3,4,5-Trihydroxybenzoic acid (Gallic acid) [C7H6O5]

Page 1

Reaxys

PubChem

eMolecules

LabNetwork

Bioactivities (2811)

SigmaAldrich

Reactions (1573)

Substances (1)

Targets (176)

Structure

Citations (7114)

N° of preparations All Preps | All Reactions

Structure/Compound Data Chemical Name: 3,4,5-trihydroxybenzoic acid

274 prep out of 1573 reactions.

Reaxys Registry Number: 2050274

CAS Registry Number: 149-91-7 Type of Substance: isocyclic Molecular Formula: C7H6O5

Linear Structure Formula: C6H2(OH)3COOH Molecular Weight: 170.122 InChI Key: LNTHITQWFMADLM-UHFFFAOYSA-N

1

Available Data

Target

N° of ref.

Druglikeness

Bioactivity

Identification Physical Data (563) Spectra (428) Other Data (1122)

Show Targets

7114

Synthesize | Hide Details Find similar Chemical Names and Synonyms 3,4,5-trihydroxybenzoic acid, gallic acid, 3,4,5-Trihydroxybenzoic acid Druglikeness Bioactivity In vitro: Efficacy (1828) Quantitative Results pX

Parameter

4.4

IC50

Value (qual)

Value (quant)

Unit

40

µM

Action on Target

Target enzyme:Wild

Tissue/Organ

Cell

Bioassay In Vitro (others)

Dose

Effect

Reference (expand all/collapse all) Bioscience, biotechnolog...

Title/Abstract Full Text Show Details


Kato, Yoji; Nagao, Akihiko; Terao, Junji; Osawa, Toshihiko

Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 5 p. 1136 - 1139 Title/Abstract Full Text Show Details

5.03

IC50

1.6

µg/mL

In Vitro (others)

Antineoplastic

Fitoterapia, 2011 , vol...

Title/Abstract Full Text View citing articles Show Details

In Vitro (others)

Antineoplastic

Fitoterapia, 2011 , vol...

Title/Abstract Full Text View citing articles Show Details

In Vitro (others)

Antioxidant

Phytochemistry, 2010 , ...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

Phytochemistry, 2010 , ...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.

Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details

4.71

IC50

3.3

µg/mL

Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.

Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details

5.49

IC50

3.24

µM

Pfundstein, Beate; El Desouky, Samy K.; Hull, William E.; Haubner, Roswitha; Erben, Gerhard; Owen, Robert W.

Phytochemistry, 2010 , vol. 71, # 10 p. 1132 - 1148 Title/Abstract Full Text View citing articles Show Details

EC1

170

µM

In Vitro (others)

Pfundstein, Beate; El Desouky, Samy K.; Hull, William E.; Haubner, Roswitha; Erben, Gerhard; Owen, Robert W.

Phytochemistry, 2010 , vol. 71, # 10 p. 1132 - 1148 Title/Abstract Full Text View citing articles Show Details

4.96

EC50

1.85

µg/mL

In Vitro (others)

0.00500000 µg/mL

Mazimba, Ofentse; Majinda, Runner R.T.; Modibedi, Ceciliah; Masesane, Ishmael B.; Cencic, Avrelija; Chingwaru, Walter

Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 17 p. 5225 - 5230 Title/Abstract Full Text View citing articles Show Details

4.3

IC50

49.9

µM

Patent: US2010/137249 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Wang, Binghe; Ni, Nanting; Wang, Junfeng; Lu, Chung-Dar; Chou, Han-Ting; Li, Minyong; Zheng, Shilong; Cheng, Yunfeng; Peng, Hanjing

Patent: US2010/137249 A1, 2010 ; Title/Abstract Full Text Show Details

2.47

IC50

574.2

µg/mL

lipase:Wild

Enzymology inhibition

enzyme [carp]:Wild

In Vitro (others)

Patent: US2011/263698 ...

Title/Abstract Full Text Show Details

NICHIREI BIOSCIENCES, INC.

Patent: US2011/263698 A1, 2011 ; Title/Abstract Full Text Show Details

3.5

IC50

0.316

mM

0.100000 µM

Bulletin of Environmenta...

Title/Abstract Full Text View citing articles Show Details

Varanka; Szegletes; NemcsoI k; AI brahaI m

Bulletin of Environmental Contamination and Toxicology, 1999 , vol. 63, # 6 p. 751 - 758 Title/Abstract Full Text View citing articles Show Details

3.83

EC50

25

mg/L

In Vitro (others)

Antiparasitic

Planta Medica, 2001 , v...

Title/Abstract Full Text View citing articles Show Details

In Vitro

Antiparasitic

Planta Medica, 2001 , v...

Kolodziej; Kayser; Kiderlen; Ito; Hatano; Yoshida; Foo

Planta Medica, 2001 , vol. 67, # 9 p. 825 - 832 Title/Abstract Full Text View citing articles Show Details

4.59

EC50

4.4

mg/L


(others)

Title/Abstract Full Text View citing articles Show Details

Kolodziej; Kayser; Kiderlen; Ito; Hatano; Yoshida; Foo

Planta Medica, 2001 , vol. 67, # 9 p. 825 - 832 Title/Abstract Full Text View citing articles Show Details

4.04

EC50

15.6

mg/L

In Vitro (others)

Cytotoxic

Planta Medica, 2001 , v...

Title/Abstract Full Text View citing articles Show Details

Kolodziej; Kayser; Kiderlen; Ito; Hatano; Yoshida; Foo

Planta Medica, 2001 , vol. 67, # 9 p. 825 - 832 Title/Abstract Full Text View citing articles Show Details

5.3

IC50

5

µM

In Vitro (others)

0.0200000 µM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Maggi-Capeyron; Ceballos; Cristol; Delbosc; Le Doucen; Pons; Leger; Descomps

Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 11 p. 5646 - 5652 Title/Abstract Full Text View citing articles Show Details

5.17

EC50

6.83

µM

In Vitro (others)

Antioxidant

Journal of the Brazilian...

Title/Abstract Full Text View citing articles Show Details

Lianda, Regina L. P.; Sant'ana, Luiza D'Oliveira; Echevarria, Aurea; Castro, Rosane N.

Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 4 p. 618 - 627 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

200

µM

fatty acid synthase [chicken]:Wild

Enzymology inhibition

Journal of the Brazilian...

Title/Abstract Full Text View citing articles Show Details

Jiang, He-Zhong; Ma, Qing-Yun; Fan, Hui-Jin; Liang, Wen-Juan; Huang, Sheng-Zhuo; Dai, Hao-Fu; Wang, Peng-Cheng; Ma, Xiao-Feng; Zhao, You-Xing

Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 5 p. 889 - 893 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

16.2

%

In Vitro (others)

500 µM

Antioxidant

Journal of Inorganic Bio...

Title/Abstract Full Text View citing articles Show Details

Perron, Nathan R.; Garcia, Carla R.; Pinzon, Julio R.; Chaur, Manuel N.; Brumaghim, Julia L.

Journal of Inorganic Biochemistry, 2011 , vol. 105, # 5 p. 745 - 753 Title/Abstract Full Text View citing articles Show Details

2.11

% Inhibition

42.9

%

neutrophil

In Vitro (others)

1000 µg/mL

Antiinflammatory

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Ngoumfo, Rostand Manfouo; Ngounou, Georges Eric; Tchamadeu, Chimene Victoire; Qadir, Muhammad Irfan; Mbazoa, Celine Djama; Begum, Afshan; Ngninzeko, Fernande Ngounou; Lontsi, David; Choudhary, Muhammad Iqbal

Journal of Natural Products, 2008 , vol. 71, # 11 p. 1906 - 1910 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1000

µg/mL

neutrophil

In Vitro (others)

Antiinflammatory

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Ngoumfo, Rostand Manfouo; Ngounou, Georges Eric; Tchamadeu, Chimene Victoire; Qadir, Muhammad Irfan; Mbazoa, Celine Djama; Begum, Afshan; Ngninzeko, Fernande Ngounou; Lontsi, David; Choudhary, Muhammad Iqbal

Journal of Natural Products, 2008 , vol. 71, # 11 p. 1906 - 1910 Title/Abstract Full Text View citing articles Show Details

4.95

EC50

0.0019

mg/mL

In Vitro (others)

Antioxidant

Carbohydrate Research, 2...

Title/Abstract Full Text View citing articles Show Details

Pasanphan, Wanvimol; Buettner, Garry R.; Chirachanchai, Suwabun

Carbohydrate Research, 2010 , vol. 345, # 1 p. 132 - 140 Title/Abstract Full Text View citing articles Show Details

4.79

IC50

16.07

µM

In Vitro (others)

Antioxidant

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details


Park, Kwan Hee; Kim, Sung Kyu; Choi, Sun Eun; Kwon, Joo Hee; Oh, Myung Hwan; Lee, Min Won

Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 9 p. 1227 - 1231 Title/Abstract Full Text View citing articles Show Details

pX

Parameter % Inhibition

Value (qual)

Value (quant)

Unit

23.36

µM

Action on Target

Target

Tissue/Organ

Cell

Bioassay

RAW 264.7 cell line

In Vitro (others)

Dose

Effect

Reference (expand all/collapse all) Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Park, Kwan Hee; Kim, Sung Kyu; Choi, Sun Eun; Kwon, Joo Hee; Oh, Myung Hwan; Lee, Min Won

Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 9 p. 1227 - 1231 Title/Abstract Full Text View citing articles Show Details

ED50

16

µg

Hyaluronidase:Wild

Enzymology inhibition

Antidote

Molecules (Basel, Switze...

Title/Abstract Full Text Show Details

Enzymology inhibition

Antidote

Molecules (Basel, Switze...

Title/Abstract Full Text Show Details

Enzymology inhibition

Antidote

Molecules (Basel, Switze...

Title/Abstract Full Text Show Details

Enzymology inhibition

Antidote

Molecules (Basel, Switze...

Title/Abstract Full Text Show Details

In Vitro (others)

Antidote

Molecules (Basel, Switze...

Title/Abstract Full Text Show Details

In Vitro (others)

Antidote

Molecules (Basel, Switze...

Title/Abstract Full Text Show Details

Enzymology inhibition

Antidiabetic

Chemistry of Natural Com...

Title/Abstract Full Text View citing articles Show Details

In Vitro (others)

Antioxidant

Chemistry of Natural Com...

Title/Abstract Full Text View citing articles Show Details

Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart

Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details

ED50

14.8

µg

Hyaluronidase:Wild

Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart

Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details

ED50

1.7

µg

Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart

Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details

ED50

4.5

µg

Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart

Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details

ED50

66

µg

phospholipase A2:Wild

Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart

Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details

ED50

123.5

µg

phospholipase A2:Wild

Leanpolchareanchai, Jiraporn; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart

Molecules (Basel, Switzerland), 2009 , vol. 14, # 4 p. 1404 - 1422 Title/Abstract Full Text Show Details

4.61

IC50

24.3

µM

alphaglucosidase:Wild

Zhao, Jun; Zhou, Xuan-Wei; Chen, Xiao-Bin; Wang, Quan-Xi

Chemistry of Natural Compounds, 2009 , vol. 45, # 2 p. 244 - 246 Title/Abstract Full Text View citing articles Show Details

5.19

IC50

6.47

µM

Si, Chuan-Ling; Zhang, Yu; Zhu, Zhen-Yuan; Liu, Shi-Chao

Chemistry of Natural Compounds, 2011 , vol. 47, # 3 p. 442 - 445


Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µg/mL

Enzymology inhibition

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Ngamukote, Sathaporn; Maekynen, Kittana; Thilawech, Thavaree; Adisakwattana, Sirichai

Molecules, 2011 , vol. 16, # 6 p. 5054 - 5061 Title/Abstract Full Text View citing articles Show Details

% Stimulation

@

Agonist

Beta-arrestin2:Chimera + G-protein coupled receptor 35 [human]:Chimera

U-2 OS

Protein interaction

Patent: WO2013/22740 A...

Title/Abstract Full Text Show Details

Enzymology inhibition

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

CORNING INCORPORATED; DENG, Huayun; FANG, Ye; HU, Haibei

Patent: WO2013/22740 A2, 2013 ; Title/Abstract Full Text Show Details

3.31

IC50

487

µM

Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild

Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details

3.58

Ki

264

µM

Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild

Enzymology inhibition

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details

3.14

% Inhibition

57.8

%

Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild

Enzymology inhibition

1000 µM

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

12.9

%

Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild

Enzymology inhibition

10 µM

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details

3.69

% Inhibition

33

%

Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild

Enzymology inhibition

100 µM

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Fan, Wenzhe; Tezuka, Yasuhiro; Komatsu, Katsuko; Namba, Tsuneo; Kadota, Shigetoshi

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 2 p. 157 - 161 Title/Abstract Full Text View citing articles Show Details

3.89

EC50

128

µM

Peroxisome proliferator-activated receptor, gamma:Wild

In Vitro (others)

Patent: US2008/131534 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Melbrosin International Produktions- und Vertriebs GesmbH and Co KG

Patent: US2008/131534 A1, 2008 ; Title/Abstract Full Text Show Details

4

IC50

100

µM

enzyme:Wild + Reverse transcriptase [Human immunodeficiency virus]:Wild

Misra, Anju P.; Mathad, Vijayavitthal T.; Raj, Kanwal; Bhaduri, Amiya P.; Tiwari, Rashmi; Srivastava, Anuradha; Mehrotra

Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 21 p. 2763 - 2772 Title/Abstract Full Text View citing articles Show Details


4.3

% Inhibition

25 - 50

%

CDK5/Cyclin (p35):Wild + CDK5/Cyclin (CDK5):Wild

Enzymology inhibition

30 µM

Patent: WO2011/69334 A...

Title/Abstract Full Text Show Details

Patent: WO2011/69334 A...

Title/Abstract Full Text Show Details

Patent: WO2011/69334 A...

Title/Abstract Full Text Show Details

Patent: WO2011/69334 A...

Title/Abstract Full Text Show Details

Immunosuppressant

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; IP, Nancy Yuk-Yu; IP, Fanny Chui-Fun; FU, Wing Yu; FU, Guangmiao

Patent: WO2011/69334 A1, 2011 ; Title/Abstract Full Text Show Details

4.3

% Inhibition

25 - 50

%

CDK5/Cyclin (p25):Wild + CDK5/Cyclin (CDK5):Wild

Enzymology inhibition

30 µM

THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; IP, Nancy Yuk-Yu; IP, Fanny Chui-Fun; FU, Wing Yu; FU, Guangmiao

Patent: WO2011/69334 A1, 2011 ; Title/Abstract Full Text Show Details

4.39

IC50

40.6

µM

CDK5/Cyclin (p25):Wild + CDK5/Cyclin (CDK5):Wild

Enzymology inhibition

THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; IP, Nancy Yuk-Yu; IP, Fanny Chui-Fun; FU, Wing Yu; FU, Guangmiao

Patent: WO2011/69334 A1, 2011 ; Title/Abstract Full Text Show Details

3.95

% Inhibition

64.19

%

CDK5/Cyclin (p25):Wild + CDK5/Cyclin (CDK5):Wild

Enzymology inhibition

200 µM

THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY; IP, Nancy Yuk-Yu; IP, Fanny Chui-Fun; FU, Wing Yu; FU, Guangmiao

Patent: WO2011/69334 A1, 2011 ; Title/Abstract Full Text Show Details

1.52

IC50

30

mM

In Vitro (others)

0 mM

Hamada, Shin-Ichi; Kataoka, Takao; Woo, Je-Tae; Yamada, Atsushi; Yoshida, Takashi; Nishimura, Toshio; Otake, Noboru; Nagai, Kazuo

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 9 p. 1017 - 1019 Title/Abstract Full Text View citing articles Show Details

4

MIC

100

µM

In Vitro (others)

Toxic

Bulletin of Environmenta...

Title/Abstract Full Text View citing articles Show Details

Schrader; Harries

Bulletin of Environmental Contamination and Toxicology, 2001 , vol. 66, # 6 p. 801 - 807 Title/Abstract Full Text View citing articles Show Details

3

MIC

1000

µM

In Vitro (others)

Toxic

Bulletin of Environmenta...

Title/Abstract Full Text View citing articles Show Details

Schrader; Harries

Bulletin of Environmental Contamination and Toxicology, 2001 , vol. 66, # 6 p. 801 - 807 Title/Abstract Full Text View citing articles Show Details

2.23

MIC

1000

mg/L

In Vitro (others)

Bacteriostatic

Planta Medica, 1999 , v...

Title/Abstract Full Text View citing articles Show Details

Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel

Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

500

mg/L

In Vitro (others)

Bacteriostatic

Planta Medica, 1999 , v...

Title/Abstract Full Text View citing articles Show Details

Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel

Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details

1.93

MIC

2000

mg/L

In Vitro (others)

Bacteriostatic

Planta Medica, 1999 , v...

Title/Abstract Full Text View citing articles Show Details


Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel

Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

500

mg/L

In Vitro (others)

Bacteriostatic

Planta Medica, 1999 , v...

Title/Abstract Full Text View citing articles Show Details

Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel

Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

500

mg/L

In Vitro (others)

Bacteriostatic

Planta Medica, 1999 , v...

Title/Abstract Full Text View citing articles Show Details

Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel

Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

500

mg/L

In Vitro (others)

Bacteriostatic

Planta Medica, 1999 , v...

Title/Abstract Full Text View citing articles Show Details

Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel

Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

250

mg/L

In Vitro (others)

Fungistatic

Planta Medica, 1999 , v...

Title/Abstract Full Text View citing articles Show Details

Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel

Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details

2.23

MIC

1000

mg/L

In Vitro (others)

Fungistatic

Planta Medica, 1999 , v...

Title/Abstract Full Text View citing articles Show Details

Kolodziej, Herbert; Kayser, Oliver; Latte, Klaus Peter; Ferreira, Daneel

Planta Medica, 1999 , vol. 65, # 5 p. 444 - 446 Title/Abstract Full Text View citing articles Show Details

3

IC50

1000

µM

In Vitro (others)

30 µM

Mutagenic

Mutation Research - Fund...

Title/Abstract Full Text View citing articles Show Details

Armstrong; Galloway

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1997 , vol. 373, # 2 p. 167 - 178 Title/Abstract Full Text View citing articles Show Details

5.09

IC50

8.2

µM

In Vitro (others)

1 µM

Planta Medica, 2007 , v...

Title/Abstract Full Text View citing articles Show Details

Mi, Kyeong Lee; Hee, Young Jeon; Ki, Yong Lee; Seung, Hyun Kim; Choong, Je Ma; Sang, Hyun Sung; Lee, Heum-Sook; Mi, Jung Park; Young, Choong Kim

Planta Medica, 2007 , vol. 73, # 8 p. 782 - 786 Title/Abstract Full Text View citing articles Show Details

5.3

EC50

5

µM

In Vitro (others)

Antibiotic

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Srivastava, Vandana; Darokar, Mahendra P.; Fatima, Atiya; Kumar; Chowdhury, Chinmay; Saxena, Hari Om; Dwivedi, Gaurav R.; Shrivastava, Kunal; Gupta, Vivek; Chattopadhyay; Luqman, Suaib; Gupta; Negi, Arvind S.; Khanuja, Suman P.S.

Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 518 - 525 Title/Abstract Full Text View citing articles Show Details

5.3

EC50

5

µM

In Vitro (others)

Antibiotic

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Srivastava, Vandana; Darokar, Mahendra P.; Fatima, Atiya; Kumar; Chowdhury, Chinmay; Saxena, Hari Om; Dwivedi, Gaurav R.; Shrivastava, Kunal; Gupta, Vivek; Chattopadhyay; Luqman, Suaib; Gupta; Negi, Arvind S.;


Khanuja, Suman P.S.

Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 518 - 525 Title/Abstract Full Text View citing articles Show Details

5.17

IC50

6.828

µM

glycogen phosphorylase:Wild

In Vitro (others)

Planta Medica, 2008 , v...

Title/Abstract Full Text View citing articles Show Details

Li, Jun; Lu, Yuanyuan; Su, Xiaojian; Li, Fu; She, Zhigang; He, Xingcun; Lin, Yongcheng

Planta Medica, 2008 , vol. 74, # 3 p. 287 - 289 Title/Abstract Full Text View citing articles Show Details

5.33

IC50

4.673

µM

alphaglucosidase:Wild

In Vitro (others)

Planta Medica, 2008 , v...

Title/Abstract Full Text View citing articles Show Details

Li, Jun; Lu, Yuanyuan; Su, Xiaojian; Li, Fu; She, Zhigang; He, Xingcun; Lin, Yongcheng

Planta Medica, 2008 , vol. 74, # 3 p. 287 - 289 Title/Abstract Full Text View citing articles Show Details

3.95

IC50

112

µM

alphaglucosidase:Wild

Enzymology inhibition

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Sancheti, Shruti; Sancheti, Sandesh; Bafna, Mayur; Seo, Sung-Yum

Medicinal Chemistry Research, 2011 , vol. 20, # 8 p. 1181 - 1187 Title/Abstract Full Text View citing articles Show Details

Km

0

mM

Polyphenol oxidase:Wild

Enzymology substrate

Food Chemistry, 2011 , ...

Title/Abstract Full Text View citing articles Show Details

Altunkaya, Arzu

Food Chemistry, 2011 , vol. 128, # 3 p. 754 - 760 Title/Abstract Full Text View citing articles Show Details

Vmax

0

min-1

Polyphenol oxidase:Wild

Enzymology substrate

Food Chemistry, 2011 , ...

Title/Abstract Full Text View citing articles Show Details

Altunkaya, Arzu

Food Chemistry, 2011 , vol. 128, # 3 p. 754 - 760 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1000

µg/mL

Alpha amylase:Wild

Enzymology inhibition

Journal of Natural Medic...

Title/Abstract Full Text View citing articles Show Details

Ochir, Sarangowa; Nishizawa, Makoto; Jae Park, Byoung; Ishii, Kouta; Kanazawa, Tsutomu; Funaki, Minoru; Yamagishi, Takashi

Journal of Natural Medicines, 2010 , vol. 64, # 3 p. 275 - 280 Title/Abstract Full Text View citing articles Show Details

3.08

IC50

143

µg/mL

alphaglucosidase:Wild

Enzymology inhibition

Journal of Natural Medic...

Title/Abstract Full Text View citing articles Show Details

Ochir, Sarangowa; Nishizawa, Makoto; Jae Park, Byoung; Ishii, Kouta; Kanazawa, Tsutomu; Funaki, Minoru; Yamagishi, Takashi

Journal of Natural Medicines, 2010 , vol. 64, # 3 p. 275 - 280 Title/Abstract Full Text View citing articles Show Details

1.93

MBC

2

mg/mL

In Vitro (others)

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details

ZI

24

mm

In Vitro (others)

1.50000 mg

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details


2.23

MIC

1

mg/mL

In Vitro (others)

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details

1.93

MBC

2

mg/mL

In Vitro (others)

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details

ZI

25

mm

In Vitro (others)

1.50000 mg

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details

2.23

MIC

1

mg/mL

In Vitro (others)

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details

1.63

MBC

4

mg/mL

In Vitro (others)

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details

ZI

22

mm

In Vitro (others)

1.50000 mg

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details

1.93

MIC

2

mg/mL

In Vitro (others)

Antimicrobial

Journal of Molecular Cat...

Title/Abstract Full Text View citing articles Show Details

Bouaziz, Ahlem; Horchani, Habib; Salem, Nadia Ben; Chaari, Ali; Chaabouni, Moncef; Gargouri, Youssef; Sayari, Adel

Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 67, # 3-4 p. 242 - 250 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

RAW 264.7 cell line

In Vitro (others)

Antiinflammatory

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Yang, Zhi-Gang; Jia, Liu-Nan; Shen, Yan; Ohmura, Atsuko; Kitanaka, Susumu

Molecules, 2011 , vol. 16, # 10 p. 8305 - 8318 Title/Abstract Full Text View citing articles Show Details

3.78

% Inhibition

37.4

%

Angiotensinconverting enzyme:Wild

Enzymology inhibition

100 µM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

500

µM

Angiotensinconverting enzyme:Wild

Enzymology inhibition

100 µM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details


Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details

3.07

% Inhibition

41.1

%

Neprilysin:Wild

Enzymology inhibition

100 µg/mL

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details

3.32

IC50

480

µM

Neprilysin:Wild

Enzymology inhibition

100 µg/mL

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details

5.55

IC50

2.8

µM

neutrophil

Flux release

5 µg/mL

Antiinflammatory

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details

5.38

IC50

4.2

µM

neutrophil

In Vitro (others)

0.200000 µg/mL

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details

3.48

% Stimulation

63.71

%

Agonist

estrogen receptor [human]:Wild

MVLN cell line

Transactivation assay

100 µg/mL

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Liu, Li; Ma, Hongyue; Tang, Yuping; Chen, Wenxing; Lu, Yin; Guo, Jianming; Duan, Jin-Ao

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 154 - 163 Title/Abstract Full Text View citing articles Show Details

5

% Stimulation

92.19

%

Agonist

estrogen receptor [human]:Wild

MVLN cell line

Transactivation assay

20 µg/mL

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Liu, Li; Ma, Hongyue; Tang, Yuping; Chen, Wenxing; Lu, Yin; Guo, Jianming; Duan, Jin-Ao

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 154 - 163 Title/Abstract Full Text View citing articles Show Details

IC50

275

µg

In Vitro (others)

Antimutagenic

Mutation Research - Gene...

Title/Abstract Full Text View citing articles Show Details

Kaur, Simran; Grover; Singh, Majar; Kaur, Satwinderjeet

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 1998 , vol. 419, # 1-3 p. 169 - 179 Title/Abstract Full Text View citing articles Show Details

5.25

IC50

0.95

mg/L

In Vitro (others)

Antioxidant

Phytochemistry, 2008 , ...

Title/Abstract Full Text View citing articles Show Details

Agnihotri, Vijai K.; ElSohly, Hala N.; Khan, Shabana I.; Smillie, Troy J.; Khan, Ikhlas A.; Walker, Larry A.

Phytochemistry, 2008 , vol. 69, # 10 p. 2061 - 2066 Title/Abstract Full Text View citing articles Show Details

3.23

IC50

100

mg/L

In Vitro (others)

Antioxidant

Phytochemistry, 2007 , ...

Title/Abstract Full Text View citing articles Show Details

Thuong, Phuong Thien; Kang, Ho Jeong; Na, MinKyun; Jin, WenYi; Youn, Ui Jung; Seong, Yeon Hee; Song, Kyung-Sik; Min, Byung-Sun; Bae, KiHwan

Phytochemistry, 2007 , vol. 68, # 19 p. 2432 - 2438


Title/Abstract Full Text View citing articles Show Details

2.77

IC50

1700

µM

Angiotensinconverting enzyme:Wild

In Vitro (others)

10 µM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Actis-Goretta, Lucas; Ottaviani, Javier I.; Fraga, Cesar G.

Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 1 p. 229 - 234 Title/Abstract Full Text View citing articles Show Details

2.62

IC50

0.409

g/L

erythrocyte

In Vitro (others)

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Hamauzu, Yasunori; Inno, Takanori; Kume, Chihiro; Irie, Miho; Hiramatsu, Kohzy

Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 3 p. 765 - 772 Title/Abstract Full Text View citing articles Show Details

1

% Stimulation

NA

Agonist

aryl hydrocarbon receptor [human]:Wild

Transactivation assay

Patent: WO2007/110241 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

JUNGBAUER, Alois; MEDJAKOVIC, Svjetlana; ZÖCHLING, Alfred

Patent: WO2007/110241 A1, 2007 ; Title/Abstract Full Text Show Details

1.68

IC50

21

mM

fatty acid synthase:Wild

Wang, Xuan; Song, Ke-Sheng; Guo, Qing-Xiang; Tian, Wei-Xi

Biochemical Pharmacology, 2003 , vol. 66, # 10 p. 2039 - 2047 Title/Abstract Full Text View citing articles Show Details

1.59

IC50

26

mM

fatty acid synthase:Wild

In Vitro (others)

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

Wang, Xuan; Song, Ke-Sheng; Guo, Qing-Xiang; Tian, Wei-Xi

Biochemical Pharmacology, 2003 , vol. 66, # 10 p. 2039 - 2047 Title/Abstract Full Text View citing articles Show Details

1.73

MBC

3200 6400

mg/L

In Vitro (others)

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi; Nihei, Atsuko

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 5 p. 1072 - 1076 Title/Abstract Full Text View citing articles Show Details

2.59

IC50

2600

µM

Neuraminidase:Wild

In Vitro (others)

Planta Medica, 2007 , v...

Title/Abstract Full Text View citing articles Show Details

Li, Xiaofan; Ohtsuki, Takashi; Shindo, Sayaka; Sato, Masaaki; Koyano, Takashi; Preeprame, Srisomporn; Kowithayakorn, Thaworn; Ishibashi, Masami

Planta Medica, 2007 , vol. 73, # 11 p. 1195 - 1196 Title/Abstract Full Text View citing articles Show Details

3.78

EC50

0.165

mM

In Vitro (others)

0.0625000 mM

Toxic

Chemosphere, 2005 , vol...

Title/Abstract Full Text View citing articles Show Details

Kamaya, Yasushi; Fukaya, Yuki; Suzuki, Kyoji

Chemosphere, 2005 , vol. 59, # 2 p. 255 - 261 Title/Abstract Full Text View citing articles Show Details

3.95

EC50

0.112

mM

In Vitro (others)

0.0625000 mM

Toxic

Chemosphere, 2005 , vol...

Title/Abstract Full Text View citing articles Show Details

Kamaya, Yasushi; Fukaya, Yuki; Suzuki, Kyoji

Chemosphere, 2005 , vol. 59, # 2 p. 255 - 261 Title/Abstract Full Text View citing articles Show Details

%

91.86

%

In Vitro (others)

62.5000 µg/mL

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details


Bitis, Leyla; Kultur, Sukran; Melkoglu, Gulay; Ozsoy, Nurten; Can, Ayse

Natural Product Research, 2010 , vol. 24, # 6 p. 580 - 589 Title/Abstract Full Text View citing articles Show Details

3.89

EC50

22.2

µg/mL

In Vitro (others)

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Bitis, Leyla; Kultur, Sukran; Melkoglu, Gulay; Ozsoy, Nurten; Can, Ayse

Natural Product Research, 2010 , vol. 24, # 6 p. 580 - 589 Title/Abstract Full Text View citing articles Show Details

4.12

IC50

76

µM

HEK cell line

Transactivation assay

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Morais, Mauro C. C.; Luqman, Suaib; Kondratyuk, Tamara P.; Petronio, Maicon S.; Regasini, Luis O.; Silva, Dulce H. S.; Bolzani, Vanderlan S.; Soares, Christiane P.; Pezzuto, John M.

Natural Product Research, 2010 , vol. 24, # 18 p. 1758 - 1765 Title/Abstract Full Text View citing articles Show Details

IC50

>

500

µmol

Tyrosinase:Wild

Enzymology inhibition

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

IC50

14

µmol

In Vitro (others)

Antiinflammatory

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

2.17

Ki

6.7

mM

In Vitro (others)

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Pastore, Donato; Laus, Maura N.; Tozzi, Damiana; Fogliano, Vincenzo; Soccio, Mario; Flagella, Zina

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 20 p. 9682 - 9692 Title/Abstract Full Text View citing articles Show Details

4.91

IC50

2.1

µg/mL

HL-60 cell line

In Vitro (others)

0.0100000 µg/mL

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Dobroslawa, Bialonska; Kasimsetty, Sashi G.; Khan, Shabana I.; Daneel, Ferreira

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 21 p. 10181 - 10186 Title/Abstract Full Text View citing articles Show Details

4.7

MEC

20

µM

erythrocyte

In Vitro (others)

10 µM

Antihemolytic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details

3.23

MFC

0.59

µmol/mL

In Vitro (others)

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

0.295

µmol/mL

In Vitro (others)

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422


Title/Abstract Full Text View citing articles Show Details

3.87

IC50

136

µM

Proto-oncogene tyrosine-protein kinase Src [human]:Wild

thrombocyte

Enzymology inhibition

Journal of enzyme inhibi...

Title/Abstract Full Text Show Details

Enzymology inhibition

Patent: WO2004/9833 A2...

Title/Abstract Full Text Show Details

Enzymology inhibition

100 µM

Patent: WO2004/9833 A2...

Title/Abstract Full Text Show Details

In Vitro (others)

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Palacios; Cespon; Martin De La Vega; Roy; Serrano; Salinas; Gonzalez-Porque

Journal of enzyme inhibition, 2001 , vol. 16, # 6 p. 527 - 533 Title/Abstract Full Text Show Details

4.43

IC50

37.5

µM

Inositol polyphosphate multikinase [human]:Wild

MAYR, Georg W.; NALASKOWSKI, Marcus M.; HILLEMEIER, Kirsten

Patent: WO2004/9833 A2, 2004 ; Title/Abstract Full Text Show Details

4.03

% Inhibition

52

%

Inositol polyphosphate multikinase [human]:Wild

MAYR, Georg W.; NALASKOWSKI, Marcus M.; HILLEMEIER, Kirsten

Patent: WO2004/9833 A2, 2004 ; Title/Abstract Full Text Show Details

5.23

IC50

5.94

µM

Kubo, Isao; Kinst-Hori, Ikuyo; Kubo, Yumi; Yamagiwa, Yoshiro; Kamikawa, Tadao; Haraguchi, Hiroyuki

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 4 p. 1393 - 1399 Title/Abstract Full Text View citing articles Show Details

2.35

ID50

4.5

mM

Tyrosinase [mushroom]:Wild

In Vitro (others)

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Kinst-Hori, Ikuyo; Kubo, Yumi; Yamagiwa, Yoshiro; Kamikawa, Tadao; Haraguchi, Hiroyuki

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 4 p. 1393 - 1399 Title/Abstract Full Text View citing articles Show Details

4.02

IC50

16.1

mg/L

In Vitro (others)

Antiprotozoal

Planta Medica, 2006 , v...

Title/Abstract Full Text View citing articles Show Details

Cao, Shugeng; Ranarivelo, Lalasoa; Ratsimbason, Michel; Randrianasolo, Sennen; Ratovoson, Fidy; Andrianjafy, Mamisoa; Kingston, David G. I.

Planta Medica, 2006 , vol. 72, # 15 p. 1438 - 1440 Title/Abstract Full Text View citing articles Show Details

4.32

IC50

8.2

mg/L

In Vitro (others)

Antiprotozoal

Planta Medica, 2006 , v...

Title/Abstract Full Text View citing articles Show Details

Cao, Shugeng; Ranarivelo, Lalasoa; Ratsimbason, Michel; Randrianasolo, Sennen; Ratovoson, Fidy; Andrianjafy, Mamisoa; Kingston, David G. I.

Planta Medica, 2006 , vol. 72, # 15 p. 1438 - 1440 Title/Abstract Full Text View citing articles Show Details

4.12

IC50

13

mg/L

A2780 cell line

In Vitro (others)

Cytotoxic

Planta Medica, 2006 , v...

Title/Abstract Full Text View citing articles Show Details

Cao, Shugeng; Ranarivelo, Lalasoa; Ratsimbason, Michel; Randrianasolo, Sennen; Ratovoson, Fidy; Andrianjafy, Mamisoa; Kingston, David G. I.

Planta Medica, 2006 , vol. 72, # 15 p. 1438 - 1440 Title/Abstract Full Text View citing articles Show Details

3.47

% Inhibition

42.2

%

glycerol-3-phosphate dehydrogenase:Wild

3T3-L1 cell line

Enzymology inhibition

250 µM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Hsu, Chin-Lin; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 21 p. 8404 - 8410 Title/Abstract Full Text View citing articles Show Details

3.22

% Inhibition

29.2

%

3T3-L1 cell

In Vitro

250 µM

Journal of Agricultural ...


line

(others)

Title/Abstract Full Text View citing articles Show Details

Hsu, Chin-Lin; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 21 p. 8404 - 8410 Title/Abstract Full Text View citing articles Show Details

2.7

% Inhibition

<

50

%

Tyrosinase:Wild

Enzymology inhibition

2 mM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Liu, Qing; Zhang, Ying-Tun; Yang, Chong-Ren; Xu, Mei

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 2 p. 586 - 590 Title/Abstract Full Text View citing articles Show Details

3.98

IC50

105.41

µM

xanthine oxidase:Wild

In Vitro (others)

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Wu, Nan; Zu, Yuangang; Fu, Yujie; Kong, Yu; Zhao, Jintong; Li, Xiaojuan; Li, Ji; Wink, Michael; Efferth, Thomas

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 8 p. 4737 - 4743 Title/Abstract Full Text View citing articles Show Details

3.58

IC50

261

µM

Tyrosinase:Wild

Enzymology inhibition

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Gao, Da-Fang; Xu, Min; Yang, Chong-Ren; Xu, Mei; Zhang, Ying-Jun

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 15 p. 8820 - 8824 Title/Abstract Full Text View citing articles Show Details

4.3

IC50

50

µM

enzyme:Wild

In Vitro (others)

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Nakai, Masaaki; Fukui, Yuko; Asami, Sumio; Toyoda-Ono, Yoshiko; Iwashita, Takashi; Shibata, Hiroshi; Mitsunaga, Tohru; Hashimoto, Fumio; Kiso, Yoshinobu

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 11 p. 4593 - 4598 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

50

µg/mL

Enzymology inhibition

Fitoterapia, 2009 , vol...

Title/Abstract Full Text View citing articles Show Details

Kim, Hyoung Ja; Lee, Jun Young; Kim, Sung Min; Park, Da-Ae; Jin, Changbae; Hong, Seon Pyo; Lee, Yong Sup

Fitoterapia, 2009 , vol. 80, # 1 p. 73 - 76 Title/Abstract Full Text View citing articles Show Details

3.62

IC50

241

µM

P-selectin [human]:Wild

In Vitro (others)

Patent: EP1481669 A1, ...

Title/Abstract Full Text Show Details

P-selectin [human]:Wild

In Vitro (others)

Patent: EP1481669 A1, ...

Title/Abstract Full Text Show Details

P-selectin [human]:Wild

In Vitro (others)

Patent: EP1481669 A1, ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antioxidant

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

YAMANOUCHI PHARMACEUTICAL CO. LTD.

Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details

5.07

IC50

8.5

µM

YAMANOUCHI PHARMACEUTICAL CO. LTD.

Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details

5.14

IC50

7.2

µM

YAMANOUCHI PHARMACEUTICAL CO. LTD.

Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details

4.4

IC50

40

µM

Ozgova, Sarka; Hermanek, Josef; Gut, Ivan

Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details


4.4

IC50

40

µM

In Vitro (others)

Antioxidant

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

Ozgova, Sarka; Hermanek, Josef; Gut, Ivan

Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details

4.4

IC50

40

µM

In Vitro (others)

Antioxidant

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

Ozgova, Sarka; Hermanek, Josef; Gut, Ivan

Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details

4.1

IC50

80

µM

In Vitro (others)

Antioxidant

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

Ozgova, Sarka; Hermanek, Josef; Gut, Ivan

Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details

5.17

IC50

6.7

µM

In Vitro (others)

Antioxidant

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

Ozgova, Sarka; Hermanek, Josef; Gut, Ivan

Biochemical Pharmacology, 2003 , vol. 66, # 7 p. 1127 - 1137 Title/Abstract Full Text View citing articles Show Details

3.09

IC50

818.6

µM

enzyme:Wild

In Vitro (others)

10 µM

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

Zhang, Kai; Yang, Er-Bin; Tang, Wen-Ying; Wong, Kim Ping; Mack, Peter

Biochemical Pharmacology, 1997 , vol. 54, # 9 p. 1047 - 1053 Title/Abstract Full Text View citing articles Show Details

4.26

IC50

54.7

µM

integrase [Human immunodeficiency virus]:Wild

In Vitro (others)

Planta Medica, 2002 , v...

Title/Abstract Full Text View citing articles Show Details

Ahn, Mi-Jeong; Chul, Young Kim; Ji, Suk Lee; Tae, Gyun Kim; Seung, Hee Kim; Lee, Chong-Kyo; Lee, Bo-Bin; Shin, Cha-Gyun; Huh, Hoon; Kim, Jinwoong

Planta Medica, 2002 , vol. 68, # 5 p. 457 - 459 Title/Abstract Full Text View citing articles Show Details

4

IC50

100

µM

Reverse transcriptase [Human immunodeficiency virus]:Wild

In Vitro (others)

Planta Medica, 2002 , v...

Title/Abstract Full Text View citing articles Show Details

Ahn, Mi-Jeong; Chul, Young Kim; Ji, Suk Lee; Tae, Gyun Kim; Seung, Hee Kim; Lee, Chong-Kyo; Lee, Bo-Bin; Shin, Cha-Gyun; Huh, Hoon; Kim, Jinwoong

Planta Medica, 2002 , vol. 68, # 5 p. 457 - 459 Title/Abstract Full Text View citing articles Show Details

3.44

EC50

360

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

3.22

EC50

600

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

2.94

EC50

1158

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details


Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

2.41

EC50

3865

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

3.19

EC50

640

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

3.11

EC50

780

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

3.13

EC50

740

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

3.08

EC50

840

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

4.57

EC50

27

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

3.86

EC50

137

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

3.3

EC50

500

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459 Title/Abstract Full Text View citing articles Show Details

3.91

EC50

123

µM

In Vitro (others)

1 µM

Germination Effect

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kalinova, Jana; Vrchotova, Nadezda; Triska, Jan

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 16 p. 6453 - 6459


Title/Abstract Full Text View citing articles Show Details

5.23

EC50

1

mg/L

In Vitro (others)

Antiproliferative

Water Research, 2001 , ...

Title/Abstract Full Text View citing articles Show Details

Nakai, Satoshi; Inoue, Yutaka; Hosomi, Masaaki

Water Research, 2001 , vol. 35, # 7 p. 1855 - 1859 Title/Abstract Full Text View citing articles Show Details

Concentration

232

µM

In Vitro (others)

Antioxidant

Food Chemistry, 2012 , ...

Title/Abstract Full Text View citing articles Show Details

Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.

Food Chemistry, 2012 , vol. 133, # 3 p. 697 - 706 Title/Abstract Full Text View citing articles Show Details

5.48

IC50

3.3

µM

In Vitro (others)

Antioxidant

Food Chemistry, 2012 , ...

Title/Abstract Full Text View citing articles Show Details

Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.

Food Chemistry, 2012 , vol. 133, # 3 p. 697 - 706 Title/Abstract Full Text View citing articles Show Details

3.89

IC50

0.00013

M

In Vitro (others)

1.00000E08 M

Inotropic : Negative

Fitoterapia, 2010 , vol...

Title/Abstract Full Text View citing articles Show Details

Lee, Hobeom; Lee, Ji Yun; Suh, Moo Hyun; Sim, Sang-Soo; Lee, Min-Won; Kim, Chang Jong

Fitoterapia, 2010 , vol. 81, # 7 p. 820 - 825 Title/Abstract Full Text View citing articles Show Details

3.47

EC50

335

µM

Hep G2

In Vitro (others)

50 µM

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

4.18

EC50

65.4

µM

Hep G2

In Vitro (others)

10 µM

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

3.5

EC50

318

µM

Hep G2

In Vitro (others)

50 µM

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

3.57

EC50

270 350

µM

Hep G2

In Vitro (others)

50 µM

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

4.19

EC50

64.3

µM

Hep G2

In Vitro (others)

10 µM

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

4.29

EC50

51.3 -

µM

Hep G2

In Vitro

10 µM

Antioxidant

Journal of Agricultural ...


77.3

(others)

Title/Abstract Full Text View citing articles Show Details

Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

5.49

IC50

3.2

µM

In Vitro (others)

0.0100000 mM

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Barreto, Jacqueline C.; Trevisan, Maria T. S.; Hull, William E.; Erben, Gerhard; De Brito, Edy S.; Pfundstein, Beate; Wuertele, Gerd; Spiegelhalder, Bertold; Owen, Robert W.

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 14 p. 5599 - 5610 Title/Abstract Full Text View citing articles Show Details

5.3

EC50

5.01

µM

In Vitro (others)

0.0100000 mM

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Barreto, Jacqueline C.; Trevisan, Maria T. S.; Hull, William E.; Erben, Gerhard; De Brito, Edy S.; Pfundstein, Beate; Wuertele, Gerd; Spiegelhalder, Bertold; Owen, Robert W.

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 14 p. 5599 - 5610 Title/Abstract Full Text View citing articles Show Details

3.09

IC50

821

µM

Tyrosinase:Wild

Enzymology inhibition

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Gao, Da-Fang; Zhang, Ying-Jun; Yang, Chong-Ren; Chen, Ke-Ke; Jiang, Hong-Jian

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 16 p. 7517 - 7521 Title/Abstract Full Text View citing articles Show Details

% Inhibition

97.7

%

In Vitro (others)

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Huang, Din-Wen; Kuo, Yueh-Hsiung; Lin, Fang-Yi; Lin, Yun-Lian; Chiang, Wenchang

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 6 p. 2259 - 2266 Title/Abstract Full Text View citing articles Show Details

5.95

EC50

0.19

µg/mL

In Vitro (others)

Antioxidant

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Huang, Din-Wen; Kuo, Yueh-Hsiung; Lin, Fang-Yi; Lin, Yun-Lian; Chiang, Wenchang

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 6 p. 2259 - 2266 Title/Abstract Full Text View citing articles Show Details

4.38

EC50

7.1

µg/mL

RAW 264.7 cell line

In Vitro (others)

Antiinflammatory

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Huang, Din-Wen; Kuo, Yueh-Hsiung; Lin, Fang-Yi; Lin, Yun-Lian; Chiang, Wenchang

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 6 p. 2259 - 2266 Title/Abstract Full Text View citing articles Show Details

4.44

IC50

6.1

mg/L

In Vitro (others)

0 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen

Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details

4.5

IC50

5.4

mg/L

In Vitro (others)

0 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen

Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details

4.11

IC50

13.2

mg/L

In Vitro (others)

0 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen

Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details

4.55

IC50

4.8

mg/L

In Vitro (others)

0 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen

Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details

4.44

IC50

6.2

mg/L

In Vitro (others)

0 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen

Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details

4.41

IC50

6.6

mg/L

PLC/PRF/5 cell line

In Vitro (others)

0 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Inoue; Suzuki; Sakaguchi; Li; Takeda; Ogihara; Bao Yuan Jiang; Chen

Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 11 p. 1526 - 1530 Title/Abstract Full Text View citing articles Show Details

3.44

MIC

62.5

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.


Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro

Antibiotic

Patent: EP1604660 A1, ...

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5


(others)

Title/Abstract Full Text Show Details

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µg/mL

In Vitro (others)

Antibiotic

Patent: EP1604660 A1, ...

Title/Abstract Full Text Show Details

µM

xanthine oxidase:Wild

In Vitro (others)

50 µM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.74

MIC

31.3

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.44

MIC

62.5

Alps Pharmaceutical Ind. Co. Ltd.

Patent: EP1604660 A1, 2005 ; Title/Abstract Full Text Show Details

3.7

IC50

200

Lin, Jen-Kun; Chen, Ping-Chung; Ho, Chi-Tang; Lin-Shiau, Shoei-Yn


Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 7 p. 2736 - 2743 Title/Abstract Full Text View citing articles Show Details

EC50

3.8

µg

In Vitro (others)

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Pandurangan; Bose, Chinchu; Banerji

Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5328 - 5330 Title/Abstract Full Text View citing articles Show Details

2.15

IC50

7.1

mM

20S Proteasome [human]:Wild

JURKAT

Enzymology inhibition

Patent: US2002/151582 ...

Title/Abstract Full Text Show Details

Prolyl endopeptidase:Wild

Enzymology inhibition

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Dou, Q. Ping; Nam, Sangkil; Smith, David M.

Patent: US2002/151582 A1, 2002 ; Title/Abstract Full Text Show Details

1

IC50

>

400

µM

Lee, Seung-Ho; Jun, Mira; Choi, Ji-Young; Yang, Eun-Ju; Hur, Jong-Moon; Bae, Kihwan; Seong, Yeon-Hee; Huh, Tae-Lin; Song, Kyung-Sik

Archives of Pharmacal Research, 2007 , vol. 30, # 7 p. 827 - 833 Title/Abstract Full Text View citing articles Show Details

5

% Inhibition

@

Esterase [rabbit]:Wild

liver

Enzymology inhibition

10 µM

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Chieli, Elisabetta; Romiti, Nadia; Rodeiro, Idania; Garrido, Gabino

Food and Chemical Toxicology, 2009 , vol. 47, # 11 p. 2703 - 2710 Title/Abstract Full Text View citing articles Show Details

3.69

IC50

206

µM

Chitin synthase 2:Wild

In Vitro (others)

Planta Medica, 2001 , v...

Title/Abstract Full Text View citing articles Show Details

Hwang; Ahn; Lee; Kim; Bok

Planta Medica, 2001 , vol. 67, # 6 p. 501 - 504 Title/Abstract Full Text View citing articles Show Details

1.73

MBC

3200

mg/L

In Vitro (others)

Antimicrobial

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Xiao, Ping; Fujita, Ken'ichi

Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 113 - 116 Title/Abstract Full Text View citing articles Show Details

2.42

IC50

644

µg/mL

Tyrosinase [mushroom]:Wild

In Vitro (others)

Molecules (Basel, Switze...

Title/Abstract Full Text Show Details

In Vitro (others)

1000 µM

Antiproliferative

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Nithitanakool, Saruth; Pithayanukul, Pimolpan; Bavovada, Rapepol; Saparpakorn, Patchreenart

Molecules (Basel, Switzerland), 2009 , vol. 14, # 1 p. 257 - 265 Title/Abstract Full Text Show Details

4.36

IC50

43.3

µM

Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1000

µM

Hyaluronidase [taurine cattle]:Wild

Enzymology inhibition

Bioscience, Biotechnolog...

Title/Abstract Full Text View citing articles Show Details

Barla, Florin; Higashijima, Hayato; Funai, Shingo; Sugimoto, Keiichiro; Harada, Naoki; Yamaji, Ryoichi; Fujita, Tomoyuki; Nakano, Yoshihisa; Inui, Hiroshi

Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 10 p. 2335 - 2337 Title/Abstract Full Text View citing articles Show Details

2.68

IC50

2.07

mM

Matrix metalloproteinase-

Enzymology inhibition

Bioscience, Biotechnolog...

Title/Abstract Full Text View citing articles Show Details


9:Wild

Barla, Florin; Higashijima, Hayato; Funai, Shingo; Sugimoto, Keiichiro; Harada, Naoki; Yamaji, Ryoichi; Fujita, Tomoyuki; Nakano, Yoshihisa; Inui, Hiroshi

Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 10 p. 2335 - 2337 Title/Abstract Full Text View citing articles Show Details

4.73

EC50

18.5

µM

In Vitro (others)

Antioxidant

Bioscience, Biotechnolog...

Title/Abstract Full Text View citing articles Show Details

Barla, Florin; Higashijima, Hayato; Funai, Shingo; Sugimoto, Keiichiro; Harada, Naoki; Yamaji, Ryoichi; Fujita, Tomoyuki; Nakano, Yoshihisa; Inui, Hiroshi

Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 10 p. 2335 - 2337 Title/Abstract Full Text View citing articles Show Details

5.17

IC50

6.7

µM

In Vitro (others)

Antioxidant

Anti-Cancer Drugs, 2011 ...

Title/Abstract Full Text View citing articles Show Details

Soucek, Pavel; Kondrova, Eliska; Hermanek, Josef; Stopka, Pavel; Boumendjel, Ahcene; Ueng, Yune-Fang; Gut, Ivan

Anti-Cancer Drugs, 2011 , vol. 22, # 2 p. 176 - 184 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

40

µM

In Vitro (others)

Antioxidant

Anti-Cancer Drugs, 2011 ...

Title/Abstract Full Text View citing articles Show Details

Soucek, Pavel; Kondrova, Eliska; Hermanek, Josef; Stopka, Pavel; Boumendjel, Ahcene; Ueng, Yune-Fang; Gut, Ivan

Anti-Cancer Drugs, 2011 , vol. 22, # 2 p. 176 - 184 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

200

µg/mL

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.03

MIC

1600

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.33

MIC

800

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.63

MIC

400

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.33

MIC

800

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.63

MIC

400

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.63

MIC

400

µg/mL


KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.63

MIC

400

µg/mL

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antibiotic

Patent: WO2006/126675 ...

Title/Abstract Full Text Show Details

In Vitro (others)

Antiproliferative

Patent: WO2012/21981 A...

Title/Abstract Full Text Show Details

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.63

MIC

400

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.63

MIC

400

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.63

MIC

400

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.93

MIC

200

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.03

MIC

1600

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

2.33

MIC

800

µg/mL

KYONO, Fumiyo; SUEMOTO, Yasuo; TAKAYAMA, Satoru; TAKEUCHI, Makoto

Patent: WO2006/126675 A1, 2006 ; Title/Abstract Full Text Show Details

4.05

IC50

89.3

µM

Caco-2

FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC; UNIVERSITY OF RHODE ISLAND; SEERAM, Navindra, P.; LI, Liya; BELAND, Genevieve; BARBEAU, Julie

Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details

pX

Parameter

4.19

IC50

Value (qual)

Value (quant)

Unit

64.9

µM

Action on Target

Target

Tissue/Organ

Cell

Bioassay

HCT 116 cell line

In Vitro (others)

Dose

Effect

Reference (expand all/collapse all)

Antiproliferative

Patent: WO2012/21981 A...

Title/Abstract Full Text Show Details

FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC; UNIVERSITY OF RHODE ISLAND; SEERAM, Navindra, P.; LI, Liya; BELAND, Genevieve; BARBEAU, Julie

Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details

4.05

IC50

89.3

µM

Caco-2

In Vitro (others)

Antiproliferative

Patent: WO2012/21981 A...

Title/Abstract Full Text Show Details


SEERAM, Navindra, P.; LI, Liya; BÉ LAND, Geneviè ve; BARBEAU, Julie

Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details

4.19

IC50

64.9

µM

HCT 116 cell line

In Vitro (others)

Antiproliferative

Patent: WO2012/21981 A...

Title/Abstract Full Text Show Details

Caco-2

In Vitro (others)

Antiproliferative

Patent: WO2012/21981 A...

Title/Abstract Full Text Show Details

In Vitro (others)

3200 mg/L

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

SEERAM, Navindra, P.; LI, Liya; BÉ LAND, Geneviè ve; BARBEAU, Julie

Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details

4.05

IC50

89.3

µM

SEERAM, Navindra, P.; LI, Liya; BÉ LAND, Geneviè ve; BARBEAU, Julie

Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details

2.03

MBC

1600

mg/L

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 23 p. 6692 - 6696 Title/Abstract Full Text View citing articles Show Details

4.5

IC50

31.7

µM

In Vitro (others)

50 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details

5.28

IC50

5.2

µM

enzyme:Wild

In Vitro (others)

Phytochemistry, 2007 , ...

Title/Abstract Full Text View citing articles Show Details

Wansi, Jean Duplex; Lallemand, Marie-Christine; Chiozem, David Daco; Toze, Flavien Aristide A.; Mbaze, Luc Meva'a; Naharkhan, Shamsun; Iqbal, Muhammad Choudhary; Tillequin, Francois; Wandji, Jean; Fomum, Zacharias Tanee

Phytochemistry, 2007 , vol. 68, # 15 p. 2096 - 2100 Title/Abstract Full Text View citing articles Show Details

3.71

IC50

194.4

µM

enzyme:Wild

In Vitro (others)

Phytochemistry, 2007 , ...

Title/Abstract Full Text View citing articles Show Details

Wansi, Jean Duplex; Lallemand, Marie-Christine; Chiozem, David Daco; Toze, Flavien Aristide A.; Mbaze, Luc Meva'a; Naharkhan, Shamsun; Iqbal, Muhammad Choudhary; Tillequin, Francois; Wandji, Jean; Fomum, Zacharias Tanee

Phytochemistry, 2007 , vol. 68, # 15 p. 2096 - 2100 Title/Abstract Full Text View citing articles Show Details

4.81

IC50

15.6

µM

enzyme:Wild

In Vitro (others)

Phytochemistry, 2007 , ...

Title/Abstract Full Text View citing articles Show Details

Wansi, Jean Duplex; Lallemand, Marie-Christine; Chiozem, David Daco; Toze, Flavien Aristide A.; Mbaze, Luc Meva'a; Naharkhan, Shamsun; Iqbal, Muhammad Choudhary; Tillequin, Francois; Wandji, Jean; Fomum, Zacharias Tanee

Phytochemistry, 2007 , vol. 68, # 15 p. 2096 - 2100 Title/Abstract Full Text View citing articles Show Details

4.28

IC50

52.5

µM

In Vitro (others)

Antioxidant

Arzneimittel-Forschung/D...

Title/Abstract Full Text View citing articles Show Details

Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira

Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details

3.39

EC50

404.3

µM

VERO

In Vitro (others)

Anti-Herpes

Arzneimittel-Forschung/D...

Title/Abstract Full Text View citing articles Show Details

Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira


Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details

3.1

EC50

789.91

µM

VERO

In Vitro (others)

Anti-Herpes

Arzneimittel-Forschung/D...

Title/Abstract Full Text View citing articles Show Details

Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira

Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details

2.98

CC50

1048.14

µM

VERO

In Vitro (others)

3.91000 mg/L

Cytotoxic

Arzneimittel-Forschung/D...

Title/Abstract Full Text View citing articles Show Details

Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira

Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details

2.57

IC50

458.9

mg/L

enzyme:Wild

In Vitro (others)

Carbohydrate Research, 2...

Title/Abstract Full Text View citing articles Show Details

Shinde, Jayantrao; Taldone, Tony; Barletta, Michael; Kunaparaju, Naveen; Hu, Bo; Kumar, Sunil; Placido, Jessica; Zito, S. William

Carbohydrate Research, 2008 , vol. 343, # 7 p. 1278 - 1281 Title/Abstract Full Text View citing articles Show Details

3.5

LC50

54.3

ppm

In Vitro (others)

Toxic

Fitoterapia, 2004 , vol...

Title/Abstract Full Text View citing articles Show Details

Urrea-Bulla; Suarez M; Moreno-Murillo

Fitoterapia, 2004 , vol. 75, # 3-4 p. 392 - 394 Title/Abstract Full Text View citing articles Show Details

3.3

IC50

500

µM

enzyme:Wild

In Vitro (others)

Planta Medica, 2004 , v...

Title/Abstract Full Text View citing articles Show Details

Kiss, Anna; Kowalski, Jozef; Melzig, Matthias F.

Planta Medica, 2004 , vol. 70, # 10 p. 919 - 923 Title/Abstract Full Text View citing articles Show Details

3.32

IC50

480

µM

enzyme:Wild

In Vitro (others)

Planta Medica, 2004 , v...

Title/Abstract Full Text View citing articles Show Details

Kiss, Anna; Kowalski, Jozef; Melzig, Matthias F.

Planta Medica, 2004 , vol. 70, # 10 p. 919 - 923 Title/Abstract Full Text View citing articles Show Details

5

% Inhibition

26.6 47.7

%

Hep G2

In Vitro (others)

1 µg/mL

Antiviral

Asian Journal of Chemist...

Title/Abstract Full Text View citing articles Show Details

Xiang, Zhao Bao; Mo, Hai Qing; Qu, Zhong Tang; Xu, Hong Mei; Jiang, Hum Zhong

Asian Journal of Chemistry, 2011 , vol. 23, # 8 p. 3759 - 3760 Title/Abstract Full Text View citing articles Show Details

5.13

% Inhibition

20.3 68.5

%

Hep G2

In Vitro (others)

1 µg/mL

Antiviral

Asian Journal of Chemist...

