Inhibitor
peritoneal macrophage
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Matsuda, Hisashi; Kageura, Tadashi; Morikawa, Toshio; Toguchida, Iwao; Harima, Shoichi; Yoshikawa, Masayuki
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 4 p. 323 - 327 Title/Abstract Full Text View citing articles Show Details
1
Cytotoxic Score
NA
peritoneal macrophage
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Matsuda, Hisashi; Kageura, Tadashi; Morikawa, Toshio; Toguchida, Iwao; Harima, Shoichi; Yoshikawa, Masayuki
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 4 p. 323 - 327 Title/Abstract Full Text View citing articles Show Details
5.81
IC50
=
1.55
µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Gupta, Sunil; Matthew, Susan; Abreu, Pedro M.; Aires-De-Sousa, Joao
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 4 p. 1199 - 1206 Title/Abstract Full Text View citing articles Show Details
ED50
=
18.9
mg/kg bw
Journal of Biological Ch...
Title/Abstract Full Text View citing articles Show Details
Pal, Chinmay; Bindu, Samik; Dey, Sumanta; Alam, Athar; Goyal, Manish; Iqbal, Mohd Shameel; Sarkar, Souvik; Kumar, Rahul; Halder, Kamal Krishna; Debnath, Mita Chatterjee; Adhikari, Susanta; Bandyopadhyay, Uday
Journal of Biological Chemistry, 2012 , vol. 287, # 5 p. 3495 - 3509 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1
mM
Inhibitor
Alpha-amylase [human]:Wild
Patent: US5318986 A1, ...
Title/Abstract Full Text Show Details
µM
Inhibitor
Nuclear factor NFkappa-B p105 subunit:Wild
ChemMedChem, 2009 , vol...
Title/Abstract Full Text View citing articles Show Details
Mitsui Norin Co., Ltd.
Patent: US5318986 A1, 1994 ; Title/Abstract Full Text Show Details
4
IC50
100 200
Piccagli, Laura; Fabbri, Enrica; Borgatti, Monica; Bianchi, Nicoletta; Bezzerri, Valentino; Mancini, Irene; Nicolis, Elena; Dechecchi, Cristina M.; Lampronti, Ilaria; Cabrini, Giulio; Gambari, Roberto
ChemMedChem, 2009 , vol. 4, # 12 p. 2024 - 2033 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1
mM
Inhibitor
Nuclear factor NFkappa-B p105 subunit:Wild
ChemMedChem, 2009 , vol...
Title/Abstract Full Text View citing articles Show Details
Piccagli, Laura; Fabbri, Enrica; Borgatti, Monica; Bianchi, Nicoletta; Bezzerri, Valentino; Mancini, Irene; Nicolis, Elena; Dechecchi, Cristina M.; Lampronti, Ilaria; Cabrini, Giulio; Gambari, Roberto
ChemMedChem, 2009 , vol. 4, # 12 p. 2024 - 2033 Title/Abstract Full Text View citing articles Show Details
%
ND
radical scavenging
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details
%
=
97.14
%
radical scavenging
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details
5.74
IC50
=
1.83
µM
radical scavenging
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details
5.22
IC50
=
6
µM
radical scavenging
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details
3.31
IC50
=
487
µM
Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild
Nuclear factor NFkappa-B p105 subunit:Wild
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Orhan, I. Erdogan
Current Medicinal Chemistry, 2012 , vol. 19, # 14 p. 2252 - 2261 Title/Abstract Full Text View citing articles Show Details
3.3
IC50
<C
500
µM
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Cabrini; Bezzerri; Mancini; Nicolis; Dechecchi; Tamanini; Lampronti; Piccagli; Bianchi; Borgatti; Gambari
Current Medicinal Chemistry, 2010 , vol. 17, # 35 p. 4392 - 4404 Title/Abstract Full Text View citing articles Show Details
%
ND
radical scavenging
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
Inhibitor
Reverse transcriptase [Human immunodeficiency virus 1]:Mutated
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Tillekeratne; Sherette; Grossman; Hupe; Hudson
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 20 p. 2763 - 2767 Title/Abstract Full Text View citing articles Show Details
IC50
ND
Inhibitor
RNA-directed DNA polymerase:Mutated
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Tillekeratne; Sherette; Grossman; Hupe; Hudson
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 20 p. 2763 - 2767 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
Inhibitor
RNA-directed DNA polymerase:Mutated
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Tillekeratne; Sherette; Grossman; Hupe; Hudson
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 20 p. 2763 - 2767 Title/Abstract Full Text View citing articles Show Details
%
=
41
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
Mini-Reviews in Medicina...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
%
=
88.9
%
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
5.39
EC50
=
4.1
µM
Matkowski, Adam; Kus, Piotr; Goralska, Edyta; Wozniak, Dorota
Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 439 - 455 Title/Abstract Full Text View citing articles Show Details
pX
Parameter
Value (qual)
IC50
ND
Value (quant)
Unit
Action on Target
Target
Tissue/Organ
Cell
Bioassay
Dose
Effect
Carbonic anhydrase 2 [human]:Wild
Reference (expand all/collapse all) Mini-Reviews in Medicina...
Title/Abstract Full Text View citing articles Show Details
Guelcin, Ilhami; Beydemir, Suekrue
Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 408 - 430 Title/Abstract Full Text View citing articles Show Details
3.41
IC50
=
387
µM
PLC/PRF/5 cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
IR-K562 cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
L929
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Antineoplastic
European Journal of Medi...
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
5.32
IC50
=
4.75
µM
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
3.6
IC50
=
250
µM
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
%
=
21.4
%
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
3.45
IC50
=
358
µM
HeLa cell
line
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
51
%
U-251MG cell line
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
RAW 264.7 cell line
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Yang, Zhi-Gang; Wen, Xiu-Feng; Li, Yong-Hai; Matsuzaki, Keiichi; Kitanaka, Susumu
Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 3 p. 279 - 285 Title/Abstract Full Text View citing articles Show Details
3.44
IC50
=
364
µM
DRLh-84 cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
%
=
34.4
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
%
=
73.6
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
5
IC50
10 - 50
µM
Calu-6 cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
%
=
21.4
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
4.4
IC50
=
40
µM
WEHI-231 cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
%
=
89.1
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
%
=
89.1
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
29
%
U-87
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
%
=
13.9
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
%
=
28
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
31
%
U-251MG cell line
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
5.12
IC50
=
1.28
µg/mL
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
4
IC50
100 200
µM
A-549
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
IC50
ND
Carbonic anhydrase 1 [human]:Wild
Mini-Reviews in Medicina...
Title/Abstract Full Text View citing articles Show Details
Guelcin, Ilhami; Beydemir, Suekrue
Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 408 - 430 Title/Abstract Full Text View citing articles Show Details
3.55
IC50
=
282
µM
P388D1 cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
3.52
IC50
300
µM
HL-60 cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
30
%
U-87
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
3.5
IC50
=
317
µM
HL60RG cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
%
=
15.8
%
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details
4.48
IC50
=
33
µM
K-562 cell line
Antineoplastic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
2.98
Ki
=
1.052
mM
Inhibitor
Carbonic anhydrase 1 [human]:Wild
erythrocyte
Chemical Biology and Dru...
Title/Abstract Full Text View citing articles Show Details
Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Chemical Biology and Drug Design, 2010 , vol. 75, # 5 p. 515 - 520 Title/Abstract Full Text View citing articles Show Details
3.12
Ki
=
0.758
mM
Inhibitor
Carbonic anhydrase 2 [human]:Wild
erythrocyte
Chemical Biology and Dru...
Title/Abstract Full Text View citing articles Show Details
Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.
Chemical Biology and Drug Design, 2010 , vol. 75, # 5 p. 515 - 520 Title/Abstract Full Text View citing articles Show Details
4.38
IC50
=
41.8
µM
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kanno, Syu-Ichi; Kakuta, Mai; Kitajima, Yasue; Osanai, Yuu; Kurauchi, Kaori; Ohtake, Takaharu; Ujibe, Mayuko; Uwai, Kouji; Takeshita, Mitsuhiro; Ishikawa, Masaaki
Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 5 p. 994 - 998 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
Inhibitor
NS3 Protease [Hepatitis C virus]:Wild
Antiviral Research, 2007...
Title/Abstract Full Text View citing articles Show Details
Zuo, Guoying; Li, Zhengquan; Chen, Lirong; Xu, Xiaojie
Antiviral Research, 2007 , vol. 76, # 1 p. 86 - 92 Title/Abstract Full Text View citing articles Show Details
2.77
IC50
=
1710
µM
Inhibitor
NS3 Protease [Hepatitis C virus]:Wild
Antiviral Research, 2007...
Title/Abstract Full Text View citing articles Show Details
Zuo, Guoying; Li, Zhengquan; Chen, Lirong; Xu, Xiaojie
Antiviral Research, 2007 , vol. 76, # 1 p. 86 - 92 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
50
µM
Inhibitor
L1210 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details
4.74
IC50
=
18.3
µM
Inhibitor
HL-60 cell line
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Murias, Marek; Jaeger, Walter; Handler, Norbert; Erker, Thomas; Horvath, Zsuzsanna; Szekeres, Thomas; Nohl, Hans; Gille, Lars
Biochemical Pharmacology, 2005 , vol. 69, # 6 p. 903 - 912 Title/Abstract Full Text View citing articles Show Details
%
=
90
%
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details
4.3
IC50
=
50
µM
Inhibitor
L1210 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
60.5
%
Inhibitor
arachidonate 15-lipoxygenase [soybean]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Russell, Wendy R.; Scobbie, Lorraine; Duthie, Garry G.; Chesson, Andrew
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 8 p. 4589 - 4593 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
50
µM
Inhibitor
CCRF-CEM cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
50
µM
Inhibitor
CCRF-CEM cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details
3.39
IC50
=
68.52
µg/mL
Inhibitor
NIH-3T3
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Seung, Chul Lee; Yong, Soo Kwon; Kyung, Hun Son; Hyun, Pyo Kim; Moon, Young Heo
Archives of Pharmacal Research, 2005 , vol. 28, # 7 p. 775 - 783 Title/Abstract Full Text View citing articles Show Details
5.34
IC50
=
0.78
µg/mL
NIH-3T3
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Seung, Chul Lee; Yong, Soo Kwon; Kyung, Hun Son; Hyun, Pyo Kim; Moon, Young Heo
Archives of Pharmacal Research, 2005 , vol. 28, # 7 p. 775 - 783
Title/Abstract Full Text View citing articles Show Details
3.39
IC50
=
69.18
µg/mL
NIH-3T3
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Seung, Chul Lee; Yong, Soo Kwon; Kyung, Hun Son; Hyun, Pyo Kim; Moon, Young Heo
Archives of Pharmacal Research, 2005 , vol. 28, # 7 p. 775 - 783 Title/Abstract Full Text View citing articles Show Details
% Inhibition
77 - 100
%
Matrix metalloproteinase14:Wild
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
% Inhibition
34 - 76
%
Matrix metalloproteinase9:Wild
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
4.43
IC50
=
37
µM
Neutrophil collagenase:Wild
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
% Inhibition
77 - 100
%
72kDa type IV collagenase:Wild
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
4.3
IC50
=
50
µM
Matrix metalloproteinase14:Wild
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
% Inhibition
34 - 76
%
Neutrophil collagenase:Wild
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
4.64
IC50
=
23
µM
Matrix metalloproteinase9:Wild
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
5.62
IC50
=
2.4
µM
72kDa type IV collagenase:Wild
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
Activation
1.3
Peroxisome proliferator-
CV-1 cell
Patent: US2009/176810 ...
activated receptor alpha [Cercopithecidae]:Wild
line
Title/Abstract Full Text Show Details
AMOREPACIFIC Corporation
Patent: US2009/176810 A1, 2009 ; Title/Abstract Full Text Show Details
Activation
1.7
Peroxisome proliferatoractivated receptor alpha [Cercopithecidae]:Wild
CV-1 cell line
Patent: US2009/176810 ...
Title/Abstract Full Text Show Details
%
Inhibitor
Cytochrome P450 3A1 [Rattus norvegicus]:Wild
Patent: US2003/166584 ...
Title/Abstract Full Text Show Details
Patent: US2003/166584 ...
Title/Abstract Full Text Show Details
Patent: US2006/69042 A...
Title/Abstract Full Text Show Details
AMOREPACIFIC Corporation
Patent: US2009/176810 A1, 2009 ; Title/Abstract Full Text Show Details
% Inhibition
=
43.86
Hu, Oliver Yoa-Pu; Hsiong, Cheng-Huei; Kuo, Benjamin Pei-Chung; Pao, Li-Heng
Patent: US2003/166584 A1, 2003 ; Title/Abstract Full Text Show Details
% Inhibition
=
44.09
%
Inhibitor
Cytochrome P450 3A1 [Rattus norvegicus]:Wild
Hu, Oliver Yoa-Pu; Hsiong, Cheng-Huei; Kuo, Benjamin Pei-Chung; Pao, Li-Heng
Patent: US2003/166584 A1, 2003 ; Title/Abstract Full Text Show Details
% Inhibition
=
-2.47
%
Inhibitor
cytochrome p450 2c11 [rattus norvegicus]:Wild
Hu, Oliver Yoa-Pu; Wang, Hong-Jaan; Hsiong, Cheng-Huei; Pao, Li-Heng
Patent: US2006/69042 A1, 2006 ; Title/Abstract Full Text Show Details
%
=
63.1
%
Patent: EP2241573 A2, ...
Title/Abstract Full Text Show Details
%
Inhibitor
Cytochrome P450 3A1 [Rattus norvegicus]:Wild
Patent: US2003/166584 ...
Title/Abstract Full Text Show Details
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
BIO-FDandC Co., Ltd
Patent: EP2241573 A2, 2010 ; Title/Abstract Full Text Show Details
% Inhibition
=
43.86
Hu, Oliver Yoa-Pu; Hsiong, Cheng-Huei; Kuo, Benjamin Pei-Chung; Pao, Li-Heng
Patent: US2003/166584 A1, 2003 ; Title/Abstract Full Text Show Details
5.21
Ki
=
6.13
µM
Carbonic anhydrase 6 [human]:Wild
Oeztuerk Sarikaya, Sevim Beyza; Topal, Fevzi; Sentuerk, Murat; Guelin, Ihami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4259 - 4262 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
10
%
Tyrosinase [mushroom]:Wild
Patent: EP2241573 A2, ...
Title/Abstract Full Text Show Details
µM
Carbonic anhydrase [European sea bass]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
BIO-FDandC Co., Ltd
Patent: EP2241573 A2, 2010 ; Title/Abstract Full Text Show Details
5.38
Ki
=
4.13
Oeztuerk Sarikaya, Sevim Beyza; Topal, Fevzi; Sentuerk, Murat; Guelin, Ihami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4259 - 4262 Title/Abstract Full Text View citing articles Show Details
5.65
Ki
=
2.25
µM
Carbonic anhydrase 2 [human]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Oeztuerk Sarikaya, Sevim Beyza; Topal, Fevzi; Sentuerk, Murat; Guelin, Ihami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4259 - 4262 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
-3.05
%
Inhibitor
cytochrome p450 2c11 [rattus norvegicus]:Wild
Patent: US2006/69042 A...
Title/Abstract Full Text Show Details
Patent: US2006/69042 A...
Title/Abstract Full Text Show Details
Hu, Oliver Yoa-Pu; Wang, Hong-Jaan; Hsiong, Cheng-Huei; Pao, Li-Heng
Patent: US2006/69042 A1, 2006 ; Title/Abstract Full Text Show Details
% Inhibition
=
-0.97
%
Inhibitor
cytochrome p450 2c11 [rattus norvegicus]:Wild
Hu, Oliver Yoa-Pu; Wang, Hong-Jaan; Hsiong, Cheng-Huei; Pao, Li-Heng
Patent: US2006/69042 A1, 2006 ; Title/Abstract Full Text Show Details
%
=
75.1
%
Patent: EP2241573 A2, ...
Title/Abstract Full Text Show Details
µM
Carbonic anhydrase 1 [human]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
BIO-FDandC Co., Ltd
Patent: EP2241573 A2, 2010 ; Title/Abstract Full Text Show Details
5.49
Ki
=
3.2
Oeztuerk Sarikaya, Sevim Beyza; Topal, Fevzi; Sentuerk, Murat; Guelin, Ihami; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4259 - 4262 Title/Abstract Full Text View citing articles Show Details
%
=
70.4
%
Patent: EP2241573 A2, ...
Title/Abstract Full Text Show Details
µM
HL-60 cell line
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
BIO-FDandC Co., Ltd
Patent: EP2241573 A2, 2010 ; Title/Abstract Full Text Show Details
4.67
IC50
=
21.2
Ahmed, Ejaz; Imran, Muhammad; Malik, Abdul; Ashraf, Muhammad
Archives of Pharmacal Research, 2006 , vol. 29, # 5 p. 343 - 347 Title/Abstract Full Text View citing articles Show Details
IC50
=
3.6
µg
HL-60 cell line
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Ahmed, Ejaz; Imran, Muhammad; Malik, Abdul; Ashraf, Muhammad
Archives of Pharmacal Research, 2006 , vol. 29, # 5 p. 343 - 347 Title/Abstract Full Text View citing articles Show Details
4.75
IC50
=
17.6
µM
Inhibitor
HL-60 cell line
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Ahmed, Ejaz; Imran, Muhammad; Malik, Abdul; Ashraf, Muhammad
Archives of Pharmacal Research, 2006 , vol. 29, # 5 p. 343 - 347 Title/Abstract Full Text View citing articles Show Details
4.75
IC50
=
3
µg/mL
Inhibitor
HL-60 cell line
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Ahmed, Ejaz; Imran, Muhammad; Malik, Abdul; Ashraf, Muhammad
Archives of Pharmacal Research, 2006 , vol. 29, # 5 p. 343 - 347 Title/Abstract Full Text View citing articles Show Details
5.14
IC50
=
7.3
µM
Inhibitor
SH-SY5Y
Bioorganic and Medicinal...
cell line
Title/Abstract Full Text View citing articles Show Details
Ji, Hong-Fang; Zhang, Hong-Yu; Shen, Liang
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 15 p. 4095 - 4098 Title/Abstract Full Text View citing articles Show Details
4.23
IC50
=
10
µg/mL
Inhibitor
HepG2/2.2.15 cell line
3T3-L1 cell line
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Lee, Sung-Jin; Lee, Hak-Kyo; Jung, Min-Kyung; Mar, Woongchon
Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 10 p. 2131 - 2134 Title/Abstract Full Text View citing articles Show Details
Activity
31
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Ren, Yulin; Himmeldirk, Klaus; Chen, Xiaozhuo
Journal of Medicinal Chemistry, 2006 , vol. 49, # 9 p. 2829 - 2837 Title/Abstract Full Text View citing articles Show Details
6.24
Ki
=
580
nM
Inhibitor
RNA-directed DNA polymerase:Wild
Annual reports in medici...
Title/Abstract Full Text Show Details
DNA nucleotidylexotransferase:Wild
Annual reports in medici...
Title/Abstract Full Text Show Details
DNA polymerase gamma (Gamma):Wild
Annual reports in medici...
Title/Abstract Full Text Show Details
DNA polymerase (Epsilon) [Escherichia coli]:Wild
Annual reports in medici...
Title/Abstract Full Text Show Details
DNA polymerase alpha:Wild
Annual reports in medici...
Title/Abstract Full Text Show Details
Reverse transcriptase [Human immunodeficiency virus 1]:Wild
Annual reports in medici...
Title/Abstract Full Text Show Details
DNA polymerase beta (Beta):Wild
Annual reports in medici...
Title/Abstract Full Text Show Details
Pancreatic triacylglycerol lipase [pig]:Wild
Enzymology inhibition
Molecules, 2013 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Peter J. Hylands; Louis J. Nisbet
Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details
Activity
ND
Inhibitor
Peter J. Hylands; Louis J. Nisbet
Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details
Activity
ND
Inhibitor
Peter J. Hylands; Louis J. Nisbet
Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details
Activity
ND
Inhibitor
Peter J. Hylands; Louis J. Nisbet
Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details
Activity
ND
Inhibitor
Peter J. Hylands; Louis J. Nisbet
Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details
6.24
Ki
=
580
nM
Inhibitor
Peter J. Hylands; Louis J. Nisbet
Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details
Activity
ND
Inhibitor
Peter J. Hylands; Louis J. Nisbet
Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details
1
IC50
>
300
µM
Kwon, O Jun; Bae, Jong-Sup; Lee, Ha Yeong; Hwang, Ju-Young; Lee, Eun-Woo; Ito, Hideyuki; Kim, Tae Hoon
Molecules, 2013 , vol. 18, # 9 p. 10629 - 10638 Title/Abstract Full Text View citing articles Show Details
3.53
IC50
294
µM
Hyaluronidase:Wild
Enzymology inhibition
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Enzymology inhibition
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Sgariglia, Melina A.; Soberon, Jose R.; Poveda Cabanes, Ana; Sampietro, Diego A.; Vattuone, Marta A.
Journal of Ethnopharmacology, 2013 , vol. 147, # 1 p. 63 - 73 Title/Abstract Full Text View citing articles Show Details
2.43
IC50
3.7
mM
Angiotensin-converting enzyme [rabbit]:Wild
lung
Al Shukor, Nadin; Van Camp, John; Gonzales, Gerard Bryan; Staljanssens, Dorien; Struijs, Karin; Zotti, Moises J.; Raes, Katleen; Smagghe, Guy
Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 48 p. 11832 - 11839 Title/Abstract Full Text View citing articles Show Details
2.72
% Inhibition
84
%
Angiotensin-converting enzyme [rabbit]:Wild
lung
Enzymology inhibition
10 mM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Al Shukor, Nadin; Van Camp, John; Gonzales, Gerard Bryan; Staljanssens, Dorien; Struijs, Karin; Zotti, Moises J.; Raes, Katleen; Smagghe, Guy
Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 48 p. 11832 - 11839 Title/Abstract Full Text View citing articles Show Details
2.64
% Inhibition
26
%
Angiotensin-converting enzyme [rabbit]:Wild
lung
Enzymology inhibition
0.800000 mM
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Al Shukor, Nadin; Van Camp, John; Gonzales, Gerard Bryan; Staljanssens, Dorien; Struijs, Karin; Zotti, Moises J.; Raes, Katleen; Smagghe, Guy
Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 48 p. 11832 - 11839 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
-12.2
%
aromatase [human]:Wild
cells
Enzymology inhibition
10 µM
Enzymology inhibition
0.312500 µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Park, Myeong Hyeon; Kim, In Sook; Kim, Sun-A; Na, Chun-Soo; Hong, Cheol Yi; Dong, Mi-Sook; Yoo, Hye Hyun
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1730 - 1733 Title/Abstract Full Text View citing articles Show Details
IC50
ND
Neuraminidase N2 [Influenza A virus (A/R1/5+/1957(H2N2))]:Wild
Antiviral
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Abdel-Mageed, Wael M.; Bayoumi, Soad A.H.; Chen, Caixia; Vavricka, Christopher J.; Li, Li; Malik, Ajamaluddin; Dai, Huanqin; Song, Fuhang; Wang, Luoqiang; Zhang, Jingyu; Gao, George F.; Lv, Yali; Liu, Lihong; Liu, Xueting; Sayed, Hanaa M.; Zhang, Lixin
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2236 - 2243 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
3
%
Neuraminidase N2 [Influenza A virus (A/R1/5+/1957(H2N2))]:Wild
Enzymology inhibition
100 µM
Antiviral
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Abdel-Mageed, Wael M.; Bayoumi, Soad A.H.; Chen, Caixia; Vavricka, Christopher J.; Li, Li; Malik, Ajamaluddin; Dai, Huanqin; Song, Fuhang; Wang, Luoqiang; Zhang, Jingyu; Gao, George F.; Lv, Yali; Liu, Lihong; Liu, Xueting; Sayed, Hanaa M.; Zhang, Lixin
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2236 - 2243 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
NA
Protease 3C [Coxsackievirus B3]:Wild
Enzymology inhibition
100 µM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Abdel-Mageed, Wael M.; Bayoumi, Soad A.H.; Chen, Caixia; Vavricka, Christopher J.; Li, Li; Malik, Ajamaluddin; Dai, Huanqin; Song, Fuhang; Wang, Luoqiang; Zhang, Jingyu; Gao, George F.; Lv, Yali; Liu, Lihong; Liu, Xueting; Sayed, Hanaa M.; Zhang, Lixin
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2236 - 2243 Title/Abstract Full Text View citing articles Show Details
5.25
% Inhibition
=
61.6
%
= 9 µM
scavenging
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Buemi, Maria Rosa; De Luca, Laura; Chimirri, Alba; Ferro, Stefania; Gitto, Rosaria; Alvarez-Builla, Julio; Alajarin, Ramon
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 15 p. 4575 - 4580 Title/Abstract Full Text View citing articles Show Details
6.25
% Inhibition
>
94.1
%
= 9 µM
scavenging
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Buemi, Maria Rosa; De Luca, Laura; Chimirri, Alba; Ferro, Stefania; Gitto, Rosaria; Alvarez-Builla, Julio; Alajarin, Ramon
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 15 p. 4575 - 4580 Title/Abstract Full Text View citing articles Show Details
Biodistribution
=
70.67
%
A7r5 cell line
= 30 µM
A7r5 cell line
= 30 µM
A7r5 cell line
= 30 µM
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Ou, Ting-Tsz; Lin, Ming-Cheng; Wu, Cheng-Hsun; Lin, Wea-Lung; Wang, Chau-Jong
Current Medicinal Chemistry, 2013 , vol. 20, # 31 p. 3944 - 3953 Title/Abstract Full Text View citing articles Show Details
5.8
% Inhibition
R
122.6
%
Antiproliferative
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Ou, Ting-Tsz; Lin, Ming-Cheng; Wu, Cheng-Hsun; Lin, Wea-Lung; Wang, Chau-Jong
Current Medicinal Chemistry, 2013 , vol. 20, # 31 p. 3944 - 3953 Title/Abstract Full Text View citing articles Show Details
Biodistribution
=
19.25
%
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Ou, Ting-Tsz; Lin, Ming-Cheng; Wu, Cheng-Hsun; Lin, Wea-Lung; Wang, Chau-Jong
Current Medicinal Chemistry, 2013 , vol. 20, # 31 p. 3944 - 3953 Title/Abstract Full Text View citing articles Show Details
5.11
IC50
=
7.7
µM
Inhibitor
PC12
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Liu, Yanqin; Pukala, Tara L.; Musgrave, Ian F.; Williams, Danielle M.; Dehle, Francis C.; Carver, John A.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6336 - 6340 Title/Abstract Full Text View citing articles Show Details
%
=
88
%
PC12
Cytotoxic
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Liu, Yanqin; Pukala, Tara L.; Musgrave, Ian F.; Williams, Danielle M.; Dehle, Francis C.; Carver, John A.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6336 - 6340 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
61.6
%
Gitto, Rosaria; De Luca, Laura; Ferro, Stefania; Russo, Emilio; De Sarro, Giovambattista; Chisari, Mariangela; Ciranna, Lucia; Alvarez-Builla, Julio; Alajarin, Ramon; Buemi, Maria Rosa; Chimirri, Alba
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 1040 - 1048 Title/Abstract Full Text View citing articles Show Details
% Inhibition
>
94.1
%
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Gitto, Rosaria; De Luca, Laura; Ferro, Stefania; Russo, Emilio; De Sarro, Giovambattista; Chisari, Mariangela; Ciranna, Lucia; Alvarez-Builla, Julio; Alajarin, Ramon; Buemi, Maria Rosa; Chimirri, Alba
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 1040 - 1048 Title/Abstract Full Text View citing articles Show Details
% Inhibition
>
93.9
%
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Gitto, Rosaria; De Luca, Laura; Ferro, Stefania; Russo, Emilio; De Sarro, Giovambattista; Chisari, Mariangela; Ciranna, Lucia; Alvarez-Builla, Julio; Alajarin, Ramon; Buemi, Maria Rosa; Chimirri, Alba
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 1040 - 1048 Title/Abstract Full Text View citing articles Show Details
5.27
EC50
=
5.34
µM
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Svinyarov, Ivan; Bogdanov, Milen G.
European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 198 - 206 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
10
%
Tyrosinase [mushroom]:Wild
Enzymology inhibition
100 µM
Patent: US8435548 B2, ...
Title/Abstract Full Text Show Details
10 µM
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Bio-FDandC Co., Ltd; Jung, Dai Hyun; Moh, Sang Hyun; Lee, Jung Hun; Kim, Su Jung; Kim, Hyung Sik; Seo, Hyo Hyun; Bae, Yeon Ja
Patent: US8435548 B2, 2013 ; Title/Abstract Full Text Show Details
1
% Inhibition
7.8
%
B16 melanoma 4A5 cell line
Flux release
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
14.5
%
B16 melanoma 4A5 cell line
Flux release
30 µM
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
4.13
% Inhibition
57.3
%
B16 melanoma 4A5 cell line
Flux release
100 µM
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
Activity
@
Antioxidant
Patent: WO2006/133523 ...
Title/Abstract Full Text Show Details
Antibiotic
Patent: WO2006/133523 ...
Title/Abstract Full Text Show Details
Antioxidant
Patent: WO2006/133523 ...
Title/Abstract Full Text Show Details
radical scavenging
Patent: WO2008/16593 A...
Title/Abstract Full Text Show Details
Antiaggregant
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
FLEN PHARMA N.V.; VAN DEN PLAS, Dave; DE SMET, Kris; SOLLIE, Philippe
Patent: WO2006/133523 A3, 2006 ; Title/Abstract Full Text Show Details
ENHANCED EFFECT
@
FLEN PHARMA N.V.; VAN DEN PLAS, Dave; DE SMET, Kris; SOLLIE, Philippe
Patent: WO2006/133523 A3, 2006 ; Title/Abstract Full Text Show Details
Activity
@
FLEN PHARMA N.V.; VAN DEN PLAS, Dave; DE SMET, Kris; SOLLIE, Philippe
Patent: WO2006/133523 A3, 2006 ; Title/Abstract Full Text Show Details
4.52
IC50
=
30
µM
TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Patent: WO2008/16593 A2, 2008 ; Title/Abstract Full Text Show Details
DISAGGREGATION
=
30
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
Amyloid beta A4 protein:Wild
FLUORESCENCE INHIBITION
=
14
%
Inhibitor
Amyloid beta A4 protein:Wild
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Amyloid beta A4 protein:Wild
Antiaggregant
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Inhibitor
Amyloid beta A4 protein:Wild
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Inhibitor
Amyloid beta A4 protein:Wild
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Amyloid beta A4 protein:Wild
Antiaggregant
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Inhibitor
Amyloid beta A4 protein:Wild
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Inhibitor
Amyloid beta A4 protein:Wild
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Inhibitor
Amyloid beta A4 protein:Wild
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Amyloid beta A4 protein:Wild
Antiaggregant
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Amyloid beta A4 protein:Wild
Antiaggregant
Patent: US2001/47032 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
DISAGGREGATION
=
32
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
FLUORESCENCE INHIBITION
=
57
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
FLUORESCENCE INHIBITION
=
44
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
DISAGGREGATION
=
52
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
FLUORESCENCE INHIBITION
=
34
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
FLUORESCENCE INHIBITION
=
22
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
FLUORESCENCE INHIBITION
=
45
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
DISAGGREGATION
=
17
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
DISAGGREGATION
=
22
%
Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.
Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details
2.91
MIC
=
210
µg/mL
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
0
mM
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: WO2012/119699 ...
Title/Abstract Full Text Show Details
Antioxidant
Patent: EP1893187 B1, ...
Title/Abstract Full Text Show Details
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
0
mM
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
0
mM
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
0
mM
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
0
mM
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
7
mM
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
0
mM
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
0
mM
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
ZI
=
0
mM
KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.
Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details
Activity
@
Flen Pharma N.V.
Patent: EP1893187 B1, 2008 ; Title/Abstract Full Text Show Details
Activity
@
Antioxidant
Patent: EP1893187 B1, ...
Title/Abstract Full Text Show Details
Antibiotic
Patent: EP1893187 B1, ...
Title/Abstract Full Text Show Details
%
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
Flen Pharma N.V.
Patent: EP1893187 B1, 2008 ; Title/Abstract Full Text Show Details
Activity
@
Flen Pharma N.V.
Patent: EP1893187 B1, 2008 ; Title/Abstract Full Text Show Details
%
=
8
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
11
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
99
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
82
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
3.58
IC50
=
45
µg/mL
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
3.82
IC50
=
26
µg/mL
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
96
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
91
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
17
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
90
%
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Antiinfective
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
HeLa cell line
Cytotoxic
Patent: US2009/137661 ...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
103
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
3.66
IC50
=
37
µg/mL
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
101
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
4.28
IC50
=
8.9
µg/mL
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
84
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
%
=
85
%
Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei
Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details
2.93
MIC
=
200
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.63
MIC
=
400
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.63
MIC
=
400
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.63
MIC
=
400
µg/mL
Title/Abstract Full Text Show Details
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.63
MIC
=
400
µg/mL
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Antimicrobial
Patent: US2010/34757 A...
Title/Abstract Full Text Show Details
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.63
MIC
=
400
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.33
MIC
=
800
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.63
MIC
=
400
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.03
MIC
=
1600
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.33
MIC
=
800
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.93
MIC
=
200
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.63
MIC
=
400
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.03
MIC
=
1600
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details
2.33
MIC
=
800
µg/mL
Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo
Patent: US2010/34757 A1, 2010 ;
Title/Abstract Full Text Show Details
1
% Inhibition
1.4
%
peritoneal macrophage
Flux release
3 µM
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
17.1
%
peritoneal macrophage
Flux release
100 µM
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
4.2
%
peritoneal macrophage
Flux release
30 µM
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
8
%
peritoneal macrophage
Flux release
10 µM
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
4.52
IC50
0.03
mM
Tyrosinase [banana]:Wild
Enzymology inhibition
Russian Journal of Bioor...
Title/Abstract Full Text View citing articles Show Details
Karatas, Mert Olgun; Alici, Bulent; Cetinkaya, Engin; Bilen, Cigdem; Gencer, Nahit; Arslan, Oktay
Russian Journal of Bioorganic Chemistry, 2014 , vol. 40, # 4 p. 461 - 466Bioorg. Khim. Title/Abstract Full Text View citing articles Show Details
4.71
IC50
19.4
μM
Antioxidant
Chemistry of Natural Com...
Title/Abstract Full Text View citing articles Show Details
Ochir, Sarangowa; Yuki, Takehiro; Kanazawa, Tsutomu; Nishizawa, Makoto; Yamagishi, Takashi
Chemistry of Natural Compounds, 2013 , vol. 49, # 5 p. 940 - 942Khim. Prir. Soedin., 2013 , # 5 p. 806 - 807,2 Title/Abstract Full Text View citing articles Show Details
1.73
IC50
3.2
mg/ml
Antioxidant
Phytochemistry, 2013 , ...
Title/Abstract Full Text View citing articles Show Details
Tuominen, Anu
Phytochemistry, 2013 , vol. 95, p. 408 - 420 Title/Abstract Full Text View citing articles Show Details
5.54
EC50
2.9
μM
Antioxidant
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Kim, Jina; Hong, Victor Sukbong; Lee, Jinho
Archives of Pharmacal Research, 2014 , vol. 37, # 3 p. 324 - 331 Title/Abstract Full Text View citing articles Show Details
5.37
EC50
4.3
μM
Antioxidant
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Kim, Jina; Hong, Victor Sukbong; Lee, Jinho
Archives of Pharmacal Research, 2014 , vol. 37, # 3 p. 324 - 331 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not
50 μM
Antioxidant
Archives of Pharmacal Re...
active
Title/Abstract Full Text View citing articles Show Details
Kim, Jina; Hong, Victor Sukbong; Lee, Jinho
Archives of Pharmacal Research, 2014 , vol. 37, # 3 p. 324 - 331 Title/Abstract Full Text View citing articles Show Details
5.4
% Inhibition
88.3
%
erythrocyte
30 μM
Archives of Pharmacal Re...
Title/Abstract Full Text View citing articles Show Details
Kim, Jina; Hong, Victor Sukbong; Lee, Jinho
Archives of Pharmacal Research, 2014 , vol. 37, # 3 p. 324 - 331 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
16.47
%
Inhibitor
alpha-glucosidase:Wild
500 μM
Antidiabetic
Chemical Communications,...
Title/Abstract Full Text View citing articles Show Details
Deng, Shiren; Xia, Linbo; Xiao, Hongbin
Chemical Communications, 2014 , vol. 50, # 20 p. 2582 - 2584 Title/Abstract Full Text View citing articles Show Details
2.91
IC50
1235
μM
Inhibitor
alpha-glucosidase:Wild
Antidiabetic
Chemical Communications,...
Title/Abstract Full Text View citing articles Show Details
Deng, Shiren; Xia, Linbo; Xiao, Hongbin
Chemical Communications, 2014 , vol. 50, # 20 p. 2582 - 2584 Title/Abstract Full Text View citing articles Show Details
2.84
Ki
1430
μM
Inhibitor
alpha-glucosidase:Wild
Antidiabetic
Chemical Communications,...
Title/Abstract Full Text View citing articles Show Details
Deng, Shiren; Xia, Linbo; Xiao, Hongbin
Chemical Communications, 2014 , vol. 50, # 20 p. 2582 - 2584 Title/Abstract Full Text View citing articles Show Details
5.14
EC50
7.18
μM
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Ma, Fenghua; Onoda, Toshihisa; Li, Wei; Sasaki, Tatsunori; Ma, Ling; Zhang, Qingbo; Koike, Kazuo
Natural Product Research, 2013 , vol. 27, # 23 p. 2178 - 2182 Title/Abstract Full Text View citing articles Show Details
5.37
EC50
4.24
μM
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Ma, Fenghua; Onoda, Toshihisa; Li, Wei; Sasaki, Tatsunori; Ma, Ling; Zhang, Qingbo; Koike, Kazuo
Natural Product Research, 2013 , vol. 27, # 23 p. 2178 - 2182 Title/Abstract Full Text View citing articles Show Details
4.73
IC50
3.15
μg/ml
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Ambika; Singh, Pradeep Pratap; Chauhan
Natural Product Research, 2014 , vol. 28, # 10 p. 760 - 763 Title/Abstract Full Text View citing articles Show Details
% Inhibition
96.3
%
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Damascena; Souza; Almeida; Cunha; Curvello; Lima; Santos; Dias; Paixão; Quintans Júnior; Estevam; Araujo
Natural Product Research, 2014 , vol. 28, # 10 p. 753 - 756 Title/Abstract Full Text View citing articles Show Details
4.26
IC50
9.33
μg/ml
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Damascena; Souza; Almeida; Cunha; Curvello; Lima; Santos; Dias; Paixão; Quintans Júnior; Estevam; Araujo
Natural Product Research, 2014 , vol. 28, # 10 p. 753 - 756 Title/Abstract Full Text View citing articles Show Details
Antioxidant Activity Index
4.3
no unit
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Damascena; Souza; Almeida; Cunha; Curvello; Lima; Santos; Dias; Paixão; Quintans Júnior; Estevam; Araujo
Natural Product Research, 2014 , vol. 28, # 10 p. 753 - 756 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
19
%
Caco-2
50 μg/ml
Patent: US2014/128585 ...
Title/Abstract Full Text Show Details
20 μM
Patent: US2014/163045 ...
Title/Abstract Full Text Show Details
Patent: US2014/163045 ...
Title/Abstract Full Text Show Details
0 - 60 μM
Antioxidant
Patent: US2014/163045 ...
Title/Abstract Full Text Show Details
HEK293 cell line
100 nM 1 μM
Patent: US2014/249095 ...
Title/Abstract Full Text Show Details
0 - 10 μM
Food Chemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Nagaoka Perfumery Co., Ltd.; Sugimoto, Keiichiro; Nakayama, Hiroto; Nakagawa, Kazuya; Hayashi, Syuichi
Patent: US2014/128585 A1, 2014 ; Title/Abstract Full Text Show Details
1
% Inhibition
Not active
Inhibitor
xanthine oxidase [taurine cattle]:Wild
BAYLOR COLLEGE OF MEDICINE; Chen, Changyi; Lu, Jian-Ming; Yao, Qizhi
Patent: US2014/163045 A1, 2014 ; Title/Abstract Full Text Show Details
1
% Inhibition
Not active
Inhibitor
xanthine oxidase [taurine cattle]:Wild
BAYLOR COLLEGE OF MEDICINE; Chen, Changyi; Lu, Jian-Ming; Yao, Qizhi
Patent: US2014/163045 A1, 2014 ; Title/Abstract Full Text Show Details
Tested
Not published
BAYLOR COLLEGE OF MEDICINE; Chen, Changyi; Lu, Jian-Ming; Yao, Qizhi
Patent: US2014/163045 A1, 2014 ; Title/Abstract Full Text Show Details
%
90 - 95
%
Inhibitor
ATXN3/Q75:Wild
National Normal University; LEE-CHEN, Guey-Jen; CHEN, Chiung-Mei
Patent: US2014/249095 A1, 2014 ; Title/Abstract Full Text Show Details
4.95
IC50
11.3
μM
Salazar, Ricardo; Arambula-Villa, Geronimo; Hidalgo, Francisco J.; Zamora, Rosario
Food Chemistry, 2014 , vol. 151, p. 480 - 486 Title/Abstract Full Text View citing articles Show Details
5.09
IC50
8.18
μM
0 - 10 μM
Food Chemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Salazar, Ricardo; Arambula-Villa, Geronimo; Hidalgo, Francisco J.; Zamora, Rosario
Food Chemistry, 2014 , vol. 151, p. 480 - 486 Title/Abstract Full Text View citing articles Show Details
5.13
IC50
7.49
μM
0 - 10 μM
Food Chemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Salazar, Ricardo; Arambula-Villa, Geronimo; Hidalgo, Francisco J.; Zamora, Rosario
Food Chemistry, 2014 , vol. 151, p. 480 - 486 Title/Abstract Full Text View citing articles Show Details
4.52
% Inhibition
35.59
%
Inhibitor
Cytochrome P450 2E1:Wild
16.5 μM
Patent: US2014/38921 A...
Title/Abstract Full Text Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien
Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details
4.15
% Inhibition
48.24
%
Inhibitor
Cytochrome P450 2E1:Wild
66 μM
Patent: US2014/38921 A...
Title/Abstract Full Text Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien
Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details
1
% Inhibition
-20.2
%
Inhibitor
Amidase [Mus musculus]:Wild
liver
100 μM
Patent: US2014/38921 A...
Title/Abstract Full Text Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien
Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details
1
% Inhibition
12
%
Inhibitor
Amidase [Mus musculus]:Wild
liver
1 μM
Patent: US2014/38921 A...
Title/Abstract Full Text Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien
Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details
1
% Inhibition
20
%
Inhibitor
Amidase [Mus musculus]:Wild
liver
10 μM
Patent: US2014/38921 A...
Title/Abstract Full Text Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien
Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details
1
% Inhibition
10.5
%
Inhibitor
Cytochrome P450 2E1 [human]:Wild
16.5 μM
Patent: US2014/38921 A...
Title/Abstract Full Text Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien
Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details
1
% Inhibition
18.79
%
Inhibitor
Cytochrome P450 2E1 [human]:Wild
33 μM
Patent: US2014/38921 A...
Title/Abstract Full Text Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien
Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details
3.77
% Inhibition
27.96
%
Inhibitor
Cytochrome P450 2E1 [human]:Wild
66 μM
Patent: US2014/38921 A...
Title/Abstract Full Text Show Details
NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien
Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details
pX
Parameter
Value (qual)
Value (quant)
Unit
%
=
4.3
%
Action on Target
Target
Tissue/Organ
Cell
Bioassay
HL-60 cell line
Dose
Effect
Reference (expand all/collapse all)
Cytotoxic
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Anti-RSV
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Kakumu, Akinori; Ninomiya, Masayuki; Efdi, Mai; Adfa, Morina; Hayashi, Masahiro; Tanaka, Kaori; Koketsu, Mamoru
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 17 p. 4286 - 4290 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Antiviral
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Antiviral
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Anti-Influenza
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Anti-Influenza
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Antiviral
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Anti-Herpes
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Anti-Influenza
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Antiviral
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Antiviral
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Antiviral
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Antiviral
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Antiviral
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
50
μM
CCRF-CEM cell line
Anti-HIV
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
50
μM
CCRF-CEM cell line
Anti-HIV
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
2.33
IC50
0.8
μg/μl
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Dah-Nouvlessounon, Durand; Adoukonou-Sagbadja, Hubert; Diarrassouba, Nafan; Sina, Haziz; Noumavo, Pacôme A.; Baba-Moussa, Farid; Adjanohoun, Adolphe; Gbenou, Joachim D.; Baba-Moussa, Lamine
International Journal of Pharmacy and Pharmaceutical Sciences, 2015 , vol. 7, # 6 p. 102 - 109 Title/Abstract Full Text View citing articles Show Details
3.89
% Inhibition
70
%
300 μM
Antioxidant
Food Chemistry, 2015 , ...
Title/Abstract Full Text Show Details
Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.
Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details
5.33
EC50
4.7
μM
Antioxidant
Food Chemistry, 2015 , ...
Title/Abstract Full Text Show Details
Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.
Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details
5.38
EC50
4.2
μM
Antioxidant
Food Chemistry, 2015 , ...
Title/Abstract Full Text Show Details
Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.
Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details
5.46
EC50
3.5
μM
Antioxidant
Food Chemistry, 2015 , ...
Title/Abstract Full Text Show Details
Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.
Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details
5.42
EC50
3.8
μM
Antioxidant
Food Chemistry, 2015 , ...
Title/Abstract Full Text Show Details
Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.
Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details
Time
60
min
Antioxidant
Food Chemistry, 2015 , ...
Title/Abstract Full Text Show Details
Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.
Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details
7.22
EC50
0.06
μM
Antioxidant
Food Chemistry, 2015 , ...
Title/Abstract Full Text Show Details
Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.
Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details
3.2
MIC
625
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
3.33
MIC
469
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
5000
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
5000
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
5000
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
5000
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
5000
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
5000
μM
Antibiotic :
ChemMedChem, 2015 , vol...
Enhancer
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
5000
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
5000
μM
Antibiotic : Enhancer
ChemMedChem, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.
ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details
IC50
Not Published
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Rakesh; Manukumar; Gowda, D. Channe
Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 5 p. 998 - 1003 Title/Abstract Full Text View citing articles Show Details
IC50
Not Published
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Rakesh; Manukumar; Gowda, D. Channe
Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 5 p. 998 - 1003 Title/Abstract Full Text View citing articles Show Details
4.42
IC50
6.5
μg/ml
Antioxidant
PLoS ONE, 2014 , vol. 9...
Title/Abstract Full Text View citing articles Show Details
Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan
PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details
2.77
IC50
0.29
mg/ml
Antioxidant
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Stankov-Jovanović; Ilić; Mitić; Mihajilov-Krstev; Simonović; Nikolić Mandić; Tabet; Cole
Journal of Pharmaceutical and Biomedical Analysis, 2015 , vol. 111, p. 78 - 90 Title/Abstract Full Text View citing articles Show Details
Trolox Equivalents
3.02
μg/ml
Antioxidant
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Stankov-Jovanović; Ilić; Mitić; Mihajilov-Krstev; Simonović; Nikolić Mandić; Tabet; Cole
Journal of Pharmaceutical and Biomedical Analysis, 2015 , vol. 111, p. 78 - 90 Title/Abstract Full Text View citing articles Show Details
Concentration
70.58
μg/mg
Antioxidant
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Stankov-Jovanović; Ilić; Mitić; Mihajilov-Krstev; Simonović; Nikolić Mandić; Tabet; Cole
Journal of Pharmaceutical and Biomedical Analysis, 2015 , vol. 111, p. 78 - 90 Title/Abstract Full Text View citing articles Show Details
% increase
Active
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Uy; Licuanan; Angeles; Bote; Macauyag; Hernandez; Jacinto; Guzman-Genuino
International Journal of Cancer Research, 2015 , vol. 11, # 2 p. 80 - 92 Title/Abstract Full Text View citing articles Show Details
4.79
IC50
=
2.79
µg/mL
scavenging
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Kim, Ki Hyun; Park, Yong Joo; Chung, Kyu Hyuck; Yip, M. L. Richard; Clardy, Jon; Senger, Donald; Cao, Shugeng
Journal of Natural Products, 2015 , vol. 78, # 2 p. 320 - 324 Title/Abstract Full Text View citing articles Show Details
Trolox Equivalents
18.6
no unit
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Prez-Areales, F. Javier; Di Pietro, Ornella; Espargar, Alba; Vallverd-Queralt, Anna; Galdeano, Carles; Ragusa, Ilaria M.; Viayna, Elisabet; Guillou, Catherine; Clos, M. Victria; Prez, Beln; Sabat, Raimon; LamuelaRavents, Rosa M.; Luque, F. Javier; Muoz-Torrero, Diego
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 19 p. 5298 - 5307 Title/Abstract Full Text View citing articles Show Details
Trolox Equivalents
10.3
no unit
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Prez-Areales, F. Javier; Di Pietro, Ornella; Espargar, Alba; Vallverd-Queralt, Anna; Galdeano, Carles; Ragusa, Ilaria M.; Viayna, Elisabet; Guillou, Catherine; Clos, M. Victria; Prez, Beln; Sabat, Raimon; LamuelaRavents, Rosa M.; Luque, F. Javier; Muoz-Torrero, Diego
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 19 p. 5298 - 5307 Title/Abstract Full Text View citing articles Show Details
3.42
IC50
382.4
μM
Inhibitor
Serine protease NS3 [Hepatitis C virus]:Wild
Fitoterapia, 2014 , vol...
Title/Abstract Full Text Show Details
20 μg/ml
Antioxidant
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Ajala, Olusegun S.; Jukov, Azzaya; Ma, Chao-Mei
Fitoterapia, 2014 , vol. 99, p. 117 - 123 Title/Abstract Full Text Show Details
5.21
% Inhibition
96.7
%
Sevindik, Handan G.; Güvenalp, Zühal; Yerdelen, Kadir Ö.; Yuca, Hafize; Demirezer, L. Ömür
Medicinal Chemistry Research, 2015 , vol. 24, # 11 p. 3794 - 3802 Title/Abstract Full Text View citing articles Show Details
5.15
IC50
0.007
mM
Antioxidant
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Sevindik, Handan G.; Güvenalp, Zühal; Yerdelen, Kadir Ö.; Yuca, Hafize; Demirezer, L. Ömür
Medicinal Chemistry Research, 2015 , vol. 24, # 11 p. 3794 - 3802 Title/Abstract Full Text View citing articles Show Details
5.29
IC50
0.876
μg/ml
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Ghate, Nikhil Baban; Chaudhuri, Dipankar; Das, Abhishek; Panja, Sourav; Mandal, Nripendranath
PLoS ONE, 2015 , vol. 10, # 5 art. no. E0128221 Title/Abstract Full Text View citing articles Show Details
1
IC50
100
μmol/ml
25 300 μmol/ml
Antioxidant
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Rakesh; Manukumar; Gowda, D. Channe
Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 5 p. 998 - 1003 Title/Abstract Full Text View citing articles Show Details
1.22
IC50
60
μmol/ml
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Rakesh; Manukumar; Gowda, D. Channe
Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 5 p. 998 - 1003 Title/Abstract Full Text View citing articles Show Details
3.83
% Increase
Active
HUVEC cell line
25 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
1
% Increase
Not active
HUVEC cell line
25 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
3.83
% Increase
Active
HUVEC cell line
25 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
4.13
% Increase
Active
HUVEC cell line
12.5 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
3.53
% Increase
Active
HUVEC cell line
50 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
3.23
% Increase
Active
HUVEC cell line
100 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
Fold-increase
1.4
no unit
HUVEC cell line
25 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
1
% Increase
Not active
HUVEC cell line
50 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
4.13
Amount increase
Active
HUVEC cell line
12.5 μg/ml 50 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
4.13
Amount increase
Active
HUVEC cell line
12.5 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
3.66
IC50
37.38
μg/ml
Inhibitor
Angiotensinconverting enzyme:Wild
16.5132 μg/ml
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
Amount
75.6 83.6
%
100 μM
Antioxidant
Journal of Inflammation ...
Title/Abstract Full Text View citing articles Show Details
Marimoutou, Méry; Le Sage, Fanny; Smadja, Jacqueline; D'Hellencourt, Christian Lefebvre; Gonthier, Marie-Paule; Da Silva, Christine Robert
Journal of Inflammation (United Kingdom), 2015 , vol. 12, # 1 art. no. 055 Title/Abstract Full Text View citing articles Show Details
4.14
IC50
12.2
μg/ml
Antioxidant
Bangladesh Journal of Ph...
Title/Abstract Full Text View citing articles Show Details
Mbhele, Nobuhle; Balogun, Fatai O.; Kazeem, Mutiu I.; Ashafa, Tom
Bangladesh Journal of Pharmacology, 2015 , vol. 10, # 1 p. 214 - 221 Title/Abstract Full Text View citing articles Show Details
4.08
IC50
14
μg/ml
Antioxidant
Bangladesh Journal of Ph...
Title/Abstract Full Text View citing articles Show Details
Mbhele, Nobuhle; Balogun, Fatai O.; Kazeem, Mutiu I.; Ashafa, Tom
Bangladesh Journal of Pharmacology, 2015 , vol. 10, # 1 p. 214 - 221 Title/Abstract Full Text View citing articles Show Details
5.05
IC50
1.5
μg/ml
Antioxidant
Bangladesh Journal of Ph...
Title/Abstract Full Text View citing articles Show Details
Mbhele, Nobuhle; Balogun, Fatai O.; Kazeem, Mutiu I.; Ashafa, Tom
Bangladesh Journal of Pharmacology, 2015 , vol. 10, # 1 p. 214 - 221 Title/Abstract Full Text View citing articles Show Details
% Inhibition
91.93
%
Antioxidant
Oriental Pharmacy and Ex...
Title/Abstract Full Text View citing articles Show Details
Boudaoud-Ouahmed, Hania; Tiab, Sid-Ali; Saidani, Nabil; Gherrou, Mehdi; Ziane, Keltoum; Atmani, Djebbar
Oriental Pharmacy and Experimental Medicine, 2015 , vol. 15, # 4 p. 353 - 363 Title/Abstract Full Text View citing articles Show Details
% Inhibition
63.86
%
Inhibitor
Lysine-specific demethylase 5B:Wild
Sf21 cell line
Patent: US2015/272939 ...
Title/Abstract Full Text Show Details
Inhibitor
xanthine oxidase:Wild
Antigout agent
Patent: WO2015/191034 ...
Title/Abstract Full Text Show Details
20 μM
Antigout agent
Patent: WO2015/191034 ...
Title/Abstract Full Text Show Details
Yale University; Yan, Qin; Sayegh, Joyce
Patent: US2015/272939 A1, 2015 ; Title/Abstract Full Text Show Details
1
% Inhibition50
Not active
BAYLOR COLLEGE OF MEDICINE; CHEN, Changyi; LU, Jian-Ming; YAO, Qizhi
Patent: WO2015/191034 A1, 2015 ; Title/Abstract Full Text Show Details
1
% Inhibition50
Not active
Inhibitor
xanthine oxidase:Wild
BAYLOR COLLEGE OF MEDICINE; CHEN, Changyi; LU, Jian-Ming; YAO, Qizhi
Patent: WO2015/191034 A1, 2015 ; Title/Abstract Full Text Show Details
3.53
IC50
0.05
mg/ml
Antioxidant
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2015 , vol. 72, # 6 p. 1201 - 1215 Title/Abstract Full Text View citing articles Show Details
2.93
IC50
0.2
mg/ml
Antiglycolytic
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2015 , vol. 72, # 6 p. 1201 - 1215 Title/Abstract Full Text View citing articles Show Details
4.8
IC50
=
15.66
µM
scavenging
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Liu, Jia-Bao; Ding, Ya-Si; Zhang, Ying; Chen, Jia-Bao; Cui, Bao-Song; Bai, Jin-Ye; Lin, Ming-Bao; Hou, Qi; Zhang, Pei-Cheng; Li, Shuai
Journal of Natural Products, 2015 , vol. 78, # 5 p. 1015 - 1025 Title/Abstract Full Text View citing articles Show Details
5.14
IC50
=
7.23
µM
scavenging
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Liu, Jia-Bao; Ding, Ya-Si; Zhang, Ying; Chen, Jia-Bao; Cui, Bao-Song; Bai, Jin-Ye; Lin, Ming-Bao; Hou, Qi; Zhang, Pei-Cheng; Li, Shuai
Journal of Natural Products, 2015 , vol. 78, # 5 p. 1015 - 1025 Title/Abstract Full Text View citing articles Show Details
5
EC50
10 - 12
µM
Antioxidant
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Jiang, Wen-Jun; Ishiuchi, Kan'Ichiro; Furukawa, Megumi; Takamiya, Tomoko; Kitanaka, Susumu; Iijima, Hiroshi
Bioorganic and Medicinal Chemistry, 2015 , vol. 23, # 21 p. 6922 - 6929 Title/Abstract Full Text View citing articles Show Details
% reduction
-59.3
%
THP-1 cell line
0.3 μg/ml
European Journal of Nutr...
Title/Abstract Full Text View citing articles Show Details
Del Bo, Cristian; Cao, Yi; Roursgaard, Martin; Riso, Patrizia; Porrini, Marisa; Loft, Steffen; Moller, Peter
European Journal of Nutrition, 2016 , vol. 55, # 1 p. 171 - 182 Title/Abstract Full Text View citing articles Show Details
6.54
% reduction
Active
THP-1 cell line
0.29 58.8 μM
European Journal of Nutr...
Title/Abstract Full Text View citing articles Show Details
Del Bo, Cristian; Cao, Yi; Roursgaard, Martin; Riso, Patrizia; Porrini, Marisa; Loft, Steffen; Moller, Peter
European Journal of Nutrition, 2016 , vol. 55, # 1 p. 171 - 182 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
103.1
%
Inhibitor
Isocitrate dehydrogenase [NADP] [human]:Mutated
inhibitory activity
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kim, Hyo-Joon; Fei, Xiang; Cho, Seok-Cheol; Choi, Bu Young; Ahn, Hee-Chul; Lee, Kyeong; Seo, Seung-Yong; Keum, Young-Sam
Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 23 p. 5625 - 5631 Title/Abstract Full Text View citing articles Show Details
% Inhibition
=
97.4
%
Inhibitor
Isocitrate dehydrogenase [NADP] [human]:Wild
inhibitory activity
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kim, Hyo-Joon; Fei, Xiang; Cho, Seok-Cheol; Choi, Bu Young; Ahn, Hee-Chul; Lee, Kyeong; Seo, Seung-Yong; Keum, Young-Sam
Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 23 p. 5625 - 5631 Title/Abstract Full Text View citing articles Show Details
3.48
IC50
332.6
μM
Inhibitor
Pyruvate kinase PKM [human]:Wild
Journal of Enzyme Inhibi...
Title/Abstract Full Text View citing articles Show Details
Aslan, Erdem; Guler, Caglar; Adem, Sevki
Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 , vol. 31, # 2 p. 314 - 317 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Active
Inhibitor
Tyrosinase [mushroom]:Wild
Patent: WO2016/14529 A...
Title/Abstract Full Text Show Details
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
WISYS TECHNOLOGY FOUNDATION, INC.; HUANG, Cheng-Chen; MONTE, Aaron P.
Patent: WO2016/14529 A1, 2016 ; Title/Abstract Full Text Show Details
3.04
IC50
156.29
μg/ml
Prakasia, Pressy P.; Nair, Ashalatha S.
International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details
2.95
% Inhibition
56.53
%
250 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Prakasia, Pressy P.; Nair, Ashalatha S.
International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details
3.1
% Inhibition
47.82
%
125 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Prakasia, Pressy P.; Nair, Ashalatha S.
International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details
2.48
% Inhibition
78.26
%
2000 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Prakasia, Pressy P.; Nair, Ashalatha S.
International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details
2.72
% Inhibition
60.86
%
500 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Prakasia, Pressy P.; Nair, Ashalatha S.
International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details
2.5
% Inhibition
65.22
%
1000 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Prakasia, Pressy P.; Nair, Ashalatha S.