Title/Abstract Full Text View citing articles Show Details

Xiang, Zhao Bao; Mo, Hai Qing; Qu, Zhong Tang; Xu, Hong Mei; Jiang, Hum Zhong

Asian Journal of Chemistry, 2011 , vol. 23, # 8 p. 3759 - 3760 Title/Abstract Full Text View citing articles Show Details

4.65

IC50

22.2

µM

G-protein coupled receptor 35:Wild

HT-29

In Vitro (others)

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Deng, Huayun; Fang, Ye

Naunyn-Schmiedeberg's Archives of Pharmacology, 2012 , vol. 385, # 7 p. 729 - 737 Title/Abstract Full Text View citing articles Show Details


5.94

EC50

1.16

µM

G-protein coupled receptor 35:Wild

HT-29

In Vitro (others)

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Deng, Huayun; Fang, Ye

Naunyn-Schmiedeberg's Archives of Pharmacology, 2012 , vol. 385, # 7 p. 729 - 737 Title/Abstract Full Text View citing articles Show Details

4.94

EC50

11.4

µM

G-protein coupled receptor 35:Wild

In Vitro (others)

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Deng, Huayun; Fang, Ye

Naunyn-Schmiedeberg's Archives of Pharmacology, 2012 , vol. 385, # 7 p. 729 - 737 Title/Abstract Full Text View citing articles Show Details

3.55

IC50

279.6

µM

platelet-rich plasma cell

In Vitro (others)

Pharmazie, 2010 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook

Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

=

-43

%

Inhibitor

Hematin [Plasmodium falciparum]:Wild

100 µg/mL

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Kurosawa; Dorn; Kitsuji-Shirane; Shimada; Satoh; Matile; Hofheinz; Masciadri; Kansy; Ridley

Antimicrobial Agents and Chemotherapy, 2000 , vol. 44, # 10 p. 2638 - 2644 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

300

µM

Anthrax toxin receptor 2:Mutated

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Cryan, Lorna M.; Bazinet, Lauren; Habeshian, Kaiane A.; Cao, Shugeng; Clardy, Jon; Christensen, Kenneth A.; Rogers, Michael S.

Journal of Medicinal Chemistry, 2013 , vol. 56, # 5 p. 1940 - 1945 Title/Abstract Full Text View citing articles Show Details

5

IC50

=

9.9

µM

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Teixeira, Jose; Silva, Tiago; Benfeito, Sofia; Gaspar, Alexandra; Garrido, E. Manuela; Garrido, Jorge; Borges, Fernanda

European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 289 - 296 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

45.9

%

Nitric oxide synthase, inducible:Wild

RAW 264.7 cell line

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas

Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details

3.2

IC50

=

631.6

µM

Nitric oxide synthase, inducible:Wild

RAW 264.7 cell line

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas

Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details

5.11

IC50

=

7.8

µM

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Teixeira, Jose; Silva, Tiago; Benfeito, Sofia; Gaspar, Alexandra; Garrido, E. Manuela; Garrido, Jorge; Borges, Fernanda

European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 289 - 296 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

32.4

%

Nitric oxide synthase, inducible:Wild

RAW 264.7 cell line

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details


Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas

Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

10.7

%

Nitric oxide synthase, inducible:Wild

RAW 264.7 cell line

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas

Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

31.7

%

Tyrosinase [mushroom]:Wild

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Vontzalidou, Argyro; Zoidis, Grigoris; Chaita, Eliza; Makropoulou, Maria; Aligiannis, Nektarios; Lambrinidis, George; Mikros, Emmanuel; Skaltsounis, Alexios-Leandros

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 17 p. 5523 - 5526 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

24.7

%

Nitric oxide synthase, inducible:Wild

RAW 264.7 cell line

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Schmid, Diethart; Gruber, Miriam; Piskaty, Carolin; Woehs, Florian; Renner, Andreas; Nagy, Zsofia; Kaltenboeck, Alexander; Wasserscheid, Thomas; Bazylko, Agnieszka; Kiss, Anna K.; Moeslinger, Thomas

Journal of Natural Products, 2012 , vol. 75, # 5 p. 870 - 875 Title/Abstract Full Text View citing articles Show Details

4.3

IC50

=

50

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Ni, Nanting; Choudhary, Gaurav; Li, Minyong; Wang, Binghe

Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 5 p. 1567 - 1572 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

22.5

%

BGC-823 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Chen, Zhuo; Liu, Yu-Mei; Yang, Song; Song, Bao-An; Xu, Guang-Fang; Bhadury, Pinaki S.; Jin, Lin-Hong; Hu, De-Yu; Liu, Fang; Xue, Wei; Zhou, Xia

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1337 - 1344 Title/Abstract Full Text View citing articles Show Details

5.2

IC50

=

0.00636

mM

Inhibitor

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Lopes, Thiago Inacio Barros; Coelho, Roberta Gomes; Yoshida, Nidia Cristiane; Honda, Neli Kika

Chemical and Pharmaceutical Bulletin, 2008 , vol. 56, # 11 p. 1551 - 1554 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

6.7

%

BGC-823 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Chen, Zhuo; Liu, Yu-Mei; Yang, Song; Song, Bao-An; Xu, Guang-Fang; Bhadury, Pinaki S.; Jin, Lin-Hong; Hu, De-Yu; Liu, Fang; Xue, Wei; Zhou, Xia

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1337 - 1344 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

16.7

%

BGC-823 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Chen, Zhuo; Liu, Yu-Mei; Yang, Song; Song, Bao-An; Xu, Guang-Fang; Bhadury, Pinaki S.; Jin, Lin-Hong; Hu, De-Yu; Liu, Fang; Xue, Wei; Zhou, Xia

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1337 - 1344 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

10.2

%

BGC-823 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Chen, Zhuo; Liu, Yu-Mei; Yang, Song; Song, Bao-An; Xu, Guang-Fang; Bhadury, Pinaki S.; Jin, Lin-Hong; Hu, De-Yu; Liu, Fang; Xue, Wei; Zhou, Xia

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1337 - 1344 Title/Abstract Full Text View citing articles Show Details


4.93

IC50

=

2

µg/mL

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila

Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details

2.89

IC50

=

220

µg/mL

Inhibitor

K-562 cell line

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila

Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details

%

=

85.6

%

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Tsao, Chuan-Chung; Shen, Yuh-Chiang; Su, Chung-Ren; Li, Chia-Ying; Liou, Meei-Jen; Dung, Nguyen-Xuan; Wu, Tian-Shung

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9867 - 9870 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

21.5

%

Inhibitor

NADPH oxidase [Mus musculus]:Wild

BV-2 cell line

= 50 µm

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Tsao, Chuan-Chung; Shen, Yuh-Chiang; Su, Chung-Ren; Li, Chia-Ying; Liou, Meei-Jen; Dung, Nguyen-Xuan; Wu, Tian-Shung

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9867 - 9870 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

50

µM

Inhibitor

Nitric oxide synthase, inducible [Mus musculus]:Wild

BV-2 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Tsao, Chuan-Chung; Shen, Yuh-Chiang; Su, Chung-Ren; Li, Chia-Ying; Liou, Meei-Jen; Dung, Nguyen-Xuan; Wu, Tian-Shung

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9867 - 9870 Title/Abstract Full Text View citing articles Show Details

3.8

IC50

=

26.9

µg/mL

Inhibitor

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Chethan; Dharmesh, Shylaja M.; Malleshi, Nagappa G.

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 23 p. 10085 - 10090 Title/Abstract Full Text View citing articles Show Details

3.24

IC50

=

97.3

µg/mL

Inhibitor

Aldose reductase [human]:Wild

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Chethan; Dharmesh, Shylaja M.; Malleshi, Nagappa G.

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 23 p. 10085 - 10090 Title/Abstract Full Text View citing articles Show Details

2.89

IC50

=

220

µg/mL

K-562 cell line

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila

Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details

%

=

0.75

%

K-562 cell line

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila

Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details


% Inhibition

=

72

%

K-562 cell line

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; Dijoux-Franca, Marie-Genevieve; Chekir-Ghedira, Leila

Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details

2.09

IC50

=

8115

µM

Inhibitor

Plasminogen activator inhibitor 1 [human]:Wild

Patent: WO2008/131047 ...

Title/Abstract Full Text Show Details

Plasminogen activator inhibitor 1 [human]:Wild

Patent: WO2008/131047 ...

Title/Abstract Full Text Show Details

Journal of Natural Produ...

Title/Abstract Full Text Show Details

Journal of natural produ...

Title/Abstract Full Text Show Details

Journal of natural produ...

Title/Abstract Full Text Show Details

THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Patent: WO2008/131047 A2, 2008 ; Title/Abstract Full Text Show Details

3.65

IC50

=

225.2

µM

Inhibitor

THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Patent: WO2008/131047 A2, 2008 ; Title/Abstract Full Text Show Details

1

ED50

NA

Liu; Pezzuto; Kinghorn

Journal of Natural Products (Lloydia), 1988 , vol. 51, # 3 p. 619 - 620 Title/Abstract Full Text Show Details

4.48

IC50

=

33

µM

KAZUKI SAITO; MAKOTO MATSUMOTO; TOSHIKAZU SEKINE; ISAMU MURAKOSHI; NAOKO MORISAKI; SHIGEO IWASAKI

Journal of natural products, 1989 , vol. 52, # 6 p. 1221 - 1221 Title/Abstract Full Text Show Details

4.72

IC50

=

19

µM

Inhibitor

KAZUKI SAITO; MAKOTO MATSUMOTO; TOSHIKAZU SEKINE; ISAMU MURAKOSHI; NAOKO MORISAKI; SHIGEO IWASAKI

Journal of natural products, 1989 , vol. 52, # 6 p. 1221 - 1221 Title/Abstract Full Text Show Details

5.39

ED50

=

0.7

µg/mL

P388 cell line

Journal of Natural Produ...

Title/Abstract Full Text Show Details

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Liu; Pezzuto; Kinghorn

Journal of Natural Products (Lloydia), 1988 , vol. 51, # 3 p. 619 - 620 Title/Abstract Full Text Show Details

% Inhibition

=

23.4

%

Sugimoto, Sachiko; Chi, Guihua; Kato, Yasuyo; Nakamura, Seikou; Matsuda, Hisashi; Yoshikawa, Masayuki

Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 3 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details

%

=

71.2

%

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Kaur, Gurpreet; Athar, Mohammad; Alam, M. Sarwar

Chemico-Biological Interactions, 2008 , vol. 171, # 3 p. 272 - 282 Title/Abstract Full Text View citing articles Show Details

%

=

76.2

%

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Kaur, Gurpreet; Athar, Mohammad; Alam, M. Sarwar

Chemico-Biological Interactions, 2008 , vol. 171, # 3 p. 272 - 282


Title/Abstract Full Text View citing articles Show Details

%

=

85.7

%

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Kaur, Gurpreet; Athar, Mohammad; Alam, M. Sarwar

Chemico-Biological Interactions, 2008 , vol. 171, # 3 p. 272 - 282 Title/Abstract Full Text View citing articles Show Details

%

=

63

%

Chemico-Biological Inter...

Title/Abstract Full Text View citing articles Show Details

Kaur, Gurpreet; Athar, Mohammad; Alam, M. Sarwar

Chemico-Biological Interactions, 2008 , vol. 171, # 3 p. 272 - 282 Title/Abstract Full Text View citing articles Show Details

Activity

=

33.9

µM

Antioxidant

Patent: WO2012/35406 A...

Title/Abstract Full Text Show Details

COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; UNIVERSITY OF CALCUTTA; BANDYOPADHYAY, Uday; PAL, Chinmay; BINDU, Samik; ADHIKARI, Susanta, Sekhar

Patent: WO2012/35406 A1, 2012 ; Title/Abstract Full Text Show Details

% Inhibition

=

62.87

%

Antioxidant

Letters in Drug Design a...

Title/Abstract Full Text View citing articles Show Details

Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati

Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

44

%

Antioxidant

Letters in Drug Design a...

Title/Abstract Full Text View citing articles Show Details

Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati

Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details

Activity

=

46.59

µM

Antioxidant

Patent: WO2012/35406 A...

Title/Abstract Full Text Show Details

COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; UNIVERSITY OF CALCUTTA; BANDYOPADHYAY, Uday; PAL, Chinmay; BINDU, Samik; ADHIKARI, Susanta, Sekhar

Patent: WO2012/35406 A1, 2012 ; Title/Abstract Full Text Show Details

% Inhibition

=

33.72

%

Antioxidant

Letters in Drug Design a...

Title/Abstract Full Text View citing articles Show Details

Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati

Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

50.3

%

Antioxidant

Letters in Drug Design a...

Title/Abstract Full Text View citing articles Show Details

Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati

Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details

5.08

IC50

=

1.4

µg/mL

radical scavenging

Journal of Enzyme Inhibi...

Title/Abstract Full Text View citing articles Show Details

Sasidharan, Indu; Sundaresan; Nisha; Kirishna, Mahesh S.; Raghu; Jayamurthy

Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 4 p. 578 - 586 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

58.1

%

Antioxidant

Letters in Drug Design a...

Title/Abstract Full Text View citing articles Show Details


Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati

Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

47.23

%

Antioxidant

Letters in Drug Design a...

Title/Abstract Full Text View citing articles Show Details

Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati

Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details

4.5

IC50

=

31.56

µM

Antioxidant

Letters in Drug Design a...

Title/Abstract Full Text View citing articles Show Details

Anchuri, Shyam Sunder; Thota, Sreekanth; Yerra, Rajeshwar; Dhulipala, Satyavati

Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 421 - 425 Title/Abstract Full Text View citing articles Show Details

5.92

IC50

=

1.2

µM

radical scavenging

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Odo, Junichi; Kimura, Ayumi; Matsu-Ura, Atsushi; Ohnishi, Yuki; Saeki, Yoshiro; Yoshida, Akiko; Hayashi, Ken-Ichiro; Inoguchi, Masahiko; Ueki, Takahiko

Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 12 p. 1576 - 1581 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

5000

µM

Glycoprotein 41 [Human immunodeficiency virus 1]:Wild

ChemMedChem, 2011 , vol...

Title/Abstract Full Text View citing articles Show Details

Liu, Yan; Ke, Zhuofeng; Wu, Kwok Yiu; Liu, Shuwen; Chen, Wen-Hua; Jiang, Shibo; Jiang, Zhi-Hong

ChemMedChem, 2011 , vol. 6, # 9 p. 1654 - 1664 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1000

µM

lipase [pig]:Wild

pancreas cell

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kato, Eisuke; Yama, Michitsugu; Nakagomi, Ryo; Shibata, Toshiro; Hosokawa, Keizo; Kawabata, Jun

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 20 p. 6410 - 6412 Title/Abstract Full Text View citing articles Show Details

IC50

ND

alpha-glucosidase [Saccharomyces cerevisiae]:Wild

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Wan, Chunpeng; Yuan, Tao; Li, Liya; Kandhi, Vamsikrishna; Cech, Nadja B.; Xie, Mingyong; Seeram, Navindra P.

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 597 - 600 Title/Abstract Full Text View citing articles Show Details

4.69

IC50

=

20.39

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Wan, Chunpeng; Yuan, Tao; Li, Liya; Kandhi, Vamsikrishna; Cech, Nadja B.; Xie, Mingyong; Seeram, Navindra P.

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 597 - 600 Title/Abstract Full Text View citing articles Show Details

4.53

IC50

=

5

µg/mL

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Gamez; Luyengi; Sang Kook Lee; Zhu; Zhou; Fong; Pezzuto; Kinghorn

Journal of Natural Products, 1998 , vol. 61, # 5 p. 706 - 708 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

µg/mL

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Cai, Lining; Wu, Christine D.

Journal of Natural Products, 1996 , vol. 59, # 10 p. 987 - 990


Title/Abstract Full Text View citing articles Show Details

5.38

EC50

=

4.2

µM

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Yasuda; Inaba; Ohmori; Endo; Kubo; Ohsawa

Journal of Natural Products, 2000 , vol. 63, # 10 p. 1444 - 1446 Title/Abstract Full Text View citing articles Show Details

%

=

86.8

%

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji

Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details

%

=

34.9

%

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji

Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details

3.04

MIC

=

156

µg/mL

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Cai, Lining; Wu, Christine D.

Journal of Natural Products, 1996 , vol. 59, # 10 p. 987 - 990 Title/Abstract Full Text View citing articles Show Details

4.66

IC50

=

21.8

µM

Inhibitor

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Park, Eun Jung; Kim, Youngleem; Kim, Jinwoong

Journal of Natural Products, 2000 , vol. 63, # 1 p. 34 - 36 Title/Abstract Full Text View citing articles Show Details

4.66

IC50

=

3.7

µg/mL

Inhibitor

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Park, Eun Jung; Kim, Youngleem; Kim, Jinwoong

Journal of Natural Products, 2000 , vol. 63, # 1 p. 34 - 36 Title/Abstract Full Text View citing articles Show Details

3.34

MIC

=

78

µg/mL

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Cai, Lining; Wu, Christine D.

Journal of Natural Products, 1996 , vol. 59, # 10 p. 987 - 990 Title/Abstract Full Text View citing articles Show Details

4.73

IC50

=

18.8

µM

HL-60 cell line

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Park, Eun Jung; Kim, Youngleem; Kim, Jinwoong

Journal of Natural Products, 2000 , vol. 63, # 1 p. 34 - 36 Title/Abstract Full Text View citing articles Show Details

4.73

IC50

=

3.2

µg/mL

HL-60 cell line

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Park, Eun Jung; Kim, Youngleem; Kim, Jinwoong

Journal of Natural Products, 2000 , vol. 63, # 1 p. 34 - 36 Title/Abstract Full Text View citing articles Show Details

%

=

61.6

%

Journal of Natural Produ...


Title/Abstract Full Text View citing articles Show Details

Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji

Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details

%

=

94.8

%

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji

Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details

%

=

95.7

%

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji

Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details

%

=

19

%

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Kikuzaki, Hiroe; Sato, Akemi; Mayahara, Yoko; Nakatani, Nobuji

Journal of Natural Products, 2000 , vol. 63, # 6 p. 749 - 752 Title/Abstract Full Text View citing articles Show Details

4.23

IC50

10

µg/mL

Inhibitor

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Westenburg; Lee; Fong; Van Breemen; Pezzuto; Kinghorn

Journal of Natural Products, 2000 , vol. 63, # 12 p. 1696 - 1698 Title/Abstract Full Text View citing articles Show Details

3.34

MIC

=

78

µg/mL

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Cai, Lining; Wu, Christine D.

Journal of Natural Products, 1996 , vol. 59, # 10 p. 987 - 990 Title/Abstract Full Text View citing articles Show Details

4.06

IC50

=

14.8

µg/mL

Inhibitor

erythrocyte

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Subeki; Matsuura, Hideyuki; Takahashi, Kosaku; Yamasaki, Masahiro; Yamato, Osamu; Maede, Yoshimitsu; Katakura, Ken; Kobayashi, Sumiko; Trimurningsih; Chairul; Yoshihara, Teruhiko

Journal of Natural Products, 2005 , vol. 68, # 4 p. 537 - 539 Title/Abstract Full Text View citing articles Show Details

Activity

=

8.08

µM

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Wada, Shun-Ichi; Yasui, Yumiko; Hitomi, Teppei; Tanaka, Reiko

Journal of Natural Products, 2007 , vol. 70, # 10 p. 1605 - 1610 Title/Abstract Full Text View citing articles Show Details

6.28

IC50

0.53

µM

Inhibitor

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Wada, Shun-Ichi; Yasui, Yumiko; Hitomi, Teppei; Tanaka, Reiko

Journal of Natural Products, 2007 , vol. 70, # 10 p. 1605 - 1610 Title/Abstract Full Text View citing articles Show Details

4.1

IC50

=

13.4

µg/mL

Inhibitor

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details


Subeki; Matsuura, Hideyuki; Takahashi, Kosaku; Yamasaki, Masahiro; Yamato, Osamu; Maede, Yoshimitsu; Katakura, Ken; Kobayashi, Sumiko; Trimurningsih; Chairul; Yoshihara, Teruhiko

Journal of Natural Products, 2005 , vol. 68, # 4 p. 537 - 539 Title/Abstract Full Text View citing articles Show Details

4.52

IC50

=

29.9

µM

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Nuntanakorn, Paiboon; Jiang, Bei; Einbond, Linda S.; Yang, Hui; Kronenberg, Fredi; Weinstein, I. Bernard; Kennelly, Edward J.

Journal of Natural Products, 2006 , vol. 69, # 3 p. 314 - 318 Title/Abstract Full Text View citing articles Show Details

4.52

IC50

=

30

µM

Inhibitor

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Reynertson, Kurt A.; Wallace, Alison M.; Adachi, Seiji; Gil, Roberte R.; Yang, Hui; Basile, Margaret J.; D'Armiento, Jeanine; Weinstein, I. Bernard; Kennelly, Edward J.

Journal of Natural Products, 2006 , vol. 69, # 8 p. 1228 - 1230 Title/Abstract Full Text View citing articles Show Details

5.57

IC50

2.7

µM

Inhibitor

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Su, Bao-Ning; Pawlus, Alison D.; Jung, Hyun-Ah; Keller, William J.; McLaughlin, Jerry L.; Kinghorn, A. Douglas

Journal of Natural Products, 2005 , vol. 68, # 4 p. 592 - 595 Title/Abstract Full Text View citing articles Show Details

4.72

GI50

=

19

µM

mK1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kinjo, Junei; Nagao, Tsuneatsu; Tanaka, Takashi; Nonaka, Gen-Ichiro; Okabe, Hikaru

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 12 p. 1443 - 1445 Title/Abstract Full Text View citing articles Show Details

2.5

MIC

=

533

µg/mL

Inhibitor

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

5.03

IC50

=

1.6

µg/mL

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter

Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details

4.84

GI50

=

14.4

µM

Inhibitor

Biological and pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo

Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details

2.71

MIC

=

333

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

3.11

MIC

=

133

µg/mL

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


3.53

MIC

=

50

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

30

µg/mL

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter

Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details

2.5

MIC

=

533

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.56

MIC

=

467

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.71

MIC

=

333

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

=

500

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

Activity

=

1.98

mM

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rastija, Vesna; Medic-Saric, Marica

European Journal of Medicinal Chemistry, 2009 , vol. 44, # 1 p. 400 - 408 Title/Abstract Full Text View citing articles Show Details

2.8

MIC

=

267

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

4.46

IC50

~

35

µM

Inhibitor

PLC/PRF/5 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Isuzugawa; Ogihara; Inoue

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details

4.66

GI50

=

22

µM

HeLa cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


Kinjo, Junei; Nagao, Tsuneatsu; Tanaka, Takashi; Nonaka, Gen-Ichiro; Okabe, Hikaru

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 12 p. 1443 - 1445 Title/Abstract Full Text View citing articles Show Details

2.45

MIC

=

600

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

3.4

MIC

=

67

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.8

MIC

=

267

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.5

MIC

=

533

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

Activity

=

4.1

µM

Biological and pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Yoshikawa, Masayuki; Ninomiya, Kiyofumi; Shimoda, Hiroshi; Nishida, Norihisa; Matsuda, Hisashi

Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 72 - 76 Title/Abstract Full Text View citing articles Show Details

2.41

MIC

=

667

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

4.07

IC50

=

14.4

µg/mL

Inhibitor

L6

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter

Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details

2.5

MIC

=

533

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.2

MIC

=

1067

µg/mL

Inhibitor

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235


Title/Abstract Full Text View citing articles Show Details

4.68

TGI

=

20.8

µM

Biological and pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo

Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details

4.46

IC50

~

35

µM

Inhibitor

HeLa cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Isuzugawa; Ogihara; Inoue

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details

5.15

GI50

=

7.1

µM

B16-F10 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kinjo, Junei; Nagao, Tsuneatsu; Tanaka, Takashi; Nonaka, Gen-Ichiro; Okabe, Hikaru

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 12 p. 1443 - 1445 Title/Abstract Full Text View citing articles Show Details

3.4

IC50

=

67

µg/mL

L6

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter

Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details

2.45

MIC

=

600

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

4.07

IC50

=

84.5

µM

Inhibitor

catechol Omethyltransferase [Rattus norvegicus]:Wild

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kadowaki, Masaaki; Ootani, Emi; Sugihara, Narumi; Furuno, Koji

Biological and Pharmaceutical Bulletin, 2005 , vol. 28, # 8 p. 1509 - 1513 Title/Abstract Full Text View citing articles Show Details

1

TGI

>

1000

µM

Biological and pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo

Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details

3.31

MIC

=

83

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

1

GI50

>

1000

µM

Inhibitor

Biological and pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo

Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details

4.46

IC50

~

35

µM

Inhibitor

DRLh-84

Biological and Pharmaceu...


cell line

Title/Abstract Full Text View citing articles Show Details

Isuzugawa; Ogihara; Inoue

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details

2.41

MIC

=

667

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

4.46

IC50

~

35

µM

Inhibitor

HL60RG cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Isuzugawa; Ogihara; Inoue

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details

2.03

MIC

=

1600

µg/mL

Inhibitor

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.63

MIC

=

400

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

=

500

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

4.46

IC50

~

35

µM

Inhibitor

KB

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Isuzugawa; Ogihara; Inoue

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 3 p. 249 - 253 Title/Abstract Full Text View citing articles Show Details

3.11

MIC

=

133

µg/mL

Inhibitor

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.5

MIC

=

533

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.03

MIC

=

1600

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

2.8

MIC

=

267

µg/mL

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Taguri, Toshitsugu; Tanaka, Takashi; Kouno, Isao

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 11 p. 2226 - 2235 Title/Abstract Full Text View citing articles Show Details

4.2

IC50

=

63

µM

Inhibitor

peritoneal macrophage

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kageura, Tadashi; Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Harima, Shoichi; Oda, Mamiko; Yoshikawa, Masayuki

Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 7 p. 1887 - 1893 Title/Abstract Full Text View citing articles Show Details

5.74

IC50

=

1.8

µM

Inhibitor

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki

Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

10

µM

Inhibitor

xanthine dehydrogenase:Wild

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki

Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details

% Inhibition

ND

Inhibitor

xanthine dehydrogenase:Wild

= 20 µm

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki

Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

0

%

Inhibitor

xanthine dehydrogenase:Wild

= 20 µm

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki

Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details

Activity

=

3.9

µM

Inhibitor

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Matsuda, Hisashi; Morikawa, Toshio; Toguchida, Iwao; Park, Ji-Young; Harima, Shoichi; Yoshikawa, Masayuki

Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 41 - 50 Title/Abstract Full Text View citing articles Show Details

Vmax

=

0

µM/min

Radioligand (/ligand)

Polyphenol oxidase, chloroplastic [Camellia sinensis]:Wild

Phytochemistry, 1973 , ...

Title/Abstract Full Text Show Details

Prostaglandin G/H synthase 2:Wild

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

PHILIP COGGON; GERALD A MOSS; GARY W SANDERSON

Phytochemistry, 1973 , vol. 12, # 8 p. 1947 - 1955 Title/Abstract Full Text Show Details

% Inhibition

>

30

%

Huss; Ringbom; Perera; Bohlin; Vasaenge

Journal of Natural Products, 2002 , vol. 65, # 11 p. 1517 - 1521 Title/Abstract Full Text View citing articles Show Details


Activity

0

Phytochemistry, 1971 , ...

Title/Abstract Full Text Show Details

Squalene monooxygenase [Rattus norvegicus]:Wild

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

P. V. SUBBA RAO; B. FRITIG; J. R. VOSE; G. H. N. TOWERS

Phytochemistry, 1971 , vol. 10, # 1 p. 51 - 56 Title/Abstract Full Text Show Details

4.14

IC50

=

73

µM

Inhibitor

Abe; Kashiwagi; Noguchi; Tanaka; Ikeshiro; Kashiwada

Journal of Natural Products, 2001 , vol. 64, # 8 p. 1010 - 1014 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

5000

ng/mL

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Verotta, Luisella; Dell'Agli, Mario; Giolito, Andrea; Guerrini, Marco; Cabalion, Pierre; Bosisio, Enrica

Journal of Natural Products, 2001 , vol. 64, # 5 p. 603 - 607 Title/Abstract Full Text View citing articles Show Details

4.75

IC50

=

17.6

µM

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Kyriakopoulou; Magiatis; Skaltsounis; Aligiannis; Harvala

Journal of Natural Products, 2001 , vol. 64, # 8 p. 1095 - 1097 Title/Abstract Full Text View citing articles Show Details

Polyphenol oxidase, chloroplastic [Camellia sinensis]:Wild

Phytochemistry, 1973 , ...

Title/Abstract Full Text Show Details

Polyphenol oxidase, chloroplastic [Camellia sinensis]:Wild

Phytochemistry, 1973 , ...

Title/Abstract Full Text Show Details

DNA topoisomerase 1 [taurine cattle]:Wild

thymus

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

PHILIP COGGON; GERALD A MOSS; GARY W SANDERSON

Phytochemistry, 1973 , vol. 12, # 8 p. 1947 - 1955 Title/Abstract Full Text Show Details

Km

=

0.8

M

PHILIP COGGON; GERALD A MOSS; GARY W SANDERSON

Phytochemistry, 1973 , vol. 12, # 8 p. 1947 - 1955 Title/Abstract Full Text Show Details

1

IC50

>

1000

mM

Inhibitor

Suzuki, Keitarou; Yahara, Shoji; Hashimoto, Fumio; Uyeda, Masaru

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 9 p. 1088 - 1090 Title/Abstract Full Text View citing articles Show Details

IC50

=

196

mM

Inhibitor

DNA topoisomerase 2 [human]:Wild

Placental cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Suzuki, Keitarou; Yahara, Shoji; Hashimoto, Fumio; Uyeda, Masaru

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 9 p. 1088 - 1090 Title/Abstract Full Text View citing articles Show Details

Activity

@

Inhibitor

Nuclear factor NFkappa-B p105 subunit [Escherichia coli]:Wild

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Sharma, Rakesh K.; Pande, Vineet; Ramos, Maria J.; Rajor, Hament K.; Chopra, Shilpa; Meguro, Kazuyuki; Inoue, Jun-Ichiro; Otsuka, Masami

Bioorganic Chemistry, 2005 , vol. 33, # 2 p. 67 - 81 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

8.2

%

Biochemical and Biophysi...

Title/Abstract Full Text View citing articles Show Details


Mizushina, Yoshiyuki; Saito, Akiko; Tanaka, Akira; Nakajima, Noriyuki; Kuriyama, Isoko; Takemura, Masaharu; Takeuchi, Toshifumi; Sugawara, Fumio; Yoshida, Hiromi

Biochemical and Biophysical Research Communications, 2005 , vol. 333, # 1 p. 101 - 109 Title/Abstract Full Text View citing articles Show Details

Activity

ND

hydroquinone glucosyltransferase [Escherichia coli]:Wild

Bioorganic and medicinal...

Title/Abstract Full Text Show Details

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Hefner, Tobias; Arend, Joachim; Warzecha, Heribert; Siems, Karsten; Stoeckigt, Joachim

Bioorganic and medicinal chemistry, 2002 , vol. 10, # 6 p. 1731 - 1741 Title/Abstract Full Text Show Details

MBC

ND

Inhibitor

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

MIC

ND

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

1

MBC

>

3200

µg/mL

Inhibitor

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

3200

µg/mL

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

MBC

ND

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

MBC

ND

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

1.73

MIC

=

3200

µg/mL

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

MBC

ND

Inhibitor

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details


MIC

ND

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

3200

µg/mL

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4255 - 4262 Title/Abstract Full Text View citing articles Show Details

%

=

133

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

%

=

133

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

3.69

Ki

=

0.206

mM

20S Proteasome [human]:Wild

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details

4.41

Ki

=

0.039

mM

20S Proteasome [human]:Wild

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details

Activity

=

3.52

M

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Perez-Garrido, Alfonso; Helguera, Aliuska Morales; Morillas Ruiz, Juana M.; Zafrilla Rentero, Pilar

European Journal of Medicinal Chemistry, 2012 , vol. 49, p. 86 - 94 Title/Abstract Full Text View citing articles Show Details

%

=

110

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

%

=

159

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

2.57

Ki

=

2.722

mM

20S Proteasome [human]:Wild

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details


Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details

%

=

155

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

%

=

162

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

%

=

119

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

3.83

Ki

=

0.148

mM

20S Proteasome [human]:Wild

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details

%

=

142

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

3.24

Ki

=

0.578

mM

20S Proteasome [human]:Wild

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details

4.6

Ki

=

0.025

mM

20S Proteasome [human]:Wild

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Lei, Meng; Liu, Yunde; Zhu, Yongqiang; Liu, Zhenming

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 23 p. 2931 - 2944 Title/Abstract Full Text View citing articles Show Details

%

=

118

%

Current Topics in Medici...

Title/Abstract Full Text View citing articles Show Details

Mahadeswaraswamy; Kumar; Gowtham, Yashonandana J.; Nagaraju; Girish; Kemparaju

Current Topics in Medicinal Chemistry, 2011 , vol. 11, # 20 p. 2520 - 2530 Title/Abstract Full Text View citing articles Show Details

EC50

=

11.72

M

Inhibitor

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Nadal, Brice; Thetiot-Laurent, Sophie A.-L.; Pin, Serge; Renault, Jean-Philippe; Cressier, Damien; Rima, Ghassoub; Le Roux, Antoine; Meunier, Stephane; Wagner, Alain; Lion, Claude; Le Gall, Thierry

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 22 p. 7931 - 7939


Title/Abstract Full Text View citing articles Show Details

1

Kid

NA

Protease [Human immunodeficiency virus 1]:Wild

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Flausino Jr.; Dufau; Regasini; Petrônio; Silva; Rose; Bolzani; Reboud-Ravaux

Current Medicinal Chemistry, 2012 , vol. 19, # 26 p. 4534 - 4540 Title/Abstract Full Text View citing articles Show Details

Activity

=

1.36

nM

Inhibitor

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Nadal, Brice; Thetiot-Laurent, Sophie A.-L.; Pin, Serge; Renault, Jean-Philippe; Cressier, Damien; Rima, Ghassoub; Le Roux, Antoine; Meunier, Stephane; Wagner, Alain; Lion, Claude; Le Gall, Thierry

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 22 p. 7931 - 7939 Title/Abstract Full Text View citing articles Show Details

Activity

1.78

Copper Ion Binding / Oxidoreductase [Escherichia coli]:Wild

Patent: WO2007/63614 A...

Title/Abstract Full Text Show Details

NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY; MANDOM Corporation; OTSUKA, Kaori; TSUJINO, Yoshio; KONNO, Yusuke; KUROSE, Shinji; KATAOKA, Kunishige; SAKURAI, Takeshi

Patent: WO2007/63614 A1, 2007 ; Title/Abstract Full Text Show Details

Activity

5.17

Copper Ion Binding / Oxidoreductase [Escherichia coli]:Wild

Patent: WO2007/63614 A...

Title/Abstract Full Text Show Details

NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY; MANDOM Corporation; OTSUKA, Kaori; TSUJINO, Yoshio; KONNO, Yusuke; KUROSE, Shinji; KATAOKA, Kunishige; SAKURAI, Takeshi

Patent: WO2007/63614 A1, 2007 ; Title/Abstract Full Text Show Details

Activity

=

93.4

%

Brain cortical neuron cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

58.3

%

Inhibitor

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

0

%

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

Activity

=

22.6

µmol/mg protein

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

2.92

µmol/mg protein

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details


Ratio

2.77

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

pX

Parameter

Value (qual)

Value (quant)

Unit

Activity

=

21.27

%

Action on Target

Target

Tissue/Organ

Cell

Bioassay

Dose

Effect

GMK-AH-1 cell line

Reference (expand all/collapse all) Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

Activity

=

27

%

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

22

%

Inhibitor

Tyrosinase [Mus musculus]:Wild

B16

= 50 µm

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

0

%

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

36.77

%

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

41.21

%

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

Activity

=

69.6

%

Brain cortical neuron cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details

Activity

=

15.2

%

Inhibitor

Brain cortical neuron cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details

Survival activity

=

59.7

%

B103 cell line

Biological and pharmaceu...

Title/Abstract Full Text Show Details

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Mook-Jung, Inhee; Kim, Hee; Fan, Wenzhe; Tezuka, Yasuhiro; Kadota, Shigetoshi; Nishijo, Hisao; Jung, Min Whan

Biological and pharmaceutical bulletin, 2002 , vol. 25, # 8 p. 1101 - 1104 Title/Abstract Full Text Show Details

1

CC50

>

1000

µM

Inhibitor

GMK-AH-1 cell line

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

Activity

=

0

%

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

33.9

%

Inhibitor

Tyrosinase [Mus musculus]:Wild

B16

= 25 µm

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

20.1

%

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

%

=

99.1

%

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

0

%

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

Activity

=

67.1

µmol/mg protein

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

42.5

µmol/mg protein

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

0

%

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

Activity

=

0.38

µM

Brain cortical neuron cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details

Ratio

19.1

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

%

=

90.6

%

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

4

IC50

=

0.0001

M

Inhibitor

aromatase [Rattus norvegicus]:Wild

ovary cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Satoh, Kanako; Nonaka, Rhouichi; Ishikawa, Fusako; Ogata, Akio; Nagai, Fumiko

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 3 p. 357 - 362 Title/Abstract Full Text View citing articles Show Details

5.44

IC50

=

3.59E06

M

Inhibitor

Tyrosinase [mushroom]:Wild

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

%

=

98.3

%

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

33.6

%

Inhibitor

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

84.7

%

Inhibitor

Brain cortical neuron cell

Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


% Inhibition

=

29.5

%

Inhibitor

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

4.47

IC50

=

33.56

µM

Inhibitor

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

4.19

IC50

=

64.35

µM

Inhibitor

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

Activity

=

0.6

µM

Brain cortical neuron cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

2.21

%

Inhibitor

Tyrosinase [Mus musculus]:Wild

B16

= 200 µm

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

71.5

%

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

4.88

IC50

=

13.16

µM

Inhibitor

GMK-AH-1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kratz, Jadel Mueller; Andrighetti-Froehner, Carla Regina; Leal, Paulo Cesar; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Trybala, Edward; Bergstroem, Tomas; Barardi, Celia Regina Monte; Simoes, Claudia Maria Oliveira

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 5 p. 903 - 907 Title/Abstract Full Text View citing articles Show Details

Ratio

33.6

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Inhibitor

aryl hydrocarbon receptor [mammal]:Wild

Amakura, Yoshiaki; Tsutsumi, Tomoaki; Sasaki, Kumiko; Yoshida, Takashi; Maitani, Tamio

Biological and Pharmaceutical Bulletin, 2003 , vol. 26, # 12 p. 1754 - 1760 Title/Abstract Full Text View citing articles Show Details

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


Activity

=

30

%

Inhibitor

Brain cortical neuron cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details

Activity

=

5.93

µmol/mg protein

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

39

%

Inhibitor

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

4.04

µmol/mg protein

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

21.4

%

Inhibitor

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Ratio

10.8

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

33.4

%

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

48.4

µM

Brain cortical neuron cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Ban, Ju Yeon; Nguyen, Ha Thi Thuy; Lee, Hee-Ju; Cho, Soon Ock; Ju, Hyun Soo; Kim, Ju Yeon; Bae, KiHwan; Song, Kyung-Sik; Seong, Yeon Hee

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 1 p. 149 - 153 Title/Abstract Full Text View citing articles Show Details

4.47

IC50

=

3.4E-05

M

Inhibitor

aromatase [Rattus norvegicus]:Wild

ovary cell

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Satoh, Kanako; Nonaka, Rhouichi; Ishikawa, Fusako; Ogata, Akio; Nagai, Fumiko

Biological and Pharmaceutical Bulletin, 2008 , vol. 31, # 3 p. 357 - 362 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

6.89

%

Inhibitor

Tyrosinase [Mus musculus]:Wild

B16

= 100 µm

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details


Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

96.2

µmol/mg protein

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

Activity

=

3.52

µmol/mg protein

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

42.6

%

Inhibitor

Tyrosinase [Mus musculus]:Wild

B16

= 10 µm

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

%

=

93.5

%

B16

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kim, You-Jung

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 6 p. 1052 - 1055 Title/Abstract Full Text View citing articles Show Details

%

=

79

%

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details

%

=

80

%

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details

4.17

ID50

=

11.6

µg/mL

Inhibitor

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Okuda; Kimura; Yoshida; Hatano; Arichi

Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631 Title/Abstract Full Text View citing articles Show Details

Activity

=

15.2

µeq/g

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details

3.95

ID50

=

19

µg/mL

Inhibitor

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Okuda; Kimura; Yoshida; Hatano; Arichi

Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631


Title/Abstract Full Text View citing articles Show Details

Activity

=

8.6

µeq/g

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

19

%

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Okuda; Kimura; Yoshida; Hatano; Arichi

Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631 Title/Abstract Full Text View citing articles Show Details

ZI

=

7

mm

Phytochemistry, 2005 , ...

Title/Abstract Full Text View citing articles Show Details

Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard

Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details

ZI

=

7

mm

Phytochemistry, 2005 , ...

Title/Abstract Full Text View citing articles Show Details

Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard

Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details

% Inhibition

40 - 50

%

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details

Activity

=

11.9

µeq/g

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

500

µM

Inhibitor

E-selectin [human]:Wild

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.

Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details

Activity

=

77

%

Phenylalanine ammonia-lyase [cucumber]:Wild

Phytochemistry, 1974 , ...

Title/Abstract Full Text Show Details

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

SUSAN E. IREDALE; HARRY SMITH

Phytochemistry, 1974 , vol. 13, # 3 p. 575 - 583 Title/Abstract Full Text Show Details

Activity

=

8.8

µeq/g

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details

%

=

59

%

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details


Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

50

%

Inhibitor

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Okuda; Kimura; Yoshida; Hatano; Arichi

Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631 Title/Abstract Full Text View citing articles Show Details

Activity

=

3.9

µM

Inhibitor

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Matsuda; Ohta; Kawaguchi; Yoshikawa

Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 1 p. 69 - 72 Title/Abstract Full Text View citing articles Show Details

Activity

=

8.7

µeq/g

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details

%

=

82

%

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

20

%

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Okuda; Kimura; Yoshida; Hatano; Arichi

Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1625 - 1631 Title/Abstract Full Text View citing articles Show Details

4.38

IC50

=

7.1

µg/mL

Inhibitor

xanthine dehydrogenase:Wild

Phytochemistry, 2005 , ...

Title/Abstract Full Text View citing articles Show Details

Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard

Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details

% Inhibition

ND

HL-60 cell line

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.

Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details

%

=

84

%

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506 Title/Abstract Full Text View citing articles Show Details

Activity

=

8.3

µeq/g

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2501 - 2506


Title/Abstract Full Text View citing articles Show Details

%

=

103

%

adipocyte

Chemical and pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Kimura; Okuda; Yoshida; Hatano; Arichi

Chemical and pharmaceutical bulletin, 1983 , vol. 31, # 7 p. 2497 - 2500 Title/Abstract Full Text View citing articles Show Details

% Inhibition

ND

HL-60 cell line

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.

Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details

ZI

=

7

mm

Phytochemistry, 2005 , ...

Title/Abstract Full Text View citing articles Show Details

Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard

Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details

ZI

=

13

mm

Phytochemistry, 2005 , ...

Title/Abstract Full Text View citing articles Show Details

Fogliani, Bruno; Raharivelomanana, Phila; Bianchini, Jean-Pierre; Bouraima-Madjebi, Saliou; Hnawia, Edouard

Phytochemistry, 2005 , vol. 66, # 2 p. 241 - 247 Title/Abstract Full Text View citing articles Show Details

4.72

IC50

=

19.1

µM

Inhibitor

P-selectin [human]:Wild

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.

Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details

4.56

IC50

=

27.6

µM

Inhibitor

L-selectin [human]:Wild

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Kranich, Remo; Busemann, Anke S.; Bock, Daniel; Schroeter-Maas, Sabine; Beyer, Diana; Heinemann, Bo; Meyer, Michael; Schierhorn, Katrin; Zahlten, Rainer; Wolff, Gerhard; Aydt, Ewald M.

Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1101 - 1115 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

33

%

Inhibitor

Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Fan; Tezuka; Ni; Kadota

Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 4 p. 396 - 401 Title/Abstract Full Text View citing articles Show Details

%

=

65

%

MDA-MB231

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Gomes, Catarina A.; Girao Da Cruz, Teresa; Andrade, Jose L.; Milhazes, Nuno; Borges, Fernanda; Marques, M. Paula M.

Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5395 - 5401 Title/Abstract Full Text View citing articles Show Details

%

=

50

%

MOLT-3 cell line

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Gomes, Catarina A.; Girao Da Cruz, Teresa; Andrade, Jose L.; Milhazes, Nuno; Borges, Fernanda; Marques, M. Paula M.

Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5395 - 5401 Title/Abstract Full Text View citing articles Show Details

%

=

74

%

HeLa cell

Journal of Medicinal Che...


line

Title/Abstract Full Text View citing articles Show Details

Gomes, Catarina A.; Girao Da Cruz, Teresa; Andrade, Jose L.; Milhazes, Nuno; Borges, Fernanda; Marques, M. Paula M.

Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5395 - 5401 Title/Abstract Full Text View citing articles Show Details

4.43

IC50

=

6.3

µg/mL

Antioxidant

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Yoshimura, Morio; Yamakami, Saori; Amakura, Yoshiaki; Yoshida, Takashi

Journal of Natural Products, 2012 , vol. 75, # 10 p. 1798 - 1802 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

50

µM

Inhibitor

Pancreatic triacylglycerol lipase:Wild

Patent: WO2006/22227 A...

Title/Abstract Full Text Show Details

%

Inhibitor

DIIodophenylpyruvate Reductase [taurine cattle]:Wild

heart

The Journal of biologica...

Title/Abstract Full Text View citing articles Show Details

SUNTORY LIMITED

Patent: WO2006/22227 A1, 2006 ; Title/Abstract Full Text Show Details

% Inhibition

<

5

Zannoni; Weber

The Journal of biological chemistry, 1966 , vol. 241, # 6 p. 1340 - 1344 Title/Abstract Full Text View citing articles Show Details

3.13

MIC

=

125

µg/mL

Letters in Applied Micro...

Title/Abstract Full Text Show Details

Archives of Biochemistry...

Title/Abstract Full Text View citing articles Show Details

Bisignano; Sanogo; Marino; Aquino; D'Angelo; Germano; De Pasquale; Pizza

Letters in Applied Microbiology, 2000 , vol. 30, # 2 p. 105 - 108 Title/Abstract Full Text Show Details

1

IC50

>

0.25

mM

Ueda, Jun-Ichi; Saito, Natuko; Shimazu, Yoshie; Ozawa, Toshihiko

Archives of Biochemistry and Biophysics, 1996 , vol. 333, # 2 p. 377 - 384 Title/Abstract Full Text View citing articles Show Details

4

ID50

=

100

µM

Ribonucleosidediphosphate reductase [Rattus norvegicus]:Wild

NOVIKOFF HEPATOMA CELL LINE

Cancer Research, 1979 , ...

Title/Abstract Full Text Show Details

Reverse transcriptase [Human immunodeficiency virus 1]:Wild

AIDS Research and Human ...

Title/Abstract Full Text Show Details

Letters in Applied Micro...

Title/Abstract Full Text Show Details

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Elford; Wampler; Van 'T Riet

Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details

1

ID50

>

588

µM

Ogata; Higuchi; Mochida; Matsumoto; Kato; Endo; Kaji

AIDS Research and Human Retroviruses, 1992 , vol. 8, # 11 p. 1937 - 1944 Title/Abstract Full Text Show Details

4.64

MIC

=

3.9

µg/mL

Bisignano; Sanogo; Marino; Aquino; D'Angelo; Germano; De Pasquale; Pizza

Letters in Applied Microbiology, 2000 , vol. 30, # 2 p. 105 - 108 Title/Abstract Full Text Show Details

MIC

ND

Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais

Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details


1

MIC

>

100

µg/mL

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais

Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details

4.64

MIC

=

3.9

µg/mL

Letters in Applied Micro...

Title/Abstract Full Text Show Details

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Bisignano; Sanogo; Marino; Aquino; D'Angelo; Germano; De Pasquale; Pizza

Letters in Applied Microbiology, 2000 , vol. 30, # 2 p. 105 - 108 Title/Abstract Full Text Show Details

MIC

ND

Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais

Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details

MIC

ND

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais

Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

Inhibitor

Poly(ADP-ribose) glycohydrolase [Mus musculus]:Wild

34i cell line

Journal of Biological Ch...

Title/Abstract Full Text Show Details

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Tsai; Aoki; Maruta; Abe; Sakagami; Hatano; Okuda; Tanuma

Journal of Biological Chemistry, 1992 , vol. 267, # 20 p. 14436 - 14442 Title/Abstract Full Text Show Details

3.53

MIC

=

50

µg/mL

Adesina; Idowu; Ogundaini; Oladimeji; Olugbade; Onawunmi; Pais

Phytotherapy Research, 2000 , vol. 14, # 5 p. 371 - 374 Title/Abstract Full Text View citing articles Show Details

3.13

MIC

=

125

µg/mL

Letters in Applied Micro...

Title/Abstract Full Text Show Details

Bisignano; Sanogo; Marino; Aquino; D'Angelo; Germano; De Pasquale; Pizza

Letters in Applied Microbiology, 2000 , vol. 30, # 2 p. 105 - 108 Title/Abstract Full Text Show Details

Inhibition Score

5

Ribonucleosidediphosphate reductase [Rattus norvegicus]:Wild

NOVIKOFF HEPATOMA CELL LINE

Cancer Research, 1979 , ...

Title/Abstract Full Text Show Details

Archives of Biochemistry...

Title/Abstract Full Text View citing articles Show Details

Elford; Wampler; Van 'T Riet

Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details

1

IC50

>

0.1

mM

Ueda, Jun-Ichi; Saito, Natuko; Shimazu, Yoshie; Ozawa, Toshihiko

Archives of Biochemistry and Biophysics, 1996 , vol. 333, # 2 p. 377 - 384 Title/Abstract Full Text View citing articles Show Details

Activity

=

0

%

Current medicinal chemis...

Title/Abstract Full Text Show Details

Mehta, Rajendra G; Naithani, Rajesh; Huma, Loredana; Hawthorne, Michael; Moriarty, Robert M; McCormick, David L; Steele, Vernon E; Kopelovich, Levy


Current medicinal chemistry, 2008 , vol. 15, # 27 p. 2785 - 2825 Title/Abstract Full Text Show Details

3.4

pGI50

3.4

Inhibitor

MEL

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

3.3

pGI50

3.3

Inhibitor

cancer cell line

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

3.5

pGI50

3.5

Inhibitor

OVCAR cell line

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

3.3

pGI50

3.3

Inhibitor

small cell lung cancer cell line

leukemia cell line

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

3.4

pGI50

3.4

Inhibitor

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

3.5

pGI50

3.5

Inhibitor

lung nonsmall cell carcinoma cell line

RENAL CANCER CELL LINE

CNS CANCER CELL LINE

PROSTATE CANCER CELL LINE

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

3.5

pGI50

3.5

Inhibitor

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

3.4

pGI50

3.4

Inhibitor

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

3.3

pGI50

3.3

Inhibitor

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details


% Inhibition

=

50

%

Inhibitor

Estradiol 17-betadehydrogenase 2 [human]:Wild

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Poirier, Donald

Current Medicinal Chemistry, 2003 , vol. 10, # 6 p. 453 - 477 Title/Abstract Full Text View citing articles Show Details

3.4

pGI50

3.4

Inhibitor

breast cancer cell line

Current Pharmaceutical D...

Title/Abstract Full Text View citing articles Show Details

Ren, Steven S.; Lien, Eric J.

Current Pharmaceutical Design, 2004 , vol. 10, # 12 p. 1399 - 1415 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

50

%

Inhibitor

Estradiol 17-betadehydrogenase 2:Wild

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Poirier, Donald

Current Medicinal Chemistry, 2003 , vol. 10, # 6 p. 453 - 477 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

Inhibitor

Tyrosinase [mushroom]:Wild

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Chen, Lih-Geeng; Chang, Wei-Ling; Lee, Chia-Jung; Lee, Lain-Tze; Shih, Chwen-Ming; Wang, Ching-Chiung

Biological and Pharmaceutical Bulletin, 2009 , vol. 32, # 8 p. 1447 - 1452 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

6.26

%

Inhibitor

Tyrosinase [mushroom]:Wild

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Chen, Lih-Geeng; Chang, Wei-Ling; Lee, Chia-Jung; Lee, Lain-Tze; Shih, Chwen-Ming; Wang, Ching-Chiung

Biological and Pharmaceutical Bulletin, 2009 , vol. 32, # 8 p. 1447 - 1452 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details


Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

4

MIC

=

100

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

4

MIC

100

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

3.9

MIC

=

125

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Leal; Mascarello; Derita; Zuljan; Nunes; Zacchino; Yunes

Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1793 - 1796 Title/Abstract Full Text View citing articles Show Details

6.15

EC50

=

0.7

µM

trachea

Medicinal Research Revie...

Title/Abstract Full Text View citing articles Show Details

Calixto, Joao B.; Santos, Adair R. S.; Cechinel Filho, Valdir; Yunes, Rosendo A.

Medicinal Research Reviews, 1998 , vol. 18, # 4 p. 225 - 258 Title/Abstract Full Text View citing articles Show Details

Activity

=

3

mM

Inhibitor

Signal Transducer And Activator Of Transcription 1, 91kDa:Wild

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Carcereri de Prati, Alessandra; Ciampa, Anna Rosa; Cavalieri, Elisabetta; Zaffini, Raffaela; Darra, Elena; Menegazzi, Marta; Suzuki, Hisanori; Mariotto, Sofia

Current Medicinal Chemistry, 2005 , vol. 12, # 16 p. 1819 - 1828 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

18.79

%

Cytochrome P450 2E1 [human]:Wild

NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho

Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details

Patent: WO2010/9572 A1...

Title/Abstract Full Text Show Details


Activity

9.62

radical scavenging

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

%

=

92.1

%

thrombocyte

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

%

=

91.9

%

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

Concentration

=

55.4

µM

Antioxidant

Pharmaceutical Chemistry...

Title/Abstract Full Text View citing articles Show Details

Agadzhanyan; Oganesyan; Abaev

Pharmaceutical Chemistry Journal, 2010 , vol. 44, # 7 p. 360 - 365 Title/Abstract Full Text View citing articles Show Details

Tlag

=

0.018

minute

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

10.5

%

Cytochrome P450 2E1 [human]:Wild

Patent: WO2010/9572 A1...

Title/Abstract Full Text Show Details

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho

Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details

Tlag

=

0.012

minute

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

%

=

90.6

%

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

%

=

88.5

%

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

35.59

%

Cytochrome P450 2E1 [human]:Wild

NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho

Patent: WO2010/9572 A1...

Title/Abstract Full Text Show Details


Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details

Activity

ND

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Yanovsky, Inessa; Finkin-Groner, Efrat; Zaikin, Andrey; Lerman, Lena; Shalom, Hila; Zeeli, Shani; Weill, Tehilla; Ginsburg, Isaac; Nudelman, Abraham; Weinstock, Marta

Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10700 - 10715 Title/Abstract Full Text View citing articles Show Details

Tlag

=

0.012

minute

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

Activity

=

31.4

%

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Yanovsky, Inessa; Finkin-Groner, Efrat; Zaikin, Andrey; Lerman, Lena; Shalom, Hila; Zeeli, Shani; Weill, Tehilla; Ginsburg, Isaac; Nudelman, Abraham; Weinstock, Marta

Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10700 - 10715 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

48.24

%

Cytochrome P450 2E1 [human]:Wild

Patent: WO2010/9572 A1...

Title/Abstract Full Text Show Details

Patent: WO2010/9572 A1...

Title/Abstract Full Text Show Details

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho

Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details

% Inhibition

=

42.74

%

Cytochrome P450 2E1 [human]:Wild

NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho

Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details

%

=

84.8

%

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

%

=

93.7

%

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

27.96

%

Cytochrome P450 2E1 [human]:Wild

Patent: WO2010/9572 A1...

Title/Abstract Full Text Show Details

scavenging

Phytochemistry, 2012 , ...

Title/Abstract Full Text View citing articles Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FUNDATION; HU, Yoapu Oliver; YOUNG, Tonho

Patent: WO2010/9572 A1, 2010 ; Title/Abstract Full Text Show Details

EC1

=

170

µM

Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.

Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details

%

=

81.5

%

thrombocyte

Antithrombotic

Bioorganic Chemistry, 20...

Title/Abstract Full Text View citing articles Show Details


Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

2.95

IC50

1.12

mM

scavenging

Phytochemistry, 2012 , ...

Title/Abstract Full Text View citing articles Show Details

Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.

Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details

%

=

56

%

scavenging

Phytochemistry, 2012 , ...

Title/Abstract Full Text View citing articles Show Details

Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.

Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details

5.49

IC50

=

3.24

µM

scavenging

Phytochemistry, 2012 , ...

Title/Abstract Full Text View citing articles Show Details

Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.

Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details

3.66

IC50

~

216.6

µM

Inhibitor

MCF7

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Sharma, Anupama; Gautam, Surya Prakash; Gupta, Arun Kumar

Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 11 p. 3341 - 3346 Title/Abstract Full Text View citing articles Show Details

IC50

=

75.4

µg

Inhibitor

hydrogen:potassiumexchanging ATPase:Wild

Patent: WO2007/113855 ...

Title/Abstract Full Text Show Details

Carbonic anhydrase 6 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH

Patent: WO2007/113855 A1, 2007 ; Title/Abstract Full Text Show Details

5.21

Ki

=

6.13

µM

Inhibitor

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

5.16

Ki

=

6.99

µM

Inhibitor

Carbonic anhydrase 9 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

6

%

Inhibitor

hydrogen:potassiumexchanging ATPase:Wild

Patent: WO2007/113855 ...

Title/Abstract Full Text Show Details

THP-1 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH

Patent: WO2007/113855 A1, 2007 ; Title/Abstract Full Text Show Details

Activity

ND

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details


5.65

Ki

=

2.25

µM

Inhibitor

Carbonic anhydrase 2 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

%

=

18.23

%

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

5.01

Ki

=

9.86

µM

Inhibitor

Carbonic anhydrase 13 [Mus musculus]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

5.22

Ki

=

6.07

µM

Inhibitor

Carbonic anhydrase 7 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

%

=

90.83

%

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

5.01

Ki

=

9.8

µM

Inhibitor

Carbonic anhydrase 4 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

Activity

ND

THP-1 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

%

=

38.42

%

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

5

Ki

=

9.97

µM

Inhibitor

Carbonic anhydrase 5B, mitochondrial [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

5.15

Ki

=

7.03

µM

Inhibitor

Carbonic anhydrase 14 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details


Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

5.13

Ki

=

7.49

µM

Inhibitor

Carbonic anhydrase 3 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

%

=

22.68

%

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

%

=

46.9

%

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

IC50

=

1.12

µg

Inhibitor

hydrogen:potassiumexchanging ATPase:Wild

Patent: WO2007/113855 ...

Title/Abstract Full Text Show Details

THP-1 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH

Patent: WO2007/113855 A1, 2007 ; Title/Abstract Full Text Show Details

Activity

ND

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

5.39

Ki

=

4.08

µM

Inhibitor

Carbonic anhydrase 5 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

%

=

19.45

%

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

5.49

Ki

=

3.2

µM

Inhibitor

Carbonic anhydrase 1 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details

5.11

Ki

=

7.78

µM

Inhibitor

Carbonic anhydrase 12 [human]:Wild

= 10 mM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Innocenti, Alessio; Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 6 p. 2159 - 2164 Title/Abstract Full Text View citing articles Show Details


pID50

-1.48

Farmaco, 2000 , vol. 55...

Title/Abstract Full Text View citing articles Show Details

Krogh; Yunes; Andricopulo

Farmaco, 2000 , vol. 55, # 11-12 p. 730 - 735 Title/Abstract Full Text View citing articles Show Details

ID50

=

30.4

µM/kg

Farmaco, 2000 , vol. 55...

Title/Abstract Full Text View citing articles Show Details

Krogh; Yunes; Andricopulo

Farmaco, 2000 , vol. 55, # 11-12 p. 730 - 735 Title/Abstract Full Text View citing articles Show Details

4.2

IC50

=

63

µM

Inhibitor

peritoneal macrophage

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Matsuda, Hisashi; Kageura, Tadashi; Morikawa, Toshio; Toguchida, Iwao; Harima, Shoichi; Yoshikawa, Masayuki

Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 4 p. 323 - 327 Title/Abstract Full Text View citing articles Show Details

1

Cytotoxic Score

NA

peritoneal macrophage

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Matsuda, Hisashi; Kageura, Tadashi; Morikawa, Toshio; Toguchida, Iwao; Harima, Shoichi; Yoshikawa, Masayuki

Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 4 p. 323 - 327 Title/Abstract Full Text View citing articles Show Details

5.81

IC50

=

1.55

µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Gupta, Sunil; Matthew, Susan; Abreu, Pedro M.; Aires-De-Sousa, Joao

Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 4 p. 1199 - 1206 Title/Abstract Full Text View citing articles Show Details

ED50

=

18.9

mg/kg bw

Journal of Biological Ch...

Title/Abstract Full Text View citing articles Show Details

Pal, Chinmay; Bindu, Samik; Dey, Sumanta; Alam, Athar; Goyal, Manish; Iqbal, Mohd Shameel; Sarkar, Souvik; Kumar, Rahul; Halder, Kamal Krishna; Debnath, Mita Chatterjee; Adhikari, Susanta; Bandyopadhyay, Uday

Journal of Biological Chemistry, 2012 , vol. 287, # 5 p. 3495 - 3509 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1

mM

Inhibitor

Alpha-amylase [human]:Wild

Patent: US5318986 A1, ...

Title/Abstract Full Text Show Details

µM

Inhibitor

Nuclear factor NFkappa-B p105 subunit:Wild

ChemMedChem, 2009 , vol...

Title/Abstract Full Text View citing articles Show Details

Mitsui Norin Co., Ltd.

Patent: US5318986 A1, 1994 ; Title/Abstract Full Text Show Details

4

IC50

100 200

Piccagli, Laura; Fabbri, Enrica; Borgatti, Monica; Bianchi, Nicoletta; Bezzerri, Valentino; Mancini, Irene; Nicolis, Elena; Dechecchi, Cristina M.; Lampronti, Ilaria; Cabrini, Giulio; Gambari, Roberto

ChemMedChem, 2009 , vol. 4, # 12 p. 2024 - 2033 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1

mM

Inhibitor

Nuclear factor NFkappa-B p105 subunit:Wild

ChemMedChem, 2009 , vol...

Title/Abstract Full Text View citing articles Show Details

Piccagli, Laura; Fabbri, Enrica; Borgatti, Monica; Bianchi, Nicoletta; Bezzerri, Valentino; Mancini, Irene; Nicolis, Elena; Dechecchi, Cristina M.; Lampronti, Ilaria; Cabrini, Giulio; Gambari, Roberto

ChemMedChem, 2009 , vol. 4, # 12 p. 2024 - 2033 Title/Abstract Full Text View citing articles Show Details

%

ND

radical scavenging

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details


Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni

Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details

%

=

97.14

%

radical scavenging

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni

Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details

5.74

IC50

=

1.83

µM

radical scavenging

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni

Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details

5.22

IC50

=

6

µM

radical scavenging

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni

Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details

3.31

IC50

=

487

µM

Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild

Nuclear factor NFkappa-B p105 subunit:Wild

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Orhan, I. Erdogan

Current Medicinal Chemistry, 2012 , vol. 19, # 14 p. 2252 - 2261 Title/Abstract Full Text View citing articles Show Details

3.3

IC50

<C

500

µM

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Cabrini; Bezzerri; Mancini; Nicolis; Dechecchi; Tamanini; Lampronti; Piccagli; Bianchi; Borgatti; Gambari

Current Medicinal Chemistry, 2010 , vol. 17, # 35 p. 4392 - 4404 Title/Abstract Full Text View citing articles Show Details

%

ND

radical scavenging

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Carocci, Alessia; Catalano, Alessia; Bruno, Claudio; Lovece, Angelo; Roselli, Maria Grazia; Cavalluzzi, Maria Maddalena; De Santis, Francesco; De Palma, Annalisa; Rusciano, Maria Rosaria; Illario, Maddalena; Franchini, Carlo; Lentini, Giovanni

Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 847 - 851 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

Inhibitor

Reverse transcriptase [Human immunodeficiency virus 1]:Mutated

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Tillekeratne; Sherette; Grossman; Hupe; Hudson

Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 20 p. 2763 - 2767 Title/Abstract Full Text View citing articles Show Details

IC50

ND

Inhibitor

RNA-directed DNA polymerase:Mutated

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Tillekeratne; Sherette; Grossman; Hupe; Hudson

Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 20 p. 2763 - 2767 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

Inhibitor

RNA-directed DNA polymerase:Mutated

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details


Tillekeratne; Sherette; Grossman; Hupe; Hudson

Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 20 p. 2763 - 2767 Title/Abstract Full Text View citing articles Show Details

%

=

41

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

Mini-Reviews in Medicina...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

%

=

88.9

%

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

5.39

EC50

=

4.1

µM

Matkowski, Adam; Kus, Piotr; Goralska, Edyta; Wozniak, Dorota

Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 439 - 455 Title/Abstract Full Text View citing articles Show Details

pX

Parameter

Value (qual)

IC50

ND

Value (quant)

Unit

Action on Target

Target

Tissue/Organ

Cell

Bioassay

Dose

Effect

Carbonic anhydrase 2 [human]:Wild

Reference (expand all/collapse all) Mini-Reviews in Medicina...

Title/Abstract Full Text View citing articles Show Details

Guelcin, Ilhami; Beydemir, Suekrue

Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 408 - 430 Title/Abstract Full Text View citing articles Show Details

3.41

IC50

=

387

µM

PLC/PRF/5 cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

IR-K562 cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

L929

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Antineoplastic

European Journal of Medi...

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

5.32

IC50

=

4.75

µM

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

3.6

IC50

=

250

µM

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

%

=

21.4

%

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

3.45

IC50

=

358

µM

HeLa cell


line

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

51

%

U-251MG cell line

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

RAW 264.7 cell line

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Yang, Zhi-Gang; Wen, Xiu-Feng; Li, Yong-Hai; Matsuzaki, Keiichi; Kitanaka, Susumu

Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 3 p. 279 - 285 Title/Abstract Full Text View citing articles Show Details

3.44

IC50

=

364

µM

DRLh-84 cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

%

=

34.4

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

%

=

73.6

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

5

IC50

10 - 50

µM

Calu-6 cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

%

=

21.4

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

4.4

IC50

=

40

µM

WEHI-231 cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

%

=

89.1

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details


Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

%

=

89.1

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

29

%

U-87

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

%

=

13.9

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

%

=

28

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

31

%

U-251MG cell line

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

5.12

IC50

=

1.28

µg/mL

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

4

IC50

100 200

µM

A-549

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

IC50

ND

Carbonic anhydrase 1 [human]:Wild

Mini-Reviews in Medicina...

Title/Abstract Full Text View citing articles Show Details

Guelcin, Ilhami; Beydemir, Suekrue

Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 408 - 430 Title/Abstract Full Text View citing articles Show Details

3.55

IC50

=

282

µM

P388D1 cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details


3.52

IC50

300

µM

HL-60 cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

30

%

U-87

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

3.5

IC50

=

317

µM

HL60RG cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

%

=

15.8

%

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Shakil; Singh, Manish K.; Sathiyendiran; Kumar; Padaria, Jasdeep C.

European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 120 - 131 Title/Abstract Full Text View citing articles Show Details

4.48

IC50

=

33

µM

K-562 cell line

Antineoplastic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

2.98

Ki

=

1.052

mM

Inhibitor

Carbonic anhydrase 1 [human]:Wild

erythrocyte

Chemical Biology and Dru...

Title/Abstract Full Text View citing articles Show Details

Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Chemical Biology and Drug Design, 2010 , vol. 75, # 5 p. 515 - 520 Title/Abstract Full Text View citing articles Show Details

3.12

Ki

=

0.758

mM

Inhibitor

Carbonic anhydrase 2 [human]:Wild

erythrocyte

Chemical Biology and Dru...

Title/Abstract Full Text View citing articles Show Details

Beyza Oeztuerk Sarikaya; Guelcin, Ilhami; Supuran, Claudiu T.

Chemical Biology and Drug Design, 2010 , vol. 75, # 5 p. 515 - 520 Title/Abstract Full Text View citing articles Show Details

4.38

IC50

=

41.8

µM

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kanno, Syu-Ichi; Kakuta, Mai; Kitajima, Yasue; Osanai, Yuu; Kurauchi, Kaori; Ohtake, Takaharu; Ujibe, Mayuko; Uwai, Kouji; Takeshita, Mitsuhiro; Ishikawa, Masaaki

Biological and Pharmaceutical Bulletin, 2007 , vol. 30, # 5 p. 994 - 998 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

Inhibitor

NS3 Protease [Hepatitis C virus]:Wild

Antiviral Research, 2007...

Title/Abstract Full Text View citing articles Show Details

Zuo, Guoying; Li, Zhengquan; Chen, Lirong; Xu, Xiaojie

Antiviral Research, 2007 , vol. 76, # 1 p. 86 - 92 Title/Abstract Full Text View citing articles Show Details

2.77

IC50

=

1710

µM

Inhibitor

NS3 Protease [Hepatitis C virus]:Wild

Antiviral Research, 2007...

Title/Abstract Full Text View citing articles Show Details


Zuo, Guoying; Li, Zhengquan; Chen, Lirong; Xu, Xiaojie

Antiviral Research, 2007 , vol. 76, # 1 p. 86 - 92 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

50

µM

Inhibitor

L1210 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details

4.74

IC50

=

18.3

µM

Inhibitor

HL-60 cell line

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

Murias, Marek; Jaeger, Walter; Handler, Norbert; Erker, Thomas; Horvath, Zsuzsanna; Szekeres, Thomas; Nohl, Hans; Gille, Lars

Biochemical Pharmacology, 2005 , vol. 69, # 6 p. 903 - 912 Title/Abstract Full Text View citing articles Show Details

%

=

90

%

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details

4.3

IC50

=

50

µM

Inhibitor

L1210 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

60.5

%

Inhibitor

arachidonate 15-lipoxygenase [soybean]:Wild

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Russell, Wendy R.; Scobbie, Lorraine; Duthie, Garry G.; Chesson, Andrew

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 8 p. 4589 - 4593 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

50

µM

Inhibitor

CCRF-CEM cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

50

µM

Inhibitor

CCRF-CEM cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details

3.39

IC50

=

68.52

µg/mL

Inhibitor

NIH-3T3

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Seung, Chul Lee; Yong, Soo Kwon; Kyung, Hun Son; Hyun, Pyo Kim; Moon, Young Heo

Archives of Pharmacal Research, 2005 , vol. 28, # 7 p. 775 - 783 Title/Abstract Full Text View citing articles Show Details

5.34

IC50

=

0.78

µg/mL

NIH-3T3

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Seung, Chul Lee; Yong, Soo Kwon; Kyung, Hun Son; Hyun, Pyo Kim; Moon, Young Heo

Archives of Pharmacal Research, 2005 , vol. 28, # 7 p. 775 - 783


Title/Abstract Full Text View citing articles Show Details

3.39

IC50

=

69.18

µg/mL

NIH-3T3

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Seung, Chul Lee; Yong, Soo Kwon; Kyung, Hun Son; Hyun, Pyo Kim; Moon, Young Heo

Archives of Pharmacal Research, 2005 , vol. 28, # 7 p. 775 - 783 Title/Abstract Full Text View citing articles Show Details

% Inhibition

77 - 100

%

Matrix metalloproteinase14:Wild

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

% Inhibition

34 - 76

%

Matrix metalloproteinase9:Wild

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

4.43

IC50

=

37

µM

Neutrophil collagenase:Wild

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

% Inhibition

77 - 100

%

72kDa type IV collagenase:Wild

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

4.3

IC50

=

50

µM

Matrix metalloproteinase14:Wild

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

% Inhibition

34 - 76

%

Neutrophil collagenase:Wild

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

4.64

IC50

=

23

µM

Matrix metalloproteinase9:Wild

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

5.62

IC50

=

2.4

µM

72kDa type IV collagenase:Wild

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

Activation

1.3

Peroxisome proliferator-

CV-1 cell

Patent: US2009/176810 ...


activated receptor alpha [Cercopithecidae]:Wild

line

Title/Abstract Full Text Show Details

AMOREPACIFIC Corporation

Patent: US2009/176810 A1, 2009 ; Title/Abstract Full Text Show Details

Activation

1.7

Peroxisome proliferatoractivated receptor alpha [Cercopithecidae]:Wild

CV-1 cell line

Patent: US2009/176810 ...

Title/Abstract Full Text Show Details

%

Inhibitor

Cytochrome P450 3A1 [Rattus norvegicus]:Wild

Patent: US2003/166584 ...

Title/Abstract Full Text Show Details

Patent: US2003/166584 ...

Title/Abstract Full Text Show Details

Patent: US2006/69042 A...

Title/Abstract Full Text Show Details

AMOREPACIFIC Corporation

Patent: US2009/176810 A1, 2009 ; Title/Abstract Full Text Show Details

% Inhibition

=

43.86

Hu, Oliver Yoa-Pu; Hsiong, Cheng-Huei; Kuo, Benjamin Pei-Chung; Pao, Li-Heng

Patent: US2003/166584 A1, 2003 ; Title/Abstract Full Text Show Details

% Inhibition

=

44.09

%

Inhibitor

Cytochrome P450 3A1 [Rattus norvegicus]:Wild

Hu, Oliver Yoa-Pu; Hsiong, Cheng-Huei; Kuo, Benjamin Pei-Chung; Pao, Li-Heng

Patent: US2003/166584 A1, 2003 ; Title/Abstract Full Text Show Details

% Inhibition

=

-2.47

%

Inhibitor

cytochrome p450 2c11 [rattus norvegicus]:Wild

Hu, Oliver Yoa-Pu; Wang, Hong-Jaan; Hsiong, Cheng-Huei; Pao, Li-Heng

Patent: US2006/69042 A1, 2006 ; Title/Abstract Full Text Show Details

%

=

63.1

%

Patent: EP2241573 A2, ...

Title/Abstract Full Text Show Details

%

Inhibitor

Cytochrome P450 3A1 [Rattus norvegicus]:Wild

Patent: US2003/166584 ...

Title/Abstract Full Text Show Details

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

BIO-FDandC Co., Ltd

Patent: EP2241573 A2, 2010 ; Title/Abstract Full Text Show Details

% Inhibition

=

43.86

Hu, Oliver Yoa-Pu; Hsiong, Cheng-Huei; Kuo, Benjamin Pei-Chung; Pao, Li-Heng

Patent: US2003/166584 A1, 2003 ; Title/Abstract Full Text Show Details

5.21

Ki

=

6.13

µM

Carbonic anhydrase 6 [human]:Wild

Oeztuerk Sarikaya, Sevim Beyza; Topal, Fevzi; Sentuerk, Murat; Guelin, Ihami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4259 - 4262 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

10

%

Tyrosinase [mushroom]:Wild

Patent: EP2241573 A2, ...

Title/Abstract Full Text Show Details

µM

Carbonic anhydrase [European sea bass]:Wild

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

BIO-FDandC Co., Ltd

Patent: EP2241573 A2, 2010 ; Title/Abstract Full Text Show Details

5.38

Ki

=

4.13

Oeztuerk Sarikaya, Sevim Beyza; Topal, Fevzi; Sentuerk, Murat; Guelin, Ihami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4259 - 4262 Title/Abstract Full Text View citing articles Show Details

5.65

Ki

=

2.25

µM

Carbonic anhydrase 2 [human]:Wild

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details


Oeztuerk Sarikaya, Sevim Beyza; Topal, Fevzi; Sentuerk, Murat; Guelin, Ihami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4259 - 4262 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

-3.05

%

Inhibitor

cytochrome p450 2c11 [rattus norvegicus]:Wild

Patent: US2006/69042 A...

Title/Abstract Full Text Show Details

Patent: US2006/69042 A...

Title/Abstract Full Text Show Details

Hu, Oliver Yoa-Pu; Wang, Hong-Jaan; Hsiong, Cheng-Huei; Pao, Li-Heng

Patent: US2006/69042 A1, 2006 ; Title/Abstract Full Text Show Details

% Inhibition

=

-0.97

%

Inhibitor

cytochrome p450 2c11 [rattus norvegicus]:Wild

Hu, Oliver Yoa-Pu; Wang, Hong-Jaan; Hsiong, Cheng-Huei; Pao, Li-Heng

Patent: US2006/69042 A1, 2006 ; Title/Abstract Full Text Show Details

%

=

75.1

%

Patent: EP2241573 A2, ...

Title/Abstract Full Text Show Details

µM

Carbonic anhydrase 1 [human]:Wild

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

BIO-FDandC Co., Ltd

Patent: EP2241573 A2, 2010 ; Title/Abstract Full Text Show Details

5.49

Ki

=

3.2

Oeztuerk Sarikaya, Sevim Beyza; Topal, Fevzi; Sentuerk, Murat; Guelin, Ihami; Supuran, Claudiu T.

Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4259 - 4262 Title/Abstract Full Text View citing articles Show Details

%

=

70.4

%

Patent: EP2241573 A2, ...

Title/Abstract Full Text Show Details

µM

HL-60 cell line

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

BIO-FDandC Co., Ltd

Patent: EP2241573 A2, 2010 ; Title/Abstract Full Text Show Details

4.67

IC50

=

21.2

Ahmed, Ejaz; Imran, Muhammad; Malik, Abdul; Ashraf, Muhammad

Archives of Pharmacal Research, 2006 , vol. 29, # 5 p. 343 - 347 Title/Abstract Full Text View citing articles Show Details

IC50

=

3.6

µg

HL-60 cell line

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Ahmed, Ejaz; Imran, Muhammad; Malik, Abdul; Ashraf, Muhammad

Archives of Pharmacal Research, 2006 , vol. 29, # 5 p. 343 - 347 Title/Abstract Full Text View citing articles Show Details

4.75

IC50

=

17.6

µM

Inhibitor

HL-60 cell line

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Ahmed, Ejaz; Imran, Muhammad; Malik, Abdul; Ashraf, Muhammad

Archives of Pharmacal Research, 2006 , vol. 29, # 5 p. 343 - 347 Title/Abstract Full Text View citing articles Show Details

4.75

IC50

=

3

µg/mL

Inhibitor

HL-60 cell line

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Ahmed, Ejaz; Imran, Muhammad; Malik, Abdul; Ashraf, Muhammad

Archives of Pharmacal Research, 2006 , vol. 29, # 5 p. 343 - 347 Title/Abstract Full Text View citing articles Show Details

5.14

IC50

=

7.3

µM

Inhibitor

SH-SY5Y

Bioorganic and Medicinal...


cell line

Title/Abstract Full Text View citing articles Show Details

Ji, Hong-Fang; Zhang, Hong-Yu; Shen, Liang

Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 15 p. 4095 - 4098 Title/Abstract Full Text View citing articles Show Details

4.23

IC50

=

10

µg/mL

Inhibitor

HepG2/2.2.15 cell line

3T3-L1 cell line

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Lee, Sung-Jin; Lee, Hak-Kyo; Jung, Min-Kyung; Mar, Woongchon

Biological and Pharmaceutical Bulletin, 2006 , vol. 29, # 10 p. 2131 - 2134 Title/Abstract Full Text View citing articles Show Details

Activity

31

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Ren, Yulin; Himmeldirk, Klaus; Chen, Xiaozhuo

Journal of Medicinal Chemistry, 2006 , vol. 49, # 9 p. 2829 - 2837 Title/Abstract Full Text View citing articles Show Details

6.24

Ki

=

580

nM

Inhibitor

RNA-directed DNA polymerase:Wild

Annual reports in medici...

Title/Abstract Full Text Show Details

DNA nucleotidylexotransferase:Wild

Annual reports in medici...

Title/Abstract Full Text Show Details

DNA polymerase gamma (Gamma):Wild

Annual reports in medici...

Title/Abstract Full Text Show Details

DNA polymerase (Epsilon) [Escherichia coli]:Wild

Annual reports in medici...

Title/Abstract Full Text Show Details

DNA polymerase alpha:Wild

Annual reports in medici...

Title/Abstract Full Text Show Details

Reverse transcriptase [Human immunodeficiency virus 1]:Wild

Annual reports in medici...

Title/Abstract Full Text Show Details

DNA polymerase beta (Beta):Wild

Annual reports in medici...

Title/Abstract Full Text Show Details

Pancreatic triacylglycerol lipase [pig]:Wild

Enzymology inhibition

Molecules, 2013 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Peter J. Hylands; Louis J. Nisbet

Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details

Activity

ND

Inhibitor

Peter J. Hylands; Louis J. Nisbet

Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details

Activity

ND

Inhibitor

Peter J. Hylands; Louis J. Nisbet

Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details

Activity

ND

Inhibitor

Peter J. Hylands; Louis J. Nisbet

Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details

Activity

ND

Inhibitor

Peter J. Hylands; Louis J. Nisbet

Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details

6.24

Ki

=

580

nM

Inhibitor

Peter J. Hylands; Louis J. Nisbet

Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details

Activity

ND

Inhibitor

Peter J. Hylands; Louis J. Nisbet

Annual reports in medicinal chemistry, 1991 , vol. 26, p. 259 - 269 Title/Abstract Full Text Show Details

1

IC50

>

300

µM


Kwon, O Jun; Bae, Jong-Sup; Lee, Ha Yeong; Hwang, Ju-Young; Lee, Eun-Woo; Ito, Hideyuki; Kim, Tae Hoon

Molecules, 2013 , vol. 18, # 9 p. 10629 - 10638 Title/Abstract Full Text View citing articles Show Details

3.53

IC50

294

µM

Hyaluronidase:Wild

Enzymology inhibition

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Enzymology inhibition

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Sgariglia, Melina A.; Soberon, Jose R.; Poveda Cabanes, Ana; Sampietro, Diego A.; Vattuone, Marta A.

Journal of Ethnopharmacology, 2013 , vol. 147, # 1 p. 63 - 73 Title/Abstract Full Text View citing articles Show Details

2.43

IC50

3.7

mM

Angiotensin-converting enzyme [rabbit]:Wild

lung

Al Shukor, Nadin; Van Camp, John; Gonzales, Gerard Bryan; Staljanssens, Dorien; Struijs, Karin; Zotti, Moises J.; Raes, Katleen; Smagghe, Guy

Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 48 p. 11832 - 11839 Title/Abstract Full Text View citing articles Show Details

2.72

% Inhibition

84

%

Angiotensin-converting enzyme [rabbit]:Wild

lung

Enzymology inhibition

10 mM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Al Shukor, Nadin; Van Camp, John; Gonzales, Gerard Bryan; Staljanssens, Dorien; Struijs, Karin; Zotti, Moises J.; Raes, Katleen; Smagghe, Guy

Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 48 p. 11832 - 11839 Title/Abstract Full Text View citing articles Show Details

2.64

% Inhibition

26

%

Angiotensin-converting enzyme [rabbit]:Wild

lung

Enzymology inhibition

0.800000 mM

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Al Shukor, Nadin; Van Camp, John; Gonzales, Gerard Bryan; Staljanssens, Dorien; Struijs, Karin; Zotti, Moises J.; Raes, Katleen; Smagghe, Guy

Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 48 p. 11832 - 11839 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

-12.2

%

aromatase [human]:Wild

cells

Enzymology inhibition

10 µM

Enzymology inhibition

0.312500 µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Park, Myeong Hyeon; Kim, In Sook; Kim, Sun-A; Na, Chun-Soo; Hong, Cheol Yi; Dong, Mi-Sook; Yoo, Hye Hyun

Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1730 - 1733 Title/Abstract Full Text View citing articles Show Details

IC50

ND

Neuraminidase N2 [Influenza A virus (A/R1/5+/1957(H2N2))]:Wild

Antiviral

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Abdel-Mageed, Wael M.; Bayoumi, Soad A.H.; Chen, Caixia; Vavricka, Christopher J.; Li, Li; Malik, Ajamaluddin; Dai, Huanqin; Song, Fuhang; Wang, Luoqiang; Zhang, Jingyu; Gao, George F.; Lv, Yali; Liu, Lihong; Liu, Xueting; Sayed, Hanaa M.; Zhang, Lixin

Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2236 - 2243 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

3

%

Neuraminidase N2 [Influenza A virus (A/R1/5+/1957(H2N2))]:Wild

Enzymology inhibition

100 µM

Antiviral

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Abdel-Mageed, Wael M.; Bayoumi, Soad A.H.; Chen, Caixia; Vavricka, Christopher J.; Li, Li; Malik, Ajamaluddin; Dai, Huanqin; Song, Fuhang; Wang, Luoqiang; Zhang, Jingyu; Gao, George F.; Lv, Yali; Liu, Lihong; Liu, Xueting; Sayed, Hanaa M.; Zhang, Lixin

Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2236 - 2243 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

NA

Protease 3C [Coxsackievirus B3]:Wild

Enzymology inhibition

100 µM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Abdel-Mageed, Wael M.; Bayoumi, Soad A.H.; Chen, Caixia; Vavricka, Christopher J.; Li, Li; Malik, Ajamaluddin; Dai, Huanqin; Song, Fuhang; Wang, Luoqiang; Zhang, Jingyu; Gao, George F.; Lv, Yali; Liu, Lihong; Liu, Xueting; Sayed, Hanaa M.; Zhang, Lixin

Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2236 - 2243 Title/Abstract Full Text View citing articles Show Details

5.25

% Inhibition

=

61.6

%

= 9 µM

scavenging

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details


Buemi, Maria Rosa; De Luca, Laura; Chimirri, Alba; Ferro, Stefania; Gitto, Rosaria; Alvarez-Builla, Julio; Alajarin, Ramon

Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 15 p. 4575 - 4580 Title/Abstract Full Text View citing articles Show Details

6.25

% Inhibition

>

94.1

%

= 9 µM

scavenging

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Buemi, Maria Rosa; De Luca, Laura; Chimirri, Alba; Ferro, Stefania; Gitto, Rosaria; Alvarez-Builla, Julio; Alajarin, Ramon

Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 15 p. 4575 - 4580 Title/Abstract Full Text View citing articles Show Details

Biodistribution

=

70.67

%

A7r5 cell line

= 30 µM

A7r5 cell line

= 30 µM

A7r5 cell line

= 30 µM

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Ou, Ting-Tsz; Lin, Ming-Cheng; Wu, Cheng-Hsun; Lin, Wea-Lung; Wang, Chau-Jong

Current Medicinal Chemistry, 2013 , vol. 20, # 31 p. 3944 - 3953 Title/Abstract Full Text View citing articles Show Details

5.8

% Inhibition

R

122.6

%

Antiproliferative

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Ou, Ting-Tsz; Lin, Ming-Cheng; Wu, Cheng-Hsun; Lin, Wea-Lung; Wang, Chau-Jong

Current Medicinal Chemistry, 2013 , vol. 20, # 31 p. 3944 - 3953 Title/Abstract Full Text View citing articles Show Details

Biodistribution

=

19.25

%

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Ou, Ting-Tsz; Lin, Ming-Cheng; Wu, Cheng-Hsun; Lin, Wea-Lung; Wang, Chau-Jong

Current Medicinal Chemistry, 2013 , vol. 20, # 31 p. 3944 - 3953 Title/Abstract Full Text View citing articles Show Details

5.11

IC50

=

7.7

µM

Inhibitor

PC12

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Liu, Yanqin; Pukala, Tara L.; Musgrave, Ian F.; Williams, Danielle M.; Dehle, Francis C.; Carver, John A.

Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6336 - 6340 Title/Abstract Full Text View citing articles Show Details

%

=

88

%

PC12

Cytotoxic

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Liu, Yanqin; Pukala, Tara L.; Musgrave, Ian F.; Williams, Danielle M.; Dehle, Francis C.; Carver, John A.

Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6336 - 6340 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

61.6

%

Gitto, Rosaria; De Luca, Laura; Ferro, Stefania; Russo, Emilio; De Sarro, Giovambattista; Chisari, Mariangela; Ciranna, Lucia; Alvarez-Builla, Julio; Alajarin, Ramon; Buemi, Maria Rosa; Chimirri, Alba

Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 1040 - 1048 Title/Abstract Full Text View citing articles Show Details

% Inhibition

>

94.1

%

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Gitto, Rosaria; De Luca, Laura; Ferro, Stefania; Russo, Emilio; De Sarro, Giovambattista; Chisari, Mariangela; Ciranna, Lucia; Alvarez-Builla, Julio; Alajarin, Ramon; Buemi, Maria Rosa; Chimirri, Alba

Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 1040 - 1048 Title/Abstract Full Text View citing articles Show Details

% Inhibition

>

93.9

%

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Gitto, Rosaria; De Luca, Laura; Ferro, Stefania; Russo, Emilio; De Sarro, Giovambattista; Chisari, Mariangela; Ciranna, Lucia; Alvarez-Builla, Julio; Alajarin, Ramon; Buemi, Maria Rosa; Chimirri, Alba

Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 3 p. 1040 - 1048 Title/Abstract Full Text View citing articles Show Details


5.27

EC50

=

5.34

µM

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Svinyarov, Ivan; Bogdanov, Milen G.

European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 198 - 206 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

10

%

Tyrosinase [mushroom]:Wild

Enzymology inhibition

100 µM

Patent: US8435548 B2, ...

Title/Abstract Full Text Show Details

10 µM

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Bio-FDandC Co., Ltd; Jung, Dai Hyun; Moh, Sang Hyun; Lee, Jung Hun; Kim, Su Jung; Kim, Hyung Sik; Seo, Hyo Hyun; Bae, Yeon Ja

Patent: US8435548 B2, 2013 ; Title/Abstract Full Text Show Details

1

% Inhibition

7.8

%

B16 melanoma 4A5 cell line

Flux release

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

14.5

%

B16 melanoma 4A5 cell line

Flux release

30 µM

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

4.13

% Inhibition

57.3

%

B16 melanoma 4A5 cell line

Flux release

100 µM

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

Activity

@

Antioxidant

Patent: WO2006/133523 ...

Title/Abstract Full Text Show Details

Antibiotic

Patent: WO2006/133523 ...

Title/Abstract Full Text Show Details

Antioxidant

Patent: WO2006/133523 ...

Title/Abstract Full Text Show Details

radical scavenging

Patent: WO2008/16593 A...

Title/Abstract Full Text Show Details

Antiaggregant

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

FLEN PHARMA N.V.; VAN DEN PLAS, Dave; DE SMET, Kris; SOLLIE, Philippe

Patent: WO2006/133523 A3, 2006 ; Title/Abstract Full Text Show Details

ENHANCED EFFECT

@

FLEN PHARMA N.V.; VAN DEN PLAS, Dave; DE SMET, Kris; SOLLIE, Philippe

Patent: WO2006/133523 A3, 2006 ; Title/Abstract Full Text Show Details

Activity

@

FLEN PHARMA N.V.; VAN DEN PLAS, Dave; DE SMET, Kris; SOLLIE, Philippe

Patent: WO2006/133523 A3, 2006 ; Title/Abstract Full Text Show Details

4.52

IC50

=

30

µM

TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

Patent: WO2008/16593 A2, 2008 ; Title/Abstract Full Text Show Details

DISAGGREGATION

=

30

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

Amyloid beta A4 protein:Wild


FLUORESCENCE INHIBITION

=

14

%

Inhibitor

Amyloid beta A4 protein:Wild

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Amyloid beta A4 protein:Wild

Antiaggregant

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Inhibitor

Amyloid beta A4 protein:Wild

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Inhibitor

Amyloid beta A4 protein:Wild

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Amyloid beta A4 protein:Wild

Antiaggregant

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Inhibitor

Amyloid beta A4 protein:Wild

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Inhibitor

Amyloid beta A4 protein:Wild

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Inhibitor

Amyloid beta A4 protein:Wild

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Amyloid beta A4 protein:Wild

Antiaggregant

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Amyloid beta A4 protein:Wild

Antiaggregant

Patent: US2001/47032 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

DISAGGREGATION

=

32

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

FLUORESCENCE INHIBITION

=

57

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

FLUORESCENCE INHIBITION

=

44

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

DISAGGREGATION

=

52

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

FLUORESCENCE INHIBITION

=

34

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

FLUORESCENCE INHIBITION

=

22

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

FLUORESCENCE INHIBITION

=

45

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

DISAGGREGATION

=

17

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

DISAGGREGATION

=

22

%

Castillo, Gerardo M.; Choi, Paula Y.; Snow, Alan D.

Patent: US2001/47032 A1, 2001 ; Title/Abstract Full Text Show Details

2.91

MIC

=

210

µg/mL


KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

0

mM

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: WO2012/119699 ...

Title/Abstract Full Text Show Details

Antioxidant

Patent: EP1893187 B1, ...

Title/Abstract Full Text Show Details

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

0

mM

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

0

mM

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

0

mM

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

0

mM

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

7

mM

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

0

mM

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

0

mM

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

ZI

=

0

mM

KING SAUD UNIVERSITY; TERRAMARK MARKENCREATION GMBH; AWAAD, Amani S.; SOLIMAN, Gamal A.; ALJABER, Nabila A.; AL-HAMAD, Tahani A.

Patent: WO2012/119699 A1, 2012 ; Title/Abstract Full Text Show Details

Activity

@

Flen Pharma N.V.

Patent: EP1893187 B1, 2008 ; Title/Abstract Full Text Show Details


Activity

@

Antioxidant

Patent: EP1893187 B1, ...

Title/Abstract Full Text Show Details

Antibiotic

Patent: EP1893187 B1, ...

Title/Abstract Full Text Show Details

%

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

Flen Pharma N.V.

Patent: EP1893187 B1, 2008 ; Title/Abstract Full Text Show Details

Activity

@

Flen Pharma N.V.

Patent: EP1893187 B1, 2008 ; Title/Abstract Full Text Show Details

%

=

8

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

11

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

99

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

82

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

3.58

IC50

=

45

µg/mL

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

3.82

IC50

=

26

µg/mL

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

96

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

91

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

17

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei


Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

90

%

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Antiinfective

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

HeLa cell line

Cytotoxic

Patent: US2009/137661 ...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

103

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

3.66

IC50

=

37

µg/mL

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

101

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

4.28

IC50

=

8.9

µg/mL

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

84

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

%

=

85

%

Shih, Ming-Kuang; Chao, Yu-Chou; Shih, Ying-Chu; Huang, Kuo-Kuei

Patent: US2009/137661 A1, 2009 ; Title/Abstract Full Text Show Details

2.93

MIC

=

200

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.63

MIC

=

400

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.63

MIC

=

400

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.63

MIC

=

400

µg/mL


Title/Abstract Full Text Show Details

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.63

MIC

=

400

µg/mL

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Antimicrobial

Patent: US2010/34757 A...

Title/Abstract Full Text Show Details

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.63

MIC

=

400

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.33

MIC

=

800

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.63

MIC

=

400

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.03

MIC

=

1600

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.33

MIC

=

800

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.93

MIC

=

200

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.63

MIC

=

400

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.03

MIC

=

1600

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ; Title/Abstract Full Text Show Details

2.33

MIC

=

800

µg/mL

Fujii, Mitsukiyo; Ushio, Shimpei; Iwaki, Kanso; Kyono, Fumiyo

Patent: US2010/34757 A1, 2010 ;


Title/Abstract Full Text Show Details

1

% Inhibition

1.4

%

peritoneal macrophage

Flux release

3 µM

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

17.1

%

peritoneal macrophage

Flux release

100 µM

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

4.2

%

peritoneal macrophage

Flux release

30 µM

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

8

%

peritoneal macrophage

Flux release

10 µM

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

4.52

IC50

0.03

mM

Tyrosinase [banana]:Wild

Enzymology inhibition

Russian Journal of Bioor...

Title/Abstract Full Text View citing articles Show Details

Karatas, Mert Olgun; Alici, Bulent; Cetinkaya, Engin; Bilen, Cigdem; Gencer, Nahit; Arslan, Oktay

Russian Journal of Bioorganic Chemistry, 2014 , vol. 40, # 4 p. 461 - 466Bioorg. Khim. Title/Abstract Full Text View citing articles Show Details

4.71

IC50

19.4

μM

Antioxidant

Chemistry of Natural Com...

Title/Abstract Full Text View citing articles Show Details

Ochir, Sarangowa; Yuki, Takehiro; Kanazawa, Tsutomu; Nishizawa, Makoto; Yamagishi, Takashi

Chemistry of Natural Compounds, 2013 , vol. 49, # 5 p. 940 - 942Khim. Prir. Soedin., 2013 , # 5 p. 806 - 807,2 Title/Abstract Full Text View citing articles Show Details

1.73

IC50

3.2

mg/ml

Antioxidant

Phytochemistry, 2013 , ...

Title/Abstract Full Text View citing articles Show Details

Tuominen, Anu

Phytochemistry, 2013 , vol. 95, p. 408 - 420 Title/Abstract Full Text View citing articles Show Details

5.54

EC50

2.9

μM

Antioxidant

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Kim, Jina; Hong, Victor Sukbong; Lee, Jinho

Archives of Pharmacal Research, 2014 , vol. 37, # 3 p. 324 - 331 Title/Abstract Full Text View citing articles Show Details

5.37

EC50

4.3

μM

Antioxidant

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Kim, Jina; Hong, Victor Sukbong; Lee, Jinho

Archives of Pharmacal Research, 2014 , vol. 37, # 3 p. 324 - 331 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not

50 μM

Antioxidant

Archives of Pharmacal Re...


active

Title/Abstract Full Text View citing articles Show Details

Kim, Jina; Hong, Victor Sukbong; Lee, Jinho

Archives of Pharmacal Research, 2014 , vol. 37, # 3 p. 324 - 331 Title/Abstract Full Text View citing articles Show Details

5.4

% Inhibition

88.3

%

erythrocyte

30 μM

Archives of Pharmacal Re...

Title/Abstract Full Text View citing articles Show Details

Kim, Jina; Hong, Victor Sukbong; Lee, Jinho

Archives of Pharmacal Research, 2014 , vol. 37, # 3 p. 324 - 331 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

16.47

%

Inhibitor

alpha-glucosidase:Wild

500 μM

Antidiabetic

Chemical Communications,...

Title/Abstract Full Text View citing articles Show Details

Deng, Shiren; Xia, Linbo; Xiao, Hongbin

Chemical Communications, 2014 , vol. 50, # 20 p. 2582 - 2584 Title/Abstract Full Text View citing articles Show Details

2.91

IC50

1235

μM

Inhibitor

alpha-glucosidase:Wild

Antidiabetic

Chemical Communications,...

Title/Abstract Full Text View citing articles Show Details

Deng, Shiren; Xia, Linbo; Xiao, Hongbin

Chemical Communications, 2014 , vol. 50, # 20 p. 2582 - 2584 Title/Abstract Full Text View citing articles Show Details

2.84

Ki

1430

μM

Inhibitor

alpha-glucosidase:Wild

Antidiabetic

Chemical Communications,...

Title/Abstract Full Text View citing articles Show Details

Deng, Shiren; Xia, Linbo; Xiao, Hongbin

Chemical Communications, 2014 , vol. 50, # 20 p. 2582 - 2584 Title/Abstract Full Text View citing articles Show Details

5.14

EC50

7.18

μM

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Ma, Fenghua; Onoda, Toshihisa; Li, Wei; Sasaki, Tatsunori; Ma, Ling; Zhang, Qingbo; Koike, Kazuo

Natural Product Research, 2013 , vol. 27, # 23 p. 2178 - 2182 Title/Abstract Full Text View citing articles Show Details

5.37

EC50

4.24

μM

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Ma, Fenghua; Onoda, Toshihisa; Li, Wei; Sasaki, Tatsunori; Ma, Ling; Zhang, Qingbo; Koike, Kazuo

Natural Product Research, 2013 , vol. 27, # 23 p. 2178 - 2182 Title/Abstract Full Text View citing articles Show Details

4.73

IC50

3.15

μg/ml

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Ambika; Singh, Pradeep Pratap; Chauhan

Natural Product Research, 2014 , vol. 28, # 10 p. 760 - 763 Title/Abstract Full Text View citing articles Show Details

% Inhibition

96.3

%

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Damascena; Souza; Almeida; Cunha; Curvello; Lima; Santos; Dias; Paixão; Quintans Júnior; Estevam; Araujo

Natural Product Research, 2014 , vol. 28, # 10 p. 753 - 756 Title/Abstract Full Text View citing articles Show Details

4.26

IC50

9.33

μg/ml

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details


Damascena; Souza; Almeida; Cunha; Curvello; Lima; Santos; Dias; Paixão; Quintans Júnior; Estevam; Araujo

Natural Product Research, 2014 , vol. 28, # 10 p. 753 - 756 Title/Abstract Full Text View citing articles Show Details

Antioxidant Activity Index

4.3

no unit

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Damascena; Souza; Almeida; Cunha; Curvello; Lima; Santos; Dias; Paixão; Quintans Júnior; Estevam; Araujo

Natural Product Research, 2014 , vol. 28, # 10 p. 753 - 756 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

19

%

Caco-2

50 μg/ml

Patent: US2014/128585 ...

Title/Abstract Full Text Show Details

20 μM

Patent: US2014/163045 ...

Title/Abstract Full Text Show Details

Patent: US2014/163045 ...

Title/Abstract Full Text Show Details

0 - 60 μM

Antioxidant

Patent: US2014/163045 ...

Title/Abstract Full Text Show Details

HEK293 cell line

100 nM 1 μM

Patent: US2014/249095 ...

Title/Abstract Full Text Show Details

0 - 10 μM

Food Chemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Nagaoka Perfumery Co., Ltd.; Sugimoto, Keiichiro; Nakayama, Hiroto; Nakagawa, Kazuya; Hayashi, Syuichi

Patent: US2014/128585 A1, 2014 ; Title/Abstract Full Text Show Details

1

% Inhibition

Not active

Inhibitor

xanthine oxidase [taurine cattle]:Wild

BAYLOR COLLEGE OF MEDICINE; Chen, Changyi; Lu, Jian-Ming; Yao, Qizhi

Patent: US2014/163045 A1, 2014 ; Title/Abstract Full Text Show Details

1

% Inhibition

Not active

Inhibitor

xanthine oxidase [taurine cattle]:Wild

BAYLOR COLLEGE OF MEDICINE; Chen, Changyi; Lu, Jian-Ming; Yao, Qizhi

Patent: US2014/163045 A1, 2014 ; Title/Abstract Full Text Show Details

Tested

Not published

BAYLOR COLLEGE OF MEDICINE; Chen, Changyi; Lu, Jian-Ming; Yao, Qizhi

Patent: US2014/163045 A1, 2014 ; Title/Abstract Full Text Show Details

%

90 - 95

%

Inhibitor

ATXN3/Q75:Wild

National Normal University; LEE-CHEN, Guey-Jen; CHEN, Chiung-Mei

Patent: US2014/249095 A1, 2014 ; Title/Abstract Full Text Show Details

4.95

IC50

11.3

μM

Salazar, Ricardo; Arambula-Villa, Geronimo; Hidalgo, Francisco J.; Zamora, Rosario

Food Chemistry, 2014 , vol. 151, p. 480 - 486 Title/Abstract Full Text View citing articles Show Details

5.09

IC50

8.18

μM

0 - 10 μM

Food Chemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Salazar, Ricardo; Arambula-Villa, Geronimo; Hidalgo, Francisco J.; Zamora, Rosario

Food Chemistry, 2014 , vol. 151, p. 480 - 486 Title/Abstract Full Text View citing articles Show Details

5.13

IC50

7.49

μM

0 - 10 μM

Food Chemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Salazar, Ricardo; Arambula-Villa, Geronimo; Hidalgo, Francisco J.; Zamora, Rosario

Food Chemistry, 2014 , vol. 151, p. 480 - 486 Title/Abstract Full Text View citing articles Show Details

4.52

% Inhibition

35.59

%

Inhibitor

Cytochrome P450 2E1:Wild

16.5 μM

Patent: US2014/38921 A...

Title/Abstract Full Text Show Details


NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien

Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details

4.15

% Inhibition

48.24

%

Inhibitor

Cytochrome P450 2E1:Wild

66 μM

Patent: US2014/38921 A...

Title/Abstract Full Text Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien

Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details

1

% Inhibition

-20.2

%

Inhibitor

Amidase [Mus musculus]:Wild

liver

100 μM

Patent: US2014/38921 A...

Title/Abstract Full Text Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien

Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details

1

% Inhibition

12

%

Inhibitor

Amidase [Mus musculus]:Wild

liver

1 μM

Patent: US2014/38921 A...

Title/Abstract Full Text Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien

Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details

1

% Inhibition

20

%

Inhibitor

Amidase [Mus musculus]:Wild

liver

10 μM

Patent: US2014/38921 A...

Title/Abstract Full Text Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien

Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details

1

% Inhibition

10.5

%

Inhibitor

Cytochrome P450 2E1 [human]:Wild

16.5 μM

Patent: US2014/38921 A...

Title/Abstract Full Text Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien

Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details

1

% Inhibition

18.79

%

Inhibitor

Cytochrome P450 2E1 [human]:Wild

33 μM

Patent: US2014/38921 A...

Title/Abstract Full Text Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien

Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details

3.77

% Inhibition

27.96

%

Inhibitor

Cytochrome P450 2E1 [human]:Wild

66 μM

Patent: US2014/38921 A...

Title/Abstract Full Text Show Details

NATIONAL DEFENSE EDUCATION AND RESEARCH FOUNDATION; Hu, Oliver Yaopu; Young, Tonho; Hsiong, Chenghuei; Chang, Wenliang; Shih, Tungyuan; Ho, Hsintien

Patent: US2014/38921 A1, 2014 ; Title/Abstract Full Text Show Details

pX

Parameter

Value (qual)

Value (quant)

Unit

%

=

4.3

%

Action on Target

Target

Tissue/Organ

Cell

Bioassay

HL-60 cell line

Dose

Effect

Reference (expand all/collapse all)

Cytotoxic

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Anti-RSV

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Kakumu, Akinori; Ninomiya, Masayuki; Efdi, Mai; Adfa, Morina; Hayashi, Masahiro; Tanaka, Kaori; Koketsu, Mamoru

Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 17 p. 4286 - 4290 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details


1

% Inhibition

Not active

Antiviral

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Antiviral

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Anti-Influenza

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Anti-Influenza

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Antiviral

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Anti-Herpes

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Anti-Influenza

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Antiviral

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Antiviral

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Antiviral

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details


Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Antiviral

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Antiviral

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

50

μM

CCRF-CEM cell line

Anti-HIV

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

50

μM

CCRF-CEM cell line

Anti-HIV

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

2.33

IC50

0.8

μg/μl

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Dah-Nouvlessounon, Durand; Adoukonou-Sagbadja, Hubert; Diarrassouba, Nafan; Sina, Haziz; Noumavo, Pacôme A.; Baba-Moussa, Farid; Adjanohoun, Adolphe; Gbenou, Joachim D.; Baba-Moussa, Lamine

International Journal of Pharmacy and Pharmaceutical Sciences, 2015 , vol. 7, # 6 p. 102 - 109 Title/Abstract Full Text View citing articles Show Details

3.89

% Inhibition

70

%

300 μM

Antioxidant

Food Chemistry, 2015 , ...

Title/Abstract Full Text Show Details

Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.

Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details

5.33

EC50

4.7

μM

Antioxidant

Food Chemistry, 2015 , ...

Title/Abstract Full Text Show Details

Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.

Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details

5.38

EC50

4.2

μM

Antioxidant

Food Chemistry, 2015 , ...

Title/Abstract Full Text Show Details

Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.

Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details

5.46

EC50

3.5

μM

Antioxidant

Food Chemistry, 2015 , ...

Title/Abstract Full Text Show Details

Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.

Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details

5.42

EC50

3.8

μM

Antioxidant

Food Chemistry, 2015 , ...

Title/Abstract Full Text Show Details


Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.

Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details

Time

60

min

Antioxidant

Food Chemistry, 2015 , ...

Title/Abstract Full Text Show Details

Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.

Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details

7.22

EC50

0.06

μM

Antioxidant

Food Chemistry, 2015 , ...

Title/Abstract Full Text Show Details

Aguilera, Yolanda; Herrera, Teresa; Bentez, Vanesa; Arribas, Silvia M.; Lpez De Pablo, Angel L.; Esteban, Rosa M.; Martn-Cabrejas, Mara A.

Food Chemistry, 2015 , vol. 170, p. 203 - 211 Title/Abstract Full Text Show Details

3.2

MIC

625

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

3.33

MIC

469

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

5000

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

5000

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

5000

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

5000

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

5000

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

5000

μM

Antibiotic :

ChemMedChem, 2015 , vol...


Enhancer

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

5000

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

5000

μM

Antibiotic : Enhancer

ChemMedChem, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Abouelhassan, Yasmeen; Garrison, Aaron T.; Bai, Fang; Norwood, Verrill M.; Nguyen, Minh Thu; Jin, Shouguang; Huigens, Robert W.

ChemMedChem, 2015 , vol. 10, # 7 p. 1157 - 1162 Title/Abstract Full Text View citing articles Show Details

IC50

Not Published

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Rakesh; Manukumar; Gowda, D. Channe

Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 5 p. 998 - 1003 Title/Abstract Full Text View citing articles Show Details

IC50

Not Published

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Rakesh; Manukumar; Gowda, D. Channe

Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 5 p. 998 - 1003 Title/Abstract Full Text View citing articles Show Details

4.42

IC50

6.5

μg/ml

Antioxidant

PLoS ONE, 2014 , vol. 9...

Title/Abstract Full Text View citing articles Show Details

Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan

PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details

2.77

IC50

0.29

mg/ml

Antioxidant

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Stankov-Jovanović; Ilić; Mitić; Mihajilov-Krstev; Simonović; Nikolić Mandić; Tabet; Cole

Journal of Pharmaceutical and Biomedical Analysis, 2015 , vol. 111, p. 78 - 90 Title/Abstract Full Text View citing articles Show Details

Trolox Equivalents

3.02

μg/ml

Antioxidant

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Stankov-Jovanović; Ilić; Mitić; Mihajilov-Krstev; Simonović; Nikolić Mandić; Tabet; Cole

Journal of Pharmaceutical and Biomedical Analysis, 2015 , vol. 111, p. 78 - 90 Title/Abstract Full Text View citing articles Show Details

Concentration

70.58

μg/mg

Antioxidant

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Stankov-Jovanović; Ilić; Mitić; Mihajilov-Krstev; Simonović; Nikolić Mandić; Tabet; Cole

Journal of Pharmaceutical and Biomedical Analysis, 2015 , vol. 111, p. 78 - 90 Title/Abstract Full Text View citing articles Show Details

% increase

Active

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details


Uy; Licuanan; Angeles; Bote; Macauyag; Hernandez; Jacinto; Guzman-Genuino

International Journal of Cancer Research, 2015 , vol. 11, # 2 p. 80 - 92 Title/Abstract Full Text View citing articles Show Details

4.79

IC50

=

2.79

µg/mL

scavenging

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Kim, Ki Hyun; Park, Yong Joo; Chung, Kyu Hyuck; Yip, M. L. Richard; Clardy, Jon; Senger, Donald; Cao, Shugeng

Journal of Natural Products, 2015 , vol. 78, # 2 p. 320 - 324 Title/Abstract Full Text View citing articles Show Details

Trolox Equivalents

18.6

no unit

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Prez-Areales, F. Javier; Di Pietro, Ornella; Espargar, Alba; Vallverd-Queralt, Anna; Galdeano, Carles; Ragusa, Ilaria M.; Viayna, Elisabet; Guillou, Catherine; Clos, M. Victria; Prez, Beln; Sabat, Raimon; LamuelaRavents, Rosa M.; Luque, F. Javier; Muoz-Torrero, Diego

Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 19 p. 5298 - 5307 Title/Abstract Full Text View citing articles Show Details

Trolox Equivalents

10.3

no unit

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Prez-Areales, F. Javier; Di Pietro, Ornella; Espargar, Alba; Vallverd-Queralt, Anna; Galdeano, Carles; Ragusa, Ilaria M.; Viayna, Elisabet; Guillou, Catherine; Clos, M. Victria; Prez, Beln; Sabat, Raimon; LamuelaRavents, Rosa M.; Luque, F. Javier; Muoz-Torrero, Diego

Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 19 p. 5298 - 5307 Title/Abstract Full Text View citing articles Show Details

3.42

IC50

382.4

μM

Inhibitor

Serine protease NS3 [Hepatitis C virus]:Wild

Fitoterapia, 2014 , vol...

Title/Abstract Full Text Show Details

20 μg/ml

Antioxidant

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Ajala, Olusegun S.; Jukov, Azzaya; Ma, Chao-Mei

Fitoterapia, 2014 , vol. 99, p. 117 - 123 Title/Abstract Full Text Show Details

5.21

% Inhibition

96.7

%

Sevindik, Handan G.; Güvenalp, Zühal; Yerdelen, Kadir Ö.; Yuca, Hafize; Demirezer, L. Ömür

Medicinal Chemistry Research, 2015 , vol. 24, # 11 p. 3794 - 3802 Title/Abstract Full Text View citing articles Show Details

5.15

IC50

0.007

mM

Antioxidant

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Sevindik, Handan G.; Güvenalp, Zühal; Yerdelen, Kadir Ö.; Yuca, Hafize; Demirezer, L. Ömür

Medicinal Chemistry Research, 2015 , vol. 24, # 11 p. 3794 - 3802 Title/Abstract Full Text View citing articles Show Details

5.29

IC50

0.876

μg/ml

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Ghate, Nikhil Baban; Chaudhuri, Dipankar; Das, Abhishek; Panja, Sourav; Mandal, Nripendranath

PLoS ONE, 2015 , vol. 10, # 5 art. no. E0128221 Title/Abstract Full Text View citing articles Show Details

1

IC50

100

μmol/ml

25 300 μmol/ml

Antioxidant

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Rakesh; Manukumar; Gowda, D. Channe

Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 5 p. 998 - 1003 Title/Abstract Full Text View citing articles Show Details

1.22

IC50

60

μmol/ml

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Rakesh; Manukumar; Gowda, D. Channe

Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 5 p. 998 - 1003 Title/Abstract Full Text View citing articles Show Details


3.83

% Increase

Active

HUVEC cell line

25 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

1

% Increase

Not active

HUVEC cell line

25 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

3.83

% Increase

Active

HUVEC cell line

25 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

4.13

% Increase

Active

HUVEC cell line

12.5 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

3.53

% Increase

Active

HUVEC cell line

50 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

3.23

% Increase

Active

HUVEC cell line

100 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

Fold-increase

1.4

no unit

HUVEC cell line

25 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

1

% Increase

Not active

HUVEC cell line

50 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

4.13

Amount increase

Active

HUVEC cell line

12.5 μg/ml 50 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

4.13

Amount increase

Active

HUVEC cell line

12.5 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details


Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

3.66

IC50

37.38

μg/ml

Inhibitor

Angiotensinconverting enzyme:Wild

16.5132 μg/ml

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

Amount

75.6 83.6

%

100 μM

Antioxidant

Journal of Inflammation ...

Title/Abstract Full Text View citing articles Show Details

Marimoutou, Méry; Le Sage, Fanny; Smadja, Jacqueline; D'Hellencourt, Christian Lefebvre; Gonthier, Marie-Paule; Da Silva, Christine Robert

Journal of Inflammation (United Kingdom), 2015 , vol. 12, # 1 art. no. 055 Title/Abstract Full Text View citing articles Show Details

4.14

IC50

12.2

μg/ml

Antioxidant

Bangladesh Journal of Ph...

Title/Abstract Full Text View citing articles Show Details

Mbhele, Nobuhle; Balogun, Fatai O.; Kazeem, Mutiu I.; Ashafa, Tom

Bangladesh Journal of Pharmacology, 2015 , vol. 10, # 1 p. 214 - 221 Title/Abstract Full Text View citing articles Show Details

4.08

IC50

14

μg/ml

Antioxidant

Bangladesh Journal of Ph...

Title/Abstract Full Text View citing articles Show Details

Mbhele, Nobuhle; Balogun, Fatai O.; Kazeem, Mutiu I.; Ashafa, Tom

Bangladesh Journal of Pharmacology, 2015 , vol. 10, # 1 p. 214 - 221 Title/Abstract Full Text View citing articles Show Details

5.05

IC50

1.5

μg/ml

Antioxidant

Bangladesh Journal of Ph...

Title/Abstract Full Text View citing articles Show Details

Mbhele, Nobuhle; Balogun, Fatai O.; Kazeem, Mutiu I.; Ashafa, Tom

Bangladesh Journal of Pharmacology, 2015 , vol. 10, # 1 p. 214 - 221 Title/Abstract Full Text View citing articles Show Details

% Inhibition

91.93

%

Antioxidant

Oriental Pharmacy and Ex...

Title/Abstract Full Text View citing articles Show Details

Boudaoud-Ouahmed, Hania; Tiab, Sid-Ali; Saidani, Nabil; Gherrou, Mehdi; Ziane, Keltoum; Atmani, Djebbar

Oriental Pharmacy and Experimental Medicine, 2015 , vol. 15, # 4 p. 353 - 363 Title/Abstract Full Text View citing articles Show Details

% Inhibition

63.86

%

Inhibitor

Lysine-specific demethylase 5B:Wild

Sf21 cell line

Patent: US2015/272939 ...

Title/Abstract Full Text Show Details

Inhibitor

xanthine oxidase:Wild

Antigout agent

Patent: WO2015/191034 ...

Title/Abstract Full Text Show Details

20 μM

Antigout agent

Patent: WO2015/191034 ...

Title/Abstract Full Text Show Details

Yale University; Yan, Qin; Sayegh, Joyce

Patent: US2015/272939 A1, 2015 ; Title/Abstract Full Text Show Details

1

% Inhibition50

Not active

BAYLOR COLLEGE OF MEDICINE; CHEN, Changyi; LU, Jian-Ming; YAO, Qizhi

Patent: WO2015/191034 A1, 2015 ; Title/Abstract Full Text Show Details

1

% Inhibition50

Not active

Inhibitor

xanthine oxidase:Wild

BAYLOR COLLEGE OF MEDICINE; CHEN, Changyi; LU, Jian-Ming; YAO, Qizhi

Patent: WO2015/191034 A1, 2015 ; Title/Abstract Full Text Show Details


3.53

IC50

0.05

mg/ml

Antioxidant

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2015 , vol. 72, # 6 p. 1201 - 1215 Title/Abstract Full Text View citing articles Show Details

2.93

IC50

0.2

mg/ml

Antiglycolytic

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2015 , vol. 72, # 6 p. 1201 - 1215 Title/Abstract Full Text View citing articles Show Details

4.8

IC50

=

15.66

µM

scavenging

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Liu, Jia-Bao; Ding, Ya-Si; Zhang, Ying; Chen, Jia-Bao; Cui, Bao-Song; Bai, Jin-Ye; Lin, Ming-Bao; Hou, Qi; Zhang, Pei-Cheng; Li, Shuai

Journal of Natural Products, 2015 , vol. 78, # 5 p. 1015 - 1025 Title/Abstract Full Text View citing articles Show Details

5.14

IC50

=

7.23

µM

scavenging

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Liu, Jia-Bao; Ding, Ya-Si; Zhang, Ying; Chen, Jia-Bao; Cui, Bao-Song; Bai, Jin-Ye; Lin, Ming-Bao; Hou, Qi; Zhang, Pei-Cheng; Li, Shuai

Journal of Natural Products, 2015 , vol. 78, # 5 p. 1015 - 1025 Title/Abstract Full Text View citing articles Show Details

5

EC50

10 - 12

µM

Antioxidant

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Jiang, Wen-Jun; Ishiuchi, Kan'Ichiro; Furukawa, Megumi; Takamiya, Tomoko; Kitanaka, Susumu; Iijima, Hiroshi

Bioorganic and Medicinal Chemistry, 2015 , vol. 23, # 21 p. 6922 - 6929 Title/Abstract Full Text View citing articles Show Details

% reduction

-59.3

%

THP-1 cell line

0.3 μg/ml

European Journal of Nutr...

Title/Abstract Full Text View citing articles Show Details

Del Bo, Cristian; Cao, Yi; Roursgaard, Martin; Riso, Patrizia; Porrini, Marisa; Loft, Steffen; Moller, Peter

European Journal of Nutrition, 2016 , vol. 55, # 1 p. 171 - 182 Title/Abstract Full Text View citing articles Show Details

6.54

% reduction

Active

THP-1 cell line

0.29 58.8 μM

European Journal of Nutr...