International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details
4
% Inhibition
Active
Inhibitor
2-oxoglutarate and iron-dependent oxygenase domaincontaining protein 1 (OGFOD1) [human]:Wild
100 μM
Patent: US9228224 B2, ...
Title/Abstract Full Text Show Details
ISIS INNOVATION LIMITED; Schofield, Christopher Joseph; Wolf, Alexander; Ge, Wei; Thalhammer, Armin; Loenarz, Christoph; Ratcliffe, Peter John; Cockman, Matthew Edward
Patent: US9228224 B2, 2016 ; Title/Abstract Full Text Show Details
% Inhibition
77.2
%
1 - 20 μM
Atherosclerosis, 2016 , ...
Title/Abstract Full Text View citing articles Show Details
Jun, Moon Young; Karki, Rajendra; Paudel, Keshav Raj; Sharma, Bhesh Raj; Adhikari, Deepak; Kim, Dong-Wook
Atherosclerosis, 2016 , vol. 248, p. 179 - 189
Title/Abstract Full Text View citing articles Show Details
2.36
IC50
734.81
μg/ml
PLoS ONE, 2016 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Saha, Manas Ranjan; Dey, Priyankar; Begum, Sainiara; De, Bratati; Chaudhuri, Tapas Kr.; De Sarker, Dilip; Das, Abhaya Prasad; Sen, Arnab
PLoS ONE, 2016 , vol. 11, # 3 art. no. E0150574 Title/Abstract Full Text View citing articles Show Details
Amount
95.2
%
2 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
52.2
%
14 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
81.9
%
6 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
61.9
%
10 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
3.6
%
2 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
12.2
%
6 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
28.6
%
14 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
23.4
%
10 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
1
%
2 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
14.6
%
10 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
6.1
%
6 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
18.8
%
14 μM
Dislipidemia
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% Increase
Not active
blood
erythrocyte
290 μM
Free Radical Research, 2...
Title/Abstract Full Text View citing articles Show Details
Tedesco, Idolo; Moccia, Stefania; Volpe, Silvestro; Alfieri, Giovanna; Strollo, Daniela; Bilotto, Stefania; Spagnuolo, Carmela; Di Renzo, Massimo; Aquino, Rita P.; Russo, Gian Luigi
Free Radical Research, 2016 , vol. 50, # 5 p. 557 - 569 Title/Abstract Full Text View citing articles Show Details
4.53
% Inhibition
Active
5 - 200 μg/ml
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Chaudhuri, Dipankar; Ghate, Nikhil Baban; Panja, Sourav; Das, Abhishek; Mandal, Nripendranath
PLoS ONE, 2015 , vol. 10, # 12 art. no. E0144280 Title/Abstract Full Text View citing articles Show Details
4.53
% Inhibition
Active
5 - 120 μg/ml
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Chaudhuri, Dipankar; Ghate, Nikhil Baban; Panja, Sourav; Das, Abhishek; Mandal, Nripendranath
PLoS ONE, 2015 , vol. 10, # 12 art. no. E0144280 Title/Abstract Full Text View citing articles Show Details
2.29
IC50
0.876
mg/ml
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Chaudhuri, Dipankar; Ghate, Nikhil Baban; Panja, Sourav; Das, Abhishek; Mandal, Nripendranath
PLoS ONE, 2015 , vol. 10, # 12 art. no. E0144280 Title/Abstract Full Text View citing articles Show Details
Amount
93.154
%
Antiradical
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Politi, Flávio A.S.; Queiroz-Fernandes, Geisiany M.; Rodrigues, Edvânio R.; Freitas, Jolindo A.; Pietro, Rosemeire C.L.R.
Microbial Pathogenesis, 2016 , vol. 95, p. 15 - 20 Title/Abstract Full Text View citing articles Show Details
3.81
IC50
155.21
μM
10 1000 μM
Antioxidant
Toxicology in Vitro, 201...
Title/Abstract Full Text View citing articles Show Details
Paudel, Keshav Raj; Karki, Rajendra; Kim, Dong-Wook
Toxicology in Vitro, 2016 , vol. 34, p. 16 - 25 Title/Abstract Full Text View citing articles Show Details
% decrease50
High
10 100 μM
Antioxidant
Toxicology in Vitro, 201...
Title/Abstract Full Text View citing articles Show Details
Paudel, Keshav Raj; Karki, Rajendra; Kim, Dong-Wook
Toxicology in Vitro, 2016 , vol. 34, p. 16 - 25 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Inhibitor
xanthine oxidase [taurine cattle]:Wild
Patent: US2015/353471 ...
Title/Abstract Full Text Show Details
Patent: US2015/353471 ...
Title/Abstract Full Text Show Details
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Baylor College of Medicine; Chen, Changyi; YAO, Qizhi; LU, Jian-Ming
Patent: US2015/353471 A1, 2015 ; Title/Abstract Full Text Show Details
% scavenging
High
Baylor College of Medicine; Chen, Changyi; YAO, Qizhi; LU, Jian-Ming
Patent: US2015/353471 A1, 2015 ; Title/Abstract Full Text Show Details
5.34
IC50
0.77
μg/ml
Fakhrudin; Khairunnisa; Azzahra; Ajiningtyas
International Journal of Pharmaceutical and Clinical Research, 2016 , vol. 8, # 5 p. 352 - 356 Title/Abstract Full Text View citing articles Show Details
4.11
IC50
78.11
μM
rbl-2h3
Antiallergic
Journal of Natural Medic...
Title/Abstract Full Text View citing articles Show Details
Shi, Yan-Hong; Zhu, Shu; Tamura, Takayuki; Kadowaki, Makoto; Wang, Zhengtao; Yoshimatsu, Kayo; Komatsu, Katsuko
Journal of Natural Medicines, 2016 , vol. 70, # 2 p. 234 - 240 Title/Abstract Full Text View citing articles Show Details
4.52
IC50
30.4
μM
10 1000 μM
Antioxidant
Carbohydrate Research, 2...
Title/Abstract Full Text View citing articles Show Details
Shaikh, Qurat-Ul-Ain; Yang, Meiting; Memon, Khadim Hussain; Lateef, Mehreen; Na, Du; Wan, Shengbiao; Eric, Deslandes; Zhang, Lijuan; Jiang, Tao
Carbohydrate Research, 2016 , vol. 430, p. 72 - 81 Title/Abstract Full Text View citing articles Show Details
5.15
EC50
7
μM
51000 μM
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia
European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details
Trolox equivalent
1.18
no unit
1 - 30 μM
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia
European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details
6.15
IC50
0.7
μM
0.1 μM - 40 mM
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia
European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details
4.62
IC50
4.12
μg/ml
RAW 264.7
3.125 -
Drug Design, Development...
cell line
100 μg/ml
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng
Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details
4.09
IC50
13.92
μg/ml
peripheral blood mononuclear cell
peripheral blood mononuclear cell
3.125 100 μg/ml
3.125 100 μg/ml
2 mg/ml
Antioxidant
Drug Design, Development...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng
Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details
3.68
IC50
35.28
μg/ml
Drug Design, Development...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng
Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details
% Scavenging
93.13
%
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Siddiqui, Maqsood A.; Rasheed, Saima; Saquib, Quaiser; Al-Khedhairy, Abdulaziz A.; Al-Said, Mansour S.; Musarrat, Javed; Choudhary, Muhammad Iqbal
BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 276 Title/Abstract Full Text View citing articles Show Details
4.63
IC50
0.004
mg/ml
Antioxidant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Siddiqui, Maqsood A.; Rasheed, Saima; Saquib, Quaiser; Al-Khedhairy, Abdulaziz A.; Al-Said, Mansour S.; Musarrat, Javed; Choudhary, Muhammad Iqbal
BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 276 Title/Abstract Full Text View citing articles Show Details
% reduction
High
<= 250 μg/ml
Antioxidant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Afsar, Tayyaba; Razak, Suhail; Khan, Muhammad Rashid; Mawash, Saadia; Almajwal, Ali; Shabir, Maria; Haq, Ihsan Ul
BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 258 Title/Abstract Full Text View citing articles Show Details
3.73
EC50
32
μg/ml
25-250 μg/ml
Antioxidant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Afsar, Tayyaba; Razak, Suhail; Khan, Muhammad Rashid; Mawash, Saadia; Almajwal, Ali; Shabir, Maria; Haq, Ihsan Ul
BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 258 Title/Abstract Full Text View citing articles Show Details
3.77
EC50
29
μg/ml
<= 100 μM
Antioxidant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Afsar, Tayyaba; Razak, Suhail; Khan, Muhammad Rashid; Mawash, Saadia; Almajwal, Ali; Shabir, Maria; Haq, Ihsan Ul
BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 258 Title/Abstract Full Text View citing articles Show Details
5.3
EC50
5-6
μM
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana
PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details
Second-order rate constant (k2)
8.3
μM-1*s1
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana
PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details
3.68
IC50
210 340
μM
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana
PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details
Number
85.1
no unit
peripheral blood mononuclear cell
peripheral blood mononuclear cell
31.25 μM
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana
PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details
Number
76.9
no unit
62.5 μM
Antioxidant
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana
PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details
4.6
IC50
4.3
μg/ml
Antioxidant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Padumadasa, Chayanika; Dharmadana, Durga; Abeysekera, Ajit; Thammitiyagodage, Mayuri
BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 345 Title/Abstract Full Text View citing articles Show Details
2.93
IC50
0.2
mg/ml
Inhibitor
Hemoglobin:Wild
30 240 μg/ml
Antidiabetic
30 μg/ml
Antidiabetic
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
% Inhibition50
High
Inhibitor
Hemoglobin:Wild
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
3.45
% Inhibition
Active
Inhibitor
alpha-glucosidase [Saccharomyces cerevisiae]:Wild
60 μg/ml
Antidiabetic
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
3.53
IC50
0.05
mg/ml
30 240 μg/ml
Antioxidant
30 μg/ml
Antioxidant
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
% scavenging
High
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
% scavenging
High
60 μg/ml
Antioxidant
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
% scavenging
High
120 μg/ml
Antioxidant
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
% scavenging
High
240 μg/ml
Antioxidant
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
% Inhibition50
High
Inhibitor
Hemoglobin:Wild
60 μg/ml
Antidiabetic
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
% Inhibition50
High
Inhibitor
Hemoglobin:Wild
120 μg/ml
Antidiabetic
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
% Inhibition50
High
Inhibitor
Hemoglobin:Wild
240 μg/ml
Antidiabetic
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
3.15
% Inhibition
Active
Inhibitor
alpha-glucosidase [Saccharomyces cerevisiae]:Wild
120 μg/ml
Antidiabetic
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
2.85
% Inhibition
Active
Inhibitor
alpha-glucosidase [Saccharomyces cerevisiae]:Wild
240 μg/ml
Antidiabetic
Acta Poloniae Pharmaceut...
Title/Abstract Full Text View citing articles Show Details
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details
4
% Inhibition
Active
100 200 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
% Inhibition
High
MDCK cell line
1 - 100 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
% Inhibition
High
MDCK cell line
1 - 100 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
% Reduction
59 - 93
%
MDCK cell line
1 - 400 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
% Reduction
59 - 93
%
MDCK cell line
1 - 400 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
% Reduction
59 - 93
%
MDCK cell line
1-400 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
% Reduction
59 - 93
%
MDCK cell line
1- 400 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
5.41
% Inhibition
Active
3.9 1000 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
5.41
% Inhibition
Active
3.9 1000 μM
Anti-Influenza
Viruses, 2016 , vol. 8,...
Title/Abstract Full Text View citing articles Show Details
Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun
Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details
3.2
MIC
625
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
Antistaphylococcal
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
1
MIC
>
5000
μM
Antibiotic
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Antibiotic
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Antibiotic
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Antibiotic
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Antibiotic
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Antistaphylococcal
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Antibiotic
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Anti-MRSA
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Anti-MRSA
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Anti-MRSA
Patent: WO2016/154051 ...
Title/Abstract Full Text Show Details
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
1
MIC
>
5000
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
1
MIC
>
5000
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
3.33
MIC
469
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
1
MIC
>
5000
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
1
MIC
>
5000
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
3.2
MIC
625
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
1
MIC
>
5000
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
1
MIC
>
5000
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
1
MIC
>
5000
μM
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron
Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details
6
% Decrease
Active
Caco-2 cell line
1 μM
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
5
% Decrease
Active
Caco-2 cell line
10 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
6
% Decrease
Active
Caco-2 cell line
1 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
5
% Decrease
Active
Caco-2 cell line
10 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
7
% Decrease
Active
Caco-2 cell line
0.1 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
2
nmol/mg protein
Caco-2 cell line
10 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
1.8
nmol/mg protein
Caco-2 cell line
0.1 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
2
nmol/mg protein
Caco-2 cell line
1 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
241
ng/mg protein
Caco-2 cell line
0.1 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
236.9
ng/mg protein
Caco-2 cell line
10 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
248.7
ng/mg protein
Caco-2 cell line
1 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
108.6
mU/mg protein
Caco-2 cell line
1 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
102.6
mU/mg protein
Caco-2 cell line
10 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
101.8
mU/mg protein
Caco-2 cell line
0.1 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
2.9
mU/mg protein
Caco-2 cell line
0.1 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
2.5
mU/mg protein
Caco-2 cell line
10 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
Amount
2.6
mU/mg protein
Caco-2 cell line
1 μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
4900
μM
Inhibitor
Thymidylate synthase ThyX [human]:Wild
10 100 μM
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Borsari, Chiara; Lucian, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-Da-silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Iacono, Lucia Dello; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jiménez-Antón, María D.; Corral, María J.; Alunda, José Ma; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola
Journal of Medicinal Chemistry, 2016 , vol. 59, # 16 p. 7598 - 7616 Title/Abstract Full Text View citing articles Show Details
4.03
IC50
94.3
μM
Inhibitor
dihydrofolate reductase [human]:Wild
10 100 μM
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Borsari, Chiara; Lucian, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-Da-silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Iacono, Lucia Dello; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jiménez-Antón, María D.; Corral, María J.; Alunda, José Ma; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola
Journal of Medicinal Chemistry, 2016 , vol. 59, # 16 p. 7598 - 7616
Title/Abstract Full Text View citing articles Show Details
4.15
IC50
70.6
μM
Inhibitor
Pteridine reductase 1 [Trypanosoma brucei]:Wild
10 100 μM
Antitrypanosomal
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Borsari, Chiara; Lucian, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-Da-silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Iacono, Lucia Dello; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jiménez-Antón, María D.; Corral, María J.; Alunda, José Ma; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola
Journal of Medicinal Chemistry, 2016 , vol. 59, # 16 p. 7598 - 7616 Title/Abstract Full Text View citing articles Show Details
5.4
IC50
4
μM
10 100 μM
Antitrypanosomal
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Borsari, Chiara; Lucian, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-Da-silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Iacono, Lucia Dello; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jiménez-Antón, María D.; Corral, María J.; Alunda, José Ma; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola
Journal of Medicinal Chemistry, 2016 , vol. 59, # 16 p. 7598 - 7616 Title/Abstract Full Text View citing articles Show Details
4.22
% Inhibition
71
%
Inhibitor
UDP-glucose 6dehydrogenase:Wild
25 μg/ml
Patent: US2016/310528 ...
Title/Abstract Full Text Show Details
Tyrosinase:Wild
B16
Patent: EP2467134 B1, ...
Title/Abstract Full Text Show Details
NUtech Ventures; Simpson, Melanie A.; Barycki, Joseph
Patent: US2016/310528 A1, 2016 ; Title/Abstract Full Text Show Details
% Inhibition
Active
Inhibitor
Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola
Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details
%
89.2
%
Inhibitor
Tyrosinase:Wild
B16
0.05 mg/ml
Patent: EP2467134 B1, ...
Title/Abstract Full Text Show Details
Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola
Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details
%
83.4
%
Inhibitor
Tyrosinase:Wild
B16
0.075 mg/ml
Patent: EP2467134 B1, ...
Title/Abstract Full Text Show Details
Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola
Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details
%
92.5
%
Inhibitor
Tyrosinase:Wild
B16
0.025 mg/ml
Patent: EP2467134 B1, ...
Title/Abstract Full Text Show Details
Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola
Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details
Concentration
22.2949
μg/ml
Inhibitor
Tyrosinase:Wild
epidermis cell
25 μg/ml
Patent: EP2467134 B1, ...
Title/Abstract Full Text Show Details
Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola
Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details
%
84.0503
%
Inhibitor
Tyrosinase:Wild
epidermis cell
25 μg/ml
Patent: EP2467134 B1, ...
Title/Abstract Full Text Show Details
Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola
Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details
5.59
IC50
0.44
μg/ml
1-10 μg/ml
Antioxidant
Journal of Photochemistr...
Title/Abstract Full Text View citing articles Show Details
García-Bores; Espinosa-González; Reyna-Campos; Cruz-Toscano; Benítez-Flores; Hernández-Delgado; Flores-Maya; Urzúa-Meza; Peñalosa-Castro; Céspedes-Acuña; Avila-Acevedo
Journal of Photochemistry and Photobiology B: Biology, 2017 , vol. 167, p. 72 - 81 Title/Abstract Full Text View citing articles Show Details
4.57
IC50
26.8
μM
Antiplasmodic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Aldulaimi, Omar; Uche, Fidelia I.; Hameed, Hamza; Mbye, Haddijatou; Ullah, Imran; Drijfhout, Falko; Claridge, Timothy D.W.; Horrocks, Paul; Li, Wen-Wu
Journal of Ethnopharmacology, 2017 , vol. 198, p. 221 - 225 Title/Abstract Full Text View citing articles Show Details
5.51
% Inhibition
95.3
%
10 μg/ml
Antioxidant
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
25 μg/ml
Antioxidant
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
50 μg/ml
Antioxidant
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
250 μg/ml
Antioxidant
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
500 μg/ml
Antioxidant
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
125 μg/ml
Antioxidant
Archiv der Pharmazie, 20...
Title/Abstract Full Text View citing articles Show Details
12.5 25 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin
Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details
5.11
% Inhibition
95.4
%
Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin
Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details
4.81
% Inhibition
95.46
%
Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin
Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
18.96
%
Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin
Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
24.35
%
Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin
Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
15.51
%
Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin
Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details
4.13
% Inhibition
Active
RAW 264.7 cell line
Alam, Md Badrul; Kwon, Kyoo-Ri; Lee, Seok-Hyun; Lee, Sang-Han
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 266 Title/Abstract Full Text View citing articles Show Details
pX
Parameter
Value (qual)
Value (quant)
Unit
Action on Target
Target
Tissue/Organ
Cell
Bioassay
Dose
Effect
Reference (expand all/collapse all)
1
% Inhibition
18.56
%
RAW 264.7 cell line
50 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
BJ
12.5 50 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
3 -30 μg/ml
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Apoptotic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Apoptotic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Apoptotic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
Drug Research, 2017 , v...
Title/Abstract Full Text View citing articles Show Details
Alam, Md Badrul; Kwon, Kyoo-Ri; Lee, Seok-Hyun; Lee, Sang-Han
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 266 Title/Abstract Full Text View citing articles Show Details
4.13
% Inhibition
Active
Alam, Md Badrul; Kwon, Kyoo-Ri; Lee, Seok-Hyun; Lee, Sang-Han
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 266 Title/Abstract Full Text View citing articles Show Details
4.75
% Inhibition
Active
Alam, Md Badrul; Kwon, Kyoo-Ri; Lee, Seok-Hyun; Lee, Sang-Han
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 266 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
SK-MEL-28 cell line
Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
HeLa cell line
Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
A-375 cell line
Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details
5.15
EC50
1.2
μg/ml
Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details
5.08
IC50
1.4
μg/ml
Golakoti, Trimurtulu; Kancharla, Hari Krishna; Meka, Bharani; Murthy
Medicinal Chemistry Research, 2016 , vol. 25, # 12 p. 2906 - 2915 Title/Abstract Full Text View citing articles Show Details
5.05
IC50
9.01
μM
5 - 50 μM
Lone, Shabir H.; Rehman, Shakeel U; Bhat, Khursheed A.
Drug Research, 2017 , vol. 67, # 2 art. no. DRUGRES2016-06-1205, p. 111 - 118 Title/Abstract Full Text View citing articles Show Details
7.28
IC50
0.009
μg/ml
Inhibitor
Carbonic anhydrase 1 [human]:Wild
Journal of Enzyme Inhibi...
Title/Abstract Full Text View citing articles Show Details
Aygul, Imdat; Yaylaci Karahalil, Fatma; Supuran, Claudiu T.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 , vol. 31, p. 119 - 124 Title/Abstract Full Text View citing articles Show Details
6.69
IC50
0.035
μg/ml
Inhibitor
Carbonic anhydrase 2 [human]:Wild
Journal of Enzyme Inhibi...
Title/Abstract Full Text View citing articles Show Details
Aygul, Imdat; Yaylaci Karahalil, Fatma; Supuran, Claudiu T.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 , vol. 31, p. 119 - 124 Title/Abstract Full Text View citing articles Show Details
6.39
% Inhibition
~
90
%
0.625 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Mohan, Shikha; Gupta, Damodar
Biomedicine and Pharmacotherapy, 2017 , vol. 89, p. 781 - 795 Title/Abstract Full Text View citing articles Show Details
3.91
IC50
20.8
μg/ml
MDCK cell line
Anticytopathic
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Tran, Thu Thi; Kim, Meehyein; Jang, Yejin; Lee, Hye Won; Nguyen, Hoa Thi; Nguyen, Thanh Ngoc; Park, Hae Woong; Le Dang, Quang; Kim, Jin-Cheol
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 162 Title/Abstract Full Text View citing articles Show Details
3.99
IC50
17.5
μg/ml
MDCK cell line
Anticytopathic
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Tran, Thu Thi; Kim, Meehyein; Jang, Yejin; Lee, Hye Won; Nguyen, Hoa Thi; Nguyen, Thanh Ngoc; Park, Hae Woong; Le Dang, Quang; Kim, Jin-Cheol
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 162 Title/Abstract Full Text View citing articles Show Details
3.84
IC50
24.5
μg/ml
MDCK cell line
Anticytopathic
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Tran, Thu Thi; Kim, Meehyein; Jang, Yejin; Lee, Hye Won; Nguyen, Hoa Thi; Nguyen, Thanh Ngoc; Park, Hae Woong; Le Dang, Quang; Kim, Jin-Cheol
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 162 Title/Abstract Full Text View citing articles Show Details
4.43
IC50
37
μM
Antioxidant
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Kumboonma, Pakit; Senawong, Thanaset; Saenglee, Somprasong; Yenjai, Chavi; Phaosiri, Chanokbhorn
Medicinal Chemistry Research, 2017 , vol. 26, # 3 p. 650 - 661 Title/Abstract Full Text View citing articles Show Details
3.67
IC50
214.38
μM
Inhibitor
glycogen phosphorylasealpha:Wild
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Ablat, Abdulwali; Halabi, Mohammed Farouq; Mohamad, Jamaludin; Hasnan, Muhammad Hafiz Husna; Hazni, Hazrina; Teh, Ser-huy; Shilpi, Jamil A.; Mohamed, Zulqarnain; Awang, Khalijah
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 94 Title/Abstract Full Text View citing articles Show Details
3.56
IC50
277.04
μM
Inhibitor
alpha-glucosidase:Wild
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Ablat, Abdulwali; Halabi, Mohammed Farouq; Mohamad, Jamaludin; Hasnan, Muhammad Hafiz Husna; Hazni, Hazrina; Teh, Ser-huy; Shilpi, Jamil A.; Mohamed, Zulqarnain; Awang, Khalijah
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 94 Title/Abstract Full Text View citing articles Show Details
2.75
IC50
0.3
mg/ml
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Talla, Emmanuel; Tamfu, Alfred Ngenge; Gade, Isaac Sylvère; Yanda, Lambert; Mbafor, Joseph Tanyi; Laurent, Sophie; Elst, Luce Vander; Popova, Milena; Bankova, Vassya
Natural Product Research, 2017 , vol. 31, # 12 p. 1379 - 1389 Title/Abstract Full Text View citing articles Show Details
5.36
IC50
4.35
μM
Antioxidant
International Journal of...
Title/Abstract Full Text Show Details
Antioxidant
Cytotechnology, 2017 , ...
Title/Abstract Full Text View citing articles Show Details
Hamed, Manal Mortady; Abdalla, Aboelfetoh Mohamed; Ghareeb, Mosad Ahmed; Saleh, Said Abdelhalim
International Journal of Pharmacy and Pharmaceutical Sciences, 2017 , vol. 9, # 5 p. 240 - 247 Title/Abstract Full Text Show Details
2.29
IC50
876.24
μg/ml
Basu, Tapasree; Panja, Sourav; Ghate, Nikhil Baban; Chaudhuri, Dipankar; Mandal, Nripendranath
Cytotechnology, 2017 , vol. 69, # 2 p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
3.62
EC50
240
μmol/l
Antioxidant
Journal of Chromatograph...
Title/Abstract Full Text View citing articles Show Details
Li, Yuanyuan; Li, Lingxi; Cui, Yan; Zhang, Shuting; Sun, Baoshan
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017 , vol. 1054, p. 105 - 113 Title/Abstract Full Text View citing articles Show Details
Ferric reducing antioxidant power (FRAP)
7.5
μmol/l
Antioxidant
Journal of Chromatograph...
Title/Abstract Full Text View citing articles Show Details
Li, Yuanyuan; Li, Lingxi; Cui, Yan; Zhang, Shuting; Sun, Baoshan
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017 , vol. 1054, p. 105 - 113 Title/Abstract Full Text View citing articles Show Details
4.41
EC50
39
μmol/l
Antioxidant
Journal of Chromatograph...
Title/Abstract Full Text View citing articles Show Details
Li, Yuanyuan; Li, Lingxi; Cui, Yan; Zhang, Shuting; Sun, Baoshan
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017 , vol. 1054, p. 105 - 113 Title/Abstract Full Text View citing articles Show Details
% Inhibition
73.86 81.57
%
RAW 264.7 cell line
Antiinflammatory
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Low
blood
3.125 - 50 μg/ml
Immunosuppressant
3.125 - 50 μg/ml
Antiinflammatory
3.125 - 50 μg/ml
Antiinflammatory
3.125 - 50 μg/ml
Immunosuppressant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
2.91
IC50
207.38
μg/ml
peripheral blood mononuclear cell
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
3.32
IC50
81.82
μg/ml
peripheral blood mononuclear cell
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
4.83
IC50
2.53
μg/ml
blood
polymorphonuclear cell
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
4.52
IC50
5.11
μg/ml
blood
3.125 - 50 μg/ml
Immunosuppressant
3.125 - 50 μg/ml
Immunosuppressant
Antichemotactic
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
4.78
IC50
2.82
μg/ml
blood
polymorphonuclear cell
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
4.32
IC50
8.22
μg/ml
blood
polymorphonuclear cell
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
4.23
IC50
9.99
μg/ml
blood
3.125 - 50 μg/ml
Immunosuppressant
3.125 - 50 μg/ml
Antiinflammatory
6.25 μg/ml
Immunosuppressant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
3.85
IC50
24.17
μg/ml
RAW 264.7 cell line
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
% Activity
88.77
μg/ml
blood
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
3.87
% Activity
81.33
%
blood
100 μg/ml
Immunosuppressant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
3.57
% Activity
68.6
%
blood
100 μg/ml
Immunosuppressant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
4.95
% Activity
76.5
%
blood
6.25 μg/ml
Immunosuppressant
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211
Title/Abstract Full Text View citing articles Show Details
3.53
% decrease
Active
50 400 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
3.53
% Inhibition
Active
50 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
% Inhibition
High
40 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
Fold-decrease
1.98
no unit
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
Fold-decrease
1.38
no unit
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
Fold-decrease
1.07
no unit
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
Fold-decrease
1.06
no unit
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
Fold-decrease
1.04
no unit
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
% decrease
45.9
%
80 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
Fold-decrease
1.1
no unit
80
Phagocytic
Microbial Pathogenesis, ...
μg/ml
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
stoichiometric factor (n)
2.03
no unit
<= 400 μM
Antioxidant
10 μM
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Zhao, Peng-Fei; Liu, Zai-Qun
European Journal of Medicinal Chemistry, 2017 , vol. 135, p. 458 - 466 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Inhibitor
Solute carrier organic anion transporter family member 2B1:Wild
HEK293 cell line
Drug Metabolism and Phar...
Title/Abstract Full Text View citing articles Show Details
Kondo, Ayuko; Narumi, Katsuya; Ogura, Jiro; Sasaki, Ai; Yabe, Keisuke; Kobayashi, Taku; Furugen, Ayako; Kobayashi, Masaki; Iseki, Ken
Drug Metabolism and Pharmacokinetics, 2017 , vol. 32, # 2 p. 145 - 150 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Low
peritoneum macrophage
2 μM
Antiinflammatory
Patent: EP2381935 B1, ...
Title/Abstract Full Text Show Details
Antioxidant
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Lycored Ltd.; ZELKHA, Morris; LEVY, Rachel; PARAN, Esther; SHARONI, Yoav; LEVY, Joseph
Patent: EP2381935 B1, 2016 ; Title/Abstract Full Text Show Details
Equivalent amount of vitamin C
332.52
mg
Pan, Guojun; Li, Xuehui; Zhao, Long; Wu, Meng; Su, Chao; Li, Xuzhe; Zhang, Yongmin; Yu, Peng; Teng, Yuou; Lu, Kui
European Journal of Medicinal Chemistry, 2017 , vol. 138, p. 577 - 589 Title/Abstract Full Text View citing articles Show Details
% apoptosis
12.5
%
PC12
10 μM
Cytoprotective
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Pan, Guojun; Li, Xuehui; Zhao, Long; Wu, Meng; Su, Chao; Li, Xuzhe; Zhang, Yongmin; Yu, Peng; Teng, Yuou; Lu, Kui
European Journal of Medicinal Chemistry, 2017 , vol. 138, p. 577 - 589 Title/Abstract Full Text View citing articles Show Details
% apoptosis
2.8
%
PC12
100 μM
Cytoprotective
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Pan, Guojun; Li, Xuehui; Zhao, Long; Wu, Meng; Su, Chao; Li, Xuzhe; Zhang, Yongmin; Yu, Peng; Teng, Yuou; Lu, Kui
European Journal of Medicinal Chemistry, 2017 , vol. 138, p. 577 - 589 Title/Abstract Full Text View citing articles Show Details
% increase
1019
%
NHEK cell line
0.03 mg/ml
Skinprotective
Patent: US2017/112737 ...
Title/Abstract Full Text Show Details
0.0003 mg/ml
Skinprotective
Patent: US2017/112737 ...
Title/Abstract Full Text Show Details
0.01 mg/ml
Skinprotective
Patent: US2017/112737 ...
Title/Abstract Full Text Show Details
GREENPHARMA; BIOALTERNATIVES; BERNARD, Philippe; BERNARD, François-Xavier; HIMBERT, Franck
Patent: US2017/112737 A1, 2017 ; Title/Abstract Full Text Show Details
% increase
165
%
NHEK cell line
GREENPHARMA; BIOALTERNATIVES; BERNARD, Philippe; BERNARD, François-Xavier; HIMBERT, Franck
Patent: US2017/112737 A1, 2017 ; Title/Abstract Full Text Show Details
% increase
588
%
NHEK cell line
GREENPHARMA; BIOALTERNATIVES; BERNARD, Philippe; BERNARD, François-Xavier; HIMBERT, Franck
Patent: US2017/112737 A1, 2017 ; Title/Abstract Full Text Show Details
4.73
IC50
3.185
mg/l
1100 mg/l
Antioxidant
1100 mg/l
Antioxidant
1100 mg/l
Antioxidant
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Chen, Hongxia; Wang, Chengzhang; Zhou, Hao; Tao, Ran; Ye, Jianzhong; Li, Wenjun
Natural Product Research, 2017 , vol. 31, # 13 p. 1573 - 1577 Title/Abstract Full Text View citing articles Show Details
4.49
IC50
5.55
mg/l
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Chen, Hongxia; Wang, Chengzhang; Zhou, Hao; Tao, Ran; Ye, Jianzhong; Li, Wenjun
Natural Product Research, 2017 , vol. 31, # 13 p. 1573 - 1577 Title/Abstract Full Text View citing articles Show Details
4.16
IC50
11.64
mg/l
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Chen, Hongxia; Wang, Chengzhang; Zhou, Hao; Tao, Ran; Ye, Jianzhong; Li, Wenjun
Natural Product Research, 2017 , vol. 31, # 13 p. 1573 - 1577 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Active
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Active
Antioxidant
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1.83
MIC
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1.83
MIC
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
2500 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
1250 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
625 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
312.5 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
2500 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
1250 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
625 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
312.5 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
2500 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
1250 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
625 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
312.5 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
ZI
13
mm
1250 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
ZI
17
mm
2500 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
625 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
312.5 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
ZI
12
mm
1250 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
ZI
17
mm
2500 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
625 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
312.5 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
2500 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
1250 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
625 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
312.5 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
2500 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
1250 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052
Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
625 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
312.5 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
ZI
10
mm
2500 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
1250 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
625 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
ZI
Not active
312.5 μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
2500
μg/ml
Antibiotic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra
Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details
4.52
IC50
30
μM
SW1353 cell line
Antiinflammatory
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Inhibitor
nitric-oxide synthase [Mus musculus]:Wild
RAW 264.7 cell line
<= 50 μg/ml
Antiinflammatory
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
SW1353 cell line
<= 50 μg/ml
Antiinflammatory
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details
4.68
IC50
3.53
μg/ml
Antioxidant
3 Biotech, 2017 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Singh, Dhananjaya P.; Prabha, Ratna; Verma, Shaloo; Meena, Kamlesh K.; Yandigeri, Mahesh
3 Biotech, 2017 , vol. 7, # 2 art. no. 134 Title/Abstract Full Text View citing articles Show Details
4.28
IC50
8.85
μg/ml
Antioxidant
3 Biotech, 2017 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Singh, Dhananjaya P.; Prabha, Ratna; Verma, Shaloo; Meena, Kamlesh K.; Yandigeri, Mahesh
3 Biotech, 2017 , vol. 7, # 2 art. no. 134 Title/Abstract Full Text View citing articles Show Details
4.34
IC50
7.84
μg/ml
Antioxidant
3 Biotech, 2017 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Singh, Dhananjaya P.; Prabha, Ratna; Verma, Shaloo; Meena, Kamlesh K.; Yandigeri, Mahesh
3 Biotech, 2017 , vol. 7, # 2 art. no. 134 Title/Abstract Full Text View citing articles Show Details
5.38
IC50
0.71
μg/ml
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Kapepula, Paulin Mutwale; Mbombo Mungitshi, Patricia; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba Ngoyi, Dieudonné; Kalenda, Pascal Dibungi T.; Kabamba Ngombe, Nadege; Serteyn, Didier; Tits, Monique; Frédérich, Michel; Tamfum Muyembe, Jean-Jacques
Natural Product Research, 2017 , vol. 31, # 16 p. 1940 - 1943 Title/Abstract Full Text View citing articles Show Details
5.2
IC50
1.07
μg/ml
20 μl
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Kapepula, Paulin Mutwale; Mbombo Mungitshi, Patricia; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba Ngoyi, Dieudonné; Kalenda, Pascal Dibungi T.; Kabamba Ngombe, Nadege; Serteyn, Didier; Tits, Monique; Frédérich, Michel; Tamfum Muyembe, Jean-Jacques
Natural Product Research, 2017 , vol. 31, # 16 p. 1940 - 1943 Title/Abstract Full Text View citing articles Show Details
4.93
% Decrease
Active
HL-60 cell line
2-40 μg/ml
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Kapepula, Paulin Mutwale; Mbombo Mungitshi, Patricia; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba Ngoyi, Dieudonné; Kalenda, Pascal Dibungi T.; Kabamba Ngombe, Nadege; Serteyn, Didier; Tits, Monique; Frédérich, Michel; Tamfum Muyembe, Jean-Jacques
Natural Product Research, 2017 , vol. 31, # 16 p. 1940 - 1943 Title/Abstract Full Text View citing articles Show Details
Tested
Not published
RAW 264.7 cell line
Antiinflammatory
Patent: WO2017/66965 A...
Title/Abstract Full Text Show Details
THE UNIVERSITY OF HONG KONG; RONG, Jianhui
Patent: WO2017/66965 A1, 2017 ; Title/Abstract Full Text Show Details
4.05
Amount increase
Active
peritoneum macrophage
15 60 μg/ml
Phagocytic
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
peritoneum macrophage
15 μg/ml
Phagocytic
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
4.05
Amount increase
Active
peritoneum macrophage
15 μg/ml
Phagocytic
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
4.02
IC50
16.408
μg/ml
6.25 100 μg/ml
Anti-Leishmaniasis
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
3.83
% Inhibition
80
%
100 μg/ml
Anti-Leishmaniasis
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
2.98
% Inhibition
25
%
peritoneum macrophage
60 μg/ml
Anti-Leishmaniasis
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
3.52
% Inhibition
37
%
peritoneum macrophage
30 μg/ml
Anti-Leishmaniasis
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
3.95
% Inhibition
~
44
%
peritoneum macrophage
15 μg/ml
Anti-Leishmaniasis
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
4.53
IC50
5.042
μg/ml
peritoneum macrophage
15 30 μg/ml
Anti-Leishmaniasis
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
<
20
%
Inhibitor
Carboxypeptidase G2:Chimera + Guanine nucleotide exchange factor sopE2 [Sainionella typhimuriurn]:Chimera
25 μM
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Tsou, Lun K.; Yount, Jacob S.; Hang, Howard C.
Bioorganic and Medicinal Chemistry, 2017 , vol. 25, # 11 p. 2883 - 2887 Title/Abstract Full Text View citing articles Show Details
3.93
% Inhibition
Active
MCF-7 cell line
20 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
de Almeida, Thiago Silva; Neto, José Joaquim Lopes; de Sousa, Nathanna Mateus; Pessoa, Igor Parra; Vieira, Leonardo Rogério; de Medeiros, Jackeline Lima; Boligon, Aline Augusti; Hamers, Astrid R.M.; Farias, Davi Felipe; Peijnenburg, Ad; Carvalho, Ana Fontenele Urano
Biomedicine and Pharmacotherapy, 2017 , vol. 93, p. 1261 - 1268 Title/Abstract Full Text View citing articles Show Details
3.93
% Inhibition
Active
MCF-7 cell line
20 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
de Almeida, Thiago Silva; Neto, José Joaquim Lopes; de Sousa, Nathanna Mateus; Pessoa, Igor Parra; Vieira, Leonardo Rogério; de Medeiros, Jackeline Lima; Boligon, Aline Augusti; Hamers, Astrid R.M.; Farias, Davi Felipe; Peijnenburg, Ad; Carvalho, Ana Fontenele Urano
Biomedicine and Pharmacotherapy, 2017 , vol. 93, p. 1261 - 1268 Title/Abstract Full Text View citing articles Show Details
3.93
% decrease
Active
MCF-7 cell line
20 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
de Almeida, Thiago Silva; Neto, José Joaquim Lopes; de Sousa, Nathanna Mateus; Pessoa, Igor Parra; Vieira, Leonardo Rogério; de Medeiros, Jackeline Lima; Boligon, Aline Augusti; Hamers, Astrid R.M.; Farias, Davi Felipe; Peijnenburg, Ad; Carvalho, Ana Fontenele Urano
Biomedicine and Pharmacotherapy, 2017 , vol. 93, p. 1261 - 1268 Title/Abstract Full Text View citing articles Show Details
3.93
% decrease
Active
MCF-7 cell line
20 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
de Almeida, Thiago Silva; Neto, José Joaquim Lopes; de Sousa, Nathanna Mateus; Pessoa, Igor Parra; Vieira, Leonardo Rogério; de Medeiros, Jackeline Lima; Boligon, Aline Augusti; Hamers, Astrid R.M.; Farias, Davi Felipe; Peijnenburg, Ad; Carvalho, Ana Fontenele Urano
Biomedicine and Pharmacotherapy, 2017 , vol. 93, p. 1261 - 1268 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Active
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Kandikattu, Hemanth Kumar; Rachitha; Jayashree; Krupashree; Sukhith; Majid, Abdul; Amruta, Narayanappa; Khanum, Farhath
Biomedicine and Pharmacotherapy, 2017 , vol. 91, p. 191 - 201 Title/Abstract Full Text View citing articles Show Details
4.53
% Inhibition
Active
5 μg/ml
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Kandikattu, Hemanth Kumar; Rachitha; Jayashree; Krupashree; Sukhith; Majid, Abdul; Amruta, Narayanappa; Khanum, Farhath
Biomedicine and Pharmacotherapy, 2017 , vol. 91, p. 191 - 201 Title/Abstract Full Text View citing articles Show Details
4.6
% Inhibition
50
%
NPC-BM1
25 μM
Antiinvasive
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
5
% Inhibition
Active
NPC-BM1
10 50 μM
Antiinvasive
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
5
% increase
Active
NPC-BM1
10 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
5
% decrease
Active
NPC-BM1
10 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
5
% decrease
Active
NPC-BM1
10- 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
5
% decrease
Active
NPC-BM1
10- 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
5
% decrease
Active
NPC-BM1
10- 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
4.3
% decrease
Active
NPC-BM1
50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
5
% decrease
Active
NPC-BM1
10- 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
4.6
% decrease
Active
NPC-BM1
25 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
4.6
% decrease
Active
NPC-BM1
25 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
4.3
% decrease
Active
NPC-BM1
50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
4.3
% decrease
Active
NPC-BM1
50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
% decrease
20
%
NPC-BM1
10 μM
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
% decrease
40
%
NPC-BM1
25 μM
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
% decrease
70
%
NPC-BM1
50 μM
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
5
% decrease
Active
NPC-BM1
10-50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
4.3
% decrease
Active
NPC-BM1
50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
200
μM
Inhibitor
Angiotensinconverting enzyme [Leporidae]:Wild
lung
Journal of Natural Medic...
Title/Abstract Full Text View citing articles Show Details
Jenis, Janar; Kim, Jeong Yoon; Uddin, Zia; Song, Yeong Hun; Lee, Hyeong-Hwan; Park, Ki Hun
Journal of Natural Medicines, 2017 , vol. 71, # 4 p. 650 - 658 Title/Abstract Full Text View citing articles Show Details
Trolox equivalent antioxidant
1606.3
no unit
plasma
0.05 0.5 mg/ml
Antioxidant
Nutrients, 2017 , vol. ...
Title/Abstract Full Text View citing articles Show Details
capacity
Selby-Pham, Sophie N. B.; Cottrell, Jeremy J.; Dunshea, Frank R.; Ng, Ken; Bennett, Louise E.; Howell, Kate S.
Nutrients, 2017 , vol. 9, # 7 art. no. 758 Title/Abstract Full Text View citing articles Show Details
Concentration
68.7
nmol
plasma
0.05 0.5 mg/ml
Antioxidant
0.1 200 μg/ml
Antioxidant
Nutrients, 2017 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Selby-Pham, Sophie N. B.; Cottrell, Jeremy J.; Dunshea, Frank R.; Ng, Ken; Bennett, Louise E.; Howell, Kate S.
Nutrients, 2017 , vol. 9, # 7 art. no. 758 Title/Abstract Full Text View citing articles Show Details
5.14
IC50
7.2
μM
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Badral, Duger; Odonbayar, Batsukh; Murata, Toshihiro; Munkhjargal, Tserendorj; Tuvshintulga, Bumduuren; Igarashi, Ikuo; Suganuma, Keisuke; Inoue, Noboru; Brantner, Adelheid H.; Odontuya, Gendaram; Sasaki, Kenroh; Batkhuu, Javzan
Journal of Natural Products, 2017 , vol. 80, # 9 p. 2416 - 2423 Title/Abstract Full Text View citing articles Show Details
3.83
% decrease
Active
25.0 μg/ml
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
3.53
% decrease
Active
50.0 μg/ml
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
Concentration
4.03
μg/ml
25.0 μg/ml
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
Concentration
1.79
μg/ml
50.0 μg/ml
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
4.13
MIC
12.5 100
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
50 - 100
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
50 - 100
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
4.13
MIC
12.5
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
50
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
4.13
MIC
12.5 100
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
4.13
MIC
12.5 100
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
50 - 100
μg/ml
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
3.88
IC50
22.35
μg/ml
Antioxidant
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details
4.76
IC50
2.95
μg/ml
Antioxidant
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details
5.18
IC50
1.13
μg/ml
Antioxidant
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details
5.08
IC50
1.43
μg/ml
Antioxidant
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details
4.14
IC50
12.37
μg/ml
Antioxidant
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details
3.78
IC50
28.21
μg/ml
Antioxidant
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details
Catechin equivalent
6498.5
μmol/g
2.5 μg/ml
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.
Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details
5.77
IC50
1.7
μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.
Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details
6.27
IC50
0.54
μM
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.
Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details
5.72
IC50
1.9
μM
brain
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.
Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details
Trolox equivalent
8992.2
μmol/g
1 μg/ml
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.
Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details
% Inhibition
80.4
%
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.
Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details
% Inhibition
77.5
%
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.
Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details
3.75
IC50
30.31
μg/ml
Inhibitor
ATPase [Rattus norvegicus]:Wild
pancreas
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
5.06
IC50
1.48
μg/ml
Inhibitor
glucose-6phosphatase [Rattus norvegicus]:Wild
liver
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
4.59
IC50
4.4
μg/ml
pancreas
15 240 μg/ml
15 240 μg/ml
15 240 μg/ml
15 240 μg/ml
15 240 μg/ml
15 240 μg/ml
15 240 μg/ml
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
7.28
IC50
0.009
μg/ml
liver
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
3.3
IC50
85.11
μg/ml
liver
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
2.5
IC50
537.03
μg/ml
liver
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1000
μg/ml
pancreas
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
2.47
IC50
575.43
μg/ml
pancreas
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1000
μg/ml
pancreas
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
4.85
IC50
2.38
μg/ml
pancreas
15 240 μg/ml
15 240 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
1000
μg/ml
liver
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details
%
80
%
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Elansary, Hosam O.; Salem, Mohamed Z.M.; Ashmawy, Nader A.; Yessoufou, Kowiyou; El-Settawy, Ahmed A.A.
Natural Product Research, 2017 , vol. 31, # 24 p. 2927 - 2930 Title/Abstract Full Text View citing articles Show Details
4.58
IC50
4.5
μg/ml
Inhibitor
Tyrosinase [mushroom]:Wild
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Balbontin, Cristian; Avila, Jose G.; Dominguez, Mariana; Alarcon, Julio; Paz, Cristian; Burgos, Viviana; Ortiz, Leandro; Peñaloza-Castro, Ignacio; Seigler, David S.; Kubo, Isao
Food and Chemical Toxicology, 2017 , vol. 109, p. 984 - 995 Title/Abstract Full Text View citing articles Show Details
4.14
IC50
12.2
μg/ml
Antioxidant
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Balbontin, Cristian; Avila, Jose G.; Dominguez, Mariana; Alarcon, Julio; Paz, Cristian; Burgos, Viviana; Ortiz, Leandro; Peñaloza-Castro, Ignacio; Seigler, David S.; Kubo, Isao
Food and Chemical Toxicology, 2017 , vol. 109, p. 984 - 995 Title/Abstract Full Text View citing articles Show Details
5.38
IC50
0.71
μg/ml
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel
Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details
4.41
IC50
6.6
μg/ml
neutrophil
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel
Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details
5.2
IC50
1.07
μg/ml
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel
Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details
5
% Inhibition
Active
HL-60 cell line
10 500 μM
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel
Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details
6
% Inhibition
Active
Inhibitor
Myeloperoxidase:Wild
1 - 10 μM
Antiinflammatory
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel
Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details
3.91
IC50
0.021
mg/ml
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Antioxidant
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
M’sou, Soufiane; Alifriqui, Mohamed; Romane, Abderrahmane
Natural Product Research, 2017 , vol. 31, # 23 p. 2797 - 2800 Title/Abstract Full Text View citing articles Show Details
2.74
EC50
0.31
mg/ml
M’sou, Soufiane; Alifriqui, Mohamed; Romane, Abderrahmane
Natural Product Research, 2017 , vol. 31, # 23 p. 2797 - 2800 Title/Abstract Full Text View citing articles Show Details
% of cells in SUBG1 phase
<=
8.9
MDA-MB-231 cell line
%
25-50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
pX
Parameter
Value (qual)
5.3
% Increase
Active
Value (quant)
Unit
Action on Target
Target
Tissue/Organ
Cell
Bioassay
Dose
Effect
Reference (expand all/collapse all)
MDAMB-231 cell line
5-50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
MDAMB-231 cell line
50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
MDAMB-231 cell line
25 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
MDAMB-231 cell line
50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
MDAMB-231 cell line
50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
4.3
% Increase
Active
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
4.6
% Increase
Active
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% decrease
55
%
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% decrease
38
%
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% decrease
11
%
MDAMB-231 cell line
MDAMB-231 cell line
MDAMB-231 cell line
MDAMB-231 cell line
MDAMB-231 cell line
MDAMB-231 cell line
MDAMB-231 cell line
MDAMB-231 cell line
MDAMB-231 cell line
50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% decrease
41
%
50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
4.6
% increase
Active
25-50 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
Fold-increase
<=
3.22
no unit
5-50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
Fold-increase
3.16
no unit
5-50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
Fold-increase
<=
2.13
no unit
5-50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
Fold-increase
0.99
no unit
5-50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
Fold-increase
1.24
no unit
5-50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% of cells in G0/G1 phase
88.1
%
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
25-50 μmol/l
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
4
EC50
16.9
μg/ml
Antioxidant
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Guilhon-Simplicio, Fernanda; Machado, Tallita Marques; do Nascimento, Leandro Flores; Souza, Rayanne da Silva; Koolen, Hector Henrique Ferreira; da Silva, Felipe Moura Araújo; Acho, Leonard Domingo Rosales; dos Santos, Adair Roberto Soares; Cos, Paul; Pereira, Maria de Meneses; Lima, Emerson Silva
Phytotherapy Research, 2017 , vol. 31, # 11 p. 1686 - 1693 Title/Abstract Full Text View citing articles Show Details
4.86
IC50
2.34
μg/ml
Antioxidant
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Meka, Bharani; Ravada, Suryachandra Rao; Kancharla, Harikrishna; Golakoti, Trimurtulu
Medicinal Chemistry Research, 2017 , vol. 26, # 12 p. 3106 - 3124 Title/Abstract Full Text View citing articles Show Details
3.75
IC50
0.176
mM
Inhibitor
Aldose reductase [Rattus norvegicus]:Wild
liver
Antidiabetic
Journal of Enzyme Inhibi...
Title/Abstract Full Text View citing articles Show Details
Alim, Zuhal; Kilinç, Namik; Şengül, Bülent; Beydemir, Şükrü
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 , vol. 32, # 1 p. 277 - 284 Title/Abstract Full Text View citing articles Show Details
3.66
Ki
0.219
mM
Inhibitor
Aldose reductase [Rattus norvegicus]:Wild
liver
Antidiabetic
Journal of Enzyme Inhibi...
Title/Abstract Full Text View citing articles Show Details
Alim, Zuhal; Kilinç, Namik; Şengül, Bülent; Beydemir, Şükrü
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 , vol. 32, # 1 p. 277 - 284 Title/Abstract Full Text View citing articles Show Details
3.57
IC50
45.35
μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Ali, Saima; Khan, Muhammad Rashid; Sajid, Moniba
Biomedicine and Pharmacotherapy, 2017 , vol. 95, p. 1853 - 1867 Title/Abstract Full Text View citing articles Show Details
3.73
IC50
31.42
μg/ml
Inhibitor
alphaglucosidase:Wild
Antidiabetic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Şöhretoğlu, Didem; Sari, Suat; Šoral, Michal; Barut, Burak; Özel, Arzu; Liptaj, Tibor
International Journal of Biological Macromolecules, 2018 , vol. 108, p. 81 - 87 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
3.61
MIC
41.7
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
3.21
MIC
104.2
μg/ml
7.8 250
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
μg/ml
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
250
μg/ml
7.8 250 μg/ml
Antibiotic
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details
3.89
IC50
0.13
mM
0.01 2 mM
Antioxidant
AMB Express, 2017 , vol...
Title/Abstract Full Text View citing articles Show Details
Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol
AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details
3.3
% Inhibition
Active
0.5 - 5 mM
Antiperoxidant
AMB Express, 2017 , vol...
Title/Abstract Full Text View citing articles Show Details
Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol
AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details
2.7
Ki
1.98
mM
Inhibitor
Tyrosinase [mushroom]:Wild
<= 10 mM
AMB Express, 2017 , vol...
Title/Abstract Full Text View citing articles Show Details
Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol
AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details
% production
130
%
Hs 68 cell line
10 100 μM
AMB Express, 2017 , vol...
Title/Abstract Full Text View citing articles Show Details
Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol
AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details
% production
175
%
Hs 68 cell line
10 100 μM
AMB Express, 2017 , vol...
Title/Abstract Full Text View citing articles Show Details
Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol
AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details
4.88
IC50
2.25
mg/l
Antioxidant
3 Biotech, 2018 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Yuan, Shengliang; Duan, Zhihong; Lu, Yingnian; Ma, Xiaoli; Wang, Sheng
3 Biotech, 2018 , vol. 8, # 1 art. no. 8 Title/Abstract Full Text View citing articles Show Details
3.23
IC50
100
mg/l
Antioxidant
3 Biotech, 2018 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Yuan, Shengliang; Duan, Zhihong; Lu, Yingnian; Ma, Xiaoli; Wang, Sheng
3 Biotech, 2018 , vol. 8, # 1 art. no. 8 Title/Abstract Full Text View citing articles Show Details
2.83
IC50
250
mg/l
Antioxidant
3 Biotech, 2018 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Yuan, Shengliang; Duan, Zhihong; Lu, Yingnian; Ma, Xiaoli; Wang, Sheng
3 Biotech, 2018 , vol. 8, # 1 art. no. 8 Title/Abstract Full Text View citing articles Show Details
Fold-increase
2.95
no unit
Jurkat cell line
10 μM
Antineoplastic
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details
Fold-increase
3.4
no unit
Jurkat cell line
30 μM
Antineoplastic
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details
Fold-increase
4.5
no unit
Jurkat cell line
50 μM
Antineoplastic
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details
Fold-increase
6.5
no unit
Jurkat cell line
80 μM
Antineoplastic
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details
5
% Increase
Active
Jurkat cell line
10 - 50 μM
Antineoplastic
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details
4.1
% Increase
Active
Jurkat cell line
80 μM
Antineoplastic
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details
4.6
IC50
25.16
μM
<= 10 μg/ml
Antioxidant
Journal of Chromatograph...
Title/Abstract Full Text View citing articles Show Details
Peng, Jinming; Li, Kaikai; Zhu, Wei; Deng, Xiangyi; Li, Chunmei
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018 , vol. 1072, p. 78 - 85 Title/Abstract Full Text View citing articles Show Details
Reduction potential
1.91
no unit
Antioxidant
Journal of Chromatograph...
Title/Abstract Full Text View citing articles Show Details
Peng, Jinming; Li, Kaikai; Zhu, Wei; Deng, Xiangyi; Li, Chunmei
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018 , vol. 1072, p. 78 - 85 Title/Abstract Full Text View citing articles Show Details
3.7
IC50
197.92
μM
<= 200 μg/ml
Antioxidant
15-240 μg/ml
Antioxidant
Journal of Chromatograph...
Title/Abstract Full Text View citing articles Show Details
Peng, Jinming; Li, Kaikai; Zhu, Wei; Deng, Xiangyi; Li, Chunmei
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018 , vol. 1072, p. 78 - 85 Title/Abstract Full Text View citing articles Show Details
4.05
% increase
Active
liver
liver cell
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details
4.05
% increase
Active
liver
liver cell
15-240 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details
4.05
% increase
Active
liver
liver cell
15-240 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details
3.99
IC50
17.34
μg/ml
liver
liver cell
15-240 μg/ml
Antioxidant
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details
4.5
IC50
5.43
μg/ml
liver
liver cell
15-240 μg/ml
Biomedicine and Pharmaco...
Title/Abstract Full Text View citing articles Show Details
Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul
Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details
6.52
% Increase
Active
LHCNM2 cell line
0.3 - 1 μM
Antioxidant
PeerJ, 2017 , vol. 2017...
Title/Abstract Full Text View citing articles Show Details
Najjar, Fadia; Rizk, Francine; Carnac, Gilles; Nassar, Rim; Jabak, Sara; Sobolev, Anatoly Petrovich; Saada, Yara Bou; El Sabban, Marwan; Hamade, Aline
PeerJ, 2017 , vol. 2017, # 12 art. no. E4144 Title/Abstract Full Text View citing articles Show Details
% Inhibition
93.11
%
Antioxidant
PLoS ONE, 2018 , vol. 1...
Title/Abstract Full Text Show Details
Antioxidant
PLoS ONE, 2018 , vol. 1...
Title/Abstract Full Text Show Details
Antioxidant
Nature Communications, 2...
Title/Abstract Full Text View citing articles Show Details
Rasheed, Saima; Sánchez, Sara S.; Yousuf, Sammer; Honoré, Stella M.; Choudhary, M. Iqbal
PLoS ONE, 2018 , vol. 13, # 1 art. no. E0190509 Title/Abstract Full Text Show Details
4.63
IC50
23.34
μM
Rasheed, Saima; Sánchez, Sara S.; Yousuf, Sammer; Honoré, Stella M.; Choudhary, M. Iqbal
PLoS ONE, 2018 , vol. 13, # 1 art. no. E0190509 Title/Abstract Full Text Show Details
%
100
%
Faissner, Simon; Mishra, Manoj; Kaushik, Deepak K.; Wang, Jianxiong; Fan, Yan; Silva, Claudia; Rauw, Gail; Metz, Luanne; Koch, Marcus; Yong, V. Wee
Nature Communications, 2017 , vol. 8, # 1 art. no. 1990 Title/Abstract Full Text View citing articles Show Details
2.13
MIC
1.25
mg/ml
Antifungal
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details
2.44
MIC
0.625
mg/ml
Antifungal
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details
1.83
MIC50
2.5
mg/ml
Antifungal
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details
2.49
MIC90
5
mg/ml
Antifungal
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details
1.23
% decrease
Active
10 mg/ml
Antibiofilm
PLoS ONE, 2017 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi
PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
0.5
mg/ml
Antibiotic
Applied Microbiology and...
Title/Abstract Full Text Show Details
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.63
MBC
4
mg/ml
Antibiotic
Applied Microbiology and...
Title/Abstract Full Text Show Details
Antibiofilm
Applied Microbiology and...
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Antibiofilm
Applied Microbiology and...
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0.25 mg/ml
Antibiofilm
Applied Microbiology and...
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0.5 mg/ml
Antibiofilm
Applied Microbiology and...
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1 mg/ml
Antibiofilm
Applied Microbiology and...
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2 mg/ml
Antibiofilm
Applied Microbiology and...
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4 mg/ml
Antibiofilm
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0.25 mg/ml
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Applied Microbiology and...
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0.5 mg/ml
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Applied Microbiology and...
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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
MBIC
2
mg/ml
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
MBEC
8
mg/ml
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1
% Inhibition
13.27
%
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.3
% Inhibition
36.77
%
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.62
% Inhibition
70.83
%
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.67
% Inhibition
84.53
%
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.45
% Inhibition
86.83
%
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.83
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.53
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846
Title/Abstract Full Text Show Details
2.23
% decrease
Active
1 mg/ml
Antibiofilm
Applied Microbiology and...
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2 mg/ml
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Applied Microbiology and...
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4 mg/ml
Antibiofilm
Applied Microbiology and...
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0.25 mg/ml
Antibiofilm
Applied Microbiology and...
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0.5 mg/ml
Antibiofilm
Applied Microbiology and...
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1 mg/ml
Antibiofilm
Applied Microbiology and...
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2 mg/ml
Antibiofilm
Applied Microbiology and...
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4 mg/ml
Antibiofilm
Applied Microbiology and...
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1 mg/ml
Antibiofilm
Applied Microbiology and...
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2 mg/ml
Antibiofilm
Applied Microbiology and...
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4 mg/ml
Antibiofilm
Applied Microbiology and...
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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.93
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.63
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.83
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.53
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.23
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.93
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.63
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.23
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.93
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.63
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1
% decrease
Not active
0.25 mg/ml
Antibiofilm
Applied Microbiology and...
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Applied Microbiology and...
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Applied Microbiology and...
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2 mg/ml
Antibiofilm
Applied Microbiology and...
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Applied Microbiology and...
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2 mg/ml
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Applied Microbiology and...
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0.25 mg/ml
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Applied Microbiology and...
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Applied Microbiology and...
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0.25 mg/ml
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Applied Microbiology and...
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2 mg/ml
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Applied Microbiology and...
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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1
% decrease
Not active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.83
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.93
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.83
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.93
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.83
% increase
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.93
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
2.83
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
1.93
% decrease
Active
Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang
Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details
Qualitative Information 1 of 515
Effect
Antibiotic
Biological material
Gardnerella vaginalis
Assay Description
2 of 515
3 of 515
4 of 515
5 of 515
Bioassay : EXAMPLE 6 The ability of the vaginal treatment composition of the present invention to inhibit and/or treat vaginal infection was demonstrated. Initially, eight (8) solutions were formed as set forth below in Table 4. ; Samples 1-2 were prepared by dissolving the KELCOGEL&reg; (0.07 grams) and/or xylitol
Results
average plate count=3.43*10E4
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2007/26074 A1, 2007 ; Title/Abstract Full Text Show Details
Effect
Antiviral
Biological material
human
Assay Description
Effect : anti-viral Species : Human papillomavirus (HPV) 16/18 Example 4. Drug screening through quantitative fluorescent PCR analysis Samples The micro emulsions obtained in Example 1 were used as test samples, and saline water was used as the control. HPV samples: condyloma acuminata samples were taken from clinical patients. The samples were washed with saline
Results
treatment with the title compound at 50μl micro emulsion effectively and rapidly eliminated the number of human papillomavirus (HPV) 16/18 from 1.40E5 (control) to 0copies/ml
Citation
SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antiviral
Biological material
human
Assay Description
Effect : anti-viral Species : Human papillomavirus (HPV) 6/11 Example 4. Drug screening through quantitative fluorescent PCR analysis Samples The micro emulsions obtained in Example 1 were used as test samples, and saline water was used as the control. HPV samples: condyloma acuminata samples were taken from clinical patients. The samples were washed with saline
Results
treatment with the title compound at 50μl micro emulsion effectively and rapidly eliminated the number of human papillomavirus (HPV) 6/11 from 1.45E6 (control) to 0copies/ml
Citation
SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
human
Assay Description
Effect : adverse effect Example 5. Clinical use of hydroxybenzoic acid ester in treating condyloma acuminata Diagnosis standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of
Results
treatment with the title compound did not cause any obvious skin irritation however some patients ocassionally experienced a burning sense
Citation
SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
human
6 of 515
7 of 515
8 of 515
Assay Description
Effect : condyloma acuminata; effect on Example 5. Clinical use of hydroxybenzoic acid ester in treating condyloma acuminata Diagnosis standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of
Results
treatment with the title compound showed that in 50 qualified patients, 2 had recovered within 1-4 days, obvious effects were seen in 3 (1-4 days) and 1 (5-8 days) patient, 4 patients had improved effect
Citation
SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : HBeAg secretion; inhibition of Bioassay : liver 2.2.15 cells transfected by hepatitis B virus (HBV) DNA Example 6. Inhibition effect of hydroxybenzoic acid ester analogue on secretion of HBsAg by hepatitis B 2.2.15 cell line Experiment materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological Sciences
Results
treatment with the title compound at 2μmol/ml inhibited the rate of HBeAg secretion measured as 9.40% inhibition rate (control=0%)
Citation
SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : HBsAg secretion; inhibition of Bioassay : liver 2.2.15 cells transfected by hepatitis B virus (HBV) DNA Example 6. Inhibition effect of hydroxybenzoic acid ester analogue on secretion of HBsAg by hepatitis B 2.2.15 cell line Experiment materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological Sciences
Results
treatment with the title compound at 2μmol/ml inhibited the rate of HBsAg secretion measured as 8.83% inhibition rate (control=0%)
Citation
SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antimutagenic
Assay Description
9 of 515
10 of 515
Target : Salmonella typhimurium TA 100 Bioassay : inhibition of direct-acting mutagenicity of 4-NQO 4-nitroquinoline (4-NQO) as mutagenic agent; standard plate incorporation assay; 37 deg C
Citation
De Flora; Rosenkranz; Klopman
Mutagenesis, 1994 , vol. 9, # 1 p. 39 - 45 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; examination of Bioassay : developing, lignifying xylem; Concanavalin-A bound fraction of xylem extract response of xylem oxidase activity (OA) to title comp. as effector; OA measured against 2,2'-azinobis(3ethylbenzothiazoline-6-sulfonic acid (ABTS
Results
almost complete inhibition of OA in presence of title comp. to 3.3 percent of control value
Citation
Deighton, Nigel; McDougall, Gordon J.
Phytochemistry, 1998 , vol. 48, # 4 p. 601 - 606 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; examination of Bioassay : in vitro; enzyme activity for title comp. assayed according to spectrophotometric procedure; sodium acetate buffer, pH 4.0; 25 deg C; increase in absorbance of oxidation product measured for 3 min
Citation
Paul, Beena; Gowda, Lalitha R.
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 9 p. 3839 - 3846 Title/Abstract Full Text View citing articles Show Details
11 of 515
Effect Assay Description
12 of 515
13 of 515
14 of 515
15 of 515
16 of 515
Target : Escherichia coli strain WP2mutT Bioassay : changed color from purple to yellow due to growth of spontaneous trp+ revertants in culture indicated that spontaneous mutation was not suppressed by title comp.; suppressive ability represented by number of trp+ revertant; control to water sample Mut-Test: 0.4 ml of culture of strain WP2mutT with high spontaneous mutation, 0.25 mg/l of triptophan, 5 mg/l of bromocresol purple (as indicator), 0.4 ml of title comp. solution; incubation at 37 deg C; conc. dependence investigated
Citation
Strange, Richard C.; Spiteri, Monica A.; Ramachandran, Sudarshan; Fryer, Anthony A.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2001 , vol. 482, # 1-2 p. 21 - 26 Title/Abstract Full Text View citing articles Show Details
Results
inhibit effect on glutathione S-transferase and glutathion reductase activities
Citation
Iio; Kawaguchi; Sakota; Otonari; Nitahara
Bioscience, Biotechnology and Biochemistry, 1993 , vol. 57, # 10 p. 1678 - 1680 Title/Abstract Full Text View citing articles Show Details
Results
inhibitory effect on mushroom tyrosinase, IC 50, mM: 5.91 (spectrophometric method), 16.5 (polarographic method); mixed type of inhibition, inhibition dissociation constant Ki 1.10 mM (spectrophotometric method), 9.69 mM (polarographic method)
Citation
Kermasha, Selim; Goetghebeur, Mireille; Monfette, Alan; Metche, Maurice; Rovel, Bernard
Phytochemistry (Elsevier), 1993 , vol. 34, # 2 p. 349 - 354 Title/Abstract Full Text View citing articles Show Details
Results
appearance of laccase activity
Citation
Viterbo, Ada; Yagen, Boris; Mayer, Alfred M.
Phytochemistry (Elsevier), 1993 , vol. 34, # 1 p. 47 - 50 Title/Abstract Full Text View citing articles Show Details
Results
effect on the growth of pollen tube of Camellia japonica
Citation
Ozawa; Takeshita; Negishi; Imagawa
Bioscience, Biotechnology and Biochemistry, 1993 , vol. 57, # 12 p. 2122 - 2126 Title/Abstract Full Text View citing articles Show Details
Effect
Antifeedant
Assay Description
17 of 515
Antimutagenic
Target : Malacosoma disstria Hubner, forest tent caterpillar Bioassay : leaf disks were photocopied; the percentage of each disk remaining was determined with a Image Analyser; the antifeedant index for each plate was calculated egg bands collected from trembling aspen trees from Cochrane and Thunder Bay, Ontario, Canada; larvae were reared in envirom. chambers at 21 deg C, 80 percent rel. chum., 16L:8D; second leaf disk assay method; 5 newly molted fourth-instar larvae; 24-h test
Results
antifeedant index 33.7 percent
Citation
Abou-Zaid; Helson; Nozzolillo; Arnason
Journal of chemical ecology, 2001 , vol. 27, # 12 p. 2517 - 2527 Title/Abstract Full Text View citing articles Show Details
Effect
Immunostimulant
Biological material
RAW 264.7 cell line
Assay Description
Bioassay : expression profiles compared with those mediated by IFN-γ and LPS; iNOS: inducible NO synthase; IL: interleukin; IFN: interferon; TNF: tumor necrosis factor; RT-PCR: reverse-transcription polymerase chain reaction; LPS: lipopolysacchride expression of iNOS and cytokine IL, IFN, TNF transcripts simulated with title comp. in non-infected and Leishmania-infected test cells studied using RT-
PCR reaction; PCR products separated on agarose gel and quantified by densitometric analysis
18 of 515
19 of 515
Results
results given as percent density of iNOS and cytokine IL-1, IL-12, IL-18, TNF, INF-α, INF-γ in noninfected and infected test cells relative to hypoxanthin-guanine-phosphoribosyl transferase (HGPRT) mRNA defined as 100 percent
Citation
Kolodziej, Herbert; Kiderlen, Albrecht F.
Phytochemistry, 2005 , vol. 66, # 17 SPEC. ISS. p. 2056 - 2071 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |transmitter release; inhibition of Target : human aortic vascular smooth muscle cells Bioassay : vehicle control; PDGFAB: platelet-derived growth factorAB; VEGF: vascular endothelial growth factor cells were exposed to title comp. for 30 min; incubation with PDGFAB (30 ng/ml) for 24 h; VEGF release into medium; immunoassay
Results
title comp. increased basal release of VEGF, but did not change stimulatoty effect of PDGFAB on VEGF level (figure)
Citation
Oak; Bedoui; Madeira; Chalupsky; Schini-Kerth
British Journal of Pharmacology, 2006 , vol. 149, # 3 p. 283 - 290 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
20 of 515
Citation
Oak; Bedoui; Madeira; Chalupsky; Schini-Kerth
British Journal of Pharmacology, 2006 , vol. 149, # 3 p. 283 - 290 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
21 of 515
Target : human aortic vascular smooth muscle cells Bioassay : vehicle control; PDGFAB: platelet-derived growth factorAB; EPR: electron paramagnetic resonance; ROS: reactive oxygen species; TEMPONE-H: 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine; reference comp.: superoxide dismutase cells were treated with title comp. for 30 min; incubation with PDGFAB (30 ng/ml) for 24 h; direct ROS-scavenging activity; EPR-spin trapping method with TEMPONE-H and potassium superoxide
Results
title comp. reduced ROS level stimulated by PDGFAB; reference comp. had similar effect (figure)
Citation
Oak; Bedoui; Madeira; Chalupsky; Schini-Kerth
British Journal of Pharmacology, 2006 , vol. 149, # 3 p. 283 - 290 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Assay Description
22 of 515
Target : human aortic vascular smooth muscle cells Bioassay : vehicle control; PDGFAB: platelet-derived growth factorAB; DCF: dichlorofluorescein; ROS: reactive oxygen species cells were loaded with 10 μmol/l DCF for 30 min at 37 deg C; treatment with title comp. for 30 min; incubation with PDGFAB (30 ng/ml) for 1 h; generation of ROS was assessed using DCF fluorescence
Target : lymphocytes of human Bioassay : intact cells used as negative controls; mitomycin C-treated cells used as positive controls blood from healthy donors; cultured with comp. alone or in the presence of mitomycin C; metaphases blocked and frequency of sister chromatid exchange determined
Results
title comp. enhanced mitomycin C-induced clastogenicity and alone had no genotoxic activity; tab.
Citation
Stagos, Dimitrios; Spanou, Chrysa; Margariti, Maria; Stathopoulos, Constantinos; Mamuris, Zissis; Kazantzoglou, Georgios; Magiatis, Prokopios; Kouretas, Demetrios
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 13 p. 5246 - 5252 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
23 of 515
Results
title comp. was effective antioxidant against AAPH-induced microsomal peroxidation; antioxidant synergism with endogenous TOH was due to reduced initiation rate caused by title comp. due to trapping initiating radicals in bulk water phase
Citation
Cai, Yu-Jun; Ma, Lan-Ping; Hou, Li-Fen; Zhou, Bo; Yang, Li; Liu, Zhong-Li
Chemistry and Physics of Lipids, 2002 , vol. 120, # 1-2 p. 109 - 117 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
24 of 515
26 of 515
Target : HIT cells Bioassay : then washed with PBS and challenged with 4E-4 Sigma units glucose oxidase (GO) plus 30 μmol/l metMb in fresh medium for 20 h; 1 μCi/well <3H>thymidine added 18 h before cell harvesting ability to protect cells from H2O2/metmyoglobin (metMb) ferryl stress assessed measuring cell proliferation by <3H>thymidine incorporation assay; 3E5 cells/well; 30 μmol/l metMb; DMEM with 10 percent FCS; 37 deg C; incubated for 24 h
Citation
Lapidot, Tair; Walker, Michael D.; Kanner, Joseph
Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 25 p. 7220 - 7225 Title/Abstract Full Text View citing articles Show Details
Effect
Antiproliferative
Assay Description
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Target : Wistar rat liver microsomes Bioassay : 37 deg C; title comp. added before or after AAPH initiation; synergism with endogenous α-tocopherol (TOH) studied in vitro; effect on free radical-initiated microsomal peroxidation evaluated by oxygen uptake and malondialdehyde formation measurements; 8 mmol/l 2,2'-azobis(2-amidinopropane hydrochloride) (AAPH) used as initiator; potassium phosphate buffer, pH 7.4
Target : HIT cells Bioassay : without or with 30 μmol/l metmyoglobin added simultaneously with title comp. effect on cell proliferation assessed using <3H>thymidine incorporation assay; 3E5 cells/well; DMEM with 10 percent FCS; 37 deg C; incubated for 20 h; 1 μCi/well <3H>thymidine added 18 h before cell harvesting
Results
title comp. produced significant proliferation inhibition, which was reduced by inclusion of metmyoglobin
Citation
Lapidot, Tair; Walker, Michael D.; Kanner, Joseph
Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 25 p. 7220 - 7225 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : enzyme activity; inhibition of Bioassay : lansoprazole used as reference comp. incubated with title comp. in the presence substrate 2mM ATP at 37 deg C for 30 min; H+,K+-ATPase inhibition assessed by spectrophotometric measurements at 400 nm of released inorganic phosphate
Results
title comp. IC50 132.0 μg/ml (vs. 19.3 μg/ml for lansoprazole)
Citation
Siddaraju; Dharmesh, Shylaja M.
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7377 - 7386 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Biological material
Helicobacter pylori
Assay Description
Bioassay : 10 μg/ml amoxicillin used as reference comp.; 0.9% saline-treated negative controls Gram-negative bacterium obtained by endoscopic samples of ulcer patients; standard agar diffusion method; zone of inhibition around disks placed on inoculated plates measured
Results
title comp. produced zone of inhibition of 14 mm (44% inhibition) vs. 36 mm (78% inhibition) for amoxicillin
Citation
Siddaraju; Dharmesh, Shylaja M.
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7377 - 7386 Title/Abstract Full Text View citing articles Show Details
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Effect
Antibiotic
Biological material
Helicobacter pylori
Assay Description
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Results
title comp.-treated cells changed (similarly to amoxicillin treated ones) from helical form to coccoid form and became necrotic; fig.
Citation
Siddaraju; Dharmesh, Shylaja M.
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7377 - 7386 Title/Abstract Full Text View citing articles Show Details
Effect
Toxic
Assay Description
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inhibition zone diameter was 23 and > 40 mm at 27 and 160 μg, resp. (table)
Citation
Walenciak, Oliver; Zwisler, Walter; Gross, Elisabeth M.
Journal of Chemical Ecology, 2002 , vol. 28, # 10 p. 2045 - 2056 Title/Abstract Full Text View citing articles Show Details
Effect
Toxic
Target : Comamonas sp. Bioassay : closest relative strain characterized; larvae fed with Myriophyllum spicatum or Potamogeton perfoliatus bacteria isolated from gut microbiota of larvae of aquatic moth Acentria ephemerella; title comp. applied to CPS agar plates (alkaline media) incubated with bacteria at 24 deg C for 48 h; inhibition zone diameter determ.
Results
inhibition zone diameter was 13 and > 40 mm at 27 and 160 μg, resp. (table)
Citation
Walenciak, Oliver; Zwisler, Walter; Gross, Elisabeth M.
Journal of Chemical Ecology, 2002 , vol. 28, # 10 p. 2045 - 2056 Title/Abstract Full Text View citing articles Show Details
Effect
Toxic
Biological material
Pseudomonas
Assay Description
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Target : Chryseobacterium sp. Bioassay : closest relative strain characterized; larvae fed with Myriophyllum spicatum; bacteria also isolated from leaves of Potamogeton perfoliatus bacteria isolated from gut microbiota of larvae of aquatic moth Acentria ephemerella or from food plants leaves; title comp. applied to CPS agar plates (alkaline media) incubated with bacteria at 24 deg C for 48 h; inhibition zone diameter determ.
Results
Assay Description
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Bioassay : 10-30 μg/ml amoxicillin used as reference comp.; untreated control cells Gram-negative bacterium obtained by endoscopic samples of ulcer patients; cultured with title comp. at 37 deg C for 6 h; changes in cell morphology assessed by using scanning electron microscopy
Bioassay : closest relative strain characterized; larvae fed with Potamogeton perfoliatus bacteria isolated from gut microbiota of larvae of aquatic moth Acentria ephemerella; title comp. applied to CPS agar plates (alkaline media) incubated with bacteria at 24 deg C for 48 h; inhibition zone diameter determ.
Results
inhibition zone diameter was 26 and > 40 mm at 27 and 160 μg, resp. (table)
Citation
Walenciak, Oliver; Zwisler, Walter; Gross, Elisabeth M.
Journal of Chemical Ecology, 2002 , vol. 28, # 10 p. 2045 - 2056 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Results
Target : Sprague-Dawley rat liver microsomes Bioassay : enzymatic lipid peroxidation (LPO) studied; microsomes incubated with NADPH generating system in the presence or absence of title comp.; pH 7.4, 37 deg C, 30 min; LPO assayed by estimation of thiobarbiturate reacting substances (TBARS) slight effect; 10 μmol/l title comp. inhibited TBARS formation by 7 percent compared to control; diagram given
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Citation
Gyamfi, Maxwell Afari; Aniya, Yoko
Biochemical Pharmacology, 2002 , vol. 63, # 9 p. 1725 - 1737 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Target : Sprague-Dawley rat liver microsomes Bioassay : non-enzymatic lipid peroxidation (LPO) studied; microsomes incubated with FeSO4 and ascorbate in the presence or absence of title comp.; pH 7.4, 37 deg C, 20 min; LPO assayed by estimation of thiobarbiturate reacting substances (TBARS)
Results
concentration-dependent effect; 10 μmol/l title comp. inhibited TBARS formation by 7 percent compared to control; diagram given
Citation
Gyamfi, Maxwell Afari; Aniya, Yoko
Biochemical Pharmacology, 2002 , vol. 63, # 9 p. 1725 - 1737 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : pooled microsomes from seven individuals title comp. preincubated with microsomes in the presence or absence of NADPH; then incubated with isocitrate, isocitrate dehydrogenase, MgCl2, NADP and <14C>androstenedione for 10 min at 37 deg C; products separated by TLC; scintillation spectrometry
Results
title comp. significantly inhibited androstenedione 6β-hydroxylase activity (nmol/mg protein/min) from 0.53 and 0.43 to 0.20 and 0.03 in the presence and absence of NADPH, respectively; no inhibition after removal title comp.-derived products
Citation
Stupans; Tan; Kirlich; Tuck; Hayball; Murray
Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; examination of Bioassay : pooled microsomes from seven individuals; effect on CYP content examined title comp. preincubated with microsomes in the presence or absence of NADPH; CO-reduced CYP difference spectra recorded; CYP content evaluated
Citation
Stupans; Tan; Kirlich; Tuck; Hayball; Murray
Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : pooled microsomes from seven individuals; chlorzoxazone 6-hydroxylase activity assayed microsomes preincubated with title comp. in the presence or absence of NADPH for 15 min; then mixture incubated with isocitrate, isocitrate dehydrogenase, MgCl2, NADP and <2-14C>chlorzoxazone for 20 min at 37 deg C
Citation
Stupans; Tan; Kirlich; Tuck; Hayball; Murray
Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : pooled microsomes from seven individuals; ethoxyresorufin-O-deethylase activity assayed microsomes and title comp. preincubated with and without NADPH for 15 min; then mixture incubated with isocitrate, isocitrate dehydrogenase, MgCl2, NADP and ethoxyresorufin for 15 min at 37 deg C; resorufin quantified by fluorescence spectrophotometry
Citation
Stupans; Tan; Kirlich; Tuck; Hayball; Murray
Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
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Assay Description
Effect : |enzyme; inhib. of Bioassay : pooled microsomes from seven individuals microsomes preincubated with title comp. in the presence or absence of NADPH for 15 min; mixture diluted, substrate and generating system added; 17β-hydroxysteroid dehydrogenase activity determined
Citation
Stupans; Tan; Kirlich; Tuck; Hayball; Murray
Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : fibril formation Target : β-amyloid (1-42) Bioassay : PBS; room temp.; incubated for 1 h; aggregation of peptide measured by thioflavin fluorescence assay
Citation
Kim, Hee; Park, Byeoung-Soo; Lee, Kwang-Geun; Cheol, Yong Choi; Sung, Sik Jang; Kim, Young-Ho; Lee, Sung-Eun
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 22 p. 8537 - 8541 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |biotransformation Target : Lactobacillus hilgardii 5w Bioassay : complex FT80 medium, pH 5.0; microaerophilic conditions; 30 deg C; incubated in darkness for 48 h; HPLC analysis of metabolites
Results
title comp., pyrogallol, catechol, protocatechuic acid, p-hydroxybenzoic acid, p-hydroxybenzaldehyde, and p-hydroxybenzyl alcohol were detected in incubation medium Further metabolite(s)
Citation
Alberto, Maria R.; Gomez-Cordoves, Carmen; Manca De Nadra, Maria C.
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 21 p. 6465 - 6469 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : protein; binding to Target : Lactobacillus hilgardii 5w Bioassay : adsorption on cell walls evaluated; ca. 2E8 heat-inactivated cells/ml; complex FT80 medium, pH 5.0; 30 deg C; incubated for 48 h; conc. of title comp. in culture-free supernatant measured
Citation
Alberto, Maria R.; Gomez-Cordoves, Carmen; Manca De Nadra, Maria C.
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 21 p. 6465 - 6469 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : oxygen radical absorbance capacity Bioassay : 2,2'-azobis(2-amidinopropane) dihydrochloride 1 ORAC unit corresponded to the inhibition of declining fluorescence produced by 1 μmol/l of Trolox
Results
ORAC units 1.94 units
Citation
Pfundstein, Beate; El Desouky, Samy K.; Hull, William E.; Haubner, Roswitha; Erben, Gerhard; Owen, Robert W.
Phytochemistry, 2010 , vol. 71, # 10 p. 1132 - 1148 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : oxygen radical
Results
ORAC oxygen radical absorbance capacity 6.4 mmol Trolox equivalent/g
Citation
Huang, Yong-Lin; Tsujita, Takaaki; Tanaka, Takashi; Matsuo, Yosuke; Kouno, Isao; Li, Dian-Peng; Nonaka, Gen-Ichiro
Phytochemistry, 2011 , vol. 72, # 16 p. 2006 - 2014 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative
Bioassay : Ce(SO4)2*4 H2O CERAC assay; CERAC: Ce(IV)-based reducing capacity; TEAC: trolox equivalent antioxidant capacity; TEAC coefficient: ratio of slope of spectrofluorometric titration curve of tested antioxidant to that of trolox; TEAC coefficient determined by fluorescence method or absorptimetric assay
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Results
TEAC coefficient 2.02 - 3.27
Citation
Ozyurt, Dilek; Demirata, Birsen; Apak, Resat
Journal of Fluorescence, 2011 , vol. 21, # 6 p. 2069 - 2076 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : CuCl2
CUPRAC assay; CUPRAC: CUPric reducing antioxidant capacity; TEAC: trolox equivalent antioxidant capacity; TEAC coefficient: ratio of slope of spectrofluorometric titration curve of tested antioxidant to that of trolox
Results
TEAC coefficient 2.6
Citation
Ozyurt, Dilek; Demirata, Birsen; Apak, Resat
Journal of Fluorescence, 2011 , vol. 21, # 6 p. 2069 - 2076 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : radical scavenging Bioassay : ABTS TEAC: trolox equivalent antioxidant capacity; TEAC coefficient: ratio of slope of spectrofluorometric titration curve of tested antioxidant to that of trolox
Results
TEAC coefficient 3
Citation
Ozyurt, Dilek; Demirata, Birsen; Apak, Resat
Journal of Fluorescence, 2011 , vol. 21, # 6 p. 2069 - 2076 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Biological material
Salmonella enterica serovar Typhimurium
Assay Description
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Citation
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Biological material
Bacteroides fragilis
Assay Description
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Bioassay : growth inhibition test; spectrophotometry
Bioassay : growth inhibition test; spectrophotometry
Citation
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Biological material
Clostridium perfringens
Assay Description
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Citation
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Assay Description
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Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Target : Enterobacter cloacae ATCC 13047 Bioassay : growth inhibition test; spectrophotometry
Citation
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Assay Description
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Target : Clostridium paraputrificum ATCC 25780 Bioassay : growth inhibition test; spectrophotometry
Citation
Assay Description
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Target : Clostridium clostridiiforme ATCC 25537 Bioassay : growth inhibition test; spectrophotometry
Citation
Assay Description
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Target : Bifidobacterium infantis ATCC 15697 Bioassay : growth inhibition test; spectrophotometry
Citation
Assay Description
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Bioassay : growth inhibition test; spectrophotometry
Target : Lactobacillus acidophilus ATCC 4356 Bioassay : growth inhibition test; spectrophotometry
Citation
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Assay Description
Target : Salmonella typhimurium YG1041
Bioassay : growth inhibition test; spectrophotometry
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Citation
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Biological material
Escherichia coli
Assay Description
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Bioassay : growth inhibition test; spectrophotometry
Citation
Chung; Lu; Chou
Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details
Results
contents in stems of in vitro grown shoots
Citation
Scalbert, Augustin; Monties, Bernard; Favre, Jean-Michel
Phytochemistry (Elsevier), 1988 , vol. 27, # 11 p. 3483 - 3488 Title/Abstract Full Text View citing articles Show Details
Results
enzyme inhibitory effect on grape catechol oxidase
Citation
Gunata, Yusuf Z.; Sapis, Jean-Claude; Moutounet, Michel
Phytochemistry (Elsevier), 1987 , vol. 26, # 6 p. 1573 - 1576 Title/Abstract Full Text View citing articles Show Details
Results
no significant inhibition of α-amylase, ID50: > 1000 μM
Citation
Hara, Yukihiko; Honda, Miwa
Agricultural and Biological Chemistry, 1990 , vol. 54, # 8 p. 1939 - 1945 Title/Abstract Full Text Show Details
Assay Description
Effect : tumor necrosis factor alpha (TNF-α) biosynthesis; inhibition of Target : keratinocytes of human Bioassay : [Experimental example 10] Measurement of inhibition effect on biosynthesis of tumor necrosis factor alpha (TNF-α) by UV irradiation Human keratinocytes were cultured in a 12-well plate type incubator at a concentration of 104. The plate was irradiated by UV-B at 30mJ/cπf. The media
Results
10μM of the title compound produced 36% TNF-α as compared to 100% of the UV control
Citation
AMOREPACIFIC CORPORATION
Patent: WO2007/29982 A1, 2007 ; Title/Abstract Full Text Show Details
Assay Description
Effect : type I collagenase (MMP-1) biosynthesis; effect on Target : fibroblasts of human Bioassay : [Experimental example 11] Measurement of inhibition effect on biosynthesis of Type I collagenase (MMP-I) by UV irradiation Human fibroblasts isolated from the skin of new born baby were cultured in a48-well plate type incubator at a concentration of 104. after 24 hours, the plate was irradiated
Results
10 ppm of the title compound produced 52% type IV collagen (w/ UV-A irradiated group) and 89% type IV collagen (w/ UV-A+TNF-α treated group) as compared to 100% and 124% of the control, respectively
Citation
AMOREPACIFIC CORPORATION
Patent: WO2007/29982 A1, 2007 ; Title/Abstract Full Text Show Details
Target
Peroxisome proliferator-activated receptor, alpha:Wild
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Assay Description
Effect : Peroxisome Proliferator Activated Receptor-α (PPAR-α) activation; effect on Bioassay : [Experimental example 9] Test of activation of PPAR-α (Peroxisome Proliferator Activated Receptor-alpha) playing a role in promotion of differentiation/inhibition of multiplication of dermal cells and promotion of lipid biosynthesis and prevention of inflammationMonkey kidney epithelial cell line
Results
1.3-1.7 PPAR-α activity was measured at 10-100μM of the title compound
Citation
AMOREPACIFIC CORPORATION
Patent: WO2007/29982 A1, 2007 ; Title/Abstract Full Text Show Details
Target
lipase:Wild
Assay Description
Effect : lipase; inhibition of Bioassay : Lipase activity measurement was carried out by using oleic acid ester of fluorescence 4-methylumbelliferone (4-UMO) as a substrate, and measuring the fluorescence of 4-methylumbelliferone produced by reaction. In the measurement, 13 mM Tris-HCl containing 150 mM NaCl and 1.36 mM CaCl2 was
Citation
SUNTORY LIMITED
Patent: EP1783136 A1, 2007 ; Title/Abstract Full Text Show Details
Results
active inhibitor of the nitrite oxidation of oxyhemoglobin
Citation
Kostenko, L. Kh.; Rozantsev, E. G.; Savel'ev, V. A.
Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 12 p. 904 - 907Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 12 p. 1458 - 1461 Title/Abstract Full Text View citing articles Show Details
Results
gastroprotective activity, adrenoprolonging action (rats and mice)
Citation
Barnaulov, O. D.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 6 p. 427 - 430Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 6 p. 689 - 692 Title/Abstract Full Text View citing articles Show Details
Biological material
Mus musculus RAW 264.7 cell line
Assay Description
Effect : gene expression; inhibition of Bioassay : control: vehicle; NF: nuclear factor; LPS: lipopolysaccharide; cells transfected with NF-κB luciferase reporter gene and pSV-β-Galactosidase Control Vector; reference comp.: oleanolic acid, ursolic acid, pyrrolidine dithiocarbamate (NF-κβ inhibitor) cultured in DMEM at 37 deg C; treated for 2 h with title comp. prior to 23 h treatment with LPS; after 24 h, cells lysed and assayed for luciferase and β-galactosidase activities using Bright-Glo Luciferase Assay System and Beta-Glo Assay System
Results
title comp. inhibited lipopolysaccharide-induced NFκB promoter activity (figure); effect was significant at dose of 300 μg/ml
Citation
Huang, Tom H. W.; Yang, Qinglin; Harada, Masaki; Li, George Q.; Yamahara, Johji; Roufogalis, Basil D.; Li, Yuhao
Journal of Cardiovascular Pharmacology, 2005 , vol. 46, # 6 p. 856 - 862 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
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Target : Salmonella typhimurium TA980 Bioassay : mutagens used: 2-nitrofluorene, 2-nitro-p-phenylenediamine, 3-nitro-and 4-nitro-o-phenylenediamines, 4,4'-dinitro-2-biphenylamine, 1-nitropyrene, 1,3-dinitropyrene, benzidine, 4aminobiphenyl, 3,3',4,4'-tetraaminobiphenyl, N,N,N',N'-tetramethylbenzidine Ames test; standard incorporation and preincubation procedures; in the abs. and pres. of S9 mix; mutagens added and preincub. for 30 min before plating
Citation
Grice; Goldsmith
Food and Chemical Toxicology, 2000 , vol. 38, # SUPPL. 2 p. 1 - 6 Title/Abstract Full Text View citing articles Show Details
Effect
Mutagenic
Biological material
Salmonella enterica serovar Typhimurium
Assay Description
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Citation
Grice; Goldsmith
Food and Chemical Toxicology, 2000 , vol. 38, # SUPPL. 2 p. 1 - 6 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : in vitro; potassium phosphate buffer (pH 6.3); maltose as substrate
Results
inhibitory activity of title comp. 4.3 percent
Citation
Toda; Kawabata; Kasai
Bioscience, biotechnology, and biochemistry, 2001 , vol. 65, # 3 p. 542 - 547 Title/Abstract Full Text Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : in vitro; potassium phosphate buffer (pH 6.3); sucrose as substrate
Results
inhibitory activity of title comp. 8.12
Citation
Toda; Kawabata; Kasai
Bioscience, biotechnology, and biochemistry, 2001 , vol. 65, # 3 p. 542 - 547 Title/Abstract Full Text Show Details
Effect
Immunostimulant
Assay Description
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Bioassay : Ames test; standard preincubation procedures in the abs. and pres. of liver S9 mix; 2-aminofluorene, 2-nitrofluorene and N-methyl-N-nitro-N'-nitrosoguanidine as reference comp.
Target : murine macrophage (RAW 264.7) cells Bioassay : tumor necrosis factor (TNF-)α, interferon (IFN) release determined using murine L929 fibroblast cytotoxicity assays cells incub. with title comp. in R10 medium (37 deg C; 5 percent CO2, 48 h <NO>; 6 percent CO2, 18 h <TNF-α>; 48 h <IFN>); NO production measured by the Griess assay
Results
at 50 mg/l: 54.0 μmol/l NO produced; EC50, μg/ml: 25.0 <TNF-α>; 0.7 <IFN>
Citation
Kolodziej; Kayser; Kiderlen; Ito; Hatano; Yoshida; Foo
Planta Medica, 2001 , vol. 67, # 9 p. 825 - 832 Title/Abstract Full Text View citing articles Show Details
Biological material
RAW 264.7 cell line
Assay Description
Effect : |metabolic Bioassay : 5 percent CO2 atmosphere; NO production measured using Griess reagent in vitro; inhibition of LPS/IFN-γ-stimulated NO production assayed; 6E5 cells/well preincubated with title comp. for 1 h before stimulation with 10 ng/mL LPS and 10-50 units/mL IFN-γ; activated cells were further incubated for 24 h; DMEM; 37 deg C
Results
title comp. inhib. NO production in a dose-dependent manner; nitrite conc. (μM)/dose (μM): 49.7/16, 53.6/31, 46.9/63, 43.8/125, 34.0/250, and 13.4/500 (control: 46.2); inhib. effect for 250 μM dose: ca. 27 percent and for 500 μM dose: ca.
Citation
Wang; Mazza
Journal of agricultural and food chemistry, 2002 , vol. 50, # 4 p. 850 - 857 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
RAW 264.7 cell line
Assay Description
Bioassay : in vitro; 6E5 cells/well incubated with title comp. for 24 h; viability of cells determined using MTT assay; DMEM; 37 deg C; 5 percent CO2 atmosphere
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Results
title comp. showed cytotoxicity only at 125 and 500 μmol/l (cell viability: 97 and 20 percent, respectively)
Citation
Wang; Mazza
Journal of agricultural and food chemistry, 2002 , vol. 50, # 4 p. 850 - 857 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : transcriptional factor; modulation of Target : MTLN cells Bioassay : then title comp. added and incubated for further 6 h; luciferase activity determined by luminescence method; PMA: 12-O-tetradecanoyl phorbol-13-acetate; AP-1: activator protein-1 in vitro; effect on AP-1 stimulation evaluated; cells derived from MCF-7 cells stably transfected with luciferase and neomycin resistance gene; 1.25E5 cells/ml; phenol red DMEM with 5 percent FCS; humidified 5 percent CO2; 37 deg C; preincubated for 48 h
Citation
Maggi-Capeyron; Ceballos; Cristol; Delbosc; Le Doucen; Pons; Leger; Descomps
Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 11 p. 5646 - 5652 Title/Abstract Full Text View citing articles Show Details
Effect
Antiallergic
Assay Description
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Target : RBL-2H3 cells Bioassay : washed and suspended in siraganian buffer, pH 7.2; incubated with title comp. for 10 min at 37 deg; then 10 μg/ml DNP-BSA added for 10 min to stimulate degranulation; amount of βhexosaminidase released determined; DNP-BSA: dinitrophenylated BSA in vitro; inhibition of DNP-BSA-induced β-hexosaminidase (degranulation masker of mast cells) release from anti-DNP IgE-sensitized cells evaluated; 2E5 cells/well; MEM with 10 percent FCS; 5 percent CO2; 37 deg C; sensitized overnight with 0.45 μg/ml anti-DNP IgE
Results
at 10/30/100 μmol/l title comp. inhibited β-hexosaminidase release by -4.5/-3.3/-6.5 percent
Citation
Matsuda, Hisashi; Morikawa, Toshio; Tao, Jing; Ueda, Kazuho; Yoshikawa, Masayuki
Chemical and Pharmaceutical Bulletin, 2002 , vol. 50, # 2 p. 208 - 215 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : hydrogen peroxide
Results
scavenging activity <= 59.2 percent
Citation
Cho, Young-Sook; Kim, Se-Kwon; Ahn, Chang-Bum; Je, Jae-Young
Carbohydrate Polymers, 2011 , vol. 83, # 4 p. 1617 - 1622 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : free radical scavenging Target : 2,2-diphenyl-1-picrylhydrazyl radical Bioassay : 2,2-diphenyl-1-picrylhydrazyl radical
Results
scavenging activity <= 49.03 percent
Citation
Cho, Young-Sook; Kim, Se-Kwon; Ahn, Chang-Bum; Je, Jae-Young
Carbohydrate Polymers, 2011 , vol. 83, # 4 p. 1617 - 1622 Title/Abstract Full Text View citing articles Show Details
Effect
Oxidant
Assay Description
Effect : CuI-mediated DNA damage Bioassay : plasmid DNA pBSSK gel electrophoresis
Results
increase rate 11.9 percent
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Citation
Perron, Nathan R.; Garcia, Carla R.; Pinzon, Julio R.; Chaur, Manuel N.; Brumaghim, Julia L.
Journal of Inorganic Biochemistry, 2011 , vol. 105, # 5 p. 745 - 753 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : carbon-centered free radical scavenging Bioassay : AAPH AAPH: 2,2'-azobis(2-amidinopropane).HCl
Results
scavenging capacity 100 percent
Citation
Pasanphan, Wanvimol; Buettner, Garry R.; Chirachanchai, Suwabun
Carbohydrate Research, 2010 , vol. 345, # 1 p. 132 - 140 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : 2,2'-azo-bis(2-amidinopropane) dihydrochloride Triton X-100 used as micelles; oxygen radical absorbance capacity relative to Trolox (ORAC-PGR) = 1
Results
ORAC-PGR oxygen radical absorbance capacity 11.7
Citation
Romero, Max; Rojano, Benjamin; Mella-Raipan, Jaime; Pessoa-Mahana, Carlos David; Lissi, Eduardo; Lopez-Alarcon, Camilo
Molecules, 2010 , vol. 15, # 9 p. 6152 - 6167 Title/Abstract Full Text View citing articles Show Details
Biological material
Caco-2
Assay Description
Effect : transport of fluorescein; examination of Bioassay : permeation rate of fluorescein in the absence (control) and presence of title comp. calculated; relative permation expressed as percentage of value from control study Caco-2 monolayers prepared; solution contain. 0.1 mmol/l fluorescein (pH 6.0, 37 deg C) and title comp. added to apical side of insert; cells incub. at 37 deg C for 40 min; amonut of fluorescein permeated to basolateral side evaluated by fluorescence
Results
relative permeation of fluorescein in test cell monolayers: 109.5 percent of control
Citation
Konishi, Yutaka; Kubo, Kazuo; Shimizu, Makoto
Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 9 p. 2014 - 2017 Title/Abstract Full Text Show Details
Effect
Antiviral
Biological material
human
Assay Description
Effect : anti-viral Species : Human papillomavirus 6/11 Example 4 Drug Screening Through Quantitative Fluorescent PCR Analysis Samples The test compounds listed in Table 1 below were prepared as micro emulsions as described in Example 1. Saline water was used as the control. Methyl 2,3,4-trihydroxybenzoate was prepared as follows: 10 g of 2,3,4-trihydroxybenzoic
Results
no Human papillomavirus HPV 6/11 virus remained 24 hours after treatment with 50 &micro;l micro emulsion containing 10 % of title compound
Citation
QIN, Weihua
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antiviral
Biological material
human
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Assay Description
Effect : anti-viral Species : Human papillomavirus 6/18 Example 4 Drug Screening Through Quantitative Fluorescent PCR Analysis Samples The test compounds listed in Table 1 below were prepared as micro emulsions as described in Example 1. Saline water was used as the control. Methyl 2,3,4-trihydroxybenzoate was prepared as follows: 10 g of 2,3,4-trihydroxybenzoic
Results
no Human papillomavirus HPV 6/18 virus remained 24 hours after treatment with 50 &micro;l micro emulsion containing 10 % off title compound
Citation
QIN, Weihua
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
human
Assay Description
Effect : condyloma acuminata; effect on Example 5 Clinical Use of Hydroxybenzoic Acid Ester in Treating Condyloma Acuminata Diagnosis Standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of Health
Results
treatment with title compound had more apparent treatment effect compared with recombinant human interferon α-2β gel; treatment with title compound showed that in 4 patients more than 70% of skin lesions disappeared after 1-8 days, 4 patients
Citation
QIN, Weihua
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : HBeAg secretion; inhibition of Bioassay : hepatitis B 2.2.15 cells Example 6 Inhibition Effect of Hydroxybenzoic Acid Ester Analogue on Secretion of HBsAg and HBeAg by Hepatitis B 2.2.15 Cell Line Experiment Materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological
Results
treatment with 2 &micro;mol/ml title compound gave an inhibition rate of 9.4%
Citation
QIN, Weihua
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : HBsAg secretion; inhibition of Bioassay : hepatitis B 2.2.15 cells Example 6 Inhibition Effect of Hydroxybenzoic Acid Ester Analogue on Secretion of HBsAg and HBeAg by Hepatitis B 2.2.15 Cell Line Experiment Materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological
Results
treatment with 2 &micro;mol/ml title compound gave an inhibition rate of 8.3%
Citation
QIN, Weihua
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antibiofilm
Biological material
Staphylococcus aureus
Assay Description
Effect : biofilm formation; inhibition of
Results
MBIC90 > 2010 μmol/l
Citation
BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS
Patent: US2012/88671 A1, 2012 ; Title/Abstract Full Text Show Details
Target
Adiponectin:Wild
Assay Description
Effect : adiponectin expression; effect on Bioassay : Example 1: Enhancement of adiponectin expression by (-)-catechin in adipocytesStep 1) Adipocyte DifferentiationMouse 3T3-L1 (ATCC No. CL 173) preadipocyte cells were incubated in DMEM
(Dulbecco's modified Eagle's Medium, Gibco 1210-0038) containing 10% calf serum in 10% CO2 incubator, while
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Citation
LEE, Tae Ryong; BAIK, Joo-Hyun; LEE, Byeong Gon; LEE, Hyoung Ho; CHO, Si Young; SHIN, Dong Wook; KIM, Young-Kyung; PARK, Pil Joon; SHIN, Hyun Jung; SHIN, Euiseok
Patent: WO2007/126293 A1, 2007 ; Title/Abstract Full Text Show Details
Effect
Immunosuppressant
Assay Description
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Results
blocked the granule exocytosis in a dose-dependent manner
Citation
Hamada, Shin-Ichi; Kataoka, Takao; Woo, Je-Tae; Yamada, Atsushi; Yoshida, Takashi; Nishimura, Toshio; Otake, Noboru; Nagai, Kazuo
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 9 p. 1017 - 1019 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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not affects cell viability
Citation
Hamada, Shin-Ichi; Kataoka, Takao; Woo, Je-Tae; Yamada, Atsushi; Yoshida, Takashi; Nishimura, Toshio; Otake, Noboru; Nagai, Kazuo
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 9 p. 1017 - 1019 Title/Abstract Full Text View citing articles Show Details
Effect
Antifungal
Biological material
Cryptococcus neoformans
Bioassay : adaptation of an antifungal bioassay recommended by the National Committee on Clinical Laboratory Standards
Citation
Li; ElSohly; Nimrod; Clark
Planta Medica, 1999 , vol. 65, # 8 p. 780 - 780 Title/Abstract Full Text View citing articles Show Details
Effect
Antiallergic
Biological material
Caco-2
Assay Description
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Target : OE4 cells Bioassay : in vitro; MTT: 3-(4,5-dimethylthiazol-2-yl)2,5-diphenyl tetrazolium bromide assay
Results
Assay Description
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Target : OE4 cells Bioassay : in vitro; granule exocytosis assay; cells preincubated with drug for 2 h; stimulated with immobilized anti-CD3; granzyme A activity in the culture supernatant measured
Bioassay : measurement of inhibitory activity against fluorescein isothiocyanate-labeled ovalbumin permeation through test system monolayers; incubation at 37 deg C for 30 min; fluorescence intensity determination
Results
title comp. showed inhibitory activity at concentration of 10-6 mol/l; graphical representation
Citation
Kobayashi, Shoko; Watanabe, Jun; Fukushi, Eri; Kawabata, Jun; Nakajima, Mitsutoshi; Watanabe, Michiko
Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 6 p. 1250 - 1257 Title/Abstract Full Text View citing articles Show Details
Target
Sulfotransferase 1A1:Wild
Biological material
human thrombocyte
Assay Description
Effect : |enzyme; inhib. of
Bioassay : incubated for 20 min; liquid scintillation counting effect on enzyme activity specific for sulfation of monoamines evaluated; dopamine used as substrate; 6.7 μmol/l <35S>-3'-phosphoadenosine5'-phosphosulfate (spec. act.: 1.0-1.5 Ci/mmol); potassium phosphate buffer, pH 7.0; 37 deg C
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Results
title comp. inhibited enzyme activity by -3.9 percent
Citation
Yeh, Chi-Tai; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2003 , vol. 51, # 5 p. 1474 - 1479 Title/Abstract Full Text View citing articles Show Details
Target
Sulfotransferase 1A1:Wild
Biological material
human thrombocyte
Assay Description
Effect : |enzyme; inhib. of Bioassay : incubated for 20 min; liquid scintillation counting effect on enzyme activity specific for sulfation of small phenols evaluated; p-nitrophenol used as substrate; 6.7 μmol/l <35S>-3'phosphoadenosine-5'-phosphosulfate (spec. act.: 1.0-1.5 Ci/mmol); potassium phosphate buffer, pH 7.0; 37 deg C
Results
title comp. inhibited enzyme activity by -14.0 percent
Citation
Yeh, Chi-Tai; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2003 , vol. 51, # 5 p. 1474 - 1479 Title/Abstract Full Text View citing articles Show Details
Results
weak inhibition of the pollen germination of Camellia japonica at 1000 ppm
Citation
Kobayashi, Satoshi; Ariga, Masato; Ozawa, Tetsuo; Imagawa, Hiroshi
Agricultural and Biological Chemistry, 1984 , vol. 48, # 2 p. 389 - 396 Title/Abstract Full Text Show Details
Assay Description
Effect : |drug interaction Target : rat epididymal adipocytes Bioassay : ratio of 1 indicates no increase in activity effect on isulin activity evaluated; glucose spiked with <U-14C>glucose; Krebs-Ringer phosphate buffer, pH 7.4; room temp.; incubated for 1 h; quantitation of 14CO2 release; insulin enhancing ratio determined
Results
title comp. exhibited insulin enhancing ratio of 1.7
Citation
Anderson, Richard A.; Polansky, Marilyn M.
Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 24 p. 7182 - 7186 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Target : CD-1 (ICR) mouse peritoneal macrophages Bioassay : control: untreated cells; TBARS: thiobarbituric acid reactive substances; TBARS value of control was taken as 100 percent cells were preincubated with title comp. for 4 h in Ham's F-10 medium; washed with PBS; low density lipoprotein added; incubated for 20 h; absorbance measured at 535 nm in UV spectrophotometer; malondialdehyde generated measured by TBARS formation
Results
title comp. pretreatment inhibited macrophage-mediated low density lipoprotein oxidation with TBARS value of 99.3 and 74.7 percent of control at 100 and 400 μmol/l, respectively; table
Citation
Yoshida, Hiroshi; Ishikawa, Toshitsugu; Hosoai, Hiroshi; Suzukawa, Michio; Ayaori, Makoto; Hisada, Tetsuya; Sawada, Shojiro; Yonemura, Atsushi; Higashi, Kenji; Ito, Toshimitsu; Nakajima, Kei; Yamashita, Takeshi; Tomiyasu, Koji; Nishiwaki, Masato; Ohsuzu, Fumitaka; Nakamura, Haruo
Biochemical Pharmacology, 1999 , vol. 58, # 11 p. 1695 - 1703 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
Results
Target : CD-1 (ICR) mouse peritoneal macrophages Bioassay : control: untreated cells cells were preincubated with title comp. for 4 h at 37 deg C in Ham's F-10 medium; lactate dehydrogenase activity measured; washed; incubated with <3H>thymidine for 6 h; <3H>thymidine incorporation into DNA measured; cell viability determined title comp. had no major effect on cell viability; table
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Citation
Yoshida, Hiroshi; Ishikawa, Toshitsugu; Hosoai, Hiroshi; Suzukawa, Michio; Ayaori, Makoto; Hisada, Tetsuya; Sawada, Shojiro; Yonemura, Atsushi; Higashi, Kenji; Ito, Toshimitsu; Nakajima, Kei; Yamashita, Takeshi; Tomiyasu, Koji; Nishiwaki, Masato; Ohsuzu, Fumitaka; Nakamura, Haruo
Biochemical Pharmacology, 1999 , vol. 58, # 11 p. 1695 - 1703 Title/Abstract Full Text View citing articles Show Details
Effect
Cytoprotective
Biological material
Rattus norvegicus liver cell
Assay Description
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Results
title comp.-Fe(3+) complex was much more effective than uncomplexed title comp. at preventing reactive oxygen species-mediated hypoxia-reoxygenation injury in hepatocytes; table
Citation
Moridani, Majid Y.; O'Brien, Peter J.
Biochemical Pharmacology, 2001 , vol. 62, # 12 p. 1579 - 1585 Title/Abstract Full Text View citing articles Show Details
Effect
Oxidant
Assay Description
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title comp. induced peroxide production; effect was slightly inhibited by BAPTA-AM
Citation
Inoue; Sakaguchi; Isuzugawa; Tani; Ogihara
Biological and Pharmaceutical Bulletin, 2000 , vol. 23, # 10 p. 1153 - 1157 Title/Abstract Full Text View citing articles Show Details
Effect
Oxidant
Target : human promyelocytic leukemia HL-60RG cells Bioassay : DCFH-DA: 5,6-carboxy-2',7'-dichlorofluorescin diacetate; further investigations with antioxidant and radical scavengers; NAC: N-acetyl-L-cysteine, antioxidant; SOD: superoxide dismutase; reference comp.: 50 μmol/l H2O2 cells were preloaded with DCFH-DA for 30 min prior to addition of title comp.; intracellular peroxide detected at 0, 5, 10, 20 min after title comp. addition by measuring fluorescence due to oxidation of DCFH-DA
Results
title comp. induced time-dependent peroxide production; effect was suppressed by NAC, ascorbic acid, SOD/catalase and slightly by catalase; H2O2-induced peroxide generation suppressed by SOD/catalase and catalase and not by NAC and ascorbate
Citation
Inoue; Sakaguchi; Isuzugawa; Tani; Ogihara
Biological and Pharmaceutical Bulletin, 2000 , vol. 23, # 10 p. 1153 - 1157 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Assay Description
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Target : human promyelocytic leukemia HL-60RG cells Bioassay : DCFH-DA: 5,6-carboxy-2',7'-dichlorofluorescin diacetate; BAPTA-AM: intracellular Ca(2+) chelator cells were preloaded with DCFH-DA in combination with BAPTA-AM for 30 min prior to title comp. addition; intracellular peroxide level detected at 5 min after title comp. addition by measuring fluorescence due to DCFH-DA oxidation
Results
Assay Description
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Bioassay : hepatocytes incubated with title comp. or its Fe(3+) complex under an atmosphere of 95 percent N2 and 5 percent CO2 for 90 min; before re-oxygenation with 1 percent O2, 94 percent N2 and 5 percent CO2, viability of cells determined by trypan blue exclusion
Target : Salmonella typhimurium TA102 Bioassay : bacterial culture in agar was incubated with title comp. alone or in presence of bleomycin; toxic effect of title comp. to test system assessed
Citation
Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Assay Description
Target : Salmonella typhimurium TA102 Bioassay : bacterial culture in agar was incubated with title comp. alone or in presence of H2O2; toxic effect of title comp. to test system assessed
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Citation
Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
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Citation
Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
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Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details
Effect
Mutagenic
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Target : Salmonella typhimurium TA102 Bioassay : bacterial culture in agar incubated with title comp. for 48 h at 37 deg C; number of histidine revertant colonies counted microscopically; mutagenic effect of title comp. determined
Citation
Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Target : Salmonella typhimurium TA102 Bioassay : positive control: without title comp. bacterial culture in agar incubated with title comp. in presence of H2O2 for 48 h at 37 deg C; number of histidine revertant colonies counted microscopically; inhibition of bleomycin- and H2O2-induced mutagenicity determined
Citation
Assay Description
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Target : Salmonella typhimurium TA102 Bioassay : positive control: without title comp. bacterial culture in agar incubated with title comp. in presence of bleomycin for 48 h at 37 deg C; number of histidine revertant colonies counted microscopically; inhibition of bleomycin- and H2O2-induced mutagenicity determined
Target : microglial BV2 cells of mouse Bioassay : cells in DMEM were treated with title comp. for 1 h and then stimulated with 1 ng/ml lipopolysaccharide (LPS); after 24 h of incubation cell viability assayed by 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide (MTT) assay
Citation
Mi, Kyeong Lee; Hee, Young Jeon; Ki, Yong Lee; Seung, Hyun Kim; Choong, Je Ma; Sang, Hyun Sung; Lee, Heum-Sook; Mi, Jung Park; Young, Choong Kim
Planta Medica, 2007 , vol. 73, # 8 p. 782 - 786 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : mutation rate; effect on Target : Salmonella typhimurium TA102 Bioassay : control: vehicle; reference comp.: benzidine and hydrogen peroxide reaction mixture included 100 μl of overnight bacterial culture, 100 μl of title comp. solution, and no or 500 μl of rat liver S9 mix; after incubation mixture was plated in minimal agar; 48 h later revertant colonies were counted
Citation
Makena, Patrudu S.; Chung, King-Thom
Food and Chemical Toxicology, 2007 , vol. 45, # 10 p. 1899 - 1909 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Target : Salmonella typhimurium TA102 Bioassay : controls: dimethyl sulfoxide (DMSO) alone or benzidine alone 100 μl of benzidine was added to 100 μl of overnight bacterial culture in presence or absence of 500 μl of rat liver S9 mix; incubation with 100 μl title comp.; plating in minimal agar; 48 h later revertant colonies were counted
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Results
50, 100, and 200 μg/plate title comp. reduced number of revertants/plate in presence of S9 from 1049 in benzidine control to 483, 393, and 287, resp., compared to 325 in DMSO control; title comp. also reduced number of revertants in absence of S9;
Citation
Makena, Patrudu S.; Chung, King-Thom
Food and Chemical Toxicology, 2007 , vol. 45, # 10 p. 1899 - 1909 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Target : Salmonella typhimurium TA102 Bioassay : control: vehicle; reference comp.: benzidine and hydrogen peroxide reaction mixture consisted of 100 μl overnight bacterial culture, 100 μl of title comp. solution, and no or 500 μl of rat liver S9 mix; incubation for 4 h; then trypan blue dye was added and viable or dead cell were counted using hemocytometer
Citation
Makena, Patrudu S.; Chung, King-Thom
Food and Chemical Toxicology, 2007 , vol. 45, # 10 p. 1899 - 1909 Title/Abstract Full Text View citing articles Show Details
Biological material
RAW 264.7 cell line
Assay Description
Effect : NO production; inhibition of Bioassay : inhibition ( percent): (1-((title comp. data) - (negative control data))/((positive control data) - (negative control data)*100 percent; LPS: lipopolysaccharide: IFN-γ: interferon-γ LPS/IFN-γstimulated test cells incubated with title comp.; level of extracelluar NO measured using Griess mod
Citation
Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details
Biological material
RAW 264.7 cell line
Assay Description
Effect : peroxide anion production; inhibition of Bioassay : inhibition ( percent): (1-((title comp. data) - (negative control data))/((positive control data) - (negative control data)*100 percent; LPS: lipopolysaccharide: IFN-γ: interferon-γ LPS/IFN-γstimulated test cells incubated with title comp.; level of extracelluar O2(1-) measured using cytochrome c reduction method
Results
inhibition 30.9 percent
Citation
Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details
Biological material
RAW 264.7 cell line
Assay Description
Effect : peroxinitrite anion production; inhibition of Bioassay : inhibition ( percent): (1-((title comp. data) - (negative control data))/((positive control data) - (negative control data)*100 percent; LPS: lipopolysaccharide: IFN-γ: interferon-γ LPS/IFN-γstimulated test cells incubated with title comp.; level of extracelluar ONOO(1-) measured using dehydrorhodamine 123 method
Results
inhibition 9.3 percent
Citation
Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details
Biological material
RAW 264.7 cell line
Assay Description
Effect : RONS production; inhibition of Bioassay : RONS: reactive oxygen and nitrogen species; AS52 cells: Chinese hamster ovary AS52 cells; LPS: lipopolysaccharide: IFN-γ: interferon-γ 5E5 test cells co-cultured with AS52 cells at ratio 1:1, incubated with 100 ng/ml LPS, 100 U/ml IFN-γ and title comp. for 24 h; test cell generated RONS induced mutation inhibition in AS52 cells investigated
Results
mutation inhibition 54.7 percent
Citation
Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details
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Effect
Cytotoxic
Biological material
RAW 264.7 cell line
Assay Description
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Results
cell viability 87.5 percent
Citation
Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human HL-60 cell line
Assay Description
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Bioassay : LPS: lipopolysaccharide: IFN-γ: interferon-γ LPS/IFN-γ-stimulated test cells incubated with title comp.; cell viability investigated
Bioassay : 1E6 cells incubated with title comp. at 37 deg C for 15 min, incubated with 100 nmol/l 12-O-tetradecanoylphorbol-13-acetate for 15 min
Results
cell viability 79.3 percent
Citation
Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details
Biological material
human HL-60 cell line
Assay Description
Effect : peroxide anion production; inhibition of Bioassay : inhibition ( percent): (1-((title comp. data) - (negative control data))/((positive control data) - (negative control data)*100 percent 1E6 cells incubated with title comp. at 37 deg C for 15 min, incubated with 100 nmol/l 12-O-tetradecanoylphorbol-13-acetate for 15 min; level of extracelluar O2(1-) measured using cytochrome c reduction method
Results
inhibition 27.2 percent
Citation
Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details
Biological material
human HL-60 cell line
Assay Description
Effect : RONS production; inhibition of Bioassay : RONS: reactive oxygen and nitrogen species; AS52 cells: Chinese hamster ovary AS52 cells 5E5 test cells co-cultured with AS52 cells at ratio 1:1, incubated with title comp. and 100 nmol/l 12O-tetradecanoylphorbol-13-acetate for 1 h; test cell generated RONS induced mutation inhibition in AS52 cells investigated
Results
mutation inhibition 35.4 percent
Citation
Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details
Target
Transcription factor AP-1:Wild
Biological material
human HT-29
Assay Description
Effect : AP-1 transcriptional activity; effect on Bioassay : EGCG: (-)-epigallocatecin-3-gallate; AP-1: activator protein-1; dietary antioxidants AP-1 promoter/luciferase and control vectors transfected into cells; pretreated with title comp. for 30 min; exposed to EGCG or vehicle for 1 h; washed; incubated with title comp. for 17 h; harvested; AP-1 activity assayed
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Results
inhibited EGCG-upregulated AP-1 transcription activity by 77% (diagram)
Citation
Kim, Mihye; Murakami, Akira; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 10 p. 2442 - 2450 Title/Abstract Full Text View citing articles Show Details
Biological material
human HT-29
Assay Description
Effect : mRNA expression; effect on Bioassay : EGCG: (-)-epigallocatecin-3-gallate; MMP-7: matrix metalloprotease-7; GAPDH: glyceraldehyde-3-phosphate-dehydrogenase; vehicle-treated (6 h) cells expressed MMP7 mRNA at low level; EGCG upregulated MMP7 expression by 2.7 fold cells pretreated with vehicle or title comp. for 30 min; exposed to EGCG or vehicle for 1 h; washed; incubated in serum-free DMEM for 5 h; harvested; total RNA extracted; reverse transcriptase-polymerase chain reaction; GAPDH as internal control
Results
no effect on MMP-7 mRNA expression compared with vehicle; signif. suppressed EGCG-upregulated MMP-7 mRNA expression (diagram)
Citation
Kim, Mihye; Murakami, Akira; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 10 p. 2442 - 2450 Title/Abstract Full Text View citing articles Show Details
Biological material
human HT-29
Assay Description
Effect : pro-matrix metalloproteinase production; effect on Bioassay : EGCG: (-)-epigallocatecin-3-gallate; proMMP-7: pro-matrix metalloprotease-7; dietary antioxidants; 25 μM of EGCG enhanced production of intracellular proMMP-7 protein by 6-fold cells pretreated with title comp. or DMSO for 30 min; exposed to EGCG or vehicle for 1 h; cells washed with PBS; incubated in serum-free DMEM for 23 h; Western blotting; DMSO as negative control
Results
reduced EGGG-enhanced proMMP-7 production; no effect on spontaneous proMMP-7 production (diagram); similar effect for extracellular proMMP-7 protein
Citation
Kim, Mihye; Murakami, Akira; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 10 p. 2442 - 2450 Title/Abstract Full Text View citing articles Show Details
Biological material
human HT-29
Assay Description
Effect : H2O2 production; effect on Bioassay : EGCG: (-)-epigallocatecin-3-gallate; dietary antioxidants; spontaneous and EGCG-induced H2O2 generation cells pretreated with title comp. for 30 min; exposed to EGCG or vehicle for 30 min; harvested; H2O2 conc. determined by ferrous ion-oxidation-xylenol orange method; visible absorption at 550 nm measured
Citation
Kim, Mihye; Murakami, Akira; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 10 p. 2442 - 2450 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Assay Description
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Bioassay : positive control: maleic hydrazide; negative control: aerated Hoagland's solution secondary roots of test system exposed to title comp. for 6 h; after 24 h of recovery, root tips were fixed overnight in Carnoy's solution at 4 deg C; hydrolyzed; slides prepared; stained; frequencies of micronucleus scored; mitotic index calculated
Results
title comp. treatment resulted in mitotic index ranging between 2 and 17%; title comp. induced a strong increase in micronucleus frequency, 7.5-fold above negative control and not significantly different from positive control; fig.