Title/Abstract Full Text View citing articles Show Details

Del Bo, Cristian; Cao, Yi; Roursgaard, Martin; Riso, Patrizia; Porrini, Marisa; Loft, Steffen; Moller, Peter

European Journal of Nutrition, 2016 , vol. 55, # 1 p. 171 - 182 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

103.1

%

Inhibitor

Isocitrate dehydrogenase [NADP] [human]:Mutated

inhibitory activity

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kim, Hyo-Joon; Fei, Xiang; Cho, Seok-Cheol; Choi, Bu Young; Ahn, Hee-Chul; Lee, Kyeong; Seo, Seung-Yong; Keum, Young-Sam

Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 23 p. 5625 - 5631 Title/Abstract Full Text View citing articles Show Details

% Inhibition

=

97.4

%

Inhibitor

Isocitrate dehydrogenase [NADP] [human]:Wild

inhibitory activity

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kim, Hyo-Joon; Fei, Xiang; Cho, Seok-Cheol; Choi, Bu Young; Ahn, Hee-Chul; Lee, Kyeong; Seo, Seung-Yong; Keum, Young-Sam

Bioorganic and Medicinal Chemistry Letters, 2015 , vol. 25, # 23 p. 5625 - 5631 Title/Abstract Full Text View citing articles Show Details

3.48

IC50

332.6

μM

Inhibitor

Pyruvate kinase PKM [human]:Wild

Journal of Enzyme Inhibi...

Title/Abstract Full Text View citing articles Show Details


Aslan, Erdem; Guler, Caglar; Adem, Sevki

Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 , vol. 31, # 2 p. 314 - 317 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Active

Inhibitor

Tyrosinase [mushroom]:Wild

Patent: WO2016/14529 A...

Title/Abstract Full Text Show Details

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

WISYS TECHNOLOGY FOUNDATION, INC.; HUANG, Cheng-Chen; MONTE, Aaron P.

Patent: WO2016/14529 A1, 2016 ; Title/Abstract Full Text Show Details

3.04

IC50

156.29

μg/ml

Prakasia, Pressy P.; Nair, Ashalatha S.

International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details

2.95

% Inhibition

56.53

%

250 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Prakasia, Pressy P.; Nair, Ashalatha S.

International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details

3.1

% Inhibition

47.82

%

125 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Prakasia, Pressy P.; Nair, Ashalatha S.

International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details

2.48

% Inhibition

78.26

%

2000 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Prakasia, Pressy P.; Nair, Ashalatha S.

International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details

2.72

% Inhibition

60.86

%

500 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Prakasia, Pressy P.; Nair, Ashalatha S.

International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details

2.5

% Inhibition

65.22

%

1000 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Prakasia, Pressy P.; Nair, Ashalatha S.

International Journal of Pharmacy and Pharmaceutical Sciences, 2016 , vol. 8, # 3 p. 85 - 91 Title/Abstract Full Text View citing articles Show Details

4

% Inhibition

Active

Inhibitor

2-oxoglutarate and iron-dependent oxygenase domaincontaining protein 1 (OGFOD1) [human]:Wild

100 μM

Patent: US9228224 B2, ...

Title/Abstract Full Text Show Details

ISIS INNOVATION LIMITED; Schofield, Christopher Joseph; Wolf, Alexander; Ge, Wei; Thalhammer, Armin; Loenarz, Christoph; Ratcliffe, Peter John; Cockman, Matthew Edward

Patent: US9228224 B2, 2016 ; Title/Abstract Full Text Show Details

% Inhibition

77.2

%

1 - 20 μM

Atherosclerosis, 2016 , ...

Title/Abstract Full Text View citing articles Show Details

Jun, Moon Young; Karki, Rajendra; Paudel, Keshav Raj; Sharma, Bhesh Raj; Adhikari, Deepak; Kim, Dong-Wook

Atherosclerosis, 2016 , vol. 248, p. 179 - 189


Title/Abstract Full Text View citing articles Show Details

2.36

IC50

734.81

μg/ml

PLoS ONE, 2016 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Saha, Manas Ranjan; Dey, Priyankar; Begum, Sainiara; De, Bratati; Chaudhuri, Tapas Kr.; De Sarker, Dilip; Das, Abhaya Prasad; Sen, Arnab

PLoS ONE, 2016 , vol. 11, # 3 art. no. E0150574 Title/Abstract Full Text View citing articles Show Details

Amount

95.2

%

2 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

52.2

%

14 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

81.9

%

6 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

61.9

%

10 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

3.6

%

2 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

12.2

%

6 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

28.6

%

14 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

23.4

%

10 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

1

%

2 μM

Dislipidemia

Phytotherapy Research, 2...


Title/Abstract Full Text View citing articles Show Details Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

14.6

%

10 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

6.1

%

6 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

18.8

%

14 μM

Dislipidemia

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% Increase

Not active

blood

erythrocyte

290 μM

Free Radical Research, 2...

Title/Abstract Full Text View citing articles Show Details

Tedesco, Idolo; Moccia, Stefania; Volpe, Silvestro; Alfieri, Giovanna; Strollo, Daniela; Bilotto, Stefania; Spagnuolo, Carmela; Di Renzo, Massimo; Aquino, Rita P.; Russo, Gian Luigi

Free Radical Research, 2016 , vol. 50, # 5 p. 557 - 569 Title/Abstract Full Text View citing articles Show Details

4.53

% Inhibition

Active

5 - 200 μg/ml

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Chaudhuri, Dipankar; Ghate, Nikhil Baban; Panja, Sourav; Das, Abhishek; Mandal, Nripendranath

PLoS ONE, 2015 , vol. 10, # 12 art. no. E0144280 Title/Abstract Full Text View citing articles Show Details

4.53

% Inhibition

Active

5 - 120 μg/ml

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Chaudhuri, Dipankar; Ghate, Nikhil Baban; Panja, Sourav; Das, Abhishek; Mandal, Nripendranath

PLoS ONE, 2015 , vol. 10, # 12 art. no. E0144280 Title/Abstract Full Text View citing articles Show Details

2.29

IC50

0.876

mg/ml

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Chaudhuri, Dipankar; Ghate, Nikhil Baban; Panja, Sourav; Das, Abhishek; Mandal, Nripendranath

PLoS ONE, 2015 , vol. 10, # 12 art. no. E0144280 Title/Abstract Full Text View citing articles Show Details

Amount

93.154

%

Antiradical

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Politi, Flávio A.S.; Queiroz-Fernandes, Geisiany M.; Rodrigues, Edvânio R.; Freitas, Jolindo A.; Pietro, Rosemeire C.L.R.

Microbial Pathogenesis, 2016 , vol. 95, p. 15 - 20 Title/Abstract Full Text View citing articles Show Details

3.81

IC50

155.21

μM

10 1000 μM

Antioxidant

Toxicology in Vitro, 201...

Title/Abstract Full Text View citing articles Show Details


Paudel, Keshav Raj; Karki, Rajendra; Kim, Dong-Wook

Toxicology in Vitro, 2016 , vol. 34, p. 16 - 25 Title/Abstract Full Text View citing articles Show Details

% decrease50

High

10 100 μM

Antioxidant

Toxicology in Vitro, 201...

Title/Abstract Full Text View citing articles Show Details

Paudel, Keshav Raj; Karki, Rajendra; Kim, Dong-Wook

Toxicology in Vitro, 2016 , vol. 34, p. 16 - 25 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Inhibitor

xanthine oxidase [taurine cattle]:Wild

Patent: US2015/353471 ...

Title/Abstract Full Text Show Details

Patent: US2015/353471 ...

Title/Abstract Full Text Show Details

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Baylor College of Medicine; Chen, Changyi; YAO, Qizhi; LU, Jian-Ming

Patent: US2015/353471 A1, 2015 ; Title/Abstract Full Text Show Details

% scavenging

High

Baylor College of Medicine; Chen, Changyi; YAO, Qizhi; LU, Jian-Ming

Patent: US2015/353471 A1, 2015 ; Title/Abstract Full Text Show Details

5.34

IC50

0.77

μg/ml

Fakhrudin; Khairunnisa; Azzahra; Ajiningtyas

International Journal of Pharmaceutical and Clinical Research, 2016 , vol. 8, # 5 p. 352 - 356 Title/Abstract Full Text View citing articles Show Details

4.11

IC50

78.11

μM

rbl-2h3

Antiallergic

Journal of Natural Medic...

Title/Abstract Full Text View citing articles Show Details

Shi, Yan-Hong; Zhu, Shu; Tamura, Takayuki; Kadowaki, Makoto; Wang, Zhengtao; Yoshimatsu, Kayo; Komatsu, Katsuko

Journal of Natural Medicines, 2016 , vol. 70, # 2 p. 234 - 240 Title/Abstract Full Text View citing articles Show Details

4.52

IC50

30.4

μM

10 1000 μM

Antioxidant

Carbohydrate Research, 2...

Title/Abstract Full Text View citing articles Show Details

Shaikh, Qurat-Ul-Ain; Yang, Meiting; Memon, Khadim Hussain; Lateef, Mehreen; Na, Du; Wan, Shengbiao; Eric, Deslandes; Zhang, Lijuan; Jiang, Tao

Carbohydrate Research, 2016 , vol. 430, p. 72 - 81 Title/Abstract Full Text View citing articles Show Details

5.15

EC50

7

μM

51000 μM

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia

European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details

Trolox equivalent

1.18

no unit

1 - 30 μM

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia

European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details

6.15

IC50

0.7

μM

0.1 μM - 40 mM

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia

European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details

4.62

IC50

4.12

μg/ml

RAW 264.7

3.125 -

Drug Design, Development...


cell line

100 μg/ml

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng

Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details

4.09

IC50

13.92

μg/ml

peripheral blood mononuclear cell

peripheral blood mononuclear cell

3.125 100 μg/ml

3.125 100 μg/ml

2 mg/ml

Antioxidant

Drug Design, Development...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng

Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details

3.68

IC50

35.28

μg/ml

Drug Design, Development...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng

Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details

% Scavenging

93.13

%

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Siddiqui, Maqsood A.; Rasheed, Saima; Saquib, Quaiser; Al-Khedhairy, Abdulaziz A.; Al-Said, Mansour S.; Musarrat, Javed; Choudhary, Muhammad Iqbal

BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 276 Title/Abstract Full Text View citing articles Show Details

4.63

IC50

0.004

mg/ml

Antioxidant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Siddiqui, Maqsood A.; Rasheed, Saima; Saquib, Quaiser; Al-Khedhairy, Abdulaziz A.; Al-Said, Mansour S.; Musarrat, Javed; Choudhary, Muhammad Iqbal

BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 276 Title/Abstract Full Text View citing articles Show Details

% reduction

High

<= 250 μg/ml

Antioxidant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Afsar, Tayyaba; Razak, Suhail; Khan, Muhammad Rashid; Mawash, Saadia; Almajwal, Ali; Shabir, Maria; Haq, Ihsan Ul

BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 258 Title/Abstract Full Text View citing articles Show Details

3.73

EC50

32

μg/ml

25-250 μg/ml

Antioxidant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Afsar, Tayyaba; Razak, Suhail; Khan, Muhammad Rashid; Mawash, Saadia; Almajwal, Ali; Shabir, Maria; Haq, Ihsan Ul

BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 258 Title/Abstract Full Text View citing articles Show Details

3.77

EC50

29

μg/ml

<= 100 μM

Antioxidant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Afsar, Tayyaba; Razak, Suhail; Khan, Muhammad Rashid; Mawash, Saadia; Almajwal, Ali; Shabir, Maria; Haq, Ihsan Ul

BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 258 Title/Abstract Full Text View citing articles Show Details

5.3

EC50

5-6

μM

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana

PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details

Second-order rate constant (k2)

8.3

μM-1*s1

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details


Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana

PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details

3.68

IC50

210 340

μM

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana

PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details

Number

85.1

no unit

peripheral blood mononuclear cell

peripheral blood mononuclear cell

31.25 μM

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana

PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details

Number

76.9

no unit

62.5 μM

Antioxidant

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Martinčič, Rok; Mravljak, Janez; Švajger, Urban; Perdih, Andrej; Anderluh, Marko; Novič, Marjana

PLoS ONE, 2015 , vol. 10, # 10 art. no. E0140602 Title/Abstract Full Text View citing articles Show Details

4.6

IC50

4.3

μg/ml

Antioxidant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Padumadasa, Chayanika; Dharmadana, Durga; Abeysekera, Ajit; Thammitiyagodage, Mayuri

BMC Complementary and Alternative Medicine, 2016 , vol. 16, # 1 art. no. 345 Title/Abstract Full Text View citing articles Show Details

2.93

IC50

0.2

mg/ml

Inhibitor

Hemoglobin:Wild

30 240 μg/ml

Antidiabetic

30 μg/ml

Antidiabetic

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

% Inhibition50

High

Inhibitor

Hemoglobin:Wild

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

3.45

% Inhibition

Active

Inhibitor

alpha-glucosidase [Saccharomyces cerevisiae]:Wild

60 μg/ml

Antidiabetic

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

3.53

IC50

0.05

mg/ml

30 240 μg/ml

Antioxidant

30 μg/ml

Antioxidant

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

% scavenging

High

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details


% scavenging

High

60 μg/ml

Antioxidant

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

% scavenging

High

120 μg/ml

Antioxidant

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

% scavenging

High

240 μg/ml

Antioxidant

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

% Inhibition50

High

Inhibitor

Hemoglobin:Wild

60 μg/ml

Antidiabetic

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

% Inhibition50

High

Inhibitor

Hemoglobin:Wild

120 μg/ml

Antidiabetic

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

% Inhibition50

High

Inhibitor

Hemoglobin:Wild

240 μg/ml

Antidiabetic

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

3.15

% Inhibition

Active

Inhibitor

alpha-glucosidase [Saccharomyces cerevisiae]:Wild

120 μg/ml

Antidiabetic

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

2.85

% Inhibition

Active

Inhibitor

alpha-glucosidase [Saccharomyces cerevisiae]:Wild

240 μg/ml

Antidiabetic

Acta Poloniae Pharmaceut...

Title/Abstract Full Text View citing articles Show Details

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2016 , vol. 73, # 2 p. 403 - 417 Title/Abstract Full Text View citing articles Show Details

4

% Inhibition

Active

100 200 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details

Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

% Inhibition

High

MDCK cell line

1 - 100 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details


Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

% Inhibition

High

MDCK cell line

1 - 100 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details

Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

% Reduction

59 - 93

%

MDCK cell line

1 - 400 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details

Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

% Reduction

59 - 93

%

MDCK cell line

1 - 400 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details

Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

% Reduction

59 - 93

%

MDCK cell line

1-400 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details

Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

% Reduction

59 - 93

%

MDCK cell line

1- 400 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details

Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

5.41

% Inhibition

Active

3.9 1000 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details

Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

5.41

% Inhibition

Active

3.9 1000 μM

Anti-Influenza

Viruses, 2016 , vol. 8,...

Title/Abstract Full Text View citing articles Show Details

Lee, Ji-Hye; Oh, Mi; Seok, Jong Hyeon; Kim, Sella; Lee, Dan Bi; Bae, Garam; Bae, Hae-In; Bae, Seon Young; Hong, Young-Min; Kwon, Sang-Oh; Lee, Dong-Hun; Song, Chang-Seon; Mun, Ji Young; Chung, Mi Sook; Kim, Kyung Hyun

Viruses, 2016 , vol. 8, # 6 art. no. 157 Title/Abstract Full Text View citing articles Show Details

3.2

MIC

625

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

Antistaphylococcal

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details


1

MIC

>

5000

μM

Antibiotic

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Antibiotic

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Antibiotic

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Antibiotic

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Antibiotic

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Antistaphylococcal

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Antibiotic

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Anti-MRSA

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Anti-MRSA

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Anti-MRSA

Patent: WO2016/154051 ...

Title/Abstract Full Text Show Details

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

1

MIC

>

5000

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

1

MIC

>

5000

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

3.33

MIC

469

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

1

MIC

>

5000

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

1

MIC

>

5000

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

3.2

MIC

625

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

1

MIC

>

5000

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

1

MIC

>

5000

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

1

MIC

>

5000

μM

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.; HUIGENS, Robert, William, III; ABOUELHASSAN, Yasmeen; GARRISON, Aaron

Patent: WO2016/154051 A1, 2016 ; Title/Abstract Full Text Show Details

6

% Decrease

Active

Caco-2 cell line

1 μM


Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

5

% Decrease

Active

Caco-2 cell line

10 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

6

% Decrease

Active

Caco-2 cell line

1 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

5

% Decrease

Active

Caco-2 cell line

10 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

7

% Decrease

Active

Caco-2 cell line

0.1 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

2

nmol/mg protein

Caco-2 cell line

10 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

1.8

nmol/mg protein

Caco-2 cell line

0.1 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

2

nmol/mg protein

Caco-2 cell line

1 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

241

ng/mg protein

Caco-2 cell line

0.1 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

236.9

ng/mg protein

Caco-2 cell line

10 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details


Amount

248.7

ng/mg protein

Caco-2 cell line

1 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

108.6

mU/mg protein

Caco-2 cell line

1 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

102.6

mU/mg protein

Caco-2 cell line

10 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

101.8

mU/mg protein

Caco-2 cell line

0.1 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

2.9

mU/mg protein

Caco-2 cell line

0.1 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

2.5

mU/mg protein

Caco-2 cell line

10 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

Amount

2.6

mU/mg protein

Caco-2 cell line

1 μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

4900

μM

Inhibitor

Thymidylate synthase ThyX [human]:Wild

10 100 μM

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Borsari, Chiara; Lucian, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-Da-silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Iacono, Lucia Dello; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jiménez-Antón, María D.; Corral, María J.; Alunda, José Ma; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola

Journal of Medicinal Chemistry, 2016 , vol. 59, # 16 p. 7598 - 7616 Title/Abstract Full Text View citing articles Show Details

4.03

IC50

94.3

μM

Inhibitor

dihydrofolate reductase [human]:Wild

10 100 μM

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Borsari, Chiara; Lucian, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-Da-silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Iacono, Lucia Dello; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jiménez-Antón, María D.; Corral, María J.; Alunda, José Ma; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola

Journal of Medicinal Chemistry, 2016 , vol. 59, # 16 p. 7598 - 7616


Title/Abstract Full Text View citing articles Show Details

4.15

IC50

70.6

μM

Inhibitor

Pteridine reductase 1 [Trypanosoma brucei]:Wild

10 100 μM

Antitrypanosomal

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Borsari, Chiara; Lucian, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-Da-silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Iacono, Lucia Dello; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jiménez-Antón, María D.; Corral, María J.; Alunda, José Ma; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola

Journal of Medicinal Chemistry, 2016 , vol. 59, # 16 p. 7598 - 7616 Title/Abstract Full Text View citing articles Show Details

5.4

IC50

4

μM

10 100 μM

Antitrypanosomal

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Borsari, Chiara; Lucian, Rosaria; Pozzi, Cecilia; Poehner, Ina; Henrich, Stefan; Trande, Matteo; Cordeiro-Da-silva, Anabela; Santarem, Nuno; Baptista, Catarina; Tait, Annalisa; Di Pisa, Flavio; Iacono, Lucia Dello; Landi, Giacomo; Gul, Sheraz; Wolf, Markus; Kuzikov, Maria; Ellinger, Bernhard; Reinshagen, Jeanette; Witt, Gesa; Gribbon, Philip; Kohler, Manfred; Keminer, Oliver; Behrens, Birte; Costantino, Luca; Nevado, Paloma Tejera; Bifeld, Eugenia; Eick, Julia; Clos, Joachim; Torrado, Juan; Jiménez-Antón, María D.; Corral, María J.; Alunda, José Ma; Pellati, Federica; Wade, Rebecca C.; Ferrari, Stefania; Mangani, Stefano; Costi, Maria Paola

Journal of Medicinal Chemistry, 2016 , vol. 59, # 16 p. 7598 - 7616 Title/Abstract Full Text View citing articles Show Details

4.22

% Inhibition

71

%

Inhibitor

UDP-glucose 6dehydrogenase:Wild

25 μg/ml

Patent: US2016/310528 ...

Title/Abstract Full Text Show Details

Tyrosinase:Wild

B16

Patent: EP2467134 B1, ...

Title/Abstract Full Text Show Details

NUtech Ventures; Simpson, Melanie A.; Barycki, Joseph

Patent: US2016/310528 A1, 2016 ; Title/Abstract Full Text Show Details

% Inhibition

Active

Inhibitor

Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola

Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details

%

89.2

%

Inhibitor

Tyrosinase:Wild

B16

0.05 mg/ml

Patent: EP2467134 B1, ...

Title/Abstract Full Text Show Details

Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola

Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details

%

83.4

%

Inhibitor

Tyrosinase:Wild

B16

0.075 mg/ml

Patent: EP2467134 B1, ...

Title/Abstract Full Text Show Details

Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola

Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details

%

92.5

%

Inhibitor

Tyrosinase:Wild

B16

0.025 mg/ml

Patent: EP2467134 B1, ...

Title/Abstract Full Text Show Details

Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola

Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details

Concentration

22.2949

μg/ml

Inhibitor

Tyrosinase:Wild

epidermis cell

25 μg/ml

Patent: EP2467134 B1, ...

Title/Abstract Full Text Show Details

Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola

Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details

%

84.0503

%

Inhibitor

Tyrosinase:Wild

epidermis cell

25 μg/ml

Patent: EP2467134 B1, ...

Title/Abstract Full Text Show Details

Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola

Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details

5.59

IC50

0.44

μg/ml

1-10 μg/ml

Antioxidant

Journal of Photochemistr...

Title/Abstract Full Text View citing articles Show Details


García-Bores; Espinosa-González; Reyna-Campos; Cruz-Toscano; Benítez-Flores; Hernández-Delgado; Flores-Maya; Urzúa-Meza; Peñalosa-Castro; Céspedes-Acuña; Avila-Acevedo

Journal of Photochemistry and Photobiology B: Biology, 2017 , vol. 167, p. 72 - 81 Title/Abstract Full Text View citing articles Show Details

4.57

IC50

26.8

μM

Antiplasmodic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Aldulaimi, Omar; Uche, Fidelia I.; Hameed, Hamza; Mbye, Haddijatou; Ullah, Imran; Drijfhout, Falko; Claridge, Timothy D.W.; Horrocks, Paul; Li, Wen-Wu

Journal of Ethnopharmacology, 2017 , vol. 198, p. 221 - 225 Title/Abstract Full Text View citing articles Show Details

5.51

% Inhibition

95.3

%

10 μg/ml

Antioxidant

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

25 μg/ml

Antioxidant

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

50 μg/ml

Antioxidant

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

250 μg/ml

Antioxidant

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

500 μg/ml

Antioxidant

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

125 μg/ml

Antioxidant

Archiv der Pharmazie, 20...

Title/Abstract Full Text View citing articles Show Details

12.5 25 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin

Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details

5.11

% Inhibition

95.4

%

Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin

Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details

4.81

% Inhibition

95.46

%

Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin

Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

18.96

%

Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin

Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

24.35

%

Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin

Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

15.51

%

Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin

Archiv der Pharmazie, 2017 , vol. 350, # 2 art. no. 1600285 Title/Abstract Full Text View citing articles Show Details

4.13

% Inhibition

Active

RAW 264.7 cell line

Alam, Md Badrul; Kwon, Kyoo-Ri; Lee, Seok-Hyun; Lee, Sang-Han

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 266 Title/Abstract Full Text View citing articles Show Details

pX

Parameter

Value (qual)

Value (quant)

Unit

Action on Target

Target

Tissue/Organ

Cell

Bioassay

Dose

Effect

Reference (expand all/collapse all)


1

% Inhibition

18.56

%

RAW 264.7 cell line

50 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

BJ

12.5 50 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

3 -30 μg/ml

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Apoptotic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Apoptotic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Apoptotic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

Drug Research, 2017 , v...

Title/Abstract Full Text View citing articles Show Details

Alam, Md Badrul; Kwon, Kyoo-Ri; Lee, Seok-Hyun; Lee, Sang-Han

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 266 Title/Abstract Full Text View citing articles Show Details

4.13

% Inhibition

Active

Alam, Md Badrul; Kwon, Kyoo-Ri; Lee, Seok-Hyun; Lee, Sang-Han

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 266 Title/Abstract Full Text View citing articles Show Details

4.75

% Inhibition

Active

Alam, Md Badrul; Kwon, Kyoo-Ri; Lee, Seok-Hyun; Lee, Sang-Han

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 266 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

SK-MEL-28 cell line

Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

HeLa cell line

Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

A-375 cell line

Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details

5.15

EC50

1.2

μg/ml

Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details

5.08

IC50

1.4

μg/ml

Golakoti, Trimurtulu; Kancharla, Hari Krishna; Meka, Bharani; Murthy

Medicinal Chemistry Research, 2016 , vol. 25, # 12 p. 2906 - 2915 Title/Abstract Full Text View citing articles Show Details

5.05

IC50

9.01

μM

5 - 50 μM

Lone, Shabir H.; Rehman, Shakeel U; Bhat, Khursheed A.

Drug Research, 2017 , vol. 67, # 2 art. no. DRUGRES2016-06-1205, p. 111 - 118 Title/Abstract Full Text View citing articles Show Details

7.28

IC50

0.009

μg/ml

Inhibitor

Carbonic anhydrase 1 [human]:Wild

Journal of Enzyme Inhibi...

Title/Abstract Full Text View citing articles Show Details


Aygul, Imdat; Yaylaci Karahalil, Fatma; Supuran, Claudiu T.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 , vol. 31, p. 119 - 124 Title/Abstract Full Text View citing articles Show Details

6.69

IC50

0.035

μg/ml

Inhibitor

Carbonic anhydrase 2 [human]:Wild

Journal of Enzyme Inhibi...

Title/Abstract Full Text View citing articles Show Details

Aygul, Imdat; Yaylaci Karahalil, Fatma; Supuran, Claudiu T.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 , vol. 31, p. 119 - 124 Title/Abstract Full Text View citing articles Show Details

6.39

% Inhibition

~

90

%

0.625 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Mohan, Shikha; Gupta, Damodar

Biomedicine and Pharmacotherapy, 2017 , vol. 89, p. 781 - 795 Title/Abstract Full Text View citing articles Show Details

3.91

IC50

20.8

μg/ml

MDCK cell line

Anticytopathic

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Tran, Thu Thi; Kim, Meehyein; Jang, Yejin; Lee, Hye Won; Nguyen, Hoa Thi; Nguyen, Thanh Ngoc; Park, Hae Woong; Le Dang, Quang; Kim, Jin-Cheol

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 162 Title/Abstract Full Text View citing articles Show Details

3.99

IC50

17.5

μg/ml

MDCK cell line

Anticytopathic

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Tran, Thu Thi; Kim, Meehyein; Jang, Yejin; Lee, Hye Won; Nguyen, Hoa Thi; Nguyen, Thanh Ngoc; Park, Hae Woong; Le Dang, Quang; Kim, Jin-Cheol

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 162 Title/Abstract Full Text View citing articles Show Details

3.84

IC50

24.5

μg/ml

MDCK cell line

Anticytopathic

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Tran, Thu Thi; Kim, Meehyein; Jang, Yejin; Lee, Hye Won; Nguyen, Hoa Thi; Nguyen, Thanh Ngoc; Park, Hae Woong; Le Dang, Quang; Kim, Jin-Cheol

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 162 Title/Abstract Full Text View citing articles Show Details

4.43

IC50

37

μM

Antioxidant

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Kumboonma, Pakit; Senawong, Thanaset; Saenglee, Somprasong; Yenjai, Chavi; Phaosiri, Chanokbhorn

Medicinal Chemistry Research, 2017 , vol. 26, # 3 p. 650 - 661 Title/Abstract Full Text View citing articles Show Details

3.67

IC50

214.38

μM

Inhibitor

glycogen phosphorylasealpha:Wild

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Ablat, Abdulwali; Halabi, Mohammed Farouq; Mohamad, Jamaludin; Hasnan, Muhammad Hafiz Husna; Hazni, Hazrina; Teh, Ser-huy; Shilpi, Jamil A.; Mohamed, Zulqarnain; Awang, Khalijah

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 94 Title/Abstract Full Text View citing articles Show Details

3.56

IC50

277.04

μM

Inhibitor

alpha-glucosidase:Wild

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Ablat, Abdulwali; Halabi, Mohammed Farouq; Mohamad, Jamaludin; Hasnan, Muhammad Hafiz Husna; Hazni, Hazrina; Teh, Ser-huy; Shilpi, Jamil A.; Mohamed, Zulqarnain; Awang, Khalijah

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 94 Title/Abstract Full Text View citing articles Show Details

2.75

IC50

0.3

mg/ml

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Talla, Emmanuel; Tamfu, Alfred Ngenge; Gade, Isaac Sylvère; Yanda, Lambert; Mbafor, Joseph Tanyi; Laurent, Sophie; Elst, Luce Vander; Popova, Milena; Bankova, Vassya

Natural Product Research, 2017 , vol. 31, # 12 p. 1379 - 1389 Title/Abstract Full Text View citing articles Show Details


5.36

IC50

4.35

μM

Antioxidant

International Journal of...

Title/Abstract Full Text Show Details

Antioxidant

Cytotechnology, 2017 , ...

Title/Abstract Full Text View citing articles Show Details

Hamed, Manal Mortady; Abdalla, Aboelfetoh Mohamed; Ghareeb, Mosad Ahmed; Saleh, Said Abdelhalim

International Journal of Pharmacy and Pharmaceutical Sciences, 2017 , vol. 9, # 5 p. 240 - 247 Title/Abstract Full Text Show Details

2.29

IC50

876.24

μg/ml

Basu, Tapasree; Panja, Sourav; Ghate, Nikhil Baban; Chaudhuri, Dipankar; Mandal, Nripendranath

Cytotechnology, 2017 , vol. 69, # 2 p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

3.62

EC50

240

μmol/l

Antioxidant

Journal of Chromatograph...

Title/Abstract Full Text View citing articles Show Details

Li, Yuanyuan; Li, Lingxi; Cui, Yan; Zhang, Shuting; Sun, Baoshan

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017 , vol. 1054, p. 105 - 113 Title/Abstract Full Text View citing articles Show Details

Ferric reducing antioxidant power (FRAP)

7.5

μmol/l

Antioxidant

Journal of Chromatograph...

Title/Abstract Full Text View citing articles Show Details

Li, Yuanyuan; Li, Lingxi; Cui, Yan; Zhang, Shuting; Sun, Baoshan

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017 , vol. 1054, p. 105 - 113 Title/Abstract Full Text View citing articles Show Details

4.41

EC50

39

μmol/l

Antioxidant

Journal of Chromatograph...

Title/Abstract Full Text View citing articles Show Details

Li, Yuanyuan; Li, Lingxi; Cui, Yan; Zhang, Shuting; Sun, Baoshan

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017 , vol. 1054, p. 105 - 113 Title/Abstract Full Text View citing articles Show Details

% Inhibition

73.86 81.57

%

RAW 264.7 cell line

Antiinflammatory

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Low

blood

3.125 - 50 μg/ml

Immunosuppressant

3.125 - 50 μg/ml

Antiinflammatory

3.125 - 50 μg/ml

Antiinflammatory

3.125 - 50 μg/ml

Immunosuppressant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

2.91

IC50

207.38

μg/ml

peripheral blood mononuclear cell

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

3.32

IC50

81.82

μg/ml

peripheral blood mononuclear cell

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

4.83

IC50

2.53

μg/ml

blood

polymorphonuclear cell

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details


Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

4.52

IC50

5.11

μg/ml

blood

3.125 - 50 μg/ml

Immunosuppressant

3.125 - 50 μg/ml

Immunosuppressant

Antichemotactic

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

4.78

IC50

2.82

μg/ml

blood

polymorphonuclear cell

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

4.32

IC50

8.22

μg/ml

blood

polymorphonuclear cell

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

4.23

IC50

9.99

μg/ml

blood

3.125 - 50 μg/ml

Immunosuppressant

3.125 - 50 μg/ml

Antiinflammatory

6.25 μg/ml

Immunosuppressant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

3.85

IC50

24.17

μg/ml

RAW 264.7 cell line

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

% Activity

88.77

μg/ml

blood

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

3.87

% Activity

81.33

%

blood

100 μg/ml

Immunosuppressant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

3.57

% Activity

68.6

%

blood

100 μg/ml

Immunosuppressant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

4.95

% Activity

76.5

%

blood

6.25 μg/ml

Immunosuppressant

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211


Title/Abstract Full Text View citing articles Show Details

3.53

% decrease

Active

50 400 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

3.53

% Inhibition

Active

50 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

% Inhibition

High

40 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

Fold-decrease

1.98

no unit

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

Fold-decrease

1.38

no unit

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

Fold-decrease

1.07

no unit

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

Fold-decrease

1.06

no unit

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

Fold-decrease

1.04

no unit

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

% decrease

45.9

%

80 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

Fold-decrease

1.1

no unit

80

Phagocytic

Microbial Pathogenesis, ...


μg/ml

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

stoichiometric factor (n)

2.03

no unit

<= 400 μM

Antioxidant

10 μM

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Zhao, Peng-Fei; Liu, Zai-Qun

European Journal of Medicinal Chemistry, 2017 , vol. 135, p. 458 - 466 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Inhibitor

Solute carrier organic anion transporter family member 2B1:Wild

HEK293 cell line

Drug Metabolism and Phar...

Title/Abstract Full Text View citing articles Show Details

Kondo, Ayuko; Narumi, Katsuya; Ogura, Jiro; Sasaki, Ai; Yabe, Keisuke; Kobayashi, Taku; Furugen, Ayako; Kobayashi, Masaki; Iseki, Ken

Drug Metabolism and Pharmacokinetics, 2017 , vol. 32, # 2 p. 145 - 150 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Low

peritoneum macrophage

2 μM

Antiinflammatory

Patent: EP2381935 B1, ...

Title/Abstract Full Text Show Details

Antioxidant

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Lycored Ltd.; ZELKHA, Morris; LEVY, Rachel; PARAN, Esther; SHARONI, Yoav; LEVY, Joseph

Patent: EP2381935 B1, 2016 ; Title/Abstract Full Text Show Details

Equivalent amount of vitamin C

332.52

mg

Pan, Guojun; Li, Xuehui; Zhao, Long; Wu, Meng; Su, Chao; Li, Xuzhe; Zhang, Yongmin; Yu, Peng; Teng, Yuou; Lu, Kui

European Journal of Medicinal Chemistry, 2017 , vol. 138, p. 577 - 589 Title/Abstract Full Text View citing articles Show Details

% apoptosis

12.5

%

PC12

10 μM

Cytoprotective

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Pan, Guojun; Li, Xuehui; Zhao, Long; Wu, Meng; Su, Chao; Li, Xuzhe; Zhang, Yongmin; Yu, Peng; Teng, Yuou; Lu, Kui

European Journal of Medicinal Chemistry, 2017 , vol. 138, p. 577 - 589 Title/Abstract Full Text View citing articles Show Details

% apoptosis

2.8

%

PC12

100 μM

Cytoprotective

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Pan, Guojun; Li, Xuehui; Zhao, Long; Wu, Meng; Su, Chao; Li, Xuzhe; Zhang, Yongmin; Yu, Peng; Teng, Yuou; Lu, Kui

European Journal of Medicinal Chemistry, 2017 , vol. 138, p. 577 - 589 Title/Abstract Full Text View citing articles Show Details

% increase

1019

%

NHEK cell line

0.03 mg/ml

Skinprotective

Patent: US2017/112737 ...

Title/Abstract Full Text Show Details

0.0003 mg/ml

Skinprotective

Patent: US2017/112737 ...

Title/Abstract Full Text Show Details

0.01 mg/ml

Skinprotective

Patent: US2017/112737 ...

Title/Abstract Full Text Show Details

GREENPHARMA; BIOALTERNATIVES; BERNARD, Philippe; BERNARD, François-Xavier; HIMBERT, Franck

Patent: US2017/112737 A1, 2017 ; Title/Abstract Full Text Show Details

% increase

165

%

NHEK cell line

GREENPHARMA; BIOALTERNATIVES; BERNARD, Philippe; BERNARD, François-Xavier; HIMBERT, Franck

Patent: US2017/112737 A1, 2017 ; Title/Abstract Full Text Show Details

% increase

588

%

NHEK cell line

GREENPHARMA; BIOALTERNATIVES; BERNARD, Philippe; BERNARD, François-Xavier; HIMBERT, Franck

Patent: US2017/112737 A1, 2017 ; Title/Abstract Full Text Show Details


4.73

IC50

3.185

mg/l

1100 mg/l

Antioxidant

1100 mg/l

Antioxidant

1100 mg/l

Antioxidant

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Chen, Hongxia; Wang, Chengzhang; Zhou, Hao; Tao, Ran; Ye, Jianzhong; Li, Wenjun

Natural Product Research, 2017 , vol. 31, # 13 p. 1573 - 1577 Title/Abstract Full Text View citing articles Show Details

4.49

IC50

5.55

mg/l

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Chen, Hongxia; Wang, Chengzhang; Zhou, Hao; Tao, Ran; Ye, Jianzhong; Li, Wenjun

Natural Product Research, 2017 , vol. 31, # 13 p. 1573 - 1577 Title/Abstract Full Text View citing articles Show Details

4.16

IC50

11.64

mg/l

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Chen, Hongxia; Wang, Chengzhang; Zhou, Hao; Tao, Ran; Ye, Jianzhong; Li, Wenjun

Natural Product Research, 2017 , vol. 31, # 13 p. 1573 - 1577 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Active

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Active

Antioxidant

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1.83

MIC

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1.83

MIC

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details


Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

2500 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

1250 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

625 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

312.5 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

2500 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

1250 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

625 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details


1

ZI

Not active

312.5 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

2500 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

1250 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

625 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

312.5 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

ZI

13

mm

1250 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

ZI

17

mm

2500 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

625 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

312.5 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

ZI

12

mm

1250 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details


Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

ZI

17

mm

2500 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

625 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

312.5 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

2500 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

1250 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

625 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

312.5 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

2500 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

1250 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052


Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

625 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

312.5 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

ZI

10

mm

2500 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

1250 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

625 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

ZI

Not active

312.5 μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

2500

μg/ml

Antibiotic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Baldemir, Ayşe; Gökşen, Neslihan; Ildız, Nilay; Karatoprak, Gökçe Şeker; Koşar, Müberra

Chemistry and Biodiversity, 2017 , vol. 14, # 7 art. no. E1700052 Title/Abstract Full Text View citing articles Show Details

4.52

IC50

30

μM

SW1353 cell line

Antiinflammatory

Natural Product Research...


Title/Abstract Full Text View citing articles Show Details Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Inhibitor

nitric-oxide synthase [Mus musculus]:Wild

RAW 264.7 cell line

<= 50 μg/ml

Antiinflammatory

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

SW1353 cell line

<= 50 μg/ml

Antiinflammatory

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details

4.68

IC50

3.53

μg/ml

Antioxidant

3 Biotech, 2017 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Singh, Dhananjaya P.; Prabha, Ratna; Verma, Shaloo; Meena, Kamlesh K.; Yandigeri, Mahesh

3 Biotech, 2017 , vol. 7, # 2 art. no. 134 Title/Abstract Full Text View citing articles Show Details

4.28

IC50

8.85

μg/ml

Antioxidant

3 Biotech, 2017 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Singh, Dhananjaya P.; Prabha, Ratna; Verma, Shaloo; Meena, Kamlesh K.; Yandigeri, Mahesh

3 Biotech, 2017 , vol. 7, # 2 art. no. 134 Title/Abstract Full Text View citing articles Show Details

4.34

IC50

7.84

μg/ml

Antioxidant

3 Biotech, 2017 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Singh, Dhananjaya P.; Prabha, Ratna; Verma, Shaloo; Meena, Kamlesh K.; Yandigeri, Mahesh

3 Biotech, 2017 , vol. 7, # 2 art. no. 134 Title/Abstract Full Text View citing articles Show Details

5.38

IC50

0.71

μg/ml

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Kapepula, Paulin Mutwale; Mbombo Mungitshi, Patricia; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba Ngoyi, Dieudonné; Kalenda, Pascal Dibungi T.; Kabamba Ngombe, Nadege; Serteyn, Didier; Tits, Monique; Frédérich, Michel; Tamfum Muyembe, Jean-Jacques

Natural Product Research, 2017 , vol. 31, # 16 p. 1940 - 1943 Title/Abstract Full Text View citing articles Show Details

5.2

IC50

1.07

μg/ml

20 μl

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Kapepula, Paulin Mutwale; Mbombo Mungitshi, Patricia; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba Ngoyi, Dieudonné; Kalenda, Pascal Dibungi T.; Kabamba Ngombe, Nadege; Serteyn, Didier; Tits, Monique; Frédérich, Michel; Tamfum Muyembe, Jean-Jacques

Natural Product Research, 2017 , vol. 31, # 16 p. 1940 - 1943 Title/Abstract Full Text View citing articles Show Details

4.93

% Decrease

Active

HL-60 cell line

2-40 μg/ml

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Kapepula, Paulin Mutwale; Mbombo Mungitshi, Patricia; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba Ngoyi, Dieudonné; Kalenda, Pascal Dibungi T.; Kabamba Ngombe, Nadege; Serteyn, Didier; Tits, Monique; Frédérich, Michel; Tamfum Muyembe, Jean-Jacques

Natural Product Research, 2017 , vol. 31, # 16 p. 1940 - 1943 Title/Abstract Full Text View citing articles Show Details

Tested

Not published

RAW 264.7 cell line

Antiinflammatory

Patent: WO2017/66965 A...

Title/Abstract Full Text Show Details


THE UNIVERSITY OF HONG KONG; RONG, Jianhui

Patent: WO2017/66965 A1, 2017 ; Title/Abstract Full Text Show Details

4.05

Amount increase

Active

peritoneum macrophage

15 60 μg/ml

Phagocytic

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

peritoneum macrophage

15 μg/ml

Phagocytic

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

4.05

Amount increase

Active

peritoneum macrophage

15 μg/ml

Phagocytic

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

4.02

IC50

16.408

μg/ml

6.25 100 μg/ml

Anti-Leishmaniasis

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

3.83

% Inhibition

80

%

100 μg/ml

Anti-Leishmaniasis

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

2.98

% Inhibition

25

%

peritoneum macrophage

60 μg/ml

Anti-Leishmaniasis

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

3.52

% Inhibition

37

%

peritoneum macrophage

30 μg/ml

Anti-Leishmaniasis

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

3.95

% Inhibition

~

44

%

peritoneum macrophage

15 μg/ml

Anti-Leishmaniasis

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details


4.53

IC50

5.042

μg/ml

peritoneum macrophage

15 30 μg/ml

Anti-Leishmaniasis

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

<

20

%

Inhibitor

Carboxypeptidase G2:Chimera + Guanine nucleotide exchange factor sopE2 [Sainionella typhimuriurn]:Chimera

25 μM

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Tsou, Lun K.; Yount, Jacob S.; Hang, Howard C.

Bioorganic and Medicinal Chemistry, 2017 , vol. 25, # 11 p. 2883 - 2887 Title/Abstract Full Text View citing articles Show Details

3.93

% Inhibition

Active

MCF-7 cell line

20 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

de Almeida, Thiago Silva; Neto, José Joaquim Lopes; de Sousa, Nathanna Mateus; Pessoa, Igor Parra; Vieira, Leonardo Rogério; de Medeiros, Jackeline Lima; Boligon, Aline Augusti; Hamers, Astrid R.M.; Farias, Davi Felipe; Peijnenburg, Ad; Carvalho, Ana Fontenele Urano

Biomedicine and Pharmacotherapy, 2017 , vol. 93, p. 1261 - 1268 Title/Abstract Full Text View citing articles Show Details

3.93

% Inhibition

Active

MCF-7 cell line

20 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

de Almeida, Thiago Silva; Neto, José Joaquim Lopes; de Sousa, Nathanna Mateus; Pessoa, Igor Parra; Vieira, Leonardo Rogério; de Medeiros, Jackeline Lima; Boligon, Aline Augusti; Hamers, Astrid R.M.; Farias, Davi Felipe; Peijnenburg, Ad; Carvalho, Ana Fontenele Urano

Biomedicine and Pharmacotherapy, 2017 , vol. 93, p. 1261 - 1268 Title/Abstract Full Text View citing articles Show Details

3.93

% decrease

Active

MCF-7 cell line

20 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

de Almeida, Thiago Silva; Neto, José Joaquim Lopes; de Sousa, Nathanna Mateus; Pessoa, Igor Parra; Vieira, Leonardo Rogério; de Medeiros, Jackeline Lima; Boligon, Aline Augusti; Hamers, Astrid R.M.; Farias, Davi Felipe; Peijnenburg, Ad; Carvalho, Ana Fontenele Urano

Biomedicine and Pharmacotherapy, 2017 , vol. 93, p. 1261 - 1268 Title/Abstract Full Text View citing articles Show Details

3.93

% decrease

Active

MCF-7 cell line

20 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

de Almeida, Thiago Silva; Neto, José Joaquim Lopes; de Sousa, Nathanna Mateus; Pessoa, Igor Parra; Vieira, Leonardo Rogério; de Medeiros, Jackeline Lima; Boligon, Aline Augusti; Hamers, Astrid R.M.; Farias, Davi Felipe; Peijnenburg, Ad; Carvalho, Ana Fontenele Urano

Biomedicine and Pharmacotherapy, 2017 , vol. 93, p. 1261 - 1268 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Active

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Kandikattu, Hemanth Kumar; Rachitha; Jayashree; Krupashree; Sukhith; Majid, Abdul; Amruta, Narayanappa; Khanum, Farhath

Biomedicine and Pharmacotherapy, 2017 , vol. 91, p. 191 - 201 Title/Abstract Full Text View citing articles Show Details

4.53

% Inhibition

Active

5 μg/ml

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Kandikattu, Hemanth Kumar; Rachitha; Jayashree; Krupashree; Sukhith; Majid, Abdul; Amruta, Narayanappa; Khanum, Farhath

Biomedicine and Pharmacotherapy, 2017 , vol. 91, p. 191 - 201 Title/Abstract Full Text View citing articles Show Details

4.6

% Inhibition

50

%

NPC-BM1

25 μM

Antiinvasive

International Journal of...

Title/Abstract Full Text View citing articles Show Details


Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

5

% Inhibition

Active

NPC-BM1

10 50 μM

Antiinvasive

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

5

% increase

Active

NPC-BM1

10 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

5

% decrease

Active

NPC-BM1

10 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

5

% decrease

Active

NPC-BM1

10- 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

5

% decrease

Active

NPC-BM1

10- 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

5

% decrease

Active

NPC-BM1

10- 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

4.3

% decrease

Active

NPC-BM1

50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

5

% decrease

Active

NPC-BM1

10- 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

4.6

% decrease

Active

NPC-BM1

25 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details


4.6

% decrease

Active

NPC-BM1

25 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

4.3

% decrease

Active

NPC-BM1

50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

4.3

% decrease

Active

NPC-BM1

50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

% decrease

20

%

NPC-BM1

10 μM

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

% decrease

40

%

NPC-BM1

25 μM

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

% decrease

70

%

NPC-BM1

50 μM

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

5

% decrease

Active

NPC-BM1

10-50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

4.3

% decrease

Active

NPC-BM1

50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

200

μM

Inhibitor

Angiotensinconverting enzyme [Leporidae]:Wild

lung

Journal of Natural Medic...

Title/Abstract Full Text View citing articles Show Details

Jenis, Janar; Kim, Jeong Yoon; Uddin, Zia; Song, Yeong Hun; Lee, Hyeong-Hwan; Park, Ki Hun

Journal of Natural Medicines, 2017 , vol. 71, # 4 p. 650 - 658 Title/Abstract Full Text View citing articles Show Details

Trolox equivalent antioxidant

1606.3

no unit

plasma

0.05 0.5 mg/ml

Antioxidant

Nutrients, 2017 , vol. ...

Title/Abstract Full Text View citing articles Show Details


capacity

Selby-Pham, Sophie N. B.; Cottrell, Jeremy J.; Dunshea, Frank R.; Ng, Ken; Bennett, Louise E.; Howell, Kate S.

Nutrients, 2017 , vol. 9, # 7 art. no. 758 Title/Abstract Full Text View citing articles Show Details

Concentration

68.7

nmol

plasma

0.05 0.5 mg/ml

Antioxidant

0.1 200 μg/ml

Antioxidant

Nutrients, 2017 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Selby-Pham, Sophie N. B.; Cottrell, Jeremy J.; Dunshea, Frank R.; Ng, Ken; Bennett, Louise E.; Howell, Kate S.

Nutrients, 2017 , vol. 9, # 7 art. no. 758 Title/Abstract Full Text View citing articles Show Details

5.14

IC50

7.2

μM

Journal of Natural Produ...

Title/Abstract Full Text View citing articles Show Details

Badral, Duger; Odonbayar, Batsukh; Murata, Toshihiro; Munkhjargal, Tserendorj; Tuvshintulga, Bumduuren; Igarashi, Ikuo; Suganuma, Keisuke; Inoue, Noboru; Brantner, Adelheid H.; Odontuya, Gendaram; Sasaki, Kenroh; Batkhuu, Javzan

Journal of Natural Products, 2017 , vol. 80, # 9 p. 2416 - 2423 Title/Abstract Full Text View citing articles Show Details

3.83

% decrease

Active

25.0 μg/ml

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

3.53

% decrease

Active

50.0 μg/ml

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

Concentration

4.03

μg/ml

25.0 μg/ml

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

Concentration

1.79

μg/ml

50.0 μg/ml

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

4.13

MIC

12.5 100

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

50 - 100

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

50 - 100

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu


Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

4.13

MIC

12.5

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

50

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

4.13

MIC

12.5 100

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

4.13

MIC

12.5 100

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

50 - 100

μg/ml

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

3.88

IC50

22.35

μg/ml

Antioxidant

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details

4.76

IC50

2.95

μg/ml

Antioxidant

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details

5.18

IC50

1.13

μg/ml

Antioxidant

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details


5.08

IC50

1.43

μg/ml

Antioxidant

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details

4.14

IC50

12.37

μg/ml

Antioxidant

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details

3.78

IC50

28.21

μg/ml

Antioxidant

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Gul, Hina; Ahmad, Mushtaq; Zafar, Muhammad; Sheeraz Ahmad, Muhammad; Abid, Ambreen; Hira, Syeda; Shah, Imam; Gulfraz, Muhammad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1305 - 1309 Title/Abstract Full Text View citing articles Show Details

Catechin equivalent

6498.5

μmol/g

2.5 μg/ml

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.

Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details

5.77

IC50

1.7

μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.

Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details

6.27

IC50

0.54

μM

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.

Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details

5.72

IC50

1.9

μM

brain

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.

Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details

Trolox equivalent

8992.2

μmol/g

1 μg/ml

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.

Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details

% Inhibition

80.4

%

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.

Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details

% Inhibition

77.5

%

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details


Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.

Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details

3.75

IC50

30.31

μg/ml

Inhibitor

ATPase [Rattus norvegicus]:Wild

pancreas

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

5.06

IC50

1.48

μg/ml

Inhibitor

glucose-6phosphatase [Rattus norvegicus]:Wild

liver

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

4.59

IC50

4.4

μg/ml

pancreas

15 240 μg/ml

15 240 μg/ml

15 240 μg/ml

15 240 μg/ml

15 240 μg/ml

15 240 μg/ml

15 240 μg/ml

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

7.28

IC50

0.009

μg/ml

liver

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

3.3

IC50

85.11

μg/ml

liver

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

2.5

IC50

537.03

μg/ml

liver

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1000

μg/ml

pancreas

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

2.47

IC50

575.43

μg/ml

pancreas

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1000

μg/ml

pancreas

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details


4.85

IC50

2.38

μg/ml

pancreas

15 240 μg/ml

15 240 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

1000

μg/ml

liver

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Mopuri, Ramgopal; Oyebode, Olajumoke A.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 37 - 47 Title/Abstract Full Text View citing articles Show Details

%

80

%

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Elansary, Hosam O.; Salem, Mohamed Z.M.; Ashmawy, Nader A.; Yessoufou, Kowiyou; El-Settawy, Ahmed A.A.

Natural Product Research, 2017 , vol. 31, # 24 p. 2927 - 2930 Title/Abstract Full Text View citing articles Show Details

4.58

IC50

4.5

μg/ml

Inhibitor

Tyrosinase [mushroom]:Wild

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Balbontin, Cristian; Avila, Jose G.; Dominguez, Mariana; Alarcon, Julio; Paz, Cristian; Burgos, Viviana; Ortiz, Leandro; Peñaloza-Castro, Ignacio; Seigler, David S.; Kubo, Isao

Food and Chemical Toxicology, 2017 , vol. 109, p. 984 - 995 Title/Abstract Full Text View citing articles Show Details

4.14

IC50

12.2

μg/ml

Antioxidant

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Balbontin, Cristian; Avila, Jose G.; Dominguez, Mariana; Alarcon, Julio; Paz, Cristian; Burgos, Viviana; Ortiz, Leandro; Peñaloza-Castro, Ignacio; Seigler, David S.; Kubo, Isao

Food and Chemical Toxicology, 2017 , vol. 109, p. 984 - 995 Title/Abstract Full Text View citing articles Show Details

5.38

IC50

0.71

μg/ml

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel

Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details

4.41

IC50

6.6

μg/ml

neutrophil

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel

Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details

5.2

IC50

1.07

μg/ml

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel

Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details

5

% Inhibition

Active

HL-60 cell line

10 500 μM

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel

Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details


6

% Inhibition

Active

Inhibitor

Myeloperoxidase:Wild

1 - 10 μM

Antiinflammatory

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Kapepula, Paulin Mutwale; Kabamba Ngombe, Nadege; Tshisekedi Tshibangu, Pascal; Tsumbu, César; Franck, Thierry; Mouithys-Mickalad, Ange; Mumba, Dieudonné; Tshala-Katumbay, Désiré; Serteyn, Didier; Tits, Monique; Angenot, Luc; Kalenda, Pascal Dibungi T.; Frédérich, Michel

Natural Product Research, 2017 , vol. 31, # 24 p. 2885 - 2892 Title/Abstract Full Text View citing articles Show Details

3.91

IC50

0.021

mg/ml

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Antioxidant

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

M’sou, Soufiane; Alifriqui, Mohamed; Romane, Abderrahmane

Natural Product Research, 2017 , vol. 31, # 23 p. 2797 - 2800 Title/Abstract Full Text View citing articles Show Details

2.74

EC50

0.31

mg/ml

M’sou, Soufiane; Alifriqui, Mohamed; Romane, Abderrahmane

Natural Product Research, 2017 , vol. 31, # 23 p. 2797 - 2800 Title/Abstract Full Text View citing articles Show Details

% of cells in SUBG1 phase

<=

8.9

MDA-MB-231 cell line

%

25-50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

pX

Parameter

Value (qual)

5.3

% Increase

Active

Value (quant)

Unit

Action on Target

Target

Tissue/Organ

Cell

Bioassay

Dose

Effect

Reference (expand all/collapse all)

MDAMB-231 cell line

5-50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

MDAMB-231 cell line

50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

MDAMB-231 cell line

25 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

MDAMB-231 cell line

50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

MDAMB-231 cell line

50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

4.3

% Increase

Active

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

4.6

% Increase

Active

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% decrease

55

%

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% decrease

38

%


Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% decrease

11

%

MDAMB-231 cell line

MDAMB-231 cell line

MDAMB-231 cell line

MDAMB-231 cell line

MDAMB-231 cell line

MDAMB-231 cell line

MDAMB-231 cell line

MDAMB-231 cell line

MDAMB-231 cell line

50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% decrease

41

%

50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

4.6

% increase

Active

25-50 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

Fold-increase

<=

3.22

no unit

5-50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

Fold-increase

3.16

no unit

5-50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

Fold-increase

<=

2.13

no unit

5-50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

Fold-increase

0.99

no unit

5-50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

Fold-increase

1.24

no unit

5-50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% of cells in G0/G1 phase

88.1

%

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

25-50 μmol/l

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details


4

EC50

16.9

μg/ml

Antioxidant

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Guilhon-Simplicio, Fernanda; Machado, Tallita Marques; do Nascimento, Leandro Flores; Souza, Rayanne da Silva; Koolen, Hector Henrique Ferreira; da Silva, Felipe Moura Araújo; Acho, Leonard Domingo Rosales; dos Santos, Adair Roberto Soares; Cos, Paul; Pereira, Maria de Meneses; Lima, Emerson Silva

Phytotherapy Research, 2017 , vol. 31, # 11 p. 1686 - 1693 Title/Abstract Full Text View citing articles Show Details

4.86

IC50

2.34

μg/ml

Antioxidant

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Meka, Bharani; Ravada, Suryachandra Rao; Kancharla, Harikrishna; Golakoti, Trimurtulu

Medicinal Chemistry Research, 2017 , vol. 26, # 12 p. 3106 - 3124 Title/Abstract Full Text View citing articles Show Details

3.75

IC50

0.176

mM

Inhibitor

Aldose reductase [Rattus norvegicus]:Wild

liver

Antidiabetic

Journal of Enzyme Inhibi...

Title/Abstract Full Text View citing articles Show Details

Alim, Zuhal; Kilinç, Namik; Şengül, Bülent; Beydemir, Şükrü

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 , vol. 32, # 1 p. 277 - 284 Title/Abstract Full Text View citing articles Show Details

3.66

Ki

0.219

mM

Inhibitor

Aldose reductase [Rattus norvegicus]:Wild

liver

Antidiabetic

Journal of Enzyme Inhibi...

Title/Abstract Full Text View citing articles Show Details

Alim, Zuhal; Kilinç, Namik; Şengül, Bülent; Beydemir, Şükrü

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 , vol. 32, # 1 p. 277 - 284 Title/Abstract Full Text View citing articles Show Details

3.57

IC50

45.35

μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Ali, Saima; Khan, Muhammad Rashid; Sajid, Moniba

Biomedicine and Pharmacotherapy, 2017 , vol. 95, p. 1853 - 1867 Title/Abstract Full Text View citing articles Show Details

3.73

IC50

31.42

μg/ml

Inhibitor

alphaglucosidase:Wild

Antidiabetic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Şöhretoğlu, Didem; Sari, Suat; Šoral, Michal; Barut, Burak; Özel, Arzu; Liptaj, Tibor

International Journal of Biological Macromolecules, 2018 , vol. 108, p. 81 - 87 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

3.61

MIC

41.7

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

3.21

MIC

104.2

μg/ml

7.8 250

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details


μg/ml

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

250

μg/ml

7.8 250 μg/ml

Antibiotic

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Vu, Thuy Thu; Kim, Hun; Tran, Vu Khac; Vu, Hoang Dinh; Hoang, Tien Xuan; Han, Jae Woo; Choi, Yong Ho; Jang, Kyoung Soo; Choi, Gyung Ja; Kim, Jin-Cheol

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181499 Title/Abstract Full Text View citing articles Show Details

3.89

IC50

0.13

mM

0.01 2 mM

Antioxidant

AMB Express, 2017 , vol...

Title/Abstract Full Text View citing articles Show Details

Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol

AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details

3.3

% Inhibition

Active

0.5 - 5 mM

Antiperoxidant

AMB Express, 2017 , vol...

Title/Abstract Full Text View citing articles Show Details

Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol

AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details

2.7

Ki

1.98

mM

Inhibitor

Tyrosinase [mushroom]:Wild

<= 10 mM

AMB Express, 2017 , vol...

Title/Abstract Full Text View citing articles Show Details

Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol


AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details

% production

130

%

Hs 68 cell line

10 100 μM

AMB Express, 2017 , vol...

Title/Abstract Full Text View citing articles Show Details

Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol

AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details

% production

175

%

Hs 68 cell line

10 100 μM

AMB Express, 2017 , vol...

Title/Abstract Full Text View citing articles Show Details

Nam, Seung-Hee; Park, Jeongjin; Jun, Woojin; Kim, Doman; Ko, Jin-A; Abd El-Aty; Choi, Jin Young; Kim, Do-Ik; Yang, Kwang-Yeol

AMB Express, 2017 , vol. 7, # 1 art. no. 224 Title/Abstract Full Text View citing articles Show Details

4.88

IC50

2.25

mg/l

Antioxidant

3 Biotech, 2018 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Yuan, Shengliang; Duan, Zhihong; Lu, Yingnian; Ma, Xiaoli; Wang, Sheng

3 Biotech, 2018 , vol. 8, # 1 art. no. 8 Title/Abstract Full Text View citing articles Show Details

3.23

IC50

100

mg/l

Antioxidant

3 Biotech, 2018 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Yuan, Shengliang; Duan, Zhihong; Lu, Yingnian; Ma, Xiaoli; Wang, Sheng

3 Biotech, 2018 , vol. 8, # 1 art. no. 8 Title/Abstract Full Text View citing articles Show Details

2.83

IC50

250

mg/l

Antioxidant

3 Biotech, 2018 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Yuan, Shengliang; Duan, Zhihong; Lu, Yingnian; Ma, Xiaoli; Wang, Sheng

3 Biotech, 2018 , vol. 8, # 1 art. no. 8 Title/Abstract Full Text View citing articles Show Details

Fold-increase

2.95

no unit

Jurkat cell line

10 μM

Antineoplastic

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details

Fold-increase

3.4

no unit

Jurkat cell line

30 μM

Antineoplastic

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details

Fold-increase

4.5

no unit

Jurkat cell line

50 μM

Antineoplastic

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details

Fold-increase

6.5

no unit

Jurkat cell line

80 μM

Antineoplastic

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details


5

% Increase

Active

Jurkat cell line

10 - 50 μM

Antineoplastic

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details

4.1

% Increase

Active

Jurkat cell line

80 μM

Antineoplastic

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Sourani, Zahra; Shirzad, Hedayatollah; Shirzad, Moein; Pourgheysari, Batoul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1045 - 1054 Title/Abstract Full Text View citing articles Show Details

4.6

IC50

25.16

μM

<= 10 μg/ml

Antioxidant

Journal of Chromatograph...