Citation
El Hajjouji; Pinelli; Guiresse; Merlina; Revel; Hafidi
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2007 , vol. 634, # 1-2 p. 25 - 31 Title/Abstract Full Text View citing articles Show Details
Effect
Antiviral
Biological material
Chlorocebus aethiops VERO
Assay Description
Effect : plaque formation Target : HSV-1 cell monolayer tested; HSV: herpes simplex virus
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Citation
Tian, Li-Wen; Zhang, Ying-Jun; Qu, Chang; Wang, Yi-Fei; Yang, Chong-Ren
Journal of Natural Products, 2010 , vol. 73, # 2 p. 160 - 163 Title/Abstract Full Text View citing articles Show Details
Biological material
Caenorhabditis elegans
Assay Description
Effect : lifespan Bioassay : L4 larva no significant lifespan change at 300 μmol/l was foundin presence of dead bacteria;
Results
mean lifespan change rate 105 - 111.73 percent
Citation
Saul, Nadine; Pietsch, Kerstin; Stuerzenbaum, Stephen R.; Menzel, Ralph; Steinberg, Christian E. W.
Journal of Natural Products, 2011 , vol. 74, # 8 p. 1713 - 1720 Title/Abstract Full Text View citing articles Show Details
Biological material
Caenorhabditis elegans
Assay Description
Effect : lifespan Species : Caenorhabditis elegans eat-2(ad465) Bioassay : L4 larva
Citation
Saul, Nadine; Pietsch, Kerstin; Stuerzenbaum, Stephen R.; Menzel, Ralph; Steinberg, Christian E. W.
Journal of Natural Products, 2011 , vol. 74, # 8 p. 1713 - 1720 Title/Abstract Full Text View citing articles Show Details
Biological material
Caenorhabditis elegans
Assay Description
Effect : lifespan Species : Caenorhabditis elegans mev-1(kn-1) Bioassay : L4 larva
Results
mean lifespan change rate 106.76 percent
Citation
Saul, Nadine; Pietsch, Kerstin; Stuerzenbaum, Stephen R.; Menzel, Ralph; Steinberg, Christian E. W.
Journal of Natural Products, 2011 , vol. 74, # 8 p. 1713 - 1720 Title/Abstract Full Text View citing articles Show Details
Target
Aldose reductase:Wild + Aldose reductase [human]:Wild
Biological material
human
Assay Description
Effect : enzyme activity diabetes complications Bioassay : recombinant aldose reductase spectrophotometric assay
Citation
Lee, Yeon Sil; Kim, Jin Kyu; Bae, Young Soo; Won, Moo-Ho; Kang, Il-Jun; Lim, Soon Sung
Archives of Pharmacal Research, 2011 , vol. 34, # 2 p. 211 - 215 Title/Abstract Full Text View citing articles Show Details
Target
Aminopeptidase N:Wild
Assay Description
Effect : enzyme activity Bioassay : aminopeptidase N
Citation
Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details
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Effect
Antiinflammatory
Biological material
human neutrophil
Assay Description
Effect : LPS-stimulated IL-8 release LPS: lipopolysacharide; IL-8: interleukin-8; ELISA
Citation
Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details
Effect
Antiinflammatory
Biological material
human neutrophil
Assay Description
Effect : f-MLP and cytochalasin B-stimulated LTB4 release f-MLP: formyl-Met-Leu-phenylalanine; LTB4: leukotriene B4; ELISA
Citation
Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details
Effect
Antiinflammatory
Biological material
human neutrophil
Assay Description
Effect : f-MLP-stimulated elastase release f-MLP: formyl-Met-Leu-phenylalanine; spectrophotometric assay
Citation
Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Biological material
Salmonella enterica serovar Typhimurium
Assay Description
Effect : his+ revertants/plate Bioassay : incubation at 37 deg C; title comp. and mutagen were dissolved in DMSO; NPD as positive control (considered as 100 percent mutagenicity); his+ revertants counted Ames assay (plate incorporation test); co-incubation and pre-incubation procedures; effect of title comp. against 2-aminofluorene (2-AF)-induced mutagenicity
Results
moderate dose-dependent inhibitory effect, being not more than 50 percent, more expressed at pre-incubation assay
Citation
Kaur, Simran; Grover; Singh, Majar; Kaur, Satwinderjeet
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 1998 , vol. 419, # 1-3 p. 169 - 179 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Biological material
Salmonella enterica serovar Typhimurium
Assay Description
Effect : his+ revertants/plate Bioassay : incubation at 37 deg C; title comp. and mutagen were dissolved in DMSO; NPD as positive control (considered as 100 percent mutagenicity); his+ revertants counted Ames assay (plate incorporation test); co-incubation and pre-incubation procedures; effect of title comp. against 4-nitro-o-phenylenediamine (NPD)-induced mutagenicity
Results
unsignificant dose-dependent inhibitory effect, more expressed at co-incubation assay
Citation
Kaur, Simran; Grover; Singh, Majar; Kaur, Satwinderjeet
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 1998 , vol. 419, # 1-3 p. 169 - 179 Title/Abstract Full Text View citing articles Show Details
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Effect
Antimutagenic
Biological material
Salmonella enterica serovar Typhimurium
Assay Description
Effect : his+ revertants/plate Bioassay : incubation at 37 deg C; 4-NQNO as positive control (considered as 100 percent mutagenicity); his+ revertants counted Ames assay (plate incorporation test); effect of title comp. against 4nitroquinoline-N-oxide (4-NQNO)-induced mutagenicity
Citation
Kaur, Simran; Grover; Singh, Majar; Kaur, Satwinderjeet
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 1998 , vol. 419, # 1-3 p. 169 - 179 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
Effect : acute cells death Target : Fischer-344 rats Bioassay : rats 260-290 g mass; incubation in Krebs-Henseleit buffer; 37 deg C; pH 7.4; vehicle, DMSO; hepatocytes 1E6 cells/ml; incubation time, 30, 60 and 90 min liver hepatocytes isolated; biochemical assay; conc. protein determination; HPLC technique
Results
caused cell death 25 percent (control 23 percent) after 3 h; concentration-dependent cell death, losses of cellular GSH and protein thiol levels; appearance of cell blebbing; abrupt depletion of ATP and adenine nucleotides pool
Citation
Nakagawa; Tayama
Archives of Toxicology, 1995 , vol. 69, # 3 p. 204 - 208 Title/Abstract Full Text Show Details
Effect
Cytotoxic
Assay Description
Effect : mitochondria dysfunction Target : Fischer-344 rats Bioassay : mitochondria 1 mg protein/ml; respiration buffer; 25 deg C; pH 7.4; in presence and exhaustion of ADP, 20 μM mitochondria isolated; rate oxygen consumption measurement
Results
concentration-dependent increase in rate of state 4 oxygen consumption; uncoupling effect of oxidative phosphorylation in mitochondria; respiratory control index 4.4-3.8 (control 4.4)
Citation
Nakagawa; Tayama
Archives of Toxicology, 1995 , vol. 69, # 3 p. 204 - 208 Title/Abstract Full Text Show Details
Effect
Phytotoxic
Assay Description
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Target : Zea mays L., maize inbred Mp313E x SC212M hybrid Bioassay : milk-stage kernels; water solution; 18 kernels punctured through the pericarp in vitro
Results
browning of pericarp after 4 and 24-hr (mm): 1.2+/-0.7, 1.8+/-0.9; controls: 0.1+/-0.3 and 0.7+/-0.3, respectively
Citation
Dowd, Patrick
Journal of Chemical Ecology, 1994 , vol. 20, # 11 p. 2777 - 2804 Title/Abstract Full Text View citing articles Show Details
Effect
Phytotoxic
Assay Description
Target : Zea mays L., maize inbred Mp313E Bioassay : milk-stage kernels; water solution; 18 kernels punctured through the pericarp in vitro
Results
browning of pericarp after 4 and 24-hr (mm): 1.5+/-0.7, 2.9+/-0.7; controls: 0.5+/-0.2 and 1.2+/-0.5, respectively
Citation
Dowd, Patrick
Journal of Chemical Ecology, 1994 , vol. 20, # 11 p. 2777 - 2804 Title/Abstract Full Text View citing articles Show Details
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Effect Assay Description
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Phytotoxic
Target : Zea mays L., maize inbred SC212M Bioassay : milk-stage kernels; water solution; 18 kernels punctured through the pericarp in vitro
Results
browning of pericarp after 4 and 24-hr (mm): 0.2+/-0.3, 0.6+/-0.2; controls: 0.0+/-0.0 and 0.4+/-0.2, respectively
Citation
Dowd, Patrick
Journal of Chemical Ecology, 1994 , vol. 20, # 11 p. 2777 - 2804 Title/Abstract Full Text View citing articles Show Details
Results
antioxidative activity in β-carotene aqueous model system, at 50E-5percent 1.06; at 1E-5M 1.05 relative antioxidative activity
Citation
Ariga, Toshiaki; Koshiyama, Ikunori; Fukushima, Danji
Agricultural and Biological Chemistry, 1988 , vol. 52, # 11 p. 2717 - 2722 Title/Abstract Full Text Show Details
Results
no coenzymatic activity for vitamin B2-aldehyde forming enzyme
Citation
Oka, Masanori; Tachibana, Sei
Agricultural and Biological Chemistry, 1984 , vol. 48, # 11 p. 2893 - 2896 Title/Abstract Full Text Show Details
Results
inhibition effect of rat small intestinal sucrase and α-glucosidase activities
Citation
Honda, Miwa; Hara, Yukihiko
Bioscience, Biotechnology, and Biochemistry, 1993 , vol. 57, # 1 p. 123 - 124 Title/Abstract Full Text Show Details
Results
no inhibitory effect on crude rat lens aldose reductase
Citation
Shimizu; Horie; Terashima; Ueno; Hayashi; Arisawa; Suzuki; Yoshizaki; Morita
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2531 - 2532 Title/Abstract Full Text View citing articles Show Details
Results
growth inhibition of mutants 3937 cbs29, 3937 fct18 and 3937 fct34 acsA12 of bacterium Erwinia chrysanthemi
Citation
Mila, Isabelle; Scalbert, Augustin; Expert, Dominique
Phytochemistry, 1996 , vol. 42, # 6 p. 1551 - 1555 Title/Abstract Full Text View citing articles Show Details
Results
radical scavenging activity; antioxidative activity in the rabbit erythrocyte membrane ghost system; suppressive effect on pentosidine formation
Citation
Oya; Osawa; Kawakishi
Bioscience, Biotechnology and Biochemistry, 1997 , vol. 61, # 2 p. 263 - 266 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
Target : cells of digestive gland of Unio tumidus, fresh-water mussel Bioassay : control: no treatment cells treated with title comp. for 1 h at 5 deg C; trypan-blue dye exclusion assay performed
Results
title comp. dose-dependently reduced viability; fig.
Citation
Labieniec, Magdalena; Gabryelak, Teresa
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 603, # 1 p. 48 - 55
Title/Abstract Full Text View citing articles Show Details
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Effect Assay Description
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title comp. induced DNA damage, effect enhanced after FPG or proteinase K treatment; fig.
Citation
Labieniec, Magdalena; Gabryelak, Teresa
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 603, # 1 p. 48 - 55 Title/Abstract Full Text View citing articles Show Details
Effect
Oxidant
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Target : cells of digestive gland of Unio tumidus, fresh-water mussel Bioassay : control: no treatment cells treated with title comp. for 1 h at 5 deg C; Ellman's reagent added, thiol groups det. spectrophotometrically at 412 nm
Results
15-60 μM title comp. dose-dependently reduced thiol group content; fig.
Citation
Labieniec, Magdalena; Gabryelak, Teresa
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 603, # 1 p. 48 - 55 Title/Abstract Full Text View citing articles Show Details
Effect
Toxic
Biological material
HL-60 cell line
Assay Description
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Target : cells of digestive gland of Unio tumidus, fresh-water mussel Bioassay : control: no treatment (buffer) cells treated with title comp. for 30 min at 37 deg C followed by FPG post-treatment or proteinase K (2 h) treatment; comet assay at pH 13
Results
Assay Description
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Genotoxic
Bioassay : cells incubated with title comp. for 48 h; XTT-PMS solution added to each well; after incubating for 4 h at 37 deg C absorbance measured
Citation
Agnihotri, Vijai K.; ElSohly, Hala N.; Khan, Shabana I.; Smillie, Troy J.; Khan, Ikhlas A.; Walker, Larry A.
Phytochemistry, 2008 , vol. 69, # 10 p. 2061 - 2066 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : hydrogen peroxide production; effect on Target : colon adenoma LT97 cells of human Bioassay : control: without title comp.; further study: addition of catalase on title comp. effect cells incubated with title comp. at 37 deg C for 10 to 180 min; FOX2 reagent added; incubated at 30 min at room temperature; centrifuged; supernatant collected; absorbance measured at 550 nm
Results
title comp. was less effective, signif. hydrogen peroxide production were detected for 88 μM after 10 min of incubation; addition of catalase reduced signal to zero which indicates which indicates title comp. treatment in H202 formation; fig.
Citation
Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : hydrogen peroxide production; effect on Target : colon adenoma LT97 cells of human Bioassay : control: without title comp. cells incubated with title comp. at 37 deg C up to 1 h; FOX2 reagent added; incubated at 30 min at room temperature; centrifuged; supernatant collected; absorbance measured at 550 nm;
Citation
Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |metabolic Target : colon adenoma LT97 cells of human Bioassay : control: untreated cells cells incubated with title comp. for 24 to 72 h; CellTitre-Blue TM added 2 h before the end of incubation period; fluorescence activity measured (excitation at 520
nm/emission at 595 nm); metabolic activity detd.
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Citation
Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Biological material
HT-29
Assay Description
Effect : hydrogen peroxide production; effect on Bioassay : control: without title comp.; further study: addition of catalase on title comp. effect cells incubated with title comp. at 37 deg C for 10 to 180 min; FOX2 reagent added; incubated at 30 min at room temperature; centrifuged; supernatant collected; absorbance measured at 550 nm
Results
title comp. was less effective, signif. hydrogen peroxide production were detected for 88 μM after 10 min of incubation; addition of catalase reduced signal to zero which indicates which indicates title comp. treatment in H202 formation; fig.
Citation
Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Biological material
HT-29
Assay Description
Effect : hydrogen peroxide production; effect on Bioassay : control: without title comp. cells incubated with title comp. at 37 deg C for up to 1 h; FOX2 reagent added; incubated at 30 min at room temperature; centrifuged; supernatant collected; absorbance measured at 550 nm
Citation
Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Biological material
HT-29
Assay Description
Effect : |metabolic Bioassay : control: untreated cells cells incubated with title comp. for 12 to 72 h; CellTitre-Blue TM added 2 h before the end of incubation period; fluorescence activity measured (excitation at 520 nm/emission at 595 nm); metabolic activity detd.
Citation
Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Effect
Antiproliferative
Assay Description
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Target : colon adenoma LT97 cells of human Bioassay : control: without title comp. cells incubated with title comp. for 12 to 72 h; 2 h before the end of post treatment, 10 μl5-bromo-2-deoxyuridine added; DNA-synthesis detd. using chemiluminescence
Citation
Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Effect
Antiproliferative
Biological material
HT-29
Assay Description
Citation
Bioassay : control: without title comp. cells incubated with title comp. for 12 to 72 h; 2 h before the end of post treatment, 10 μl5-bromo-2-deoxyuridine added; DNA-synthesis detd. using chemiluminescence Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
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Effect Assay Description
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Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
HT-29
Bioassay : control: without title comp. cells incubated with title comp. for 12 to 72 h; amount of DNA which is related to the number of cells detd.
Citation
Klenow; Glei; Haber; Owen; Pool-Zobel
Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : immobilized enzyme assay system; incubation with 18 mM/l maltose and title comp. for 30 min at 37 deg C; maltase activity determined by measuring glucose liberated from maltose by Glucose F-kit; data are presented as Inhibitory ratio under fixed conc.
Results
Inhibitory ratio:71.0 percent
Citation
Matsui, Toshiro; Ebuchi, Sumi; Fukui, Keiichi; Matsugano, Kazusato; Terahara, Norihiko; Matsumoto, Kiyoshi
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 11 p. 2239 - 2246 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : immobilized enzyme assay system; incubation with 8 mM/l sucrose and title comp. for 30 min at 37 deg C; sucrase activity determined by measuring glucose liberated from maltose by Glucose F-kit; data are presented as Inhibitory ratio under fixed conc.
Results
Inhibitory ratio:9.7 percent
Citation
Matsui, Toshiro; Ebuchi, Sumi; Fukui, Keiichi; Matsugano, Kazusato; Terahara, Norihiko; Matsumoto, Kiyoshi
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 11 p. 2239 - 2246 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Target : colon adenoma LT97 cells of human Bioassay : control: without title comp. cells incubated with title comp. for 24 to 72 h; amount of DNA which is related to the number of cells detd.
Citation
Assay Description
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Cytotoxic
Target : WB-F344 rat liver epithelial cells Bioassay : DMEM with 10 percent FBS; humidified 5 percentCO2/95 percent air; 37 deg C; incubated for 48 h without or with bovine liver catalase (100 Sigma units/ml); 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide colorimetric assay
Results
title comp. inhibited cell proliferation in conc.-dependent manner at 12.5 μg/ml and more and exhibited cytotoxicity of 54 percent at 25 μg/ml; title comp. cytotoxicity was in part abolished by addition of catalase
Citation
Ki, Won Lee; Haeng, Jeon Hur; Hyong, Joo Lee; Chang, Yong Lee
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 6 p. 1990 - 1995 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Results
title comp. produced complete inhibition of GJIC and this effect was in part abolished by addition of catalase
Citation
Ki, Won Lee; Haeng, Jeon Hur; Hyong, Joo Lee; Chang, Yong Lee
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 6 p. 1990 - 1995 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human Caco-2
Assay Description
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Target : WB-F344 rat liver epithelial cells Bioassay : effect on gap-junction intercellular communication (GJIC) evaluated by scrape loading/dye-transfer method; DMEM with 10 percent FBS; humidified 5 percentCO2/95 percent air; 37 deg C; incubated for 1 h without or with bovine liver catalase (100 Sigma units)
Bioassay : DMEM with 10 percent FBS; humidified 5 percentCO2/95 percent air; 37 deg C; incubated for 48 h without or with bovine liver catalase (100 Sigma units/ml); 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide colorimetric assay
Results
title comp. inhibited cell proliferation in conc.-dependent manner at 12.5 μg/ml and more and exhibited cytotoxicity of 75 percent at 25 μg/ml; title comp. cytotoxicity was in part abolished by addition of catalase
Citation
Ki, Won Lee; Haeng, Jeon Hur; Hyong, Joo Lee; Chang, Yong Lee
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 6 p. 1990 - 1995 Title/Abstract Full Text View citing articles Show Details
Biological material
PC12
Assay Description
Effect : H2O2-induced mitochondrial depolarization flow cytometry; PC12: rat pheochromocytoma cell line
Citation
Crispo, James A.G.; Piche, Matthew; Ansell, Dominique R.; Eibl, Joseph K.; Tai, Isabella T.; Kumar, Aseem; Ross, Gregory M.; Tai
Biochemical and Biophysical Research Communications, 2010 , vol. 393, # 4 p. 773 - 778 Title/Abstract Full Text View citing articles Show Details
Target
Sucrose phosphorylase:Wild
Biological material
Leuconostoc mesenteroides
Assay Description
Effect : transglucosylation activity enzyme activity Species : Leuconostoc mesenteroides ATTC 12291 Bioassay : sucrose phosphorylase LmSP2: L. mesenteroides ATTC 12291 sucrose phosphorylase; hydrolysis rate determined as reference to water hydrolysis; bicinchoninic acid assay
Results
hydrolysis rate 0.65
Citation
Aerts, Dirk; Verhaeghe, Tom F.; Roman, Bart I.; Stevens, Christian V.; Desmet, Tom; Soetaert, Wim
Carbohydrate Research, 2011 , vol. 346, # 13 p. 1860 - 1867 Title/Abstract Full Text View citing articles Show Details
Target
Sucrose phosphorylase:Wild
Biological material
Leuconostoc mesenteroides
Assay Description
Effect : transglucosylation activity enzyme activity Species : Leuconostoc mesenteroides NRRL B1355 Bioassay : sucrose phosphorylase LmSP3: L. mesenteroides NRRL B1355 sucrose phosphorylase; hydrolysis rate determined as reference to water hydrolysis; bicinchoninic acid assay
Results
hydrolysis rate 0.3
Citation
Aerts, Dirk; Verhaeghe, Tom F.; Roman, Bart I.; Stevens, Christian V.; Desmet, Tom; Soetaert, Wim
Carbohydrate Research, 2011 , vol. 346, # 13 p. 1860 - 1867
Title/Abstract Full Text View citing articles Show Details
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Biological material
Lactobacillus acidophilus
Assay Description
Effect : transglucosylation activity enzyme activity Target : LaSP Bioassay : sucrose phosphorylase LaSP: L. acidophilus LMG 9433 sucrose phosphorylase; hydrolysis rate determined as reference to water hydrolysis; bicinchoninic acid assay
Results
hydrolysis rate 0.18
Citation
Aerts, Dirk; Verhaeghe, Tom F.; Roman, Bart I.; Stevens, Christian V.; Desmet, Tom; Soetaert, Wim
Carbohydrate Research, 2011 , vol. 346, # 13 p. 1860 - 1867 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : scavenging activity Bioassay : DPPH radical DPPH: 2,2-diphenyl-1-picrylhydrazyl
Results
ARP anti-radical power 12.5
Citation
Arteaga, Jesus F; Ruiz-Montoya, Mercedes; Palma, Alberto; Alonso-Garrido, Gema; Pintado, Sara; Rodriguez-Mellado, Jose M
Molecules (Basel, Switzerland), 2012 , vol. 17, # 5 p. 5126 - 5138 Title/Abstract Full Text Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : 1,1-diphenyl-2-picrylhydrazyl
Results
SC50 radical-scavenging activity 10.7 μmol/l
Citation
She, Gai-Mei; Zhang, Ying-Jun; Yang, Chong-Ren
Chemistry and Biodiversity, 2009 , vol. 6, # 6 p. 875 - 880 Title/Abstract Full Text View citing articles Show Details
Effect
Anticoagulant
Biological material
human
Assay Description
Effect : anticoagulant Bioassay : plasma
Citation
Correia-Da-Silva, Marta; Sousa, Emilia; Duarte, Barbara; Marques, Franklim; Cunha-Ribeiro, Luis M.; Pinto, Madalena M.M.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2347 - 2358 Title/Abstract Full Text View citing articles Show Details
Target
Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : in vitro
Results
title comp. inhibited enzyme activity by 33.0 percent
Citation
Wenzhe, Fan; Tezuka, Yasuhiro; Kadota, Shigetoshi
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 7 p. 1055 - 1061 Title/Abstract Full Text View citing articles Show Details
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Results
no activity against Escherichia Coli B and B. stearothermophilis ATCC 12980
Citation
Serit, Muney; Okubo, Tsutomu; Su, Rong-Hui; Hagiwara, Nobuyuki; Kim, Mujo; et al.
Agricultural and Biological Chemistry, 1991 , vol. 55, # 1 p. 19 - 23 Title/Abstract Full Text Show Details
Results
antibacterial activity: Bacillus subtilis, MIC=71.3 μg/ml; Staphylococcus aureus, MIC=71.3 μg/ml
Citation
Majinda, Runner R. T.; Motswaledi, Modisa; Waigh, Roger D.; Waterman, Peter G.
Planta Medica, 1997 , vol. 63, # 3 p. 268 - 270 Title/Abstract Full Text View citing articles Show Details
Biological material
Mus musculus 3T3-L1 cell line
Assay Description
Effect : adiponectin expression; effect on Bioassay : 3T3-L1 differentiated adipocytes Example 1: Enhancement of adiponectin expression by (-)-catechin in adipocytesStep 1) Adipocyte DifferentiationMouse 3T3-L1 (ATCC No. CL 173) preadipocyte cells were incubated in DMEM (Dulbecco's modified Eagle's Medium, Gibco 1210-0038) containing 10% calf serum in 10% CO2 incubator, while
Citation
CHO, Si Young; PARK, Pil Joon; SHIN, Hyun Jung; KIM, Young-Kyung; SHIN, Dong Wook; SHIN, Euiseok; LEE, Hyoung Ho; LEE, Byeong Gon; BAIK, Joo-Hyun; LEE, Tae Ryong
Patent: WO2007/126293 A1, 2007 ; Title/Abstract Full Text Show Details
Assay Description
Effect : the growth of Gardnerella vaginalis; inhibiion of Target : ATCC #14018 of Gardnerella vaginalis Bioassay : The ability of the vaginal treatment composition of the present invention to inhibit and/or treat vaginal infection was demonstrated. Initially, eight (8) solutions were formed as set forth below in Table 8. Samples 1-2 were prepared by dissolving the KELCOGEL&reg; (0.07 grams) and/or xylitol (0.44
Results
The test compound exhibited inhibition for Gardnerella vaginalis growth, average plate count - 3.43 &times; 104 .
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2006/105963 A1, 2006 ; Title/Abstract Full Text Show Details
Target
enzyme:Wild
Assay Description
Effect : enzyme; inhib. of Bioassay : enzyme from cell-free extracts of the strain Pseudomonas sp. RW31 after growth with 4-sulfophthalate or phthalate
Results
Ki = 7.4 μM (exctract of cells grown with 4-sulfophthalate); Ki = 7.6 μM (extract of cells grown with phthalate); competitive inhibition
Citation
Richter; Wittich
Biodegradation, 1994 , vol. 5, # 1 p. 63 - 69 Title/Abstract Full Text View citing articles Show Details
Effect
Toxic
Assay Description
179 of 515
Target : Salvinia molesta Mitchell, free-floating fern Bioassay : outdoor conditions effect on the number of healthy fronds (HFN) and biomass
Citation
Pandey, D. K.
Journal of Chemical Ecology, 1994 , vol. 20, # 12 p. 3111 - 3122 Title/Abstract Full Text View citing articles Show Details
Biological material
pig
Assay Description
Effect : |transmitter releasing Bioassay : control: vehicle; 15 nmol/l substance P as reference comp. (100 percent); NO: nitric oxide; further investigation with NG-monomethyl-L-arginine (L-NMMA), inhibitor of NO synthase artery (2 cm) mounted in organ bath (10 ml, 25 deg C), then increasing conc. of title comp. added; nitric oxide release monitored amperometrically in real time by NO-selective microsensor
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Results
title comp. elicited nonsign. increase of endothelial NO release: Emax = 32.9 percent and pD2 = 6.86; after pretreatment with L-NMMA effect of title comp. did not change sign.: Emax = 30.2 and pD2 = 6.78 (table)
Citation
Taubert, Dirk; Berkels, Reinhard; Klaus, Wolfgang; Roesen, Renate
Journal of Cardiovascular Pharmacology, 2002 , vol. 40, # 5 p. 701 - 713 Title/Abstract Full Text View citing articles Show Details
Effect
Inflammatory
Assay Description
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Target : murine RAW 264.7 macrophages Bioassay : iNOS: inducible nitric-oxide synthase; COX: cyclooxygenase iNOS and COX-2 expression studied by Western blotting after 6 h of title comp. treatment
Citation
Rapizzi, Elena; Fossati, Silvia; Moroni, Flavio; Chiarugi, Alberto
Molecular Pharmacology, 2004 , vol. 66, # 4 p. 890 - 898 Title/Abstract Full Text View citing articles Show Details
Effect
Phytotoxic
Assay Description
Effect : ion uptake Target : Cucumis sativus L. Tokiwa, cucumber Bioassay : index (R) for ion uptake inhibition: R = 100(k0 - k)/k0, where k is the rate of ion uptake per unit of fresh weight of root, calculated from changes in the amount of the ions in the solution before and after incubation; k0 is k for the control 15- to 17-day-old seedlings; nutrient solution; pH 5.5; growth chamber; 7500 Lx; 25 deg C
Results
inhibition index (R) for NO3(-): 8, H2PO4(-): -21, SO4(2-): 61, K(+): 30, Ca(2+): 38, Mg(2+): -3
Citation
Yu, Jing Quan; Matsui, Yoshihisa
Journal of Chemical Ecology, 1997 , vol. 23, # 3 p. 817 - 827 Title/Abstract Full Text View citing articles Show Details
Biological material
human HEK293 cell line
Assay Description
Effect : gene expression; effect on Bioassay : PPAR-α: peroxisome proliferator-activated receptor-α cells transfected with PPAR-α reporter gene and tK-PPREx3-Luc plasmid; incubation in DMEM/F-12 with title comp.; after 24 h cells were lysed, and PPAR-α acrivity was determined; luciferase assay
Citation
Huang, Tom Hsun-Wei; Peng, Gang; Kota, Bhavani Prasad; Li, George Qian; Yamahara, Johji; Roufogalis, Basil D.; Li, Yuhao
British Journal of Pharmacology, 2005 , vol. 145, # 6 p. 767 - 774 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : LPS: lipopolysaccharide; iNOS: inducible nitric oxide synthase macrophages treated with 5 μg/ml LPS and title comp. for 18 h; total protein extracted, iNOS protein determiend by Western blotting; α-tubulin and nitrite also assayed
Results
title comp. reduced iNOS protein by 92 percent
Citation
Lin, Yu-Li; Lin, Jen-Kun
Molecular Pharmacology, 1997 , vol. 52, # 3 p. 465 - 472 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : inhibition of C24Δ6 desaturation
Results
desaturation index = 0.13
Citation
Nakano; Shirasaka; Koyama; Hino; Murakami; Shimizu; Yoshizumi
Bioscience, biotechnology, and biochemistry, 2000 , vol. 64, # 8 p. 1641 - 1650
Title/Abstract Full Text View citing articles Show Details
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Biological material
Rattus norvegicus
Assay Description
Effect : inhibition of Δ5 desaturation
Results
desaturation index = 0.46
Citation
Nakano; Shirasaka; Koyama; Hino; Murakami; Shimizu; Yoshizumi
Bioscience, biotechnology, and biochemistry, 2000 , vol. 64, # 8 p. 1641 - 1650 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : inhibition of Δ6 desaturation
Results
desaturation index = 3.40
Citation
Nakano; Shirasaka; Koyama; Hino; Murakami; Shimizu; Yoshizumi
Bioscience, biotechnology, and biochemistry, 2000 , vol. 64, # 8 p. 1641 - 1650 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
188 of 515
Results
SAA (μmol-1*l): 750 and 100 (for Cu(2+) oxidation) and 90 and 30 (for 2,2'-azobis(2-aminopropane) hydrochloride oxidation) at concentration 0.2 and 1 μmol LDL, respectively
Citation
Cartron, Emeline; Carbonneau, Marie-Annette; Fouret, Gilles; Descomps, Bernard; Leger, Claude L.
Journal of Natural Products, 2001 , vol. 64, # 4 p. 480 - 486 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Target : human low-density lipoprotein Bioassay : low-density lipoprotein (LDL) (0.2 or 1 μmol/l) in PBS buffer; title compound inhibited with Cu(2+) (5 μmol/l) or AAPH (2.5 μmol/l) at 37 deg C for 1 h; production of conjugated dienes assessed; specific antioxidant activity (SAA) measured
Target : erythrocytes of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride erythrocyte suspension at 5% hematocrit preincubated with title comp. for 30 min at 37 deg C followed by incubation with AAPH (25 mmol/l) in phosphate buffered saline (pH 7.4) for up to 6 h at 37 deg C; hemolysis of erythrocytes determined
Results
title comp. decreased AAPH-induced hemolysis; fig.
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Target : erythrocytes of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride erythrocyte suspension at 5% hematocrit preincubated with title comp. for 30 min at 37 deg C followed by incubation with AAPH (25 mmol/l) in phosphate buffered saline (pH 7.4) for 6 h at 37 deg C and superoxide dismutase (SOD) in cells measured
Results
title comp. decreased AAPH-induced decrease in SOD content; table
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
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Effect Assay Description
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title comp. in dose-depend. manner decreased AAPH-induced MDA formation; table
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
title comp. at conc. of 10-50 μg/ml decreased CuSO4-induced oxidation of lipoprotein; fig.
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target : low density lipoprotein of human Bioassay : lipoprotein (200 μg protein/ml) oxidized by sodium nitroprusside (75 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein assayed using electrophoretic mobility analysis
Results
title comp. decreased sodium nitroprusside-induced oxidation of lipoprotein; fig.
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Target : low density lipoprotein of human Bioassay : lipoprotein (200 μg protein/ml) oxidized by CuSO4 (20 μmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein assayed using electrophoretic mobility analysis
Results
Assay Description
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Target : erythrocytes of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride; MDA: malondialdehyde erythrocyte suspension at 5% hematocrit preincubated with title comp. for 30 min at 37 deg C followed by incubation with AAPH (25 mmol/l) in phosphate buffered saline (pH 7.4) for 6 h at 37 deg C; lipid peroxidation assayed by MDA measurement
Results
Assay Description
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Antioxidant
Target : low density lipoprotein of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride lipoprotein (200 μg protein/ml) oxidized by AAPH (3 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein assayed using electrophoretic mobility analysis
Results
title comp. at conc. of 30 and 50 μg/ml decreased AAPH-induced oxidation of lipoprotein; fig.
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Target : low density lipoprotein of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride; reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml) lipoprotein (200 μg protein/ml) oxidized by AAPH (3 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using determination of total cholesterol and assessment of cholesterol degradation
Results
title comp. decreased AAPH-induced cholesterol degradation; effect of title comp. was similar to that of trolox; table
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114
Title/Abstract Full Text View citing articles Show Details
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Effect Assay Description
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title comp. decreased AAPH-induced oxidation of lipoprotein; effect of title comp. was similar to that of trolox; table
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
title comp. decreased CuSO4-induced cholesterol degradation; effect of title comp. was stronger than that of reference comp.; table
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target : low density lipoprotein of human Bioassay : reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml); TBARS: thiobarbituric acid reactive substances lipoprotein (200 μg protein/ml) oxidized by CuSO4 (20 μmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using TBARS formation assay
Results
title comp. decreased CuSO4-induced oxidation of lipoprotein; effect of title comp. was stronger than that of reference comp.; table
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Target : low density lipoprotein of human Bioassay : reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml) lipoprotein (200 μg protein/ml) oxidized by CuSO4 (20 μmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using determination of total cholesterol and assessment of cholesterol degradation
Results
Assay Description
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Target : low density lipoprotein of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride; reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml); TBARS: thiobarbituric acid reactive substances lipoprotein (200 μg protein/ml) oxidized by AAPH (3 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using TBARS formation assay
Results
Assay Description
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Antioxidant
Target : low density lipoprotein of human Bioassay : reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml); TBARS: thiobarbituric acid reactive substances lipoprotein (200 μg protein/ml) oxidized by sodium nitroprusside (75 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using TBARS formation assay
Results
title comp. decreased sodium nitroprusside-induced oxidation of lipoprotein; effect of title comp. was similar to that of trolox; table
Citation
Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling
Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
Results
Target : rat hepatoma dRLh-84 cells Bioassay : further study with Ca(2+) chelator BAPTA-AM, calmodulin inhibitor W-7, EGTA, Ca(2+) channel blocker verapamil, calpeptin, NADPH oxidase inhibitor DPhI cells incubated with title comp. for 6 h; cell viability determined by MTT assay title comp. completely killed cells after 6 h incubation; BAPTA-AM abrogated title comp.-induced cell death; W-7, EGTA inhibited cell death; verapamil, calpeptin and DPhI failed to show inhibitory activity
against title comp.-induced cell death; fig.
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Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human PLC/PRF/5 cell line
Assay Description
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Results
title comp. completely killed the cells after 6 h incubation; BAPTA-AM abrogated title comp.-induced cell death; W-7, EGTA hd no effect; verapamil, calpeptin and DPhI failed to show inhibitory activity against title comp.-induced cell death; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human HtTA-1 cell line
Assay Description
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Bioassay : further study with Ca(2+) chelator BAPTA-AM, calmodulin inhibitor W-7, EGTA, Ca(2+) channel blocker verapamil, calpeptin, NADPH oxidase inhibitor DPhI cells incubated with title comp. for 6 h; cell viability determined by MTT assay
Bioassay : further study with Ca(2+) chelator BAPTA-AM, calmodulin inhibitor W-7, EGTA, Ca(2+) channel blocker verapamil, calpeptin, NADPH oxidase inhibitor DPhI cells incubated with title comp. for 6 h; cell viability determined by MTT assay
Results
title comp. completely killed the cells after 6 h incubation; BAPTA-AM abrogated title comp.-induced cell death; W-7, EGTA hd no effect; verapamil, calpeptin and DPhI failed to show inhibitory activity against title comp.-induced cell death; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : cell cycle distribution; effect on Target : human promyelocytic leukemia HL-60RG cells Bioassay : cells cultured in RPMI-1640 medium; incubated with title comp. for 2 or 6 h; DNA content in each cell cycle phase analysed by flow cytometry method (FACScan)
Results
flow cytometric analyses revealed that smaller DNA, which resulted from DNA degradation was detected in cells at 2 h after treatment with title comp. and cell cycle distribution was not changed during the incubation period; figure
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : cell cycle distribution; effect on Target : rat hepatoma dRLh-84 cells Bioassay : cells cultured in RPMI-1640 medium; incubated with title comp. for 2 or 6 h; DNA content in each cell cycle phase analysed by flow cytometry method (FACScan)
Results
appearance of DNA with low fluorescent intensity was not observed after title comp. treatment; cell cycle distributions were not changed during the incubation period; figure
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
Target : rat hepatoma dRLh-84 cells Bioassay : further study with N-acetyl-L-cysteine (NAC), catalase and ascorbic acid cells incubated with title comp. for 6 h; cell viability determined by MTT assay
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Results
title comp. completely killed the cells after 6 h incubation; NAC and catalase protected against title comp.-induced cell death; ascorbic acid abolished the death of cells; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Results
title comp. completely killed the cells after 6 h incubation; H-7, H-89 and genistein failed to protect against title comp.-induced cell death or showed only a weak stimulatory or inhibitory effect that was not significant; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human PLC/PRF/5 cell line
Assay Description
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Bioassay : further study with N-acetyl-L-cysteine (NAC), catalase and ascorbic acid cells incubated with title comp. for 6 h; cell viability determined by MTT assay
Results
title comp. completely killed the cells after 6 h incubation; NAC and catalase protected against title comp.-induced cell death; ascorbic acid abolished the death of PLC/PRF/5 cells; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human PLC/PRF/5 cell line
Assay Description
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Target : rat hepatoma dRLh-84 cells Bioassay : further study with protein kinase C inhibitor H-7, protein kinase A inhibitor H-89 and tyrosine kinase inhibitor genistein cells incubated with title comp. for 6 h; cell viability determined by MTT assay
Bioassay : further study with protein kinase C inhibitor H-7, protein kinase A inhibitor H-89 and tyrosine kinase inhibitor genistein cells incubated with title comp. for 6 h; cell viability determined by MTT assay
Results
title comp. completely killed the cells after 6 h incubation; H-7, H-89 and genistein failed to protect against title comp.-induced cell death or showed only a weak stimulatory or inhibitory effect that was not significant; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human HtTA-1 cell line
Assay Description
Bioassay : further study with N-acetyl-L-cysteine (NAC), catalase and ascorbic acid cells incubated with title comp. for 6 h; cell viability determined by MTT assay
Results
title comp. completely killed the cells after 6 h incubation; NAC and catalase protected against title comp.-induced cell death; ascorbic acid slightly stimulated death of cells; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
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Effect
Cytotoxic
Biological material
human HtTA-1 cell line
Assay Description
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Results
title comp. completely killed the cells after 6 h incubation; H-7, H-89 and genistein failed to protect against title comp.-induced cell death or showed only a weak stimulatory or inhibitory effect that was not significant; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Biological material
human PLC/PRF/5 cell line
Assay Description
Effect : cell cycle distribution; effect on Bioassay : cells cultured in RPMI-1640 medium; incubated with title comp. for 2 or 6 h; DNA content in each cell cycle phase analysed by flow cytometry method (FACScan)
Results
appearance of DNA with low fluorescent intensity was not observed after title comp. treatment; cell cycle distributions were not changed during the incubation period; figure
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Biological material
human HtTA-1 cell line
Assay Description
Effect : cell cycle distribution; effect on Bioassay : cells cultured in RPMI-1640 medium; incubated with title comp. for 2 or 6 h; DNA content in each cell cycle phase analysed by flow cytometry method (FACScan)
Results
appearance of DNA with low fluorescent intensity was not observed after title comp. treatment; cell cycle distributions were not changed during the incubation period; figure
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Bioassay : further study with protein kinase C inhibitor H-7, protein kinase A inhibitor H-89 and tyrosine kinase inhibitor genistein cells incubated with title comp. for 6 h; cell viability determined by MTT assay
Target : xanthine oxidase Bioassay : negative control: 100% DMSO; positive control: 600 U/ml SOD; SC50: concentration of title comp. that scavenge 50% of superoxide radicals; XO: xanthine oxidase title comp. added to mixture contg. NaHCO3 buffer (50 mmol/l), hypoxanthine (0.5 mmol/l), EDTA (1 mmol/l), and XTT (0.25 mmol/l); reaction initiated by addition of XO (200 mU/ml); reduced XTT production determined at 480 nm every 20 s for 5 min
Results
SC50 0.7 mg/l
Citation
Rangkadilok, Nuchanart; Sitthimonchai, Somkid; Worasuttayangkurn, Luksamee; Mahidol, Chulabhorn; Ruchirawat, Mathuros; Satayavivad, Jutamaad
Food and Chemical Toxicology, 2007 , vol. 45, # 2 p. 328 - 336 Title/Abstract Full Text View citing articles Show Details
Target
xanthine oxidase:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : negative control: 100% DMSO; positive control: allopurinol title comp. added to reaction mixture contg. NaHCO3 (50 mmol/l) buffer, xanthine (1 mmol/l), and EDTA (1 mmol/l); reaction initiated by addition of enzyme (200 mU/ml); rate of uric acid production immediately measured at 295 nm every 20 s for 5 min
Results
title comp. inhibited xanthine oxidase by 21%
Citation
Rangkadilok, Nuchanart; Sitthimonchai, Somkid; Worasuttayangkurn, Luksamee; Mahidol, Chulabhorn; Ruchirawat, Mathuros; Satayavivad, Jutamaad
Food and Chemical Toxicology, 2007 , vol. 45, # 2 p. 328 - 336 Title/Abstract Full Text View citing articles Show Details
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Effect
Pesticidal
Biological material
Meloidogyne incognita
Assay Description
Effect : nematicidal Bioassay : larva
Results
maximal mortality at 0.5% 92 %
Citation
Sultana, Nighat; Akhter, Musarrat; Khatoon, Zakia
Natural Product Research, 2010 , vol. 24, # 5 p. 407 - 415 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : free radical scavenging Bioassay : 2,2-diphenyl-1-picrylhydrazyl colorimetric method
Results
SC50 scavenging concentration 5.17 μmol
Citation
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
Biological material
murine cells
Assay Description
Effect : α-MSH-induced melanin production spectrophotometric assay
Results
melanin content 68.8 percent
Citation
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Species : not explicitly stated by authors ferric reducing antioxidant power (FRAP) assay; AEAC: ascorbic acid equivalent antioxidant capacity
Results
AEAC 21.267 mg/ml
Citation
Gourine, Nadhir; Yousfi, Mohamed; Bombarda, Isabelle; Nadjemi, Boubakeur; Gaydou, Emile
JAOCS, Journal of the American Oil Chemists' Society, 2010 , vol. 87, # 2 p. 157 - 166 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : LOX-1 hydroperoxidative activity Bioassay : RNO and linoleic acid RNO: 4-nitroso-N,N-dimethylaniline; LOX-1: lipoxygenase-1 isoenzyme
Results
percent increase in lag phase 22 %
Citation
Pastore, Donato; Laus, Maura N.; Tozzi, Damiana; Fogliano, Vincenzo; Soccio, Mario; Flagella, Zina
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 20 p. 9682 - 9692 Title/Abstract Full Text View citing articles Show Details
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Effect
Antioxidant
Assay Description
Effect : free radical scavenging Target : 2,2-diphenyl-1-picrylhydrazyl radical Bioassay : 2,2-diphenyl-1-picrylhydrazyl radical time of test: 30 min
Results
scavenging rate 23 - 99.2 percent
Citation
Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details
Effect
Antihemolytic
Biological material
human erythrocyte
Assay Description
Effect : AAPH-induced hemolysis AAPH: 2,2'-azobis(2-amidinopropane) hydrochloride; effect determined after 3 h; control: 17%
Results
hemolysis rate 3 percent
Citation
Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details
Effect
Antihemolytic
Biological material
human erythrocyte
Assay Description
Effect : AAPH-induced hemolysis AAPH: 2,2'-azobis(2-amidinopropane) hydrochloride; effect determined after 6 h; hemolysis rate at conc. of 200 μmol/l: 72%; control: 78%
Citation
Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details
Effect
Antihemolytic
Biological material
human erythrocyte
Assay Description
Effect : cumene hydroperoxide-induced hemolysis time of test: 2 h; control: 72.9%; hemolysis rate at 10 μmol/l: 67%
Results
hemolysis rate 17 percent
Citation
Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details
Effect
Hemolytic
Biological material
human erythrocyte
Assay Description
Effect : hemolysis hemolysis rate: 4.7%; effect determined after 6 h; control hemolysis rate: 3.7%
Citation
Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details
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Biological material
human erythrocyte
Assay Description
Effect : AAPH-induced intracellular GSH depletion AAPH: 2,2'-azobis(2-amidinopropane) hydrochloride; time of test: 2 h; GSH intracellular level: 4.5 μmol/lg Hb; GSH: glutathione; DTNB method; positive control: 4.2 μmol/lg Hb
Citation
Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details
Effect
Antidiabetic
Biological material
Rattus norvegicus
Assay Description
Effect : sugar level Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg)
Citation
Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
Rattus norvegicus
Assay Description
Effect : malondialdehyde level Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg)
Citation
Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : incidence of cataract eye injury Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg); hematoxylin-eosin staining, light microscopy
Citation
Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : insulin level hormone release Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg)
Citation
Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : islets injury pancreas injury Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg); hematoxylin-eosin staining, light microscopy
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Citation
Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : microaneurysm in lenses eye injury Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg); hematoxylin-eosin staining, light microscopy
Citation
Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : tumor formation Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg); hematoxylin-eosin staining, light microscopy
Citation
Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : calcium uptake; effect on Target : rat pituitary GH4C1 cells Bioassay : BSS: buffered salt solution; vehicle control; reference comp.: verapamil (IC50 = 3.0 μg/ml) cells incubated with BSS containing title comp., 50 mmol/l K(1+) and 45Ca(2+) at 37 deg C, for 15 min; washed; calcium uptake via voltage-operated calcium channels measured as radioactivity by liquid scintillation counting
Citation
Summanen, Jari; Vuorela, Pia; Rauha, Jussi-Pekka; Tammela, Paeivi; Marjamaeki, Krista; Pasternack, Michael; Toernquist, Kid; Vuorela, Heikki
European Journal of Pharmacology, 2001 , vol. 414, # 2-3 p. 125 - 133 Title/Abstract Full Text View citing articles Show Details
Target
Estrogen receptor beta:Wild
Assay Description
Effect : |receptor; binding activity Bioassay : competition binding assay with radiolabeled estradiol as radioligand
Citation
Mallavadhani, Uppuluri Venkata; Narasimhan, Kilambi; Sudhakar, Akella Venkata Subrahmanya; Mahapatra, Anita; Li, Wenkui; Van Breemen, Richard Bruce
Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 5 p. 740 - 744 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |receptor; binding activity Target : estrogen receptor-α Bioassay : competition binding assay with radiolabeled estradiol as radioligand
Citation
Mallavadhani, Uppuluri Venkata; Narasimhan, Kilambi; Sudhakar, Akella Venkata Subrahmanya; Mahapatra, Anita; Li, Wenkui; Van Breemen, Richard Bruce
Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 5 p. 740 - 744 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : calcium deposition; increase of Target : pre-osteoblastic cell line MC3T3-E1 of mouse Bioassay : Following Experiment 1 which investigates differentiating pre-osteoblastic cells into osteoblastic cells, some of organic compounds were investigated whether they actually enhance calcium deposition or not. Indomethacin (commercialized by Funakoshi, Co., Ltd., Tokyo, Japan) (positive control), kaempferol
Citation
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Patent: EP1514540 A1, 2005 ; Title/Abstract Full Text Show Details
Target
alkaline phosphatase:Wild
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Assay Description
Effect : alkaline phosphatase; induction of Bioassay : Culturing mouse pre-osteoblastic cells Mouse pre-osteoblastic cell line MC3T3-E1 was suspended in α-MEM medium (pH6.8) supplemented with 10mM HEPES and 10(v/v)% calf serum albumin (produced by Gibco BRL Company), which contains the ingredients listed in Table 7 to be concentration of 5&times;104
Citation
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Patent: EP1514540 A1, 2005 ; Title/Abstract Full Text Show Details
Assay Description
Effect : Herpes simplex virus (HSV) infection; effect on Target : with Herpes simplex virus (HSV) infection of human Bioassay : Example 7 External Treatment of HSV Infection in Clinical Tests Twenty-two patients who were clinically diagnosed with HSV infection were randomly selected and divided into two groups. Acyclovir ointment and micro emulsion containing propyl gallate prepared as described in Example 1 were applied to
Results
treatment with a microemulsion containing the title compound was more effective than treatment with acyclovir; treatment with title compound-containing microemulsion gave an average time for recovery of 3 days compared with average recovery time of
Citation
Weihua, QIN
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antiviral
Assay Description
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Results
no Human papillomavirus HPV 6/11 virus remained 24 hours after treatment with 50 &micro;l micro emulsion containing 10 % of title compound
Citation
Weihua, QIN
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antiviral
Assay Description
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Target : Human papillomavirus 6/11 Bioassay : Example 4 Drug Screening Through Quantitative Fluorescent PCR Analysis Samples The test compounds listed in Table 1 below were prepared as micro emulsions as described in Example 1. Saline water was used as the control. Methyl 2,3,4-trihydroxybenzoate was prepared as follows: 10 g of 2,3,4-trihydroxybenzoic
Target : Human papillomavirus 6/18 Bioassay : Example 4 Drug Screening Through Quantitative Fluorescent PCR Analysis Samples The test compounds listed in Table 1 below were prepared as micro emulsions as described in Example 1. Saline water was used as the control. Methyl 2,3,4-trihydroxybenzoate was prepared as follows: 10 g of 2,3,4-trihydroxybenzoic
Results
no Human papillomavirus HPV 6/18 virus remained 24 hours after treatment with 50 &micro;l micro emulsion containing 10 % off title compound
Citation
Weihua, QIN
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
Hep-G2/2.2.15 cell line
Assay Description
Effect : HBeAg secretion; inhibition of Bioassay : Example 6 Inhibition Effect of Hydroxybenzoic Acid Ester Analogue on Secretion of HBsAg and HBeAg by Hepatitis B 2.2.15 Cell Line Experiment Materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological
Results
treatment with 2 &micro;mol/ml title compound gave an inhibition rate of 9.4%
Citation
Weihua, QIN
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
Hep-G2/2.2.15 cell line
Assay Description
Effect : HBsAg secretion; inhibition of Bioassay : Example 6 Inhibition Effect of Hydroxybenzoic Acid Ester Analogue on Secretion of HBsAg and HBeAg by Hepatitis B 2.2.15 Cell Line Experiment Materials Hepatitis B 2.2.15 cell line was
transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological
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Results
treatment with 2 &micro;mol/ml title compound gave an inhibition rate of 8.3%
Citation
Weihua, QIN
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
human
Assay Description
Effect : condyloma acuminata; effect on Bioassay : Example 5 Clinical Use of Hydroxybenzoic Acid Ester in Treating Condyloma Acuminata Diagnosis Standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of Health
Results
treatment with title compound had more apparent treatment effect compared with recombinant human interferon α-2β gel; treatment with title compound showed that in 4 patients more than 70% of skin lesions disappeared after 1-8 days, 4 patients
Citation
Weihua, QIN
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : HBeAg secretion; inhibition of Target : liver 2.2.15 cells transfected by hepatitis B virus (HBV) DNA Bioassay : Example 6. Inhibition effect of hydroxybenzoic acid ester analogue on secretion of HBsAg by hepatitis B 2.2.15 cell line Experiment materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological Sciences
Results
treatment with the title compound at 2μmol/ml inhibited the rate of HBeAg secretion measured as 9.40% inhibition rate (control=0%)
Citation
QIN, Weihua, F/22 NorthTower
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : HBsAg secretion; inhibition of Target : liver 2.2.15 cells transfected by hepatitis B virus (HBV) DNA Bioassay : Example 6. Inhibition effect of hydroxybenzoic acid ester analogue on secretion of HBsAg by hepatitis B 2.2.15 cell line Experiment materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological Sciences
Results
treatment with the title compound at 2μmol/ml inhibited the rate of HBsAg secretion measured as 8.83% inhibition rate (control=0%)
Citation
QIN, Weihua, F/22 NorthTower
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antiviral
Assay Description
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Target : Human papillomavirus (HPV) 16/18 Bioassay : Example 4. Drug screening through quantitative fluorescent PCR analysis Samples The micro emulsions obtained in Example 1 were used as test samples, and saline water was used as the control. HPV samples: condyloma acuminata samples were taken from clinical patients. The samples were washed with saline
Results
treatment with the title compound at 50μl micro emulsion effectively and rapidly eliminated the number of human papillomavirus (HPV) 16/18 from 1.40E5 (control) to 0copies/ml
Citation
QIN, Weihua, F/22 NorthTower
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antiviral
Assay Description
Target : Human papillomavirus (HPV) 6/11 Bioassay : Example 4. Drug screening through quantitative fluorescent PCR analysis Samples The micro emulsions obtained in Example 1 were used as test samples, and saline water was used as the control. HPV samples: condyloma acuminata samples were taken from clinical patients. The samples were washed with saline
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Results
treatment with the title compound at 50μl micro emulsion effectively and rapidly eliminated the number of human papillomavirus (HPV) 6/11 from 1.45E6 (control) to 0copies/ml
Citation
QIN, Weihua, F/22 NorthTower
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
human
Assay Description
Effect : adverse effect Bioassay : Example 5. Clinical use of hydroxybenzoic acid ester in treating condyloma acuminata Diagnosis standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of
Results
treatment with the title compound did not cause any obvious skin irritation however some patients ocassionally experienced a burning sense
Citation
QIN, Weihua, F/22 NorthTower
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
human
Assay Description
Effect : condyloma acuminata; effect on Bioassay : Example 5. Clinical use of hydroxybenzoic acid ester in treating condyloma acuminata Diagnosis standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of
Results
treatment with the title compound showed that in 50 qualified patients, 2 had recovered within 1-4 days, obvious effects were seen in 3 (1-4 days) and 1 (5-8 days) patient, 4 patients had improved effect
Citation
QIN, Weihua, F/22 NorthTower
Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
human HASMC cell line
Assay Description
Effect : cholesterol efflux; stimulatory effect on Figure 10 is a graph showing the effect of active compounds from EO on efflux of cholesterol in human aortic smooth muscle cells. Confluent culture of H- ASMC in 96 well plates was incubated with [3H] cholesterol (5 μCi/ml) for 24 h. Medium was replaced with fresh medium and incubation with herbal
Results
title compound significantly induced efflux of cholesterol from cells; figure is given
Citation
THE JOHNS HOPKINS UNIVERSITY; MERLION PHARMACEUTICAL PTC LTD
Patent: WO2008/80162 A2, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : |microorganisms Target : Porcellio scaber, isopods Bioassay : adult 20-30 mg, 15 deg C, pH 5.5, feces collected, lyophilized
Results
relative consumption rates 0.02-0.04, approximate digestibility 65-86; test comp. increased number of bacteria, total microbiota counts increased in anterior hundgut
Citation
Zimmer, Martin
Journal of Chemical Ecology, 1999 , vol. 25, # 3 p. 611 - 628 Title/Abstract Full Text View citing articles Show Details
Results
protective activity against cell damage induced by active oxygens, survival 62.4percent at 100 μM, 98.6percent at 500 μM, 84.6percent at 1000 μM (singlet oxygens)
Citation
Masaki, Hitoshi; Atsumi, Takamasa; Sakurai, Hiromu
Phytochemistry (Elsevier), 1994 , vol. 37, # 2 p. 337 - 344 Title/Abstract Full Text View citing articles Show Details
Results
effect on the level of extracellular laccase activity of Botrytis cinerea
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Citation
Marbach, Irith; Harel, Eitan; Mayer, Alfred M.
Phytochemistry (Elsevier), 1983 , vol. 22, # 7 p. 1535 - 1538 Title/Abstract Full Text View citing articles Show Details
Results
in vitro DNA breaking activity
Citation
Yamada; Shirahata; Murakami; et al.
Agricultural and Biological Chemistry, 1985 , vol. 49, # 5 p. 1423 - 1428 Title/Abstract Full Text View citing articles Show Details
Effect
Antithrombotic
Biological material
rabbit thrombocyte
Assay Description
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Results
percent of platelet aggregation: 32.3
Citation
Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Effect
Antithrombotic
Biological material
rabbit thrombocyte
Assay Description
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Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of arachidonic acid (100 μM)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method
Results
percent of platelet aggregation: 58.9
Citation
Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Effect
Antithrombotic
Biological material
rabbit thrombocyte
Assay Description
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Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of arachidonic acid (100 μM)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method
Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of collagen (10 μg/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method
Results
percent of platelet aggregation: 0.0
Citation
Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Effect
Antithrombotic
Biological material
rabbit thrombocyte
Assay Description
Results
Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of collagen (10 μg/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method percent of platelet aggregation: 3.8
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Citation
Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Effect
Antithrombotic
Biological material
rabbit thrombocyte
Assay Description
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Results
percent of platelet aggregation: 14.1
Citation
Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Effect
Antithrombotic
Biological material
rabbit thrombocyte
Assay Description
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Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of PAF (2 ng/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method
Results
percent of platelet aggregation: 18.9
Citation
Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Effect
Antithrombotic
Biological material
rabbit thrombocyte
Assay Description
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Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of PAF (2 ng/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method
Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of thrombin (0.1 U/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method
Results
percent of platelet aggregation: 17.3
Citation
Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
Effect
Antithrombotic
Biological material
rabbit thrombocyte
Assay Description
Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of thrombin (0.1 U/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method
Results
percent of platelet aggregation: 54.4
Citation
Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details
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Assay Description
Effect : |DNA; examination of Target : calf thymus DNA Bioassay : sodium salt of DNA, average molecular weight 1E6; Tris-HCl pH 7.5; room temp; various incubation time (up to 5 h); effect on breakage of calf thymus DNA; DNA hydrolyse; kinetic
Results
ca. 45 percent DNA was degraded after 5 h at 0.4 mM; dose- and time-respone relationships
Citation
Khan, Nelofer S.; Hadi
Mutagenesis, 1998 , vol. 13, # 3 p. 271 - 274 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |DNA; examination of Target : supercoiled plasmid pBr322 DNA Bioassay : Tris-HCl pH 7.5; room temp; incubation time: 1 h; agarose gel electrophoresis assay; DNA cleavage assay
Results
title comp. was capable of DNA cleavage resulting in linear molecules with smaller sized fragments
Citation
Khan, Nelofer S.; Hadi
Mutagenesis, 1998 , vol. 13, # 3 p. 271 - 274 Title/Abstract Full Text View citing articles Show Details
Results
in vitro trypanocidal activity against Trypanosoma brucei brucei (GUTat 3.1): on bloodstream forms: GI50=15.60 μM, TGI=31.28 μM, LD50=46.96 μM, and on procyclic forms: GI50=14.44 μM, TGI=20.78 μM, LD50=30.02 μM
Citation
Koide, Tatsuo; Nose, Mitsuhiko; Inoue, Makoto; Ogihara, Yukio; Yabu, Yoshisada; Ohta, Nobuo
Planta Medica, 1998 , vol. 64, # 1 p. 27 - 30 Title/Abstract Full Text View citing articles Show Details
Results
inhibition of lipid oxidation in lecithin liposome in the absence (PC) or presence of bovine serum albumin (PC-BSA) at 5 μM: conjugated diene production = -34.6percent (PC) and -23.8percent (PC-BSA), hexanal production = -53.8percent (PC) and -248.5per
Citation
Heinonen, Marina; Rein, Dietrich; Satue-Gracia, M. Teresa; Huang, Shu-Wen; German, J. Bruce; Frankel, Edwin N.
Journal of Agricultural and Food Chemistry, 1998 , vol. 46, # 3 p. 917 - 922 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : in vitro; effect on 6β- and 16α-androstenedione hydroxylases assessed; 43.75 μmol/l androstenedione; assay buffer; 37 deg C; incubated for 10 min; liquid scintillation counting
Results
title comp. changed 6β-/16α-androstenedione hydroxylase activity from 0.66/1.06 to 0.43/0.60 nmol/mg/min
Citation
Stupans, Ieva; Kirlich, Amra; Tuck, Kellie L; Hayball, Peter J
Journal of agricultural and food chemistry, 2002 , vol. 50, # 8 p. 2464 - 2469 Title/Abstract Full Text Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : in vitro; effect on 6β-androstenedione hydroxylase assessed; 43.75 μmol/l androstenedione; assay buffer; 37 deg C; incubated for 10 min; liquid scintillation counting
Results
title comp. changed enzyme activity from 0.50 to 0.25 nmol/mg/min
Citation
Stupans, Ieva; Kirlich, Amra; Tuck, Kellie L; Hayball, Peter J
Journal of agricultural and food chemistry, 2002 , vol. 50, # 8 p. 2464 - 2469 Title/Abstract Full Text Show Details
Effect
Antioxidant
Assay Description
Target : Hooded Wistar rat liver microsomes
Bioassay : in vitro; effect on reactive oxygen species generation assessed; DCF-DA preincubated microsomes assay buffer, pH 7.4; 37 deg C; incubated for 25 min; reactive oxygen species generation monitored spectrofluorometrically
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Results
title comp. changed reactive oxygen species generation from 21 to 14.4 nmol of DCF/mg/h
Citation
Stupans, Ieva; Kirlich, Amra; Tuck, Kellie L; Hayball, Peter J
Journal of agricultural and food chemistry, 2002 , vol. 50, # 8 p. 2464 - 2469 Title/Abstract Full Text Show Details
Effect
Antioxidant
Assay Description
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Results
title comp. changed reactive oxygen species generation from 14.4 to 10.2 nmol of DCF/mg/h
Citation
Stupans, Ieva; Kirlich, Amra; Tuck, Kellie L; Hayball, Peter J
Journal of agricultural and food chemistry, 2002 , vol. 50, # 8 p. 2464 - 2469 Title/Abstract Full Text Show Details
Target
Tumor necrosis factor:Wild
Assay Description
Effect : TNF-α production; induction of Bioassay : incubation continued for 24 h; TNF-α level determined by ELISA in vitro; effect of title comp. on TNF-α production in LPS/INF-γ - activated cells; 6E5 cells well incubated with title comp. in DMEM with 10 percent FBS at 37 deg C for 1 h before stimulation with 10 ng/ml LPS and 10-50 U/ml IFN-γ
Results
TNF-α ( percent relative to LPS/IFN-γ alone) / dose (μmol/l): 122.0/16, 112.1/31, 117.4/63, 123.8/125, 130.6/250, 48.0/500
Citation
Wang, Jian; Mazza
Journal of agricultural and food chemistry, 2002 , vol. 50, # 15 p. 4183 - 4189 Title/Abstract Full Text Show Details
Biological material
CHO-K1 cell line
Assay Description
Effect : |sister chromatid exchange; examination of Bioassay : SOD: superoxide dismutase; CAT: catalase; SCE: sister-chromatid exchance 6E5 cells were seeded into plugged tissue-culture flasks; after 48 h title comp. with or without oxygen radical scavengers (SOD and CAT) was added; cells were treated for 3 h; then incubated for an additional 27 h in plugged flasks
Results
induction of SCEs at conc. >= 0.5 mM; SOD+CAT inhibited SCE induction at 1.5- 2 mM of title comp.; increase of SCE freq. at 1 mM and +SOD; 1 mM of title comp. added with CAT or CAT+SOD to the culture no longer caused a signif. increase in the SCE
Citation
Tayama, Sumiko; Nakagawa, Yoshio
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2001 , vol. 498, # 1-2 p. 117 - 127 Title/Abstract Full Text View citing articles Show Details
Effect
Antiproliferative
Biological material
CHO-K1 cell line
Assay Description
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Target : human liver microsomes Bioassay : in vitro; effect on reactive oxygen species generation assessed; DCF-DA preincubated microsomes assay buffer, pH 7.4; 37 deg C; incubated for 25 min; reactive oxygen species generation monitored spectrofluorometrically
Bioassay : AT: 3-amino-1,2,4-triazole 6E5 cells were seeded into plugged tissue-culture flasks; after 48 h title comp. with inhibitor of catalase activity (AT) was added; cells were treated for 3 h; then incubated for an additional 27 h in plugged flasks
Results
no proliferating cells were observed
Citation
Tayama, Sumiko; Nakagawa, Yoshio
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2001 , vol. 498, # 1-2 p. 117 - 127 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Biological material Assay Description
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at conc. >= 0.5 mM no inducing of CAs; SOD+CAT improved cell-cycle delay (from 78 or 72 percent to 92 or 90 percent DSC) at 1.5 and 2 mM of title comp.
Citation
Tayama, Sumiko; Nakagawa, Yoshio
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2001 , vol. 498, # 1-2 p. 117 - 127 Title/Abstract Full Text View citing articles Show Details
Effect
Cytostatic
Biological material
human WIL2 NS cell line
title comp. had no significant influence on nuclear division index of H2O2/tert-butylhydroperoxide treated cells; table
Citation
Sugisawa, Ayako; Kimura, Michiyo; Fenech, Michael; Umegaki, Keizo
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 559, # 1-2 p. 97 - 103 Title/Abstract Full Text View citing articles Show Details
Effect
Cytostatic
Biological material
human WIL2 NS cell line
Bioassay : control: untreated cells; positive controls: H2O2, tert-butylhydroperoxide; cells isolated from spleen of Caucasian male with hereditary spherocytic anemia was used cell suspensions incubated with title comp. for 60 min; resuspended in RPMI 1640 medium; after 42 h of culture, cells harvested; nuclear division index determined by CBMN assay
Citation
Sugisawa, Ayako; Kimura, Michiyo; Fenech, Michael; Umegaki, Keizo
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 559, # 1-2 p. 97 - 103 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Biological material
human WIL2 NS cell line
Assay Description
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Bioassay : control: untreated cells; cells isolated from spleen of Caucasian male with hereditary spherocytic anemia was used cell suspensions incubated with title comp. for 60 min at 37 deg C; exposed to H2O2/tert-butylhydroperoxide at for 30 min; resuspended in RPMI 1640 medium; after 42 h of culture, cells harvested; nuclear division index determined by CBMN assay
Results
Assay Description
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Bioassay : SOD: superoxide dismutase; CAT: catalase; CA: chromosome aberration; ERDs: endoreduplications; DSC: cell-cycle delay 6E5 cells were seeded into plugged tissue-culture flasks; after 48 h title comp. with or without oxygen radical scavengers (SOD and CAT) was added; cells were treated for 3 h; then incubated for an additional 27 h in plugged flasks
Results
Assay Description
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CHO-K1 cell line
Bioassay : control: untreated cells; t-BuOOH: tert-butylhydroperoxide; chromosomal damage: number of micronucleated binucleate cells/1000 binucleated cells; cells isolated from spleen of Caucasian male with hereditary spherocytic anemia was used cell suspensions incub. with title comp. for 60 min at 37 deg C; exposed to H2O2/t-BuOOH for 30 min; resuspended in RPMI 1640 medium; after 42 h of culture, cells harvested; chromosomal damage assessed by CBMN assay
Results
title comp. even at 1 μmol/l prevented the H2O2-induced chromosomal damage; title comp. did not prevent inhibition of t-BuOOH-induced chromosomal damage, even at 10 μmol/l; diagram, table
Citation
Sugisawa, Ayako; Kimura, Michiyo; Fenech, Michael; Umegaki, Keizo
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 559, # 1-2 p. 97 - 103 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Biological material
human WIL2 NS cell line
Assay Description
Bioassay : control: untreated cells; positive controls: H2O2, tert-butylhydroperoxide; chromosomal damage: number of micronucleated binucleate cells/1000 binucleated cells; cells isolated from spleen of Caucasian male with hereditary spherocytic anemia was used cell suspensions incubated with title comp. for 60 min; resuspended in RPMI 1640 medium; after 42 h of culture, cells harvested; chromosomal damage assessed by CBMN assay
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Citation
Sugisawa, Ayako; Kimura, Michiyo; Fenech, Michael; Umegaki, Keizo
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 559, # 1-2 p. 97 - 103 Title/Abstract Full Text View citing articles Show Details
Effect
Antineoplastic
Biological material
human T-47D cell line
Assay Description
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Bioassay : HIF-1: hypoxia-inducible factor-1 in vitro; effect of title comp. on HIF-1 activity monitored using a luciferase reporter under the control of HRE from the erythropoietin gene (pTK-HRE3-luc); DMEM/F12 medium; incubated for 16 h at 37 deg C under normoxic and hypoxic conditions (1% O2)
Citation
Zhou, Yu-Dong; Kim, Yong-Pil; Li, Xing-Cong; Baerson, Scott R.; Agarwal, Ameeta K.; Hodges, Tyler W.; Ferreira, Daneel; Nagle, Dale G.
Journal of Natural Products, 2004 , vol. 67, # 12 p. 2063 - 2069 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : cell membrane; binding affinity Target : Caco-2 cell membranes Bioassay : BSA: bovine serum albumin; DPBS: Dulbecco's phosphate buffered saline; SHP: streptavidin-horseradish peroxidase; IC50 is concentration at which 50 percent inhibition of UEA1 binding occurred cell membranes coated onto microtiter plates overnight, 4 deg C; blocked with BSA in DPBS, room temp.; washed, added BSA-DPBS, biotin-labeled UEA1 and title comp., incubated overnight, 4 deg C; detected bound UEA1 using SHP and o-phenylenediamine by UV
Citation
Hamashin, Christa; Spindler, Lisa; Russell, Shannon; Schink, Amy; Lambkin, Imelda; O'Mahony, Daniel; Houghten, Richard; Pinilla, Clemencia
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 23 p. 4991 - 4997 Title/Abstract Full Text View citing articles Show Details
Biological material
3T3-L1 cell line
Assay Description
Effect : GLUT4 translocation Target : myc-GLUT4-GFP chimera 70 % confluency cell culture tested; incubation time with title comp.: 30 min; GLUT4: glucose transporter 4
Results
maximal percentage increase 90 %
Citation
Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar
FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details
Biological material
3T3-L1 cell line
Assay Description
Effect : phosphorylation Target : ;AMPK differentiated cells tested; incubation time with title comp.: 30 min; AMPK: AMP-activated protein kinase
Citation
Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar
FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details
Biological material
3T3-L1 cell line
Assay Description
Effect : phosphorylation Target : ;Akt differentiated cells tested; incubation time with title comp.: 30 min; AMPK: AMP-activated protein kinase
Citation
Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar
FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details
Biological material
3T3-L1 cell line
Assay Description
Effect : phosphorylation
Target : ;aPKCζ/λ differentiated cells tested; incubation time with title comp.: 30 min; aPKCζ/λ: atypical protein kinase Cζ/λ
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Results
fold increase 1.4
Citation
Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar
FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |enzyme; inhibition of Bioassay : effect on enzyme activity evaluated using spectrophotometric method; linoleic acid used as enzyme substrate; assay buffer, pH 8.0; 25 deg C; formation of product, 13S-linoleic acid hydroperoxide, monitored continuously at 234 nm
Citation
Ha, Tae Joung; Nihei, Ken-Ichi; Kubo, Isao
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 10 p. 3177 - 3181 Title/Abstract Full Text View citing articles Show Details
Effect
Antiadhesive
Assay Description
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Target : type O erythrocytes Bioassay : ICAM 1: intercellular adhesion molecule 1; IE: infected erythrocytes; PS prepd. by culturing Plasmodium falciparum ITO4-A4 in type O erythrocytes in RPMI 1640 medium; control: DMSO microslides coated for 72 h at 37 deg C with human ICAM 1-Fc; blocked overnight (4 deg C); title comp. added to parasite suspension (PS); after 20 min, PS allowed to flow through microslides (5 min); stationary IE counted; IE rolling velocity analyzed
Results
title comp. had no major effect on adhesion; diagram
Citation
Dormeyer, Matthias; Adams, Yvonne; Kramer, Bernd; Chakravorty, Srabasti; Tse, Man Tsuey; Pegoraro, Stefano; Whittaker, Lisa; Lanzer, Michael; Craig, Alister
Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 2 p. 724 - 730 Title/Abstract Full Text View citing articles Show Details
Biological material
Mus musculus 3T3-L1 cell line
Assay Description
Effect : cell number cells harvested 8 days after initiation of differentiation
Citation
Hsu, Chin-Lin; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 21 p. 8404 - 8410 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : free radical scavenging Target : linoleic acid peroxyl radical Bioassay : linoleic acid peroxyl radical test carried out in micelle system prepared using rac-1-lauroylglycerol and deoxycholic acid sodium salt
Results
1/IC50 reciprocal of inhibitory concentration 1.24 l/μmol
Citation
Rossetto, Monica; Vanzani, Paola; De Marco, Veronica; Zennaro, Lucio; Scarpa, Marina; Rigo, Adelio
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 10 p. 3486 - 3492 Title/Abstract Full Text View citing articles Show Details
Effect
Antiviral
Assay Description
Effect : virucidal Species : P22 bacteriophage host bacteria for title comp.-treated species: Salmonella typhimurium
Citation
Giao, Maria S.; Borges, Andre B.; Guedes, Catarina J.; Hogg, Tim A.; Pintado, Manuela E.; Malcata, F. Xavier
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 1 p. 22 - 25 Title/Abstract Full Text View citing articles Show Details
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Effect
Antibiotic
Biological material
Listeria monocytogenes
Assay Description
Effect : antilisterial Species : Listeria monocytogenes Scott A conductance method
Results
detection time 9.5 - 14.9 h
Citation
Anastasiadi, Maria; Chorianopoulos, Nikos G.; Nychas, George-John E.; Karoutounian, Serkos A.
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 2 p. 457 - 463 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Biological material
Listeria monocytogenes
Assay Description
Effect : antilisterial Species : Listeria monocytogenes Scott A count technique
Results
final viable count <1-8.75 log(CFU/ml)
Citation
Anastasiadi, Maria; Chorianopoulos, Nikos G.; Nychas, George-John E.; Karoutounian, Serkos A.
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 2 p. 457 - 463 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : radical scavenging Bioassay : 1,1'-diphenyl-2-picrylhydrazyl
Results
SC50 scavenging concentration 15.4 μmol/l
Citation
Liu, Qing; Zhang, Ying-Tun; Yang, Chong-Ren; Xu, Mei
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 2 p. 586 - 590 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : 2,2-azobis(2-amidinopropane hydrochloride) TE: Trolox equivalents; test system as a solution used
Results
ORACFL oxygen radical absorbance capacity 8.22 μmol TE/ml
Citation
Alamed, Jean; Chaiyasit, Wilailuk; McClements, D. Julian; Decker, Eric A.
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2969 - 2976 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : protein expression Target : ;catalase Bioassay : colorectal adenoma LT97 cells
Citation
Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details
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Biological material
human
Assay Description
Effect : protein expression Target : ;superoxide dismutase Bioassay : colorectal adenoma LT97 cells
Citation
Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : DNA damage Bioassay : colorectal adenoma LT97 cells
Citation
Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : enzyme activity Target : ;catalase Bioassay : colorectal adenoma LT97 cells
Citation
Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : enzyme activity Target : ;superoxide dismutase Bioassay : colorectal adenoma LT97 cells
Citation
Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human
Assay Description
Effect : LDH release Target : HPV Bioassay : prostate epithelial PZ-7 cells
Citation
Chen, Kuan-Chou; Hsieh, Chiu-Lan; Huang, Kuan-Dar; Ker, Yaw-Bee; Chyau, Charng-Cherng; Peng, Robert Y.
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 14 p. 6114 - 6122 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human NCI-H460 cell line
Assay Description
Effect : cell cycle PDP value is concentration-dependent
Results
percent cells in G2-M phase 26.98 - 36.06 %
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Citation
Bin-Chuan; Hsu, Wu-Huei; Yang, Jai-Sing; Hsia, Te-Chun; Lu, Chi-Cheng; Chiang, Jo-Hua; Yang, Jiun-Long; Lin, Ching-Hsiung; Jen-jyh; Lee-jen, Wu Suen; Wellington, Gibson Wood; Chung, Jing-Gung
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 16 p. 7596 - 7604 Title/Abstract Full Text View citing articles Show Details
Effect
Cardioprotective
Biological material
Rattus norvegicus
Assay Description
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Results
title comp. significantly improved contractile function during reperfusion
Citation
Yamashiro, Satoshi; Noguchi, Katsuhiko; Matsuzaki, Toshihiro; Miyagi, Kanako; Nakasone, Junko; Sakanashi, Mayuko; Sakanashi, Makiko; Kukita, Ichiro; Aniya, Yoko; Sakanashi, Matao
Pharmacology, 2003 , vol. 67, # 3 p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
Target
cytokine:Wild
Assay Description
Effect : cytokine production; inhibition of Bioassay : MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; control: without title comp. and without DSS (IL-1β level 1.37 pg/ml), without title comp. (IL-1β level 103 pg/ml); DSS: dextran sulfate sodium test cells incubated with title comp. in Dulbecco's Modified Eagle Medium at 37 deg C for 30 min in 5 percent humidified CO2 atmosphere; 1 μg/ml DSS added and incubated for 12 h; IL-1β level in medium supernatant measured with ELISA
Results
title comp. caused decrease of IL-1β level to 91.7 and 36.4 pg/ml at 20 and 100 μmol/l, respectively
Citation
Kwon, Ki Han; Murakami, Akira; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 2 p. 436 - 439 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : radical scavenging activity Bioassay : DPPH radical DPPH:1,1-diphenyl-2-picrylhydrazyl; SC50: concentration necessary for 50% reduction of DPPH radical
Results
SC50 13.5 μmol/l
Citation
Gao, Da-Fang; Xu, Min; Yang, Chong-Ren; Xu, Mei; Zhang, Ying-Jun
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 15 p. 8820 - 8824 Title/Abstract Full Text View citing articles Show Details
Effect
Mitogenic
Assay Description
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Bioassay : metabolic changes further studied isolated hearts subjected to 30 min global ischemia at 37 deg C followed by 20-min reperfusion; left ventricular function studied
Target : BAF/IL10R cells Bioassay : cell proliferation activity evaluated; 1E5 cells/well; humidified 5 percent CO2 in air; 37 deg C; incubated for 24 h; cell proliferation measured by colorimetric 2-(4-iodophenyl)-3-(4nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium-based assay
Results
title comp. showed conc.-dependent IL-10-like proliferation activity with max. at 30 μg/ml
Citation
Nishimura, Tadahiro; Wang, Li-Yan; Kusano, Kouji; Kitanaka, Susumu
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 3 p. 305 - 308 Title/Abstract Full Text View citing articles Show Details
Effect
Mitogenic
Assay Description
Target : BAF/InsR cells Bioassay : cell proliferation activity evaluated; 1E5 cells/well; humidified 5 percent CO2 in air; 37 deg C; incubated for 24 h; cell proliferation measured by colorimetric 2-(4-iodophenyl)-3-(4-
nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium-based assay
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Citation
Nishimura, Tadahiro; Wang, Li-Yan; Kusano, Kouji; Kitanaka, Susumu
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 3 p. 305 - 308 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Biological material
human Hep G2
Assay Description
Effect : |enzyme; induction of Bioassay : DMEM with 10 percent FBS; humidified atmosphere of 95 percent air and 5 percent CO2; 37 deg C; incubated for 24 h; induction of P-form phenolsulfotransferase activity assayed
Results
title comp. induced enzyme activity in conc.-dependent manner with maximum of 4-5-fold induction
Citation
Yeh, Chi-Tai; Huang, Shang-Ming; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 12 p. 4766 - 4773 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Biological material
human Hep G2
Assay Description
Effect : |enzyme; induction of Bioassay : DMEM with 10 percent FBS; humidified atmosphere of 95 percent air and 5 percent CO2; 37 deg C; incubated for 3-24 h; induction of P-form phenolsulfotransferase (PST-P) mRNA expression and protein translation determined by RT-PCR and Western blot analysis, respectively
Results
title comp. induced P-PST mRNA expression and protein translation in conc.- and time-dependent manner
Citation
Yeh, Chi-Tai; Huang, Shang-Ming; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 12 p. 4766 - 4773 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human Hep G2
Assay Description
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Results
at 50 μmol/l title comp. inhibited cell growth by 6 percent
Citation
Yeh, Chi-Tai; Huang, Shang-Ming; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 12 p. 4766 - 4773 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human Hep G2
Assay Description
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Bioassay : DMEM with 10 percent FBS; humidified atmosphere of 95 percent air and 5 percent CO2; 37 deg C; incubated for 24 h; cell viability determined with 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide colorimetric assay
Bioassay : DMEM with 10 percent FBS; humidified atmosphere of 95 percent air and 5 percent CO2; 37 deg C; incubated for 24 h; cell viability determined with lactate dehydrogenase assay
Citation
Yeh, Chi-Tai; Huang, Shang-Ming; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 12 p. 4766 - 4773 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
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Biological material
Rattus norvegicus
Assay Description
Effect : |enzyme; inhib. of Bioassay : sodium azide (250 μmol/l) as reference completely inhibited enzyme activity myeloperoxidase studied; title comp. used in reaction medium with 50 mmol/l NaH2PO4, 0.167 mg/ml τ-dianisidine and 0.0005 percent H2O2 at 25 deg C; enzyme activity measured spectrophotometrically at 450 nm; control without title comp.
Results
K0.5 28.7 μmol/l
Citation
Rosso, Rober; Vieira, Tiago O.; Leal, Paulo C.; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 18 p. 6409 - 6413 Title/Abstract Full Text View citing articles Show Details
Effect
Hepatotoxic
Biological material
Rattus norvegicus
Assay Description
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Bioassay : liver slices incubated with title comp. for 1 h at 37 deg C in HEPES; cell viability determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide-formazan assay; optical density measured at 550 nm; control without title comp.
Citation
Rosso, Rober; Vieira, Tiago O.; Leal, Paulo C.; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 18 p. 6409 - 6413 Title/Abstract Full Text View citing articles Show Details
Effect
Antihistaminic
Biological material
Rattus norvegicus mast cell
Assay Description
Effect : 48/80 compound - induced histamine release
Citation
Bao, Li; Yao, Xinsheng; Xu, Jiekun; Guo, Xiaoyu; Liu, Hongwei; Kurihara, Hiroshi
Fitoterapia, 2009 , vol. 80, # 6 p. 349 - 353 Title/Abstract Full Text View citing articles Show Details
Target
P-selectin [human]:Wild
Assay Description
Effect : E-selectin binding; inhibition of Bioassay : Competition assay of gallic acid (derivatives) and polyphenols with PAA-Lea-SO3H To be able to test gallic acid binding also to other members of the selectin family (i.e. E- and L-selectin), biotin-PAA-Lea-SO3H (Synthesone, Munich, Germany) instead of TM11-PO was used as ligand in the competition
Citation
YAMANOUCHI PHARMACEUTICAL CO. LTD.
Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details
Biological material
human HL-60 cell line
Assay Description
Effect : cell interaction; inhibition of Bioassay : Inhibition of dynamic interactions between HL60 cells and human P-selectin expressing Chinese hamster ovary cells Chinese hamster ovary (CHO) cells stably transfected with human P-selectin (CHO-P) were kindly donated by Dr. Modderman (University of Amsterdam, Amsterdam, the Netherlands). Cells
Results
significantly decreased HL60 cell adhesion to the CHO-P monolayer at 50 &micro;M irrespective of the wall shear rates; at 250 &micro;M, the effect was even more pronounced (-41 % and -54% respectively); The rolling velocity of the HL60 cells rolling
Citation
YAMANOUCHI PHARMACEUTICAL CO. LTD.
Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details
Assay Description
Effect : |drug interaction Target : phreochromocytoma PC12 cells of rat Bioassay : Materials and Methods Dexamethasone, L-glutamate and all test agents were obtained from Sigma (except Pycnogenol which was obtained from Nature's Aid, Preston, UK) and initially dissolved in ETOH to make 10 mM stock solutions. These were then used to prepare experimental concentrations. 1: 1000
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Results
title comp. and quercetin induced dose-dependent synergistic reduction of prostaglandin E2 and leukotriene B4 levels
Citation
UNILEVER PLC; UNILEVER NV; HINDUSTAN LEVER LIMITED
Patent: WO2005/67915 A1, 2005 ; Title/Abstract Full Text Show Details
Biological material
Lemna paucicostata
Assay Description
Effect : plant growth; inhibition of Bioassay : Example 4 Evaluation on the Efficacy of Natural Compounds In order to investigate the growth inhibiting activity to Marchantia polymorpha L. photomixotrophic cells of natural compounds isolated from various plants (Table 3), the present inventors performed the efficacy evaluation test used in the above
Citation
Korea Research Institute of Bioscience and Biotechnology
Patent: US2005/176584 A1, 2005 ; Title/Abstract Full Text Show Details
Effect
Antiproliferative
Assay Description
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Results
title compound provides inhibition activity 8 % at 1 ppm
Citation
Korea Research Institute of Bioscience and Biotechnology
Patent: US2005/176584 A1, 2005 ; Title/Abstract Full Text Show Details
Results
inhibitory activity against Staphylococcus aureus NCTC6571, Pseudomonas aeruginosa NCTC6750, Escherichia coli NCTC8545, and Bacillus subtilis NCTC7801
Citation
Richards; Durham; Liu
Planta Medica, 1994 , vol. 60, # 5 p. 471 - 473 Title/Abstract Full Text View citing articles Show Details
Results
moderate mutagenicity on Salmonella typhimurium TA 100
Citation
Yamaguchi, Tsutomu
Agricultural and Biological Chemistry, 1981 , vol. 45, # 1 p. 327 - 330 Title/Abstract Full Text Show Details
Effect
Antioxidant
Biological material
human fibroblast
Assay Description
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Target : photomixotrophic cells of Marchantia polymorpha L. Bioassay : Example 4 Evaluation on the Efficacy of Natural Compounds In order to investigate the growth inhibiting activity to Marchantia polymorpha L. photomixotrophic cells of natural compounds isolated from various plants (Table 3), the present inventors performed the efficacy evaluation test used in the above
Bioassay : survival analysis (survival as percentage for survival of the control cells) cell cultivation for 1 d; exposure to 1 mM H2O2 for 2 h in the presence of title comp.; neutral red method
Results
title comp. strongly inhibited H2O2-induced cell damage (table given)
Citation
Masaki, Hitoshi; Okamoto, Nobuo; Sakaki, Sachiko; Sakurai, Hiromu
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 304 - 308 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
human fibroblast
Assay Description
Bioassay : survival analysis (survival as percentage for survival of the control cells) cell cultivation for 1 d; title comp. treatment for 24 h; washing with Hanks balanced salt solution; exposure to 1 mM
H2O2 for 2 h; neutral red method
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Citation
Masaki, Hitoshi; Okamoto, Nobuo; Sakaki, Sachiko; Sakurai, Hiromu
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 304 - 308 Title/Abstract Full Text View citing articles Show Details
Results
no acetyl-CoA carboxylase inhibitory activity
Citation
Watanabe; Kawabata; Niki
Bioscience, biotechnology, and biochemistry, 1998 , vol. 62, # 3 p. 532 - 534 Title/Abstract Full Text View citing articles Show Details
Results
weakly active according to NCCLS recommendations (MIC: <μg/ml>) against Candida albicans ATCC 14053 (500), Cryptococcus neoformans KF-33 (250), Saccharomyces cerevisiae PLM 454 (1000)
Citation
Sardari; Able; Micetich; Daneshtalab
Pharmazie, 1999 , vol. 54, # 2 p. 156 - 158 Title/Abstract Full Text View citing articles Show Details
Results
affinity for lipid bilayers evaluated with egg PC liposome system
Citation
Nakayama; Ono; Hashimoto
Bioscience, biotechnology, and biochemistry, 1998 , vol. 62, # 5 p. 1005 - 1007 Title/Abstract Full Text Show Details
Results
inhibitory activity against rat lens aldose reductase (AR) IC50 >100 μM
Citation
Terashima; Shimizu; Horie; Morita
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 12 p. 3346 - 3347 Title/Abstract Full Text View citing articles Show Details
Biological material
human smooth muscle cell
Assay Description
Effect : cholesterol efflux; stimulatory effect on Bioassay : Figure 10 is a graph showing the effect of active compounds from EO on efflux of cholesterol in human aortic smooth muscle cells. Confluent culture of H- ASMC in 96 well plates was incubated with [3H] cholesterol (5 μCi/ml) for 24 h. Medium was replaced with fresh medium and incubation with herbal
Results
title compound significantly induced efflux of cholesterol from cells; figure is given
Citation
THE JOHNS HOPKINS UNIVERSITY; MERLION PHARMACEUTICAL PTC LTD
Patent: WO2008/80162 A2, 2008 ; Title/Abstract Full Text Show Details
Biological material
human smooth muscle cell
Assay Description
Effect : cholesterol uptake; inhibition of Bioassay : Figure 11 is a graph showing the effect of active compounds from EO on uptake of cholesterol in human aortic smooth muscle cells. Confluent culture of cells grown in 96 well plates was incubated in serum- free medium with [3H] cholesterol (5 μCi/ml) with and without active fractions. After 24 h the
Results
title compound markedly inhibited cholesterol uptake in cells; figure is given
Citation
THE JOHNS HOPKINS UNIVERSITY; MERLION PHARMACEUTICAL PTC LTD
Patent: WO2008/80162 A2, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Bioassay : samples collected; activated carbon (PACV) equilibrated with title comp.; UV-visible spectrophotometer at 212 nm, at 27 deg C; adsorption isotherm fitted to Freundlich, Langmuir and DubininRadushkevich equations
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Results
adsorption Freundlich constant (KF): 0.32 mg/g; table; figure
Citation
Figaro; Louisy-Louis; Lambert; Ehrhardt; Ouensanga; Gaspard
Water Research, 2006 , vol. 40, # 18 p. 3456 - 3466 Title/Abstract Full Text View citing articles Show Details
Assay Description
Results
adsorption Freundlich constant (KF): 51.35 mg/g; Langmuir constant (KL): 0.030 l/mg; maximum adsorption of title comp. in micropore (QDR): 598 mg/g; table; figure
Citation
Figaro; Louisy-Louis; Lambert; Ehrhardt; Ouensanga; Gaspard
Water Research, 2006 , vol. 40, # 18 p. 3456 - 3466 Title/Abstract Full Text View citing articles Show Details
Assay Description
adsorption Freundlich constant (KF): 76.0 mg/g; Langmuir constant (KL): 0.08 l/mg; maximum adsorption of title comp. in micropore (QDR): 515 mg/g; table; figure
Citation
Figaro; Louisy-Louis; Lambert; Ehrhardt; Ouensanga; Gaspard
Water Research, 2006 , vol. 40, # 18 p. 3456 - 3466 Title/Abstract Full Text View citing articles Show Details
Effect
Inotropic : Negative
Target : guinea pig atria Bioassay : left and right atria mounted separately in tissue bath (Krebs' solution, 32 deg C), left atria stimulated with rectangular pulses; after equilibration period, title comp. added; tension changes recorded via a Grass force-displacement transducer
Citation
Ghayur; Gilani, Anwarul Hassan
Pharmazie, 2007 , vol. 62, # 1 p. 67 - 71 Title/Abstract Full Text View citing articles Show Details
Effect
Spasmogenic
Biological material
rabbit
Assay Description
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Bioassay : samples collected; activated carbon (PAC6) equilibrated with title comp.; UV-visible spectrophotometer at 212 nm, at 27 deg C; adsorption isotherm fitted to Freundlich, Langmuir and DubininRadushkevich equations
Results
Assay Description
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Bioassay : samples collected; activated carbon (PAC5) equilibrated with title comp.; UV-visible spectrophotometer at 212 nm, at 27 deg C; adsorption isotherm fitted to Freundlich, Langmuir and DubininRadushkevich equations
Bioassay : jejunum mounted in tissue bath (Tyrode's solution, 37 deg C), preload of 1 g applied; after equilibration period (30 min), title comp. added; tension changes in tissue recorded via a Grass forcedisplacement transducer
Citation
Ghayur; Gilani, Anwarul Hassan
Pharmazie, 2007 , vol. 62, # 1 p. 67 - 71 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : antibiotic resistance; effect on Target : Staphylococcus aureus OM584 Bioassay : OM584 strain: methicillin-resistant clinical isolate from Okayama University Hospital; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined
Results
title comp. decreased oxacillin MIC from 256 to 32 μg/ml
Citation
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
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Assay Description
Effect : antibiotic resistance; inhibition of Target : Staphylococcus aureus OM481 Bioassay : OM481 strain: methicillin-resistant clinical isolate from Okayama University Hospital; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined
Results
title comp. decreased MIC of oxacillin from 256 to 2 μg/ml
Citation
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : antibiotic resistance; inhibition of Target : Staphylococcus aureus OM505 Bioassay : OM505 strain: methicillin-resistant clinical isolate from Okayama University Hospital; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined
Results
title comp. decreased oxacillin MIC from 64 to 32 μg/ml
Citation
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : antibiotic resistance; inhibition of Target : Staphylococcus aureus OM623 Bioassay : OM623 strain: methicillin-resistant clinical isolate from Okayama University Hospital; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined
Results
in presence of title comp. oxacillin MIC decreased from 256 to 64 μg/ml
Citation
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : antibiotic resistance; effect on Target : Staphylococcus aureus 209P Bioassay : 209P strain: methicillin-sensitive; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined
Citation
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |protein binding Target : B14 Chinese hamster fibroblast cells Bioassay : control cells treated with phosphate buffer saline (pH 7.4) or Cu(2+) or H2O2; two replicates cells incubated with title comp. with/without Cu(2+) (50μmol/l) or H2O2 (10 μmol/l) for 1 h at 5 deg C; carbonyl groups assayed by method based on use of 2,4-dinitrophenylhydrazine (dissolved in 2M HCl) by spectrophotometricaly (at 370 nm)
Results
title comp. significantly increased carbonyl groups in cells in dose-dependent manner; presence of Cu(2+) or H2O2 intensify effect of title comp. and increased carbonyl groups in cells (histograms)
Citation
Labieniec, Magdalena; Gabryelak, Teresa
Toxicology Letters, 2005 , vol. 155, # 1 p. 15 - 25 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
Target : B14 Chinese hamster fibroblast cells Bioassay : control cells treated with phosphate buffer saline with pH 7.4 (PBS) Trypan blue exclusion assay: cells incubated with title comp. for 1-24 h at 5 deg C; then cells rinsed in PBS and resuspended in 0.4 percent Trypan blue dye; cell viability calculated as percent ratio of referent control
Results
title comp. caused reduction in viability of digestive gland cells in conc.-dependent manner but cell viability was >70 percent (table)
Citation
Labieniec, Magdalena; Gabryelak, Teresa
Toxicology Letters, 2005 , vol. 155, # 1 p. 15 - 25
Title/Abstract Full Text View citing articles Show Details
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Effect Assay Description
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title comp. demonstrated genotoxic effect and contribute to DNA damage at 15 and 60 μmol/l, at 1 μmol/l title comp. did not caused strand breaks in DNA; Cu(2+) or H2O2 intensify effect of title comp. exclude at 60 μmol/l with H2O2 (histograms)
Citation
Labieniec, Magdalena; Gabryelak, Teresa
Toxicology Letters, 2005 , vol. 155, # 1 p. 15 - 25 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
Oncorhynchus mykiss erythrocyte
title comp. exerted protective effect at 1 and 5 μmol/l; diagram
Citation
Fedeli, Donatella; Berrettini, Marco; Gabryelak, Teresa; Falcioni, Giancarlo
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 563, # 2 p. 89 - 96 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
Oncorhynchus mykiss erythrocyte
Bioassay : RBCs: red blood cells RBCs suspended (2E6 RBCs/ml); CO-saturated erythrocytes or cells exposed to air incubated with title comp. at 35 deg C, pH 6.3; t1/2 of hemolysis determined spectrophotometrically at 540 nm
Citation
Fedeli, Donatella; Berrettini, Marco; Gabryelak, Teresa; Falcioni, Giancarlo
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 563, # 2 p. 89 - 96 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Biological material
Oncorhynchus mykiss erythrocyte
Assay Description
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Bioassay : tail moment: index of DNA damage; considers extent of DNA migration in comet tail and fluorescence intensity of genetic material migrated out from comet head in comet tail cells (1E6 cells/ml) incubated with title comp. for 1 h at pH 6.3 and 35 deg C (oxidative stress conditions); cells embedded in agarose, followed by lysis, electrophoresis and staining (comet assay); fluorescence microscopy; tail moment determined
Results
Assay Description
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Target : B14 Chinese hamster fibroblast cells Bioassay : control cells treated with phosphate buffer saline (pH 7.4) or Cu(2+) or H2O2 cells incubated with title comp. with/without Cu(2+) (50μmol/l) or H2O2 (40 μmol/l) for 1 h at 5 deg C; cells fixed on 0.5 percent normal melting-point agarose and lysed; comet tail moment determined by single-cell gel electrophoresis (comet assay)
Results
Assay Description
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Genotoxic
Bioassay : reference: H2O2 (5 μmol/l); tail moment: index of DNA damage; considers extent of DNA migration in comet tail and fluorescence intensity of genetic material migrated out from comet head in comet tail erythrocytes incubated with title comp. for 1 h at pH 7.8 and 4 deg C; cells embedded in agarose, followed by lysis, electrophoresis and staining (comet assay); fluorescence microscopy; tail moment determined
Results
presence of 10 μmol/l of title comp. increased DNA damage to same extent as H2O2; diagram
Citation
Fedeli, Donatella; Berrettini, Marco; Gabryelak, Teresa; Falcioni, Giancarlo
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 563, # 2 p. 89 - 96 Title/Abstract Full Text View citing articles Show Details
Effect
Proliferative
Assay Description
Target : Sea/ddy mouse hair epithelial cells Bioassay : proliferation quantified using <3H>thymidine incorporation method (24 h incubation, 37 deg C, 5 percent CO2); liquid scintillation counting; minoxidil (70 μg/ml, 140 percent of control) used as reference compound in vitro; cell suspension plated on collagen-coated plates and incubated in DMEM with 5 percent FBS at 37 deg C under 5 percent CO2 atmosphere for 24 h; cells washed with PBS and incubated with title comp. in MCDB153 for 4 h
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Results
title comp. stimulated proliferation of epithelial cells only at 1 and 10 μmol/l doses giving ca. 135 percent and ca. 150 percent of control, respectively
Citation
Towatari, Keisuke; Yoshida, Kiyo; Mori, Nobuhiro; Shimizu, Kuniyoshi; Kondo, Ryuichiro; Sakai, Kokki
Planta Medica, 2002 , vol. 68, # 11 p. 995 - 998 Title/Abstract Full Text View citing articles Show Details
Effect
Proliferative
Assay Description
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Results
title comp. stimulated cell proliferation reaching ca. 135 percent of control in MTT assay and ca. 145 percent according to cell count
Citation
Towatari, Keisuke; Yoshida, Kiyo; Mori, Nobuhiro; Shimizu, Kuniyoshi; Kondo, Ryuichiro; Sakai, Kokki
Planta Medica, 2002 , vol. 68, # 11 p. 995 - 998 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; induction of Bioassay : MGST: microsomal glutathione S-transferase; CDNB: 1-chloro-2,4-dinitrobenzene; GSH: reduced glutathione; further investigation in the presence of SOD (superoxide dismutase), catalase, reducing agents, redial scavengers microsomes incubated with title comp. in phosphate buffer (pH 7.4) at 30 deg C for 5 min; MGST1 activity measured using CDNB and GSH as substrates
Results
title comp. dose-dependently increased MGST1 activity acting through oxidative modification of enzyme (diagram)
Citation
Shinno, Etsuki; Shimoji, Miyuki; Imaizumi, Naoki; Kinoshita, Shizuka; Sunakawa, Hajime; Aniya, Yoko
Life Sciences, 2005 , vol. 78, # 1 p. 99 - 106 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; induction of Bioassay : MGST: microsomal glutathione S-transferase; GSH: reduced glutathione; CDNB: 1-chloro-2,4-dinitrobenzene GSH-free purified MGST1 incubated with title comp. in phosphate buffer (pH 7.4) at 30 deg C for 5 min; MGST1 activity measured using CDNB and GSH as substrates
Results
title comp. dose-dependently increased MGST1 activity (850 percent of control at 0.5 mmol/l) (diagram)
Citation
Shinno, Etsuki; Shimoji, Miyuki; Imaizumi, Naoki; Kinoshita, Shizuka; Sunakawa, Hajime; Aniya, Yoko
Life Sciences, 2005 , vol. 78, # 1 p. 99 - 106 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Target : Sea/ddy mouse hair epithelial cells Bioassay : viability of cells determined at day 5 by MTT assay and at day 6 by cell count in vitro; cell suspension plated on collagen-coated plates and incubated in DMEM with 5 percent FBS at 37 deg C under 5 percent CO2 atmosphere for 24 h; cells washed with PBS and incubated with title comp. in MCDB153 for 5 or 6 d
Target : Sprague-Dawley rat liver microsomes Bioassay : CL: chemiluminescence microsomes incubated with title comp. in the presence of NADPH generating system in phosphate buffer (pH 7.4); CL counted for 5 min
Results
title comp. decreased CL production (diagram)
Citation
Shinno, Etsuki; Shimoji, Miyuki; Imaizumi, Naoki; Kinoshita, Shizuka; Sunakawa, Hajime; Aniya, Yoko
Life Sciences, 2005 , vol. 78, # 1 p. 99 - 106 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |biotransformation Target : Erwinia rhapontici SL-3
Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography
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Citation
Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |biotransformation Target : Klebsiella terrigena SL-2 Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography
Citation
Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |biotransformation Target : Pantoea agglomerans SL-1 Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography
Citation
Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |biotransformation Target : Rahnella aquatilis ML-1 Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography
Citation
Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |biotransformation Target : Rahnella aquatilis YL-1 Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography
Citation
Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details
Effect
Antifungal
Assay Description
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Target : Pytium ultimum Bioassay : potato-dectrose agar test; 2 day incubation at 25 deg C in dark
Results
illustrative representation of antifungal activity
Citation
Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details
Results
utilization as substrate by Citrobacter sp., strain 64-1 at 0.2percent (28 deg C, 24 h)
Citation
Yoshida, Hajime; Tani, Yoshiki; Yamada, Hideaki
Agricultural and Biological Chemistry, 1982 , vol. 46, # 10 p. 2539 - 2546 Title/Abstract Full Text Show Details
Effect
Antioxidant
Assay Description
Target : human plasma low density lipoprotein
Bioassay : TBARS levels in intact/UVB irradiated low density lipoprotein: 0.028/0.720 nmol malonaldehyde/mg protein plasma from fresh blood obtained from healthy adults; PBS, pH 7.4; incubated for 30 min; treated by UVB (280-350 nm) for up to 480 min; thiobarbituric acid reactive substances (TBARS) and relative electrophoretic mobility (REM) determined
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Results
at 10/100 μmol/l title comp. significantly decreased TBARS level induced by UVB irradiation (to 0.365/0.203 nmol malonaldehyde/mg protein); at 100 μmol/l title comp. did not change REM of low density lipoprotein
Citation
Hsieh, Chiu-Lan; Yen, Gow-Chin; Chen, Hui-Yin
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 15 p. 6151 - 6155 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
human erythrocyte
Assay Description
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Bioassay : HFG: hemoglobin-free ghost; GSH: glutathione; TBARS: thiobarbituric acid reactive substances; GPx: glutathione peroxidase cells from fresh blood obtained from healthy adults; PBS; incubated for 4 h; treated by UVB (280-350 nm) for 30-120 min; HFG and hemolysate prepared; GSH content and TBARS in HFG and GSH content and intracellular activities in hemolysate measured
Results
title comp. reduced UVB-induced oxidative damage (decreased TBARS formation in conc.-dependent manner, prevented GSH loss, inhibited GPx inactivity)
Citation
Hsieh, Chiu-Lan; Yen, Gow-Chin; Chen, Hui-Yin
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 15 p. 6151 - 6155 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : DP binding protein binding affinity Bioassay : serum albumin A3782 circular dichroism study; DP: diazepam
Citation
Nozaki, Akiko; Kimura, Toshikiro; Ito, Hideyuki; Hatano, Tsutomu
Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 9 p. 1019 - 1023 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : PB binding protein binding affinity Bioassay : serum albumin A3782 circular dichroism study; PB: phenylbutazone
Citation
Nozaki, Akiko; Kimura, Toshikiro; Ito, Hideyuki; Hatano, Tsutomu
Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 9 p. 1019 - 1023 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : hypoxanthine/xanthine oxidase HPLC; DHBA production was determined
Citation
Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.
Food Chemistry, 2012 , vol. 133, # 3 p. 697 - 706 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : oxygen radical ORAC: oxygen reducing absorbance capacity; 1 ORAC unit equals the inhibition of the declining fluorescence produced by 1 μmol/l of trolox
Results
ORAC 1.18 units
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Citation
Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.
Food Chemistry, 2012 , vol. 133, # 3 p. 697 - 706 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
human Hep G2
Assay Description
Effect : peroxyl radical-induced DCFH oxidation DCFH: 2',7'-dichlorofluorescin; QE: quercetin; peroxyl radicals generated from ABAP (2,2'-azobis(2-amidinopropane)); cells washed with PBS between antioxidant and ABAP treatment
Results
CAA cellular antioxidant activity 1.53 μmol QE/100 μmol
Citation
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
human Hep G2
Assay Description
Effect : peroxyl radical-induced DCFH oxidation DCFH: 2',7'-dichlorofluorescin; QE: quercetin; peroxyl radicals generated from ABAP (2,2'-azobis(2-amidinopropane)); no PBS wash between antioxidant and ABAP treatment
Results
CAA cellular antioxidant activity 9.08 μmol QE/100 μmol
Citation
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
Effect
Anti-Atherogenis
Biological material
Mus musculus
Assay Description
Effect : cellular oxidative stress Bioassay : J774 A.1 macrophage
Results
cellular oxidative stress reduction 30 %
Citation
Aviram, Michael; Volkova, Nina; Dreher, Mark; Rosenblat, Mira; Coleman, Raymond; Reddy, Muntha Kesava; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 3 p. 1148 - 1157 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidant Bioassay : 2,2'-azobis(2-methylpropionamidine) dihydrochloride ORAC: oxygen radical absorbance capacity; 1 ORAC unit equals the inhibition of the declining fluorescence produced by 1 μmol/l Trolox
Results
IC inhibitory concentration 1.94
Citation
Barreto, Jacqueline C.; Trevisan, Maria T. S.; Hull, William E.; Erben, Gerhard; De Brito, Edy S.; Pfundstein, Beate; Wuertele, Gerd; Spiegelhalder, Bertold; Owen, Robert W.
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 14 p. 5599 - 5610 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : DPPH radical Target : DPPH radical Bioassay : 1,1-diphenyl-2-picrylhydrazyl radical SC50: concentration of title comp. necessary for 50% reduction of DPPH radical
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Results
SC50 13 μmol/l
Citation
Gao, Da-Fang; Zhang, Ying-Jun; Yang, Chong-Ren; Chen, Ke-Ke; Jiang, Hong-Jian
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 16 p. 7517 - 7521 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : antioxidative Bioassay : 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid radical cation
Results
TEAC Trolox equivalent antioxidant capacity 2.6
Citation
Walker, Richard B.; Everette, Jace D.
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 4 p. 1156 - 1161 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
human
Assay Description
Effect : Cu2+-induced diene conjugation Bioassay : blood low density lipoprotein LDL: low-density lipoprotein; δTlag: is lag phase of LDL oxidation between title comp. treated group and CuSo4-treated group
Results
δTlag > 12 h
Citation
Huang, Din-Wen; Kuo, Yueh-Hsiung; Lin, Fang-Yi; Lin, Yun-Lian; Chiang, Wenchang
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 6 p. 2259 - 2266 Title/Abstract Full Text View citing articles Show Details
Biological material
Escherichia coli
Assay Description
Effect : ATP hydrolysis activity enzyme activity Target : hepatitis C virus NS3h helicase Species : Escherichia coli BL21(DE3) colorimetry-based ATP hydrolysis assay
Citation
Yu, Mi-Sun; Lee, June; Lee, Jin Moo; Kim, Younggyu; Chin, Young-Won; Jee, Jun-Goo; Keum, Young-Sam; Jeong, Yong-Joo
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4049 - 4054 Title/Abstract Full Text View citing articles Show Details
Biological material
Escherichia coli
Assay Description
Effect : dsDNA unwinding activity enzyme activity Target : SARS CoV nsP13 helicase Species : Escherichia coli Rosetta fluorescence resonance energy transfer (FRET)-based double-strand (ds) DNA unwinding assay; SARS CoV: severe acute respiratory syndrome coronavirus
Citation
Yu, Mi-Sun; Lee, June; Lee, Jin Moo; Kim, Younggyu; Chin, Young-Won; Jee, Jun-Goo; Keum, Young-Sam; Jeong, Yong-Joo
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4049 - 4054 Title/Abstract Full Text View citing articles Show Details
Biological material
Escherichia coli
Assay Description
Effect : dsDNA unwinding activity enzyme activity Target : hepatitis C virus NS3h helicase Species : Escherichia coli BL21(DE3) fluorescence resonance energy transfer (FRET)-based double-strand (ds) DNA unwinding assay
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Citation
Yu, Mi-Sun; Lee, June; Lee, Jin Moo; Kim, Younggyu; Chin, Young-Won; Jee, Jun-Goo; Keum, Young-Sam; Jeong, Yong-Joo
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4049 - 4054 Title/Abstract Full Text View citing articles Show Details
Effect
Mutagenic
Assay Description
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Citation
Martinez, A.; Urios, A.; Blanco, M.
Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details
Effect
Mutagenic
Assay Description
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oxidative mutagenesis in the abs. of S9 mix; mutagenesis inhibited by S9
Citation
Martinez, A.; Urios, A.; Blanco, M.
Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details
Effect
Mutagenic
Martinez, A.; Urios, A.; Blanco, M.
Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details
Effect
Mutagenic
Target : Escherichia coli IC208 Bioassay : mutY oxyR WP2 uvrA/pKM101 bacterial strain in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; number of revertants per plates counted
Citation
Martinez, A.; Urios, A.; Blanco, M.
Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details
Effect
Mutagenic
Assay Description
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Target : Escherichia coli IC206 Bioassay : mutY WP2 uvrA/pKM101 bacterial strain in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; number of revertants per plates counted
Citation
Assay Description
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Target : Escherichia coli IC203 Bioassay : WP2 uvrA/pKM101 bacterial strain deficient in OxyR in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; with and without metabolic activation with S9 mix; number of revertants per plates counted
Results
Assay Description
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Target : Escherichia coli IC188 Bioassay : parent WP2 uvrA/pKM101 bacterial strain in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; number of revertants per plates counted
Target : Escherichia coli IC204 Bioassay : mut+ WP2 uvrA/pKM101 bacterial strain in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; number of revertants per plates counted
Citation
Martinez, A.; Urios, A.; Blanco, M.
Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details
Effect
Antimicrobial
Assay Description
Target : ATCC 10231 of Candida albicans
Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms
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Results
title compound was found to be selective inhibitor of Candida albicans and zone of inhibition amount 5-4 mm at 1 - 10 mg/ml
Citation
Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.
Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details
Effect
Antimicrobial
Assay Description
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Citation
Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.
Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details
Effect
Antimicrobial
Assay Description
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Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.
Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details
Effect
Antimicrobial
Target : ATCC 6538 of Staphylococcus aureus Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms
Citation
Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.
Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details
Effect
Antimicrobial
Assay Description
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Target : ATCC 11975 of Lactobacillus acidophilus Bioassay : C. albicans is an opportunistic organism that can cause various infections of the skin, mouth and vagina. C. albicans and other Candida strains are part of normal human microbial flora, but under certain circumstances may cause complications, such as infection. The challenge to the medical field is
Citation
Assay Description
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Target : ATCC 16404 of Aspergillus niger Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms
Target : ATCC 8739 of Escherichia coli Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms
Citation
Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.
Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details
Effect
Antimicrobial
Assay Description
Citation
Target : ATCC 9027 of Pseudomonas aeruginosa Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.
Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details
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Biological material
Calloselasma rhodostoma
Assay Description
Effect : fibrinogenolytic activity anti-snake venom metalloproteinase activity Bioassay : venom
Results
complete inhibition concentration 14.11 μmol/l
Citation
Pithayanukul, Pimolpan; Leanpolchareanchai, Jiraporn; Saparpakorn, Patchreenart
Molecules, 2009 , vol. 14, # 9 p. 3198 - 3213 Title/Abstract Full Text View citing articles Show Details
Biological material
Naja kaouthia
Assay Description
Effect : fibrinogenolytic activity anti-snake venom metalloproteinase activity Bioassay : venom
Results
complete inhibition concentration 7.05 μmol/l
Citation
Pithayanukul, Pimolpan; Leanpolchareanchai, Jiraporn; Saparpakorn, Patchreenart
Molecules, 2009 , vol. 14, # 9 p. 3198 - 3213 Title/Abstract Full Text View citing articles Show Details
Results
in vitro study on antioxidant effect: inhibition of oxygen consumption and malondialdehyde formation due to lipid peroxidation in rat heart mitochondria
Citation
Hong; Wang; Huang; Hsu
Journal of Pharmacy and Pharmacology, 1995 , vol. 47, # 2 p. 138 - 142 Title/Abstract Full Text View citing articles Show Details
Results
antioxidant activity (inhibitor of bleaching of crocin)
Citation
Cavin, Alexandre; Hostettmann, Kurt; Dyatmyko, Wahjo; Potterat, Olivier
Planta Medica, 1998 , vol. 64, # 5 p. 393 - 396 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of his+ revertants Target : Salmonella typhimurium TA 100 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against captan (CP)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of CP (100 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. dose-dependently reduced the number of CP-induced His+ revertants with 51 percent inhibition of revertant colonies at the highest dose
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of his+ revertants Target : Salmonella typhimurium TA 100 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against nitroso-N-methylurea (MNU)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of MNU (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. dose-dependently reduced the number of MNU-induced His+ revertants with 18 percent inhibition of revertant colonies at the highest dose
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
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Effect
Antimutagenic
Assay Description
Effect : number of his+ revertants Target : Salmonella typhimurium TA 100 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of MNNG (1 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. dose-dependently reduced the number of MNNG-induced His+ revertants with 63 percent inhibition of revertant colonies at the highest dose
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of his+ revertants Target : Salmonella typhimurium TA 97 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against folpet (FP)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of FP (100 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. dose-dependently reduced the number of FP-induced His+ revertants with 64 percent inhibition of revertant colonies at the highest dose
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of His+ revertants Target : Salmonella typhimurium TA 97 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against ICR-170-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. with ICR-170 (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. had a little effect on the number of ICR-191-induced His+ revertants with 11 percent inhibition of revertant colonies at the highest dose
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of His+ revertants Target : Salmonella typhimurium TA 97 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against ICR-191-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. with ICR-191 (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. dose-dependently reduced the number of ICR-191-induced His+ revertants with 32 percent inhibition of revertant colonies at the highest dose
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of His+ revertants Target : Salmonella typhimurium TA 97 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against 4-nitroquinoline-N-oxide (4-NQNO)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. with of 4-NQNO (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
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Results
title comp. dose-dependently reduced the number of 4-NQNO-induced His+ revertants with 43 percent inhibition of revertant colonies at the highest dose
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of His+ revertants Target : Salmonella typhimurium TA 98 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against 9-aminoacridine (9AA)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of 9AA (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. dose-dependently reduced the number of 9AA-induced His+ revertants with 83 percent inhibition of revertant colonies at the highest dose
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of his+ revertants Target : Salmonella typhimurium TA 98 Bioassay : title comp. in phosphate buffer (PB; pH 7.4); estimation of the number of His+ revertants per plate; study of the mechanism of antimutagenic effect of title comp. against 9-aminoacridine (9AA; 10 μg/plate)-induced mutations in vitro; Ames test; title comp., 9AA and cells were incub. for 30 min at 37 deg C in var. combin. (all together; title comp.+9AA for 15 min, then cells; cells + title comp. for 15 min, then 9AA; cells + 9AA for 15 min, then cells); 30-min Ames test
Results
the greatest inhibition of 9AA-induced mutagenesis was obs. when title comp. and bacteria were preincubated together before exposing to 9AA
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of His+ revertants Target : Salmonella typhimurium TA 98 Bioassay : title comp. in phosphate buffer (PB, pH 7.4); S9 mix was prepared from Aroclor 1254-induced Sprague-Dawley rats; estimation of antimutagenic effect of title comp. against aflatoxin B1 (AFB1)induced mutations in vitro; Ames test with metabolic activation; title comp. was incub. in the pres. of AFB1 (1 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. had a little effect on the number of AFB1-induced His+ revertants with 20 percent inhibition of revertant colonies at 100 μg/plate
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Effect
Antimutagenic
Assay Description
Effect : number of His+ revertants Target : Salmonella typhimurium TA 98 Bioassay : title comp. in phosphate buffer (PB, pH 7.4); S9 mix was prepared from Aroclor 1254-induced Sprague-Dawley rats; estimation of antimutagenic effect of title comp. against benzo(a)pyrene (B(a)P)-induced mutations in vitro; Ames test with metabolic activation; title comp. was incub. in the pres. of B(a)P (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. dose-dependently reduced the number of B(a)P-induced His+ revertants with 20 percent inhibition of revertant colonies at 100 μg/plate
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
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Effect
Antimutagenic
Assay Description
Effect : number of His+ revertants Target : Salmonella typhimurium TA 98 Bioassay : title comp. in phosphate buffer (PB, pH 7.4); S9 mix was prepared from Aroclor 1254-induced Sprague-Dawley rats; estimation of antimutagenic effect of title comp. against 2acetylaminofluorene (AAF)-induced mutations in vitro; Ames test with metabolic activation; title comp. was incub. in the pres. of AAF (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants
Results
title comp. had a little effect on the number of AAF-induced His+ revertants with 20 percent inhibition of revertant colonies at 100 μg/plate
Citation
Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun
Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details
Biological material
Staphylococcus aureus
Assay Description
Effect : |drug interaction Bioassay : methicillin resistant S. aureus used; β-lactam antibiotics: oxacillin, cefmetazole, imipenem, benzylpenicillin; other antimicrobial agents: erythromycin, fosfomysin, ofloxacin, streptomycin, tetracycline, vancomycin MICs of β-lactam antibiotics and other antimicrobial agents determined in presence of title comp.