Title/Abstract Full Text View citing articles Show Details

Peng, Jinming; Li, Kaikai; Zhu, Wei; Deng, Xiangyi; Li, Chunmei

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018 , vol. 1072, p. 78 - 85 Title/Abstract Full Text View citing articles Show Details

Reduction potential

1.91

no unit

Antioxidant

Journal of Chromatograph...

Title/Abstract Full Text View citing articles Show Details

Peng, Jinming; Li, Kaikai; Zhu, Wei; Deng, Xiangyi; Li, Chunmei

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018 , vol. 1072, p. 78 - 85 Title/Abstract Full Text View citing articles Show Details

3.7

IC50

197.92

μM

<= 200 μg/ml

Antioxidant

15-240 μg/ml

Antioxidant

Journal of Chromatograph...

Title/Abstract Full Text View citing articles Show Details

Peng, Jinming; Li, Kaikai; Zhu, Wei; Deng, Xiangyi; Li, Chunmei

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018 , vol. 1072, p. 78 - 85 Title/Abstract Full Text View citing articles Show Details

4.05

% increase

Active

liver

liver cell

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details

4.05

% increase

Active

liver

liver cell

15-240 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details

4.05

% increase

Active

liver

liver cell

15-240 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details

3.99

IC50

17.34

μg/ml

liver

liver cell

15-240 μg/ml

Antioxidant

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details

Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details

4.5

IC50

5.43

μg/ml

liver

liver cell

15-240 μg/ml

Biomedicine and Pharmaco...

Title/Abstract Full Text View citing articles Show Details


Erukainure, Ochuko L.; Oyebode, Olajumoke A.; Sokhela, Mxolisi K.; Koorbanally, Neil A.; Islam, Md. Shahidul

Biomedicine and Pharmacotherapy, 2017 , vol. 96, p. 1065 - 1074 Title/Abstract Full Text View citing articles Show Details

6.52

% Increase

Active

LHCNM2 cell line

0.3 - 1 μM

Antioxidant

PeerJ, 2017 , vol. 2017...

Title/Abstract Full Text View citing articles Show Details

Najjar, Fadia; Rizk, Francine; Carnac, Gilles; Nassar, Rim; Jabak, Sara; Sobolev, Anatoly Petrovich; Saada, Yara Bou; El Sabban, Marwan; Hamade, Aline

PeerJ, 2017 , vol. 2017, # 12 art. no. E4144 Title/Abstract Full Text View citing articles Show Details

% Inhibition

93.11

%

Antioxidant

PLoS ONE, 2018 , vol. 1...

Title/Abstract Full Text Show Details

Antioxidant

PLoS ONE, 2018 , vol. 1...

Title/Abstract Full Text Show Details

Antioxidant

Nature Communications, 2...

Title/Abstract Full Text View citing articles Show Details

Rasheed, Saima; Sánchez, Sara S.; Yousuf, Sammer; Honoré, Stella M.; Choudhary, M. Iqbal

PLoS ONE, 2018 , vol. 13, # 1 art. no. E0190509 Title/Abstract Full Text Show Details

4.63

IC50

23.34

μM

Rasheed, Saima; Sánchez, Sara S.; Yousuf, Sammer; Honoré, Stella M.; Choudhary, M. Iqbal

PLoS ONE, 2018 , vol. 13, # 1 art. no. E0190509 Title/Abstract Full Text Show Details

%

100

%

Faissner, Simon; Mishra, Manoj; Kaushik, Deepak K.; Wang, Jianxiong; Fan, Yan; Silva, Claudia; Rauw, Gail; Metz, Luanne; Koch, Marcus; Yong, V. Wee

Nature Communications, 2017 , vol. 8, # 1 art. no. 1990 Title/Abstract Full Text View citing articles Show Details

2.13

MIC

1.25

mg/ml

Antifungal

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details

2.44

MIC

0.625

mg/ml

Antifungal

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details

1.83

MIC50

2.5

mg/ml

Antifungal

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details

2.49

MIC90

5

mg/ml

Antifungal

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details

1.23

% decrease

Active

10 mg/ml

Antibiofilm

PLoS ONE, 2017 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Teodoro, Guilherme Rodrigues; Gontijo, Aline Vidal Lacerda; Borges, Aline Chiodi; Tanaka, Márcia Hiromi; Lima, Gabriela De Morais Gouvêa; Salvador, Marcos José; Koga-Ito, Cristiane Yumi

PLoS ONE, 2017 , vol. 12, # 7 art. no. E0181199 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

0.5

mg/ml

Antibiotic

Applied Microbiology and...


Title/Abstract Full Text Show Details

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.63

MBC

4

mg/ml

Antibiotic

Applied Microbiology and...

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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

MBIC

2

mg/ml

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

MBEC

8

mg/ml

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1

% Inhibition

13.27

%

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.3

% Inhibition

36.77

%

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.62

% Inhibition

70.83

%

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.67

% Inhibition

84.53

%

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.45

% Inhibition

86.83

%

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.83

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.53

% decrease

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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846


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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.93

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.63

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.83

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.53

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.23

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.93

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.63

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.23

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.93

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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

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1.63

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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

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1

% decrease

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Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1

% decrease

Not active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.83

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.93

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.83

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.93

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.83

% increase

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.93

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

2.83

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details

1.93

% decrease

Active

Kang, Jiamu; Li, Qianqian; Liu, Liu; Jin, Wenyuan; Wang, Jingfan; Sun, Yuyang

Applied Microbiology and Biotechnology, 2018 , vol. 102, # 4 p. 1837 - 1846 Title/Abstract Full Text Show Details


Qualitative Information 1 of 515

Effect

Antibiotic

Biological material

Gardnerella vaginalis

Assay Description

2 of 515

3 of 515

4 of 515

5 of 515

Bioassay : EXAMPLE 6 The ability of the vaginal treatment composition of the present invention to inhibit and/or treat vaginal infection was demonstrated. Initially, eight (8) solutions were formed as set forth below in Table 4. ; Samples 1-2 were prepared by dissolving the KELCOGEL® (0.07 grams) and/or xylitol

Results

average plate count=3.43*10E4

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2007/26074 A1, 2007 ; Title/Abstract Full Text Show Details

Effect

Antiviral

Biological material

human

Assay Description

Effect : anti-viral Species : Human papillomavirus (HPV) 16/18 Example 4. Drug screening through quantitative fluorescent PCR analysis Samples The micro emulsions obtained in Example 1 were used as test samples, and saline water was used as the control. HPV samples: condyloma acuminata samples were taken from clinical patients. The samples were washed with saline

Results

treatment with the title compound at 50μl micro emulsion effectively and rapidly eliminated the number of human papillomavirus (HPV) 16/18 from 1.40E5 (control) to 0copies/ml

Citation

SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antiviral

Biological material

human

Assay Description

Effect : anti-viral Species : Human papillomavirus (HPV) 6/11 Example 4. Drug screening through quantitative fluorescent PCR analysis Samples The micro emulsions obtained in Example 1 were used as test samples, and saline water was used as the control. HPV samples: condyloma acuminata samples were taken from clinical patients. The samples were washed with saline

Results

treatment with the title compound at 50μl micro emulsion effectively and rapidly eliminated the number of human papillomavirus (HPV) 6/11 from 1.45E6 (control) to 0copies/ml

Citation

SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

human

Assay Description

Effect : adverse effect Example 5. Clinical use of hydroxybenzoic acid ester in treating condyloma acuminata Diagnosis standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of

Results

treatment with the title compound did not cause any obvious skin irritation however some patients ocassionally experienced a burning sense

Citation

SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

human


6 of 515

7 of 515

8 of 515

Assay Description

Effect : condyloma acuminata; effect on Example 5. Clinical use of hydroxybenzoic acid ester in treating condyloma acuminata Diagnosis standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of

Results

treatment with the title compound showed that in 50 qualified patients, 2 had recovered within 1-4 days, obvious effects were seen in 3 (1-4 days) and 1 (5-8 days) patient, 4 patients had improved effect

Citation

SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : HBeAg secretion; inhibition of Bioassay : liver 2.2.15 cells transfected by hepatitis B virus (HBV) DNA Example 6. Inhibition effect of hydroxybenzoic acid ester analogue on secretion of HBsAg by hepatitis B 2.2.15 cell line Experiment materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological Sciences

Results

treatment with the title compound at 2μmol/ml inhibited the rate of HBeAg secretion measured as 9.40% inhibition rate (control=0%)

Citation

SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : HBsAg secretion; inhibition of Bioassay : liver 2.2.15 cells transfected by hepatitis B virus (HBV) DNA Example 6. Inhibition effect of hydroxybenzoic acid ester analogue on secretion of HBsAg by hepatitis B 2.2.15 cell line Experiment materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological Sciences

Results

treatment with the title compound at 2μmol/ml inhibited the rate of HBsAg secretion measured as 8.83% inhibition rate (control=0%)

Citation

SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE and

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antimutagenic

Assay Description

9 of 515

10 of 515

Target : Salmonella typhimurium TA 100 Bioassay : inhibition of direct-acting mutagenicity of 4-NQO 4-nitroquinoline (4-NQO) as mutagenic agent; standard plate incorporation assay; 37 deg C

Citation

De Flora; Rosenkranz; Klopman

Mutagenesis, 1994 , vol. 9, # 1 p. 39 - 45 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; examination of Bioassay : developing, lignifying xylem; Concanavalin-A bound fraction of xylem extract response of xylem oxidase activity (OA) to title comp. as effector; OA measured against 2,2'-azinobis(3ethylbenzothiazoline-6-sulfonic acid (ABTS

Results

almost complete inhibition of OA in presence of title comp. to 3.3 percent of control value

Citation

Deighton, Nigel; McDougall, Gordon J.

Phytochemistry, 1998 , vol. 48, # 4 p. 601 - 606 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; examination of Bioassay : in vitro; enzyme activity for title comp. assayed according to spectrophotometric procedure; sodium acetate buffer, pH 4.0; 25 deg C; increase in absorbance of oxidation product measured for 3 min

Citation

Paul, Beena; Gowda, Lalitha R.

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 9 p. 3839 - 3846 Title/Abstract Full Text View citing articles Show Details


11 of 515

Effect Assay Description

12 of 515

13 of 515

14 of 515

15 of 515

16 of 515

Target : Escherichia coli strain WP2mutT Bioassay : changed color from purple to yellow due to growth of spontaneous trp+ revertants in culture indicated that spontaneous mutation was not suppressed by title comp.; suppressive ability represented by number of trp+ revertant; control to water sample Mut-Test: 0.4 ml of culture of strain WP2mutT with high spontaneous mutation, 0.25 mg/l of triptophan, 5 mg/l of bromocresol purple (as indicator), 0.4 ml of title comp. solution; incubation at 37 deg C; conc. dependence investigated

Citation

Strange, Richard C.; Spiteri, Monica A.; Ramachandran, Sudarshan; Fryer, Anthony A.

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2001 , vol. 482, # 1-2 p. 21 - 26 Title/Abstract Full Text View citing articles Show Details

Results

inhibit effect on glutathione S-transferase and glutathion reductase activities

Citation

Iio; Kawaguchi; Sakota; Otonari; Nitahara

Bioscience, Biotechnology and Biochemistry, 1993 , vol. 57, # 10 p. 1678 - 1680 Title/Abstract Full Text View citing articles Show Details

Results

inhibitory effect on mushroom tyrosinase, IC 50, mM: 5.91 (spectrophometric method), 16.5 (polarographic method); mixed type of inhibition, inhibition dissociation constant Ki 1.10 mM (spectrophotometric method), 9.69 mM (polarographic method)

Citation

Kermasha, Selim; Goetghebeur, Mireille; Monfette, Alan; Metche, Maurice; Rovel, Bernard

Phytochemistry (Elsevier), 1993 , vol. 34, # 2 p. 349 - 354 Title/Abstract Full Text View citing articles Show Details

Results

appearance of laccase activity

Citation

Viterbo, Ada; Yagen, Boris; Mayer, Alfred M.

Phytochemistry (Elsevier), 1993 , vol. 34, # 1 p. 47 - 50 Title/Abstract Full Text View citing articles Show Details

Results

effect on the growth of pollen tube of Camellia japonica

Citation

Ozawa; Takeshita; Negishi; Imagawa

Bioscience, Biotechnology and Biochemistry, 1993 , vol. 57, # 12 p. 2122 - 2126 Title/Abstract Full Text View citing articles Show Details

Effect

Antifeedant

Assay Description

17 of 515

Antimutagenic

Target : Malacosoma disstria Hubner, forest tent caterpillar Bioassay : leaf disks were photocopied; the percentage of each disk remaining was determined with a Image Analyser; the antifeedant index for each plate was calculated egg bands collected from trembling aspen trees from Cochrane and Thunder Bay, Ontario, Canada; larvae were reared in envirom. chambers at 21 deg C, 80 percent rel. chum., 16L:8D; second leaf disk assay method; 5 newly molted fourth-instar larvae; 24-h test

Results

antifeedant index 33.7 percent

Citation

Abou-Zaid; Helson; Nozzolillo; Arnason

Journal of chemical ecology, 2001 , vol. 27, # 12 p. 2517 - 2527 Title/Abstract Full Text View citing articles Show Details

Effect

Immunostimulant

Biological material

RAW 264.7 cell line

Assay Description

Bioassay : expression profiles compared with those mediated by IFN-γ and LPS; iNOS: inducible NO synthase; IL: interleukin; IFN: interferon; TNF: tumor necrosis factor; RT-PCR: reverse-transcription polymerase chain reaction; LPS: lipopolysacchride expression of iNOS and cytokine IL, IFN, TNF transcripts simulated with title comp. in non-infected and Leishmania-infected test cells studied using RT-


PCR reaction; PCR products separated on agarose gel and quantified by densitometric analysis

18 of 515

19 of 515

Results

results given as percent density of iNOS and cytokine IL-1, IL-12, IL-18, TNF, INF-α, INF-γ in noninfected and infected test cells relative to hypoxanthin-guanine-phosphoribosyl transferase (HGPRT) mRNA defined as 100 percent

Citation

Kolodziej, Herbert; Kiderlen, Albrecht F.

Phytochemistry, 2005 , vol. 66, # 17 SPEC. ISS. p. 2056 - 2071 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |transmitter release; inhibition of Target : human aortic vascular smooth muscle cells Bioassay : vehicle control; PDGFAB: platelet-derived growth factorAB; VEGF: vascular endothelial growth factor cells were exposed to title comp. for 30 min; incubation with PDGFAB (30 ng/ml) for 24 h; VEGF release into medium; immunoassay

Results

title comp. increased basal release of VEGF, but did not change stimulatoty effect of PDGFAB on VEGF level (figure)

Citation

Oak; Bedoui; Madeira; Chalupsky; Schini-Kerth

British Journal of Pharmacology, 2006 , vol. 149, # 3 p. 283 - 290 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

20 of 515

Citation

Oak; Bedoui; Madeira; Chalupsky; Schini-Kerth

British Journal of Pharmacology, 2006 , vol. 149, # 3 p. 283 - 290 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

21 of 515

Target : human aortic vascular smooth muscle cells Bioassay : vehicle control; PDGFAB: platelet-derived growth factorAB; EPR: electron paramagnetic resonance; ROS: reactive oxygen species; TEMPONE-H: 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine; reference comp.: superoxide dismutase cells were treated with title comp. for 30 min; incubation with PDGFAB (30 ng/ml) for 24 h; direct ROS-scavenging activity; EPR-spin trapping method with TEMPONE-H and potassium superoxide

Results

title comp. reduced ROS level stimulated by PDGFAB; reference comp. had similar effect (figure)

Citation

Oak; Bedoui; Madeira; Chalupsky; Schini-Kerth

British Journal of Pharmacology, 2006 , vol. 149, # 3 p. 283 - 290 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic

Assay Description

22 of 515

Target : human aortic vascular smooth muscle cells Bioassay : vehicle control; PDGFAB: platelet-derived growth factorAB; DCF: dichlorofluorescein; ROS: reactive oxygen species cells were loaded with 10 μmol/l DCF for 30 min at 37 deg C; treatment with title comp. for 30 min; incubation with PDGFAB (30 ng/ml) for 1 h; generation of ROS was assessed using DCF fluorescence

Target : lymphocytes of human Bioassay : intact cells used as negative controls; mitomycin C-treated cells used as positive controls blood from healthy donors; cultured with comp. alone or in the presence of mitomycin C; metaphases blocked and frequency of sister chromatid exchange determined

Results

title comp. enhanced mitomycin C-induced clastogenicity and alone had no genotoxic activity; tab.

Citation

Stagos, Dimitrios; Spanou, Chrysa; Margariti, Maria; Stathopoulos, Constantinos; Mamuris, Zissis; Kazantzoglou, Georgios; Magiatis, Prokopios; Kouretas, Demetrios

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 13 p. 5246 - 5252 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant


Assay Description

23 of 515

Results

title comp. was effective antioxidant against AAPH-induced microsomal peroxidation; antioxidant synergism with endogenous TOH was due to reduced initiation rate caused by title comp. due to trapping initiating radicals in bulk water phase

Citation

Cai, Yu-Jun; Ma, Lan-Ping; Hou, Li-Fen; Zhou, Bo; Yang, Li; Liu, Zhong-Li

Chemistry and Physics of Lipids, 2002 , vol. 120, # 1-2 p. 109 - 117 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

24 of 515

26 of 515

Target : HIT cells Bioassay : then washed with PBS and challenged with 4E-4 Sigma units glucose oxidase (GO) plus 30 μmol/l metMb in fresh medium for 20 h; 1 μCi/well <3H>thymidine added 18 h before cell harvesting ability to protect cells from H2O2/metmyoglobin (metMb) ferryl stress assessed measuring cell proliferation by <3H>thymidine incorporation assay; 3E5 cells/well; 30 μmol/l metMb; DMEM with 10 percent FCS; 37 deg C; incubated for 24 h

Citation

Lapidot, Tair; Walker, Michael D.; Kanner, Joseph

Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 25 p. 7220 - 7225 Title/Abstract Full Text View citing articles Show Details

Effect

Antiproliferative

Assay Description

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Target : Wistar rat liver microsomes Bioassay : 37 deg C; title comp. added before or after AAPH initiation; synergism with endogenous α-tocopherol (TOH) studied in vitro; effect on free radical-initiated microsomal peroxidation evaluated by oxygen uptake and malondialdehyde formation measurements; 8 mmol/l 2,2'-azobis(2-amidinopropane hydrochloride) (AAPH) used as initiator; potassium phosphate buffer, pH 7.4

Target : HIT cells Bioassay : without or with 30 μmol/l metmyoglobin added simultaneously with title comp. effect on cell proliferation assessed using <3H>thymidine incorporation assay; 3E5 cells/well; DMEM with 10 percent FCS; 37 deg C; incubated for 20 h; 1 μCi/well <3H>thymidine added 18 h before cell harvesting

Results

title comp. produced significant proliferation inhibition, which was reduced by inclusion of metmyoglobin

Citation

Lapidot, Tair; Walker, Michael D.; Kanner, Joseph

Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 25 p. 7220 - 7225 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : enzyme activity; inhibition of Bioassay : lansoprazole used as reference comp. incubated with title comp. in the presence substrate 2mM ATP at 37 deg C for 30 min; H+,K+-ATPase inhibition assessed by spectrophotometric measurements at 400 nm of released inorganic phosphate

Results

title comp. IC50 132.0 μg/ml (vs. 19.3 μg/ml for lansoprazole)

Citation

Siddaraju; Dharmesh, Shylaja M.

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7377 - 7386 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Biological material

Helicobacter pylori

Assay Description

Bioassay : 10 μg/ml amoxicillin used as reference comp.; 0.9% saline-treated negative controls Gram-negative bacterium obtained by endoscopic samples of ulcer patients; standard agar diffusion method; zone of inhibition around disks placed on inoculated plates measured

Results

title comp. produced zone of inhibition of 14 mm (44% inhibition) vs. 36 mm (78% inhibition) for amoxicillin

Citation

Siddaraju; Dharmesh, Shylaja M.

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7377 - 7386 Title/Abstract Full Text View citing articles Show Details


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Effect

Antibiotic

Biological material

Helicobacter pylori

Assay Description

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Results

title comp.-treated cells changed (similarly to amoxicillin treated ones) from helical form to coccoid form and became necrotic; fig.

Citation

Siddaraju; Dharmesh, Shylaja M.

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7377 - 7386 Title/Abstract Full Text View citing articles Show Details

Effect

Toxic

Assay Description

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inhibition zone diameter was 23 and > 40 mm at 27 and 160 μg, resp. (table)

Citation

Walenciak, Oliver; Zwisler, Walter; Gross, Elisabeth M.

Journal of Chemical Ecology, 2002 , vol. 28, # 10 p. 2045 - 2056 Title/Abstract Full Text View citing articles Show Details

Effect

Toxic

Target : Comamonas sp. Bioassay : closest relative strain characterized; larvae fed with Myriophyllum spicatum or Potamogeton perfoliatus bacteria isolated from gut microbiota of larvae of aquatic moth Acentria ephemerella; title comp. applied to CPS agar plates (alkaline media) incubated with bacteria at 24 deg C for 48 h; inhibition zone diameter determ.

Results

inhibition zone diameter was 13 and > 40 mm at 27 and 160 μg, resp. (table)

Citation

Walenciak, Oliver; Zwisler, Walter; Gross, Elisabeth M.

Journal of Chemical Ecology, 2002 , vol. 28, # 10 p. 2045 - 2056 Title/Abstract Full Text View citing articles Show Details

Effect

Toxic

Biological material

Pseudomonas

Assay Description

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Target : Chryseobacterium sp. Bioassay : closest relative strain characterized; larvae fed with Myriophyllum spicatum; bacteria also isolated from leaves of Potamogeton perfoliatus bacteria isolated from gut microbiota of larvae of aquatic moth Acentria ephemerella or from food plants leaves; title comp. applied to CPS agar plates (alkaline media) incubated with bacteria at 24 deg C for 48 h; inhibition zone diameter determ.

Results

Assay Description

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Bioassay : 10-30 μg/ml amoxicillin used as reference comp.; untreated control cells Gram-negative bacterium obtained by endoscopic samples of ulcer patients; cultured with title comp. at 37 deg C for 6 h; changes in cell morphology assessed by using scanning electron microscopy

Bioassay : closest relative strain characterized; larvae fed with Potamogeton perfoliatus bacteria isolated from gut microbiota of larvae of aquatic moth Acentria ephemerella; title comp. applied to CPS agar plates (alkaline media) incubated with bacteria at 24 deg C for 48 h; inhibition zone diameter determ.

Results

inhibition zone diameter was 26 and > 40 mm at 27 and 160 μg, resp. (table)

Citation

Walenciak, Oliver; Zwisler, Walter; Gross, Elisabeth M.

Journal of Chemical Ecology, 2002 , vol. 28, # 10 p. 2045 - 2056 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Results

Target : Sprague-Dawley rat liver microsomes Bioassay : enzymatic lipid peroxidation (LPO) studied; microsomes incubated with NADPH generating system in the presence or absence of title comp.; pH 7.4, 37 deg C, 30 min; LPO assayed by estimation of thiobarbiturate reacting substances (TBARS) slight effect; 10 μmol/l title comp. inhibited TBARS formation by 7 percent compared to control; diagram given


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Citation

Gyamfi, Maxwell Afari; Aniya, Yoko

Biochemical Pharmacology, 2002 , vol. 63, # 9 p. 1725 - 1737 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

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Target : Sprague-Dawley rat liver microsomes Bioassay : non-enzymatic lipid peroxidation (LPO) studied; microsomes incubated with FeSO4 and ascorbate in the presence or absence of title comp.; pH 7.4, 37 deg C, 20 min; LPO assayed by estimation of thiobarbiturate reacting substances (TBARS)

Results

concentration-dependent effect; 10 μmol/l title comp. inhibited TBARS formation by 7 percent compared to control; diagram given

Citation

Gyamfi, Maxwell Afari; Aniya, Yoko

Biochemical Pharmacology, 2002 , vol. 63, # 9 p. 1725 - 1737 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : pooled microsomes from seven individuals title comp. preincubated with microsomes in the presence or absence of NADPH; then incubated with isocitrate, isocitrate dehydrogenase, MgCl2, NADP and <14C>androstenedione for 10 min at 37 deg C; products separated by TLC; scintillation spectrometry

Results

title comp. significantly inhibited androstenedione 6β-hydroxylase activity (nmol/mg protein/min) from 0.53 and 0.43 to 0.20 and 0.03 in the presence and absence of NADPH, respectively; no inhibition after removal title comp.-derived products

Citation

Stupans; Tan; Kirlich; Tuck; Hayball; Murray

Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; examination of Bioassay : pooled microsomes from seven individuals; effect on CYP content examined title comp. preincubated with microsomes in the presence or absence of NADPH; CO-reduced CYP difference spectra recorded; CYP content evaluated

Citation

Stupans; Tan; Kirlich; Tuck; Hayball; Murray

Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : pooled microsomes from seven individuals; chlorzoxazone 6-hydroxylase activity assayed microsomes preincubated with title comp. in the presence or absence of NADPH for 15 min; then mixture incubated with isocitrate, isocitrate dehydrogenase, MgCl2, NADP and <2-14C>chlorzoxazone for 20 min at 37 deg C

Citation

Stupans; Tan; Kirlich; Tuck; Hayball; Murray

Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : pooled microsomes from seven individuals; ethoxyresorufin-O-deethylase activity assayed microsomes and title comp. preincubated with and without NADPH for 15 min; then mixture incubated with isocitrate, isocitrate dehydrogenase, MgCl2, NADP and ethoxyresorufin for 15 min at 37 deg C; resorufin quantified by fluorescence spectrophotometry

Citation

Stupans; Tan; Kirlich; Tuck; Hayball; Murray

Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild


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Assay Description

Effect : |enzyme; inhib. of Bioassay : pooled microsomes from seven individuals microsomes preincubated with title comp. in the presence or absence of NADPH for 15 min; mixture diluted, substrate and generating system added; 17β-hydroxysteroid dehydrogenase activity determined

Citation

Stupans; Tan; Kirlich; Tuck; Hayball; Murray

Journal of Pharmacy and Pharmacology, 2002 , vol. 54, # 2 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : fibril formation Target : β-amyloid (1-42) Bioassay : PBS; room temp.; incubated for 1 h; aggregation of peptide measured by thioflavin fluorescence assay

Citation

Kim, Hee; Park, Byeoung-Soo; Lee, Kwang-Geun; Cheol, Yong Choi; Sung, Sik Jang; Kim, Young-Ho; Lee, Sung-Eun

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 22 p. 8537 - 8541 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |biotransformation Target : Lactobacillus hilgardii 5w Bioassay : complex FT80 medium, pH 5.0; microaerophilic conditions; 30 deg C; incubated in darkness for 48 h; HPLC analysis of metabolites

Results

title comp., pyrogallol, catechol, protocatechuic acid, p-hydroxybenzoic acid, p-hydroxybenzaldehyde, and p-hydroxybenzyl alcohol were detected in incubation medium Further metabolite(s)

Citation

Alberto, Maria R.; Gomez-Cordoves, Carmen; Manca De Nadra, Maria C.

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 21 p. 6465 - 6469 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : protein; binding to Target : Lactobacillus hilgardii 5w Bioassay : adsorption on cell walls evaluated; ca. 2E8 heat-inactivated cells/ml; complex FT80 medium, pH 5.0; 30 deg C; incubated for 48 h; conc. of title comp. in culture-free supernatant measured

Citation

Alberto, Maria R.; Gomez-Cordoves, Carmen; Manca De Nadra, Maria C.

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 21 p. 6465 - 6469 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : oxygen radical absorbance capacity Bioassay : 2,2'-azobis(2-amidinopropane) dihydrochloride 1 ORAC unit corresponded to the inhibition of declining fluorescence produced by 1 μmol/l of Trolox

Results

ORAC units 1.94 units

Citation

Pfundstein, Beate; El Desouky, Samy K.; Hull, William E.; Haubner, Roswitha; Erben, Gerhard; Owen, Robert W.

Phytochemistry, 2010 , vol. 71, # 10 p. 1132 - 1148 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : oxygen radical

Results

ORAC oxygen radical absorbance capacity 6.4 mmol Trolox equivalent/g

Citation

Huang, Yong-Lin; Tsujita, Takaaki; Tanaka, Takashi; Matsuo, Yosuke; Kouno, Isao; Li, Dian-Peng; Nonaka, Gen-Ichiro

Phytochemistry, 2011 , vol. 72, # 16 p. 2006 - 2014 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative


Bioassay : Ce(SO4)2*4 H2O CERAC assay; CERAC: Ce(IV)-based reducing capacity; TEAC: trolox equivalent antioxidant capacity; TEAC coefficient: ratio of slope of spectrofluorometric titration curve of tested antioxidant to that of trolox; TEAC coefficient determined by fluorescence method or absorptimetric assay

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Results

TEAC coefficient 2.02 - 3.27

Citation

Ozyurt, Dilek; Demirata, Birsen; Apak, Resat

Journal of Fluorescence, 2011 , vol. 21, # 6 p. 2069 - 2076 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : CuCl2

CUPRAC assay; CUPRAC: CUPric reducing antioxidant capacity; TEAC: trolox equivalent antioxidant capacity; TEAC coefficient: ratio of slope of spectrofluorometric titration curve of tested antioxidant to that of trolox

Results

TEAC coefficient 2.6

Citation

Ozyurt, Dilek; Demirata, Birsen; Apak, Resat

Journal of Fluorescence, 2011 , vol. 21, # 6 p. 2069 - 2076 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : radical scavenging Bioassay : ABTS TEAC: trolox equivalent antioxidant capacity; TEAC coefficient: ratio of slope of spectrofluorometric titration curve of tested antioxidant to that of trolox

Results

TEAC coefficient 3

Citation

Ozyurt, Dilek; Demirata, Birsen; Apak, Resat

Journal of Fluorescence, 2011 , vol. 21, # 6 p. 2069 - 2076 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Biological material

Salmonella enterica serovar Typhimurium

Assay Description

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Citation

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Biological material

Bacteroides fragilis

Assay Description

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Bioassay : growth inhibition test; spectrophotometry

Bioassay : growth inhibition test; spectrophotometry

Citation

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Biological material

Clostridium perfringens


Assay Description

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Citation

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Assay Description

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Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Target : Enterobacter cloacae ATCC 13047 Bioassay : growth inhibition test; spectrophotometry

Citation

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Assay Description

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Target : Clostridium paraputrificum ATCC 25780 Bioassay : growth inhibition test; spectrophotometry

Citation

Assay Description

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Target : Clostridium clostridiiforme ATCC 25537 Bioassay : growth inhibition test; spectrophotometry

Citation

Assay Description

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Target : Bifidobacterium infantis ATCC 15697 Bioassay : growth inhibition test; spectrophotometry

Citation

Assay Description

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Bioassay : growth inhibition test; spectrophotometry

Target : Lactobacillus acidophilus ATCC 4356 Bioassay : growth inhibition test; spectrophotometry

Citation

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Assay Description

Target : Salmonella typhimurium YG1041


Bioassay : growth inhibition test; spectrophotometry

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Citation

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Biological material

Escherichia coli

Assay Description

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Bioassay : growth inhibition test; spectrophotometry

Citation

Chung; Lu; Chou

Food and Chemical Toxicology, 1998 , vol. 36, # 12 p. 1053 - 1060 Title/Abstract Full Text View citing articles Show Details

Results

contents in stems of in vitro grown shoots

Citation

Scalbert, Augustin; Monties, Bernard; Favre, Jean-Michel

Phytochemistry (Elsevier), 1988 , vol. 27, # 11 p. 3483 - 3488 Title/Abstract Full Text View citing articles Show Details

Results

enzyme inhibitory effect on grape catechol oxidase

Citation

Gunata, Yusuf Z.; Sapis, Jean-Claude; Moutounet, Michel

Phytochemistry (Elsevier), 1987 , vol. 26, # 6 p. 1573 - 1576 Title/Abstract Full Text View citing articles Show Details

Results

no significant inhibition of α-amylase, ID50: > 1000 μM

Citation

Hara, Yukihiko; Honda, Miwa

Agricultural and Biological Chemistry, 1990 , vol. 54, # 8 p. 1939 - 1945 Title/Abstract Full Text Show Details

Assay Description

Effect : tumor necrosis factor alpha (TNF-α) biosynthesis; inhibition of Target : keratinocytes of human Bioassay : [Experimental example 10] Measurement of inhibition effect on biosynthesis of tumor necrosis factor alpha (TNF-α) by UV irradiation Human keratinocytes were cultured in a 12-well plate type incubator at a concentration of 104. The plate was irradiated by UV-B at 30mJ/cπf. The media

Results

10μM of the title compound produced 36% TNF-α as compared to 100% of the UV control

Citation

AMOREPACIFIC CORPORATION

Patent: WO2007/29982 A1, 2007 ; Title/Abstract Full Text Show Details

Assay Description

Effect : type I collagenase (MMP-1) biosynthesis; effect on Target : fibroblasts of human Bioassay : [Experimental example 11] Measurement of inhibition effect on biosynthesis of Type I collagenase (MMP-I) by UV irradiation Human fibroblasts isolated from the skin of new born baby were cultured in a48-well plate type incubator at a concentration of 104. after 24 hours, the plate was irradiated

Results

10 ppm of the title compound produced 52% type IV collagen (w/ UV-A irradiated group) and 89% type IV collagen (w/ UV-A+TNF-α treated group) as compared to 100% and 124% of the control, respectively

Citation

AMOREPACIFIC CORPORATION

Patent: WO2007/29982 A1, 2007 ; Title/Abstract Full Text Show Details

Target

Peroxisome proliferator-activated receptor, alpha:Wild


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Assay Description

Effect : Peroxisome Proliferator Activated Receptor-α (PPAR-α) activation; effect on Bioassay : [Experimental example 9] Test of activation of PPAR-α (Peroxisome Proliferator Activated Receptor-alpha) playing a role in promotion of differentiation/inhibition of multiplication of dermal cells and promotion of lipid biosynthesis and prevention of inflammationMonkey kidney epithelial cell line

Results

1.3-1.7 PPAR-α activity was measured at 10-100μM of the title compound

Citation

AMOREPACIFIC CORPORATION

Patent: WO2007/29982 A1, 2007 ; Title/Abstract Full Text Show Details

Target

lipase:Wild

Assay Description

Effect : lipase; inhibition of Bioassay : Lipase activity measurement was carried out by using oleic acid ester of fluorescence 4-methylumbelliferone (4-UMO) as a substrate, and measuring the fluorescence of 4-methylumbelliferone produced by reaction. In the measurement, 13 mM Tris-HCl containing 150 mM NaCl and 1.36 mM CaCl2 was

Citation

SUNTORY LIMITED

Patent: EP1783136 A1, 2007 ; Title/Abstract Full Text Show Details

Results

active inhibitor of the nitrite oxidation of oxyhemoglobin

Citation

Kostenko, L. Kh.; Rozantsev, E. G.; Savel'ev, V. A.

Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 12 p. 904 - 907Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 12 p. 1458 - 1461 Title/Abstract Full Text View citing articles Show Details

Results

gastroprotective activity, adrenoprolonging action (rats and mice)

Citation

Barnaulov, O. D.

Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 6 p. 427 - 430Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 6 p. 689 - 692 Title/Abstract Full Text View citing articles Show Details

Biological material

Mus musculus RAW 264.7 cell line

Assay Description

Effect : gene expression; inhibition of Bioassay : control: vehicle; NF: nuclear factor; LPS: lipopolysaccharide; cells transfected with NF-κB luciferase reporter gene and pSV-β-Galactosidase Control Vector; reference comp.: oleanolic acid, ursolic acid, pyrrolidine dithiocarbamate (NF-κβ inhibitor) cultured in DMEM at 37 deg C; treated for 2 h with title comp. prior to 23 h treatment with LPS; after 24 h, cells lysed and assayed for luciferase and β-galactosidase activities using Bright-Glo Luciferase Assay System and Beta-Glo Assay System

Results

title comp. inhibited lipopolysaccharide-induced NFκB promoter activity (figure); effect was significant at dose of 300 μg/ml

Citation

Huang, Tom H. W.; Yang, Qinglin; Harada, Masaki; Li, George Q.; Yamahara, Johji; Roufogalis, Basil D.; Li, Yuhao

Journal of Cardiovascular Pharmacology, 2005 , vol. 46, # 6 p. 856 - 862 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

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Target : Salmonella typhimurium TA980 Bioassay : mutagens used: 2-nitrofluorene, 2-nitro-p-phenylenediamine, 3-nitro-and 4-nitro-o-phenylenediamines, 4,4'-dinitro-2-biphenylamine, 1-nitropyrene, 1,3-dinitropyrene, benzidine, 4aminobiphenyl, 3,3',4,4'-tetraaminobiphenyl, N,N,N',N'-tetramethylbenzidine Ames test; standard incorporation and preincubation procedures; in the abs. and pres. of S9 mix; mutagens added and preincub. for 30 min before plating

Citation

Grice; Goldsmith

Food and Chemical Toxicology, 2000 , vol. 38, # SUPPL. 2 p. 1 - 6 Title/Abstract Full Text View citing articles Show Details

Effect

Mutagenic

Biological material

Salmonella enterica serovar Typhimurium


Assay Description

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Citation

Grice; Goldsmith

Food and Chemical Toxicology, 2000 , vol. 38, # SUPPL. 2 p. 1 - 6 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : in vitro; potassium phosphate buffer (pH 6.3); maltose as substrate

Results

inhibitory activity of title comp. 4.3 percent

Citation

Toda; Kawabata; Kasai

Bioscience, biotechnology, and biochemistry, 2001 , vol. 65, # 3 p. 542 - 547 Title/Abstract Full Text Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : in vitro; potassium phosphate buffer (pH 6.3); sucrose as substrate

Results

inhibitory activity of title comp. 8.12

Citation

Toda; Kawabata; Kasai

Bioscience, biotechnology, and biochemistry, 2001 , vol. 65, # 3 p. 542 - 547 Title/Abstract Full Text Show Details

Effect

Immunostimulant

Assay Description

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Bioassay : Ames test; standard preincubation procedures in the abs. and pres. of liver S9 mix; 2-aminofluorene, 2-nitrofluorene and N-methyl-N-nitro-N'-nitrosoguanidine as reference comp.

Target : murine macrophage (RAW 264.7) cells Bioassay : tumor necrosis factor (TNF-)α, interferon (IFN) release determined using murine L929 fibroblast cytotoxicity assays cells incub. with title comp. in R10 medium (37 deg C; 5 percent CO2, 48 h <NO>; 6 percent CO2, 18 h <TNF-α>; 48 h <IFN>); NO production measured by the Griess assay

Results

at 50 mg/l: 54.0 μmol/l NO produced; EC50, μg/ml: 25.0 <TNF-α>; 0.7 <IFN>

Citation

Kolodziej; Kayser; Kiderlen; Ito; Hatano; Yoshida; Foo

Planta Medica, 2001 , vol. 67, # 9 p. 825 - 832 Title/Abstract Full Text View citing articles Show Details

Biological material

RAW 264.7 cell line

Assay Description

Effect : |metabolic Bioassay : 5 percent CO2 atmosphere; NO production measured using Griess reagent in vitro; inhibition of LPS/IFN-γ-stimulated NO production assayed; 6E5 cells/well preincubated with title comp. for 1 h before stimulation with 10 ng/mL LPS and 10-50 units/mL IFN-γ; activated cells were further incubated for 24 h; DMEM; 37 deg C

Results

title comp. inhib. NO production in a dose-dependent manner; nitrite conc. (μM)/dose (μM): 49.7/16, 53.6/31, 46.9/63, 43.8/125, 34.0/250, and 13.4/500 (control: 46.2); inhib. effect for 250 μM dose: ca. 27 percent and for 500 μM dose: ca.

Citation

Wang; Mazza

Journal of agricultural and food chemistry, 2002 , vol. 50, # 4 p. 850 - 857 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

RAW 264.7 cell line

Assay Description


Bioassay : in vitro; 6E5 cells/well incubated with title comp. for 24 h; viability of cells determined using MTT assay; DMEM; 37 deg C; 5 percent CO2 atmosphere

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Results

title comp. showed cytotoxicity only at 125 and 500 μmol/l (cell viability: 97 and 20 percent, respectively)

Citation

Wang; Mazza

Journal of agricultural and food chemistry, 2002 , vol. 50, # 4 p. 850 - 857 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : transcriptional factor; modulation of Target : MTLN cells Bioassay : then title comp. added and incubated for further 6 h; luciferase activity determined by luminescence method; PMA: 12-O-tetradecanoyl phorbol-13-acetate; AP-1: activator protein-1 in vitro; effect on AP-1 stimulation evaluated; cells derived from MCF-7 cells stably transfected with luciferase and neomycin resistance gene; 1.25E5 cells/ml; phenol red DMEM with 5 percent FCS; humidified 5 percent CO2; 37 deg C; preincubated for 48 h

Citation

Maggi-Capeyron; Ceballos; Cristol; Delbosc; Le Doucen; Pons; Leger; Descomps

Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 11 p. 5646 - 5652 Title/Abstract Full Text View citing articles Show Details

Effect

Antiallergic

Assay Description

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Target : RBL-2H3 cells Bioassay : washed and suspended in siraganian buffer, pH 7.2; incubated with title comp. for 10 min at 37 deg; then 10 μg/ml DNP-BSA added for 10 min to stimulate degranulation; amount of βhexosaminidase released determined; DNP-BSA: dinitrophenylated BSA in vitro; inhibition of DNP-BSA-induced β-hexosaminidase (degranulation masker of mast cells) release from anti-DNP IgE-sensitized cells evaluated; 2E5 cells/well; MEM with 10 percent FCS; 5 percent CO2; 37 deg C; sensitized overnight with 0.45 μg/ml anti-DNP IgE

Results

at 10/30/100 μmol/l title comp. inhibited β-hexosaminidase release by -4.5/-3.3/-6.5 percent

Citation

Matsuda, Hisashi; Morikawa, Toshio; Tao, Jing; Ueda, Kazuho; Yoshikawa, Masayuki

Chemical and Pharmaceutical Bulletin, 2002 , vol. 50, # 2 p. 208 - 215 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : hydrogen peroxide

Results

scavenging activity <= 59.2 percent

Citation

Cho, Young-Sook; Kim, Se-Kwon; Ahn, Chang-Bum; Je, Jae-Young

Carbohydrate Polymers, 2011 , vol. 83, # 4 p. 1617 - 1622 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : free radical scavenging Target : 2,2-diphenyl-1-picrylhydrazyl radical Bioassay : 2,2-diphenyl-1-picrylhydrazyl radical

Results

scavenging activity <= 49.03 percent

Citation

Cho, Young-Sook; Kim, Se-Kwon; Ahn, Chang-Bum; Je, Jae-Young

Carbohydrate Polymers, 2011 , vol. 83, # 4 p. 1617 - 1622 Title/Abstract Full Text View citing articles Show Details

Effect

Oxidant

Assay Description

Effect : CuI-mediated DNA damage Bioassay : plasmid DNA pBSSK gel electrophoresis

Results

increase rate 11.9 percent


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Citation

Perron, Nathan R.; Garcia, Carla R.; Pinzon, Julio R.; Chaur, Manuel N.; Brumaghim, Julia L.

Journal of Inorganic Biochemistry, 2011 , vol. 105, # 5 p. 745 - 753 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : carbon-centered free radical scavenging Bioassay : AAPH AAPH: 2,2'-azobis(2-amidinopropane).HCl

Results

scavenging capacity 100 percent

Citation

Pasanphan, Wanvimol; Buettner, Garry R.; Chirachanchai, Suwabun

Carbohydrate Research, 2010 , vol. 345, # 1 p. 132 - 140 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : 2,2'-azo-bis(2-amidinopropane) dihydrochloride Triton X-100 used as micelles; oxygen radical absorbance capacity relative to Trolox (ORAC-PGR) = 1

Results

ORAC-PGR oxygen radical absorbance capacity 11.7

Citation

Romero, Max; Rojano, Benjamin; Mella-Raipan, Jaime; Pessoa-Mahana, Carlos David; Lissi, Eduardo; Lopez-Alarcon, Camilo

Molecules, 2010 , vol. 15, # 9 p. 6152 - 6167 Title/Abstract Full Text View citing articles Show Details

Biological material

Caco-2

Assay Description

Effect : transport of fluorescein; examination of Bioassay : permeation rate of fluorescein in the absence (control) and presence of title comp. calculated; relative permation expressed as percentage of value from control study Caco-2 monolayers prepared; solution contain. 0.1 mmol/l fluorescein (pH 6.0, 37 deg C) and title comp. added to apical side of insert; cells incub. at 37 deg C for 40 min; amonut of fluorescein permeated to basolateral side evaluated by fluorescence

Results

relative permeation of fluorescein in test cell monolayers: 109.5 percent of control

Citation

Konishi, Yutaka; Kubo, Kazuo; Shimizu, Makoto

Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 9 p. 2014 - 2017 Title/Abstract Full Text Show Details

Effect

Antiviral

Biological material

human

Assay Description

Effect : anti-viral Species : Human papillomavirus 6/11 Example 4 Drug Screening Through Quantitative Fluorescent PCR Analysis Samples The test compounds listed in Table 1 below were prepared as micro emulsions as described in Example 1. Saline water was used as the control. Methyl 2,3,4-trihydroxybenzoate was prepared as follows: 10 g of 2,3,4-trihydroxybenzoic

Results

no Human papillomavirus HPV 6/11 virus remained 24 hours after treatment with 50 µl micro emulsion containing 10 % of title compound

Citation

QIN, Weihua

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antiviral

Biological material

human


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Assay Description

Effect : anti-viral Species : Human papillomavirus 6/18 Example 4 Drug Screening Through Quantitative Fluorescent PCR Analysis Samples The test compounds listed in Table 1 below were prepared as micro emulsions as described in Example 1. Saline water was used as the control. Methyl 2,3,4-trihydroxybenzoate was prepared as follows: 10 g of 2,3,4-trihydroxybenzoic

Results

no Human papillomavirus HPV 6/18 virus remained 24 hours after treatment with 50 µl micro emulsion containing 10 % off title compound

Citation

QIN, Weihua

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

human

Assay Description

Effect : condyloma acuminata; effect on Example 5 Clinical Use of Hydroxybenzoic Acid Ester in Treating Condyloma Acuminata Diagnosis Standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of Health

Results

treatment with title compound had more apparent treatment effect compared with recombinant human interferon α-2β gel; treatment with title compound showed that in 4 patients more than 70% of skin lesions disappeared after 1-8 days, 4 patients

Citation

QIN, Weihua

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : HBeAg secretion; inhibition of Bioassay : hepatitis B 2.2.15 cells Example 6 Inhibition Effect of Hydroxybenzoic Acid Ester Analogue on Secretion of HBsAg and HBeAg by Hepatitis B 2.2.15 Cell Line Experiment Materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological

Results

treatment with 2 µmol/ml title compound gave an inhibition rate of 9.4%

Citation

QIN, Weihua

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : HBsAg secretion; inhibition of Bioassay : hepatitis B 2.2.15 cells Example 6 Inhibition Effect of Hydroxybenzoic Acid Ester Analogue on Secretion of HBsAg and HBeAg by Hepatitis B 2.2.15 Cell Line Experiment Materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological

Results

treatment with 2 µmol/ml title compound gave an inhibition rate of 8.3%

Citation

QIN, Weihua

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antibiofilm

Biological material

Staphylococcus aureus

Assay Description

Effect : biofilm formation; inhibition of

Results

MBIC90 > 2010 μmol/l

Citation

BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS

Patent: US2012/88671 A1, 2012 ; Title/Abstract Full Text Show Details

Target

Adiponectin:Wild

Assay Description

Effect : adiponectin expression; effect on Bioassay : Example 1: Enhancement of adiponectin expression by (-)-catechin in adipocytesStep 1) Adipocyte DifferentiationMouse 3T3-L1 (ATCC No. CL 173) preadipocyte cells were incubated in DMEM


(Dulbecco's modified Eagle's Medium, Gibco 1210-0038) containing 10% calf serum in 10% CO2 incubator, while

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Citation

LEE, Tae Ryong; BAIK, Joo-Hyun; LEE, Byeong Gon; LEE, Hyoung Ho; CHO, Si Young; SHIN, Dong Wook; KIM, Young-Kyung; PARK, Pil Joon; SHIN, Hyun Jung; SHIN, Euiseok

Patent: WO2007/126293 A1, 2007 ; Title/Abstract Full Text Show Details

Effect

Immunosuppressant

Assay Description

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Results

blocked the granule exocytosis in a dose-dependent manner

Citation

Hamada, Shin-Ichi; Kataoka, Takao; Woo, Je-Tae; Yamada, Atsushi; Yoshida, Takashi; Nishimura, Toshio; Otake, Noboru; Nagai, Kazuo

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 9 p. 1017 - 1019 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

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not affects cell viability

Citation

Hamada, Shin-Ichi; Kataoka, Takao; Woo, Je-Tae; Yamada, Atsushi; Yoshida, Takashi; Nishimura, Toshio; Otake, Noboru; Nagai, Kazuo

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 9 p. 1017 - 1019 Title/Abstract Full Text View citing articles Show Details

Effect

Antifungal

Biological material

Cryptococcus neoformans

Bioassay : adaptation of an antifungal bioassay recommended by the National Committee on Clinical Laboratory Standards

Citation

Li; ElSohly; Nimrod; Clark

Planta Medica, 1999 , vol. 65, # 8 p. 780 - 780 Title/Abstract Full Text View citing articles Show Details

Effect

Antiallergic

Biological material

Caco-2

Assay Description

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Target : OE4 cells Bioassay : in vitro; MTT: 3-(4,5-dimethylthiazol-2-yl)2,5-diphenyl tetrazolium bromide assay

Results

Assay Description

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Target : OE4 cells Bioassay : in vitro; granule exocytosis assay; cells preincubated with drug for 2 h; stimulated with immobilized anti-CD3; granzyme A activity in the culture supernatant measured

Bioassay : measurement of inhibitory activity against fluorescein isothiocyanate-labeled ovalbumin permeation through test system monolayers; incubation at 37 deg C for 30 min; fluorescence intensity determination

Results

title comp. showed inhibitory activity at concentration of 10-6 mol/l; graphical representation

Citation

Kobayashi, Shoko; Watanabe, Jun; Fukushi, Eri; Kawabata, Jun; Nakajima, Mitsutoshi; Watanabe, Michiko

Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 6 p. 1250 - 1257 Title/Abstract Full Text View citing articles Show Details

Target

Sulfotransferase 1A1:Wild

Biological material

human thrombocyte

Assay Description

Effect : |enzyme; inhib. of


Bioassay : incubated for 20 min; liquid scintillation counting effect on enzyme activity specific for sulfation of monoamines evaluated; dopamine used as substrate; 6.7 μmol/l <35S>-3'-phosphoadenosine5'-phosphosulfate (spec. act.: 1.0-1.5 Ci/mmol); potassium phosphate buffer, pH 7.0; 37 deg C

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Results

title comp. inhibited enzyme activity by -3.9 percent

Citation

Yeh, Chi-Tai; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2003 , vol. 51, # 5 p. 1474 - 1479 Title/Abstract Full Text View citing articles Show Details

Target

Sulfotransferase 1A1:Wild

Biological material

human thrombocyte

Assay Description

Effect : |enzyme; inhib. of Bioassay : incubated for 20 min; liquid scintillation counting effect on enzyme activity specific for sulfation of small phenols evaluated; p-nitrophenol used as substrate; 6.7 μmol/l <35S>-3'phosphoadenosine-5'-phosphosulfate (spec. act.: 1.0-1.5 Ci/mmol); potassium phosphate buffer, pH 7.0; 37 deg C

Results

title comp. inhibited enzyme activity by -14.0 percent

Citation

Yeh, Chi-Tai; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2003 , vol. 51, # 5 p. 1474 - 1479 Title/Abstract Full Text View citing articles Show Details

Results

weak inhibition of the pollen germination of Camellia japonica at 1000 ppm

Citation

Kobayashi, Satoshi; Ariga, Masato; Ozawa, Tetsuo; Imagawa, Hiroshi

Agricultural and Biological Chemistry, 1984 , vol. 48, # 2 p. 389 - 396 Title/Abstract Full Text Show Details

Assay Description

Effect : |drug interaction Target : rat epididymal adipocytes Bioassay : ratio of 1 indicates no increase in activity effect on isulin activity evaluated; glucose spiked with <U-14C>glucose; Krebs-Ringer phosphate buffer, pH 7.4; room temp.; incubated for 1 h; quantitation of 14CO2 release; insulin enhancing ratio determined

Results

title comp. exhibited insulin enhancing ratio of 1.7

Citation

Anderson, Richard A.; Polansky, Marilyn M.

Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 24 p. 7182 - 7186 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

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Target : CD-1 (ICR) mouse peritoneal macrophages Bioassay : control: untreated cells; TBARS: thiobarbituric acid reactive substances; TBARS value of control was taken as 100 percent cells were preincubated with title comp. for 4 h in Ham's F-10 medium; washed with PBS; low density lipoprotein added; incubated for 20 h; absorbance measured at 535 nm in UV spectrophotometer; malondialdehyde generated measured by TBARS formation

Results

title comp. pretreatment inhibited macrophage-mediated low density lipoprotein oxidation with TBARS value of 99.3 and 74.7 percent of control at 100 and 400 μmol/l, respectively; table

Citation

Yoshida, Hiroshi; Ishikawa, Toshitsugu; Hosoai, Hiroshi; Suzukawa, Michio; Ayaori, Makoto; Hisada, Tetsuya; Sawada, Shojiro; Yonemura, Atsushi; Higashi, Kenji; Ito, Toshimitsu; Nakajima, Kei; Yamashita, Takeshi; Tomiyasu, Koji; Nishiwaki, Masato; Ohsuzu, Fumitaka; Nakamura, Haruo

Biochemical Pharmacology, 1999 , vol. 58, # 11 p. 1695 - 1703 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

Results

Target : CD-1 (ICR) mouse peritoneal macrophages Bioassay : control: untreated cells cells were preincubated with title comp. for 4 h at 37 deg C in Ham's F-10 medium; lactate dehydrogenase activity measured; washed; incubated with <3H>thymidine for 6 h; <3H>thymidine incorporation into DNA measured; cell viability determined title comp. had no major effect on cell viability; table


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Citation

Yoshida, Hiroshi; Ishikawa, Toshitsugu; Hosoai, Hiroshi; Suzukawa, Michio; Ayaori, Makoto; Hisada, Tetsuya; Sawada, Shojiro; Yonemura, Atsushi; Higashi, Kenji; Ito, Toshimitsu; Nakajima, Kei; Yamashita, Takeshi; Tomiyasu, Koji; Nishiwaki, Masato; Ohsuzu, Fumitaka; Nakamura, Haruo

Biochemical Pharmacology, 1999 , vol. 58, # 11 p. 1695 - 1703 Title/Abstract Full Text View citing articles Show Details

Effect

Cytoprotective

Biological material

Rattus norvegicus liver cell

Assay Description

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Results

title comp.-Fe(3+) complex was much more effective than uncomplexed title comp. at preventing reactive oxygen species-mediated hypoxia-reoxygenation injury in hepatocytes; table

Citation

Moridani, Majid Y.; O'Brien, Peter J.