Citation
Shimizu; Shiota; Mizushima; Ito; Hatano; Yoshida; Tsuchiya
Antimicrobial Agents and Chemotherapy, 2001 , vol. 45, # 11 p. 3198 - 3201 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : control: H2O; TNF: tumor necrosis factor; IKK: IκB kinase; GST: glutathione S-transferase cytosolic extract from TNFα-stimulated cells was treated with title comp. for 20 min on ice; IKK activity determined in cytosolic extract by phosphorylation of IκBα-GST fusion protein
Results
title comp. inhibited IKK activity to ca. 70 percent of that in control
Citation
Yang, Fajun; Oz, Helieh S.; Barve, Shirish; De Villiers, Willem J. S.; McClain, Craig J.; Varilek, Gary W.
Molecular Pharmacology, 2001 , vol. 60, # 3 p. 528 - 533 Title/Abstract Full Text View citing articles Show Details
Biological material
Mus musculus Hepa-1c1c7 cell line
Assay Description
Effect : |antagonist Bioassay : AhR: aryl hydrocarbon receptor; TCDD: 2,3,7,8-tetrachlorodibenzo<1,4>dioxin; suppression level: amount of transformed AhRs in percentage to control value TCDD-induced AhR transformation assay; title comp. added to test cells 10 min prior to 0.1 nmol/l TCDD in α-MEM containing 10% FBS under humidified 5% CO2/95% air, incubated at 37 deg C for 2 h; contents of transformed AhRs estimated by ELISA
Citation
Mukai, Rie; Fukuda, Itsuko; Hosokawa, Keizo; Nishiumi, Shin; Kaneko, Atsushi; Ashida, Hitoshi
Bioscience, Biotechnology and Biochemistry, 2005 , vol. 69, # 5 p. 896 - 903 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild + enzyme [Aspergillus nidulans]:Wild
Assay Description
Effect : |enzyme; examination of Bioassay : syringaldazine 0.1 percent (w/v) solution in 95 percent ethanol for detection of peroxidases; reagents added on the medium without fungi (control); results evaluated following the intensity of the color reaction; maximal intensity 5 isolation from soil plates; malt extract agar medium; extracellular phenoloxidases activities detected by direct application of title comp. to the mycelium; noncontaminated soil
Results
extracellular phenoloxidases activities non-contaminated and non-contaminated soil (0)
Citation
Giraud; Guiraud; Kadri; Blake; Steiman
Water Research, 2001 , vol. 35, # 17 p. 4126 - 4136 Title/Abstract Full Text View citing articles Show Details
Target
enzyme [Hypocrea lixii]:Wild
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Assay Description
Effect : |enzyme; examination of Bioassay : syringaldazine 0.1 percent (w/v) solution in 95 percent ethanol for detection of peroxidases; control from Collection Mycology Pharmacy Grenoble; results evaluated following the intensity of the color reaction; maximal intensity 5 isolation from soil plates; malt extract agar medium; extracellular phenoloxidases activities detected by direct application of title comp. to the mycelium; noncontaminated soil
Results
extracellular phenoloxidases activities non-contaminated soil (0)
Citation
Giraud; Guiraud; Kadri; Blake; Steiman
Water Research, 2001 , vol. 35, # 17 p. 4126 - 4136 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Results
title comp. resulted to a dose dependent increase of FRAP in plasma; FRAP levels in title comp.-exposed plasma lower than ascorbic acid at all conc.; fig.
Citation
DeGraft-Johnson, Jeffrey; Kolodziejczyk, Krzysztof; Krol, MacIej; Nowak, Piotr; Krol, Boguslaw; Nowak, Dariusz
Basic and Clinical Pharmacology and Toxicology, 2007 , vol. 100, # 5 p. 345 - 352 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
human HL-60 cell line
Assay Description
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Bioassay : DCF-DA: 2',7'-dichlorofluorescein diacetate in vitro; cells differentiated for 5 d in DMSO solution; scavenging effect of title comp. on exogeneous H2O2 assayed; 1E6 cells/mL; Hanks' balanced salt solution; incubation 90 min; 37 deg C; residual H2O2 determined by DCF-DA method in flow cytometer
Results
conc.-response profile; title comp. exhibited weak scavenging activity in a dose-dependent manner
Citation
Lin, Jen-Kun; Chen, Ping-Chung; Ho, Chi-Tang; Lin-Shiau, Shoei-Yn
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 7 p. 2736 - 2743 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
human HL-60 cell line
Assay Description
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Target : human plasma Bioassay : TPTZ: 2,4,6-tripirydyl-s-triazyne; control: plasma incub. in water with or without DMSO; FRAP: ferric-reducing ability power; positive controls: ascorbic acid or Trolox(R) plasma incub. with title comp. in the presence of FeCl3 and TPTZ for 10 min at 37 deg C; pH 3.6; increase in absorbance at 593 nm monitored
Bioassay : Hanks' balanced salt solution; superoxide level quantified for 2 h by chemiluminescence assay; PMA: phorbol-12-myristate-13-acetate in vitro; cells differentiated for 5 d in DMSO solution; inhibition of PMA (100 ng/mL)-stimulated superoxide production assayed; 2.5E5 cells; cells preincubated with title comp. and 200 μM lucigenin for 5 min, then stimulated with PMA
Results
conc.-response profile; title comp. potentiated PMA-stimulated superoxide production
Citation
Lin, Jen-Kun; Chen, Ping-Chung; Ho, Chi-Tang; Lin-Shiau, Shoei-Yn
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 7 p. 2736 - 2743 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
human HL-60 cell line
Assay Description
Results
Bioassay : 37 deg C; incubation time 90 min; H2O2 production determined by measuring HRP-mediated scopoletin oxidation using fluorescence assay; PMA: phorbol-12-myristate-13-acetate; HRP: horse radish peroxidase in vitro; cells differentiated for 5 d in DMSO solution; inhibition of PMA (100 ng/mL)-stimulated H2O2 production assayed; 2.5E5 cells; Hanks' balanced salt solution; cells preincubated with title comp., scopoletin, NaN3 and purogallin (1U/mL) for 5 min conc.-response profile; title comp. inhibited H2O2 production in a dose-dependent manner
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Citation
Lin, Jen-Kun; Chen, Ping-Chung; Ho, Chi-Tang; Lin-Shiau, Shoei-Yn
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 7 p. 2736 - 2743 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
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Target : human erythrocyte membrane ghosts Bioassay : spectrophotometry; control: contained no title comp.; TBA: thiobarbituric acid in vitro; antioxidant activity against Fe2+-induced lipid oxidation assayed; human blood drawn from healthy graduate students; 5 μmol/l FeSO4; PBS, pH 7.2; 37 deg C; lipid oxidation measured by TBA assay at 0, 36 and 72 h and recorded as TBA number
Results
title comp. significantly delayed Fe2+-induced lipid oxidation when compared with control, TBA number/control/dose(μmol/l) after 72 h incubation: 0.366-0.374-0.381/0.531-0.520-0.519/5 and 0.2740.273-0.281-0.271/0.531-0.520-0.519-0.535/10,
Citation
Liao, Kuei-Long; Yin, Mei-Chin
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 6 p. 2266 - 2270 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Biological material
human thrombocyte
Assay Description
Effect : |enzyme; induction of Bioassay : incubated for 20 min; liquid scintillation spectrometry effect on M-form phenolsulfotransferase (PST-M) activity evaluated; platelets obtained from blood collected from healthy adult volunteers; 10 μmol/l dopamine; 6.7 μmol/l <35S>-3'-phosphoadenosine-5'-phosphosulfate; assay buffer, pH 7.0; 37 deg C
Results
at 2.5/5.0/7.5 μmol/l title comp. promoted PST-M activity by 5/9/10 percent
Citation
Yeh, Chi-Tai; Shih, Ping-Hsiao; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 13 p. 4139 - 4143 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Biological material
human thrombocyte
Assay Description
Effect : |enzyme; induction of Bioassay : incubated for 20 min; liquid scintillation spectrometry effect on P-form phenolsulfotransferase (PST-P) activity evaluated; platelets obtained from blood collected from healthy adult volunteers; 3 μmol/l p-nitrophenol; 6.7 μmol/l <35S>-3'-phosphoadenosine-5'-phosphosulfate; assay buffer, pH 7.0; 37 deg C
Results
at 2.5/5.0/7.5 μmol/l title comp. promoted PST-P activity by 12/26/28 percent
Citation
Yeh, Chi-Tai; Shih, Ping-Hsiao; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 13 p. 4139 - 4143 Title/Abstract Full Text View citing articles Show Details
Results
inhibitor (IC 50 (μM)) of wheat embryo Ca2+-dependent protein kinase (MLCP-substrate) (not active); or (III-S histones - substrate) (not active)
Citation
Polya; Wang Bing Hui; Foo
Phytochemistry, 1995 , vol. 38, # 2 p. 307 - 314 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : nalbuphine metabolism; inhibition of Target : liver microsome of Sprague-Dawley rat Bioassay : Experiment 1. In Vitro Experiment of UGT2B Inhibitor Material and Method: 1. The Preparation of UGT2B Inhibitor In the following experiment, 27 different kinds of CHEs were used as UGT2B inhibitor in this invention. These CHEs are pure compounds available commercially, and were purchased from Sigma
Results
title compound showed 8.051 - 15.842 % inhibitory effect at a concentration of 8.5 - 850 μmol/l
Citation
National Defense Medical Center; National Defense University
Patent: US2006/40875 A1, 2006 ;
Title/Abstract Full Text Show Details
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Results
in vitro no inhibition of insulin-stimulated lipogenesis in male Wistar rats adipose tissue at conc. up to 1 mM
Citation
Ong; Khoo; Das
Experientia, 1995 , vol. 51, # 6 p. 577 - 584 Title/Abstract Full Text View citing articles Show Details
Results
antioxidant acitivity by the rabbit erythrocyte membrane ghost method, IC50 = 106 μM
Citation
Okamura, Hideo; Mimura, Akio; Yakou, Yasuko; Niwano, Mitsuru; Takahara, Yoshimasa
Phytochemistry (Elsevier), 1993 , vol. 33, # 3 p. 557 - 562 Title/Abstract Full Text View citing articles Show Details
Results
Growth inhibitory activity against larvae of Heliothis virescens; EC50: 7.40 mmol/kg diet
Citation
Klocke, James A.; Wagenen, Brad Van; Balandrin, Manuel F.
Phytochemistry (Elsevier), 1986 , vol. 25, # l p. 85 - 92 Title/Abstract Full Text Show Details
Results
inactivation of reed β-glucan synthase
Citation
Mason, Theresa L.; Wasserman. Bruce P.
Phytochemistry (Elsevier), 1987 , vol. 26, # 8 p. 2197 - 2202 Title/Abstract Full Text View citing articles Show Details
Results
no inhibiting activity against alpha-acid oxidase enzyme
Citation
Williams, Elizabeth A.; Menary, Robert C.
Phytochemistry (Elsevier), 1988 , vol. 27, # 1 p. 35 - 40 Title/Abstract Full Text View citing articles Show Details
Results
inhibitory activity (percent) against phenylalanine ammonia-lyase derived from: sweet potato 72, pea 60, yeast 3; inhibition constant 8.8E-5 M (sweet potato)
Citation
Sato, Toshitsugu; Kiuchi, Fumiyuki; Sankawa, Ushio
Phytochemistry (Elsevier), 1982 , vol. 21, # 4 p. 845 - 850 Title/Abstract Full Text View citing articles Show Details
Results
inhibitory effect on glucan synthesis by glucosyltransferase from Streptococcus mutans
Citation
Kakiuchi; Hattori; Nishizawa; Yamagishi; Okuda; Namba
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 720 - 725 Title/Abstract Full Text View citing articles Show Details
Results
no shows the blood urea nitrogen (BUN)-decreasing activity in rat serum
Citation
Shibutani; Nagasawa; Oura; Nonaka; Nishioka
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 3 p. 874 - 878 Title/Abstract Full Text View citing articles Show Details
Results
inhibitory effect on TPA-induced inflammation in mice
Citation
Yasukawa; Takido; Takeuchi; Nakagawa
Chemical and pharmaceutical bulletin, 1989 , vol. 37, # 4 p. 1071 - 1073 Title/Abstract Full Text View citing articles Show Details
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Results
inhibition of mutagenicity of 3-amino-1-methyl-5H-pyrido<4,3-b>indole, using Salmonella typhimurium TA98 and TA100
Citation
Okuda; Mori; Hayatsu
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 9 p. 3755 - 3758 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : endothelium-dependent relaxation; effect on Target : aortic ring of New Zealand White rabbit Bioassay : Effect of different procyanidins on endothelium-dependent relaxation was tested in an ex vivo experiment performed as previously described by Karim et al., J. Nutrl Suppl., 130 (8S): 2105S2108S (2000), the relevant portions of which are hereby incorporated herein by reference. The advantage of using
Results
HUVEC-mediated MTT reduction following 5 subsequent 24 h treatment with test compound at 10 μM; % MTT reduction near 50
Citation
Mars, Incroporated
Patent: US2005/277600 A1, 2005 ; Title/Abstract Full Text Show Details
Assay Description
Effect : nitric oxide production; effect on Target : human umbilical vein endothelial cell (HUVEC) of human Bioassay : Test compounds were evaluated with respect to their potential to acutely (24 hour) and chronically (5 doses given in 24 hour intervals) modulate NO production. Positive controls (acetylcholine and/or histamine) and negative control L-NNMA (NO synthase inhibitor) were included in all experiments. Cell
Results
Nitric oxide production induced folowing 24 h treatment with test compound at 20 μM - concentration near 1 μM
Citation
Mars, Incroporated
Patent: US2005/277600 A1, 2005 ; Title/Abstract Full Text Show Details
Effect
Chemoprotective
Assay Description
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Results
protective activity against the cell damage induced by superoxide anion radicals; little effect on survival at 50 μM but 43.5-79.7 percent survival at 100-1000 μM (control: 36.9 percent)
Citation
Masaki; Atsumi; Sakurai
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 1 p. 59 - 63 Title/Abstract Full Text View citing articles Show Details
Effect
Chemoprotective
Assay Description
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Target : dermal fibroblasts from ICR mice Bioassay : 37 deg C; ESR spin-trapping after 1 d of cultivation, cells were exposed to 1.5 mM hypoxanthine, 500 unit/ml catalase, 40 munit/ml xanthine oxidase dissolved in Hank's buffer HBS in the presence of test agent
Target : dermal fibroblasts from ICR mice Bioassay : 37 deg C fibroblasts treated with test agent for 24 h, after washing to remove it, fibroblasts were placed in contact with superoxide anions generated by hypoxanthine-xanthine oxidase HPXXOD catalase system
Results
survival of the control and pre-treated (200 μM) fibroblasts were 17.7 percent and 25.4 percent
Citation
Masaki; Atsumi; Sakurai
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 1 p. 59 - 63 Title/Abstract Full Text View citing articles Show Details
Effect
Phytotoxic
Biological material
wheat
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Results
100 percent inhibition of root growth of germinated wheat
Citation
Shukla; Srivastava, Anil; Kumar, Sushil
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 6 p. 705 - 708 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
K-562 cell line
Assay Description
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Results
IC50: 2.22
Citation
Hou; Peng; Liu; Lin; Sun
Planta Medica, 2000 , vol. 66, # 7 p. 624 - 626 Title/Abstract Full Text View citing articles Show Details
Effect
Antibiotic
Assay Description
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Target : human HL cells Bioassay : FITC: fluorescein isothiocyanate-conjugated chlamydial genus-specific antibody; C. pneumoniae: Chlamydia pneumoniae isolate Kajaani 7 (K7), 1E3 inclusion-forming units/well cell monolayers infected with C. pneumoniae; after 60-min centrifugation, title comp. added for 72 h at 37 deg C, then cells washed and fixed; chlamydial inclusions stained with FITC and examined under fluorescence microscope
Results
50 μmol/l title comp. caused ca. 27 percent inhibition of inclusion forming
Citation
Alvesalo; Vuorela; Tammela; Leinonen; Saikku
Biochemical Pharmacology, 2006 , vol. 71, # 6 p. 735 - 741 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Bioassay : 4E4 cells/ml at a log phase incubated with title comp. in 96-well plates at 37 deg C for 48 h; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide added, 4 h; SDS-iBuOH-HCl added; after 12 h at r.t. optical density at 570 nm and 630 nm measured
Target : human HL cells Bioassay : LDH: lactate dehydrogenase LDH levels determined after 2 and 72 h exposure to title comp. by using commercial LDH test kit; dead cells counted after 72 h incubation with title comp. via Trypan blue staining
Citation
Alvesalo; Vuorela; Tammela; Leinonen; Saikku
Biochemical Pharmacology, 2006 , vol. 71, # 6 p. 735 - 741 Title/Abstract Full Text View citing articles Show Details
Results
antioxidant activity
Citation
Takahashi, Hironobu; Iuchi, Miho; Fujita, Yoshimi; Minami, Hiroyuki; Fukuyama, Yoshiyasu
Phytochemistry, 1999 , vol. 51, # 4 p. 543 - 550 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |antagonist Target : Sprague-Dawley rat liver cytosol Bioassay : effect on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced aryl hydrocarbon receptor transformation evaluated by electrophoretic mobility shift assay; assay buffer, pH 7.4; 20 deg C; incubated for 10 min; 0.1 nmol/l TCDD added for further 2 h
Citation
Fukuda, Itsuko; Sakane, Iwao; Yabushita, Yoshiyuki; Kodoi, Rie; Nishiumi, Shin; Kakuda, Takami; Sawamura, Shin-Ichi; Kanazawa, Kazuki; Ashida, Hitoshi
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 9 p. 2499 - 2506 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
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Assay Description
Effect : |enzyme; inhib. of Bioassay : chitin synthase III prepared from recombinant Saccharomyces cerevisiae ECY38-38A (pWJC6) membrane suspension incub. in Tris-HCl buffer pH 7.5 with Mg(OAc)2, UDP-<U-14C>-Nacetylglucosamine, trypsin, title comp. at 30 deg C, 15 min; stopped by soybean trypsin inhibitor; N-acetylglucosamine added, 90 min, 30 deg C; amount of chitin determined
Citation
Hwang; Ahn; Lee; Kim; Bok
Planta Medica, 2001 , vol. 67, # 6 p. 501 - 504 Title/Abstract Full Text View citing articles Show Details
Effect
Vasoconstrictor
Assay Description
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Results
title comp. inhibited ACh-induced relaxation; effect did not depend on cyclooxygenase activity (diagram)
Citation
Sanae, Fujiko; Miyaichi, Yukinori; Hayashi, Hisao
Planta Medica, 2002 , vol. 68, # 8 p. 690 - 693 Title/Abstract Full Text View citing articles Show Details
Effect
Vasoconstrictor
Assay Description
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Target : Wistar rat aortic strip Bioassay : control: without title comp.; further investigation on mechanism of action using indomethacin (IM), BQ610, L-NAME and L-arginine; L-NAME: NG-nitro-L-arginine methyl ester thoracic aorta strips with or without endothelium were mounted in organ bath at 37 deg C; resting tension was adjusted to 1 g; strips precontracted with phenylephrine and title comp. was added cumulatively; isometric tension was assessed
Results
title comp. in conc.-dependent manner stimulated further contraction of phenylephrine-precontructed strips with intact endothelium; effect was inhibited by NO synthesis activation and did not depend on endothelin receptors and cyclooxygenase
Citation
Sanae, Fujiko; Miyaichi, Yukinori; Hayashi, Hisao
Planta Medica, 2002 , vol. 68, # 8 p. 690 - 693 Title/Abstract Full Text View citing articles Show Details
Effect
Vasoconstrictor
Assay Description
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Target : Wistar rat aortic strip Bioassay : control: without title comp.; ACh: acetylcholine; further investigation of mechanism of action using indomethacin intact thoracic aorta strips were mounted in organ bath at 37 deg C; strips incubated with title comp. for 15 min, contracted by phenylephrine; ACh-induced relaxation was assessed
Target : Wistar rat aortic strip Bioassay : control: without title comp. thoracic aorta strips without endothelium were mounted in organ bath at 37 deg C; strips incubated with title comp. for 15 min and contracted by phenylephrine; sodium nitroprusside-induced relaxation was assessed
Results
title comp. inhibited sodium nitroprusside-induced relaxation (diagram)
Citation
Sanae, Fujiko; Miyaichi, Yukinori; Hayashi, Hisao
Planta Medica, 2002 , vol. 68, # 8 p. 690 - 693 Title/Abstract Full Text View citing articles Show Details
Effect
Vasoconstrictor
Assay Description
Target : Wistar rat aortic strip Bioassay : control: without title comp. thoracic aorta strips without endothelium were mounted in organ bath at 37 deg C; strips incubated with title comp. for 15 min; contracted by phenylephrine and prostacyclin-induced relaxation was assessed
Results
title comp. inhibited prostacyclin-induced relaxation (diagram)
Citation
Sanae, Fujiko; Miyaichi, Yukinori; Hayashi, Hisao
Planta Medica, 2002 , vol. 68, # 8 p. 690 - 693 Title/Abstract Full Text View citing articles Show Details
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Target
histidine decarboxylase [human]:Wild
Assay Description
Effect : enzyme activity; inhibition of Bioassay : 3.2 mM L-histidine; assay buffer, pH 6.8; 37 deg C; incubated with title comp. for 1 h; formation of histamine measured
Results
title comp. inhibited enzyme activity to ca. 91% of control; fig.
Citation
Nitta, Yoko; Kikuzaki, Hiroe; Ueno, Hiroshi
Journal of agricultural and food chemistry, 2007 , vol. 55, # 2 p. 299 - 304 Title/Abstract Full Text Show Details
Assay Description
Effect : enzyme activity; inhibition of
Citation
Ha, Tae Joung; Kubo, Isao
Journal of agricultural and food chemistry, 2007 , vol. 55, # 2 p. 446 - 451 Title/Abstract Full Text Show Details
Assay Description
Effect : protein cleavage; induction of Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : PARP: poly (ADP-ribose) polymerase cells incubated with title comp. for 6 h; level of procaspase 3 and active caspase 3 (32 and 17 kDa), full and fragmented forms of PARP protein (116 and 85 kDa) measured by Western blotting
Results
title comp. dose-depend. induced cleavage of procaspase 3 into active form and fragmentation of PARP protein; fig.
Citation
Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng
Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : protein level; decrease of Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : cells incubated with title comp. for 2-6 h; level of Bcl-2 protein measured by Western blotting
Results
title comp. dose- and time-depend. decreased Bcl-2 protein amount; fig.
Citation
Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng
Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : protein level; increase of Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : cells incubated with title comp. for 2-6 h; level of cytosolic cytochrome c (cyt c) and Bax protein levels measured by Western blotting
Results
title comp. dose- and time-depend. increased cytosolic cyt c level and Bax protein amount; fig.
Citation
Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng
Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : reactive oxygen species production; increase of Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : further invest. with vitamin C, vitamin E and catalase cells incubated with title comp. for 0.5-2 h; intracellular ROS production detected by flow cytometry using 2',7'-dihydrofluoresceindiacetate; propidium iodide staining
Results
title comp. time-depend. increased ROS production; effect decreased by catalase; fig.
Citation
Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng
Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details
Biological material
human lymphocyte
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Assay Description
Effect : |growth inhibition Bioassay : cells incubated with title comp. for 12 h; cell number counted with hemocytometer
Citation
Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng
Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Results
title comp. dose- and time-depend. inhibited cell growth by ca. 2.2-fold at highest conc. after 6 h of incubation (ca. 2-fold inhibition observed for taxol); cell shrinkage observed; effect decreased by catalase; fig.
Citation
Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng
Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details
Effect
Hemolytic
Biological material
human erythrocyte
Assay Description
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Bioassay : cells incubated with title comp. for 15 h; hemolysis analyzed
Citation
Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng
Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |biotransformation Target : recombinant PDC of Lactobacillus plantarum CECT 748T
Bioassay : incubation mixture lacking enzyme used as control; PDC: p-coumaric acid decarboxylase ATCC 14917, DSMZ 20174; incubated with title comp. in phosphate buffer (pH 6.5) at 30 deg C for 4 h; formation of degradation products analyzed by HPLC-DAD
Citation
Rodriguez, Hector; Landete, Jose Maria; Curiel, Jose Antonio; De Las Rivas, Blanca; Mancheno, Jose Miguel; Munoz, Rosario
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 9 p. 3068 - 3072 Title/Abstract Full Text View citing articles Show Details
Effect
Antineoplastic
Biological material
A-549
Assay Description
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Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : 0.5 μg/ml taxol used for reference; further invest. with vitamin C, vitamin E and catalase cells incubated with title comp. for 2-6 h; cell growth and viability assessed by trypan blue exclusion assay; cell morphology analyzed using phase contrast microscopy
PDP was concentration-dependent
Results
inhibition ratio 15.92 - 74.6 percent
Citation
Zhao, Yan-Li; He, Qiu-Xia; Li, Yang; Wang, Si-Feng; Liu, Ke-Chun; Yang, Yong-Ping; Li, Xiao-Li
Molecules, 2010 , vol. 15, # 4 p. 2178 - 2186 Title/Abstract Full Text View citing articles Show Details
Effect
Antiproliferative
Assay Description
Results
Target : 3T3-L1 preadipocytes BCRC 60159 Bioassay : DMEM with 10 percent FBS; humidified 5 percent CO2; 37 deg C; incubated for 24, 48, and 72 h; cell cycle analysis by flow cytometry title comp. did not affect cell cycle profile of cells; however, it markedly time- and conc.-dependently increased accumulation of the sub-G1 phase (apoptotic cells)
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Citation
Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Results
title comp. induced LDH leakage in time- and conc.-dependent manner
Citation
Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : positive control: pepstatin A, IC50 = 0.016 μmol/l in vitro; incubation time: 1 h; 37 deg C; fluorescence at 360ex/530em
Citation
Li; Jacob; Pasco; ElSohly; Nimrod; Walker; Clark
Journal of Natural Products, 2001 , vol. 64, # 10 p. 1282 - 1285 Title/Abstract Full Text View citing articles Show Details
Results
no larvicidal activity, no bursting activity in the presence of decanoic acid against larvea of Toxacara canis
Citation
Kiuchi; Tsuda; Kondo; Yoshimura; Nishioka; Nonaka
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 5 p. 1796 - 1802 Title/Abstract Full Text View citing articles Show Details
Effect
Antiprotozoal
Biological material
Trichomonas vaginalis
Assay Description
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Target : 3T3-L1 preadipocytes BCRC 60159 Bioassay : DMEM with 10 percent FBS; humidified 5 percent CO2; 37 deg C; incubated for 24-72 h; LDH leakage into culture medium analyzed
Bioassay : Example 1 Effect of 1.1 Percent Gallic Acid on the Growth of Trichomonas vaginalis A sterile LYI-S-2 medium was prepared according to the manufacturer's instructions, and the pH of this medium was adjusted to pH 6.0 using 1 N HCl. Gallic acid monohydrate (SIGMA-398225 from Signa Aldrich, USA) was dissolved
Results
title comp. showed activity against Trichomonas vaginalis
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details
Effect
Antiprotozoal
Biological material
Trichomonas vaginalis
Assay Description
Bioassay : Example 2 Effect of Various Concentrations of Gallic Acid on the Growth of Trichomonas vaginalis Essentially the same procedure was performed as described in Example 1, but this time differing concentrations of gallic acid were tested on samples of Trichomonas vaginalis. The gallic acid concentrations
Results
title comp. showed activity against Trichomonas vaginalis
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details
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Effect
Antiprotozoal
Biological material
Gardnerella vaginalis
Assay Description
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Results
title comp. showed activity against Gardnerella vaginalis
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details
Effect
Bacteriostatic
Biological material
Lactobacillus acidophilus
Assay Description
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Bioassay : Example 3 Effect of Gallic Acid on the Growth of Candida albicans and Lactobacillus acidophilus-Zone-of-Inhibition Test A microorganism culture of 105 cfu (colony forming units)/milliliter in a 1&times; phosphate buffered saline (PBS) solution (diluted from 10&times; PBS LIQUID CONCENTRATE
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details
Effect
Bacteriostatic
Biological material
Lactobacillus acidophilus
Assay Description
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Bioassay : Example 5 Effect of Gallic Acid on the Growth of Gardnerella vaginalis-Inhibition Test in Solution by Plate Count A test compound of Gardnerella vaginalis was prepared in culture media to form a suspension. Control and gallic acid solutions (0.9 milliliters; 7.5 milligram gallic acid/milliliter) were
Bioassay : Example 4 Effect of Gallic Acid on the Growth of Candida albicans and Lactobacillus acidophilus-Inhibition Tests in Solution by Measuring Optical Density Test compounds of Candida albicans and Lactobacillus acidophilus were dissolved in culture media to form a suspension. Control and gallic acid solutions
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details
Biological material
Candida albicans
Assay Description
Effect : fungostatic Bioassay : Example 3 Effect of Gallic Acid on the Growth of Candida albicans and Lactobacillus acidophilus-Zone-of-Inhibition Test A microorganism culture of 105 cfu (colony forming units)/milliliter in a 1&times; phosphate buffered saline (PBS) solution (diluted from 10&times; PBS LIQUID CONCENTRATE
Results
title comp. showed activity against Candida albicans
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details
Biological material
Candida albicans
Assay Description
Effect : fungostatic Bioassay : Example 4 Effect of Gallic Acid on the Growth of Candida albicans and Lactobacillus acidophilus-Inhibition Tests in Solution by Measuring Optical Density Test compounds of Candida albicans and Lactobacillus acidophilus were dissolved in culture media to form a suspension. Control and gallic acid solutions
Results
title comp. showed activity against Candida albicans
Citation
Kimberly-Clark Worldwide, Inc.
Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details
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Effect
Antiproliferative
Biological material
human HCT 116 cell line
Assay Description
Effect : antiproliferative Antiproliferative Activities of Isolated Phenolics from Maple Syrup on Colon Cells The antiproliferative activities of phenolics previously isolated from maple syrup extracts are evaluated after both 48 and 72 h of treatment (Table 14). All of the pure compounds inhibited proliferation of the HCT-1
Results
IC50 (μmol/l) = 64.9, 42.1 after 48, 72 h treatment, respectively
Citation
SEERAM, Navindra, P.; LI, Liya; B&Eacute; LAND, Genevi&egrave; ve; BARBEAU, Julie
Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details
Assay Description
Effect : tumor cell migration; inhibition of Target : murine colon 26-L5 adenocarcinoma cell line Bioassay : vehicle control; cells stained with 0.5 percent crystal violet for 30 min 2E5 cells incub. with var. conc. of title comp. in RPMI-1640 medium with 0.1 percent bovine serum albumin for 30 min on ice, then added to upper compartment of Transwell chamber, incub. 3 h at 37 deg C; cells stained, migrated cells extracted, absorbance det.
Citation
Ogasawara, Masaru; Matsubara, Toshiyuki; Suzuki, Hideyo
Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 6 p. 720 - 723 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
Rattus norvegicus liver cell
Assay Description
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Bioassay : incubation: Krebs-Henseleit buffer (pH 7.4); 12.5 mmol/l HEPES; 0.1 percent albumin; 37 deg C male Fisher 344 rats (260-290 g); hepatocytes isolated by collagenase perfusion of the liver; cell viability by trypan blue exclusion
Results
no significant effect on cell death: 20.3 percent (control) vs. 25.5 percent (title comp.);
Citation
Nakagawa, Yoshio; Nakajima, Kazuo; Tayama, Sumiko; Moldeus, Peter
Molecular Pharmacology, 1995 , vol. 47, # 5 p. 1021 - 1027 Title/Abstract Full Text View citing articles Show Details
Results
1,1-diphenyl-2-picrylhydrazyl free radical scavenging activty, IC50=5.0 μg/ml; inhibition of TPA-induced free radical formation in cultured HL-60 cells, IC50=1.5 μg/ml
Citation
Chung, Ha Sook; Chang, Leng Chee; Lee, Sang Kook; Shamon, Lisa A.; Van Breemen, Richard B.; Mehta, Rajendra G.; Farnsworth, Norman R.; Pezzuto, John M.; Kinghorn, A. Douglas
Journal of Agricultural and Food Chemistry, 1999 , vol. 47, # 1 p. 36 - 41 Title/Abstract Full Text View citing articles Show Details
Results
active oxygen scavenging activity in soybean seed
Citation
Yoshiki, Yumiko; Okubo, Kazuyoshi
Bioscience, Biotechnology, and Biochemistry, 1995 , vol. 59, # 8 p. 1556 - 1557 Title/Abstract Full Text Show Details
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : PAPS: 3'-phosphoadenosine 5'-phosphosulfate; P-ST: phenol sulfotransferase in vitro; effect on P-ST activity assayed; phosphate buffer, pH 7.4; 1 μmol/l <35S>PAPS - sulfate donor; 50 μmol/l 2-naphthol - sulfate acceptor; incub. with title comp. for 15 min at 37 deg C; enzyme activity measured by liquid scintillation counting
Citation
Tamura, Hiro'omi; Miyawaki, Atsushi; Yoneshima, Hiroyuki; Mikoshiba, Katsuhiko; Matsui, Michio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 3 p. 234 - 239 Title/Abstract Full Text View citing articles Show Details
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Biological material
Rattus norvegicus
Assay Description
Effect : |biotransformation Bioassay : in vitro; metabolism of title comp. assayed; metabolites detected by HPLC
Results
no metabolites detected
Citation
Zong, Li; Inoue, Makoto; Nose, Mitsuhiko; Kojima, Keisuke; Sakaguchi, Nahoko; Isuzugawa, Kazuto; Takeda, Tadahiro; Ogihara, Yukio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 3 p. 326 - 329 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Assay Description
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Results
title comp. produced internucleosomal DNA cleavage
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Target : Balb-c mouse thymocytes Bioassay : thymocytes, obtained from crushed mouse thymi, suspended in RPMI-1640 medium (containing HEPES 20mM/l) enriched with fetal calf serum title comp. added to suspension of 4E6 cells in RPMI-1640 medium; after 1 h hydrocortisone hemisuccinate added; incub., 37 deg C, 18-20 h; cells colored with trypan blue and number of living and dead cells counted
Results
significant stimulation of immunological activity at highest dose; percent of thymocyte viability/dose (μg/ml): 98/0.1, 92/1.0, 100/10, 116/50; control: thymus factor X preparation (from calf thymus): 117/50
Citation
Drozd, Janina; Anuszewska, Elzbieta
Acta Poloniae Pharmaceutica - Drug Research, 2003 , vol. 60, # 3 p. 197 - 200 Title/Abstract Full Text View citing articles Show Details
Effect
Antitrypanosomal
Assay Description
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Target : human promyelocytic leukemia HL-60RG cells Bioassay : in vitro; effect on DNA damage assayed; 6E6 cells/ml; incub. with title comp. for 48 h in 5 percent CO2; DNA isolated and subjected to agarose gel electrophoresis
Target : Trypanosoma brucei brucei GUTat 3.1 clone Bioassay : further investigation on mechanism of action using antioxidants superoxide dismutase (SOD) and catalase trypanosome suspension in culture medium (5E5/ml) incubated with title comp. at 37 deg C in 5 percent CO2 for 24 h; number of surviving trypanosomes determined by counting in a haemocytometer
Results
title comp. in concentration-dependent manner induced trypanocidal activity with complete inhibition at 125 μmol/l and higher; reactive oxygen intermediates (superoxide anion and hydrogen peroxide) may mediate title comp. activity
Citation
Nose, Mitsuhiko; Koide, Tatsuo; Morikawa, Kyoko; Inoue, Makoto; Ogihara, Yukio; Yabu, Yoshisada; Ohta, Nobuo
Biological and Pharmaceutical Bulletin, 1998 , vol. 21, # 6 p. 583 - 587 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Assay Description
Target : plasmid pBR 322 DNA Bioassay : further investigation on mechanism of action using superoxide dismutase (SOD) and catalase supercoiled DNA incubated with title comp. at 37 deg C for 1 h with or without FeSO4 or H2O2 in sodium phosphate buffer (pH 7.4); agarose gel electrophoresis; strand breaking was assessed
Results
title comp. in concentration-dependent manner activated DNA breaks (figure)
Citation
Nose, Mitsuhiko; Koide, Tatsuo; Morikawa, Kyoko; Inoue, Makoto; Ogihara, Yukio; Yabu, Yoshisada; Ohta, Nobuo
Biological and Pharmaceutical Bulletin, 1998 , vol. 21, # 6 p. 583 - 587 Title/Abstract Full Text View citing articles Show Details
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Target
enzyme:Wild
Assay Description
Effect : enzyme activity; effect on Bioassay : control: acarbose (IC50: 210 μg/ml), 1-deoxynojirimycin (IC50: 27.1 μg/ml) sucrase activity det. using sucrose as substrate; liberated glucose det. by glucoseoxidase method
Citation
Shinde, Jayantrao; Taldone, Tony; Barletta, Michael; Kunaparaju, Naveen; Hu, Bo; Kumar, Sunil; Placido, Jessica; Zito, S. William
Carbohydrate Research, 2008 , vol. 343, # 7 p. 1278 - 1281 Title/Abstract Full Text View citing articles Show Details
Target
alpha-glucosidase [Geobacillus stearothermophilus]:Wild
Assay Description
Effect : enzyme activity; effect on Bioassay : control: acarbose, 1-deoxynojirimycin (IC50: 0.175 μg/ml) enzyme treated with title comp. for 5 min at 37 deg C, pH 6.8, then incub. with p-nitrophenyl α-D-glucuronide for 20 min at 37 deg C; released p-nitrophenol det. spectrophotometrically at 405 nm
Citation
Shinde, Jayantrao; Taldone, Tony; Barletta, Michael; Kunaparaju, Naveen; Hu, Bo; Kumar, Sunil; Placido, Jessica; Zito, S. William
Carbohydrate Research, 2008 , vol. 343, # 7 p. 1278 - 1281 Title/Abstract Full Text View citing articles Show Details
Target
alpha-glucosidase [Saccharomyces cerevisiae]:Wild
Assay Description
Effect : enzyme activity; effect on Bioassay : control: acarbose, 1-deoxynojirimycin (IC50: 83.4 μg/ml) enzyme treated with title comp. for 5 min at 37 deg C, pH 6.8, then incub. with p-nitrophenyl α-D-glucuronide for 20 min at 37 deg C; released p-nitrophenol det. spectrophotometrically at 405 nm
Citation
Shinde, Jayantrao; Taldone, Tony; Barletta, Michael; Kunaparaju, Naveen; Hu, Bo; Kumar, Sunil; Placido, Jessica; Zito, S. William
Carbohydrate Research, 2008 , vol. 343, # 7 p. 1278 - 1281 Title/Abstract Full Text View citing articles Show Details
Effect
Genotoxic
Biological material
VERO
Assay Description
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Results
score: 70-78, control: 10, reference: 153-198
Citation
Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira
Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details
Effect
Antiproliferative
Assay Description
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Bioassay : control: MEM (minimum essential medium); reference: H2O2, 100 and 200 μmol/l confluent cells incubated with 2 non-cytotoxic but antiherpetic conc.-s of title comp. at 37 deg C in humidified 5 percent CO2 atmosphere for 90 min in MEM; cellular DNA damage assessed by the Comet assay, scores: 0 (all undamaged) to 200 (all max. damaged)
Target : Spodoptera frugiperda larvae Bioassay : reference: commercial extract of neem larval weigth lost control: 100 antifeedant activity bioassay
Results
larval weight lost: 23, reference: 2.5
Citation
Urrea-Bulla; Suarez M; Moreno-Murillo
Fitoterapia, 2004 , vol. 75, # 3-4 p. 392 - 394 Title/Abstract Full Text View citing articles Show Details
Biological material
RAW 264.7 cell line
Assay Description
Effect : gene expression; effect on Bioassay : gene expression of inducible nitric oxide synthase (iNOS), cytokines interleukin (IL)-1, IL-10, IL-12, IL-18, TNF-α and interferon (IFN)-γ was investigated by reverse-transcription polymerase chain reaction
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Results
low and transient levels of TNFα and IL-10 were induced
Citation
Radtke, Oliver A.; Kiderlen, Albrecht F.; Kayser, Oliver; Kolodziej, Herbert
Planta Medica, 2004 , vol. 70, # 10 p. 924 - 928 Title/Abstract Full Text View citing articles Show Details
Biological material
RAW 264.7 cell line
Assay Description
Effect : gene expression; effect on Bioassay : Leishmania major-infected cells; gene expression of inducible nitric oxide synthase (iNOS), cytokines interleukin (IL)-1, IL-10, IL-12, IL-18, TNF-α and interferon (IFN)-γ was investigated by reverse-transcription polymerase chain reaction
Results
title comp. enhanced and prolonged iNOS and cytokine mRNA expressions; production of IFN-γ mRNA was stimulated
Citation
Radtke, Oliver A.; Kiderlen, Albrecht F.; Kayser, Oliver; Kolodziej, Herbert
Planta Medica, 2004 , vol. 70, # 10 p. 924 - 928 Title/Abstract Full Text View citing articles Show Details
Effect
Antiproliferative
Assay Description
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Target : embryo 3T3-L1 pre-adipocytes BCRC 60159 Bioassay : cultured with title comp. for 24, 48, and 72 h at 37 deg C; cell population growth determined by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide colorimetric assay
Results
title comp. showed conc.- and time-dependent inhibition of cell population growth of cells; fig.
Citation
Hsu, Chin-Lin; Lo, Wen-Hsieh; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7359 - 7365 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
Effect : DPPH radical scavenging Bioassay : 2,2-diphenyl-1-picrylhydrazyl DPPH: 2,2-diphenyl-1-picrylhydrazyl; DPPH method
Results
activity rate ~ 70 percent
Citation
Naz, Shahina; Siddiqi, Rahmanullah; Saeed, Syed Muhammad Ghufran; Sayeed, Syed Asad
Pakistan Journal of Scientific and Industrial Research, 2012 , vol. 55, # 1 p. 14 - 20 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus platelet-rich plasma cell
Assay Description
Effect : ADP-induced platelet aggregation Species : Sprague-Dawley rat platelet poor plasma-adjusted test system used; ADP: adenosine 5'-diphosphate
Citation
Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook
Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus platelet-rich plasma cell
Assay Description
Effect : collagen-induced platelet aggregation Species : Sprague-Dawley rat platelet poor plasma-adjusted test system used
Citation
Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook
Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details
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Biological material
Rattus norvegicus platelet-rich plasma cell
Assay Description
Effect : sodium arachidonate-induced platelet aggregation Species : Sprague-Dawley rat platelet poor plasma-adjusted test system used
Citation
Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook
Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : blood coagulation Bioassay : plasma control values: 12.9 s (PT), 18.8 s (TT), 32.3 s (aPTT)
Results
PT prothrombin time 13.2 s
Citation
Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook
Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details
Effect
Immunostimulant
Assay Description
Effect : NO production Bioassay : murine macrophage-like RAW 246.7 cells
Results
NO concentration at 250 μmol/l 7 μmol/l
Citation
Kolodziej, Herbert; Radtke, Oliver A.; Kiderlen, Albrecht F.
Phytochemistry, 2008 , vol. 69, # 18 p. 3103 - 3110 Title/Abstract Full Text View citing articles Show Details
Effect
Immunostimulant
Assay Description
Effect : NO production Target : infected with Leishmania amastigotes Bioassay : murine macrophage-like RAW 246.7 cells
Results
NO concentration ~ 30 μmol/l
Citation
Kolodziej, Herbert; Radtke, Oliver A.; Kiderlen, Albrecht F.
Phytochemistry, 2008 , vol. 69, # 18 p. 3103 - 3110 Title/Abstract Full Text View citing articles Show Details
Effect
Anti-Leishmaniasis
Assay Description
Effect : antileishmanial Target : infected with Leishmania amastigotes Bioassay : murine macrophage-like RAW 246.7 cells
Results
reduction in intracellular parasite survival 50 percent
Citation
Kolodziej, Herbert; Radtke, Oliver A.; Kiderlen, Albrecht F.
Phytochemistry, 2008 , vol. 69, # 18 p. 3103 - 3110 Title/Abstract Full Text View citing articles Show Details
Biological material
human K-562 cell line
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Assay Description
Tail extent moment was determined in human K562 cells after exposition to 800 ug/ml of compound for 24 h by Comet assay
Results
TEM not calculated
Citation
Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; DijouxFranca, Marie-Genevieve; Chekir-Ghedira, Leila
Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicusliver
Assay Description
Inhibitory effects on lipid peroxidation in rat liver microsome; Significant inhibitory effect
Citation
TAKUO OKUDA; TAKASHI YOSHIDA; TSUTOMU HATANO
Journal of natural products, 1989 , vol. 52, # 1 p. 1 - 31 Title/Abstract Full Text Show Details
Biological material
Tobacco budworm larva
Assay Description
Inhibition of tobacco budworm larval growth; ED50 determined as of diet
Citation
Nicollier,G.; Thompson,A.C.
J. Nat. Prod., 1983 , vol. 46, p. 112 Title/Abstract Full Text Show Details
Assay Description
Compound useful in the teratment of diabetes
Citation
G. Zareba; N. Serradell; R. Castaner; S.L. Davies; J. Prous; N. Mealy
Drugs of the future, 2005 , vol. 30, # 12 p. 1253 - 1282 Title/Abstract Full Text Show Details
Biological material
Rattus norvegicus L6
Assay Description
Selectivity of the compound towards inhibitory concentration against rat skeletal L6 cells to that of inhibitory concentration against Trypanosoma brucei rhodesiense STIB 900
Citation
Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter
Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details
Target
Cystic fibrosis transmembrane conductance regulator:Wild
Assay Description
Ability to modulate the extracellular transport of thiol containing compound by increasing the activity of cystic fibrosis transmembrane conductance regulator
Citation
Day, Brian J.; Velsor, Leonard W.
Patent: US2004/87527 A1, 2004 ; Title/Abstract Full Text Show Details
Target
Polyphenol Oxidase D [peach]:Wild
Biological material
peach VAR. CORTEZ
Assay Description
Specific activity towards Prunus persica var. Cortez Polyphenol oxidase D at 30 degree C with 9.3 mM compound in 0.1 M citrate-0.2 M phosphate buffer, pH 6.8
Results
Specific activity not calculated
Citation
THOMAS C. WONG; BOR S. LUH; JOHN R. WHITAKER
Plant physiology, 1971 , vol. 48, # 1 p. 19 - 23 Title/Abstract Full Text Show Details
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Target
Polyphenol Oxidase C [peach]:Wild
Biological material
peach VAR. CORTEZ
Assay Description
Specific activity towards Prunus persica var. Cortez Polyphenol oxidase C at 30 degree C with 9.3 mM compound in 0.1 M citrate-0.2 M phosphate buffer, pH 6.8
Results
Specific activity not calculated
Citation
THOMAS C. WONG; BOR S. LUH; JOHN R. WHITAKER
Plant physiology, 1971 , vol. 48, # 1 p. 19 - 23 Title/Abstract Full Text Show Details
Target
Polyphenol Oxidase B [peach]:Wild
Biological material
peach VAR. CORTEZ
Assay Description
Specific activity towards Prunus persica var. Cortez Polyphenol oxidase B at 30 degree C with 9.3 mM compound in 0.1 M citrate-0.2 M phosphate buffer, pH 6.8
Results
Specific activity not calculated
Citation
THOMAS C. WONG; BOR S. LUH; JOHN R. WHITAKER
Plant physiology, 1971 , vol. 48, # 1 p. 19 - 23 Title/Abstract Full Text Show Details
Target
Polyphenol Oxidase A [peach]:Wild
Biological material
peach VAR. CORTEZ
Assay Description
Specific activity towards Prunus persica var. Cortez Polyphenol oxidase A at 30 degree C with 9.3 mM compound in 0.1 M citrate-0.2 M phosphate buffer, pH 6.8
Results
Specific activity not calculated
Citation
THOMAS C. WONG; BOR S. LUH; JOHN R. WHITAKER
Plant physiology, 1971 , vol. 48, # 1 p. 19 - 23 Title/Abstract Full Text Show Details
Assay Description
Inhibitory concetration against NO released by morpholino sydononimine
Results
NT = not tested
Citation
Yanovsky, Inessa; Finkin-Groner, Efrat; Zaikin, Andrey; Lerman, Lena; Shalom, Hila; Zeeli, Shani; Weill, Tehilla; Ginsburg, Isaac; Nudelman, Abraham; Weinstock, Marta
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10700 - 10715 Title/Abstract Full Text View citing articles Show Details
Effect
scavenging
Assay Description
Oxygen radical absorbance capacity of the compound in relative to 1 uM Trolox equivalent
Results
OXYGEN RADICAL ABSORBANCE CAPACITY not calculated
Citation
Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.
Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details
Target
glucose oxidase:Wild
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Assay Description
Inhibitory concentration of the compound against glucose oxidase
Results
NT = not tested
Citation
Yanovsky, Inessa; Finkin-Groner, Efrat; Zaikin, Andrey; Lerman, Lena; Shalom, Hila; Zeeli, Shani; Weill, Tehilla; Ginsburg, Isaac; Nudelman, Abraham; Weinstock, Marta
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10700 - 10715 Title/Abstract Full Text View citing articles Show Details
Effect
radical scavenging
Assay Description
Effective concentration of the compound required for scavenging of free radical DPPH upon incubation for 15 minutes at RT was determined
Citation
Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.
Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details
Target
Sulfotransferase [zebra fish]:Wild
Biological material
zebra fish
Assay Description
Specific activity of compound against recombinant zebrafish SULT2 cytosolic Sulphotransferase using 14uM [35S]PAPS as radioligand in 25ul of 50 mM potassium phosphate buffer, pH 7.0 upon incubation for 2 min at 100 degree C
Results
Specific activity not calculated
Citation
Sugahara, Takuya; Yang, Yuh-Shyong; Liu, Chau-Ching; Pai, T. Govind; Liu, Ming-Cheh
Biochemical Journal, 2003 , vol. 375, # 3 p. 785 - 791 Title/Abstract Full Text View citing articles Show Details
Target
Reverse transcriptase [Human immunodeficiency virus 1]:Mutated
Substance action on target
Inhibitor
Biological material
Human immunodeficiency virus 1
Assay Description
Inhibitory concentration against A17 double mutant (K103N Y181C) HIV-1 reverse transcriptase (90 nM) polymerization using [3H]dGTP (20 uM) as radioligand and poly rC/dG12-18 as template primer upon incubation for 15 min at 37 degree C, pH 7.6
Results
ND
Citation
Tillekeratne; Sherette; Grossman; Hupe; Hudson
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 20 p. 2763 - 2767 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect of collagen cross-linking by hydro thermal shrinkage temperature was determined in skin collagen matrices with compound dissolved in glycerol upon incubation for 48 h
Results
Shrinkage temperatur not calculated
Citation
Halkes, S Bart A; Vrasidas, Ioannis; Rooijer, Gilbert R; van den Berg, Albert J J; Liskamp, Rob M J; Pieters, Roland J
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 12 p. 1567 - 1570 Title/Abstract Full Text Show Details
Effect
Antineoplastic
Biological material
U-251MG cell line
Assay Description
Inhibitory concentration of the compound against growth of human U251n cell line
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Results
ND = Not determined
Citation
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
Target
Carbonic anhydrase 2 [human]:Wild
Biological material
human
Assay Description
In vitro binding affinity of the compound towards Human Carbonic anhydrase 2 using 4-nitrophenylacetate as substrate
Results
Competitive
Citation
Guelcin, Ilhami; Beydemir, Suekrue
Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 408 - 430 Title/Abstract Full Text View citing articles Show Details
Target
Carbonic anhydrase 1 [human]:Wild
Biological material
human
Assay Description
In vitro binding affinity of the compound towards Human Carbonic anhydrase 1 using 4-nitrophenylacetate as substrate
Results
Competitive
Citation
Guelcin, Ilhami; Beydemir, Suekrue
Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 408 - 430 Title/Abstract Full Text View citing articles Show Details
Effect
Antineoplastic
Biological material
U-87
Assay Description
Inhibitory concentration of the compound against growth of human U-87 cell line
Results
ND = Not determined
Citation
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
Substance action on target
Inhibitor
Biological material
KB
Assay Description
Inhibitory concentration of the compound against growth of human KB cell line
Results
ND = Not determined
Citation
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
Substance action on target
Inhibitor
Biological material
Huh-7 cell line
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Assay Description
Inhibitory concentration of the compound against growth of human Huh-7 cell line
Results
ND = Not determined
Citation
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
Target
72kDa type IV collagenase:Wild
Assay Description
Ligand efficiency of the compound against MATRIX METALLOPROTEINASE 2 was determined
Results
LIGAND EFFICIENCY not calculated
Citation
Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo
Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details
Assay Description
Antioxidant activity of the compound against meadowsweet extract upon incubation in 70% Ethanol in Relation to Oxygen Electroreduction
Results
Antioxidant acitivity not calculated
Citation
Shilova; Semenov; Suslov; Korotkova; Vtorushina; Belyakova
Pharmaceutical Chemistry Journal, 2009 , vol. 43, # 4 p. 185 - 190 Title/Abstract Full Text View citing articles Show Details
Effect
scavenging
Assay Description
Inhibitory concentration of the compound against DPPH radical scavenging upon incubation for 20 mins at RT in the dark
Citation
Das, Sreeparna; Mitra, Indrani; Batuta, Shaikh; Niharul Alam, Md.; Roy, Kunal; Begum, Naznin Ara
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 21 p. 5050 - 5054 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Citation
BAYLOR COLLEGE OF MEDICINE; Chen, Changyi; Lu, Jian-Ming; Yao, Qizhi
Patent: US2014/163045 A1, 2014 ; Title/Abstract Full Text Show Details
Effect
Antioxidant
Citation
Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul
Acta Poloniae Pharmaceutica - Drug Research, 2015 , vol. 72, # 6 p. 1201 - 1215 Title/Abstract Full Text View citing articles Show Details
Biological material
chicken
Citation
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Effect
Phagocytic
Biological material
Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028
Citation
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
In vivo: Animal Model (453) Quantitative Results pX
Parameter
Value (qual)
Value (quant)
Unit
Action on Target
Animal Model
Biological Species
Route of administration
Dose
Concentration
16.68
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Dosing regimen
Effect
Reference (expand all/collapse all)
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
18.48
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
19.87
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
26.43
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
23.45
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
16.47
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
12.12
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
14.1
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
16.39
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
14.1
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
42.21
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
49.81
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
34.83
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
56.97
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
34.49
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
47.76
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
33.18
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
51
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
32.51
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
47.52
mmol/mg
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
pX
Parameter Concentration
Value (qual)
Value (quant)
Unit
26.54
mmol/mg
Action on Target
Animal Model
Biological Species
Route of administration
Dose
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Dosing regimen
Effect
Reference (expand all/collapse all)
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
43.12
mmol/mg
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
44.59
mmol/mg
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
53.86
mmol/mg
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
27.25
mmol/mg
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.59
mmol/mg
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.56
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.67
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.6
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.57
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.52
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.47
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.49
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.75
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
0.66
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
44.84
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
54.26
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
49.52
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
40.79
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Concentration
50.89
mmol/mg
Rattus norvegicus
intragastric administration
50 mg/kg
Investigational New Drug...
Title/Abstract Full Text View citing articles Show Details
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
NOAEC
5000
mg/kg
Mus musculus
oral administration
5000 mg/kg
Toxic : Acute
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Rajalakshmi; Devaraj; Niranjali Devaraj
Food and Chemical Toxicology, 2001 , vol. 39, # 9 p. 919 - 922 Title/Abstract Full Text View citing articles Show Details
TGI %
16 - 35
%
Mus musculus
intraperitoneal administration
20 mg/kg
Antineoplastic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bin-Chuan; Hsu, Wu-Huei; Yang, Jai-Sing; Hsia, Te-Chun; Lu, Chi-Cheng; Chiang, Jo-Hua; Yang, Jiun-Long; Lin, Ching-Hsiung; Jen-jyh; Lee-jen, Wu Suen; Wellington, Gibson Wood; Chung, Jing-Gung
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 16 p. 7596 - 7604 Title/Abstract Full Text View citing articles Show Details
Length
=
89.9
mm
Rattus norvegicus
oral administration
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Sugimoto, Sachiko; Chi, Guihua; Kato, Yasuyo; Nakamura, Seikou; Matsuda, Hisashi; Yoshikawa, Masayuki
Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 3 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details
T/C (%)
=
139
%
Mus musculus
intraperitoneal administration
Cancer Research, 1979 , ...
Title/Abstract Full Text Show Details
Mus musculus
intraperitoneal administration
Cancer Research, 1979 , ...
Title/Abstract Full Text Show Details
Mus musculus
intraperitoneal
Cancer Research, 1979 , ...
Elford; Wampler; Van 'T Riet
Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details
Dose
=
1500
mg/kg
Elford; Wampler; Van 'T Riet
Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details
Dose
=
7.8
mmol/kg
administration
Title/Abstract Full Text Show Details
Elford; Wampler; Van 'T Riet
Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details
Mus musculus
intraperitoneal administration
Current Medicinal Chemis...
Title/Abstract Full Text View citing articles Show Details
Lamoral-Theys; Pottier; Dufrasne; Neve; Dubois; Kornienko; Kiss; Ingrassia
Current Medicinal Chemistry, 2010 , vol. 17, # 9 p. 812 - 825 Title/Abstract Full Text View citing articles Show Details
% Inhibition
31
%
experimental ear inflammation
Mus musculus
topical administration
1 mg
Single
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
% Decrease
Active
experimental metabolic disorder
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
50 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
50 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
50 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% Decrease
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% Decrease
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% Decrease
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% Decrease
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% Decrease
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% Decrease
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% Decrease
Active
experimental metabolic disorder
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
C57BL 6 mouse
oral administration
100 mg/kg
Anti-Metabolic disorder
Patent: US2015/174087 ...
Title/Abstract Full Text Show Details
stroke prone spontaneously hypertensive rat
oral administration
40 mg/kg bw
Antihypertensive
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% Decrease
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% increase
Active
experimental metabolic disorder
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
% decrease
87.2
%
experimental hypertension
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
% decrease
78.4
%
experimental hypertension
stroke prone spontaneously hypertensive rat
oral administration
40 mg/kg bw
Antihypertensive
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
3
% Inhibition
Active
zebra fish
1 mM
Anti-Melanogenesis
Patent: WO2016/14529 A...
Title/Abstract Full Text Show Details
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
WISYS TECHNOLOGY FOUNDATION, INC.; HUANG, Cheng-Chen; MONTE, Aaron P.
Patent: WO2016/14529 A1, 2016 ; Title/Abstract Full Text Show Details
Amount increase
Active
streptozotocininduced diabetes
mellitus
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
% increase
Not active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
1
Amount increase
Not active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount increase
Active
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
138.4
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
104.8
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
91.9
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
124.2
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
104.3
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
98.2
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
123.2
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
129.5
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
279.5
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
221.6
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
152.6
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
124.5
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
112.2
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
118.3
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
16.2
μU/ml
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
16.1
μU/ml
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
84.6
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
78.6
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
92.4
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
86.9
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
HOMA
4.8
no unit
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
HOMA
5.1
no unit
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
21.8
μU/ml
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
16.4
μU/ml
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
114.6
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
78.8
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
171.4
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216
Title/Abstract Full Text View citing articles Show Details
Concentration
91.2
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
HOMA
15.1
no unit
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
HOMA
5.1
no unit
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
116.6
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
189.2
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
142.5
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
208.6
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
291.4
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
216.3
mg/dl
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
191.5
mg/dl
streptozotocin-
Wistar rat
intragastric
20
Repeated
Antidiabetic
European Journal of Phar...
induced diabetes mellitus
administration
mg/kg
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Concentration
134.2
mg/dl
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount
7.4
U/mg protein
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount
0.2
U/mg protein
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount
0.4
U/mg protein
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount
23.2
mg/g tissue
Wistar rat
intragastric administration
20 mg/kg
Repeated
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount
7.2
U/mg protein
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount
0.2
U/mg protein
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount
0.4
U/mg protein
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Amount
21.4
mg/g tissue
streptozotocininduced diabetes mellitus
Wistar rat
intragastric administration
20 mg/kg
Repeated
Antidiabetic
European Journal of Phar...
Title/Abstract Full Text View citing articles Show Details
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
5.7
% decrease
Active
chicken
2 - 14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.22
% increase
Active
chicken
6 - 14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.22
% increase
Active
chicken
6 - 14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.22
% decrease
Active
chicken
6 - 10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Fold-decrease
2
no unit
chicken
14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.7
% Inhibition
Active
chicken
2 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.22
% Inhibition
Active
chicken
6 - 14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.7
% decrease
Active
chicken
2 - 14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.7
% decrease
Active
chicken
2 - 14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
0.05 - 0.118
nmol/μl
chicken
2 - 14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
0.1
mM
chicken
6 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
0.34
mM
chicken
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
0.44
mM
chicken
14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
190
mU/ml
chicken
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
310
mU/ml
chicken
6 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
420
mU/ml
chicken
2 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
87
mU/ml
chicken
14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
10
μmol/mg protein
chicken
14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
17
μmol/mg protein
chicken
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
27
μmol/mg protein
chicken
2 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
4.2
μmol/mg protein
chicken
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
4.55
μmol/mg protein
chicken
14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
455
pg/ml
chicken
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Amount
795
pg/ml
chicken
14 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
100
%
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
% decrease
Low
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
3.23
% Increase
Active
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
fold
2.07
no unit
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93
Title/Abstract Full Text View citing articles Show Details
3.23
% Increase
Active
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
Mortality rate
60
%
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
Mortality rate
80
%
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
% decrease
3.96
%
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
% decrease
3.25
%
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
% decrease
3.96
%
experimental infection
Institute for Cancer Research mouse
oral administration
100 μg/ml
Antibiotic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
% Decrease
Active
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
% Increase
Active
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Concentration
118.83
mg/dl
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Amount
6.5
%
nicotinamide-
albino rat
oral
20
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
streptozotocin induced diabetes mellitus
administration
mg/kg
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Amount
17.81
μIU/ml
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
HOMA-IR
5.15
no unit
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Amount
44.03
pg/ml
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Amount
0.01619
K
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Amount
0.6576
mU
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Amount
1.1556
U
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Lipid peroxidation
0.1212
nmol
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Concentration
0.1417
nmol
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Amount
0.8202
nmol
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Amount
9.53
U/g
nicotinamidestreptozotocin induced diabetes mellitus
albino rat
oral administration
20 mg/kg
Repeated
Antineurodegenerative
Metabolic Brain Disease,...
Title/Abstract Full Text View citing articles Show Details
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
1
% reduction
Not active
lipopolysaccharideinduced endotoxemia
C57BL 6 mouse
intraperitoneal administration
20 mg/kg bw
Repeated
Protective
Patent: WO2017/66965 A...
Title/Abstract Full Text Show Details
lipopolysaccharideinduced endotoxemia
C57BL 6 mouse
Antiinflammatory
Patent: WO2017/66965 A...
Title/Abstract Full Text Show Details
lipopolysaccharideinduced endotoxemia
C57BL 6 mouse
Antiinflammatory
Patent: WO2017/66965 A...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
THE UNIVERSITY OF HONG KONG; RONG, Jianhui
Patent: WO2017/66965 A1, 2017 ; Title/Abstract Full Text Show Details
1
% decrease
Not active
THE UNIVERSITY OF HONG KONG; RONG, Jianhui
Patent: WO2017/66965 A1, 2017 ; Title/Abstract Full Text Show Details
1
% decrease
Not active
THE UNIVERSITY OF HONG KONG; RONG, Jianhui
Patent: WO2017/66965 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
145
g/l
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
count
1200000000
cell/l
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
137
g/l
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
count
1200000000
cell/l
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Pressure
71
mmHg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Amount
0.12
l/min/kg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
SVRI
1673
dyn*s*cm5
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Pressure
11.6
mmHg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
heart rate
125
no unit
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Pressure
60
mmHg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Amount
0.13
l/min/kg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
SVRI
1478
dyn*s*cm5
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Pressure
11.3
mmHg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
heart rate
127
no unit
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
% Increase
Active
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
% Increase
Active
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
1
% change
Not active
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
pX
Parameter
Value (qual)
% Change
Low
Value (quant)
Unit
Action on Target
Animal Model
Biological Species
Route of administration
Dose
Dosing regimen
Effect
Reference (expand all/collapse all)
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
% decrease
Active
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Pressure
22
mmHg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Pressure
53
mmHg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
pH
7.17
no unit
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Pressure
23
mmHg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Pressure
54
mmHg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
pH
7.12
no unit
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
% decrease
Active
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
1
% Increase
Not active
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
0.75
nmol/l
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
0.8
mmol/l
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
41
ng/l
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
344
IU
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
4573
IU
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
8.1
mmol/l
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Creatinine clearance
30
ml/min
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Amount
5.5
no unit
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
407
IU
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
6273
IU
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
7.5
mmol/l
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Creatinine clearance
24
ml/min
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Amount
6.2
no unit
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
344
IU
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
407
IU
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
315
IU
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
409
IU
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
25
pg/mg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Amount
2.44
μmol/min/mg protein
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Concentration
69
ng/l
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Amount
22
ml/min/kg
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Amount
26
ml/min/kg
experimental sepsis
Canine
Patent: US2017/128398 ...
Title/Abstract Full Text Show Details
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul
Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details
Rate
245.75
bpm
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Rate
241.25
bpm
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
23
ms
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
26.25
ms
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
47.75
ms
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
40.25
ms
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
19.75
ms
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
18
ms
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
57.25
ms
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
79
ms
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
120.67
ms
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Time
150.33
ms
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
R height
0.22
mV
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
R height
0.24
mV
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
7.28
μmol/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
7.6
μmol/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
15.41
μmol/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
15.38
μmol/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
0.17
μmol/l
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
0.19
μmol/l
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
8.82
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
8.04
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
15.42
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
15.94
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
0.71
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
0.88
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
0.17
mmol/min/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
0.14
mmol/min/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
61.19
μmol/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
61.17
μmol/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
38.43
μmol/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
39.37
μmol/mg protein
Diazinon-induced cardiac oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
64.63
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
64.33
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
33.02
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
33.18
μmol/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
0.194
mmol/min/mg protein
Diazinon-induced renal oxidative
Wistar rat
oral administration
120 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
stress
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
0.191
mmol/min/mg protein
Diazinon-induced renal oxidative stress
Wistar rat
oral administration
60 mg/kg
Repeated
Antioxidant
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
0.55
unit/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
0.58
unit/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
157.21
unit/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
121.42
unit/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
294.4
unit/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Activity
266.8
unit/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Weight
0.35
g
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Weight
0.41
g
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Weight
0.77
g
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Weight
0.81
g
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
%
33.24
%
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
%
34.07
%
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
8.11
g/dl
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
10.37
g/dl
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
5010000000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
6840000000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Volume
49.81
fl
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Volume
66.35
fl
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
15.16
pg
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
16.19
pg
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
30430000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
24390000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
10530000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Concentration
10190000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
6030000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
6110000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
100000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
100000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
4220000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
3920000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
100000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
100000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
10000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
60 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
Amount
10000000
cell/l
Diazinon-induced toxicity
Wistar rat
oral administration
120 mg/kg
Repeated
Protective
Interdisciplinary Toxico...
Title/Abstract Full Text View citing articles Show Details
Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex
Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details
% decrease
Active
experimental candidiasis
Institute for Cancer Research mouse
intraperitoneal administration
Institute for Cancer Research mouse
intraperitoneal administration
20 - 80 mg/kg
Repeated
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
%
0
%
experimental candidiasis
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
80 mg/kg
Repeated
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
%
33.3
%
experimental candidiasis
Institute for Cancer Research mouse
intraperitoneal administration
Institute for Cancer Research mouse
intraperitoneal administration
Institute for Cancer Research mouse
intraperitoneal administration
Institute for Cancer Research mouse
intraperitoneal administration
Institute for Cancer Research mouse
intraperitoneal administration
Wistar rat
oral administration
20 mg/kg
Repeated
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
%
8.3
%
experimental candidiasis
40 mg/kg
Repeated
Antifungal
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
Weight
24.61
g
experimental candidiasis
80 mg/kg
Repeated
Body Weight
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
Weight
21.76
g
experimental candidiasis
20 mg/kg
Repeated
Body Weight
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
Weight
25.35
g
experimental candidiasis
40 mg/kg
Repeated
Body Weight
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
%
-22.23
%
Nmethylnitrosoureainduced colon cancer
50 mg/kg bw
Repeated
50 mg/kg bw
Repeated
50 mg/kg bw
Repeated
50 mg/kg bw
Repeated
50mg/kg
Repeated
Antineoplastic
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Attia, Naglaa A.; Sayed, Alaa H.; Mahmoud, Nadia S.; Ahmed, Hanaa H.
Medicinal Chemistry Research, 2017 , vol. 26, # 10 p. 2614 - 2623 Title/Abstract Full Text View citing articles Show Details
%
-19.09
%
Nmethylnitrosoureainduced colon cancer
Wistar rat
oral administration
Antineoplastic
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Attia, Naglaa A.; Sayed, Alaa H.; Mahmoud, Nadia S.; Ahmed, Hanaa H.
Medicinal Chemistry Research, 2017 , vol. 26, # 10 p. 2614 - 2623 Title/Abstract Full Text View citing articles Show Details
Concentration
1691.5
pg/ml
Nmethylnitrosoureainduced colon cancer
Wistar rat
oral administration
Antineoplastic
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Attia, Naglaa A.; Sayed, Alaa H.; Mahmoud, Nadia S.; Ahmed, Hanaa H.
Medicinal Chemistry Research, 2017 , vol. 26, # 10 p. 2614 - 2623 Title/Abstract Full Text View citing articles Show Details
Concentration
5.17
ng/ml
Nmethylnitrosoureainduced colon cancer
Wistar rat
oral administration
Antineoplastic
Medicinal Chemistry Rese...
Title/Abstract Full Text View citing articles Show Details
Attia, Naglaa A.; Sayed, Alaa H.; Mahmoud, Nadia S.; Ahmed, Hanaa H.
Medicinal Chemistry Research, 2017 , vol. 26, # 10 p. 2614 - 2623 Title/Abstract Full Text View citing articles Show Details
Fold-increase
4.7
no unit
Wistar rat
oral administration
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Fold-increase
5.5
no unit
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Fold-increase
5
no unit
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Fold-increase
4.4
no unit
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Fold-increase
5.1
no unit
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Fold-increase
4.9
no unit
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Fold-increase
1.6
no unit
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Papp (transport)
3.5E-06
cm/s
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Papp (transport)
4.1E-06
cm/s
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Papp (transport)
4.4E-06
cm/s
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448
Title/Abstract Full Text View citing articles Show Details
Concentration
11.7
μg/ml
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Concentration
12.7
μg/ml
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
Concentration
13.5
μg/ml
Wistar rat
oral administration
50mg/kg
Repeated
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Athukuri, Bhargavi Latha; Neerati, Prasad
Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details
5
% Inhibition
Active
zebra fish
10 μM
Skin whitening
Patent: US2017/342047 ...
Title/Abstract Full Text Show Details
WISYS TECHNOLOGY FOUNDATION, INC.; Huang, Cheng-Chen; Monte, Aaron P.
Patent: US2017/342047 A1, 2017 ; Title/Abstract Full Text Show Details
Qualitative Information 1 of 104
2 of 104
3 of 104
Biological material
goose
Assay Description
Effect : avian influenza; protection from Example 54 Examples 33 to 50 are repeated except that in Example 17 one hundred geese, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the geese, and not the chickens, are utilized.
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Hensley, Charles; Pyo, Sung
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
chicken
Assay Description
Effect : avian influenza; protection from Example 39 Example 33 is repeated except that each ten pounds of primary conventional chicken feed is admixed with two tablespoons of the aqueous medicament composition of Example 7 to produce the resulting medicament composition-primary chicken feed mixture that is administered to the test group. Similar
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Hensley, Charles; Pyo, Sung
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
turkey (bird)
Assay Description
Effect : avian influenza; protection from Example 51 Examples 33 to 50 are repeated except that in Example 17 one hundred turkeys, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the turkeys, and not the chickens, are utilized.
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
4 of 104
5 of 104
6 of 104
Citation
Hensley, Charles; Pyo, Sung
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
duck
Assay Description
Effect : avian influenza; protection from Example 52 Examples 33 to 50 are repeated except that in Example 33 one hundred ducks, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the ducks, and not the chickens, are utilized.
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Hensley, Charles; Pyo, Sung
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : avian influenza; protection from Species : pheasant Example 53 Examples 33 to 50 are repeated except that in Example 17 one hundred pheasants, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the pheasants, and not the chickens, are utilized.
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Hensley, Charles; Pyo, Sung
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antiallergic
Assay Description
7 of 104
Results
at 0.05/0.13 mg/ear title comp. inhibited oxazolone-induced type IV allergy by 8.3/29.5 percent (vs 73.2/83.8 percent for hydrocortisone)
Citation
Suzuki, Masazumi; Yoshino, Kyoji; Maeda-Yamamoto, Mari; Miyase, Toshio; Sano, Mitsuaki
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 11 p. 5649 - 5653 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Assay Description
8 of 104
Target : ICR mouse Bioassay : 24 h later sacrificed; circular parts of both ears removed and their weights measured; ear swelling ratio determined; hydrocortisone used as reference comp. in vivo; inhibition of oxazoloneinduced type IV allergy examined; 5 mice (4 wks) sensitized by application of 0.5 percent oxazolone solution (OS) to skin of abdominal region; 5 d later challenged by application of OS to both sides of mouse's right ear
Target : senescence accelerated mouse Bioassay : 9-month-old mice were treated; CAT: catalase; GPx: glutathione peroxidase; LPO: lipid peroxidation; MDA: malonaldehyde; TBARS: thiobarbituric acid reactive substances; control: 0.9 percent NaCl mice received title comp.; CAT and GPx activities measured in whole blood and liver spectrophotometrically; LPO measured in liver, brain and kidney using formation of MDA according to presence of TBARS
Results
title comp. increased CAT and GPx activities and reduced extent of lipid peroxidation (diagram)
Citation
Li; Ng; Gao; Fu; Niu; Zhao; Chen; Liu
Life Sciences, 2005 , vol. 77, # 2 p. 230 - 240 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity
Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase
9 of 104
10 of 104
11 of 104
12 of 104
Results
enzyme activity 3.4 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 4.13 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase
Results
enzyme activity 4.46 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 4.31 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
13 of 104
14 of 104
15 of 104
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase
Results
enzyme activity 3.29 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 5.24 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase
Results
enzyme activity 4.31 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 7.71 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
16 of 104
17 of 104
18 of 104
19 of 104
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase
Results
enzyme activity 5.47 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
superoxide dismutase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : SOD activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 5.32 u/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
enzyme activity 41.85 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;Caecum
Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
20 of 104
21 of 104
22 of 104
Results
enzyme activity 36.03 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
enzyme activity 43.72 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 41.58 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
enzyme activity 45.58 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
23 of 104
24 of 104
25 of 104
26 of 104
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 44.06 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
enzyme activity 51.52 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 37.22 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
enzyme activity 40.96 μmol H2O2 utilized/min/mg protein
27 of 104
28 of 104
29 of 104
30 of 104
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Target
catalase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Catalase activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 35.28 μmol H2O2 utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione
Results
enzyme activity 4.28 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 4.2 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione
Results
enzyme activity 4.27 mmol GSH utilized/min/mg protein
31 of 104
32 of 104
33 of 104
34 of 104
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 3.39 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione
Results
enzyme activity 5.46 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 3.17 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione
Results
enzyme activity 7.69 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
35 of 104
36 of 104
37 of 104
38 of 104
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 7.7 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione
Results
enzyme activity 5.53 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione peroxidase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione peroxidase activity enzyme activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 5.51 mmol GSH utilized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;
Results
enzyme activity 10.96 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
39 of 104
40 of 104
41 of 104
42 of 104
43 of 104
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 6.97 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;
Results
enzyme activity 12.04 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 11.54 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;
Results
enzyme activity 11.64 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
44 of 104
45 of 104
46 of 104
47 of 104
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 11.04 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;
Results
enzyme activity 21.26 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
enzyme activity 18.9 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;
Results
enzyme activity 12.36 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Target
Glutathione reductase:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : Glutathione reductase activity enzyme activity Target : ;proximal colon
Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
48 of 104
49 of 104
50 of 104
51 of 104
52 of 104
Results
enzyme activity 12.06 mmol NADPH oxidized/min/mg protein
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 1.58 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 1.61 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 1.92 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 2.01 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
53 of 104
54 of 104
55 of 104
56 of 104
Assay Description
Effect : Vitamin C level Target : Vitamin C ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 1.58 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 2.15 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 1.95 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 1.93 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 1.72 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
57 of 104
58 of 104
59 of 104
60 of 104
61 of 104
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin C level Target : Vitamin C ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 2.11 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 0.78 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 0.81 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 0.94 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 1.52 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259
Title/Abstract Full Text View citing articles Show Details
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Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 0.82 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 0.88 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 1.44 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 0.98 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil
Results
concentration 0.86 mg/100 g tissue
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Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : Vitamin E level Target : Vitamin E ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine
Results
concentration 1.92 mg/100 g tissue
Citation
Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam
Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : |biotransformation Target : Wister rats Bioassay : metabolite levels in serum and urinary excretion determined 3-6 rats (4 weeks, 259-304 g)/group kept in air conditioned room (23 deg C, 50-66 percent humidity, 12 h light/dark cycle) with free access to food and water; blood and urine collected at predetermined times
Citation
Nakamura, Yumiko; Tonogai, Yasuhide
Journal of Agricultural and Food Chemistry, 2003 , vol. 51, # 24 p. 7215 - 7225 Title/Abstract Full Text View citing articles Show Details
Assay Description
Effect : avian influenza; protection from Target : pheasant Bioassay : Example 53 Examples 33 to 50 are repeated except that in Example 17 one hundred pheasants, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the pheasants, and not the chickens, are utilized.
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Sung, Pyo; Charles, Hensley
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
goose
Assay Description
Effect : avian influenza; protection from Bioassay : Example 54 Examples 33 to 50 are repeated except that in Example 17 one hundred geese, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the geese, and not the chickens, are utilized.
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Sung, Pyo; Charles, Hensley
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
chicken
Assay Description
Effect : avian influenza; protection from Bioassay : Example 39 Example 33 is repeated except that each ten pounds of primary conventional chicken feed is admixed with two tablespoons of the aqueous medicament composition of Example 7 to produce the resulting medicament composition-primary chicken feed mixture that is administered to the test group. Similar
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Sung, Pyo; Charles, Hensley
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
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Biological material
turkey (bird)
Assay Description
Effect : avian influenza; protection from Bioassay : Example 51 Examples 33 to 50 are repeated except that in Example 17 one hundred turkeys, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the turkeys, and not the chickens, are utilized.
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Sung, Pyo; Charles, Hensley
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
duck
Assay Description
Effect : avian influenza; protection from Bioassay : Example 52 Examples 33 to 50 are repeated except that in Example 33 one hundred ducks, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the ducks, and not the chickens, are utilized.
Results
treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza
Citation
Sung, Pyo; Charles, Hensley
Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : |pharmacokinetics Bioassay : in situ gastric absorption tested anesthetized rats starved for 5-8 h; pylorus ligated; portal vein and abdominal aorta blood withdrawn at 5, 15, and 25 min post dosing; total, intact, and conjugated title comp. levels in plasma determined by HPLC-ECD method
Results
at 5 min after administration, plasma conc. of intact and conjugated title comp. in the portal vein/abdominal artery were 0.45/0.05 and 0.09/0.16 μmol/l, respectively
Citation
Konishi, Yutaka; Zhao, Zhaohui; Shimizu, Makoto
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 20 p. 7539 - 7543 Title/Abstract Full Text View citing articles Show Details
Effect
Neuroprotective
Biological material
Rattus norvegicus
Assay Description
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Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control rats received title comp. alone or with Fe-NTA injection; 12 h after last treatment, blood sampled; serum levels of creatinine and hydrogen peroxide (H2O2) and level of blood urea nitrogen (BUN) measured
Results
title comp. alone had no effect but significantly and dose-dependently attenuated by 29-35%, 74-88% and 30-40%, resp., Fe-NTA-induced increase in BUN, serum creatinine and H2O2 (table)
Citation
Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat
Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : DNA synthesis; inhibition of Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control rats received title comp. alone or with Fe-NTA; 18 h after Fe-NTA injection, <3H>thymidine injected i.p.; 2 h later, rats sacrificed; kidneys removed; DNA synthesis as <3H>thymidine incorporation into renal DNA determined
Results
title comp. caused significant and dose-dependent reduction (by 42-70%) in Fe-NTA-induced enhancement of DNA synthesis (figure)
Citation
Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat
Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details
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Target
enzyme:Wild
Biological material
Rattus norvegicus
Assay Description
Effect : |enzyme; inhib. of Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control rats received title comp. alone/with Fe-NTA; 12 h after last treatment, rats sacrificed; kidneys removed; homogenized; postmitochondrial supernatant, microsomal fractions prepared; renal ornithine decarboxylase (ODC) activity determined
Results
title comp. alone had no effect but significantly and dose-dependently attenuated by 50-82% at 10-20 mg/kg, resp., Fe-NTA-induced increase in activity of ODC (figure)
Citation
Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat
Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
Rattus norvegicus
Assay Description
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Results
title comp. alone had no effect but significantly and dose-dependently attenuated by 15-31%, 16-33% and 17-45%, resp., Fe-NTA-induced reduction in activities of renal catalase, GPx and G6PD (table)
Citation
Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat
Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
Rattus norvegicus
Assay Description
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Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control; GSH: reduced glutathione; GST: glutathione-S-transferase; GR: glutathione reductase rats received title comp. alone/with Fe-NTA; 12 h after last treatment, rats sacrificed; kidneys removed; homogenized; postmitochondrial supernatant, microsomal fractions prepared; GSH content, activities of GSH metabolizing enzymes (GST, GR) determined
Results
title comp. alone had no effect but significantly and dose-dependently attenuated by 12-28%, 21-36% and 15-40%, resp., Fe-NTA-induced depletion of renal GSH, reduction in activities of GST and GR (table)
Citation
Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat
Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details
Effect
Antioxidant
Biological material
Rattus norvegicus
Assay Description
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Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control; GPx: glutathione peroxidase; G6PD: glucose-6-phosphate dehydrogenase rats received title comp. alone/with Fe-NTA; 12 h after last treatment, rats sacrificed; kidneys removed; ho mogenized; postmitochondrial supernatant and microsomal fractions prepared; renal antioxidant enzymes catalase, GPx and G6PD determined
Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control; QR: quinone reductase; XO: xanthine oxidase; MDA: malondialdehyde; LPO: lipid peroxidation rats received title comp. alone/with Fe-NTA; 12 h after last treatment, rats sacrificed; kidneys removed; postmitochondrial supernatant, microsomal fractions prepared; renal QR, XO and ironascorbate-induced microsomal LPO (as MDA production) determined
Results
title comp. alone had no effect but significantly and dose-dependently attenuated by 56-76 and 50-83%, and 12-34%, resp., Fe-NTA-induced increase in activity of XO and in renal microsomal LPO, and Fe-NTA-induced reduction in activity of QR (table)
Citation
Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat
Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details
Biological material
dog
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Assay Description
Effect : adverse events; occurrence of Bioassay : Experimental Example 6: Tests for safety of anhydrous gallic acid on Beagle dogs <n="14"/>[88] Tests were performed to investigate the toxicity to non-rodents, to which the anhydrous gallic acid in Example 3 is orally administered once. Male and female Beagle dogs were used for a test group, to which
Results
temporary vomiting, brownish stool diarrhea and anorexia were observed when title compound was administered
Citation
NA, Chun-Soo; KIM, Sang-Mi; CHOI, Bum-Rak; KIM, Jin-Beom; SEO, Seok-In
Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details
Assay Description
Effect : sexual hormone level; effect on Target : Sprague-Dawley (SD) rat Bioassay : Experimental Example 1: Effect of Lacquer Tree Flavonoids on Increase inSexual Hormones of Rats.[70] In this experiment, Sprague-Dawley rats weighing about 25Og were used as a control group (n=8, a no-administration group) and a test group (n=8, a group administered with the lacquer tree flavonoids
Results
title compound administration at 100 mg/kg dose caused a 2.5 fold or more increase in testosterone level; figure is given
Citation
NA, Chun-Soo; KIM, Sang-Mi; CHOI, Bum-Rak; KIM, Jin-Beom; SEO, Seok-In
Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Body Weight
Assay Description
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Citation
NA, Chun-Soo; KIM, Sang-Mi; CHOI, Bum-Rak; KIM, Jin-Beom; SEO, Seok-In
Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Toxic
Biological material
dog
Assay Description
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Bioassay : Experimental Example 6: Tests for safety of anhydrous gallic acid on Beagle dogs <n="14"/>[88] Tests were performed to investigate the toxicity to non-rodents, to which the anhydrous gallic acid in Example 3 is orally administered once. Male and female Beagle dogs were used for a test group, to which
Citation
NA, Chun-Soo; KIM, Sang-Mi; CHOI, Bum-Rak; KIM, Jin-Beom; SEO, Seok-In
Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Toxic : Subacute
Biological material
Mus musculus
Assay Description
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Target : Sprague-Dawley (SD) rat Bioassay : Experimental Example 7: Effects of Anhydrous Gallic Acid Administration onVariation in Body Weight of Male Rats[91] This experiment was performed to confirm whether long term administration of the anhydrous gallic acid obtained in Example 3 affects variation in body weight. Sprague- Dawley rats weighting
Bioassay : control: DMSO 12 mice (6/6 f/m/) 6-8 weeks old; animals were observed twice daily for the subsequent 28 days; then sacrificed following an overnight fast; autopsy was carried out on all animals; whole blood was collected
Results
no effects on body weight and organ weight (except decrease in the spleen weight); slight decrease in food intake; minor differences in hematological or histological examinations; slight but nonsignificant decrease in the hemoglobin level
Citation
Rajalakshmi; Devaraj; Niranjali Devaraj
Food and Chemical Toxicology, 2001 , vol. 39, # 9 p. 919 - 922 Title/Abstract Full Text View citing articles Show Details
Effect
Antineoplastic
Biological material
Mus musculus
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Assay Description
Effect : tumor size Species : BALB/cnu/nu mouse PDP value for tumor growth inhibition measured after treatment of title comp. from 22 to 38 days
Results
tumor weight decrease 40 %
Citation
Bin-Chuan; Hsu, Wu-Huei; Yang, Jai-Sing; Hsia, Te-Chun; Lu, Chi-Cheng; Chiang, Jo-Hua; Yang, Jiun-Long; Lin, Ching-Hsiung; Jen-jyh; Lee-jen, Wu Suen; Wellington, Gibson Wood; Chung, Jing-Gung
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 16 p. 7596 - 7604 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : antihaemorrhoidal Bioassay : Pharmacological Activity Of The Extract Antihaemorrhoidal activity The antihaemorrhoidal activity of the Euphorbia prostrcrta extract was assessed and compared with reference drug, diosmin using anorectum: body weight ratio model in rats (modified method of Jia et al., 2000). Euphorbia prostrata extract
Results
title comp. (1.123 mg/kg, 7 days) showed significant decrease in anorectum : body weight ratio as well as inflammation and redness at the site when compared to control
Citation
PANACEA BOITEC LTD.
Patent: WO2005/65696 A1, 2005 ; Title/Abstract Full Text Show Details
Effect
Body Weight
Biological material
Rattus norvegicus
Assay Description
Effect : body weight; effect on Experimental Example 7: Effects of Anhydrous Gallic Acid Administration onVariation in Body Weight of Male Rats[91] This experiment was performed to confirm whether long term administration of the anhydrous gallic acid obtained in Example 3 affects variation in body weight. Sprague- Dawley rats weighting
Citation
LIFETREE BIOTECH CO., LTD.
Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Toxic
Biological material
dog
Assay Description
Effect : toxic Experimental Example 6: Tests for safety of anhydrous gallic acid on Beagle dogs <n="14"/>[88] Tests were performed to investigate the toxicity to non-rodents, to which the anhydrous gallic acid in Example 3 is orally administered once. Male and female Beagle dogs were used for a test group, to which
Citation
LIFETREE BIOTECH CO., LTD.
Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
dog
Assay Description
Effect : adverse events; occurrence of Experimental Example 6: Tests for safety of anhydrous gallic acid on Beagle dogs <n="14"/>[88] Tests were performed to investigate the toxicity to non-rodents, to which the anhydrous gallic acid in Example 3 is orally administered once. Male and female Beagle dogs were used for a test group, to which
Results
temporary vomiting, brownish stool diarrhea and anorexia were observed when title compound was administered
Citation
LIFETREE BIOTECH CO., LTD.
Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details
Biological material
Rattus norvegicus
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Assay Description
Effect : sexual hormone level; effect on Experimental Example 1: Effect of Lacquer Tree Flavonoids on Increase inSexual Hormones of Rats.[70] In this experiment, Sprague-Dawley rats weighing about 25Og were used as a control group (n=8, a no-administration group) and a test group (n=8, a group administered with the lacquer tree flavonoids
Results
title compound administration at 100 mg/kg dose caused a 2.5 fold or more increase in testosterone level; figure is given
Citation
LIFETREE BIOTECH CO., LTD.
Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Toxic : Subchronic
Assay Description
Effect : changes in organs and body weights Target : F344/DuCrj rat Bioassay : control to untreated rats 5 weeks age rats in 5 groups (10 rats of each sex) receive title comp. in diet for 13 weeks; rats observed daily for clinical signs and mortality; body weight and food consumption measured weekly; after 13 week rats sacrificed; organ weights measured
Results
reduction of body weights in male and female (5 percent groups): 16 and 14 percent, resp.; no changes in food consumptions; increase in relative liver and spleen weights in both sexes with 1.7 percent and 5 percent title comp. treatment, respectively;
Citation
Niho; Shibutani; Tamura; Toyoda; Uneyama; Takahashi; Hirose
Food and Chemical Toxicology, 2001 , vol. 39, # 11 p. 1063 - 1070 Title/Abstract Full Text View citing articles Show Details
Effect
Toxic : Subchronic
Assay Description
Effect : changes in parameters of hematology and blood biochemistry Target : F344/DuCrj rat Bioassay : Hb: hemoglobin; Ht: hematocrit; RBC: red blood cells; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; BUN: blood urea nitrogen; CRN: creatinine; ALP: alkaline phosphatase; control to untreated rats 5 weeks age rats in 5 groups (10 rats of each sex) receive title comp. in diet for 13 weeks; after 13 week rats anesthetized, blood sampled from abdominal aorta for hematology and blood biochemistry
Results
in males decrease of Hb, Ht, RBC in 0.6 percent and of RBC, MCV, MCH at 5 percent; in females decrease of MCV, MCH, RBC, Hb, Ht at 5 percent; sign. increase of reticulocytes at 5 percent; increase of BUN, ALP (only males) at 5 percent; decrease of CRN
Citation
Niho; Shibutani; Tamura; Toyoda; Uneyama; Takahashi; Hirose
Food and Chemical Toxicology, 2001 , vol. 39, # 11 p. 1063 - 1070 Title/Abstract Full Text View citing articles Show Details
Effect
Toxic : Subchronic
Assay Description
Effect : changes in parameters of histopathology Target : F344/DuCrj rat Bioassay : control to untreated rats 5 weeks age rats in 5 groups (10 rats of each sex) receive title comp. in diet for 13 weeks; after 13 week rats sacrificed and organs fixed in 10 percent formalin; tissue sections prepared and stained with hematoxilin and eosin in control and 5 percent treated groups
Results
dose-dependent centrilobular liver cell hypertrophy from 1.7 percent; increased incidences of extramedullary hematopoiesis in spleens and deposition of fine-grandular brown pigment in proximal tubular cells in rats of both sexes admin. 5 percent title
Citation
Niho; Shibutani; Tamura; Toyoda; Uneyama; Takahashi; Hirose
Food and Chemical Toxicology, 2001 , vol. 39, # 11 p. 1063 - 1070 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : |metabolic Bioassay : control: hot water instead of black tea intake in vivo; 10 healthy nonsmokers (8 males and 2 females, mean: 61.8 yrs and 28.0 kg/m2); 24-h urine samples collected during last week of 4-week test period; phenolic compounds in samples assessed by GC/MS
Results
only 3 metabolites were present at higher conc. in urine of all 10 subjects during tea-drinking in comparison to water drinking periods
Citation
Hodgson, Jonathan M.; Morton, Lincoln W.; Puddey, Ian B.; Beilin, Lawrence J.; Croft, Kevin D.
Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 6 p. 2276 - 2280 Title/Abstract Full Text View citing articles Show Details
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Biological material
Rattus norvegicus
Assay Description
Effect : |pharmacokinetics Bioassay : gastrointestinal absorption evaluated; 3 rats (6 wks, 170-205 g) fasted for 20 h; blood samples taken at each time point after dosing; serum levels determined by HPLC
Results
Cmax: 0.71 μmol/l; tmax: 60 min; AUC0-1.5 h: 42.6 μmol*min/l; serum conc.-time profiles
Citation
Konishi, Yutaka; Hitomi, Yoshitaka; Yoshioka, Eiji
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 9 p. 2527 - 2532 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : |biotransformation Bioassay : title comp. and its metabolite levels measured by HPLC ex vivo; metabolic fate of title comp. assayed; 6-week-old rats; food and water ad libitum; rats kept at 23 deg C under 12 h light/dark cycle; rats killed; liver removed and homogenized
Results
4-O-methyl gallic acid was detected in liver as metabolite but no title comp.
Citation
Zong, Li; Inoue, Makoto; Nose, Mitsuhiko; Kojima, Keisuke; Sakaguchi, Nahoko; Isuzugawa, Kazuto; Takeda, Tadahiro; Ogihara, Yukio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 3 p. 326 - 329 Title/Abstract Full Text View citing articles Show Details
Biological material
Rattus norvegicus
Assay Description
Effect : |biotransformation Bioassay : urine samples taken at determined times; title comp. and its metabolite levels measured by HPLC; VCI: inferior vena cava in vivo; metabolic fate of title comp. assayed; 6-week-old rats; food and water ad libitum; rats kept at 23 deg C under 12 h light/dark cycle; blood samples from portal vein and VCI collected at determined times
Results
title comp. existed in blood for ca. 6 h and more than half was metabolized to 4-O-methyl gallic acid followed by excretion into urine (metabolism rate 55.3 - 76.5 percent); graphical representation
Citation
Zong, Li; Inoue, Makoto; Nose, Mitsuhiko; Kojima, Keisuke; Sakaguchi, Nahoko; Isuzugawa, Kazuto; Takeda, Tadahiro; Ogihara, Yukio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 3 p. 326 - 329 Title/Abstract Full Text View citing articles Show Details
Effect
Anti-Metabolic disorder
Biological material
C57BL 6 mouse
Citation
Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou
Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details
Effect
Antidiabetic
Biological material
Wistar rat
Citation
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Effect
Antidiabetic
Biological material
Wistar rat
Citation
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
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Effect
Antidiabetic
Biological material
Wistar rat
Citation
Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah
European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details
Biological material
chicken
Citation
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Effect
Antineurodegenerative
Biological material
albino rat
Citation
Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.
Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details
Metabolism (50) Quantitative Results pX
Parameter
1
Foldincrease
Value (qual)
Value (quant)
Unit
Action on Target
NA
Inhibitor
Target
Tissue/Organ
Cell
Multidrug resistance protein 1 [human]:Wild
KB-C2 cell line
Cell fraction
Substrate /Carried Molecule [Rhodamine 123]+ (+)-Daunorubicin Hydrochloride
Dose
Reference (expand all/collapse all)
100 µM
Biochemical Pharmacology...
Title/Abstract Full Text View citing articles Show Details
Kitagawa, Shuji; Nabekura, Tomohiro; Kamiyama, Shizu; Takahashi, Tomoharu; Nakamura, Yutaka; Kashiwada, Yoshiki; Ikeshiro, Yasumasa
Biochemical Pharmacology, 2005 , vol. 70, # 8 p. 1262 - 1266 Title/Abstract Full Text View citing articles Show Details
% Inhibition
<
50
%
Inhibitor
Multidrug resistanceassociated protein 1 [human]:Wild
blood
erythrocyte
2',7'-bis-(3carboxypropyl)-5,6carboxyfluorescein acetoxymethyl ester
0 µM
Oncology Research, 2002 ...
Title/Abstract Full Text View citing articles Show Details
Bobrowska-Haegerstrand, Malgorzata; Wrobel, Anna; Mrowczynska, Lucyna; Soederstroem, Thomas; Shirataki, Yoshiaki; Motohashi, Noboru; Molnar, Joseph; Michalak, Krystyna; Haegerstrand, Henry
Oncology Research, 2002 , vol. 13, # 11 p. 463 - 469 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
Cytochrome P450 1A2 [human]:Wild
Baculovirusinfected insect cell
Microsome
7-Ethoxy-3cyanocoumarin
Xenobiotica, 2012 , vol...
Title/Abstract Full Text View citing articles Show Details
Yang, Li-Ping; Zhou, Zhi-Wei; Chen, Xiao-Wu; Li, Chun Guang; Sneed, Kevin B.; Liang, Jun; Zhou, Shu-Feng
Xenobiotica, 2012 , vol. 42, # 3 p. 238 - 255 Title/Abstract Full Text View citing articles Show Details
1
Foldincrease
NA
Inhibitor
Multidrug resistance protein 1 [human]:Wild
Chieli, Elisabetta; Romiti, Nadia; Rodeiro, Idania; Garrido, Gabino
Food and Chemical Toxicology, 2009 , vol. 47, # 11 p. 2703 - 2710 Title/Abstract Full Text View citing articles Show Details
HK-2
[Rhodamine 123]
0.500000 µM
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
2.63
% Inhibition
<
30
%
Arylamine Nacetyltransferase 1 [human]:Wild
KMBC cell line
Cytosol
p-Aminobenzoic acid
1000 µM
Xenobiotica, 2006 , vol...
Title/Abstract Full Text View citing articles Show Details
Kukongviriyapan; Phromsopha; Tassaneeyakul; Sripa; Hahnvajanawong; Bhudhisawasdi
Xenobiotica, 2006 , vol. 36, # 1 p. 15 - 28 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
NA
Arylamine Nacetyltransferase 1 [human]:Wild
liver
Cytosol
p-Aminobenzoic acid
1000 µM
Xenobiotica, 2006 , vol...
Title/Abstract Full Text View citing articles Show Details
Kukongviriyapan; Phromsopha; Tassaneeyakul; Sripa; Hahnvajanawong; Bhudhisawasdi
Xenobiotica, 2006 , vol. 36, # 1 p. 15 - 28 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
NA
Arylamine Nacetyltransferase 2 [human]:Wild
liver
Cytosol
Sulphadimidine
1000 µM
Xenobiotica, 2006 , vol...
Title/Abstract Full Text View citing articles Show Details
Kukongviriyapan; Phromsopha; Tassaneeyakul; Sripa; Hahnvajanawong; Bhudhisawasdi
Xenobiotica, 2006 , vol. 36, # 1 p. 15 - 28 Title/Abstract Full Text View citing articles Show Details
1
Foldincrease
NA
Caco-2
[3H]-Ochratoxin A
50 µM
Toxicology Letters, 2005...
Title/Abstract Full Text View citing articles Show Details
Sergent, Therese; Garsou, Serge; Schaut, Annelore; De Saeger, Sarah; Pussemier, Luc; Van Peteghem, Carlos; Larondelle, Yvan; Schneider, Yves-Jacques
Toxicology Letters, 2005 , vol. 159, # 1 p. 60 - 70 Title/Abstract Full Text View citing articles Show Details
4.15
Ki
=
70
µM
Inhibitor
Cytochrome P450 3A4:Wild
Current drug metabolism,...
Title/Abstract Full Text Show Details
Cytochrome P450 1A2 [Rattus norvegicus]:Wild
Current Drug Metabolism,...
Title/Abstract Full Text View citing articles Show Details
Cytochrome P450 3A1 [human]:Wild
Cytochrome P450 3A4 [human]:Wild
liver
Cytochrome P450 3A4:Wild
Murray, Michael
Current drug metabolism, 2006 , vol. 7, # 1 p. 67 - 81 Title/Abstract Full Text Show Details
Activity
=
1
mM
Inhibitor
Ow, Yin-Yin; Stupans, Ieva
Current Drug Metabolism, 2003 , vol. 4, # 3 p. 241 - 248 Title/Abstract Full Text View citing articles Show Details
4.15
Ki
=
70
µM
Radioligand (/ligand)
Current Drug Metabolism,...
Title/Abstract Full Text View citing articles Show Details
Ow, Yin-Yin; Stupans, Ieva
Current Drug Metabolism, 2003 , vol. 4, # 3 p. 241 - 248 Title/Abstract Full Text View citing articles Show Details
3.21
IC50
615.2
μM
Inhibitor
Microsome
testosterone
14 2939 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
3.17
IC50
669.5
μM
Inhibitor
testosterone
14 2939 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
4.3
IC50
50.3
μM
Inhibitor
Cytochrome P450 3A4:Wild
testosterone
14 2939 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
3.13
IC50
738
μM
Inhibitor
Cytochrome P450 3A4:Wild
testosterone
14 2939 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
4.23
IC50
59.2
μM
Inhibitor
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
testosterone
14 2939 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
testosterone
14 2939 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
3.14
IC50
722.8
μM
Inhibitor
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Inhibitor
Cytochrome P450 3A4:Wild
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Moderate
Inhibitor
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Inhibitor
Cytochrome P450 3A4:Wild
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
pX
Parameter % Inhibition
Value (qual) Moderate
Value (quant)
Unit
Action on Target Inhibitor
Target
Tissue/Organ
Cell
Cell fraction
Cytochrome P450 3A4:Wild
Substrate /Carried Molecule
Dose
Reference (expand all/collapse all)
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
% Inhibition
High
Inhibitor
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
% Inhibition
High
Inhibitor
Cytochrome P450 3A4:Wild
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
% Inhibition
High
Inhibitor
Cytochrome P450 3A4:Wild
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
% Inhibition
High
Inhibitor
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
% Inhibition
High
Inhibitor
Cytochrome P450 3A4:Wild
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
Inhibitor
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Low
Inhibitor
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
% Inhibition
Moderate
Inhibitor
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
testosterone
588 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
KI
485
μM
Inactivator
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
testosterone
01764 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
01764 μM
Xenobiotica, 2015 , vol...
Title/Abstract Full Text View citing articles Show Details
85 μM
Patent: US2016/184298 ...
Title/Abstract Full Text Show Details
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
kinact
0.05
min1
Inactivator
Cytochrome P450 3A4 [human]:Wild
liver
Microsome
testosterone
Pu, Qiang-Hong; Shi, Liang; Yu, Chao
Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
8.051
%
Inhibitor
UDPglucuronyltransferase 2B [Sprague Dawley rat]:Wild
liver
Microsome
NATIONAL DEFENSE MEDICAL CENTER; OLIVER, YOA-PU HU; HSIONG, CHENG-HUEI; WANG, MEI-TING; PAO, LI-HENG
Patent: US2016/184298 A1, 2016 ;
nalbuphine
Title/Abstract Full Text Show Details
1
% Inhibition
12.233
%
Inhibitor
UDPglucuronyltransferase 2B [Sprague Dawley rat]:Wild
liver
Microsome
nalbuphine
850 μM
Patent: US2016/184298 ...
Title/Abstract Full Text Show Details
nalbuphine
8.5 μM
Patent: US2016/184298 ...
Title/Abstract Full Text Show Details
30 μg/ml
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
NATIONAL DEFENSE MEDICAL CENTER; OLIVER, YOA-PU HU; HSIONG, CHENG-HUEI; WANG, MEI-TING; PAO, LI-HENG
Patent: US2016/184298 A1, 2016 ; Title/Abstract Full Text Show Details
1
% Inhibition
15.842
%
Inhibitor
UDPglucuronyltransferase 2B [Sprague Dawley rat]:Wild
liver
Microsome
NATIONAL DEFENSE MEDICAL CENTER; OLIVER, YOA-PU HU; HSIONG, CHENG-HUEI; WANG, MEI-TING; PAO, LI-HENG
Patent: US2016/184298 A1, 2016 ; Title/Abstract Full Text Show Details
3.75
Amount increase
Active
peritoneum macrophage
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
4.05
Amount increase
Active
peritoneum macrophage
15 60 μg/ml
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
3.75
Amount increase
Active
peritoneum macrophage
30 μg/ml
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
3.45
Amount increase
Active
peritoneum macrophage
60 μg/ml
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
3.83
% decrease
Active
25.0 μg/ml
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
3.53
% decrease
Active
50.0 μg/ml
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu
Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details
4.31
IC50
49
μM
liver
Microsome (pooled)
protocatechuic acid
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng
Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
Papp (transport)
1E-08
cm/s
Substrate
Multidrug resistance protein 4:Wild
MDCKMDR1 cell line
2 μM
ACS Chemical Neuroscienc...
Title/Abstract Full Text View citing articles Show Details
Deora, Girdhar Singh; Kantham, Srinivas; Chan, Stephen; Dighe, Satish N.; Veliyath, Suresh K.; McColl, Gawain; Parat, Marie-Odile; McGeary, Ross P.; Ross, Benjamin P.
ACS Chemical Neuroscience, 2017 , vol. 8, # 12 p. 2667 - 2675 Title/Abstract Full Text View citing articles Show Details
Transport ratio
29.3
no unit
Substrate
Multidrug resistance protein 4:Wild
MDCKMDR1 cell line
2 μM
ACS Chemical Neuroscienc...
Title/Abstract Full Text View citing articles Show Details
Deora, Girdhar Singh; Kantham, Srinivas; Chan, Stephen; Dighe, Satish N.; Veliyath, Suresh K.; McColl, Gawain; Parat, Marie-Odile; McGeary, Ross P.; Ross, Benjamin P.
ACS Chemical Neuroscience, 2017 , vol. 8, # 12 p. 2667 - 2675 Title/Abstract Full Text View citing articles Show Details
%
65
%
Substrate
Multidrug resistance protein 4:Wild
MDCKMDR1 cell line
2 μM
ACS Chemical Neuroscienc...
Title/Abstract Full Text View citing articles Show Details
Deora, Girdhar Singh; Kantham, Srinivas; Chan, Stephen; Dighe, Satish N.; Veliyath, Suresh K.; McColl, Gawain; Parat, Marie-Odile; McGeary, Ross P.; Ross, Benjamin P.
ACS Chemical Neuroscience, 2017 , vol. 8, # 12 p. 2667 - 2675 Title/Abstract Full Text View citing articles Show Details
Qualitative Information 1 of 6
2 of 6
3 of 6
Biological material
human HASMC cell line
Assay Description
Effect : cholesterol uptake; inhibition of Figure 11 is a graph showing the effect of active compounds from EO on uptake of cholesterol in human aortic smooth muscle cells. Confluent culture of cells grown in 96 well plates was incubated in serum- free medium with [3H] cholesterol (5 μCi/ml) with and without active fractions. After 24 h the
Results
title compound markedly inhibited cholesterol uptake in cells; figure is given
Citation
THE JOHNS HOPKINS UNIVERSITY; MERLION PHARMACEUTICAL PTC LTD
Patent: WO2008/80162 A2, 2008 ; Title/Abstract Full Text Show Details
Biological material
3T3-L1 cell line
Assay Description
Effect : glucose uptake differentiated cells tested; incubation time with title comp.: 30 min
Results
maximal percentage uptake 90 %
Citation
Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar
FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details
Effect
Anti-Atherogenis
Biological material
Mus musculus
Assay Description
Effect : Ox-LDL cellular uptake Bioassay : J774 A.1 macrophage Ox-LDL: oxidized low-density lipoprotein
Results
Ox-LDL cellular uptake reduction 44 %
Citation
Aviram, Michael; Volkova, Nina; Dreher, Mark; Rosenblat, Mira; Coleman, Raymond; Reddy, Muntha Kesava; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 3 p. 1148 - 1157 Title/Abstract Full Text View citing articles Show Details
4 of 6
5 of 6
6 of 6
Biological material
human Caco-2
Assay Description
Effect : |transport Bioassay : HBSS: Hank's balanced salt solution monolayer cells cultured; title comp. solution pH 6.0 or 7.4 added to apical side, HBSS pH 7.4 added to basolateral side; well incubated at 37 deg C; distribution of title comp. measured by HPLC
Results
title comp. transport in apical-basolateral direction was independent of pH and linearly increased with increasing concentration of title comp.; transport presumably via paracellular pathway
Citation
Konishi, Yutaka; Kobayashi, Shoko; Shimizu, Makoto
Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 11 p. 2317 - 2324 Title/Abstract Full Text View citing articles Show Details
Assay Description
Partition Coefficient of the compound was determined
Citation
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
Assay Description
Partition Coefficient of the compound was determined
Citation
Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details
Pharmacokinetic (8) Quantitative Results pX
Parameter
Value (qual)
Value (quant)
Unit
Biological Species
Route of administration
Dose
Dosing regimen
Population
Reference (expand all/collapse all)
Cmax
~
1.8
µM
human
Current Drug Metabolism,...
Title/Abstract Full Text View citing articles Show Details
Ow, Yin-Yin; Stupans, Ieva
Current Drug Metabolism, 2003 , vol. 4, # 3 p. 241 - 248 Title/Abstract Full Text View citing articles Show Details
t1/2
1.88
h
Wistar rat
oral administration
15 mg/kg
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng
Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
Tmax
1.17
h
Wistar rat
oral administration
15 mg/kg
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng
Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
Cmax
844.97
ng/ml
Wistar rat
oral administration
15 mg/kg
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng
Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
AUC
2402.35
ng/h/ml
Wistar rat
oral administration
15 mg/kg
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng
Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
MRT
3.08
h
Wistar rat
oral administration
15 mg/kg
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng
Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
Vc/F
16.97
l/kg
Wistar rat
oral administration
15 mg/kg
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng
Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
Clc/F
5.91
l/h/kg
Wistar rat
oral administration
15 mg/kg
Journal of Pharmaceutica...
Title/Abstract Full Text View citing articles Show Details
Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng
Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details
Toxicity/Safety Pharmacology (472) Quantitative Results pX
Parameter
Value (qual)
Value (quant)
Unit
Action on Target
Target
Tissue/Organ
Cell
Bioassay
Dose
Effect
Reference (expand all/collapse all)
3.35
CC50
0.45
mM
Cell/tumor cell: proliferation/viability/growth
Antineoplastic
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Ito, Hideyuki; Kobayashi, Eri; Takamatsu, Yoshie; Li, Shu-Hua; Hatano, Tsutomu; Sakagami, Hiroshi; Kusama, Kaoru; Satoh, Kazue; Sugita, Daigo; Shimura, Susumu; Itoh, Yoshio; Yoshida, Takashi
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 5 p. 687 - 693 Title/Abstract Full Text View citing articles Show Details
3.33
CC50
0.47
mM
Cell/tumor cell: proliferation/viability/growth
Antineoplastic
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Ito, Hideyuki; Kobayashi, Eri; Takamatsu, Yoshie; Li, Shu-Hua; Hatano, Tsutomu; Sakagami, Hiroshi; Kusama, Kaoru; Satoh, Kazue; Sugita, Daigo; Shimura, Susumu; Itoh, Yoshio; Yoshida, Takashi
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 5 p. 687 - 693 Title/Abstract Full Text View citing articles Show Details
3.28
CC50
0.53
mM
fibroblast
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Chemical and Pharmaceuti...
Title/Abstract Full Text View citing articles Show Details
Ito, Hideyuki; Kobayashi, Eri; Takamatsu, Yoshie; Li, Shu-Hua; Hatano, Tsutomu; Sakagami, Hiroshi; Kusama, Kaoru; Satoh, Kazue; Sugita, Daigo; Shimura, Susumu; Itoh, Yoshio; Yoshida, Takashi
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 5 p. 687 - 693 Title/Abstract Full Text View citing articles Show Details
3.59
IC50
44
µg/mL
U-87 MG
Cell/tumor cell: proliferation/viability/growth
Antineoplastic
Fitoterapia, 2011 , vol...
Title/Abstract Full Text View citing articles Show Details
Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.
Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details
3.66
IC50
37
µg/mL
Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.
Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284
SK-MEL28 cell line
Cell/tumor cell: proliferation/viability/growth
Antineoplastic
Fitoterapia, 2011 , vol...
Title/Abstract Full Text View citing articles Show Details
Title/Abstract Full Text View citing articles Show Details
4.19
IC50
11
µg/mL
SK-OV-3 cell line
Cell/tumor cell: proliferation/viability/growth
Antineoplastic
Fitoterapia, 2011 , vol...
Title/Abstract Full Text View citing articles Show Details
Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.
Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details
3.85
IC50
24
µg/mL
ARPE-19 cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Fitoterapia, 2011 , vol...
Title/Abstract Full Text View citing articles Show Details
Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.
Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details
3.94
IC50
19.47
µg/mL
Cell/tumor cell: proliferation/viability/growth
<= 40 µg/mL
Antineoplastic
Molecules, 2010 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Chia, Yi-Chen; Rajbanshi, Ranjan; Calhoun, Colonya; Chiu, Robert H.
Molecules, 2010 , vol. 15, # 11 p. 8377 - 8389 Title/Abstract Full Text View citing articles Show Details
2.36
MBC
0.75
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.95
MIC
0.19
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.36
MBC
0.75
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.43
MBC
0.63
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.43
MBC
0.63
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.53
MBC
0.5
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.23
MBC
1
mg/mL
Cell/tumor cell:
Antibiotic
Molecules, 2011 , vol. ...
proliferation/viability/growth
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MBC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.36
MBC
0.75
mg/mL
Cell/tumor cell: proliferation/viability/growth
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MBC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MBC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.36
MBC
0.75
mg/mL
Cell/tumor cell: proliferation/viability/growth
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
pX
Parameter
Value (qual)
Value (quant)
Unit
1
MBC
>
3
mg/mL
Action on Target
Target
Tissue/Organ
Cell
Effect
Reference (expand all/collapse all)
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Bioassay
Dose
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MBC
>
3
mg/mL
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.36
MBC
0.75
mg/mL
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.43
MBC
0.63
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MBC
>
3
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MBC
>
3
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.36
MBC
0.75
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MBC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MBC
>
3
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
0.25
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MIC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MIC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
0.25
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MIC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
0.25
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.43
MIC
0.63
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MIC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.65
MIC
0.38
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.43
MIC
0.63
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
3
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
3
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
0.25
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270
Title/Abstract Full Text View citing articles Show Details
2.13
MIC
1.25
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
3
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
3
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.74
MIC
0.31
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
2.95
MIC
0.19
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
3
mg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2011 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.
Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details
3.44
MIC50
62.5
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko
Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details
3.44
MIC50
62.5
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko
Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details
4.39
MIC90
62.5
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko
Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details
4.39
MIC90
62.5
mg/L
Cell/tumor cell:
Antibiotic
Antimicrobial Agents and...
proliferation/viability/growth
Title/Abstract Full Text View citing articles Show Details
Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko
Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details
3.74
MIC
31.3 62.5
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko
Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details
3.74
MIC
31.3 62.5
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Antimicrobial Agents and...
Title/Abstract Full Text View citing articles Show Details
Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko
Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details
4.9
MEC
12.5
µM
MCF7
Cell/tumor cell: proliferation/viability/growth
6.30000 µM
Cytotoxic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Fernandes, Iva; Faria, Ana; Azevedo, Joana; Soares, Susana; Calhau, Conceiao; De Freitas, Victor; Mateus, Nuno
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3785 - 3792 Title/Abstract Full Text View citing articles Show Details
2.82
MIC50
256
mg/L
Cell/tumor cell: proliferation/viability/growth
0.500000 mg/L
Antibiotic
Planta Medica, 2008 , v...
Title/Abstract Full Text View citing articles Show Details
Lin, Rong-Dih; Chin, Yi-Ping; Hou, Wen-Chi; Lee, Mei-Hsien
Planta Medica, 2008 , vol. 74, # 8 p. 840 - 846 Title/Abstract Full Text View citing articles Show Details
3.78
MIC90
256
mg/L
Cell/tumor cell: proliferation/viability/growth
0.500000 mg/L
Antibiotic
Planta Medica, 2008 , v...
Title/Abstract Full Text View citing articles Show Details
Lin, Rong-Dih; Chin, Yi-Ping; Hou, Wen-Chi; Lee, Mei-Hsien
Planta Medica, 2008 , vol. 74, # 8 p. 840 - 846 Title/Abstract Full Text View citing articles Show Details
3.12
MIC
128 256
mg/L
Cell/tumor cell: proliferation/viability/growth
0.500000 mg/L
Antibiotic
Planta Medica, 2008 , v...
Title/Abstract Full Text View citing articles Show Details
Lin, Rong-Dih; Chin, Yi-Ping; Hou, Wen-Chi; Lee, Mei-Hsien
Planta Medica, 2008 , vol. 74, # 8 p. 840 - 846 Title/Abstract Full Text View citing articles Show Details
2.63
MIC
400
mg/L
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.93
MIC
200
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.33
MIC
800
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.93
MIC
200
mg/L
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Bioscience, biotechnolog...
Title/Abstract Full Text Show Details
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
3.53
MIC
50
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.63
MIC
400
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.63
MIC
400
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.93
MIC
200
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.93
MIC
200
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.63
MIC
400
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.93
MIC
200
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
3.23
MIC
100
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
3.23
MIC
100
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
2.93
MIC
200
mg/L
Yamamoto, Hiroyo; Ogawa, Tomohiko
Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details
ZI
7.75
mm
Cell/tumor cell: proliferation/viability/growth
1000 µg/mL
Antimicrobial
Medicinal Chemistry, 201...
Title/Abstract Full Text View citing articles Show Details
Saavedra, Maria J.; Borges, Anabela; Dias, Carla; Aires, Alfredo; Bennett, Richard N.; Rosa, Eduardo S.; Simoes, Manuel
Medicinal Chemistry, 2010 , vol. 6, # 3 p. 174 - 183 Title/Abstract Full Text View citing articles Show Details
ZI
9
mm
Cell/tumor cell: proliferation/viability/growth
1000 µg/mL
Antimicrobial
Medicinal Chemistry, 201...