Biochemical Pharmacology, 2001 , vol. 62, # 12 p. 1579 - 1585 Title/Abstract Full Text View citing articles Show Details

Effect

Oxidant

Assay Description

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title comp. induced peroxide production; effect was slightly inhibited by BAPTA-AM

Citation

Inoue; Sakaguchi; Isuzugawa; Tani; Ogihara

Biological and Pharmaceutical Bulletin, 2000 , vol. 23, # 10 p. 1153 - 1157 Title/Abstract Full Text View citing articles Show Details

Effect

Oxidant

Target : human promyelocytic leukemia HL-60RG cells Bioassay : DCFH-DA: 5,6-carboxy-2',7'-dichlorofluorescin diacetate; further investigations with antioxidant and radical scavengers; NAC: N-acetyl-L-cysteine, antioxidant; SOD: superoxide dismutase; reference comp.: 50 μmol/l H2O2 cells were preloaded with DCFH-DA for 30 min prior to addition of title comp.; intracellular peroxide detected at 0, 5, 10, 20 min after title comp. addition by measuring fluorescence due to oxidation of DCFH-DA

Results

title comp. induced time-dependent peroxide production; effect was suppressed by NAC, ascorbic acid, SOD/catalase and slightly by catalase; H2O2-induced peroxide generation suppressed by SOD/catalase and catalase and not by NAC and ascorbate

Citation

Inoue; Sakaguchi; Isuzugawa; Tani; Ogihara

Biological and Pharmaceutical Bulletin, 2000 , vol. 23, # 10 p. 1153 - 1157 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Assay Description

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Target : human promyelocytic leukemia HL-60RG cells Bioassay : DCFH-DA: 5,6-carboxy-2',7'-dichlorofluorescin diacetate; BAPTA-AM: intracellular Ca(2+) chelator cells were preloaded with DCFH-DA in combination with BAPTA-AM for 30 min prior to title comp. addition; intracellular peroxide level detected at 5 min after title comp. addition by measuring fluorescence due to DCFH-DA oxidation

Results

Assay Description

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Bioassay : hepatocytes incubated with title comp. or its Fe(3+) complex under an atmosphere of 95 percent N2 and 5 percent CO2 for 90 min; before re-oxygenation with 1 percent O2, 94 percent N2 and 5 percent CO2, viability of cells determined by trypan blue exclusion

Target : Salmonella typhimurium TA102 Bioassay : bacterial culture in agar was incubated with title comp. alone or in presence of bleomycin; toxic effect of title comp. to test system assessed

Citation

Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Assay Description

Target : Salmonella typhimurium TA102 Bioassay : bacterial culture in agar was incubated with title comp. alone or in presence of H2O2; toxic effect of title comp. to test system assessed


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Citation

Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

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Citation

Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

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Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details

Effect

Mutagenic

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Target : Salmonella typhimurium TA102 Bioassay : bacterial culture in agar incubated with title comp. for 48 h at 37 deg C; number of histidine revertant colonies counted microscopically; mutagenic effect of title comp. determined

Citation

Stagos, Demetrios; Kazantzoglou, Georgios; Theofanidou, Demetra; Kakalopoulou, Georgia; Magiatis, Prokopios; Mitaku, Sofia; Kouretas, Demetrios

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 609, # 2 p. 165 - 175 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

107 of 515

Target : Salmonella typhimurium TA102 Bioassay : positive control: without title comp. bacterial culture in agar incubated with title comp. in presence of H2O2 for 48 h at 37 deg C; number of histidine revertant colonies counted microscopically; inhibition of bleomycin- and H2O2-induced mutagenicity determined

Citation

Assay Description

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Target : Salmonella typhimurium TA102 Bioassay : positive control: without title comp. bacterial culture in agar incubated with title comp. in presence of bleomycin for 48 h at 37 deg C; number of histidine revertant colonies counted microscopically; inhibition of bleomycin- and H2O2-induced mutagenicity determined

Target : microglial BV2 cells of mouse Bioassay : cells in DMEM were treated with title comp. for 1 h and then stimulated with 1 ng/ml lipopolysaccharide (LPS); after 24 h of incubation cell viability assayed by 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide (MTT) assay

Citation

Mi, Kyeong Lee; Hee, Young Jeon; Ki, Yong Lee; Seung, Hyun Kim; Choong, Je Ma; Sang, Hyun Sung; Lee, Heum-Sook; Mi, Jung Park; Young, Choong Kim

Planta Medica, 2007 , vol. 73, # 8 p. 782 - 786 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : mutation rate; effect on Target : Salmonella typhimurium TA102 Bioassay : control: vehicle; reference comp.: benzidine and hydrogen peroxide reaction mixture included 100 μl of overnight bacterial culture, 100 μl of title comp. solution, and no or 500 μl of rat liver S9 mix; after incubation mixture was plated in minimal agar; 48 h later revertant colonies were counted

Citation

Makena, Patrudu S.; Chung, King-Thom

Food and Chemical Toxicology, 2007 , vol. 45, # 10 p. 1899 - 1909 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Target : Salmonella typhimurium TA102 Bioassay : controls: dimethyl sulfoxide (DMSO) alone or benzidine alone 100 μl of benzidine was added to 100 μl of overnight bacterial culture in presence or absence of 500 μl of rat liver S9 mix; incubation with 100 μl title comp.; plating in minimal agar; 48 h later revertant colonies were counted


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Results

50, 100, and 200 μg/plate title comp. reduced number of revertants/plate in presence of S9 from 1049 in benzidine control to 483, 393, and 287, resp., compared to 325 in DMSO control; title comp. also reduced number of revertants in absence of S9;

Citation

Makena, Patrudu S.; Chung, King-Thom

Food and Chemical Toxicology, 2007 , vol. 45, # 10 p. 1899 - 1909 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

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Target : Salmonella typhimurium TA102 Bioassay : control: vehicle; reference comp.: benzidine and hydrogen peroxide reaction mixture consisted of 100 μl overnight bacterial culture, 100 μl of title comp. solution, and no or 500 μl of rat liver S9 mix; incubation for 4 h; then trypan blue dye was added and viable or dead cell were counted using hemocytometer

Citation

Makena, Patrudu S.; Chung, King-Thom

Food and Chemical Toxicology, 2007 , vol. 45, # 10 p. 1899 - 1909 Title/Abstract Full Text View citing articles Show Details

Biological material

RAW 264.7 cell line

Assay Description

Effect : NO production; inhibition of Bioassay : inhibition ( percent): (1-((title comp. data) - (negative control data))/((positive control data) - (negative control data)*100 percent; LPS: lipopolysaccharide: IFN-γ: interferon-γ LPS/IFN-γstimulated test cells incubated with title comp.; level of extracelluar NO measured using Griess mod

Citation

Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details

Biological material

RAW 264.7 cell line

Assay Description

Effect : peroxide anion production; inhibition of Bioassay : inhibition ( percent): (1-((title comp. data) - (negative control data))/((positive control data) - (negative control data)*100 percent; LPS: lipopolysaccharide: IFN-γ: interferon-γ LPS/IFN-γstimulated test cells incubated with title comp.; level of extracelluar O2(1-) measured using cytochrome c reduction method

Results

inhibition 30.9 percent

Citation

Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details

Biological material

RAW 264.7 cell line

Assay Description

Effect : peroxinitrite anion production; inhibition of Bioassay : inhibition ( percent): (1-((title comp. data) - (negative control data))/((positive control data) - (negative control data)*100 percent; LPS: lipopolysaccharide: IFN-γ: interferon-γ LPS/IFN-γstimulated test cells incubated with title comp.; level of extracelluar ONOO(1-) measured using dehydrorhodamine 123 method

Results

inhibition 9.3 percent

Citation

Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details

Biological material

RAW 264.7 cell line

Assay Description

Effect : RONS production; inhibition of Bioassay : RONS: reactive oxygen and nitrogen species; AS52 cells: Chinese hamster ovary AS52 cells; LPS: lipopolysaccharide: IFN-γ: interferon-γ 5E5 test cells co-cultured with AS52 cells at ratio 1:1, incubated with 100 ng/ml LPS, 100 U/ml IFN-γ and title comp. for 24 h; test cell generated RONS induced mutation inhibition in AS52 cells investigated

Results

mutation inhibition 54.7 percent

Citation

Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime


Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details

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Effect

Cytotoxic

Biological material

RAW 264.7 cell line

Assay Description

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Results

cell viability 87.5 percent

Citation

Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human HL-60 cell line

Assay Description

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Bioassay : LPS: lipopolysaccharide: IFN-γ: interferon-γ LPS/IFN-γ-stimulated test cells incubated with title comp.; cell viability investigated

Bioassay : 1E6 cells incubated with title comp. at 37 deg C for 15 min, incubated with 100 nmol/l 12-O-tetradecanoylphorbol-13-acetate for 15 min

Results

cell viability 79.3 percent

Citation

Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details

Biological material

human HL-60 cell line

Assay Description

Effect : peroxide anion production; inhibition of Bioassay : inhibition ( percent): (1-((title comp. data) - (negative control data))/((positive control data) - (negative control data)*100 percent 1E6 cells incubated with title comp. at 37 deg C for 15 min, incubated with 100 nmol/l 12-O-tetradecanoylphorbol-13-acetate for 15 min; level of extracelluar O2(1-) measured using cytochrome c reduction method

Results

inhibition 27.2 percent

Citation

Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details

Biological material

human HL-60 cell line

Assay Description

Effect : RONS production; inhibition of Bioassay : RONS: reactive oxygen and nitrogen species; AS52 cells: Chinese hamster ovary AS52 cells 5E5 test cells co-cultured with AS52 cells at ratio 1:1, incubated with title comp. and 100 nmol/l 12O-tetradecanoylphorbol-13-acetate for 1 h; test cell generated RONS induced mutation inhibition in AS52 cells investigated

Results

mutation inhibition 35.4 percent

Citation

Kim, Ha Won; Murakami, Akira; Williams, Marshall V.; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 238 - 242 Title/Abstract Full Text View citing articles Show Details

Target

Transcription factor AP-1:Wild

Biological material

human HT-29

Assay Description

Effect : AP-1 transcriptional activity; effect on Bioassay : EGCG: (-)-epigallocatecin-3-gallate; AP-1: activator protein-1; dietary antioxidants AP-1 promoter/luciferase and control vectors transfected into cells; pretreated with title comp. for 30 min; exposed to EGCG or vehicle for 1 h; washed; incubated with title comp. for 17 h; harvested; AP-1 activity assayed


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Results

inhibited EGCG-upregulated AP-1 transcription activity by 77% (diagram)

Citation

Kim, Mihye; Murakami, Akira; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 10 p. 2442 - 2450 Title/Abstract Full Text View citing articles Show Details

Biological material

human HT-29

Assay Description

Effect : mRNA expression; effect on Bioassay : EGCG: (-)-epigallocatecin-3-gallate; MMP-7: matrix metalloprotease-7; GAPDH: glyceraldehyde-3-phosphate-dehydrogenase; vehicle-treated (6 h) cells expressed MMP7 mRNA at low level; EGCG upregulated MMP7 expression by 2.7 fold cells pretreated with vehicle or title comp. for 30 min; exposed to EGCG or vehicle for 1 h; washed; incubated in serum-free DMEM for 5 h; harvested; total RNA extracted; reverse transcriptase-polymerase chain reaction; GAPDH as internal control

Results

no effect on MMP-7 mRNA expression compared with vehicle; signif. suppressed EGCG-upregulated MMP-7 mRNA expression (diagram)

Citation

Kim, Mihye; Murakami, Akira; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 10 p. 2442 - 2450 Title/Abstract Full Text View citing articles Show Details

Biological material

human HT-29

Assay Description

Effect : pro-matrix metalloproteinase production; effect on Bioassay : EGCG: (-)-epigallocatecin-3-gallate; proMMP-7: pro-matrix metalloprotease-7; dietary antioxidants; 25 μM of EGCG enhanced production of intracellular proMMP-7 protein by 6-fold cells pretreated with title comp. or DMSO for 30 min; exposed to EGCG or vehicle for 1 h; cells washed with PBS; incubated in serum-free DMEM for 23 h; Western blotting; DMSO as negative control

Results

reduced EGGG-enhanced proMMP-7 production; no effect on spontaneous proMMP-7 production (diagram); similar effect for extracellular proMMP-7 protein

Citation

Kim, Mihye; Murakami, Akira; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 10 p. 2442 - 2450 Title/Abstract Full Text View citing articles Show Details

Biological material

human HT-29

Assay Description

Effect : H2O2 production; effect on Bioassay : EGCG: (-)-epigallocatecin-3-gallate; dietary antioxidants; spontaneous and EGCG-induced H2O2 generation cells pretreated with title comp. for 30 min; exposed to EGCG or vehicle for 30 min; harvested; H2O2 conc. determined by ferrous ion-oxidation-xylenol orange method; visible absorption at 550 nm measured

Citation

Kim, Mihye; Murakami, Akira; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 10 p. 2442 - 2450 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic

Assay Description

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Bioassay : positive control: maleic hydrazide; negative control: aerated Hoagland's solution secondary roots of test system exposed to title comp. for 6 h; after 24 h of recovery, root tips were fixed overnight in Carnoy's solution at 4 deg C; hydrolyzed; slides prepared; stained; frequencies of micronucleus scored; mitotic index calculated

Results

title comp. treatment resulted in mitotic index ranging between 2 and 17%; title comp. induced a strong increase in micronucleus frequency, 7.5-fold above negative control and not significantly different from positive control; fig.

Citation

El Hajjouji; Pinelli; Guiresse; Merlina; Revel; Hafidi

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2007 , vol. 634, # 1-2 p. 25 - 31 Title/Abstract Full Text View citing articles Show Details

Effect

Antiviral

Biological material

Chlorocebus aethiops VERO

Assay Description

Effect : plaque formation Target : HSV-1 cell monolayer tested; HSV: herpes simplex virus


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Citation

Tian, Li-Wen; Zhang, Ying-Jun; Qu, Chang; Wang, Yi-Fei; Yang, Chong-Ren

Journal of Natural Products, 2010 , vol. 73, # 2 p. 160 - 163 Title/Abstract Full Text View citing articles Show Details

Biological material

Caenorhabditis elegans

Assay Description

Effect : lifespan Bioassay : L4 larva no significant lifespan change at 300 μmol/l was foundin presence of dead bacteria;

Results

mean lifespan change rate 105 - 111.73 percent

Citation

Saul, Nadine; Pietsch, Kerstin; Stuerzenbaum, Stephen R.; Menzel, Ralph; Steinberg, Christian E. W.

Journal of Natural Products, 2011 , vol. 74, # 8 p. 1713 - 1720 Title/Abstract Full Text View citing articles Show Details

Biological material

Caenorhabditis elegans

Assay Description

Effect : lifespan Species : Caenorhabditis elegans eat-2(ad465) Bioassay : L4 larva

Citation

Saul, Nadine; Pietsch, Kerstin; Stuerzenbaum, Stephen R.; Menzel, Ralph; Steinberg, Christian E. W.

Journal of Natural Products, 2011 , vol. 74, # 8 p. 1713 - 1720 Title/Abstract Full Text View citing articles Show Details

Biological material

Caenorhabditis elegans

Assay Description

Effect : lifespan Species : Caenorhabditis elegans mev-1(kn-1) Bioassay : L4 larva

Results

mean lifespan change rate 106.76 percent

Citation

Saul, Nadine; Pietsch, Kerstin; Stuerzenbaum, Stephen R.; Menzel, Ralph; Steinberg, Christian E. W.

Journal of Natural Products, 2011 , vol. 74, # 8 p. 1713 - 1720 Title/Abstract Full Text View citing articles Show Details

Target

Aldose reductase:Wild + Aldose reductase [human]:Wild

Biological material

human

Assay Description

Effect : enzyme activity diabetes complications Bioassay : recombinant aldose reductase spectrophotometric assay

Citation

Lee, Yeon Sil; Kim, Jin Kyu; Bae, Young Soo; Won, Moo-Ho; Kang, Il-Jun; Lim, Soon Sung

Archives of Pharmacal Research, 2011 , vol. 34, # 2 p. 211 - 215 Title/Abstract Full Text View citing articles Show Details

Target

Aminopeptidase N:Wild

Assay Description

Effect : enzyme activity Bioassay : aminopeptidase N

Citation

Kiss, Anna K.; Derwinska, Malgorzata; Dawidowska, Anna; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 17 p. 7845 - 7852 Title/Abstract Full Text View citing articles Show Details


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Effect

Antiinflammatory

Biological material

human neutrophil

Assay Description

Effect : LPS-stimulated IL-8 release LPS: lipopolysacharide; IL-8: interleukin-8; ELISA

Citation

Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details

Effect

Antiinflammatory

Biological material

human neutrophil

Assay Description

Effect : f-MLP and cytochalasin B-stimulated LTB4 release f-MLP: formyl-Met-Leu-phenylalanine; LTB4: leukotriene B4; ELISA

Citation

Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details

Effect

Antiinflammatory

Biological material

human neutrophil

Assay Description

Effect : f-MLP-stimulated elastase release f-MLP: formyl-Met-Leu-phenylalanine; spectrophotometric assay

Citation

Kiss, Anna K.; Filipek, Agnieszka; Czerwinska, Monika; Naruszewicz, Marek

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 18 p. 9960 - 9966 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Biological material

Salmonella enterica serovar Typhimurium

Assay Description

Effect : his+ revertants/plate Bioassay : incubation at 37 deg C; title comp. and mutagen were dissolved in DMSO; NPD as positive control (considered as 100 percent mutagenicity); his+ revertants counted Ames assay (plate incorporation test); co-incubation and pre-incubation procedures; effect of title comp. against 2-aminofluorene (2-AF)-induced mutagenicity

Results

moderate dose-dependent inhibitory effect, being not more than 50 percent, more expressed at pre-incubation assay

Citation

Kaur, Simran; Grover; Singh, Majar; Kaur, Satwinderjeet

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 1998 , vol. 419, # 1-3 p. 169 - 179 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Biological material

Salmonella enterica serovar Typhimurium

Assay Description

Effect : his+ revertants/plate Bioassay : incubation at 37 deg C; title comp. and mutagen were dissolved in DMSO; NPD as positive control (considered as 100 percent mutagenicity); his+ revertants counted Ames assay (plate incorporation test); co-incubation and pre-incubation procedures; effect of title comp. against 4-nitro-o-phenylenediamine (NPD)-induced mutagenicity

Results

unsignificant dose-dependent inhibitory effect, more expressed at co-incubation assay

Citation

Kaur, Simran; Grover; Singh, Majar; Kaur, Satwinderjeet

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 1998 , vol. 419, # 1-3 p. 169 - 179 Title/Abstract Full Text View citing articles Show Details


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Effect

Antimutagenic

Biological material

Salmonella enterica serovar Typhimurium

Assay Description

Effect : his+ revertants/plate Bioassay : incubation at 37 deg C; 4-NQNO as positive control (considered as 100 percent mutagenicity); his+ revertants counted Ames assay (plate incorporation test); effect of title comp. against 4nitroquinoline-N-oxide (4-NQNO)-induced mutagenicity

Citation

Kaur, Simran; Grover; Singh, Majar; Kaur, Satwinderjeet

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 1998 , vol. 419, # 1-3 p. 169 - 179 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

Effect : acute cells death Target : Fischer-344 rats Bioassay : rats 260-290 g mass; incubation in Krebs-Henseleit buffer; 37 deg C; pH 7.4; vehicle, DMSO; hepatocytes 1E6 cells/ml; incubation time, 30, 60 and 90 min liver hepatocytes isolated; biochemical assay; conc. protein determination; HPLC technique

Results

caused cell death 25 percent (control 23 percent) after 3 h; concentration-dependent cell death, losses of cellular GSH and protein thiol levels; appearance of cell blebbing; abrupt depletion of ATP and adenine nucleotides pool

Citation

Nakagawa; Tayama

Archives of Toxicology, 1995 , vol. 69, # 3 p. 204 - 208 Title/Abstract Full Text Show Details

Effect

Cytotoxic

Assay Description

Effect : mitochondria dysfunction Target : Fischer-344 rats Bioassay : mitochondria 1 mg protein/ml; respiration buffer; 25 deg C; pH 7.4; in presence and exhaustion of ADP, 20 μM mitochondria isolated; rate oxygen consumption measurement

Results

concentration-dependent increase in rate of state 4 oxygen consumption; uncoupling effect of oxidative phosphorylation in mitochondria; respiratory control index 4.4-3.8 (control 4.4)

Citation

Nakagawa; Tayama

Archives of Toxicology, 1995 , vol. 69, # 3 p. 204 - 208 Title/Abstract Full Text Show Details

Effect

Phytotoxic

Assay Description

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Target : Zea mays L., maize inbred Mp313E x SC212M hybrid Bioassay : milk-stage kernels; water solution; 18 kernels punctured through the pericarp in vitro

Results

browning of pericarp after 4 and 24-hr (mm): 1.2+/-0.7, 1.8+/-0.9; controls: 0.1+/-0.3 and 0.7+/-0.3, respectively

Citation

Dowd, Patrick

Journal of Chemical Ecology, 1994 , vol. 20, # 11 p. 2777 - 2804 Title/Abstract Full Text View citing articles Show Details

Effect

Phytotoxic

Assay Description

Target : Zea mays L., maize inbred Mp313E Bioassay : milk-stage kernels; water solution; 18 kernels punctured through the pericarp in vitro

Results

browning of pericarp after 4 and 24-hr (mm): 1.5+/-0.7, 2.9+/-0.7; controls: 0.5+/-0.2 and 1.2+/-0.5, respectively

Citation

Dowd, Patrick

Journal of Chemical Ecology, 1994 , vol. 20, # 11 p. 2777 - 2804 Title/Abstract Full Text View citing articles Show Details


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Effect Assay Description

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Phytotoxic

Target : Zea mays L., maize inbred SC212M Bioassay : milk-stage kernels; water solution; 18 kernels punctured through the pericarp in vitro

Results

browning of pericarp after 4 and 24-hr (mm): 0.2+/-0.3, 0.6+/-0.2; controls: 0.0+/-0.0 and 0.4+/-0.2, respectively

Citation

Dowd, Patrick

Journal of Chemical Ecology, 1994 , vol. 20, # 11 p. 2777 - 2804 Title/Abstract Full Text View citing articles Show Details

Results

antioxidative activity in β-carotene aqueous model system, at 50E-5percent 1.06; at 1E-5M 1.05 relative antioxidative activity

Citation

Ariga, Toshiaki; Koshiyama, Ikunori; Fukushima, Danji

Agricultural and Biological Chemistry, 1988 , vol. 52, # 11 p. 2717 - 2722 Title/Abstract Full Text Show Details

Results

no coenzymatic activity for vitamin B2-aldehyde forming enzyme

Citation

Oka, Masanori; Tachibana, Sei

Agricultural and Biological Chemistry, 1984 , vol. 48, # 11 p. 2893 - 2896 Title/Abstract Full Text Show Details

Results

inhibition effect of rat small intestinal sucrase and α-glucosidase activities

Citation

Honda, Miwa; Hara, Yukihiko

Bioscience, Biotechnology, and Biochemistry, 1993 , vol. 57, # 1 p. 123 - 124 Title/Abstract Full Text Show Details

Results

no inhibitory effect on crude rat lens aldose reductase

Citation

Shimizu; Horie; Terashima; Ueno; Hayashi; Arisawa; Suzuki; Yoshizaki; Morita

Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2531 - 2532 Title/Abstract Full Text View citing articles Show Details

Results

growth inhibition of mutants 3937 cbs29, 3937 fct18 and 3937 fct34 acsA12 of bacterium Erwinia chrysanthemi

Citation

Mila, Isabelle; Scalbert, Augustin; Expert, Dominique

Phytochemistry, 1996 , vol. 42, # 6 p. 1551 - 1555 Title/Abstract Full Text View citing articles Show Details

Results

radical scavenging activity; antioxidative activity in the rabbit erythrocyte membrane ghost system; suppressive effect on pentosidine formation

Citation

Oya; Osawa; Kawakishi

Bioscience, Biotechnology and Biochemistry, 1997 , vol. 61, # 2 p. 263 - 266 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

Target : cells of digestive gland of Unio tumidus, fresh-water mussel Bioassay : control: no treatment cells treated with title comp. for 1 h at 5 deg C; trypan-blue dye exclusion assay performed

Results

title comp. dose-dependently reduced viability; fig.

Citation

Labieniec, Magdalena; Gabryelak, Teresa

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 603, # 1 p. 48 - 55


Title/Abstract Full Text View citing articles Show Details

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Effect Assay Description

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title comp. induced DNA damage, effect enhanced after FPG or proteinase K treatment; fig.

Citation

Labieniec, Magdalena; Gabryelak, Teresa

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 603, # 1 p. 48 - 55 Title/Abstract Full Text View citing articles Show Details

Effect

Oxidant

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Target : cells of digestive gland of Unio tumidus, fresh-water mussel Bioassay : control: no treatment cells treated with title comp. for 1 h at 5 deg C; Ellman's reagent added, thiol groups det. spectrophotometrically at 412 nm

Results

15-60 μM title comp. dose-dependently reduced thiol group content; fig.

Citation

Labieniec, Magdalena; Gabryelak, Teresa

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 603, # 1 p. 48 - 55 Title/Abstract Full Text View citing articles Show Details

Effect

Toxic

Biological material

HL-60 cell line

Assay Description

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Target : cells of digestive gland of Unio tumidus, fresh-water mussel Bioassay : control: no treatment (buffer) cells treated with title comp. for 30 min at 37 deg C followed by FPG post-treatment or proteinase K (2 h) treatment; comet assay at pH 13

Results

Assay Description

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Genotoxic

Bioassay : cells incubated with title comp. for 48 h; XTT-PMS solution added to each well; after incubating for 4 h at 37 deg C absorbance measured

Citation

Agnihotri, Vijai K.; ElSohly, Hala N.; Khan, Shabana I.; Smillie, Troy J.; Khan, Ikhlas A.; Walker, Larry A.

Phytochemistry, 2008 , vol. 69, # 10 p. 2061 - 2066 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : hydrogen peroxide production; effect on Target : colon adenoma LT97 cells of human Bioassay : control: without title comp.; further study: addition of catalase on title comp. effect cells incubated with title comp. at 37 deg C for 10 to 180 min; FOX2 reagent added; incubated at 30 min at room temperature; centrifuged; supernatant collected; absorbance measured at 550 nm

Results

title comp. was less effective, signif. hydrogen peroxide production were detected for 88 μM after 10 min of incubation; addition of catalase reduced signal to zero which indicates which indicates title comp. treatment in H202 formation; fig.

Citation

Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : hydrogen peroxide production; effect on Target : colon adenoma LT97 cells of human Bioassay : control: without title comp. cells incubated with title comp. at 37 deg C up to 1 h; FOX2 reagent added; incubated at 30 min at room temperature; centrifuged; supernatant collected; absorbance measured at 550 nm;

Citation

Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |metabolic Target : colon adenoma LT97 cells of human Bioassay : control: untreated cells cells incubated with title comp. for 24 to 72 h; CellTitre-Blue TM added 2 h before the end of incubation period; fluorescence activity measured (excitation at 520


nm/emission at 595 nm); metabolic activity detd.

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Citation

Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Biological material

HT-29

Assay Description

Effect : hydrogen peroxide production; effect on Bioassay : control: without title comp.; further study: addition of catalase on title comp. effect cells incubated with title comp. at 37 deg C for 10 to 180 min; FOX2 reagent added; incubated at 30 min at room temperature; centrifuged; supernatant collected; absorbance measured at 550 nm

Results

title comp. was less effective, signif. hydrogen peroxide production were detected for 88 μM after 10 min of incubation; addition of catalase reduced signal to zero which indicates which indicates title comp. treatment in H202 formation; fig.

Citation

Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Biological material

HT-29

Assay Description

Effect : hydrogen peroxide production; effect on Bioassay : control: without title comp. cells incubated with title comp. at 37 deg C for up to 1 h; FOX2 reagent added; incubated at 30 min at room temperature; centrifuged; supernatant collected; absorbance measured at 550 nm

Citation

Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Biological material

HT-29

Assay Description

Effect : |metabolic Bioassay : control: untreated cells cells incubated with title comp. for 12 to 72 h; CellTitre-Blue TM added 2 h before the end of incubation period; fluorescence activity measured (excitation at 520 nm/emission at 595 nm); metabolic activity detd.

Citation

Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Effect

Antiproliferative

Assay Description

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Target : colon adenoma LT97 cells of human Bioassay : control: without title comp. cells incubated with title comp. for 12 to 72 h; 2 h before the end of post treatment, 10 μl5-bromo-2-deoxyuridine added; DNA-synthesis detd. using chemiluminescence

Citation

Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Effect

Antiproliferative

Biological material

HT-29

Assay Description

Citation

Bioassay : control: without title comp. cells incubated with title comp. for 12 to 72 h; 2 h before the end of post treatment, 10 μl5-bromo-2-deoxyuridine added; DNA-synthesis detd. using chemiluminescence Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details


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Effect Assay Description

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Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

HT-29

Bioassay : control: without title comp. cells incubated with title comp. for 12 to 72 h; amount of DNA which is related to the number of cells detd.

Citation

Klenow; Glei; Haber; Owen; Pool-Zobel

Food and Chemical Toxicology, 2008 , vol. 46, # 4 p. 1389 - 1397 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : immobilized enzyme assay system; incubation with 18 mM/l maltose and title comp. for 30 min at 37 deg C; maltase activity determined by measuring glucose liberated from maltose by Glucose F-kit; data are presented as Inhibitory ratio under fixed conc.

Results

Inhibitory ratio:71.0 percent

Citation

Matsui, Toshiro; Ebuchi, Sumi; Fukui, Keiichi; Matsugano, Kazusato; Terahara, Norihiko; Matsumoto, Kiyoshi

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 11 p. 2239 - 2246 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : immobilized enzyme assay system; incubation with 8 mM/l sucrose and title comp. for 30 min at 37 deg C; sucrase activity determined by measuring glucose liberated from maltose by Glucose F-kit; data are presented as Inhibitory ratio under fixed conc.

Results

Inhibitory ratio:9.7 percent

Citation

Matsui, Toshiro; Ebuchi, Sumi; Fukui, Keiichi; Matsugano, Kazusato; Terahara, Norihiko; Matsumoto, Kiyoshi

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 11 p. 2239 - 2246 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

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Target : colon adenoma LT97 cells of human Bioassay : control: without title comp. cells incubated with title comp. for 24 to 72 h; amount of DNA which is related to the number of cells detd.

Citation

Assay Description

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Cytotoxic

Target : WB-F344 rat liver epithelial cells Bioassay : DMEM with 10 percent FBS; humidified 5 percentCO2/95 percent air; 37 deg C; incubated for 48 h without or with bovine liver catalase (100 Sigma units/ml); 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide colorimetric assay

Results

title comp. inhibited cell proliferation in conc.-dependent manner at 12.5 μg/ml and more and exhibited cytotoxicity of 54 percent at 25 μg/ml; title comp. cytotoxicity was in part abolished by addition of catalase

Citation

Ki, Won Lee; Haeng, Jeon Hur; Hyong, Joo Lee; Chang, Yong Lee

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 6 p. 1990 - 1995 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic


Assay Description

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Results

title comp. produced complete inhibition of GJIC and this effect was in part abolished by addition of catalase

Citation

Ki, Won Lee; Haeng, Jeon Hur; Hyong, Joo Lee; Chang, Yong Lee

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 6 p. 1990 - 1995 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human Caco-2

Assay Description

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Target : WB-F344 rat liver epithelial cells Bioassay : effect on gap-junction intercellular communication (GJIC) evaluated by scrape loading/dye-transfer method; DMEM with 10 percent FBS; humidified 5 percentCO2/95 percent air; 37 deg C; incubated for 1 h without or with bovine liver catalase (100 Sigma units)

Bioassay : DMEM with 10 percent FBS; humidified 5 percentCO2/95 percent air; 37 deg C; incubated for 48 h without or with bovine liver catalase (100 Sigma units/ml); 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide colorimetric assay

Results

title comp. inhibited cell proliferation in conc.-dependent manner at 12.5 μg/ml and more and exhibited cytotoxicity of 75 percent at 25 μg/ml; title comp. cytotoxicity was in part abolished by addition of catalase

Citation

Ki, Won Lee; Haeng, Jeon Hur; Hyong, Joo Lee; Chang, Yong Lee

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 6 p. 1990 - 1995 Title/Abstract Full Text View citing articles Show Details

Biological material

PC12

Assay Description

Effect : H2O2-induced mitochondrial depolarization flow cytometry; PC12: rat pheochromocytoma cell line

Citation

Crispo, James A.G.; Piche, Matthew; Ansell, Dominique R.; Eibl, Joseph K.; Tai, Isabella T.; Kumar, Aseem; Ross, Gregory M.; Tai

Biochemical and Biophysical Research Communications, 2010 , vol. 393, # 4 p. 773 - 778 Title/Abstract Full Text View citing articles Show Details

Target

Sucrose phosphorylase:Wild

Biological material

Leuconostoc mesenteroides

Assay Description

Effect : transglucosylation activity enzyme activity Species : Leuconostoc mesenteroides ATTC 12291 Bioassay : sucrose phosphorylase LmSP2: L. mesenteroides ATTC 12291 sucrose phosphorylase; hydrolysis rate determined as reference to water hydrolysis; bicinchoninic acid assay

Results

hydrolysis rate 0.65

Citation

Aerts, Dirk; Verhaeghe, Tom F.; Roman, Bart I.; Stevens, Christian V.; Desmet, Tom; Soetaert, Wim

Carbohydrate Research, 2011 , vol. 346, # 13 p. 1860 - 1867 Title/Abstract Full Text View citing articles Show Details

Target

Sucrose phosphorylase:Wild

Biological material

Leuconostoc mesenteroides

Assay Description

Effect : transglucosylation activity enzyme activity Species : Leuconostoc mesenteroides NRRL B1355 Bioassay : sucrose phosphorylase LmSP3: L. mesenteroides NRRL B1355 sucrose phosphorylase; hydrolysis rate determined as reference to water hydrolysis; bicinchoninic acid assay

Results

hydrolysis rate 0.3

Citation

Aerts, Dirk; Verhaeghe, Tom F.; Roman, Bart I.; Stevens, Christian V.; Desmet, Tom; Soetaert, Wim

Carbohydrate Research, 2011 , vol. 346, # 13 p. 1860 - 1867


Title/Abstract Full Text View citing articles Show Details

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Biological material

Lactobacillus acidophilus

Assay Description

Effect : transglucosylation activity enzyme activity Target : LaSP Bioassay : sucrose phosphorylase LaSP: L. acidophilus LMG 9433 sucrose phosphorylase; hydrolysis rate determined as reference to water hydrolysis; bicinchoninic acid assay

Results

hydrolysis rate 0.18

Citation

Aerts, Dirk; Verhaeghe, Tom F.; Roman, Bart I.; Stevens, Christian V.; Desmet, Tom; Soetaert, Wim

Carbohydrate Research, 2011 , vol. 346, # 13 p. 1860 - 1867 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : scavenging activity Bioassay : DPPH radical DPPH: 2,2-diphenyl-1-picrylhydrazyl

Results

ARP anti-radical power 12.5

Citation

Arteaga, Jesus F; Ruiz-Montoya, Mercedes; Palma, Alberto; Alonso-Garrido, Gema; Pintado, Sara; Rodriguez-Mellado, Jose M

Molecules (Basel, Switzerland), 2012 , vol. 17, # 5 p. 5126 - 5138 Title/Abstract Full Text Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : 1,1-diphenyl-2-picrylhydrazyl

Results

SC50 radical-scavenging activity 10.7 μmol/l

Citation

She, Gai-Mei; Zhang, Ying-Jun; Yang, Chong-Ren

Chemistry and Biodiversity, 2009 , vol. 6, # 6 p. 875 - 880 Title/Abstract Full Text View citing articles Show Details

Effect

Anticoagulant

Biological material

human

Assay Description

Effect : anticoagulant Bioassay : plasma

Citation

Correia-Da-Silva, Marta; Sousa, Emilia; Duarte, Barbara; Marques, Franklim; Cunha-Ribeiro, Luis M.; Pinto, Madalena M.M.

European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2347 - 2358 Title/Abstract Full Text View citing articles Show Details

Target

Prolyl endopeptidase [Elizabethkingia meningoseptica]:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : in vitro

Results

title comp. inhibited enzyme activity by 33.0 percent

Citation

Wenzhe, Fan; Tezuka, Yasuhiro; Kadota, Shigetoshi

Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 7 p. 1055 - 1061 Title/Abstract Full Text View citing articles Show Details


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Results

no activity against Escherichia Coli B and B. stearothermophilis ATCC 12980

Citation

Serit, Muney; Okubo, Tsutomu; Su, Rong-Hui; Hagiwara, Nobuyuki; Kim, Mujo; et al.

Agricultural and Biological Chemistry, 1991 , vol. 55, # 1 p. 19 - 23 Title/Abstract Full Text Show Details

Results

antibacterial activity: Bacillus subtilis, MIC=71.3 μg/ml; Staphylococcus aureus, MIC=71.3 μg/ml

Citation

Majinda, Runner R. T.; Motswaledi, Modisa; Waigh, Roger D.; Waterman, Peter G.

Planta Medica, 1997 , vol. 63, # 3 p. 268 - 270 Title/Abstract Full Text View citing articles Show Details

Biological material

Mus musculus 3T3-L1 cell line

Assay Description

Effect : adiponectin expression; effect on Bioassay : 3T3-L1 differentiated adipocytes Example 1: Enhancement of adiponectin expression by (-)-catechin in adipocytesStep 1) Adipocyte DifferentiationMouse 3T3-L1 (ATCC No. CL 173) preadipocyte cells were incubated in DMEM (Dulbecco's modified Eagle's Medium, Gibco 1210-0038) containing 10% calf serum in 10% CO2 incubator, while

Citation

CHO, Si Young; PARK, Pil Joon; SHIN, Hyun Jung; KIM, Young-Kyung; SHIN, Dong Wook; SHIN, Euiseok; LEE, Hyoung Ho; LEE, Byeong Gon; BAIK, Joo-Hyun; LEE, Tae Ryong

Patent: WO2007/126293 A1, 2007 ; Title/Abstract Full Text Show Details

Assay Description

Effect : the growth of Gardnerella vaginalis; inhibiion of Target : ATCC #14018 of Gardnerella vaginalis Bioassay : The ability of the vaginal treatment composition of the present invention to inhibit and/or treat vaginal infection was demonstrated. Initially, eight (8) solutions were formed as set forth below in Table 8. Samples 1-2 were prepared by dissolving the KELCOGEL® (0.07 grams) and/or xylitol (0.44

Results

The test compound exhibited inhibition for Gardnerella vaginalis growth, average plate count - 3.43 × 104 .

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2006/105963 A1, 2006 ; Title/Abstract Full Text Show Details

Target

enzyme:Wild

Assay Description

Effect : enzyme; inhib. of Bioassay : enzyme from cell-free extracts of the strain Pseudomonas sp. RW31 after growth with 4-sulfophthalate or phthalate

Results

Ki = 7.4 μM (exctract of cells grown with 4-sulfophthalate); Ki = 7.6 μM (extract of cells grown with phthalate); competitive inhibition

Citation

Richter; Wittich

Biodegradation, 1994 , vol. 5, # 1 p. 63 - 69 Title/Abstract Full Text View citing articles Show Details

Effect

Toxic

Assay Description

179 of 515

Target : Salvinia molesta Mitchell, free-floating fern Bioassay : outdoor conditions effect on the number of healthy fronds (HFN) and biomass

Citation

Pandey, D. K.

Journal of Chemical Ecology, 1994 , vol. 20, # 12 p. 3111 - 3122 Title/Abstract Full Text View citing articles Show Details

Biological material

pig

Assay Description

Effect : |transmitter releasing Bioassay : control: vehicle; 15 nmol/l substance P as reference comp. (100 percent); NO: nitric oxide; further investigation with NG-monomethyl-L-arginine (L-NMMA), inhibitor of NO synthase artery (2 cm) mounted in organ bath (10 ml, 25 deg C), then increasing conc. of title comp. added; nitric oxide release monitored amperometrically in real time by NO-selective microsensor


180 of 515

Results

title comp. elicited nonsign. increase of endothelial NO release: Emax = 32.9 percent and pD2 = 6.86; after pretreatment with L-NMMA effect of title comp. did not change sign.: Emax = 30.2 and pD2 = 6.78 (table)

Citation

Taubert, Dirk; Berkels, Reinhard; Klaus, Wolfgang; Roesen, Renate

Journal of Cardiovascular Pharmacology, 2002 , vol. 40, # 5 p. 701 - 713 Title/Abstract Full Text View citing articles Show Details

Effect

Inflammatory

Assay Description

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Target : murine RAW 264.7 macrophages Bioassay : iNOS: inducible nitric-oxide synthase; COX: cyclooxygenase iNOS and COX-2 expression studied by Western blotting after 6 h of title comp. treatment

Citation

Rapizzi, Elena; Fossati, Silvia; Moroni, Flavio; Chiarugi, Alberto

Molecular Pharmacology, 2004 , vol. 66, # 4 p. 890 - 898 Title/Abstract Full Text View citing articles Show Details

Effect

Phytotoxic

Assay Description

Effect : ion uptake Target : Cucumis sativus L. Tokiwa, cucumber Bioassay : index (R) for ion uptake inhibition: R = 100(k0 - k)/k0, where k is the rate of ion uptake per unit of fresh weight of root, calculated from changes in the amount of the ions in the solution before and after incubation; k0 is k for the control 15- to 17-day-old seedlings; nutrient solution; pH 5.5; growth chamber; 7500 Lx; 25 deg C

Results

inhibition index (R) for NO3(-): 8, H2PO4(-): -21, SO4(2-): 61, K(+): 30, Ca(2+): 38, Mg(2+): -3

Citation

Yu, Jing Quan; Matsui, Yoshihisa

Journal of Chemical Ecology, 1997 , vol. 23, # 3 p. 817 - 827 Title/Abstract Full Text View citing articles Show Details

Biological material

human HEK293 cell line

Assay Description

Effect : gene expression; effect on Bioassay : PPAR-α: peroxisome proliferator-activated receptor-α cells transfected with PPAR-α reporter gene and tK-PPREx3-Luc plasmid; incubation in DMEM/F-12 with title comp.; after 24 h cells were lysed, and PPAR-α acrivity was determined; luciferase assay

Citation

Huang, Tom Hsun-Wei; Peng, Gang; Kota, Bhavani Prasad; Li, George Qian; Yamahara, Johji; Roufogalis, Basil D.; Li, Yuhao

British Journal of Pharmacology, 2005 , vol. 145, # 6 p. 767 - 774 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : LPS: lipopolysaccharide; iNOS: inducible nitric oxide synthase macrophages treated with 5 μg/ml LPS and title comp. for 18 h; total protein extracted, iNOS protein determiend by Western blotting; α-tubulin and nitrite also assayed

Results

title comp. reduced iNOS protein by 92 percent

Citation

Lin, Yu-Li; Lin, Jen-Kun

Molecular Pharmacology, 1997 , vol. 52, # 3 p. 465 - 472 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : inhibition of C24Δ6 desaturation

Results

desaturation index = 0.13

Citation

Nakano; Shirasaka; Koyama; Hino; Murakami; Shimizu; Yoshizumi

Bioscience, biotechnology, and biochemistry, 2000 , vol. 64, # 8 p. 1641 - 1650


Title/Abstract Full Text View citing articles Show Details

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186 of 515

187 of 515

Biological material

Rattus norvegicus

Assay Description

Effect : inhibition of Δ5 desaturation

Results

desaturation index = 0.46

Citation

Nakano; Shirasaka; Koyama; Hino; Murakami; Shimizu; Yoshizumi

Bioscience, biotechnology, and biochemistry, 2000 , vol. 64, # 8 p. 1641 - 1650 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : inhibition of Δ6 desaturation

Results

desaturation index = 3.40

Citation

Nakano; Shirasaka; Koyama; Hino; Murakami; Shimizu; Yoshizumi

Bioscience, biotechnology, and biochemistry, 2000 , vol. 64, # 8 p. 1641 - 1650 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

188 of 515

Results

SAA (μmol-1*l): 750 and 100 (for Cu(2+) oxidation) and 90 and 30 (for 2,2'-azobis(2-aminopropane) hydrochloride oxidation) at concentration 0.2 and 1 μmol LDL, respectively

Citation

Cartron, Emeline; Carbonneau, Marie-Annette; Fouret, Gilles; Descomps, Bernard; Leger, Claude L.

Journal of Natural Products, 2001 , vol. 64, # 4 p. 480 - 486 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

189 of 515

Target : human low-density lipoprotein Bioassay : low-density lipoprotein (LDL) (0.2 or 1 μmol/l) in PBS buffer; title compound inhibited with Cu(2+) (5 μmol/l) or AAPH (2.5 μmol/l) at 37 deg C for 1 h; production of conjugated dienes assessed; specific antioxidant activity (SAA) measured

Target : erythrocytes of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride erythrocyte suspension at 5% hematocrit preincubated with title comp. for 30 min at 37 deg C followed by incubation with AAPH (25 mmol/l) in phosphate buffered saline (pH 7.4) for up to 6 h at 37 deg C; hemolysis of erythrocytes determined

Results

title comp. decreased AAPH-induced hemolysis; fig.

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Target : erythrocytes of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride erythrocyte suspension at 5% hematocrit preincubated with title comp. for 30 min at 37 deg C followed by incubation with AAPH (25 mmol/l) in phosphate buffered saline (pH 7.4) for 6 h at 37 deg C and superoxide dismutase (SOD) in cells measured

Results

title comp. decreased AAPH-induced decrease in SOD content; table

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details


190 of 515

Effect Assay Description

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title comp. in dose-depend. manner decreased AAPH-induced MDA formation; table

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

title comp. at conc. of 10-50 μg/ml decreased CuSO4-induced oxidation of lipoprotein; fig.

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target : low density lipoprotein of human Bioassay : lipoprotein (200 μg protein/ml) oxidized by sodium nitroprusside (75 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein assayed using electrophoretic mobility analysis

Results

title comp. decreased sodium nitroprusside-induced oxidation of lipoprotein; fig.

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

194 of 515

Target : low density lipoprotein of human Bioassay : lipoprotein (200 μg protein/ml) oxidized by CuSO4 (20 μmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein assayed using electrophoretic mobility analysis

Results

Assay Description

193 of 515

Target : erythrocytes of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride; MDA: malondialdehyde erythrocyte suspension at 5% hematocrit preincubated with title comp. for 30 min at 37 deg C followed by incubation with AAPH (25 mmol/l) in phosphate buffered saline (pH 7.4) for 6 h at 37 deg C; lipid peroxidation assayed by MDA measurement

Results

Assay Description

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Antioxidant

Target : low density lipoprotein of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride lipoprotein (200 μg protein/ml) oxidized by AAPH (3 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein assayed using electrophoretic mobility analysis

Results

title comp. at conc. of 30 and 50 μg/ml decreased AAPH-induced oxidation of lipoprotein; fig.

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Target : low density lipoprotein of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride; reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml) lipoprotein (200 μg protein/ml) oxidized by AAPH (3 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using determination of total cholesterol and assessment of cholesterol degradation

Results

title comp. decreased AAPH-induced cholesterol degradation; effect of title comp. was similar to that of trolox; table

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114


Title/Abstract Full Text View citing articles Show Details

195 of 515

Effect Assay Description

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title comp. decreased AAPH-induced oxidation of lipoprotein; effect of title comp. was similar to that of trolox; table

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

title comp. decreased CuSO4-induced cholesterol degradation; effect of title comp. was stronger than that of reference comp.; table

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target : low density lipoprotein of human Bioassay : reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml); TBARS: thiobarbituric acid reactive substances lipoprotein (200 μg protein/ml) oxidized by CuSO4 (20 μmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using TBARS formation assay

Results

title comp. decreased CuSO4-induced oxidation of lipoprotein; effect of title comp. was stronger than that of reference comp.; table

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

199 of 515

Target : low density lipoprotein of human Bioassay : reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml) lipoprotein (200 μg protein/ml) oxidized by CuSO4 (20 μmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using determination of total cholesterol and assessment of cholesterol degradation

Results

Assay Description

198 of 515

Target : low density lipoprotein of human Bioassay : AAPH: 2,2'-azo-bis(2-amidinopropane) hydrochloride; reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml); TBARS: thiobarbituric acid reactive substances lipoprotein (200 μg protein/ml) oxidized by AAPH (3 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using TBARS formation assay

Results

Assay Description

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Antioxidant

Target : low density lipoprotein of human Bioassay : reference comp.: vitamin C (50 μg/ml) and trolox (50 μg/ml); TBARS: thiobarbituric acid reactive substances lipoprotein (200 μg protein/ml) oxidized by sodium nitroprusside (75 mmol/l) in presence of title comp. for 20 h at 37 deg C in dark; oxidation of lipoprotein determined using TBARS formation assay

Results

title comp. decreased sodium nitroprusside-induced oxidation of lipoprotein; effect of title comp. was similar to that of trolox; table

Citation

Hseu, You-Cheng; Chang, Wen-Huei; Chen, Chee-Shan; Liao, Jiunn-Wang; Huang, Chin-Jung; Lu, Fung-Jou; Chia, Yi-Chen; Hsu, Hseng-Kuang; Wu, Jia-Jiuan; Yang, Hsin-Ling

Food and Chemical Toxicology, 2008 , vol. 46, # 1 p. 105 - 114 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

Results

Target : rat hepatoma dRLh-84 cells Bioassay : further study with Ca(2+) chelator BAPTA-AM, calmodulin inhibitor W-7, EGTA, Ca(2+) channel blocker verapamil, calpeptin, NADPH oxidase inhibitor DPhI cells incubated with title comp. for 6 h; cell viability determined by MTT assay title comp. completely killed cells after 6 h incubation; BAPTA-AM abrogated title comp.-induced cell death; W-7, EGTA inhibited cell death; verapamil, calpeptin and DPhI failed to show inhibitory activity


against title comp.-induced cell death; fig.

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Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human PLC/PRF/5 cell line

Assay Description

201 of 515

Results

title comp. completely killed the cells after 6 h incubation; BAPTA-AM abrogated title comp.-induced cell death; W-7, EGTA hd no effect; verapamil, calpeptin and DPhI failed to show inhibitory activity against title comp.-induced cell death; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human HtTA-1 cell line

Assay Description

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Bioassay : further study with Ca(2+) chelator BAPTA-AM, calmodulin inhibitor W-7, EGTA, Ca(2+) channel blocker verapamil, calpeptin, NADPH oxidase inhibitor DPhI cells incubated with title comp. for 6 h; cell viability determined by MTT assay

Bioassay : further study with Ca(2+) chelator BAPTA-AM, calmodulin inhibitor W-7, EGTA, Ca(2+) channel blocker verapamil, calpeptin, NADPH oxidase inhibitor DPhI cells incubated with title comp. for 6 h; cell viability determined by MTT assay

Results

title comp. completely killed the cells after 6 h incubation; BAPTA-AM abrogated title comp.-induced cell death; W-7, EGTA hd no effect; verapamil, calpeptin and DPhI failed to show inhibitory activity against title comp.-induced cell death; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : cell cycle distribution; effect on Target : human promyelocytic leukemia HL-60RG cells Bioassay : cells cultured in RPMI-1640 medium; incubated with title comp. for 2 or 6 h; DNA content in each cell cycle phase analysed by flow cytometry method (FACScan)

Results

flow cytometric analyses revealed that smaller DNA, which resulted from DNA degradation was detected in cells at 2 h after treatment with title comp. and cell cycle distribution was not changed during the incubation period; figure

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : cell cycle distribution; effect on Target : rat hepatoma dRLh-84 cells Bioassay : cells cultured in RPMI-1640 medium; incubated with title comp. for 2 or 6 h; DNA content in each cell cycle phase analysed by flow cytometry method (FACScan)

Results

appearance of DNA with low fluorescent intensity was not observed after title comp. treatment; cell cycle distributions were not changed during the incubation period; figure

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

Target : rat hepatoma dRLh-84 cells Bioassay : further study with N-acetyl-L-cysteine (NAC), catalase and ascorbic acid cells incubated with title comp. for 6 h; cell viability determined by MTT assay


205 of 515

Results

title comp. completely killed the cells after 6 h incubation; NAC and catalase protected against title comp.-induced cell death; ascorbic acid abolished the death of cells; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

206 of 515

Results

title comp. completely killed the cells after 6 h incubation; H-7, H-89 and genistein failed to protect against title comp.-induced cell death or showed only a weak stimulatory or inhibitory effect that was not significant; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human PLC/PRF/5 cell line

Assay Description

207 of 515

Bioassay : further study with N-acetyl-L-cysteine (NAC), catalase and ascorbic acid cells incubated with title comp. for 6 h; cell viability determined by MTT assay

Results

title comp. completely killed the cells after 6 h incubation; NAC and catalase protected against title comp.-induced cell death; ascorbic acid abolished the death of PLC/PRF/5 cells; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human PLC/PRF/5 cell line

Assay Description

208 of 515

Target : rat hepatoma dRLh-84 cells Bioassay : further study with protein kinase C inhibitor H-7, protein kinase A inhibitor H-89 and tyrosine kinase inhibitor genistein cells incubated with title comp. for 6 h; cell viability determined by MTT assay

Bioassay : further study with protein kinase C inhibitor H-7, protein kinase A inhibitor H-89 and tyrosine kinase inhibitor genistein cells incubated with title comp. for 6 h; cell viability determined by MTT assay

Results

title comp. completely killed the cells after 6 h incubation; H-7, H-89 and genistein failed to protect against title comp.-induced cell death or showed only a weak stimulatory or inhibitory effect that was not significant; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human HtTA-1 cell line

Assay Description

Bioassay : further study with N-acetyl-L-cysteine (NAC), catalase and ascorbic acid cells incubated with title comp. for 6 h; cell viability determined by MTT assay

Results

title comp. completely killed the cells after 6 h incubation; NAC and catalase protected against title comp.-induced cell death; ascorbic acid slightly stimulated death of cells; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details


209 of 515

Effect

Cytotoxic

Biological material

human HtTA-1 cell line

Assay Description

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Results

title comp. completely killed the cells after 6 h incubation; H-7, H-89 and genistein failed to protect against title comp.-induced cell death or showed only a weak stimulatory or inhibitory effect that was not significant; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Biological material

human PLC/PRF/5 cell line

Assay Description

Effect : cell cycle distribution; effect on Bioassay : cells cultured in RPMI-1640 medium; incubated with title comp. for 2 or 6 h; DNA content in each cell cycle phase analysed by flow cytometry method (FACScan)

Results

appearance of DNA with low fluorescent intensity was not observed after title comp. treatment; cell cycle distributions were not changed during the incubation period; figure

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Biological material

human HtTA-1 cell line

Assay Description

Effect : cell cycle distribution; effect on Bioassay : cells cultured in RPMI-1640 medium; incubated with title comp. for 2 or 6 h; DNA content in each cell cycle phase analysed by flow cytometry method (FACScan)

Results

appearance of DNA with low fluorescent intensity was not observed after title comp. treatment; cell cycle distributions were not changed during the incubation period; figure

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

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Bioassay : further study with protein kinase C inhibitor H-7, protein kinase A inhibitor H-89 and tyrosine kinase inhibitor genistein cells incubated with title comp. for 6 h; cell viability determined by MTT assay

Target : xanthine oxidase Bioassay : negative control: 100% DMSO; positive control: 600 U/ml SOD; SC50: concentration of title comp. that scavenge 50% of superoxide radicals; XO: xanthine oxidase title comp. added to mixture contg. NaHCO3 buffer (50 mmol/l), hypoxanthine (0.5 mmol/l), EDTA (1 mmol/l), and XTT (0.25 mmol/l); reaction initiated by addition of XO (200 mU/ml); reduced XTT production determined at 480 nm every 20 s for 5 min

Results

SC50 0.7 mg/l

Citation

Rangkadilok, Nuchanart; Sitthimonchai, Somkid; Worasuttayangkurn, Luksamee; Mahidol, Chulabhorn; Ruchirawat, Mathuros; Satayavivad, Jutamaad

Food and Chemical Toxicology, 2007 , vol. 45, # 2 p. 328 - 336 Title/Abstract Full Text View citing articles Show Details

Target

xanthine oxidase:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : negative control: 100% DMSO; positive control: allopurinol title comp. added to reaction mixture contg. NaHCO3 (50 mmol/l) buffer, xanthine (1 mmol/l), and EDTA (1 mmol/l); reaction initiated by addition of enzyme (200 mU/ml); rate of uric acid production immediately measured at 295 nm every 20 s for 5 min

Results

title comp. inhibited xanthine oxidase by 21%

Citation

Rangkadilok, Nuchanart; Sitthimonchai, Somkid; Worasuttayangkurn, Luksamee; Mahidol, Chulabhorn; Ruchirawat, Mathuros; Satayavivad, Jutamaad

Food and Chemical Toxicology, 2007 , vol. 45, # 2 p. 328 - 336 Title/Abstract Full Text View citing articles Show Details


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Effect

Pesticidal

Biological material

Meloidogyne incognita

Assay Description

Effect : nematicidal Bioassay : larva

Results

maximal mortality at 0.5% 92 %

Citation

Sultana, Nighat; Akhter, Musarrat; Khatoon, Zakia

Natural Product Research, 2010 , vol. 24, # 5 p. 407 - 415 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : free radical scavenging Bioassay : 2,2-diphenyl-1-picrylhydrazyl colorimetric method

Results

SC50 scavenging concentration 5.17 μmol

Citation

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

Biological material

murine cells

Assay Description

Effect : α-MSH-induced melanin production spectrophotometric assay

Results

melanin content 68.8 percent

Citation

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Species : not explicitly stated by authors ferric reducing antioxidant power (FRAP) assay; AEAC: ascorbic acid equivalent antioxidant capacity

Results

AEAC 21.267 mg/ml

Citation

Gourine, Nadhir; Yousfi, Mohamed; Bombarda, Isabelle; Nadjemi, Boubakeur; Gaydou, Emile

JAOCS, Journal of the American Oil Chemists' Society, 2010 , vol. 87, # 2 p. 157 - 166 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : LOX-1 hydroperoxidative activity Bioassay : RNO and linoleic acid RNO: 4-nitroso-N,N-dimethylaniline; LOX-1: lipoxygenase-1 isoenzyme

Results

percent increase in lag phase 22 %

Citation

Pastore, Donato; Laus, Maura N.; Tozzi, Damiana; Fogliano, Vincenzo; Soccio, Mario; Flagella, Zina

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 20 p. 9682 - 9692 Title/Abstract Full Text View citing articles Show Details


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Effect

Antioxidant

Assay Description

Effect : free radical scavenging Target : 2,2-diphenyl-1-picrylhydrazyl radical Bioassay : 2,2-diphenyl-1-picrylhydrazyl radical time of test: 30 min

Results

scavenging rate 23 - 99.2 percent

Citation

Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details

Effect

Antihemolytic

Biological material

human erythrocyte

Assay Description

Effect : AAPH-induced hemolysis AAPH: 2,2'-azobis(2-amidinopropane) hydrochloride; effect determined after 3 h; control: 17%

Results

hemolysis rate 3 percent

Citation

Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details

Effect

Antihemolytic

Biological material

human erythrocyte

Assay Description

Effect : AAPH-induced hemolysis AAPH: 2,2'-azobis(2-amidinopropane) hydrochloride; effect determined after 6 h; hemolysis rate at conc. of 200 μmol/l: 72%; control: 78%

Citation

Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details

Effect

Antihemolytic

Biological material

human erythrocyte

Assay Description

Effect : cumene hydroperoxide-induced hemolysis time of test: 2 h; control: 72.9%; hemolysis rate at 10 μmol/l: 67%

Results

hemolysis rate 17 percent

Citation

Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details

Effect

Hemolytic

Biological material

human erythrocyte

Assay Description

Effect : hemolysis hemolysis rate: 4.7%; effect determined after 6 h; control hemolysis rate: 3.7%

Citation

Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details


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Biological material

human erythrocyte

Assay Description

Effect : AAPH-induced intracellular GSH depletion AAPH: 2,2'-azobis(2-amidinopropane) hydrochloride; time of test: 2 h; GSH intracellular level: 4.5 μmol/lg Hb; GSH: glutathione; DTNB method; positive control: 4.2 μmol/lg Hb

Citation

Ximenes, Valdecir F.; Lopes, Mariana G.; Petronio, Maicon Segalla; Regasini, Luis Octavio; Siqueira Silva, Dulce H.; Da Fonseca, Luiz M.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5355 - 5362 Title/Abstract Full Text View citing articles Show Details

Effect

Antidiabetic

Biological material

Rattus norvegicus

Assay Description

Effect : sugar level Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg)

Citation

Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

Rattus norvegicus

Assay Description

Effect : malondialdehyde level Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg)

Citation

Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : incidence of cataract eye injury Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg); hematoxylin-eosin staining, light microscopy

Citation

Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : insulin level hormone release Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg)

Citation

Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : islets injury pancreas injury Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg); hematoxylin-eosin staining, light microscopy


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Citation

Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : microaneurysm in lenses eye injury Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg); hematoxylin-eosin staining, light microscopy

Citation

Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : tumor formation Species : Sprague-Dawley rat diabetes induced by streptozotocin (i.p., 50 mg/kg); hematoxylin-eosin staining, light microscopy

Citation

Hsieh, Chiu-Lan; Peng, Chiung-Chi; Cheng, Yu-Ming; Lin, Li-Yun; Ker, Yaw-Bee; Chang, Chi-Huang; Chen, Kuan-Chou; Peng, Robert Y.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 16 p. 9273 - 9280 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : calcium uptake; effect on Target : rat pituitary GH4C1 cells Bioassay : BSS: buffered salt solution; vehicle control; reference comp.: verapamil (IC50 = 3.0 μg/ml) cells incubated with BSS containing title comp., 50 mmol/l K(1+) and 45Ca(2+) at 37 deg C, for 15 min; washed; calcium uptake via voltage-operated calcium channels measured as radioactivity by liquid scintillation counting

Citation

Summanen, Jari; Vuorela, Pia; Rauha, Jussi-Pekka; Tammela, Paeivi; Marjamaeki, Krista; Pasternack, Michael; Toernquist, Kid; Vuorela, Heikki

European Journal of Pharmacology, 2001 , vol. 414, # 2-3 p. 125 - 133 Title/Abstract Full Text View citing articles Show Details

Target

Estrogen receptor beta:Wild

Assay Description

Effect : |receptor; binding activity Bioassay : competition binding assay with radiolabeled estradiol as radioligand

Citation

Mallavadhani, Uppuluri Venkata; Narasimhan, Kilambi; Sudhakar, Akella Venkata Subrahmanya; Mahapatra, Anita; Li, Wenkui; Van Breemen, Richard Bruce

Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 5 p. 740 - 744 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |receptor; binding activity Target : estrogen receptor-α Bioassay : competition binding assay with radiolabeled estradiol as radioligand

Citation

Mallavadhani, Uppuluri Venkata; Narasimhan, Kilambi; Sudhakar, Akella Venkata Subrahmanya; Mahapatra, Anita; Li, Wenkui; Van Breemen, Richard Bruce

Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 5 p. 740 - 744 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : calcium deposition; increase of Target : pre-osteoblastic cell line MC3T3-E1 of mouse Bioassay : Following Experiment 1 which investigates differentiating pre-osteoblastic cells into osteoblastic cells, some of organic compounds were investigated whether they actually enhance calcium deposition or not. Indomethacin (commercialized by Funakoshi, Co., Ltd., Tokyo, Japan) (positive control), kaempferol

Citation

Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo

Patent: EP1514540 A1, 2005 ; Title/Abstract Full Text Show Details

Target

alkaline phosphatase:Wild


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Assay Description

Effect : alkaline phosphatase; induction of Bioassay : Culturing mouse pre-osteoblastic cells Mouse pre-osteoblastic cell line MC3T3-E1 was suspended in α-MEM medium (pH6.8) supplemented with 10mM HEPES and 10(v/v)% calf serum albumin (produced by Gibco BRL Company), which contains the ingredients listed in Table 7 to be concentration of 5×104

Citation

Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo

Patent: EP1514540 A1, 2005 ; Title/Abstract Full Text Show Details

Assay Description

Effect : Herpes simplex virus (HSV) infection; effect on Target : with Herpes simplex virus (HSV) infection of human Bioassay : Example 7 External Treatment of HSV Infection in Clinical Tests Twenty-two patients who were clinically diagnosed with HSV infection were randomly selected and divided into two groups. Acyclovir ointment and micro emulsion containing propyl gallate prepared as described in Example 1 were applied to

Results

treatment with a microemulsion containing the title compound was more effective than treatment with acyclovir; treatment with title compound-containing microemulsion gave an average time for recovery of 3 days compared with average recovery time of

Citation

Weihua, QIN

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antiviral

Assay Description

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Results

no Human papillomavirus HPV 6/11 virus remained 24 hours after treatment with 50 µl micro emulsion containing 10 % of title compound

Citation

Weihua, QIN

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antiviral

Assay Description

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Target : Human papillomavirus 6/11 Bioassay : Example 4 Drug Screening Through Quantitative Fluorescent PCR Analysis Samples The test compounds listed in Table 1 below were prepared as micro emulsions as described in Example 1. Saline water was used as the control. Methyl 2,3,4-trihydroxybenzoate was prepared as follows: 10 g of 2,3,4-trihydroxybenzoic

Target : Human papillomavirus 6/18 Bioassay : Example 4 Drug Screening Through Quantitative Fluorescent PCR Analysis Samples The test compounds listed in Table 1 below were prepared as micro emulsions as described in Example 1. Saline water was used as the control. Methyl 2,3,4-trihydroxybenzoate was prepared as follows: 10 g of 2,3,4-trihydroxybenzoic

Results

no Human papillomavirus HPV 6/18 virus remained 24 hours after treatment with 50 µl micro emulsion containing 10 % off title compound

Citation

Weihua, QIN

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

Hep-G2/2.2.15 cell line

Assay Description

Effect : HBeAg secretion; inhibition of Bioassay : Example 6 Inhibition Effect of Hydroxybenzoic Acid Ester Analogue on Secretion of HBsAg and HBeAg by Hepatitis B 2.2.15 Cell Line Experiment Materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological

Results

treatment with 2 µmol/ml title compound gave an inhibition rate of 9.4%

Citation

Weihua, QIN

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

Hep-G2/2.2.15 cell line

Assay Description

Effect : HBsAg secretion; inhibition of Bioassay : Example 6 Inhibition Effect of Hydroxybenzoic Acid Ester Analogue on Secretion of HBsAg and HBeAg by Hepatitis B 2.2.15 Cell Line Experiment Materials Hepatitis B 2.2.15 cell line was


transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological

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Results

treatment with 2 µmol/ml title compound gave an inhibition rate of 8.3%

Citation

Weihua, QIN

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

human

Assay Description

Effect : condyloma acuminata; effect on Bioassay : Example 5 Clinical Use of Hydroxybenzoic Acid Ester in Treating Condyloma Acuminata Diagnosis Standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of Health

Results

treatment with title compound had more apparent treatment effect compared with recombinant human interferon α-2β gel; treatment with title compound showed that in 4 patients more than 70% of skin lesions disappeared after 1-8 days, 4 patients

Citation

Weihua, QIN

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : HBeAg secretion; inhibition of Target : liver 2.2.15 cells transfected by hepatitis B virus (HBV) DNA Bioassay : Example 6. Inhibition effect of hydroxybenzoic acid ester analogue on secretion of HBsAg by hepatitis B 2.2.15 cell line Experiment materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological Sciences

Results

treatment with the title compound at 2μmol/ml inhibited the rate of HBeAg secretion measured as 9.40% inhibition rate (control=0%)

Citation

QIN, Weihua, F/22 NorthTower

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : HBsAg secretion; inhibition of Target : liver 2.2.15 cells transfected by hepatitis B virus (HBV) DNA Bioassay : Example 6. Inhibition effect of hydroxybenzoic acid ester analogue on secretion of HBsAg by hepatitis B 2.2.15 cell line Experiment materials Hepatitis B 2.2.15 cell line was transfected by HBV DNA (purchased from Institute of Biochemistry and Cell Biology of Shanghai Institute for Biological Sciences

Results

treatment with the title compound at 2μmol/ml inhibited the rate of HBsAg secretion measured as 8.83% inhibition rate (control=0%)

Citation

QIN, Weihua, F/22 NorthTower

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antiviral

Assay Description

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Target : Human papillomavirus (HPV) 16/18 Bioassay : Example 4. Drug screening through quantitative fluorescent PCR analysis Samples The micro emulsions obtained in Example 1 were used as test samples, and saline water was used as the control. HPV samples: condyloma acuminata samples were taken from clinical patients. The samples were washed with saline

Results

treatment with the title compound at 50μl micro emulsion effectively and rapidly eliminated the number of human papillomavirus (HPV) 16/18 from 1.40E5 (control) to 0copies/ml

Citation

QIN, Weihua, F/22 NorthTower

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antiviral

Assay Description

Target : Human papillomavirus (HPV) 6/11 Bioassay : Example 4. Drug screening through quantitative fluorescent PCR analysis Samples The micro emulsions obtained in Example 1 were used as test samples, and saline water was used as the control. HPV samples: condyloma acuminata samples were taken from clinical patients. The samples were washed with saline


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Results

treatment with the title compound at 50μl micro emulsion effectively and rapidly eliminated the number of human papillomavirus (HPV) 6/11 from 1.45E6 (control) to 0copies/ml

Citation

QIN, Weihua, F/22 NorthTower

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

human

Assay Description

Effect : adverse effect Bioassay : Example 5. Clinical use of hydroxybenzoic acid ester in treating condyloma acuminata Diagnosis standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of

Results

treatment with the title compound did not cause any obvious skin irritation however some patients ocassionally experienced a burning sense

Citation

QIN, Weihua, F/22 NorthTower

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

human

Assay Description

Effect : condyloma acuminata; effect on Bioassay : Example 5. Clinical use of hydroxybenzoic acid ester in treating condyloma acuminata Diagnosis standards The following standards were taken from the Handbook for Venereal Disease Prevention and Treatment, the second edition, published by the Health and Epidemic Prevention Bureau of the Ministry of

Results

treatment with the title compound showed that in 50 qualified patients, 2 had recovered within 1-4 days, obvious effects were seen in 3 (1-4 days) and 1 (5-8 days) patient, 4 patients had improved effect

Citation

QIN, Weihua, F/22 NorthTower

Patent: EP1930002 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

human HASMC cell line

Assay Description

Effect : cholesterol efflux; stimulatory effect on Figure 10 is a graph showing the effect of active compounds from EO on efflux of cholesterol in human aortic smooth muscle cells. Confluent culture of H- ASMC in 96 well plates was incubated with [3H] cholesterol (5 μCi/ml) for 24 h. Medium was replaced with fresh medium and incubation with herbal

Results

title compound significantly induced efflux of cholesterol from cells; figure is given

Citation

THE JOHNS HOPKINS UNIVERSITY; MERLION PHARMACEUTICAL PTC LTD

Patent: WO2008/80162 A2, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : |microorganisms Target : Porcellio scaber, isopods Bioassay : adult 20-30 mg, 15 deg C, pH 5.5, feces collected, lyophilized

Results

relative consumption rates 0.02-0.04, approximate digestibility 65-86; test comp. increased number of bacteria, total microbiota counts increased in anterior hundgut

Citation

Zimmer, Martin

Journal of Chemical Ecology, 1999 , vol. 25, # 3 p. 611 - 628 Title/Abstract Full Text View citing articles Show Details

Results

protective activity against cell damage induced by active oxygens, survival 62.4percent at 100 μM, 98.6percent at 500 μM, 84.6percent at 1000 μM (singlet oxygens)

Citation

Masaki, Hitoshi; Atsumi, Takamasa; Sakurai, Hiromu

Phytochemistry (Elsevier), 1994 , vol. 37, # 2 p. 337 - 344 Title/Abstract Full Text View citing articles Show Details

Results

effect on the level of extracellular laccase activity of Botrytis cinerea


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Citation

Marbach, Irith; Harel, Eitan; Mayer, Alfred M.