Title/Abstract Full Text View citing articles Show Details
Saavedra, Maria J.; Borges, Anabela; Dias, Carla; Aires, Alfredo; Bennett, Richard N.; Rosa, Eduardo S.; Simoes, Manuel
Medicinal Chemistry, 2010 , vol. 6, # 3 p. 174 - 183 Title/Abstract Full Text View citing articles Show Details
ZI
8
mm
Cell/tumor cell: proliferation/viability/growth
1000 µg/mL
Antimicrobial
Medicinal Chemistry, 201...
Title/Abstract Full Text View citing articles Show Details
Saavedra, Maria J.; Borges, Anabela; Dias, Carla; Aires, Alfredo; Bennett, Richard N.; Rosa, Eduardo S.; Simoes, Manuel
Medicinal Chemistry, 2010 , vol. 6, # 3 p. 174 - 183 Title/Abstract Full Text View citing articles Show Details
ZI
10
mm
Cell/tumor cell: proliferation/viability/growth
1000 µg/mL
Antimicrobial
Medicinal Chemistry, 201...
Title/Abstract Full Text View citing articles Show Details
Saavedra, Maria J.; Borges, Anabela; Dias, Carla; Aires, Alfredo; Bennett, Richard N.; Rosa, Eduardo S.; Simoes, Manuel
Medicinal Chemistry, 2010 , vol. 6, # 3 p. 174 - 183 Title/Abstract Full Text View citing articles Show Details
5.11
IC50
7.75
µM
HL-60 cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Tian, Li-Wen; Xu, Min; Li, Yan; Li, Xing-Yao; Wang, Dong; Zhu, Hong-Tao; Yang, Chong-Ren; Zhang, Ying-Jun
Chemistry and Biodiversity, 2012 , vol. 9, # 1 p. 123 - 130 Title/Abstract Full Text View citing articles Show Details
5.23
EC50
1
mg/L
Cell/tumor cell: proliferation/viability/growth
0.600000 mg/L
Toxic
Water Research, 2000 , ...
Title/Abstract Full Text View citing articles Show Details
Nakai, Satoshi; Inoue, Yutaka; Hosomi, Masaaki; Murakami, Akihiko
Water Research, 2000 , vol. 34, # 11 p. 3026 - 3032 Title/Abstract Full Text View citing articles Show Details
1.73
MIC
3200
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi; Nihei, Atsuko
Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 5 p. 1072 - 1076 Title/Abstract Full Text View citing articles Show Details
EC50
43.5
µmol
SK-BR-3 cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
EC50
71.3
µmol
AZ-521 cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
EC50
>
100
µmol
A-549
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
EC50
19.3
µmol
HL-60 cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
4.16
IC50
68.7
µM
Caco-2
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Forester, Sarah C.; Waterhouse, Andrew L.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5320 - 5327 Title/Abstract Full Text View citing articles Show Details
2.63
MBC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
0.59
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MBC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
0.59
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MBC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
1.18
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MBC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
0.59
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MBC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
0.59
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MBC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
1.18
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MBC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
0.59
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MBC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MIC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422
Title/Abstract Full Text View citing articles Show Details
2.63
MFC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
1.18
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.93
MFC
1.18
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
0.59
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.53
MFC
2.95
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
1.18
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MFC
0.295
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
0.295
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MFC
0.295
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.63
MIC
0.236
µmol/mL
Cell/tumor cell:
Antifungal
Journal of Agricultural ...
proliferation/viability/growth
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.75
MFC
0.177
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.93
MIC
0.118
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.23
MFC
0.59
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
0.295
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.63
MFC
2.36
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
1.18
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.93
MFC
1.18
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
0.59
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.53
MFC
2.95
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
1.18
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MFC
0.295
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MFC
0.295
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.63
MFC
0.236
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
0.295
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.53
MIC
0.295
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
3.75
MIC
0.177
µmol/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details
4.34
% Inhibition
39.9
%
Cell/tumor cell: proliferation/viability/growth
30 µM
Antineoplastic
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Zhang, Weihe; Liu, Yi; Chen, Xiaozhuo; Bergmeier, Stephen C.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2191 - 2194 Title/Abstract Full Text View citing articles Show Details
1.73
MIC
3200
mg/L
Kubo, Isao; Xiao, Ping; Nihei, Ken-Ichi; Fujita, Ken-Ichi; Yamagiwa, Yoshiro; Kamikawa, Tadao
Journal of agricultural and food chemistry, 2002 , vol. 50, # 14 p. 3992 - 3998 Title/Abstract Full Text Show Details
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of agricultural ...
Title/Abstract Full Text Show Details
3.8
IC50
160
µM
BT-549 cell line
Cell/tumor cell: proliferation/viability/growth
Antineoplastic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Antineoplastic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Antineoplastic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Antineoplastic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Antineoplastic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Proliferative
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details
3.63
IC50
235
µM
HT-29
Cell/tumor cell: proliferation/viability/growth
Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details
4.15
IC50
70.5
µM
SK-MEL cell line
Cell/tumor cell: proliferation/viability/growth
Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details
3.48
IC50
332
µM
KB
Cell/tumor cell: proliferation/viability/growth
Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details
3.98
IC50
105
µM
SK-OV-3 cell line
Cell/tumor cell: proliferation/viability/growth
Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details
3.47
IC50
341
µM
Cell/tumor cell: proliferation/viability/growth
Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
500
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
500
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1000
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1000
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1000
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1000
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
250
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
250
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
250
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.23
MIC
1000
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.83
MIC
250
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
3.74
MIC
31.3 62.5
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
4.33
MIC
7.9 31.3
mg/L
Cell/tumor cell: proliferation/viability/growth
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
2.53
MIC
500
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
3.12
MIC
128
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Planta Medica, 2003 , v...
Title/Abstract Full Text View citing articles Show Details
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
3.12
MIC
128
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Planta Medica, 2003 , v...
Title/Abstract Full Text View citing articles Show Details
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
3.12
MIC
128
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Planta Medica, 2003 , v...
Title/Abstract Full Text View citing articles Show Details
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
3.12
MIC
128
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Planta Medica, 2003 , v...
Title/Abstract Full Text View citing articles Show Details
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
3.12
MIC
128
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Planta Medica, 2003 , v...
Title/Abstract Full Text View citing articles Show Details
Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi
Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Fitoterapia, 2009 , vol...
Title/Abstract Full Text View citing articles Show Details
Liu, Manjuan; Katerere, David R.; Gray, Alexander I.; Seidel, Veronique
Fitoterapia, 2009 , vol. 80, # 6 p. 369 - 373 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Fitoterapia, 2009 , vol...
Title/Abstract Full Text View citing articles Show Details
Liu, Manjuan; Katerere, David R.; Gray, Alexander I.; Seidel, Veronique
Fitoterapia, 2009 , vol. 80, # 6 p. 369 - 373 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Fitoterapia, 2009 , vol...
Title/Abstract Full Text View citing articles Show Details
Liu, Manjuan; Katerere, David R.; Gray, Alexander I.; Seidel, Veronique
Fitoterapia, 2009 , vol. 80, # 6 p. 369 - 373 Title/Abstract Full Text View citing articles Show Details
1
CC
>
500
µM
Hep G2
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Wolfe, Kelly L.; Rui, Hai Liu
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details
GP (%)
107
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
46
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
96
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
109
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
83
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
112
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
99
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
114
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
70
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349
Title/Abstract Full Text View citing articles Show Details
GP (%)
126
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
110
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
107
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
105
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
97
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
GP (%)
102
%
Cell/tumor cell: proliferation/viability/growth
Antimicrobial
Journal of Agricultural ...
Title/Abstract Full Text View citing articles Show Details
Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details
1.73
MIC
3200
mg/L
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Xiao, Ping; Fujita, Ken'ichi
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 113 - 116 Title/Abstract Full Text View citing articles Show Details
4.36
LC50
43.9 57.4
µM
K-562 cell line
Cell/tumor cell: proliferation/viability/growth
Antineoplastic
Molecules, 2008 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Mitsuhashi, Shinya; Saito, Akiko; Nakajima, Noriyuki; Shima, Hiroshi; Ubukata, Makoto
Molecules, 2008 , vol. 13, # 12 p. 2998 - 3006 Title/Abstract Full Text View citing articles Show Details
4.54
LC50
28.7 29.2
µM
HEK293T cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Molecules, 2008 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Mitsuhashi, Shinya; Saito, Akiko; Nakajima, Noriyuki; Shima, Hiroshi; Ubukata, Makoto
Molecules, 2008 , vol. 13, # 12 p. 2998 - 3006 Title/Abstract Full Text View citing articles Show Details
2.03
MIC
1600
mg/L
Cell/tumor cell:
3200
Antibiotic
Journal of Agricultural ...
proliferation/viability/growth
mg/L
Title/Abstract Full Text View citing articles Show Details
Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi
Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 23 p. 6692 - 6696 Title/Abstract Full Text View citing articles Show Details
3.23
IC50
587.8
µM
Cell/tumor cell: proliferation/viability/growth
50 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details
4.44
IC50
6.2
mg/L
Cell/tumor cell: proliferation/viability/growth
50 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details
4.53
IC50
29.4
µM
Cell/tumor cell: proliferation/viability/growth
50 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details
3.28
IC50
524.3
µM
keratinocyte
Cell/tumor cell: proliferation/viability/growth
50 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details
4.14
IC50
72.3
µM
HtTA-1 cell line
Cell/tumor cell: proliferation/viability/growth
50 mg/L
Cytotoxic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio
Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
200
mg/L
Cell/tumor cell: proliferation/viability/growth
0.100000 mg/L
Antibiotic
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Bae, Eun-Ah; Han, Myung Joo; Kim, Nam-Jae; Kim, Dong-Hyun
Biological and Pharmaceutical Bulletin, 1998 , vol. 21, # 9 p. 990 - 992 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
8
%
Hep G2
Cell/tumor cell: proliferation/viability/growth
1 µg/mL
Cytotoxic
Asian Journal of Chemist...
Title/Abstract Full Text View citing articles Show Details
Xiang, Zhao Bao; Mo, Hai Qing; Qu, Zhong Tang; Xu, Hong Mei; Jiang, Hum Zhong
Asian Journal of Chemistry, 2011 , vol. 23, # 8 p. 3759 - 3760 Title/Abstract Full Text View citing articles Show Details
1
LD50
>
1000
µM
Biological and pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo
Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details
4.52
LD50
=
30
µM
Biological and pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo
Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details
4.58
LC50
=
4.53
µg/mL
Cytotoxic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
El-Sayed Ali, Tarik
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 11 p. 4385 - 4392 Title/Abstract Full Text View citing articles Show Details
=
5000
mg/kg
Material Safety Data She...
Full Text Show Details
320
mg/kg
Material Safety Data She...
Full Text Show Details
5000
mg/kg
Material Safety Data She...
Full Text Show Details
THP-1 cell line
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Material Safety Data Sheet Full Text Show Details
LD50
=
Material Safety Data Sheet Full Text Show Details
LD50
=
Material Safety Data Sheet Full Text Show Details
Toxicity
ND
Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details
1
Toxicity
NA
Toxic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz
European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
2.93
MIC
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
3.23
MIC
100
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
MLC
>
200
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antifungal
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.
Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details
4.23
IC50
10
µg/mL
HeLa cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Antiplasmodic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Marčetic̈, Mirjana; Božic̈, Dragana; Milenkovic̈, Marina; Maleševic̈, Nevenka; Radulovic̈, Siniša; Kovačevic̈, Nada
Phytotherapy Research, 2013 , vol. 27, # 11 p. 1658 - 1663 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
10
µg/mL
erythrocyte
Cell/tumor cell: proliferation/viability/growth
Garcia-Alvarez; Moussa; Njomnang Soh; Nongonierma; Abdoulaye; Nicolau-Travers; Fabre; Wdzieczak-Bakala; Ahond; Poupat; Ikhiri; Benoit-Vical
Journal of Ethnopharmacology, 2013 , vol. 149, # 3 p. 676 - 684 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
50
µM
Cell/tumor cell: proliferation/viability/growth
Antifungal
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Cell/tumor cell: proliferation/viability/growth
Antifungal
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Cell/tumor cell: proliferation/viability/growth
Antifungal
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Ito, Shinsaku; Nakagawa, Yasutaka; Yazawa, Satoru; Sasaki, Yasuyuki; Yajima, Shunsuke
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1812 - 1814 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
50
µM
Ito, Shinsaku; Nakagawa, Yasutaka; Yazawa, Satoru; Sasaki, Yasuyuki; Yajima, Shunsuke
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1812 - 1814 Title/Abstract Full Text View citing articles Show Details
1
MIC
>
50
µM
Ito, Shinsaku; Nakagawa, Yasutaka; Yazawa, Satoru; Sasaki, Yasuyuki; Yajima, Shunsuke
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1812 - 1814 Title/Abstract Full Text View citing articles Show Details
pX
Parameter
Value (qual)
Value (quant)
Unit
1
MIC
>
50
µM
Action on Target
Target
Tissue/Organ
Cell
Effect
Reference (expand all/collapse all)
Cell/tumor cell: proliferation/viability/growth
Antifungal
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Molecules, 2013 , vol. ...
Title/Abstract Full Text View citing articles Show Details
Cell/tumor cell:
Cytotoxic
Journal of Medicinal Che...
Bioassay
Dose
Ito, Shinsaku; Nakagawa, Yasutaka; Yazawa, Satoru; Sasaki, Yasuyuki; Yajima, Shunsuke
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1812 - 1814 Title/Abstract Full Text View citing articles Show Details
3.41
MIC
66.67
µg/mL
Deng, Ke-Zhong; Xiong, Ying; Zhou, Bin; Guan, Yong-Mei; Luo, Yong-Ming
Molecules, 2013 , vol. 18, # 10 p. 11859 - 11865 Title/Abstract Full Text View citing articles Show Details
3.79
IC50
163.1
µM
TA3/Ha cell
line
proliferation/viability/growth
Title/Abstract Full Text View citing articles Show Details
Jara, José A.; Castro-Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello, Antonio; Kemmerling, Ulrike; Maya, Juan Diego; Ferreira, Jorge
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2440 - 2454 Title/Abstract Full Text View citing articles Show Details
3.8
IC50
160.2
µM
TA3-MTX-R cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Jara, José A.; Castro-Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello, Antonio; Kemmerling, Ulrike; Maya, Juan Diego; Ferreira, Jorge
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2440 - 2454 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
200
µM
CCRF-CEM cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Jara, José A.; Castro-Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello, Antonio; Kemmerling, Ulrike; Maya, Juan Diego; Ferreira, Jorge
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2440 - 2454 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
200
µM
MM3MG cell line
Cell/tumor cell: proliferation/viability/growth
Cytotoxic
Journal of Medicinal Che...
Title/Abstract Full Text View citing articles Show Details
Jara, José A.; Castro-Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello, Antonio; Kemmerling, Ulrike; Maya, Juan Diego; Ferreira, Jorge
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2440 - 2454 Title/Abstract Full Text View citing articles Show Details
%
93.4
%
B16 melanoma 4A5 cell line
Cell/tumor cell: proliferation/viability/growth
30 µM
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
%
95.8
%
B16 melanoma 4A5 cell line
Cell/tumor cell: proliferation/viability/growth
10 µM
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
%
61.6
%
B16 melanoma 4A5 cell line
Cell/tumor cell: proliferation/viability/growth
100 µM
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
4.86
IC50
13.9
µM
HL-60 cell line
Cell/tumor cell: proliferation/viability/growth
1.00000E06 M
Cytotoxic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
4.54
IC50
29.1
µM
AZ-521 cell line
Cell/tumor cell: proliferation/viability/growth
1.00000E06 M
Cytotoxic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
1
IC50
>
100
µM
A-549
Cell/tumor cell:
1.00000E-
Cytotoxic
Chemistry and Biodiversi...
proliferation/viability/growth
06 M
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
4.26
IC50
54.7
µM
SK-BR-3 cell line
Cell/tumor cell: proliferation/viability/growth
1.00000E06 M
Cytotoxic
Chemistry and Biodiversi...
Title/Abstract Full Text View citing articles Show Details
Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro
Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details
ZI
32.41
mm
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Asian Journal of Chemist...
Title/Abstract Full Text View citing articles Show Details
Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong
Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details
ZI
25.71
mm
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Asian Journal of Chemist...
Title/Abstract Full Text View citing articles Show Details
Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong
Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details
ZI
30.03
mm
Cell/tumor cell: proliferation/viability/growth
Antifungal
Asian Journal of Chemist...
Title/Abstract Full Text View citing articles Show Details
Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong
Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details
ZI
23.85
mm
Cell/tumor cell: proliferation/viability/growth
Antifungal
Asian Journal of Chemist...
Title/Abstract Full Text View citing articles Show Details
Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong
Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details
ZI
23.3
mm
Cell/tumor cell: proliferation/viability/growth
Antifungal
Asian Journal of Chemist...
Title/Abstract Full Text View citing articles Show Details
Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong
Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details
1
% Stimulation
15
%
HUVEC cell line
Cell/tumor cell: proliferation/viability/growth
50 µg/mL
Proliferative
RSC Advances, 2014 , vo...
Title/Abstract Full Text View citing articles Show Details
He, Yonghui; Wang, Juan; Yan, Wei; Huang, Nan
RSC Advances, 2014 , vol. 4, # 1 p. 212 - 221 Title/Abstract Full Text View citing articles Show Details
4.2
% Stimulation
32
%
HUVEC cell line
Cell/tumor cell: proliferation/viability/growth
5 µg/mL
Proliferative
RSC Advances, 2014 , vo...
Title/Abstract Full Text View citing articles Show Details
He, Yonghui; Wang, Juan; Yan, Wei; Huang, Nan
RSC Advances, 2014 , vol. 4, # 1 p. 212 - 221 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
3
%
HUASMC cell line
Cell/tumor cell: proliferation/viability/growth
5 µg/mL
Antiproliferative
RSC Advances, 2014 , vo...
Title/Abstract Full Text View citing articles Show Details
He, Yonghui; Wang, Juan; Yan, Wei; Huang, Nan
RSC Advances, 2014 , vol. 4, # 1 p. 212 - 221 Title/Abstract Full Text View citing articles Show Details
3.67
% Inhibition
58
%
HUASMC cell line
Cell/tumor cell: proliferation/viability/growth
50 µg/mL
Antiproliferative
RSC Advances, 2014 , vo...
Title/Abstract Full Text View citing articles Show Details
He, Yonghui; Wang, Juan; Yan, Wei; Huang, Nan
RSC Advances, 2014 , vol. 4, # 1 p. 212 - 221 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
10.8
%
liver cell
Cell/tumor cell: proliferation/viability/growth
3 µM
Cytotoxic
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
14.2
%
liver cell
Cell/tumor cell: proliferation/viability/growth
10 µM
Cytotoxic
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
4.07
% Inhibition
26
%
liver cell
Cell/tumor cell: proliferation/viability/growth
30 µM
Cytotoxic
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
3.75
% Inhibition
35.9
%
liver cell
Cell/tumor cell: proliferation/viability/growth
100 µM
Cytotoxic
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
8.5
%
L929
Cell/tumor cell: proliferation/viability/growth
100 µM
Cytotoxic
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
2.8
%
L929
Cell/tumor cell: proliferation/viability/growth
30 µM
Cytotoxic
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
2.1
%
L929
Cell/tumor cell: proliferation/viability/growth
3 µM
Cytotoxic
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
0.2
%
L929
Cell/tumor cell: proliferation/viability/growth
10 µM
Cytotoxic
Phytochemistry, 2014 , ...
Title/Abstract Full Text View citing articles Show Details
Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details
5.03
% Inhibition
#
100
%
rHSC cell line
Cell/tumor cell: proliferation/viability/growth
30 µg/mL
Cytotoxic
Life Sciences, 2014 , v...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Shu-Chung; Wu, Chi-Hao; Wu, Chun-Chi; Yen, Jung-Hsing; Liu, Mei-Chun; Hsueh, Chi-Mei; Hsu, Shih-Lan
Life Sciences, 2014 , vol. 102, # 1 p. 55 - 64 Title/Abstract Full Text View citing articles Show Details
3.75
% Inhibition
>
50
%
rHSC cell line
Cell/tumor cell: proliferation/viability/growth
30 µg/mL
Cytotoxic
Life Sciences, 2014 , v...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Shu-Chung; Wu, Chi-Hao; Wu, Chun-Chi; Yen, Jung-Hsing; Liu, Mei-Chun; Hsueh, Chi-Mei; Hsu, Shih-Lan
Life Sciences, 2014 , vol. 102, # 1 p. 55 - 64 Title/Abstract Full Text View citing articles Show Details
4.8
IC50
15.7
μM
MCF7
5 - 20 μM
Cytotoxic
Bulletin of the Korean C...
Title/Abstract Full Text View citing articles Show Details
Kim, Tae-Woo; Paveen, Shehlar; Lee, Young Hun; Lee, Yong Sup
Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 4 p. 987 - 988 Title/Abstract Full Text View citing articles Show Details
4.79
IC50
16.1
μM
MCF7
5 - 20 μM
Cytotoxic
Bulletin of the Korean C...
Title/Abstract Full Text View citing articles Show Details
Kim, Tae-Woo; Paveen, Shehlar; Lee, Young Hun; Lee, Yong Sup
Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 4 p. 987 - 988 Title/Abstract Full Text View citing articles Show Details
4.8
IC50
15.8
μM
MDA-MB231
5 - 20 μM
Cytotoxic
Bulletin of the Korean C...
Title/Abstract Full Text View citing articles Show Details
Kim, Tae-Woo; Paveen, Shehlar; Lee, Young Hun; Lee, Yong Sup
Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 4 p. 987 - 988 Title/Abstract Full Text View citing articles Show Details
3.24
IC50
0.58
mM
HEK293 cell line
100 nM 1 mM
Cytotoxic
Patent: US2014/249095 ...
Title/Abstract Full Text Show Details
SH-SY5Y cell line
100 nM 1 mM
Cytotoxic
Patent: US2014/249095 ...
Title/Abstract Full Text Show Details
CCRF-CEM cell line
Cytotoxic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
National Normal University; LEE-CHEN, Guey-Jen; CHEN, Chiung-Mei
Patent: US2014/249095 A1, 2014 ; Title/Abstract Full Text Show Details
3.24
IC50
0.57
mM
National Normal University; LEE-CHEN, Guey-Jen; CHEN, Chiung-Mei
Patent: US2014/249095 A1, 2014 ; Title/Abstract Full Text Show Details
1
CC50
>
250
μM
Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana
European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
HepG 2
Cytotoxic
PLoS ONE, 2014 , vol. 9...
Title/Abstract Full Text View citing articles Show Details
Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan
PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
L6
Cytotoxic
PLoS ONE, 2014 , vol. 9...
Title/Abstract Full Text View citing articles Show Details
Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan
PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
3T3-L1 cell line
Cytotoxic
PLoS ONE, 2014 , vol. 9...
Title/Abstract Full Text View citing articles Show Details
Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan
PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
RIN-m2F cell line
Cytotoxic
PLoS ONE, 2014 , vol. 9...
Title/Abstract Full Text View citing articles Show Details
Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan
PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
MIN6
Cytotoxic
PLoS ONE, 2014 , vol. 9...
Title/Abstract Full Text View citing articles Show Details
Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan
PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
HT-29 cell line
1 - 100 μM
Antineoplastic
Journal of Pharmacology ...
Title/Abstract Full Text View citing articles Show Details
De Molina, Ana Ramírez; Vargas, Teodoro; Molina, Susana; Sánchez, Jenifer; Martínez-Romero, Jorge; González-Vallinas, Margarita; Martín-Hernández, Roberto; Sánchez-Martínez, Ruth; De Cedrón, Marta Gómez; Dávalos, Alberto; Calani, Luca; Del Rio, Daniele; González-Sarrías, Antonio; Espín, Juan Carlos; Tomás-Barberán, Francisco A.; Reglero, Guillermo
Journal of Pharmacology and Experimental Therapeutics, 2015 , vol. 353, # 2 p. 433 - 444 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
HUVEC cell line
50 μg/ml
Cytotoxic
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin
Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details
5.18
% Inhibition
>
90
%
THP-1 cell line
10 μg/ml
Cytotoxic
European Journal of Nutr...
Title/Abstract Full Text View citing articles Show Details
Del Bo, Cristian; Cao, Yi; Roursgaard, Martin; Riso, Patrizia; Porrini, Marisa; Loft, Steffen; Moller, Peter
European Journal of Nutrition, 2016 , vol. 55, # 1 p. 171 - 182 Title/Abstract Full Text View citing articles Show Details
5
% activity
50.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
21.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
4.6
% activity
28.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
4.78
% activity
37.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.47
% activity
74.5
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
16.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
4.54
% activity
25.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
46.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
14.8
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
11.4
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
15.4
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
13
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
16.2
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
13.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
4.66
% activity
31.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
4.61
% activity
29.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
15.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
9.8
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
15.9
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
12.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
24.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280
Title/Abstract Full Text View citing articles Show Details
1
% activity
20.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.55
% activity
78.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.61
% activity
80.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.77
% activity
85.4
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.98
% activity
90.5
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.61
% activity
80.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.9
% activity
88.8
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.58
% activity
79.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.83
% activity
87.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.27
% activity
65.2
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.39
% activity
70.9
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.45
% activity
74
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.63
% activity
81.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.42
% activity
72.5
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.52
% activity
76.9
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.35
% activity
69.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.48
% activity
75.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
4.89
% activity
43.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
4.99
% activity
49.7
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.42
% activity
72.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.53
% activity
77.2
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.4
% activity
71.3
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.52
% activity
76.8
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.12
% activity
56.8
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
5.25
% activity
64.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
0
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
14
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
10.9
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
11.2
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
8.5
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
12.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
10.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
14.7
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
11.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
25.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
21.2
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
12.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
13
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
12.8
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
11.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280
Title/Abstract Full Text View citing articles Show Details
Mortality rate
18.9
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
Mortality rate
15.8
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
22
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
19.7
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
14.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
9.5
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
19.7
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
11.2
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
20.1
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
12.6
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
20.8
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
1
% activity
18.2
%
10 μM
Phytotherapy Research, 2...
Title/Abstract Full Text View citing articles Show Details
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
4.23
% Inhibition
Active
WI-38 cell line
10 - 200 μg/ml
Cytotoxic
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Chaudhuri, Dipankar; Ghate, Nikhil Baban; Panja, Sourav; Das, Abhishek; Mandal, Nripendranath
PLoS ONE, 2015 , vol. 10, # 12 art. no. E0144280 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
rbl-2h3
10 - 100 μM
Cytotoxic
Journal of Natural Medic...
Title/Abstract Full Text View citing articles Show Details
Shi, Yan-Hong; Zhu, Shu; Tamura, Takayuki; Kadowaki, Makoto; Wang, Zhengtao; Yoshimatsu, Kayo; Komatsu, Katsuko
Journal of Natural Medicines, 2016 , vol. 70, # 2 p. 234 - 240 Title/Abstract Full Text View citing articles Show Details
4.23
% Inhibition
Active
HepG 2
10 μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.93
% Inhibition
Active
HepG 2
20μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.75
% Inhibition
Active
HepG 2
30μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.63
% Inhibition
Active
HepG 2
40μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.53
% Inhibition
Active
HepG 2
50 μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
4.23
% Inhibition
Active
MCF7
10 μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.93
% Inhibition
Active
MCF7
20μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.75
% Inhibition
Active
MCF7
30μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.63
% Inhibition
Active
MCF7
40μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.53
% Inhibition
Active
MCF7
50 μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
4.23
% Inhibition
Active
Caco-2 cell line
10 μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.93
% Inhibition
Active
Caco-2 cell line
20μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.63
% Inhibition
Active
Caco-2 cell line
40μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.53
% Inhibition
Active
Caco-2 cell line
50 μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.75
% Inhibition
Active
Caco-2 cell line
30μg/ml
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan
International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details
3.4
IC50
0.4
mM
A-549 cell line
0.01 - 30 mM
Cytotoxic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia
European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details
3.4
IC50
0.4
mM
A-549 cell line
0.01 - 30 mM
Cytotoxic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia
European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details
3.4
IC50
0.4
mM
A-549 cell line
0.01 - 30 mM
Cytotoxic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia
European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details
IC10
<
0.1
mM
BAEC cell line
0.01 - 20 mM
Cytotoxic
European Journal of Medi...
Title/Abstract Full Text View citing articles Show Details
Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia
European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details
5.25
IC50
0.96
μg/ml
T lymphocyte
3.125 50 μg/ml
Cytotoxic
Drug Design, Development...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng
Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details
% Viability
>
90
%
peripheral blood mononuclear cell
RAW 264.7 cell line
3.125 100 μg/ml
Cytotoxic
Drug Design, Development...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng
Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details
% Viability
>
90
%
3.125 100 μg/ml
Cytotoxic
Drug Design, Development...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng
Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details
3.67
IC50
36
μg/ml
MCF7
3.13 100 μg/ml
Cytotoxic
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Tor, Yin Sim; Yazan, Latifah Saiful; Foo, Jhi Biau; Wibowo, Agustono; Ismail, Norsharina; Cheah, Yoke Kqueen; Abdullah, Rasedee; Ismail, Maznah; Ismail, Intan Safinar; Yeap, Swee Keong
PLoS ONE, 2015 , vol. 10, # 6 art. no. E0127441 Title/Abstract Full Text View citing articles Show Details
3.69
IC50
35
μg/ml
MDA-MB231
3.13 100 μg/ml
Cytotoxic
PLoS ONE, 2015 , vol. 1...
Title/Abstract Full Text View citing articles Show Details
Tor, Yin Sim; Yazan, Latifah Saiful; Foo, Jhi Biau; Wibowo, Agustono; Ismail, Norsharina; Cheah, Yoke Kqueen; Abdullah, Rasedee; Ismail, Maznah; Ismail, Intan Safinar; Yeap, Swee Keong
PLoS ONE, 2015 , vol. 10, # 6 art. no. E0127441 Title/Abstract Full Text View citing articles Show Details
4.3
% viability
Active
RAW 264.7 cell line
50 μmol/l
Cytotoxic
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Li, Yi-jie; Xu, Cheng-ting; Lin, Dan-dan; Qin, Jiang-ke; Ye, Gao-jie; Deng, Qing-hua
Bioorganic and Medicinal Chemistry Letters, 2016 , vol. 26, # 15 p. 3425 - 3428 Title/Abstract Full Text View citing articles Show Details
4.3
% viability
Active
RAW 264.7 cell line
50 μmol/l
Cytotoxic
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Li, Yi-jie; Xu, Cheng-ting; Lin, Dan-dan; Qin, Jiang-ke; Ye, Gao-jie; Deng, Qing-hua
Bioorganic and Medicinal Chemistry Letters, 2016 , vol. 26, # 15 p. 3425 - 3428 Title/Abstract Full Text View citing articles Show Details
6
% decrease
Active
Caco-2 cell line
1 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
5
% decrease
Active
Caco-2 cell line
10 μM
Cytoprotective
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
11.1
%
Caco-2 cell line
10 μM
Antineoplastic
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
-0.2
%
Caco-2 cell line
0.1 μM
Antineoplastic
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
3.4
%
Caco-2 cell line
1 μM
Antineoplastic
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
% decrease
15.9
%
Caco-2 cell line
10 μM
Antineoplastic
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
% decrease
17.1
%
Caco-2 cell line
1 μM
Antineoplastic
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74
Title/Abstract Full Text View citing articles Show Details
% decrease
16.2
%
Caco-2 cell line
0.1 μM
Antineoplastic
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo
Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details
1
% decrease
Not active
Inhibitor
Tyrosinase:Wild
3T3 cell line
Cytotoxic
Patent: EP2467134 B1, ...
Title/Abstract Full Text Show Details
Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola
Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details
1
% decrease
Not active
Inhibitor
Tyrosinase:Wild
3T3 cell line
Phototoxic
Patent: EP2467134 B1, ...
Title/Abstract Full Text Show Details
Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola
Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details
4.96
CC50
11
μM
HepG 2
Cytotoxic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Aldulaimi, Omar; Uche, Fidelia I.; Hameed, Hamza; Mbye, Haddijatou; Ullah, Imran; Drijfhout, Falko; Claridge, Timothy D.W.; Horrocks, Paul; Li, Wen-Wu
Journal of Ethnopharmacology, 2017 , vol. 198, p. 221 - 225 Title/Abstract Full Text View citing articles Show Details
3.48
IC50
334.24
μM
HeLa cell line
50-400 μg/ml
Antineoplastic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Noreen, Hafiza; Farman, Muhammad; McCullagh, James S.O.
Journal of Ethnopharmacology, 2016 , vol. 194, p. 971 - 980 Title/Abstract Full Text View citing articles Show Details
4.23
IC50
58.41
μM
LN-18 cell line
50-400 μg/ml
Antineoplastic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Noreen, Hafiza; Farman, Muhammad; McCullagh, James S.O.
Journal of Ethnopharmacology, 2016 , vol. 194, p. 971 - 980 Title/Abstract Full Text View citing articles Show Details
2.63
IC50
2352.9
μM
HEK293T cell line
50-400 μg/ml
Cytotoxic
Journal of Ethnopharmaco...
Title/Abstract Full Text View citing articles Show Details
Noreen, Hafiza; Farman, Muhammad; McCullagh, James S.O.
Journal of Ethnopharmacology, 2016 , vol. 194, p. 971 - 980 Title/Abstract Full Text View citing articles Show Details
3.77
IC50
170
μM
A-375 cell line
10 nM 500 μM
Cytotoxic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details
3.82
IC50
150
μM
SK-MEL-28 cell line
10 nM 500 μM
Cytotoxic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details
3.7
IC50
200
μM
HeLa cell line
10 nM 500 μM
Cytotoxic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa
International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details
5
LC50
10 - 50
μM
MCF7
0.1 - 100 μM
Antineoplastic
Mechanisms of Ageing and...
Title/Abstract Full Text View citing articles Show Details
Atteya, Reham; Ashour, Mohamed E.; Ibrahim, Elsayed E.; Farag, Mohamed A.; El-Khamisy, Sherif F.
Mechanisms of Ageing and Development, 2017 , vol. 161, p. 141 - 148 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
<
15
%
MCF7
10 μM
Antineoplastic
Mechanisms of Ageing and...
Title/Abstract Full Text View citing articles Show Details
Atteya, Reham; Ashour, Mohamed E.; Ibrahim, Elsayed E.; Farag, Mohamed A.; El-Khamisy, Sherif F.
Mechanisms of Ageing and Development, 2017 , vol. 161, p. 141 - 148 Title/Abstract Full Text View citing articles Show Details
3.19
CC50
111.1
μg/ml
MDCK cell line
Cytotoxic
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Tran, Thu Thi; Kim, Meehyein; Jang, Yejin; Lee, Hye Won; Nguyen, Hoa Thi; Nguyen, Thanh Ngoc; Park, Hae Woong; Le Dang, Quang; Kim, Jin-Cheol
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 162 Title/Abstract Full Text View citing articles Show Details
% cell viability
80
%
ChaGo cell line
20 μg/ml
Antineoplastic
AAPS PharmSciTech, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Komenek, Seamkwan; Luesakul, Urarika; Ekgasit, Sanong; Vilaivan, Tirayut; Praphairaksit, Narong; Puthong, Songchan; Muangsin, Nongnuj
AAPS PharmSciTech, 2017 , vol. 18, # 4 p. 1104 - 1115 Title/Abstract Full Text View citing articles Show Details
5.25
IC50
0.96
μg/ml
peripheral lymphocyte
3.125 50 μg/ml
Antiproliferative
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
4.3
IC50
8.43
μg/ml
peripheral lymphocyte
3.125 50 μg/ml
Antiproliferative
BMC Complementary and Al...
Title/Abstract Full Text View citing articles Show Details
Yuandani; Jantan, Ibrahim; Husain, Khairana
BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details
% cell viability
100
%
RAW 264.7 cell line
100 μg/ml
Cytotoxic
Microbial Pathogenesis, ...
Title/Abstract Full Text View citing articles Show Details
Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk
Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
KB
<= 25 μM
Antineoplastic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
BT-549 cell line
<= 25 μM
Antineoplastic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732
Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
SK-OV-3 cell line
<= 25 μM
Antineoplastic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
VERO
<= 25 μM
Cytotoxic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
LLC PK1 cell line
<= 25 μM
Cytotoxic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
SK-MEL cell line
<= 25 μM
Antineoplastic
Natural Product Research...
Title/Abstract Full Text View citing articles Show Details
Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei
Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details
3.13
CC50
126.556
μg/ml
peritoneum macrophage
6.25 100 μg/ml
Cytotoxic
Naunyn-Schmiedeberg's Ar...
Title/Abstract Full Text View citing articles Show Details
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details
3.7
% Inhibition
>
50
%
1321N1 cell line
200 μM
Antineoplastic
Patent: WO2017/70052 A...
Title/Abstract Full Text Show Details
HepG 2
200 μM
Antineoplastic
Patent: WO2017/70052 A...
Title/Abstract Full Text Show Details
NPC-BM1
<= 50 μM
Antineoplastic
International Journal of...
Title/Abstract Full Text View citing articles Show Details
ONCO THERAPIES LLC; VASHISHTHA, Anshu; VASHISHTHA, Malini
Patent: WO2017/70052 A1, 2017 ; Title/Abstract Full Text Show Details
3.7
% Inhibition
>
50
%
ONCO THERAPIES LLC; VASHISHTHA, Anshu; VASHISHTHA, Malini
Patent: WO2017/70052 A1, 2017 ; Title/Abstract Full Text Show Details
1
% Inhibition
Not active
Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng
International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details
1
% Inhibition
Not active
RAW 264.7 cell line
Cytotoxic
Food and Chemical Toxico...
Title/Abstract Full Text View citing articles Show Details
Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.
Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details
% decrease
Low
MDA-MB231 cell line
5 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% decrease
Low
MDA-MB231 cell line
5 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% viability
34.7
%
HS 578T cell line
50 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% viability
37.6
%
MDA-MB231 cell line
50 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% viability
23.1
%
HS 578T cell line
50 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% viability
68.8
%
MCF-10F cell line
50 μmol/l
Cytotoxic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% decrease
Low
HS 578T cell line
5 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% decrease
Low
MCF-10F cell line
50 μmol/l
Cytotoxic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% decrease
Low
HS 578T cell line
5 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details
% viability
22.6
%
MDA-MB231 cell line
50 μmol/l
Antineoplastic
Anti-Cancer Drugs, 2017 ...
Title/Abstract Full Text View citing articles Show Details
Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih
Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156
Title/Abstract Full Text View citing articles Show Details
pX
Parameter
Value (qual)
% Inhibition
Value (quant)
Unit
0
%
Action on Target
Target
Tissue/Organ
Cell
Bioassay
Dose
Effect
Reference (expand all/collapse all)
Phytotoxic
Patent: WO2017/83490 A...
Title/Abstract Full Text Show Details
Phytotoxic
Patent: WO2017/83490 A...
Title/Abstract Full Text Show Details
STEPHEN F. AUSTIN STATE UNIVERSITY; LI, Shiyou; WANG, Ping; SU, Zushang
Patent: WO2017/83490 A1, 2017 ; Title/Abstract Full Text Show Details
% Inhibition
0
%
STEPHEN F. AUSTIN STATE UNIVERSITY; LI, Shiyou; WANG, Ping; SU, Zushang
Patent: WO2017/83490 A1, 2017 ; Title/Abstract Full Text Show Details
Qualitative Information 1 of 50
2 of 50
3 of 50
4 of 50
Target
enzyme:Wild
Assay Description
Effect : |enzyme; inhib. of Bioassay : DL-mevalonate prevents decrease of cell growth caused by inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase effect of title comp. on HMG-CoA reductase determined as cell growth with or without 1 mmol/l DL-mevalonate in Eagle's minimum essential medium at 37 deg C for 24 h by photometry (absorbance at 540 nm) after staining with methylrosaniline
Results
no growth observed
Citation
Chang, Jun-Jen; Chen, Tso-Hsiao; Chan, Paul; Chen, Yi-Jen; Hsu, Feng-Lin; Lo, Ming-Yu; Lin, Jung-Yaw
Pharmacology, 2001 , vol. 62, # 4 p. 224 - 228 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : Herpes simplex virus (HSV) infection; effect on Bioassay : with Herpes simplex virus (HSV) infection Example 7 External Treatment of HSV Infection in Clinical Tests Twenty-two patients who were clinically diagnosed with HSV infection were randomly selected and divided into two groups. Acyclovir ointment and micro emulsion containing propyl gallate prepared as described in Example 1 were applied to
Results
treatment with a microemulsion containing the title compound was more effective than treatment with acyclovir; treatment with title compound-containing microemulsion gave an average time for recovery of 3 days compared with average recovery time of 5.5
Citation
QIN, Weihua
Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details
Effect
Antibiotic
Biological material
Staphylococcus aureus
Assay Description
Effect : bacterial growth; inhibition of
Results
MBIC90 > 2000 μmol/l
Citation
BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS
Patent: US2012/88671 A1, 2012 ; Title/Abstract Full Text Show Details
Effect
Apoptotic
Assay Description
Target : human promyelocytic leukemia HL-60RG cells Bioassay : further investigations with antioxidant and radical scavengers; NAC: N-acetyl-L-cysteine, antioxidant; SOD: superoxide dismutase; BAPTA-AM: intracellular Ca(2+) chelator; reference comp.: 50
μmol/l H2O2 cells were treated with title comp. for 3 or 6 h: DNA fragmentation was analysed by agarose gel electrophoresis
5 of 50
Results
title comp. induced apoptosis; effect was prevented by catalase, NAC, ascorbic acid and BAPTA-AM and was not inhibited by SOD; H2O2-induced apoptosis was prevented only by NAC, BAPTA-AM and catalase
Citation
Inoue; Sakaguchi; Isuzugawa; Tani; Ogihara
Biological and Pharmaceutical Bulletin, 2000 , vol. 23, # 10 p. 1153 - 1157 Title/Abstract Full Text View citing articles Show Details
Effect
Hepatoprotective
Assay Description
6 of 50
7 of 50
8 of 50
9 of 50
Target : ddY mouse hepatocytes Bioassay : controls: untreated cells and cells from normal mice; D-GalN (D-galactosamine, 1.0 mmol/l) and TNF-α (tumor necrosis factor-α) induced cell death; ref.: silibinin (IC50: 33.6 μmol/l); MTT: 3(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide cells cultured in William's E medium; after 2-h incubation, medium replaced with fresh medium contg. D-GalN+title comp. at various concn.; 30 min later, TNF-α (100 ng/ml) added; cell viability assessed 18 h thereafter by MTT colorimetric reaction
Results
title comp. caused 8.3, 6.6 and 6.6 percent inhibition of D-GalN/TNF-α-induced cell death at conc. of 50, 100 and 200 μmol/l, resp.; table
Citation
Adnyana, I. Ketut; Tezuka, Yasuhiro; Banskota, Arjun Hari; Tran, Kim Qui; Kadota, Shigetoshi
Biological and Pharmaceutical Bulletin, 2000 , vol. 23, # 11 p. 1328 - 1332 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
Chlorocebus aethiops VERO
Assay Description
Effect : cytotoxic confluent cell monolayer tested
Results
MNCC maximal noncytotoxic concentration 0.59 mmol/l
Citation
Tian, Li-Wen; Zhang, Ying-Jun; Qu, Chang; Wang, Yi-Fei; Yang, Chong-Ren
Journal of Natural Products, 2010 , vol. 73, # 2 p. 160 - 163 Title/Abstract Full Text View citing articles Show Details
Effect
Cell Viability
Biological material
RAW 264.7 cell line
Assay Description
Effect : cell viability RAW 264.7: macrophage-like cell line; MTT assay; MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
Citation
Yang, Zhi-Gang; Jia, Liu-Nan; Shen, Yan; Ohmura, Atsuko; Kitanaka, Susumu
Molecules, 2011 , vol. 16, # 10 p. 8305 - 8318 Title/Abstract Full Text View citing articles Show Details
Effect
Neuroprotective
Biological material
PC12
Assay Description
Effect : H2O2-induced apotosis trypan blue exclusion method; PC12: rat pheochromocytoma cell line; cell viability rate decrease for control experiment: 52 percent
Results
cell viability rate decrease 19 percent
Citation
Crispo, James A.G.; Piche, Matthew; Ansell, Dominique R.; Eibl, Joseph K.; Tai, Isabella T.; Kumar, Aseem; Ross, Gregory M.; Tai
Biochemical and Biophysical Research Communications, 2010 , vol. 393, # 4 p. 773 - 778 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
10 of 50
11 of 50
12 of 50
13 of 50
Biological material
human SW480 cell line
Assay Description
Effect : cell viability MTT assay
Citation
Tian, Li-Wen; Xu, Min; Li, Yan; Li, Xing-Yao; Wang, Dong; Zhu, Hong-Tao; Yang, Chong-Ren; Zhang, Ying-Jun
Chemistry and Biodiversity, 2012 , vol. 9, # 1 p. 123 - 130 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human MCF7
Assay Description
Effect : cell viability MTT assay
Citation
Tian, Li-Wen; Xu, Min; Li, Yan; Li, Xing-Yao; Wang, Dong; Zhu, Hong-Tao; Yang, Chong-Ren; Zhang, Ying-Jun
Chemistry and Biodiversity, 2012 , vol. 9, # 1 p. 123 - 130 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human A-549
Assay Description
Effect : cell viability MTT assay
Citation
Tian, Li-Wen; Xu, Min; Li, Yan; Li, Xing-Yao; Wang, Dong; Zhu, Hong-Tao; Yang, Chong-Ren; Zhang, Ying-Jun
Chemistry and Biodiversity, 2012 , vol. 9, # 1 p. 123 - 130 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
human
Assay Description
Effect : cell viability Bioassay : normal kidney proximal tubule HK-2 cells neutral red assay; trypan-blue exclusion test; confluent culture tested
Citation
Chieli, Elisabetta; Romiti, Nadia; Rodeiro, Idania; Garrido, Gabino
Chemico-Biological Interactions, 2010 , vol. 186, # 3 p. 287 - 294 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
14 of 50
Target : human promyelocytic leukemia HL-60RG cells Bioassay : cells treated with title comp. for 6 h; fluorescence micrograph taken after staining with Hoechst 33258
Results
chromatin condensation and nuclear fragmentation was observed in cells treated with title comp.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
Target : human promyelocytic leukemia HL-60RG cells Bioassay : cells treated with title comp. for 6 h; subjected to morphological examination by light microscopy
15 of 50
Results
morphological examination revealed appearance of cell shrinkage and partial chromatin condensation
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
16 of 50
Results
internucleosomal DNA cleavage of 180-200 bp multiples was observed in cells treated with title comp.; effect was prevented by W-7, BAPTA-AM, ascorbic acid, NAC, catalase, SOD and ZnSO4; fig.
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
17 of 50
morphological examination revealed appearance of cell shrinkage and partial chromatin condensation
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Target : rat hepatoma dRLh-84 cells Bioassay : cells treated with title comp. for 6 h; terminal deoxyribonucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling assay performed to detect DNA fragmentation
Results
title comp. induced apoptosis with DNA cleavage into large fragments
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
19 of 50
Target : rat hepatoma dRLh-84 cells Bioassay : cells treated with title comp. for 6 h; subjected to morphological examination by light microscopy
Results
Assay Description
18 of 50
Target : human promyelocytic leukemia HL-60RG cells Bioassay : further study with calmodulin inhibitor W-7, intracellular Ca(2+) chelator BAPTA-AM, ascorbic acid, thiol oxidant N-acetyl-L-cysteine (NAC), catalase, superoxide dismutase (SOD), Ca(2+)/Mg(2+)-dependent endonuclease inhibitor ZnSO4 cells cultured in RPMI-1640 medium; treated with title comp. for 6 h; incubated for 10 min in lysis buffer at room temp.; centrifuged, 10 min at 4 deg C; DNA isolated; DNA fragmentation analysed by agarose gel electrophoresis (agarose gel 1.5%)
Target : rat hepatoma dRLh-84 cells Bioassay : cells cultured in MEM-Eagle's salts; treated with title comp. for 6 h; incubated for 10 min in lysis buffer at room temp.; centrifuged, 10 min at 4 deg C; DNA isolated; DNA fragmentation analysed by agarose gel electrophoresis (agarose gel 1.5%)
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
Target : rat hepatoma dRLh-84 cells Bioassay : cells treated with title comp. for 6 h; fluorescence micrograph taken after staining with Hoechst 33258
20 of 50
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human PLC/PRF/5 cell line
Assay Description
21 of 50
Results
morphological examination revealed appearance of cell shrinkage and partial chromatin condensation
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human PLC/PRF/5 cell line
Assay Description
22 of 50
title comp. induced apoptosis with DNA cleavage into large fragments
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human PLC/PRF/5 cell line
Bioassay : cells cultured in RPMI-1640 medium; treated with title comp. for 6 h; incubated for 10 min in lysis buffer at room temp.; centrifuged, 10 min at 4 deg C; DNA isolated; DNA fragmentation analysed by agarose gel electrophoresis (agarose gel 1.5%)
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human PLC/PRF/5 cell line
Assay Description
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Bioassay : cells treated with title comp. for 6 h; terminal deoxyribonucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling assay performed to detect DNA fragmentation
Results
Assay Description
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Bioassay : cells treated with title comp. for 6 h; subjected to morphological examination by light microscopy
Bioassay : cells treated with title comp. for 6 h; fluorescence micrograph taken after staining with Hoechst 33258
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human HtTA-1 cell line
Assay Description
Bioassay : cells treated with title comp. for 6 h; subjected to morphological examination by light microscopy
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Results
morphological examination revealed appearance of cell shrinkage and partial chromatin condensation
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human HtTA-1 cell line
Assay Description
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Results
title comp. induced apoptosis with DNA cleavage into large fragments
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human HtTA-1 cell line
Assay Description
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Bioassay : cells cultured in MEM-Eagle's salt; treated with title comp. for 6 h; incubated for 10 min in lysis buffer at room temp.; centrifuged, 10 min at 4 deg C; DNA isolated; DNA fragmentation analysed by agarose gel electrophoresis (agarose gel 1.5%)
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
human HtTA-1 cell line
Assay Description
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Bioassay : cells treated with title comp. for 6 h; terminal deoxyribonucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling assay performed to detect DNA fragmentation
Bioassay : cells treated with title comp. for 6 h; fluorescence micrograph taken after staining with Hoechst 33258
Citation
Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio
Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
murine cells
Assay Description
Effect : cytotoxic
Results
cell viability 85.7 percent
Citation
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
Mus musculus
Assay Description
Effect : cytotoxic
Bioassay : monocyte macrophage RAW264.7 cells 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide-based colorimetric assay
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Citation
Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej
Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
HL-60 cell line
Assay Description
Effect : cytotoxic Species : myelomonocytic HL-60 cells
Citation
Dobroslawa, Bialonska; Kasimsetty, Sashi G.; Khan, Shabana I.; Daneel, Ferreira
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 21 p. 10181 - 10186 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Biological material
Caco-2
Assay Description
Effect : enzyme activity 80% confluent culture tested; pNA: p-nitroaniline
Results
enzyme specific activity 1.9 pmol of pNA liberated/(h*μg of protein)
Citation
Forester, Sarah C.; Waterhouse, Andrew L.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5320 - 5327 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
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Target : mouse monocyte/macrophage RAW264.7 cells Bioassay : viability of cells determined spectrophotometrically using MTT assay; viability of cells activated only with LPS/IFN-γ was arbitrally set as 100, and other results were normalized to this control in vitro; effect of title comp. on viability of cells activated with LPS/IFN-γ assayed; cells incubated with title comp. in DMEM with 10 percent FBS at 37 deg C for 1 h before, and 24 h after stimulation with LPS/IFN-γ
Results
viability of cells ( percent) / dose (μmol/l): 110/16, 108/31, 108/63, 97/125, 108/250, 20/500
Citation
Wang, Jian; Mazza
Journal of agricultural and food chemistry, 2002 , vol. 50, # 15 p. 4183 - 4189 Title/Abstract Full Text Show Details
Effect
Apoptotic
Biological material
human NCI-H460 cell line
Assay Description
Effect : reactive oxygen species production
Citation
Bin-Chuan; Hsu, Wu-Huei; Yang, Jai-Sing; Hsia, Te-Chun; Lu, Chi-Cheng; Chiang, Jo-Hua; Yang, Jiun-Long; Lin, Ching-Hsiung; Jen-jyh; Lee-jen, Wu Suen; Wellington, Gibson Wood; Chung, Jing-Gung
Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 16 p. 7596 - 7604 Title/Abstract Full Text View citing articles Show Details
Effect
Proliferative
Biological material
human HT-29
Assay Description
Effect : clonogenic efficiency
ability of the compounds to decrease clonogenic efficiency was determined by their capability to decrease colony formation compared to vehicle (DMSO 0.1%) control
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Results
percent decrese 66 percent
Citation
Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details
Effect
Proliferative
Biological material
Chlorocebus aethiops
Assay Description
Effect : cell proliferation Bioassay : kidney fibroblasts number of viable cells determined using the neutral red assay procedure
Citation
Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details
Effect
Antiproliferative
Assay Description
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Results
cell viability was 91.0 percent and 69.1 percent at 20 and 100 μmol/l of title comp., respectively compared to control
Citation
Kwon, Ki Han; Murakami, Akira; Ohigashi, Hajime
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 2 p. 436 - 439 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Biological material
MCF7
Assay Description
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Bioassay : growth inhibition analysis; MTT = 3-<4,5-dimethylthiazol-2-yl>-2,5-diphenyltetrazolium bromide cell cultured in RPMI-1640 supplemented with 10 percent fetal calf serum; title comp. incubation (37 deg C, 48 h, 5 percent CO2 in air, high humidity); MTT staining; colorimetry at 570 nm
Citation
Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko
Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details
Effect
Cytoprotective
Assay Description
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Target : ICR mouse peritoneal exudate cells Bioassay : MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; control: without title comp.; DSS: dextran sulfate sodium test cells incubated with title comp. in Dulbecco's Modified Eagle Medium at 37 deg C for 30 min in 5 percent humidified CO2 atmosphere; 1 μg/ml DSS added and incubated for 12 h; cell viability measured with MTT test
Target : renal epithelial LLC-PK1 cells Bioassay : SIN-1: 3-morpholino-sydnonimine, 0.6 mmol/l; PG: pyrogallol, 0.6 mmol/l; SNP: sodium nitroprusside, 0.6 mmol/l; MTT: 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide; further studies on peroxynitrite formation cells incubated with title comp. and SIN-1 or PG or SNP for 24 h at 37 deg C, then MTT added for 4 h; absorbance read at 540 nm
Results
title comp. dose-dependently inhibited SIN-1-induced cell death, at 2.5 μg/ml cell viability: 93 percent
Citation
Yokozawa, Takako; Lee, Kyeoung Im; Nakagawa, Takako; Cho, Eun Ju; Chung, Hae Young
Pharmacy and Pharmacology Communications, 1999 , vol. 5, # 11 p. 657 - 661 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
Effect : growth Target : Escherichia coli IC188
Bioassay : parent WP2 uvrA/pKM101 bacterial strain in vitro; LA plates; paper discs impregnated with title comp. placed on solidified top agar; incubated overnight; diameter of inhibition zone determined
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Results
diameter of inhibition zone 3 mm
Citation
Martinez, A.; Urios, A.; Blanco, M.
Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details
Effect
Cytotoxic
Assay Description
Effect : growth Target : Escherichia coli IC203 Bioassay : WP2 uvrA/pKM101 bacterial strain deficient in OxyR in vitro; LA plates; paper discs impregnated with title comp. placed on solidified top agar; in the pres. and abs. of S9 mix; inhibition zone determined
Results
diameter of inhibition zone 3-18 mm; cytotoxicity of title comp. inhibited by S9
Citation
Martinez, A.; Urios, A.; Blanco, M.
Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details
Effect
Apoptotic
Assay Description
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Results
title comp. dose- and time-depend. induced DNA fragmentation in ladder-like pattern; effect decreased by catalase; fig.
Citation
Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng
Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details
Effect
Antiangiogenic
Biological material
zebra fish
Assay Description
Effect : intersegmental vessel growth Bioassay : embryo embryos at 24 hours post fertilization were used in assay
Citation
Zhao, Yan-Li; He, Qiu-Xia; Li, Yang; Wang, Si-Feng; Liu, Ke-Chun; Yang, Yong-Ping; Li, Xiao-Li
Molecules, 2010 , vol. 15, # 4 p. 2178 - 2186 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
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Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : further invest. with vitamin C, vitamin E and catalase cells incubated with title comp. for 2-6 h; apoptosis induction studied by analysis of DNA fragmentation using 1.5% agarose gel electrophoresis; ethidium bromide staining
Target : 3T3-L1 preadipocytes BCRC 60159 Bioassay : DMEM with 10 percent FBS; humidified 5 percent CO2; 37 deg C; incubated for 6, 12, and 24 h; mitochondrial membrane potential determined
Results
title comp. induced disruption of mitochondrial membrane potential (induced apoptosis)
Citation
Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
Target : 3T3-L1 preadipocytes BCRC 60159
Bioassay : DMEM with 10 percent FBS; humidified 5 percent CO2; 37 deg C; incubated for 72 h; flow cytometric analysis of annexin V-FITC/PI double stained cells
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Results
at 50/100/250 μmol/l title comp. induced 10.0/17.0/20.6, 1.4/1.2/2.1, and 0.0/0.1/0.1 percent of early apoptosis, late apoptosis, and necrosis, respectively
Citation
Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details
Effect
Neuroprotective
Assay Description
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Results
degree of cell survival was 59.7 percent of control level; table
Citation
Mook-Jung, Inhee; Kim, Hee; Fan, Wenzhe; Tezuka, Yasuhiro; Kadota, Shigetoshi; Nishijo, Hisao; Jung, Min Whan
Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 8 p. 1101 - 1104 Title/Abstract Full Text View citing articles Show Details
Effect
Apoptotic
Assay Description
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Target : rat brain B103 neuronal cells Bioassay : control: untreated cells; MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide; cell survival expressed as percent of control (100 percent cell survival); Aβ25-35 (beta-amyloid) induce cell death with reduced cell survival of 63.5 percent 5E3 cells/well in 96-well plates in DMEM treated with title comp.; 1 h later, Aβ25-35 (25 μmol/l) added; 18 h later, MTT added; incubated at 37 deg C, 4 h; degree of cell survival detd. based on absorbance at 570-630 nm using plate reader
Target : embryo 3T3-L1 pre-adipocytes BCRC 60159 Bioassay : also pre-treated with general caspase-9 inhibitor (Z-LEHD-FMK) and caspase-3 inhibitor (Z-DEVD-FMK); HDAC: histone deacetylase cultured with title comp. for 6, 12, and 48 h; cell morphology examined after PI or DAPI staining; expression of pro- and anti-apoptotic proteins determined by Western blot analysis; expression of Caspase-3 and -9 proteins and HDAC activity assessed
Results
title comp. induced apoptosis in pre-adipocytes through Fas and mitochondrial pathway (stimulated increase in protein expression of Fas, Fasl, and p53, changed ratio of expression levels of pro- and antiapoptotic Bcl-2 family members); fig.
Citation
Hsu, Chin-Lin; Lo, Wen-Hsieh; Yen, Gow-Chin
Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7359 - 7365 Title/Abstract Full Text View citing articles Show Details
Effect
Cell Viability
Assay Description
Effect : cell viability Bioassay : murine peritoneal macrophages
Citation
He, Rong-Rong; Yao, Xin-Sheng; Yao, Nan; Wang, Min; Dai, Yi; Gao, Hao; Yu, Yang; Kurihara, Hiroshi
Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 5 p. 1129 - 1136 Title/Abstract Full Text View citing articles Show Details
Effect
Cytotoxic
Assay Description
Effect : cytotoxic Bioassay : murine macrophage-like RAW 246.7 cells
Results
cell viability > 85 percent
Citation
Kolodziej, Herbert; Radtke, Oliver A.; Kiderlen, Albrecht F.
Phytochemistry, 2008 , vol. 69, # 18 p. 3103 - 3110 Title/Abstract Full Text View citing articles Show Details
Biological material
chicken
Citation
Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.
Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details
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Identification Physical Data Spectra Other Data
Effect
Hemolytic
Biological material
sheep erythrocyte
Citation
Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details