Phytochemistry (Elsevier), 1983 , vol. 22, # 7 p. 1535 - 1538 Title/Abstract Full Text View citing articles Show Details

Results

in vitro DNA breaking activity

Citation

Yamada; Shirahata; Murakami; et al.

Agricultural and Biological Chemistry, 1985 , vol. 49, # 5 p. 1423 - 1428 Title/Abstract Full Text View citing articles Show Details

Effect

Antithrombotic

Biological material

rabbit thrombocyte

Assay Description

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Results

percent of platelet aggregation: 32.3

Citation

Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang

Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details

Effect

Antithrombotic

Biological material

rabbit thrombocyte

Assay Description

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Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of arachidonic acid (100 μM)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method

Results

percent of platelet aggregation: 58.9

Citation

Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang

Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details

Effect

Antithrombotic

Biological material

rabbit thrombocyte

Assay Description

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Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of arachidonic acid (100 μM)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method

Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of collagen (10 μg/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method

Results

percent of platelet aggregation: 0.0

Citation

Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang

Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details

Effect

Antithrombotic

Biological material

rabbit thrombocyte

Assay Description

Results

Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of collagen (10 μg/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method percent of platelet aggregation: 3.8


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Citation

Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang

Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details

Effect

Antithrombotic

Biological material

rabbit thrombocyte

Assay Description

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Results

percent of platelet aggregation: 14.1

Citation

Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang

Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details

Effect

Antithrombotic

Biological material

rabbit thrombocyte

Assay Description

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Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of PAF (2 ng/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method

Results

percent of platelet aggregation: 18.9

Citation

Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang

Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details

Effect

Antithrombotic

Biological material

rabbit thrombocyte

Assay Description

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Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of PAF (2 ng/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method

Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of thrombin (0.1 U/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method

Results

percent of platelet aggregation: 17.3

Citation

Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang

Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details

Effect

Antithrombotic

Biological material

rabbit thrombocyte

Assay Description

Bioassay : galloylpaeniflorin, used as positive control, caused 0.0 percent aggregation under above conditions in vitro; inhibition of thrombin (0.1 U/mL)-induced platelet aggregation determined; 4.5E8 platelets/ml; Tyrode solution with 0.35 percent BSA; platelets preincubated with title comp. for 3 min; 37 deg C; aggregation measured by turbidimetric method

Results

percent of platelet aggregation: 54.4

Citation

Ding, Hsiou-Yu; Lin, Hang-Ching; Teng, Che-Ming; Wu, Yang-Chang

Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 381 - 388 Title/Abstract Full Text View citing articles Show Details


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Assay Description

Effect : |DNA; examination of Target : calf thymus DNA Bioassay : sodium salt of DNA, average molecular weight 1E6; Tris-HCl pH 7.5; room temp; various incubation time (up to 5 h); effect on breakage of calf thymus DNA; DNA hydrolyse; kinetic

Results

ca. 45 percent DNA was degraded after 5 h at 0.4 mM; dose- and time-respone relationships

Citation

Khan, Nelofer S.; Hadi

Mutagenesis, 1998 , vol. 13, # 3 p. 271 - 274 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |DNA; examination of Target : supercoiled plasmid pBr322 DNA Bioassay : Tris-HCl pH 7.5; room temp; incubation time: 1 h; agarose gel electrophoresis assay; DNA cleavage assay

Results

title comp. was capable of DNA cleavage resulting in linear molecules with smaller sized fragments

Citation

Khan, Nelofer S.; Hadi

Mutagenesis, 1998 , vol. 13, # 3 p. 271 - 274 Title/Abstract Full Text View citing articles Show Details

Results

in vitro trypanocidal activity against Trypanosoma brucei brucei (GUTat 3.1): on bloodstream forms: GI50=15.60 μM, TGI=31.28 μM, LD50=46.96 μM, and on procyclic forms: GI50=14.44 μM, TGI=20.78 μM, LD50=30.02 μM

Citation

Koide, Tatsuo; Nose, Mitsuhiko; Inoue, Makoto; Ogihara, Yukio; Yabu, Yoshisada; Ohta, Nobuo

Planta Medica, 1998 , vol. 64, # 1 p. 27 - 30 Title/Abstract Full Text View citing articles Show Details

Results

inhibition of lipid oxidation in lecithin liposome in the absence (PC) or presence of bovine serum albumin (PC-BSA) at 5 μM: conjugated diene production = -34.6percent (PC) and -23.8percent (PC-BSA), hexanal production = -53.8percent (PC) and -248.5per

Citation

Heinonen, Marina; Rein, Dietrich; Satue-Gracia, M. Teresa; Huang, Shu-Wen; German, J. Bruce; Frankel, Edwin N.

Journal of Agricultural and Food Chemistry, 1998 , vol. 46, # 3 p. 917 - 922 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : in vitro; effect on 6β- and 16α-androstenedione hydroxylases assessed; 43.75 μmol/l androstenedione; assay buffer; 37 deg C; incubated for 10 min; liquid scintillation counting

Results

title comp. changed 6β-/16α-androstenedione hydroxylase activity from 0.66/1.06 to 0.43/0.60 nmol/mg/min

Citation

Stupans, Ieva; Kirlich, Amra; Tuck, Kellie L; Hayball, Peter J

Journal of agricultural and food chemistry, 2002 , vol. 50, # 8 p. 2464 - 2469 Title/Abstract Full Text Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : in vitro; effect on 6β-androstenedione hydroxylase assessed; 43.75 μmol/l androstenedione; assay buffer; 37 deg C; incubated for 10 min; liquid scintillation counting

Results

title comp. changed enzyme activity from 0.50 to 0.25 nmol/mg/min

Citation

Stupans, Ieva; Kirlich, Amra; Tuck, Kellie L; Hayball, Peter J

Journal of agricultural and food chemistry, 2002 , vol. 50, # 8 p. 2464 - 2469 Title/Abstract Full Text Show Details

Effect

Antioxidant

Assay Description

Target : Hooded Wistar rat liver microsomes


Bioassay : in vitro; effect on reactive oxygen species generation assessed; DCF-DA preincubated microsomes assay buffer, pH 7.4; 37 deg C; incubated for 25 min; reactive oxygen species generation monitored spectrofluorometrically

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Results

title comp. changed reactive oxygen species generation from 21 to 14.4 nmol of DCF/mg/h

Citation

Stupans, Ieva; Kirlich, Amra; Tuck, Kellie L; Hayball, Peter J

Journal of agricultural and food chemistry, 2002 , vol. 50, # 8 p. 2464 - 2469 Title/Abstract Full Text Show Details

Effect

Antioxidant

Assay Description

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Results

title comp. changed reactive oxygen species generation from 14.4 to 10.2 nmol of DCF/mg/h

Citation

Stupans, Ieva; Kirlich, Amra; Tuck, Kellie L; Hayball, Peter J

Journal of agricultural and food chemistry, 2002 , vol. 50, # 8 p. 2464 - 2469 Title/Abstract Full Text Show Details

Target

Tumor necrosis factor:Wild

Assay Description

Effect : TNF-α production; induction of Bioassay : incubation continued for 24 h; TNF-α level determined by ELISA in vitro; effect of title comp. on TNF-α production in LPS/INF-γ - activated cells; 6E5 cells well incubated with title comp. in DMEM with 10 percent FBS at 37 deg C for 1 h before stimulation with 10 ng/ml LPS and 10-50 U/ml IFN-γ

Results

TNF-α ( percent relative to LPS/IFN-γ alone) / dose (μmol/l): 122.0/16, 112.1/31, 117.4/63, 123.8/125, 130.6/250, 48.0/500

Citation

Wang, Jian; Mazza

Journal of agricultural and food chemistry, 2002 , vol. 50, # 15 p. 4183 - 4189 Title/Abstract Full Text Show Details

Biological material

CHO-K1 cell line

Assay Description

Effect : |sister chromatid exchange; examination of Bioassay : SOD: superoxide dismutase; CAT: catalase; SCE: sister-chromatid exchance 6E5 cells were seeded into plugged tissue-culture flasks; after 48 h title comp. with or without oxygen radical scavengers (SOD and CAT) was added; cells were treated for 3 h; then incubated for an additional 27 h in plugged flasks

Results

induction of SCEs at conc. >= 0.5 mM; SOD+CAT inhibited SCE induction at 1.5- 2 mM of title comp.; increase of SCE freq. at 1 mM and +SOD; 1 mM of title comp. added with CAT or CAT+SOD to the culture no longer caused a signif. increase in the SCE

Citation

Tayama, Sumiko; Nakagawa, Yoshio

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2001 , vol. 498, # 1-2 p. 117 - 127 Title/Abstract Full Text View citing articles Show Details

Effect

Antiproliferative

Biological material

CHO-K1 cell line

Assay Description

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Target : human liver microsomes Bioassay : in vitro; effect on reactive oxygen species generation assessed; DCF-DA preincubated microsomes assay buffer, pH 7.4; 37 deg C; incubated for 25 min; reactive oxygen species generation monitored spectrofluorometrically

Bioassay : AT: 3-amino-1,2,4-triazole 6E5 cells were seeded into plugged tissue-culture flasks; after 48 h title comp. with inhibitor of catalase activity (AT) was added; cells were treated for 3 h; then incubated for an additional 27 h in plugged flasks

Results

no proliferating cells were observed

Citation

Tayama, Sumiko; Nakagawa, Yoshio

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2001 , vol. 498, # 1-2 p. 117 - 127 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic


Biological material Assay Description

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at conc. >= 0.5 mM no inducing of CAs; SOD+CAT improved cell-cycle delay (from 78 or 72 percent to 92 or 90 percent DSC) at 1.5 and 2 mM of title comp.

Citation

Tayama, Sumiko; Nakagawa, Yoshio

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2001 , vol. 498, # 1-2 p. 117 - 127 Title/Abstract Full Text View citing articles Show Details

Effect

Cytostatic

Biological material

human WIL2 NS cell line

title comp. had no significant influence on nuclear division index of H2O2/tert-butylhydroperoxide treated cells; table

Citation

Sugisawa, Ayako; Kimura, Michiyo; Fenech, Michael; Umegaki, Keizo

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 559, # 1-2 p. 97 - 103 Title/Abstract Full Text View citing articles Show Details

Effect

Cytostatic

Biological material

human WIL2 NS cell line

Bioassay : control: untreated cells; positive controls: H2O2, tert-butylhydroperoxide; cells isolated from spleen of Caucasian male with hereditary spherocytic anemia was used cell suspensions incubated with title comp. for 60 min; resuspended in RPMI 1640 medium; after 42 h of culture, cells harvested; nuclear division index determined by CBMN assay

Citation

Sugisawa, Ayako; Kimura, Michiyo; Fenech, Michael; Umegaki, Keizo

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 559, # 1-2 p. 97 - 103 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic

Biological material

human WIL2 NS cell line

Assay Description

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Bioassay : control: untreated cells; cells isolated from spleen of Caucasian male with hereditary spherocytic anemia was used cell suspensions incubated with title comp. for 60 min at 37 deg C; exposed to H2O2/tert-butylhydroperoxide at for 30 min; resuspended in RPMI 1640 medium; after 42 h of culture, cells harvested; nuclear division index determined by CBMN assay

Results

Assay Description

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Bioassay : SOD: superoxide dismutase; CAT: catalase; CA: chromosome aberration; ERDs: endoreduplications; DSC: cell-cycle delay 6E5 cells were seeded into plugged tissue-culture flasks; after 48 h title comp. with or without oxygen radical scavengers (SOD and CAT) was added; cells were treated for 3 h; then incubated for an additional 27 h in plugged flasks

Results

Assay Description

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CHO-K1 cell line

Bioassay : control: untreated cells; t-BuOOH: tert-butylhydroperoxide; chromosomal damage: number of micronucleated binucleate cells/1000 binucleated cells; cells isolated from spleen of Caucasian male with hereditary spherocytic anemia was used cell suspensions incub. with title comp. for 60 min at 37 deg C; exposed to H2O2/t-BuOOH for 30 min; resuspended in RPMI 1640 medium; after 42 h of culture, cells harvested; chromosomal damage assessed by CBMN assay

Results

title comp. even at 1 μmol/l prevented the H2O2-induced chromosomal damage; title comp. did not prevent inhibition of t-BuOOH-induced chromosomal damage, even at 10 μmol/l; diagram, table

Citation

Sugisawa, Ayako; Kimura, Michiyo; Fenech, Michael; Umegaki, Keizo

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 559, # 1-2 p. 97 - 103 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic

Biological material

human WIL2 NS cell line

Assay Description

Bioassay : control: untreated cells; positive controls: H2O2, tert-butylhydroperoxide; chromosomal damage: number of micronucleated binucleate cells/1000 binucleated cells; cells isolated from spleen of Caucasian male with hereditary spherocytic anemia was used cell suspensions incubated with title comp. for 60 min; resuspended in RPMI 1640 medium; after 42 h of culture, cells harvested; chromosomal damage assessed by CBMN assay


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Citation

Sugisawa, Ayako; Kimura, Michiyo; Fenech, Michael; Umegaki, Keizo

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 559, # 1-2 p. 97 - 103 Title/Abstract Full Text View citing articles Show Details

Effect

Antineoplastic

Biological material

human T-47D cell line

Assay Description

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Bioassay : HIF-1: hypoxia-inducible factor-1 in vitro; effect of title comp. on HIF-1 activity monitored using a luciferase reporter under the control of HRE from the erythropoietin gene (pTK-HRE3-luc); DMEM/F12 medium; incubated for 16 h at 37 deg C under normoxic and hypoxic conditions (1% O2)

Citation

Zhou, Yu-Dong; Kim, Yong-Pil; Li, Xing-Cong; Baerson, Scott R.; Agarwal, Ameeta K.; Hodges, Tyler W.; Ferreira, Daneel; Nagle, Dale G.

Journal of Natural Products, 2004 , vol. 67, # 12 p. 2063 - 2069 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : cell membrane; binding affinity Target : Caco-2 cell membranes Bioassay : BSA: bovine serum albumin; DPBS: Dulbecco's phosphate buffered saline; SHP: streptavidin-horseradish peroxidase; IC50 is concentration at which 50 percent inhibition of UEA1 binding occurred cell membranes coated onto microtiter plates overnight, 4 deg C; blocked with BSA in DPBS, room temp.; washed, added BSA-DPBS, biotin-labeled UEA1 and title comp., incubated overnight, 4 deg C; detected bound UEA1 using SHP and o-phenylenediamine by UV

Citation

Hamashin, Christa; Spindler, Lisa; Russell, Shannon; Schink, Amy; Lambkin, Imelda; O'Mahony, Daniel; Houghten, Richard; Pinilla, Clemencia

Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 23 p. 4991 - 4997 Title/Abstract Full Text View citing articles Show Details

Biological material

3T3-L1 cell line

Assay Description

Effect : GLUT4 translocation Target : myc-GLUT4-GFP chimera 70 % confluency cell culture tested; incubation time with title comp.: 30 min; GLUT4: glucose transporter 4

Results

maximal percentage increase 90 %

Citation

Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar

FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details

Biological material

3T3-L1 cell line

Assay Description

Effect : phosphorylation Target : ;AMPK differentiated cells tested; incubation time with title comp.: 30 min; AMPK: AMP-activated protein kinase

Citation

Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar

FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details

Biological material

3T3-L1 cell line

Assay Description

Effect : phosphorylation Target : ;Akt differentiated cells tested; incubation time with title comp.: 30 min; AMPK: AMP-activated protein kinase

Citation

Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar

FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details

Biological material

3T3-L1 cell line

Assay Description

Effect : phosphorylation


Target : ;aPKCζ/λ differentiated cells tested; incubation time with title comp.: 30 min; aPKCζ/λ: atypical protein kinase Cζ/λ

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Results

fold increase 1.4

Citation

Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar

FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |enzyme; inhibition of Bioassay : effect on enzyme activity evaluated using spectrophotometric method; linoleic acid used as enzyme substrate; assay buffer, pH 8.0; 25 deg C; formation of product, 13S-linoleic acid hydroperoxide, monitored continuously at 234 nm

Citation

Ha, Tae Joung; Nihei, Ken-Ichi; Kubo, Isao

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 10 p. 3177 - 3181 Title/Abstract Full Text View citing articles Show Details

Effect

Antiadhesive

Assay Description

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Target : type O erythrocytes Bioassay : ICAM 1: intercellular adhesion molecule 1; IE: infected erythrocytes; PS prepd. by culturing Plasmodium falciparum ITO4-A4 in type O erythrocytes in RPMI 1640 medium; control: DMSO microslides coated for 72 h at 37 deg C with human ICAM 1-Fc; blocked overnight (4 deg C); title comp. added to parasite suspension (PS); after 20 min, PS allowed to flow through microslides (5 min); stationary IE counted; IE rolling velocity analyzed

Results

title comp. had no major effect on adhesion; diagram

Citation

Dormeyer, Matthias; Adams, Yvonne; Kramer, Bernd; Chakravorty, Srabasti; Tse, Man Tsuey; Pegoraro, Stefano; Whittaker, Lisa; Lanzer, Michael; Craig, Alister

Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 2 p. 724 - 730 Title/Abstract Full Text View citing articles Show Details

Biological material

Mus musculus 3T3-L1 cell line

Assay Description

Effect : cell number cells harvested 8 days after initiation of differentiation

Citation

Hsu, Chin-Lin; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 21 p. 8404 - 8410 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : free radical scavenging Target : linoleic acid peroxyl radical Bioassay : linoleic acid peroxyl radical test carried out in micelle system prepared using rac-1-lauroylglycerol and deoxycholic acid sodium salt

Results

1/IC50 reciprocal of inhibitory concentration 1.24 l/μmol

Citation

Rossetto, Monica; Vanzani, Paola; De Marco, Veronica; Zennaro, Lucio; Scarpa, Marina; Rigo, Adelio

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 10 p. 3486 - 3492 Title/Abstract Full Text View citing articles Show Details

Effect

Antiviral

Assay Description

Effect : virucidal Species : P22 bacteriophage host bacteria for title comp.-treated species: Salmonella typhimurium

Citation

Giao, Maria S.; Borges, Andre B.; Guedes, Catarina J.; Hogg, Tim A.; Pintado, Manuela E.; Malcata, F. Xavier

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 1 p. 22 - 25 Title/Abstract Full Text View citing articles Show Details


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Effect

Antibiotic

Biological material

Listeria monocytogenes

Assay Description

Effect : antilisterial Species : Listeria monocytogenes Scott A conductance method

Results

detection time 9.5 - 14.9 h

Citation

Anastasiadi, Maria; Chorianopoulos, Nikos G.; Nychas, George-John E.; Karoutounian, Serkos A.

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 2 p. 457 - 463 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Biological material

Listeria monocytogenes

Assay Description

Effect : antilisterial Species : Listeria monocytogenes Scott A count technique

Results

final viable count <1-8.75 log(CFU/ml)

Citation

Anastasiadi, Maria; Chorianopoulos, Nikos G.; Nychas, George-John E.; Karoutounian, Serkos A.

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 2 p. 457 - 463 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : radical scavenging Bioassay : 1,1'-diphenyl-2-picrylhydrazyl

Results

SC50 scavenging concentration 15.4 μmol/l

Citation

Liu, Qing; Zhang, Ying-Tun; Yang, Chong-Ren; Xu, Mei

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 2 p. 586 - 590 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : 2,2-azobis(2-amidinopropane hydrochloride) TE: Trolox equivalents; test system as a solution used

Results

ORACFL oxygen radical absorbance capacity 8.22 μmol TE/ml

Citation

Alamed, Jean; Chaiyasit, Wilailuk; McClements, D. Julian; Decker, Eric A.

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2969 - 2976 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : protein expression Target : ;catalase Bioassay : colorectal adenoma LT97 cells

Citation

Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details


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Biological material

human

Assay Description

Effect : protein expression Target : ;superoxide dismutase Bioassay : colorectal adenoma LT97 cells

Citation

Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : DNA damage Bioassay : colorectal adenoma LT97 cells

Citation

Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : enzyme activity Target : ;catalase Bioassay : colorectal adenoma LT97 cells

Citation

Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : enzyme activity Target : ;superoxide dismutase Bioassay : colorectal adenoma LT97 cells

Citation

Klenow, Stefanie; Jahns, Franziska; Pool-Zobel, Beatrice L.; Glei, Michael

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 7 p. 2999 - 3004 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human

Assay Description

Effect : LDH release Target : HPV Bioassay : prostate epithelial PZ-7 cells

Citation

Chen, Kuan-Chou; Hsieh, Chiu-Lan; Huang, Kuan-Dar; Ker, Yaw-Bee; Chyau, Charng-Cherng; Peng, Robert Y.

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 14 p. 6114 - 6122 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human NCI-H460 cell line

Assay Description

Effect : cell cycle PDP value is concentration-dependent

Results

percent cells in G2-M phase 26.98 - 36.06 %


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Citation

Bin-Chuan; Hsu, Wu-Huei; Yang, Jai-Sing; Hsia, Te-Chun; Lu, Chi-Cheng; Chiang, Jo-Hua; Yang, Jiun-Long; Lin, Ching-Hsiung; Jen-jyh; Lee-jen, Wu Suen; Wellington, Gibson Wood; Chung, Jing-Gung

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 16 p. 7596 - 7604 Title/Abstract Full Text View citing articles Show Details

Effect

Cardioprotective

Biological material

Rattus norvegicus

Assay Description

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Results

title comp. significantly improved contractile function during reperfusion

Citation

Yamashiro, Satoshi; Noguchi, Katsuhiko; Matsuzaki, Toshihiro; Miyagi, Kanako; Nakasone, Junko; Sakanashi, Mayuko; Sakanashi, Makiko; Kukita, Ichiro; Aniya, Yoko; Sakanashi, Matao

Pharmacology, 2003 , vol. 67, # 3 p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

Target

cytokine:Wild

Assay Description

Effect : cytokine production; inhibition of Bioassay : MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; control: without title comp. and without DSS (IL-1β level 1.37 pg/ml), without title comp. (IL-1β level 103 pg/ml); DSS: dextran sulfate sodium test cells incubated with title comp. in Dulbecco's Modified Eagle Medium at 37 deg C for 30 min in 5 percent humidified CO2 atmosphere; 1 μg/ml DSS added and incubated for 12 h; IL-1β level in medium supernatant measured with ELISA

Results

title comp. caused decrease of IL-1β level to 91.7 and 36.4 pg/ml at 20 and 100 μmol/l, respectively

Citation

Kwon, Ki Han; Murakami, Akira; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 2 p. 436 - 439 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : radical scavenging activity Bioassay : DPPH radical DPPH:1,1-diphenyl-2-picrylhydrazyl; SC50: concentration necessary for 50% reduction of DPPH radical

Results

SC50 13.5 μmol/l

Citation

Gao, Da-Fang; Xu, Min; Yang, Chong-Ren; Xu, Mei; Zhang, Ying-Jun

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 15 p. 8820 - 8824 Title/Abstract Full Text View citing articles Show Details

Effect

Mitogenic

Assay Description

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Bioassay : metabolic changes further studied isolated hearts subjected to 30 min global ischemia at 37 deg C followed by 20-min reperfusion; left ventricular function studied

Target : BAF/IL10R cells Bioassay : cell proliferation activity evaluated; 1E5 cells/well; humidified 5 percent CO2 in air; 37 deg C; incubated for 24 h; cell proliferation measured by colorimetric 2-(4-iodophenyl)-3-(4nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium-based assay

Results

title comp. showed conc.-dependent IL-10-like proliferation activity with max. at 30 μg/ml

Citation

Nishimura, Tadahiro; Wang, Li-Yan; Kusano, Kouji; Kitanaka, Susumu

Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 3 p. 305 - 308 Title/Abstract Full Text View citing articles Show Details

Effect

Mitogenic

Assay Description

Target : BAF/InsR cells Bioassay : cell proliferation activity evaluated; 1E5 cells/well; humidified 5 percent CO2 in air; 37 deg C; incubated for 24 h; cell proliferation measured by colorimetric 2-(4-iodophenyl)-3-(4-


nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium-based assay

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Citation

Nishimura, Tadahiro; Wang, Li-Yan; Kusano, Kouji; Kitanaka, Susumu

Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 3 p. 305 - 308 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Biological material

human Hep G2

Assay Description

Effect : |enzyme; induction of Bioassay : DMEM with 10 percent FBS; humidified atmosphere of 95 percent air and 5 percent CO2; 37 deg C; incubated for 24 h; induction of P-form phenolsulfotransferase activity assayed

Results

title comp. induced enzyme activity in conc.-dependent manner with maximum of 4-5-fold induction

Citation

Yeh, Chi-Tai; Huang, Shang-Ming; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 12 p. 4766 - 4773 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Biological material

human Hep G2

Assay Description

Effect : |enzyme; induction of Bioassay : DMEM with 10 percent FBS; humidified atmosphere of 95 percent air and 5 percent CO2; 37 deg C; incubated for 3-24 h; induction of P-form phenolsulfotransferase (PST-P) mRNA expression and protein translation determined by RT-PCR and Western blot analysis, respectively

Results

title comp. induced P-PST mRNA expression and protein translation in conc.- and time-dependent manner

Citation

Yeh, Chi-Tai; Huang, Shang-Ming; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 12 p. 4766 - 4773 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human Hep G2

Assay Description

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Results

at 50 μmol/l title comp. inhibited cell growth by 6 percent

Citation

Yeh, Chi-Tai; Huang, Shang-Ming; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 12 p. 4766 - 4773 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human Hep G2

Assay Description

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Bioassay : DMEM with 10 percent FBS; humidified atmosphere of 95 percent air and 5 percent CO2; 37 deg C; incubated for 24 h; cell viability determined with 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide colorimetric assay

Bioassay : DMEM with 10 percent FBS; humidified atmosphere of 95 percent air and 5 percent CO2; 37 deg C; incubated for 24 h; cell viability determined with lactate dehydrogenase assay

Citation

Yeh, Chi-Tai; Huang, Shang-Ming; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 12 p. 4766 - 4773 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild


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Biological material

Rattus norvegicus

Assay Description

Effect : |enzyme; inhib. of Bioassay : sodium azide (250 μmol/l) as reference completely inhibited enzyme activity myeloperoxidase studied; title comp. used in reaction medium with 50 mmol/l NaH2PO4, 0.167 mg/ml τ-dianisidine and 0.0005 percent H2O2 at 25 deg C; enzyme activity measured spectrophotometrically at 450 nm; control without title comp.

Results

K0.5 28.7 μmol/l

Citation

Rosso, Rober; Vieira, Tiago O.; Leal, Paulo C.; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.

Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 18 p. 6409 - 6413 Title/Abstract Full Text View citing articles Show Details

Effect

Hepatotoxic

Biological material

Rattus norvegicus

Assay Description

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Bioassay : liver slices incubated with title comp. for 1 h at 37 deg C in HEPES; cell viability determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide-formazan assay; optical density measured at 550 nm; control without title comp.

Citation

Rosso, Rober; Vieira, Tiago O.; Leal, Paulo C.; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.

Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 18 p. 6409 - 6413 Title/Abstract Full Text View citing articles Show Details

Effect

Antihistaminic

Biological material

Rattus norvegicus mast cell

Assay Description

Effect : 48/80 compound - induced histamine release

Citation

Bao, Li; Yao, Xinsheng; Xu, Jiekun; Guo, Xiaoyu; Liu, Hongwei; Kurihara, Hiroshi

Fitoterapia, 2009 , vol. 80, # 6 p. 349 - 353 Title/Abstract Full Text View citing articles Show Details

Target

P-selectin [human]:Wild

Assay Description

Effect : E-selectin binding; inhibition of Bioassay : Competition assay of gallic acid (derivatives) and polyphenols with PAA-Lea-SO3H To be able to test gallic acid binding also to other members of the selectin family (i.e. E- and L-selectin), biotin-PAA-Lea-SO3H (Synthesone, Munich, Germany) instead of TM11-PO was used as ligand in the competition

Citation

YAMANOUCHI PHARMACEUTICAL CO. LTD.

Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details

Biological material

human HL-60 cell line

Assay Description

Effect : cell interaction; inhibition of Bioassay : Inhibition of dynamic interactions between HL60 cells and human P-selectin expressing Chinese hamster ovary cells Chinese hamster ovary (CHO) cells stably transfected with human P-selectin (CHO-P) were kindly donated by Dr. Modderman (University of Amsterdam, Amsterdam, the Netherlands). Cells

Results

significantly decreased HL60 cell adhesion to the CHO-P monolayer at 50 µM irrespective of the wall shear rates; at 250 µM, the effect was even more pronounced (-41 % and -54% respectively); The rolling velocity of the HL60 cells rolling

Citation

YAMANOUCHI PHARMACEUTICAL CO. LTD.

Patent: EP1481669 A1, 2004 ; Title/Abstract Full Text Show Details

Assay Description

Effect : |drug interaction Target : phreochromocytoma PC12 cells of rat Bioassay : Materials and Methods Dexamethasone, L-glutamate and all test agents were obtained from Sigma (except Pycnogenol which was obtained from Nature's Aid, Preston, UK) and initially dissolved in ETOH to make 10 mM stock solutions. These were then used to prepare experimental concentrations. 1: 1000


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Results

title comp. and quercetin induced dose-dependent synergistic reduction of prostaglandin E2 and leukotriene B4 levels

Citation

UNILEVER PLC; UNILEVER NV; HINDUSTAN LEVER LIMITED

Patent: WO2005/67915 A1, 2005 ; Title/Abstract Full Text Show Details

Biological material

Lemna paucicostata

Assay Description

Effect : plant growth; inhibition of Bioassay : Example 4 Evaluation on the Efficacy of Natural Compounds In order to investigate the growth inhibiting activity to Marchantia polymorpha L. photomixotrophic cells of natural compounds isolated from various plants (Table 3), the present inventors performed the efficacy evaluation test used in the above

Citation

Korea Research Institute of Bioscience and Biotechnology

Patent: US2005/176584 A1, 2005 ; Title/Abstract Full Text Show Details

Effect

Antiproliferative

Assay Description

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Results

title compound provides inhibition activity 8 % at 1 ppm

Citation

Korea Research Institute of Bioscience and Biotechnology

Patent: US2005/176584 A1, 2005 ; Title/Abstract Full Text Show Details

Results

inhibitory activity against Staphylococcus aureus NCTC6571, Pseudomonas aeruginosa NCTC6750, Escherichia coli NCTC8545, and Bacillus subtilis NCTC7801

Citation

Richards; Durham; Liu

Planta Medica, 1994 , vol. 60, # 5 p. 471 - 473 Title/Abstract Full Text View citing articles Show Details

Results

moderate mutagenicity on Salmonella typhimurium TA 100

Citation

Yamaguchi, Tsutomu

Agricultural and Biological Chemistry, 1981 , vol. 45, # 1 p. 327 - 330 Title/Abstract Full Text Show Details

Effect

Antioxidant

Biological material

human fibroblast

Assay Description

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Target : photomixotrophic cells of Marchantia polymorpha L. Bioassay : Example 4 Evaluation on the Efficacy of Natural Compounds In order to investigate the growth inhibiting activity to Marchantia polymorpha L. photomixotrophic cells of natural compounds isolated from various plants (Table 3), the present inventors performed the efficacy evaluation test used in the above

Bioassay : survival analysis (survival as percentage for survival of the control cells) cell cultivation for 1 d; exposure to 1 mM H2O2 for 2 h in the presence of title comp.; neutral red method

Results

title comp. strongly inhibited H2O2-induced cell damage (table given)

Citation

Masaki, Hitoshi; Okamoto, Nobuo; Sakaki, Sachiko; Sakurai, Hiromu

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 304 - 308 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

human fibroblast

Assay Description

Bioassay : survival analysis (survival as percentage for survival of the control cells) cell cultivation for 1 d; title comp. treatment for 24 h; washing with Hanks balanced salt solution; exposure to 1 mM


H2O2 for 2 h; neutral red method

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Citation

Masaki, Hitoshi; Okamoto, Nobuo; Sakaki, Sachiko; Sakurai, Hiromu

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 304 - 308 Title/Abstract Full Text View citing articles Show Details

Results

no acetyl-CoA carboxylase inhibitory activity

Citation

Watanabe; Kawabata; Niki

Bioscience, biotechnology, and biochemistry, 1998 , vol. 62, # 3 p. 532 - 534 Title/Abstract Full Text View citing articles Show Details

Results

weakly active according to NCCLS recommendations (MIC: <μg/ml>) against Candida albicans ATCC 14053 (500), Cryptococcus neoformans KF-33 (250), Saccharomyces cerevisiae PLM 454 (1000)

Citation

Sardari; Able; Micetich; Daneshtalab

Pharmazie, 1999 , vol. 54, # 2 p. 156 - 158 Title/Abstract Full Text View citing articles Show Details

Results

affinity for lipid bilayers evaluated with egg PC liposome system

Citation

Nakayama; Ono; Hashimoto

Bioscience, biotechnology, and biochemistry, 1998 , vol. 62, # 5 p. 1005 - 1007 Title/Abstract Full Text Show Details

Results

inhibitory activity against rat lens aldose reductase (AR) IC50 >100 μM

Citation

Terashima; Shimizu; Horie; Morita

Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 12 p. 3346 - 3347 Title/Abstract Full Text View citing articles Show Details

Biological material

human smooth muscle cell

Assay Description

Effect : cholesterol efflux; stimulatory effect on Bioassay : Figure 10 is a graph showing the effect of active compounds from EO on efflux of cholesterol in human aortic smooth muscle cells. Confluent culture of H- ASMC in 96 well plates was incubated with [3H] cholesterol (5 μCi/ml) for 24 h. Medium was replaced with fresh medium and incubation with herbal

Results

title compound significantly induced efflux of cholesterol from cells; figure is given

Citation

THE JOHNS HOPKINS UNIVERSITY; MERLION PHARMACEUTICAL PTC LTD

Patent: WO2008/80162 A2, 2008 ; Title/Abstract Full Text Show Details

Biological material

human smooth muscle cell

Assay Description

Effect : cholesterol uptake; inhibition of Bioassay : Figure 11 is a graph showing the effect of active compounds from EO on uptake of cholesterol in human aortic smooth muscle cells. Confluent culture of cells grown in 96 well plates was incubated in serum- free medium with [3H] cholesterol (5 μCi/ml) with and without active fractions. After 24 h the

Results

title compound markedly inhibited cholesterol uptake in cells; figure is given

Citation

THE JOHNS HOPKINS UNIVERSITY; MERLION PHARMACEUTICAL PTC LTD

Patent: WO2008/80162 A2, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Bioassay : samples collected; activated carbon (PACV) equilibrated with title comp.; UV-visible spectrophotometer at 212 nm, at 27 deg C; adsorption isotherm fitted to Freundlich, Langmuir and DubininRadushkevich equations


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Results

adsorption Freundlich constant (KF): 0.32 mg/g; table; figure

Citation

Figaro; Louisy-Louis; Lambert; Ehrhardt; Ouensanga; Gaspard

Water Research, 2006 , vol. 40, # 18 p. 3456 - 3466 Title/Abstract Full Text View citing articles Show Details

Assay Description

Results

adsorption Freundlich constant (KF): 51.35 mg/g; Langmuir constant (KL): 0.030 l/mg; maximum adsorption of title comp. in micropore (QDR): 598 mg/g; table; figure

Citation

Figaro; Louisy-Louis; Lambert; Ehrhardt; Ouensanga; Gaspard

Water Research, 2006 , vol. 40, # 18 p. 3456 - 3466 Title/Abstract Full Text View citing articles Show Details

Assay Description

adsorption Freundlich constant (KF): 76.0 mg/g; Langmuir constant (KL): 0.08 l/mg; maximum adsorption of title comp. in micropore (QDR): 515 mg/g; table; figure

Citation

Figaro; Louisy-Louis; Lambert; Ehrhardt; Ouensanga; Gaspard

Water Research, 2006 , vol. 40, # 18 p. 3456 - 3466 Title/Abstract Full Text View citing articles Show Details

Effect

Inotropic : Negative

Target : guinea pig atria Bioassay : left and right atria mounted separately in tissue bath (Krebs' solution, 32 deg C), left atria stimulated with rectangular pulses; after equilibration period, title comp. added; tension changes recorded via a Grass force-displacement transducer

Citation

Ghayur; Gilani, Anwarul Hassan

Pharmazie, 2007 , vol. 62, # 1 p. 67 - 71 Title/Abstract Full Text View citing articles Show Details

Effect

Spasmogenic

Biological material

rabbit

Assay Description

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Bioassay : samples collected; activated carbon (PAC6) equilibrated with title comp.; UV-visible spectrophotometer at 212 nm, at 27 deg C; adsorption isotherm fitted to Freundlich, Langmuir and DubininRadushkevich equations

Results

Assay Description

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Bioassay : samples collected; activated carbon (PAC5) equilibrated with title comp.; UV-visible spectrophotometer at 212 nm, at 27 deg C; adsorption isotherm fitted to Freundlich, Langmuir and DubininRadushkevich equations

Bioassay : jejunum mounted in tissue bath (Tyrode's solution, 37 deg C), preload of 1 g applied; after equilibration period (30 min), title comp. added; tension changes in tissue recorded via a Grass forcedisplacement transducer

Citation

Ghayur; Gilani, Anwarul Hassan

Pharmazie, 2007 , vol. 62, # 1 p. 67 - 71 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : antibiotic resistance; effect on Target : Staphylococcus aureus OM584 Bioassay : OM584 strain: methicillin-resistant clinical isolate from Okayama University Hospital; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined

Results

title comp. decreased oxacillin MIC from 256 to 32 μg/ml

Citation

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details


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Assay Description

Effect : antibiotic resistance; inhibition of Target : Staphylococcus aureus OM481 Bioassay : OM481 strain: methicillin-resistant clinical isolate from Okayama University Hospital; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined

Results

title comp. decreased MIC of oxacillin from 256 to 2 μg/ml

Citation

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : antibiotic resistance; inhibition of Target : Staphylococcus aureus OM505 Bioassay : OM505 strain: methicillin-resistant clinical isolate from Okayama University Hospital; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined

Results

title comp. decreased oxacillin MIC from 64 to 32 μg/ml

Citation

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : antibiotic resistance; inhibition of Target : Staphylococcus aureus OM623 Bioassay : OM623 strain: methicillin-resistant clinical isolate from Okayama University Hospital; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined

Results

in presence of title comp. oxacillin MIC decreased from 256 to 64 μg/ml

Citation

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : antibiotic resistance; effect on Target : Staphylococcus aureus 209P Bioassay : 209P strain: methicillin-sensitive; MIC: the lowest conc. at wich bacterial culture lacked visual turbidity after incubation liquid dilution assay in cation-supplemented Mueller-Hinton broth; incubation with title comp. and oxacillin at 32 deg C for 24 h; MIC of oxacillin determined

Citation

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |protein binding Target : B14 Chinese hamster fibroblast cells Bioassay : control cells treated with phosphate buffer saline (pH 7.4) or Cu(2+) or H2O2; two replicates cells incubated with title comp. with/without Cu(2+) (50μmol/l) or H2O2 (10 μmol/l) for 1 h at 5 deg C; carbonyl groups assayed by method based on use of 2,4-dinitrophenylhydrazine (dissolved in 2M HCl) by spectrophotometricaly (at 370 nm)

Results

title comp. significantly increased carbonyl groups in cells in dose-dependent manner; presence of Cu(2+) or H2O2 intensify effect of title comp. and increased carbonyl groups in cells (histograms)

Citation

Labieniec, Magdalena; Gabryelak, Teresa

Toxicology Letters, 2005 , vol. 155, # 1 p. 15 - 25 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

Target : B14 Chinese hamster fibroblast cells Bioassay : control cells treated with phosphate buffer saline with pH 7.4 (PBS) Trypan blue exclusion assay: cells incubated with title comp. for 1-24 h at 5 deg C; then cells rinsed in PBS and resuspended in 0.4 percent Trypan blue dye; cell viability calculated as percent ratio of referent control

Results

title comp. caused reduction in viability of digestive gland cells in conc.-dependent manner but cell viability was >70 percent (table)

Citation

Labieniec, Magdalena; Gabryelak, Teresa

Toxicology Letters, 2005 , vol. 155, # 1 p. 15 - 25


Title/Abstract Full Text View citing articles Show Details

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Effect Assay Description

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title comp. demonstrated genotoxic effect and contribute to DNA damage at 15 and 60 μmol/l, at 1 μmol/l title comp. did not caused strand breaks in DNA; Cu(2+) or H2O2 intensify effect of title comp. exclude at 60 μmol/l with H2O2 (histograms)

Citation

Labieniec, Magdalena; Gabryelak, Teresa

Toxicology Letters, 2005 , vol. 155, # 1 p. 15 - 25 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

Oncorhynchus mykiss erythrocyte

title comp. exerted protective effect at 1 and 5 μmol/l; diagram

Citation

Fedeli, Donatella; Berrettini, Marco; Gabryelak, Teresa; Falcioni, Giancarlo

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 563, # 2 p. 89 - 96 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

Oncorhynchus mykiss erythrocyte

Bioassay : RBCs: red blood cells RBCs suspended (2E6 RBCs/ml); CO-saturated erythrocytes or cells exposed to air incubated with title comp. at 35 deg C, pH 6.3; t1/2 of hemolysis determined spectrophotometrically at 540 nm

Citation

Fedeli, Donatella; Berrettini, Marco; Gabryelak, Teresa; Falcioni, Giancarlo

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 563, # 2 p. 89 - 96 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic

Biological material

Oncorhynchus mykiss erythrocyte

Assay Description

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Bioassay : tail moment: index of DNA damage; considers extent of DNA migration in comet tail and fluorescence intensity of genetic material migrated out from comet head in comet tail cells (1E6 cells/ml) incubated with title comp. for 1 h at pH 6.3 and 35 deg C (oxidative stress conditions); cells embedded in agarose, followed by lysis, electrophoresis and staining (comet assay); fluorescence microscopy; tail moment determined

Results

Assay Description

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Target : B14 Chinese hamster fibroblast cells Bioassay : control cells treated with phosphate buffer saline (pH 7.4) or Cu(2+) or H2O2 cells incubated with title comp. with/without Cu(2+) (50μmol/l) or H2O2 (40 μmol/l) for 1 h at 5 deg C; cells fixed on 0.5 percent normal melting-point agarose and lysed; comet tail moment determined by single-cell gel electrophoresis (comet assay)

Results

Assay Description

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Genotoxic

Bioassay : reference: H2O2 (5 μmol/l); tail moment: index of DNA damage; considers extent of DNA migration in comet tail and fluorescence intensity of genetic material migrated out from comet head in comet tail erythrocytes incubated with title comp. for 1 h at pH 7.8 and 4 deg C; cells embedded in agarose, followed by lysis, electrophoresis and staining (comet assay); fluorescence microscopy; tail moment determined

Results

presence of 10 μmol/l of title comp. increased DNA damage to same extent as H2O2; diagram

Citation

Fedeli, Donatella; Berrettini, Marco; Gabryelak, Teresa; Falcioni, Giancarlo

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2004 , vol. 563, # 2 p. 89 - 96 Title/Abstract Full Text View citing articles Show Details

Effect

Proliferative

Assay Description


Target : Sea/ddy mouse hair epithelial cells Bioassay : proliferation quantified using <3H>thymidine incorporation method (24 h incubation, 37 deg C, 5 percent CO2); liquid scintillation counting; minoxidil (70 μg/ml, 140 percent of control) used as reference compound in vitro; cell suspension plated on collagen-coated plates and incubated in DMEM with 5 percent FBS at 37 deg C under 5 percent CO2 atmosphere for 24 h; cells washed with PBS and incubated with title comp. in MCDB153 for 4 h

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Results

title comp. stimulated proliferation of epithelial cells only at 1 and 10 μmol/l doses giving ca. 135 percent and ca. 150 percent of control, respectively

Citation

Towatari, Keisuke; Yoshida, Kiyo; Mori, Nobuhiro; Shimizu, Kuniyoshi; Kondo, Ryuichiro; Sakai, Kokki

Planta Medica, 2002 , vol. 68, # 11 p. 995 - 998 Title/Abstract Full Text View citing articles Show Details

Effect

Proliferative

Assay Description

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Results

title comp. stimulated cell proliferation reaching ca. 135 percent of control in MTT assay and ca. 145 percent according to cell count

Citation

Towatari, Keisuke; Yoshida, Kiyo; Mori, Nobuhiro; Shimizu, Kuniyoshi; Kondo, Ryuichiro; Sakai, Kokki

Planta Medica, 2002 , vol. 68, # 11 p. 995 - 998 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; induction of Bioassay : MGST: microsomal glutathione S-transferase; CDNB: 1-chloro-2,4-dinitrobenzene; GSH: reduced glutathione; further investigation in the presence of SOD (superoxide dismutase), catalase, reducing agents, redial scavengers microsomes incubated with title comp. in phosphate buffer (pH 7.4) at 30 deg C for 5 min; MGST1 activity measured using CDNB and GSH as substrates

Results

title comp. dose-dependently increased MGST1 activity acting through oxidative modification of enzyme (diagram)

Citation

Shinno, Etsuki; Shimoji, Miyuki; Imaizumi, Naoki; Kinoshita, Shizuka; Sunakawa, Hajime; Aniya, Yoko

Life Sciences, 2005 , vol. 78, # 1 p. 99 - 106 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; induction of Bioassay : MGST: microsomal glutathione S-transferase; GSH: reduced glutathione; CDNB: 1-chloro-2,4-dinitrobenzene GSH-free purified MGST1 incubated with title comp. in phosphate buffer (pH 7.4) at 30 deg C for 5 min; MGST1 activity measured using CDNB and GSH as substrates

Results

title comp. dose-dependently increased MGST1 activity (850 percent of control at 0.5 mmol/l) (diagram)

Citation

Shinno, Etsuki; Shimoji, Miyuki; Imaizumi, Naoki; Kinoshita, Shizuka; Sunakawa, Hajime; Aniya, Yoko

Life Sciences, 2005 , vol. 78, # 1 p. 99 - 106 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

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Target : Sea/ddy mouse hair epithelial cells Bioassay : viability of cells determined at day 5 by MTT assay and at day 6 by cell count in vitro; cell suspension plated on collagen-coated plates and incubated in DMEM with 5 percent FBS at 37 deg C under 5 percent CO2 atmosphere for 24 h; cells washed with PBS and incubated with title comp. in MCDB153 for 5 or 6 d

Target : Sprague-Dawley rat liver microsomes Bioassay : CL: chemiluminescence microsomes incubated with title comp. in the presence of NADPH generating system in phosphate buffer (pH 7.4); CL counted for 5 min

Results

title comp. decreased CL production (diagram)

Citation

Shinno, Etsuki; Shimoji, Miyuki; Imaizumi, Naoki; Kinoshita, Shizuka; Sunakawa, Hajime; Aniya, Yoko

Life Sciences, 2005 , vol. 78, # 1 p. 99 - 106 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |biotransformation Target : Erwinia rhapontici SL-3


Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography

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Citation

Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |biotransformation Target : Klebsiella terrigena SL-2 Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography

Citation

Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |biotransformation Target : Pantoea agglomerans SL-1 Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography

Citation

Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |biotransformation Target : Rahnella aquatilis ML-1 Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography

Citation

Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |biotransformation Target : Rahnella aquatilis YL-1 Bioassay : incubation of title comp.with cell suspension in Tris-HCl buffer (25 deg C); extraction; chromatography

Citation

Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details

Effect

Antifungal

Assay Description

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Target : Pytium ultimum Bioassay : potato-dectrose agar test; 2 day incubation at 25 deg C in dark

Results

illustrative representation of antifungal activity

Citation

Hashidoko, Yasuyuki; Itoh, Eriko; Yokota, Kentaro; Yoshida, Tadashi; Tahara, Satoshi

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 11 p. 2474 - 2478 Title/Abstract Full Text View citing articles Show Details

Results

utilization as substrate by Citrobacter sp., strain 64-1 at 0.2percent (28 deg C, 24 h)

Citation

Yoshida, Hajime; Tani, Yoshiki; Yamada, Hideaki

Agricultural and Biological Chemistry, 1982 , vol. 46, # 10 p. 2539 - 2546 Title/Abstract Full Text Show Details

Effect

Antioxidant

Assay Description

Target : human plasma low density lipoprotein


Bioassay : TBARS levels in intact/UVB irradiated low density lipoprotein: 0.028/0.720 nmol malonaldehyde/mg protein plasma from fresh blood obtained from healthy adults; PBS, pH 7.4; incubated for 30 min; treated by UVB (280-350 nm) for up to 480 min; thiobarbituric acid reactive substances (TBARS) and relative electrophoretic mobility (REM) determined

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Results

at 10/100 μmol/l title comp. significantly decreased TBARS level induced by UVB irradiation (to 0.365/0.203 nmol malonaldehyde/mg protein); at 100 μmol/l title comp. did not change REM of low density lipoprotein

Citation

Hsieh, Chiu-Lan; Yen, Gow-Chin; Chen, Hui-Yin

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 15 p. 6151 - 6155 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

human erythrocyte

Assay Description

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Bioassay : HFG: hemoglobin-free ghost; GSH: glutathione; TBARS: thiobarbituric acid reactive substances; GPx: glutathione peroxidase cells from fresh blood obtained from healthy adults; PBS; incubated for 4 h; treated by UVB (280-350 nm) for 30-120 min; HFG and hemolysate prepared; GSH content and TBARS in HFG and GSH content and intracellular activities in hemolysate measured

Results

title comp. reduced UVB-induced oxidative damage (decreased TBARS formation in conc.-dependent manner, prevented GSH loss, inhibited GPx inactivity)

Citation

Hsieh, Chiu-Lan; Yen, Gow-Chin; Chen, Hui-Yin

Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 15 p. 6151 - 6155 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : DP binding protein binding affinity Bioassay : serum albumin A3782 circular dichroism study; DP: diazepam

Citation

Nozaki, Akiko; Kimura, Toshikiro; Ito, Hideyuki; Hatano, Tsutomu

Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 9 p. 1019 - 1023 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : PB binding protein binding affinity Bioassay : serum albumin A3782 circular dichroism study; PB: phenylbutazone

Citation

Nozaki, Akiko; Kimura, Toshikiro; Ito, Hideyuki; Hatano, Tsutomu

Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 9 p. 1019 - 1023 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : hypoxanthine/xanthine oxidase HPLC; DHBA production was determined

Citation

Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.

Food Chemistry, 2012 , vol. 133, # 3 p. 697 - 706 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : oxygen radical ORAC: oxygen reducing absorbance capacity; 1 ORAC unit equals the inhibition of the declining fluorescence produced by 1 μmol/l of trolox

Results

ORAC 1.18 units


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Citation

Khallouki, Farid; Haubner, Roswitha; Erben, Gerhard; Ulrich, Cornelia M.; Owen, Robert W.

Food Chemistry, 2012 , vol. 133, # 3 p. 697 - 706 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

human Hep G2

Assay Description

Effect : peroxyl radical-induced DCFH oxidation DCFH: 2',7'-dichlorofluorescin; QE: quercetin; peroxyl radicals generated from ABAP (2,2'-azobis(2-amidinopropane)); cells washed with PBS between antioxidant and ABAP treatment

Results

CAA cellular antioxidant activity 1.53 μmol QE/100 μmol

Citation

Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

human Hep G2

Assay Description

Effect : peroxyl radical-induced DCFH oxidation DCFH: 2',7'-dichlorofluorescin; QE: quercetin; peroxyl radicals generated from ABAP (2,2'-azobis(2-amidinopropane)); no PBS wash between antioxidant and ABAP treatment

Results

CAA cellular antioxidant activity 9.08 μmol QE/100 μmol

Citation

Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

Effect

Anti-Atherogenis

Biological material

Mus musculus

Assay Description

Effect : cellular oxidative stress Bioassay : J774 A.1 macrophage

Results

cellular oxidative stress reduction 30 %

Citation

Aviram, Michael; Volkova, Nina; Dreher, Mark; Rosenblat, Mira; Coleman, Raymond; Reddy, Muntha Kesava; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 3 p. 1148 - 1157 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidant Bioassay : 2,2'-azobis(2-methylpropionamidine) dihydrochloride ORAC: oxygen radical absorbance capacity; 1 ORAC unit equals the inhibition of the declining fluorescence produced by 1 μmol/l Trolox

Results

IC inhibitory concentration 1.94

Citation

Barreto, Jacqueline C.; Trevisan, Maria T. S.; Hull, William E.; Erben, Gerhard; De Brito, Edy S.; Pfundstein, Beate; Wuertele, Gerd; Spiegelhalder, Bertold; Owen, Robert W.

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 14 p. 5599 - 5610 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : DPPH radical Target : DPPH radical Bioassay : 1,1-diphenyl-2-picrylhydrazyl radical SC50: concentration of title comp. necessary for 50% reduction of DPPH radical


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Results

SC50 13 μmol/l

Citation

Gao, Da-Fang; Zhang, Ying-Jun; Yang, Chong-Ren; Chen, Ke-Ke; Jiang, Hong-Jian

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 16 p. 7517 - 7521 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : antioxidative Bioassay : 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid radical cation

Results

TEAC Trolox equivalent antioxidant capacity 2.6

Citation

Walker, Richard B.; Everette, Jace D.

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 4 p. 1156 - 1161 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

human

Assay Description

Effect : Cu2+-induced diene conjugation Bioassay : blood low density lipoprotein LDL: low-density lipoprotein; δTlag: is lag phase of LDL oxidation between title comp. treated group and CuSo4-treated group

Results

δTlag > 12 h

Citation

Huang, Din-Wen; Kuo, Yueh-Hsiung; Lin, Fang-Yi; Lin, Yun-Lian; Chiang, Wenchang

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 6 p. 2259 - 2266 Title/Abstract Full Text View citing articles Show Details

Biological material

Escherichia coli

Assay Description

Effect : ATP hydrolysis activity enzyme activity Target : hepatitis C virus NS3h helicase Species : Escherichia coli BL21(DE3) colorimetry-based ATP hydrolysis assay

Citation

Yu, Mi-Sun; Lee, June; Lee, Jin Moo; Kim, Younggyu; Chin, Young-Won; Jee, Jun-Goo; Keum, Young-Sam; Jeong, Yong-Joo

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4049 - 4054 Title/Abstract Full Text View citing articles Show Details

Biological material

Escherichia coli

Assay Description

Effect : dsDNA unwinding activity enzyme activity Target : SARS CoV nsP13 helicase Species : Escherichia coli Rosetta fluorescence resonance energy transfer (FRET)-based double-strand (ds) DNA unwinding assay; SARS CoV: severe acute respiratory syndrome coronavirus

Citation

Yu, Mi-Sun; Lee, June; Lee, Jin Moo; Kim, Younggyu; Chin, Young-Won; Jee, Jun-Goo; Keum, Young-Sam; Jeong, Yong-Joo

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4049 - 4054 Title/Abstract Full Text View citing articles Show Details

Biological material

Escherichia coli

Assay Description

Effect : dsDNA unwinding activity enzyme activity Target : hepatitis C virus NS3h helicase Species : Escherichia coli BL21(DE3) fluorescence resonance energy transfer (FRET)-based double-strand (ds) DNA unwinding assay


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Citation

Yu, Mi-Sun; Lee, June; Lee, Jin Moo; Kim, Younggyu; Chin, Young-Won; Jee, Jun-Goo; Keum, Young-Sam; Jeong, Yong-Joo

Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4049 - 4054 Title/Abstract Full Text View citing articles Show Details

Effect

Mutagenic

Assay Description

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Citation

Martinez, A.; Urios, A.; Blanco, M.

Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details

Effect

Mutagenic

Assay Description

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oxidative mutagenesis in the abs. of S9 mix; mutagenesis inhibited by S9

Citation

Martinez, A.; Urios, A.; Blanco, M.

Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details

Effect

Mutagenic

Martinez, A.; Urios, A.; Blanco, M.

Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details

Effect

Mutagenic

Target : Escherichia coli IC208 Bioassay : mutY oxyR WP2 uvrA/pKM101 bacterial strain in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; number of revertants per plates counted

Citation

Martinez, A.; Urios, A.; Blanco, M.

Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details

Effect

Mutagenic

Assay Description

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Target : Escherichia coli IC206 Bioassay : mutY WP2 uvrA/pKM101 bacterial strain in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; number of revertants per plates counted

Citation

Assay Description

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Target : Escherichia coli IC203 Bioassay : WP2 uvrA/pKM101 bacterial strain deficient in OxyR in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; with and without metabolic activation with S9 mix; number of revertants per plates counted

Results

Assay Description

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Target : Escherichia coli IC188 Bioassay : parent WP2 uvrA/pKM101 bacterial strain in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; number of revertants per plates counted

Target : Escherichia coli IC204 Bioassay : mut+ WP2 uvrA/pKM101 bacterial strain in vitro; plate incorporation assay; Difco agar; minimal ET4 plates; 37 deg C; 2 d; number of revertants per plates counted

Citation

Martinez, A.; Urios, A.; Blanco, M.

Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details

Effect

Antimicrobial

Assay Description

Target : ATCC 10231 of Candida albicans


Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms

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Results

title compound was found to be selective inhibitor of Candida albicans and zone of inhibition amount 5-4 mm at 1 - 10 mg/ml

Citation

Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.

Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details

Effect

Antimicrobial

Assay Description

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Citation

Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.

Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details

Effect

Antimicrobial

Assay Description

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Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.

Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details

Effect

Antimicrobial

Target : ATCC 6538 of Staphylococcus aureus Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms

Citation

Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.

Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details

Effect

Antimicrobial

Assay Description

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Target : ATCC 11975 of Lactobacillus acidophilus Bioassay : C. albicans is an opportunistic organism that can cause various infections of the skin, mouth and vagina. C. albicans and other Candida strains are part of normal human microbial flora, but under certain circumstances may cause complications, such as infection. The challenge to the medical field is

Citation

Assay Description

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Target : ATCC 16404 of Aspergillus niger Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms

Target : ATCC 8739 of Escherichia coli Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms

Citation

Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.

Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details

Effect

Antimicrobial

Assay Description

Citation

Target : ATCC 9027 of Pseudomonas aeruginosa Bioassay : Natural compounds were evaluated for anti-microbial activity using the zone of inhibition test (ASTM E214901). The activity against five types of microorganisms: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Aspergillis niger and Candida albicans, was evaluated. These microorganisms Greene, Sharon Linda; Huang, Yanbin; Huang, Lei; Weart, Ilona F.; Yang, Shu-Ping; Malik, Sohail; Johnson, Robert B.

Patent: US2006/134237 A1, 2006 ; Title/Abstract Full Text Show Details


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Biological material

Calloselasma rhodostoma

Assay Description

Effect : fibrinogenolytic activity anti-snake venom metalloproteinase activity Bioassay : venom

Results

complete inhibition concentration 14.11 μmol/l

Citation

Pithayanukul, Pimolpan; Leanpolchareanchai, Jiraporn; Saparpakorn, Patchreenart

Molecules, 2009 , vol. 14, # 9 p. 3198 - 3213 Title/Abstract Full Text View citing articles Show Details

Biological material

Naja kaouthia

Assay Description

Effect : fibrinogenolytic activity anti-snake venom metalloproteinase activity Bioassay : venom

Results

complete inhibition concentration 7.05 μmol/l

Citation

Pithayanukul, Pimolpan; Leanpolchareanchai, Jiraporn; Saparpakorn, Patchreenart

Molecules, 2009 , vol. 14, # 9 p. 3198 - 3213 Title/Abstract Full Text View citing articles Show Details

Results

in vitro study on antioxidant effect: inhibition of oxygen consumption and malondialdehyde formation due to lipid peroxidation in rat heart mitochondria

Citation

Hong; Wang; Huang; Hsu

Journal of Pharmacy and Pharmacology, 1995 , vol. 47, # 2 p. 138 - 142 Title/Abstract Full Text View citing articles Show Details

Results

antioxidant activity (inhibitor of bleaching of crocin)

Citation

Cavin, Alexandre; Hostettmann, Kurt; Dyatmyko, Wahjo; Potterat, Olivier

Planta Medica, 1998 , vol. 64, # 5 p. 393 - 396 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of his+ revertants Target : Salmonella typhimurium TA 100 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against captan (CP)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of CP (100 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. dose-dependently reduced the number of CP-induced His+ revertants with 51 percent inhibition of revertant colonies at the highest dose

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of his+ revertants Target : Salmonella typhimurium TA 100 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against nitroso-N-methylurea (MNU)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of MNU (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. dose-dependently reduced the number of MNU-induced His+ revertants with 18 percent inhibition of revertant colonies at the highest dose

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details


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Effect

Antimutagenic

Assay Description

Effect : number of his+ revertants Target : Salmonella typhimurium TA 100 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of MNNG (1 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. dose-dependently reduced the number of MNNG-induced His+ revertants with 63 percent inhibition of revertant colonies at the highest dose

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of his+ revertants Target : Salmonella typhimurium TA 97 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against folpet (FP)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of FP (100 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. dose-dependently reduced the number of FP-induced His+ revertants with 64 percent inhibition of revertant colonies at the highest dose

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of His+ revertants Target : Salmonella typhimurium TA 97 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against ICR-170-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. with ICR-170 (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. had a little effect on the number of ICR-191-induced His+ revertants with 11 percent inhibition of revertant colonies at the highest dose

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of His+ revertants Target : Salmonella typhimurium TA 97 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against ICR-191-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. with ICR-191 (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. dose-dependently reduced the number of ICR-191-induced His+ revertants with 32 percent inhibition of revertant colonies at the highest dose

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of His+ revertants Target : Salmonella typhimurium TA 97 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against 4-nitroquinoline-N-oxide (4-NQNO)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. with of 4-NQNO (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants


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Results

title comp. dose-dependently reduced the number of 4-NQNO-induced His+ revertants with 43 percent inhibition of revertant colonies at the highest dose

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of His+ revertants Target : Salmonella typhimurium TA 98 Bioassay : phosphate buffer (PB); estimation of antimutagenic effect of title comp. against 9-aminoacridine (9AA)-induced mutations in vitro; title comp. in PB, pH 7.4; Ames test; title comp. was incub. in the pres. of 9AA (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. dose-dependently reduced the number of 9AA-induced His+ revertants with 83 percent inhibition of revertant colonies at the highest dose

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of his+ revertants Target : Salmonella typhimurium TA 98 Bioassay : title comp. in phosphate buffer (PB; pH 7.4); estimation of the number of His+ revertants per plate; study of the mechanism of antimutagenic effect of title comp. against 9-aminoacridine (9AA; 10 μg/plate)-induced mutations in vitro; Ames test; title comp., 9AA and cells were incub. for 30 min at 37 deg C in var. combin. (all together; title comp.+9AA for 15 min, then cells; cells + title comp. for 15 min, then 9AA; cells + 9AA for 15 min, then cells); 30-min Ames test

Results

the greatest inhibition of 9AA-induced mutagenesis was obs. when title comp. and bacteria were preincubated together before exposing to 9AA

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of His+ revertants Target : Salmonella typhimurium TA 98 Bioassay : title comp. in phosphate buffer (PB, pH 7.4); S9 mix was prepared from Aroclor 1254-induced Sprague-Dawley rats; estimation of antimutagenic effect of title comp. against aflatoxin B1 (AFB1)induced mutations in vitro; Ames test with metabolic activation; title comp. was incub. in the pres. of AFB1 (1 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. had a little effect on the number of AFB1-induced His+ revertants with 20 percent inhibition of revertant colonies at 100 μg/plate

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Effect

Antimutagenic

Assay Description

Effect : number of His+ revertants Target : Salmonella typhimurium TA 98 Bioassay : title comp. in phosphate buffer (PB, pH 7.4); S9 mix was prepared from Aroclor 1254-induced Sprague-Dawley rats; estimation of antimutagenic effect of title comp. against benzo(a)pyrene (B(a)P)-induced mutations in vitro; Ames test with metabolic activation; title comp. was incub. in the pres. of B(a)P (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. dose-dependently reduced the number of B(a)P-induced His+ revertants with 20 percent inhibition of revertant colonies at 100 μg/plate

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details


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Effect

Antimutagenic

Assay Description

Effect : number of His+ revertants Target : Salmonella typhimurium TA 98 Bioassay : title comp. in phosphate buffer (PB, pH 7.4); S9 mix was prepared from Aroclor 1254-induced Sprague-Dawley rats; estimation of antimutagenic effect of title comp. against 2acetylaminofluorene (AAF)-induced mutations in vitro; Ames test with metabolic activation; title comp. was incub. in the pres. of AAF (10 μg/plate) with cells for 30 min at 37 deg C; cells were transferred into minimal agar plates and incub. for 48 h; estim. of the number of His+ revertants

Results

title comp. had a little effect on the number of AAF-induced His+ revertants with 20 percent inhibition of revertant colonies at 100 μg/plate

Citation

Hour, Tzyh-Chyuan; Liang, Yu-Chih; Chu, Iou-Sen; Lin, Jen-Kun

Food and Chemical Toxicology, 1999 , vol. 37, # 6 p. 569 - 579 Title/Abstract Full Text View citing articles Show Details

Biological material

Staphylococcus aureus

Assay Description

Effect : |drug interaction Bioassay : methicillin resistant S. aureus used; β-lactam antibiotics: oxacillin, cefmetazole, imipenem, benzylpenicillin; other antimicrobial agents: erythromycin, fosfomysin, ofloxacin, streptomycin, tetracycline, vancomycin MICs of β-lactam antibiotics and other antimicrobial agents determined in presence of title comp.

Citation

Shimizu; Shiota; Mizushima; Ito; Hatano; Yoshida; Tsuchiya

Antimicrobial Agents and Chemotherapy, 2001 , vol. 45, # 11 p. 3198 - 3201 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : control: H2O; TNF: tumor necrosis factor; IKK: IκB kinase; GST: glutathione S-transferase cytosolic extract from TNFα-stimulated cells was treated with title comp. for 20 min on ice; IKK activity determined in cytosolic extract by phosphorylation of IκBα-GST fusion protein

Results

title comp. inhibited IKK activity to ca. 70 percent of that in control

Citation

Yang, Fajun; Oz, Helieh S.; Barve, Shirish; De Villiers, Willem J. S.; McClain, Craig J.; Varilek, Gary W.

Molecular Pharmacology, 2001 , vol. 60, # 3 p. 528 - 533 Title/Abstract Full Text View citing articles Show Details

Biological material

Mus musculus Hepa-1c1c7 cell line

Assay Description

Effect : |antagonist Bioassay : AhR: aryl hydrocarbon receptor; TCDD: 2,3,7,8-tetrachlorodibenzo<1,4>dioxin; suppression level: amount of transformed AhRs in percentage to control value TCDD-induced AhR transformation assay; title comp. added to test cells 10 min prior to 0.1 nmol/l TCDD in α-MEM containing 10% FBS under humidified 5% CO2/95% air, incubated at 37 deg C for 2 h; contents of transformed AhRs estimated by ELISA

Citation

Mukai, Rie; Fukuda, Itsuko; Hosokawa, Keizo; Nishiumi, Shin; Kaneko, Atsushi; Ashida, Hitoshi

Bioscience, Biotechnology and Biochemistry, 2005 , vol. 69, # 5 p. 896 - 903 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild + enzyme [Aspergillus nidulans]:Wild

Assay Description

Effect : |enzyme; examination of Bioassay : syringaldazine 0.1 percent (w/v) solution in 95 percent ethanol for detection of peroxidases; reagents added on the medium without fungi (control); results evaluated following the intensity of the color reaction; maximal intensity 5 isolation from soil plates; malt extract agar medium; extracellular phenoloxidases activities detected by direct application of title comp. to the mycelium; noncontaminated soil

Results

extracellular phenoloxidases activities non-contaminated and non-contaminated soil (0)

Citation

Giraud; Guiraud; Kadri; Blake; Steiman

Water Research, 2001 , vol. 35, # 17 p. 4126 - 4136 Title/Abstract Full Text View citing articles Show Details

Target

enzyme [Hypocrea lixii]:Wild


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Assay Description

Effect : |enzyme; examination of Bioassay : syringaldazine 0.1 percent (w/v) solution in 95 percent ethanol for detection of peroxidases; control from Collection Mycology Pharmacy Grenoble; results evaluated following the intensity of the color reaction; maximal intensity 5 isolation from soil plates; malt extract agar medium; extracellular phenoloxidases activities detected by direct application of title comp. to the mycelium; noncontaminated soil

Results

extracellular phenoloxidases activities non-contaminated soil (0)

Citation

Giraud; Guiraud; Kadri; Blake; Steiman

Water Research, 2001 , vol. 35, # 17 p. 4126 - 4136 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

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Results

title comp. resulted to a dose dependent increase of FRAP in plasma; FRAP levels in title comp.-exposed plasma lower than ascorbic acid at all conc.; fig.

Citation

DeGraft-Johnson, Jeffrey; Kolodziejczyk, Krzysztof; Krol, MacIej; Nowak, Piotr; Krol, Boguslaw; Nowak, Dariusz

Basic and Clinical Pharmacology and Toxicology, 2007 , vol. 100, # 5 p. 345 - 352 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

human HL-60 cell line

Assay Description

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Bioassay : DCF-DA: 2',7'-dichlorofluorescein diacetate in vitro; cells differentiated for 5 d in DMSO solution; scavenging effect of title comp. on exogeneous H2O2 assayed; 1E6 cells/mL; Hanks' balanced salt solution; incubation 90 min; 37 deg C; residual H2O2 determined by DCF-DA method in flow cytometer

Results

conc.-response profile; title comp. exhibited weak scavenging activity in a dose-dependent manner

Citation

Lin, Jen-Kun; Chen, Ping-Chung; Ho, Chi-Tang; Lin-Shiau, Shoei-Yn

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 7 p. 2736 - 2743 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

human HL-60 cell line

Assay Description

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Target : human plasma Bioassay : TPTZ: 2,4,6-tripirydyl-s-triazyne; control: plasma incub. in water with or without DMSO; FRAP: ferric-reducing ability power; positive controls: ascorbic acid or Trolox(R) plasma incub. with title comp. in the presence of FeCl3 and TPTZ for 10 min at 37 deg C; pH 3.6; increase in absorbance at 593 nm monitored

Bioassay : Hanks' balanced salt solution; superoxide level quantified for 2 h by chemiluminescence assay; PMA: phorbol-12-myristate-13-acetate in vitro; cells differentiated for 5 d in DMSO solution; inhibition of PMA (100 ng/mL)-stimulated superoxide production assayed; 2.5E5 cells; cells preincubated with title comp. and 200 μM lucigenin for 5 min, then stimulated with PMA

Results

conc.-response profile; title comp. potentiated PMA-stimulated superoxide production

Citation

Lin, Jen-Kun; Chen, Ping-Chung; Ho, Chi-Tang; Lin-Shiau, Shoei-Yn

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 7 p. 2736 - 2743 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

human HL-60 cell line

Assay Description

Results

Bioassay : 37 deg C; incubation time 90 min; H2O2 production determined by measuring HRP-mediated scopoletin oxidation using fluorescence assay; PMA: phorbol-12-myristate-13-acetate; HRP: horse radish peroxidase in vitro; cells differentiated for 5 d in DMSO solution; inhibition of PMA (100 ng/mL)-stimulated H2O2 production assayed; 2.5E5 cells; Hanks' balanced salt solution; cells preincubated with title comp., scopoletin, NaN3 and purogallin (1U/mL) for 5 min conc.-response profile; title comp. inhibited H2O2 production in a dose-dependent manner


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Citation

Lin, Jen-Kun; Chen, Ping-Chung; Ho, Chi-Tang; Lin-Shiau, Shoei-Yn

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 7 p. 2736 - 2743 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

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Target : human erythrocyte membrane ghosts Bioassay : spectrophotometry; control: contained no title comp.; TBA: thiobarbituric acid in vitro; antioxidant activity against Fe2+-induced lipid oxidation assayed; human blood drawn from healthy graduate students; 5 μmol/l FeSO4; PBS, pH 7.2; 37 deg C; lipid oxidation measured by TBA assay at 0, 36 and 72 h and recorded as TBA number

Results

title comp. significantly delayed Fe2+-induced lipid oxidation when compared with control, TBA number/control/dose(μmol/l) after 72 h incubation: 0.366-0.374-0.381/0.531-0.520-0.519/5 and 0.2740.273-0.281-0.271/0.531-0.520-0.519-0.535/10,

Citation

Liao, Kuei-Long; Yin, Mei-Chin

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 6 p. 2266 - 2270 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Biological material

human thrombocyte

Assay Description

Effect : |enzyme; induction of Bioassay : incubated for 20 min; liquid scintillation spectrometry effect on M-form phenolsulfotransferase (PST-M) activity evaluated; platelets obtained from blood collected from healthy adult volunteers; 10 μmol/l dopamine; 6.7 μmol/l <35S>-3'-phosphoadenosine-5'-phosphosulfate; assay buffer, pH 7.0; 37 deg C

Results

at 2.5/5.0/7.5 μmol/l title comp. promoted PST-M activity by 5/9/10 percent

Citation

Yeh, Chi-Tai; Shih, Ping-Hsiao; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 13 p. 4139 - 4143 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Biological material

human thrombocyte

Assay Description

Effect : |enzyme; induction of Bioassay : incubated for 20 min; liquid scintillation spectrometry effect on P-form phenolsulfotransferase (PST-P) activity evaluated; platelets obtained from blood collected from healthy adult volunteers; 3 μmol/l p-nitrophenol; 6.7 μmol/l <35S>-3'-phosphoadenosine-5'-phosphosulfate; assay buffer, pH 7.0; 37 deg C

Results

at 2.5/5.0/7.5 μmol/l title comp. promoted PST-P activity by 12/26/28 percent

Citation

Yeh, Chi-Tai; Shih, Ping-Hsiao; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 13 p. 4139 - 4143 Title/Abstract Full Text View citing articles Show Details

Results

inhibitor (IC 50 (μM)) of wheat embryo Ca2+-dependent protein kinase (MLCP-substrate) (not active); or (III-S histones - substrate) (not active)

Citation

Polya; Wang Bing Hui; Foo

Phytochemistry, 1995 , vol. 38, # 2 p. 307 - 314 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : nalbuphine metabolism; inhibition of Target : liver microsome of Sprague-Dawley rat Bioassay : Experiment 1. In Vitro Experiment of UGT2B Inhibitor Material and Method: 1. The Preparation of UGT2B Inhibitor In the following experiment, 27 different kinds of CHEs were used as UGT2B inhibitor in this invention. These CHEs are pure compounds available commercially, and were purchased from Sigma

Results

title compound showed 8.051 - 15.842 % inhibitory effect at a concentration of 8.5 - 850 μmol/l

Citation

National Defense Medical Center; National Defense University

Patent: US2006/40875 A1, 2006 ;


Title/Abstract Full Text Show Details

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Results

in vitro no inhibition of insulin-stimulated lipogenesis in male Wistar rats adipose tissue at conc. up to 1 mM

Citation

Ong; Khoo; Das

Experientia, 1995 , vol. 51, # 6 p. 577 - 584 Title/Abstract Full Text View citing articles Show Details

Results

antioxidant acitivity by the rabbit erythrocyte membrane ghost method, IC50 = 106 μM

Citation

Okamura, Hideo; Mimura, Akio; Yakou, Yasuko; Niwano, Mitsuru; Takahara, Yoshimasa

Phytochemistry (Elsevier), 1993 , vol. 33, # 3 p. 557 - 562 Title/Abstract Full Text View citing articles Show Details

Results

Growth inhibitory activity against larvae of Heliothis virescens; EC50: 7.40 mmol/kg diet

Citation

Klocke, James A.; Wagenen, Brad Van; Balandrin, Manuel F.

Phytochemistry (Elsevier), 1986 , vol. 25, # l p. 85 - 92 Title/Abstract Full Text Show Details

Results

inactivation of reed β-glucan synthase

Citation

Mason, Theresa L.; Wasserman. Bruce P.

Phytochemistry (Elsevier), 1987 , vol. 26, # 8 p. 2197 - 2202 Title/Abstract Full Text View citing articles Show Details

Results

no inhibiting activity against alpha-acid oxidase enzyme

Citation

Williams, Elizabeth A.; Menary, Robert C.

Phytochemistry (Elsevier), 1988 , vol. 27, # 1 p. 35 - 40 Title/Abstract Full Text View citing articles Show Details

Results

inhibitory activity (percent) against phenylalanine ammonia-lyase derived from: sweet potato 72, pea 60, yeast 3; inhibition constant 8.8E-5 M (sweet potato)

Citation

Sato, Toshitsugu; Kiuchi, Fumiyuki; Sankawa, Ushio

Phytochemistry (Elsevier), 1982 , vol. 21, # 4 p. 845 - 850 Title/Abstract Full Text View citing articles Show Details

Results

inhibitory effect on glucan synthesis by glucosyltransferase from Streptococcus mutans

Citation

Kakiuchi; Hattori; Nishizawa; Yamagishi; Okuda; Namba

Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 720 - 725 Title/Abstract Full Text View citing articles Show Details

Results

no shows the blood urea nitrogen (BUN)-decreasing activity in rat serum

Citation

Shibutani; Nagasawa; Oura; Nonaka; Nishioka

Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 3 p. 874 - 878 Title/Abstract Full Text View citing articles Show Details

Results

inhibitory effect on TPA-induced inflammation in mice

Citation

Yasukawa; Takido; Takeuchi; Nakagawa

Chemical and pharmaceutical bulletin, 1989 , vol. 37, # 4 p. 1071 - 1073 Title/Abstract Full Text View citing articles Show Details


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Results

inhibition of mutagenicity of 3-amino-1-methyl-5H-pyrido<4,3-b>indole, using Salmonella typhimurium TA98 and TA100

Citation

Okuda; Mori; Hayatsu

Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 9 p. 3755 - 3758 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : endothelium-dependent relaxation; effect on Target : aortic ring of New Zealand White rabbit Bioassay : Effect of different procyanidins on endothelium-dependent relaxation was tested in an ex vivo experiment performed as previously described by Karim et al., J. Nutrl Suppl., 130 (8S): 2105S2108S (2000), the relevant portions of which are hereby incorporated herein by reference. The advantage of using

Results

HUVEC-mediated MTT reduction following 5 subsequent 24 h treatment with test compound at 10 μM; % MTT reduction near 50

Citation

Mars, Incroporated

Patent: US2005/277600 A1, 2005 ; Title/Abstract Full Text Show Details

Assay Description

Effect : nitric oxide production; effect on Target : human umbilical vein endothelial cell (HUVEC) of human Bioassay : Test compounds were evaluated with respect to their potential to acutely (24 hour) and chronically (5 doses given in 24 hour intervals) modulate NO production. Positive controls (acetylcholine and/or histamine) and negative control L-NNMA (NO synthase inhibitor) were included in all experiments. Cell

Results

Nitric oxide production induced folowing 24 h treatment with test compound at 20 μM - concentration near 1 μM

Citation

Mars, Incroporated

Patent: US2005/277600 A1, 2005 ; Title/Abstract Full Text Show Details

Effect

Chemoprotective

Assay Description

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Results

protective activity against the cell damage induced by superoxide anion radicals; little effect on survival at 50 μM but 43.5-79.7 percent survival at 100-1000 μM (control: 36.9 percent)

Citation

Masaki; Atsumi; Sakurai

Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 1 p. 59 - 63 Title/Abstract Full Text View citing articles Show Details

Effect

Chemoprotective

Assay Description

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Target : dermal fibroblasts from ICR mice Bioassay : 37 deg C; ESR spin-trapping after 1 d of cultivation, cells were exposed to 1.5 mM hypoxanthine, 500 unit/ml catalase, 40 munit/ml xanthine oxidase dissolved in Hank's buffer HBS in the presence of test agent

Target : dermal fibroblasts from ICR mice Bioassay : 37 deg C fibroblasts treated with test agent for 24 h, after washing to remove it, fibroblasts were placed in contact with superoxide anions generated by hypoxanthine-xanthine oxidase HPXXOD catalase system

Results

survival of the control and pre-treated (200 μM) fibroblasts were 17.7 percent and 25.4 percent

Citation

Masaki; Atsumi; Sakurai

Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 1 p. 59 - 63 Title/Abstract Full Text View citing articles Show Details

Effect

Phytotoxic

Biological material

wheat


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Results

100 percent inhibition of root growth of germinated wheat

Citation

Shukla; Srivastava, Anil; Kumar, Sushil

Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 6 p. 705 - 708 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

K-562 cell line

Assay Description

428 of 515

Results

IC50: 2.22

Citation

Hou; Peng; Liu; Lin; Sun

Planta Medica, 2000 , vol. 66, # 7 p. 624 - 626 Title/Abstract Full Text View citing articles Show Details

Effect

Antibiotic

Assay Description

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Target : human HL cells Bioassay : FITC: fluorescein isothiocyanate-conjugated chlamydial genus-specific antibody; C. pneumoniae: Chlamydia pneumoniae isolate Kajaani 7 (K7), 1E3 inclusion-forming units/well cell monolayers infected with C. pneumoniae; after 60-min centrifugation, title comp. added for 72 h at 37 deg C, then cells washed and fixed; chlamydial inclusions stained with FITC and examined under fluorescence microscope

Results

50 μmol/l title comp. caused ca. 27 percent inhibition of inclusion forming

Citation

Alvesalo; Vuorela; Tammela; Leinonen; Saikku

Biochemical Pharmacology, 2006 , vol. 71, # 6 p. 735 - 741 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

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Bioassay : 4E4 cells/ml at a log phase incubated with title comp. in 96-well plates at 37 deg C for 48 h; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide added, 4 h; SDS-iBuOH-HCl added; after 12 h at r.t. optical density at 570 nm and 630 nm measured

Target : human HL cells Bioassay : LDH: lactate dehydrogenase LDH levels determined after 2 and 72 h exposure to title comp. by using commercial LDH test kit; dead cells counted after 72 h incubation with title comp. via Trypan blue staining

Citation

Alvesalo; Vuorela; Tammela; Leinonen; Saikku

Biochemical Pharmacology, 2006 , vol. 71, # 6 p. 735 - 741 Title/Abstract Full Text View citing articles Show Details

Results

antioxidant activity

Citation

Takahashi, Hironobu; Iuchi, Miho; Fujita, Yoshimi; Minami, Hiroyuki; Fukuyama, Yoshiyasu

Phytochemistry, 1999 , vol. 51, # 4 p. 543 - 550 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |antagonist Target : Sprague-Dawley rat liver cytosol Bioassay : effect on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced aryl hydrocarbon receptor transformation evaluated by electrophoretic mobility shift assay; assay buffer, pH 7.4; 20 deg C; incubated for 10 min; 0.1 nmol/l TCDD added for further 2 h

Citation

Fukuda, Itsuko; Sakane, Iwao; Yabushita, Yoshiyuki; Kodoi, Rie; Nishiumi, Shin; Kakuda, Takami; Sawamura, Shin-Ichi; Kanazawa, Kazuki; Ashida, Hitoshi

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 9 p. 2499 - 2506 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild


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Assay Description

Effect : |enzyme; inhib. of Bioassay : chitin synthase III prepared from recombinant Saccharomyces cerevisiae ECY38-38A (pWJC6) membrane suspension incub. in Tris-HCl buffer pH 7.5 with Mg(OAc)2, UDP-<U-14C>-Nacetylglucosamine, trypsin, title comp. at 30 deg C, 15 min; stopped by soybean trypsin inhibitor; N-acetylglucosamine added, 90 min, 30 deg C; amount of chitin determined

Citation

Hwang; Ahn; Lee; Kim; Bok

Planta Medica, 2001 , vol. 67, # 6 p. 501 - 504 Title/Abstract Full Text View citing articles Show Details

Effect

Vasoconstrictor

Assay Description

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Results

title comp. inhibited ACh-induced relaxation; effect did not depend on cyclooxygenase activity (diagram)

Citation

Sanae, Fujiko; Miyaichi, Yukinori; Hayashi, Hisao

Planta Medica, 2002 , vol. 68, # 8 p. 690 - 693 Title/Abstract Full Text View citing articles Show Details

Effect

Vasoconstrictor

Assay Description

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Target : Wistar rat aortic strip Bioassay : control: without title comp.; further investigation on mechanism of action using indomethacin (IM), BQ610, L-NAME and L-arginine; L-NAME: NG-nitro-L-arginine methyl ester thoracic aorta strips with or without endothelium were mounted in organ bath at 37 deg C; resting tension was adjusted to 1 g; strips precontracted with phenylephrine and title comp. was added cumulatively; isometric tension was assessed

Results

title comp. in conc.-dependent manner stimulated further contraction of phenylephrine-precontructed strips with intact endothelium; effect was inhibited by NO synthesis activation and did not depend on endothelin receptors and cyclooxygenase

Citation

Sanae, Fujiko; Miyaichi, Yukinori; Hayashi, Hisao

Planta Medica, 2002 , vol. 68, # 8 p. 690 - 693 Title/Abstract Full Text View citing articles Show Details

Effect

Vasoconstrictor

Assay Description

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Target : Wistar rat aortic strip Bioassay : control: without title comp.; ACh: acetylcholine; further investigation of mechanism of action using indomethacin intact thoracic aorta strips were mounted in organ bath at 37 deg C; strips incubated with title comp. for 15 min, contracted by phenylephrine; ACh-induced relaxation was assessed

Target : Wistar rat aortic strip Bioassay : control: without title comp. thoracic aorta strips without endothelium were mounted in organ bath at 37 deg C; strips incubated with title comp. for 15 min and contracted by phenylephrine; sodium nitroprusside-induced relaxation was assessed

Results

title comp. inhibited sodium nitroprusside-induced relaxation (diagram)

Citation

Sanae, Fujiko; Miyaichi, Yukinori; Hayashi, Hisao

Planta Medica, 2002 , vol. 68, # 8 p. 690 - 693 Title/Abstract Full Text View citing articles Show Details

Effect

Vasoconstrictor

Assay Description

Target : Wistar rat aortic strip Bioassay : control: without title comp. thoracic aorta strips without endothelium were mounted in organ bath at 37 deg C; strips incubated with title comp. for 15 min; contracted by phenylephrine and prostacyclin-induced relaxation was assessed

Results

title comp. inhibited prostacyclin-induced relaxation (diagram)

Citation

Sanae, Fujiko; Miyaichi, Yukinori; Hayashi, Hisao

Planta Medica, 2002 , vol. 68, # 8 p. 690 - 693 Title/Abstract Full Text View citing articles Show Details


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Target

histidine decarboxylase [human]:Wild

Assay Description

Effect : enzyme activity; inhibition of Bioassay : 3.2 mM L-histidine; assay buffer, pH 6.8; 37 deg C; incubated with title comp. for 1 h; formation of histamine measured

Results

title comp. inhibited enzyme activity to ca. 91% of control; fig.

Citation

Nitta, Yoko; Kikuzaki, Hiroe; Ueno, Hiroshi

Journal of agricultural and food chemistry, 2007 , vol. 55, # 2 p. 299 - 304 Title/Abstract Full Text Show Details

Assay Description

Effect : enzyme activity; inhibition of

Citation

Ha, Tae Joung; Kubo, Isao

Journal of agricultural and food chemistry, 2007 , vol. 55, # 2 p. 446 - 451 Title/Abstract Full Text Show Details

Assay Description

Effect : protein cleavage; induction of Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : PARP: poly (ADP-ribose) polymerase cells incubated with title comp. for 6 h; level of procaspase 3 and active caspase 3 (32 and 17 kDa), full and fragmented forms of PARP protein (116 and 85 kDa) measured by Western blotting

Results

title comp. dose-depend. induced cleavage of procaspase 3 into active form and fragmentation of PARP protein; fig.

Citation

Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng

Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : protein level; decrease of Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : cells incubated with title comp. for 2-6 h; level of Bcl-2 protein measured by Western blotting

Results

title comp. dose- and time-depend. decreased Bcl-2 protein amount; fig.

Citation

Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng

Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : protein level; increase of Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : cells incubated with title comp. for 2-6 h; level of cytosolic cytochrome c (cyt c) and Bax protein levels measured by Western blotting

Results

title comp. dose- and time-depend. increased cytosolic cyt c level and Bax protein amount; fig.

Citation

Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng

Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : reactive oxygen species production; increase of Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : further invest. with vitamin C, vitamin E and catalase cells incubated with title comp. for 0.5-2 h; intracellular ROS production detected by flow cytometry using 2',7'-dihydrofluoresceindiacetate; propidium iodide staining

Results

title comp. time-depend. increased ROS production; effect decreased by catalase; fig.

Citation

Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng

Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details

Biological material

human lymphocyte


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Assay Description

Effect : |growth inhibition Bioassay : cells incubated with title comp. for 12 h; cell number counted with hemocytometer

Citation

Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng

Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

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Results

title comp. dose- and time-depend. inhibited cell growth by ca. 2.2-fold at highest conc. after 6 h of incubation (ca. 2-fold inhibition observed for taxol); cell shrinkage observed; effect decreased by catalase; fig.

Citation

Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng

Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details

Effect

Hemolytic

Biological material

human erythrocyte

Assay Description

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Bioassay : cells incubated with title comp. for 15 h; hemolysis analyzed

Citation

Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng

Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |biotransformation Target : recombinant PDC of Lactobacillus plantarum CECT 748T

Bioassay : incubation mixture lacking enzyme used as control; PDC: p-coumaric acid decarboxylase ATCC 14917, DSMZ 20174; incubated with title comp. in phosphate buffer (pH 6.5) at 30 deg C for 4 h; formation of degradation products analyzed by HPLC-DAD

Citation

Rodriguez, Hector; Landete, Jose Maria; Curiel, Jose Antonio; De Las Rivas, Blanca; Mancheno, Jose Miguel; Munoz, Rosario

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 9 p. 3068 - 3072 Title/Abstract Full Text View citing articles Show Details

Effect

Antineoplastic

Biological material

A-549

Assay Description

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Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : 0.5 μg/ml taxol used for reference; further invest. with vitamin C, vitamin E and catalase cells incubated with title comp. for 2-6 h; cell growth and viability assessed by trypan blue exclusion assay; cell morphology analyzed using phase contrast microscopy

PDP was concentration-dependent

Results

inhibition ratio 15.92 - 74.6 percent

Citation

Zhao, Yan-Li; He, Qiu-Xia; Li, Yang; Wang, Si-Feng; Liu, Ke-Chun; Yang, Yong-Ping; Li, Xiao-Li

Molecules, 2010 , vol. 15, # 4 p. 2178 - 2186 Title/Abstract Full Text View citing articles Show Details

Effect

Antiproliferative

Assay Description

Results

Target : 3T3-L1 preadipocytes BCRC 60159 Bioassay : DMEM with 10 percent FBS; humidified 5 percent CO2; 37 deg C; incubated for 24, 48, and 72 h; cell cycle analysis by flow cytometry title comp. did not affect cell cycle profile of cells; however, it markedly time- and conc.-dependently increased accumulation of the sub-G1 phase (apoptotic cells)


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Citation

Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

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Results

title comp. induced LDH leakage in time- and conc.-dependent manner

Citation

Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : positive control: pepstatin A, IC50 = 0.016 μmol/l in vitro; incubation time: 1 h; 37 deg C; fluorescence at 360ex/530em

Citation

Li; Jacob; Pasco; ElSohly; Nimrod; Walker; Clark

Journal of Natural Products, 2001 , vol. 64, # 10 p. 1282 - 1285 Title/Abstract Full Text View citing articles Show Details

Results

no larvicidal activity, no bursting activity in the presence of decanoic acid against larvea of Toxacara canis

Citation

Kiuchi; Tsuda; Kondo; Yoshimura; Nishioka; Nonaka

Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 5 p. 1796 - 1802 Title/Abstract Full Text View citing articles Show Details

Effect

Antiprotozoal

Biological material

Trichomonas vaginalis

Assay Description

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Target : 3T3-L1 preadipocytes BCRC 60159 Bioassay : DMEM with 10 percent FBS; humidified 5 percent CO2; 37 deg C; incubated for 24-72 h; LDH leakage into culture medium analyzed

Bioassay : Example 1 Effect of 1.1 Percent Gallic Acid on the Growth of Trichomonas vaginalis A sterile LYI-S-2 medium was prepared according to the manufacturer's instructions, and the pH of this medium was adjusted to pH 6.0 using 1 N HCl. Gallic acid monohydrate (SIGMA-398225 from Signa Aldrich, USA) was dissolved

Results

title comp. showed activity against Trichomonas vaginalis

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details

Effect

Antiprotozoal

Biological material

Trichomonas vaginalis

Assay Description

Bioassay : Example 2 Effect of Various Concentrations of Gallic Acid on the Growth of Trichomonas vaginalis Essentially the same procedure was performed as described in Example 1, but this time differing concentrations of gallic acid were tested on samples of Trichomonas vaginalis. The gallic acid concentrations

Results

title comp. showed activity against Trichomonas vaginalis

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details


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Effect

Antiprotozoal

Biological material

Gardnerella vaginalis

Assay Description

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Results

title comp. showed activity against Gardnerella vaginalis

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details

Effect

Bacteriostatic

Biological material

Lactobacillus acidophilus

Assay Description

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Bioassay : Example 3 Effect of Gallic Acid on the Growth of Candida albicans and Lactobacillus acidophilus-Zone-of-Inhibition Test A microorganism culture of 105 cfu (colony forming units)/milliliter in a 1× phosphate buffered saline (PBS) solution (diluted from 10× PBS LIQUID CONCENTRATE

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details

Effect

Bacteriostatic

Biological material

Lactobacillus acidophilus

Assay Description

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Bioassay : Example 5 Effect of Gallic Acid on the Growth of Gardnerella vaginalis-Inhibition Test in Solution by Plate Count A test compound of Gardnerella vaginalis was prepared in culture media to form a suspension. Control and gallic acid solutions (0.9 milliliters; 7.5 milligram gallic acid/milliliter) were

Bioassay : Example 4 Effect of Gallic Acid on the Growth of Candida albicans and Lactobacillus acidophilus-Inhibition Tests in Solution by Measuring Optical Density Test compounds of Candida albicans and Lactobacillus acidophilus were dissolved in culture media to form a suspension. Control and gallic acid solutions

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details

Biological material

Candida albicans

Assay Description

Effect : fungostatic Bioassay : Example 3 Effect of Gallic Acid on the Growth of Candida albicans and Lactobacillus acidophilus-Zone-of-Inhibition Test A microorganism culture of 105 cfu (colony forming units)/milliliter in a 1× phosphate buffered saline (PBS) solution (diluted from 10× PBS LIQUID CONCENTRATE

Results

title comp. showed activity against Candida albicans

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details

Biological material

Candida albicans

Assay Description

Effect : fungostatic Bioassay : Example 4 Effect of Gallic Acid on the Growth of Candida albicans and Lactobacillus acidophilus-Inhibition Tests in Solution by Measuring Optical Density Test compounds of Candida albicans and Lactobacillus acidophilus were dissolved in culture media to form a suspension. Control and gallic acid solutions

Results

title comp. showed activity against Candida albicans

Citation

Kimberly-Clark Worldwide, Inc.

Patent: US2006/217443 A1, 2006 ; Title/Abstract Full Text Show Details


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Effect

Antiproliferative

Biological material

human HCT 116 cell line

Assay Description

Effect : antiproliferative Antiproliferative Activities of Isolated Phenolics from Maple Syrup on Colon Cells The antiproliferative activities of phenolics previously isolated from maple syrup extracts are evaluated after both 48 and 72 h of treatment (Table 14). All of the pure compounds inhibited proliferation of the HCT-1

Results

IC50 (μmol/l) = 64.9, 42.1 after 48, 72 h treatment, respectively

Citation

SEERAM, Navindra, P.; LI, Liya; BÉ LAND, Geneviè ve; BARBEAU, Julie

Patent: WO2012/21981 A1, 2012 ; Title/Abstract Full Text Show Details

Assay Description

Effect : tumor cell migration; inhibition of Target : murine colon 26-L5 adenocarcinoma cell line Bioassay : vehicle control; cells stained with 0.5 percent crystal violet for 30 min 2E5 cells incub. with var. conc. of title comp. in RPMI-1640 medium with 0.1 percent bovine serum albumin for 30 min on ice, then added to upper compartment of Transwell chamber, incub. 3 h at 37 deg C; cells stained, migrated cells extracted, absorbance det.

Citation

Ogasawara, Masaru; Matsubara, Toshiyuki; Suzuki, Hideyo

Biological and Pharmaceutical Bulletin, 2001 , vol. 24, # 6 p. 720 - 723 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

Rattus norvegicus liver cell

Assay Description

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Bioassay : incubation: Krebs-Henseleit buffer (pH 7.4); 12.5 mmol/l HEPES; 0.1 percent albumin; 37 deg C male Fisher 344 rats (260-290 g); hepatocytes isolated by collagenase perfusion of the liver; cell viability by trypan blue exclusion

Results

no significant effect on cell death: 20.3 percent (control) vs. 25.5 percent (title comp.);

Citation

Nakagawa, Yoshio; Nakajima, Kazuo; Tayama, Sumiko; Moldeus, Peter

Molecular Pharmacology, 1995 , vol. 47, # 5 p. 1021 - 1027 Title/Abstract Full Text View citing articles Show Details

Results

1,1-diphenyl-2-picrylhydrazyl free radical scavenging activty, IC50=5.0 μg/ml; inhibition of TPA-induced free radical formation in cultured HL-60 cells, IC50=1.5 μg/ml

Citation

Chung, Ha Sook; Chang, Leng Chee; Lee, Sang Kook; Shamon, Lisa A.; Van Breemen, Richard B.; Mehta, Rajendra G.; Farnsworth, Norman R.; Pezzuto, John M.; Kinghorn, A. Douglas

Journal of Agricultural and Food Chemistry, 1999 , vol. 47, # 1 p. 36 - 41 Title/Abstract Full Text View citing articles Show Details

Results

active oxygen scavenging activity in soybean seed

Citation

Yoshiki, Yumiko; Okubo, Kazuyoshi

Bioscience, Biotechnology, and Biochemistry, 1995 , vol. 59, # 8 p. 1556 - 1557 Title/Abstract Full Text Show Details

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : PAPS: 3'-phosphoadenosine 5'-phosphosulfate; P-ST: phenol sulfotransferase in vitro; effect on P-ST activity assayed; phosphate buffer, pH 7.4; 1 μmol/l <35S>PAPS - sulfate donor; 50 μmol/l 2-naphthol - sulfate acceptor; incub. with title comp. for 15 min at 37 deg C; enzyme activity measured by liquid scintillation counting

Citation

Tamura, Hiro'omi; Miyawaki, Atsushi; Yoneshima, Hiroyuki; Mikoshiba, Katsuhiko; Matsui, Michio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 3 p. 234 - 239 Title/Abstract Full Text View citing articles Show Details


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Biological material

Rattus norvegicus

Assay Description

Effect : |biotransformation Bioassay : in vitro; metabolism of title comp. assayed; metabolites detected by HPLC

Results

no metabolites detected

Citation

Zong, Li; Inoue, Makoto; Nose, Mitsuhiko; Kojima, Keisuke; Sakaguchi, Nahoko; Isuzugawa, Kazuto; Takeda, Tadahiro; Ogihara, Yukio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 3 p. 326 - 329 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic

Assay Description

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Results

title comp. produced internucleosomal DNA cleavage

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

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Target : Balb-c mouse thymocytes Bioassay : thymocytes, obtained from crushed mouse thymi, suspended in RPMI-1640 medium (containing HEPES 20mM/l) enriched with fetal calf serum title comp. added to suspension of 4E6 cells in RPMI-1640 medium; after 1 h hydrocortisone hemisuccinate added; incub., 37 deg C, 18-20 h; cells colored with trypan blue and number of living and dead cells counted

Results

significant stimulation of immunological activity at highest dose; percent of thymocyte viability/dose (μg/ml): 98/0.1, 92/1.0, 100/10, 116/50; control: thymus factor X preparation (from calf thymus): 117/50

Citation

Drozd, Janina; Anuszewska, Elzbieta

Acta Poloniae Pharmaceutica - Drug Research, 2003 , vol. 60, # 3 p. 197 - 200 Title/Abstract Full Text View citing articles Show Details

Effect

Antitrypanosomal

Assay Description

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Target : human promyelocytic leukemia HL-60RG cells Bioassay : in vitro; effect on DNA damage assayed; 6E6 cells/ml; incub. with title comp. for 48 h in 5 percent CO2; DNA isolated and subjected to agarose gel electrophoresis

Target : Trypanosoma brucei brucei GUTat 3.1 clone Bioassay : further investigation on mechanism of action using antioxidants superoxide dismutase (SOD) and catalase trypanosome suspension in culture medium (5E5/ml) incubated with title comp. at 37 deg C in 5 percent CO2 for 24 h; number of surviving trypanosomes determined by counting in a haemocytometer

Results

title comp. in concentration-dependent manner induced trypanocidal activity with complete inhibition at 125 μmol/l and higher; reactive oxygen intermediates (superoxide anion and hydrogen peroxide) may mediate title comp. activity

Citation

Nose, Mitsuhiko; Koide, Tatsuo; Morikawa, Kyoko; Inoue, Makoto; Ogihara, Yukio; Yabu, Yoshisada; Ohta, Nobuo

Biological and Pharmaceutical Bulletin, 1998 , vol. 21, # 6 p. 583 - 587 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic

Assay Description

Target : plasmid pBR 322 DNA Bioassay : further investigation on mechanism of action using superoxide dismutase (SOD) and catalase supercoiled DNA incubated with title comp. at 37 deg C for 1 h with or without FeSO4 or H2O2 in sodium phosphate buffer (pH 7.4); agarose gel electrophoresis; strand breaking was assessed

Results

title comp. in concentration-dependent manner activated DNA breaks (figure)

Citation

Nose, Mitsuhiko; Koide, Tatsuo; Morikawa, Kyoko; Inoue, Makoto; Ogihara, Yukio; Yabu, Yoshisada; Ohta, Nobuo

Biological and Pharmaceutical Bulletin, 1998 , vol. 21, # 6 p. 583 - 587 Title/Abstract Full Text View citing articles Show Details


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Target

enzyme:Wild

Assay Description

Effect : enzyme activity; effect on Bioassay : control: acarbose (IC50: 210 μg/ml), 1-deoxynojirimycin (IC50: 27.1 μg/ml) sucrase activity det. using sucrose as substrate; liberated glucose det. by glucoseoxidase method

Citation

Shinde, Jayantrao; Taldone, Tony; Barletta, Michael; Kunaparaju, Naveen; Hu, Bo; Kumar, Sunil; Placido, Jessica; Zito, S. William

Carbohydrate Research, 2008 , vol. 343, # 7 p. 1278 - 1281 Title/Abstract Full Text View citing articles Show Details

Target

alpha-glucosidase [Geobacillus stearothermophilus]:Wild

Assay Description

Effect : enzyme activity; effect on Bioassay : control: acarbose, 1-deoxynojirimycin (IC50: 0.175 μg/ml) enzyme treated with title comp. for 5 min at 37 deg C, pH 6.8, then incub. with p-nitrophenyl α-D-glucuronide for 20 min at 37 deg C; released p-nitrophenol det. spectrophotometrically at 405 nm

Citation

Shinde, Jayantrao; Taldone, Tony; Barletta, Michael; Kunaparaju, Naveen; Hu, Bo; Kumar, Sunil; Placido, Jessica; Zito, S. William

Carbohydrate Research, 2008 , vol. 343, # 7 p. 1278 - 1281 Title/Abstract Full Text View citing articles Show Details

Target

alpha-glucosidase [Saccharomyces cerevisiae]:Wild

Assay Description

Effect : enzyme activity; effect on Bioassay : control: acarbose, 1-deoxynojirimycin (IC50: 83.4 μg/ml) enzyme treated with title comp. for 5 min at 37 deg C, pH 6.8, then incub. with p-nitrophenyl α-D-glucuronide for 20 min at 37 deg C; released p-nitrophenol det. spectrophotometrically at 405 nm

Citation

Shinde, Jayantrao; Taldone, Tony; Barletta, Michael; Kunaparaju, Naveen; Hu, Bo; Kumar, Sunil; Placido, Jessica; Zito, S. William

Carbohydrate Research, 2008 , vol. 343, # 7 p. 1278 - 1281 Title/Abstract Full Text View citing articles Show Details

Effect

Genotoxic

Biological material

VERO

Assay Description

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Results

score: 70-78, control: 10, reference: 153-198

Citation

Savi, Luciane A.; Leal, Paulo C.; Vieira, Tiago O.; Rosso, Rober; Nunes, Ricardo J.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.; Barardi, Celia R. M.; Simoes, Claudia Maria Oliveira

Arzneimittel-Forschung/Drug Research, 2005 , vol. 55, # 1 p. 66 - 75 Title/Abstract Full Text View citing articles Show Details

Effect

Antiproliferative

Assay Description

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Bioassay : control: MEM (minimum essential medium); reference: H2O2, 100 and 200 μmol/l confluent cells incubated with 2 non-cytotoxic but antiherpetic conc.-s of title comp. at 37 deg C in humidified 5 percent CO2 atmosphere for 90 min in MEM; cellular DNA damage assessed by the Comet assay, scores: 0 (all undamaged) to 200 (all max. damaged)

Target : Spodoptera frugiperda larvae Bioassay : reference: commercial extract of neem larval weigth lost control: 100 antifeedant activity bioassay

Results

larval weight lost: 23, reference: 2.5

Citation

Urrea-Bulla; Suarez M; Moreno-Murillo

Fitoterapia, 2004 , vol. 75, # 3-4 p. 392 - 394 Title/Abstract Full Text View citing articles Show Details

Biological material

RAW 264.7 cell line

Assay Description

Effect : gene expression; effect on Bioassay : gene expression of inducible nitric oxide synthase (iNOS), cytokines interleukin (IL)-1, IL-10, IL-12, IL-18, TNF-α and interferon (IFN)-γ was investigated by reverse-transcription polymerase chain reaction


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Results

low and transient levels of TNFα and IL-10 were induced

Citation

Radtke, Oliver A.; Kiderlen, Albrecht F.; Kayser, Oliver; Kolodziej, Herbert

Planta Medica, 2004 , vol. 70, # 10 p. 924 - 928 Title/Abstract Full Text View citing articles Show Details

Biological material

RAW 264.7 cell line

Assay Description

Effect : gene expression; effect on Bioassay : Leishmania major-infected cells; gene expression of inducible nitric oxide synthase (iNOS), cytokines interleukin (IL)-1, IL-10, IL-12, IL-18, TNF-α and interferon (IFN)-γ was investigated by reverse-transcription polymerase chain reaction

Results

title comp. enhanced and prolonged iNOS and cytokine mRNA expressions; production of IFN-γ mRNA was stimulated

Citation

Radtke, Oliver A.; Kiderlen, Albrecht F.; Kayser, Oliver; Kolodziej, Herbert

Planta Medica, 2004 , vol. 70, # 10 p. 924 - 928 Title/Abstract Full Text View citing articles Show Details

Effect

Antiproliferative

Assay Description

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Target : embryo 3T3-L1 pre-adipocytes BCRC 60159 Bioassay : cultured with title comp. for 24, 48, and 72 h at 37 deg C; cell population growth determined by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide colorimetric assay

Results

title comp. showed conc.- and time-dependent inhibition of cell population growth of cells; fig.

Citation

Hsu, Chin-Lin; Lo, Wen-Hsieh; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7359 - 7365 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

Effect : DPPH radical scavenging Bioassay : 2,2-diphenyl-1-picrylhydrazyl DPPH: 2,2-diphenyl-1-picrylhydrazyl; DPPH method

Results

activity rate ~ 70 percent

Citation

Naz, Shahina; Siddiqi, Rahmanullah; Saeed, Syed Muhammad Ghufran; Sayeed, Syed Asad

Pakistan Journal of Scientific and Industrial Research, 2012 , vol. 55, # 1 p. 14 - 20 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus platelet-rich plasma cell

Assay Description

Effect : ADP-induced platelet aggregation Species : Sprague-Dawley rat platelet poor plasma-adjusted test system used; ADP: adenosine 5'-diphosphate

Citation

Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook

Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus platelet-rich plasma cell

Assay Description

Effect : collagen-induced platelet aggregation Species : Sprague-Dawley rat platelet poor plasma-adjusted test system used

Citation

Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook

Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details


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Biological material

Rattus norvegicus platelet-rich plasma cell

Assay Description

Effect : sodium arachidonate-induced platelet aggregation Species : Sprague-Dawley rat platelet poor plasma-adjusted test system used

Citation

Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook

Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : blood coagulation Bioassay : plasma control values: 12.9 s (PT), 18.8 s (TT), 32.3 s (aPTT)

Results

PT prothrombin time 13.2 s

Citation

Koo, Yean Kyoung; Kim, Jeong Mi; Koo, Ja Yong; Kang, Sam Sik; Bae, KiHwan; Kim, Yeong Shik; Chung, Jin-Ho; Yun-Choi, Hye Sook

Pharmazie, 2010 , vol. 65, # 8 p. 624 - 628 Title/Abstract Full Text View citing articles Show Details

Effect

Immunostimulant

Assay Description

Effect : NO production Bioassay : murine macrophage-like RAW 246.7 cells

Results

NO concentration at 250 μmol/l 7 μmol/l

Citation

Kolodziej, Herbert; Radtke, Oliver A.; Kiderlen, Albrecht F.

Phytochemistry, 2008 , vol. 69, # 18 p. 3103 - 3110 Title/Abstract Full Text View citing articles Show Details

Effect

Immunostimulant

Assay Description

Effect : NO production Target : infected with Leishmania amastigotes Bioassay : murine macrophage-like RAW 246.7 cells

Results

NO concentration ~ 30 μmol/l

Citation

Kolodziej, Herbert; Radtke, Oliver A.; Kiderlen, Albrecht F.

Phytochemistry, 2008 , vol. 69, # 18 p. 3103 - 3110 Title/Abstract Full Text View citing articles Show Details

Effect

Anti-Leishmaniasis

Assay Description

Effect : antileishmanial Target : infected with Leishmania amastigotes Bioassay : murine macrophage-like RAW 246.7 cells

Results

reduction in intracellular parasite survival 50 percent

Citation

Kolodziej, Herbert; Radtke, Oliver A.; Kiderlen, Albrecht F.

Phytochemistry, 2008 , vol. 69, # 18 p. 3103 - 3110 Title/Abstract Full Text View citing articles Show Details

Biological material

human K-562 cell line


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Assay Description

Tail extent moment was determined in human K562 cells after exposition to 800 ug/ml of compound for 24 h by Comet assay

Results

TEM not calculated

Citation

Abdelwahed, Afef; Bouhlel, Ines; Skandrani, Ines; Valenti, Kita; Kadri, Malika; Guiraud, Pascal; Steiman, Regine; Mariotte, Anne-Marie; Ghedira, Kamel; Laporte, Francois; DijouxFranca, Marie-Genevieve; Chekir-Ghedira, Leila

Chemico-Biological Interactions, 2007 , vol. 165, # 1 p. 1 - 13 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicusliver

Assay Description

Inhibitory effects on lipid peroxidation in rat liver microsome; Significant inhibitory effect

Citation

TAKUO OKUDA; TAKASHI YOSHIDA; TSUTOMU HATANO

Journal of natural products, 1989 , vol. 52, # 1 p. 1 - 31 Title/Abstract Full Text Show Details

Biological material

Tobacco budworm larva

Assay Description

Inhibition of tobacco budworm larval growth; ED50 determined as of diet

Citation

Nicollier,G.; Thompson,A.C.

J. Nat. Prod., 1983 , vol. 46, p. 112 Title/Abstract Full Text Show Details

Assay Description

Compound useful in the teratment of diabetes

Citation

G. Zareba; N. Serradell; R. Castaner; S.L. Davies; J. Prous; N. Mealy

Drugs of the future, 2005 , vol. 30, # 12 p. 1253 - 1282 Title/Abstract Full Text Show Details

Biological material

Rattus norvegicus L6

Assay Description

Selectivity of the compound towards inhibitory concentration against rat skeletal L6 cells to that of inhibitory concentration against Trypanosoma brucei rhodesiense STIB 900

Citation

Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J.; Tosun, Fatma; Rueedi, Peter

Antimicrobial Agents and Chemotherapy, 2006 , vol. 50, # 4 p. 1352 - 1364 Title/Abstract Full Text View citing articles Show Details

Target

Cystic fibrosis transmembrane conductance regulator:Wild

Assay Description

Ability to modulate the extracellular transport of thiol containing compound by increasing the activity of cystic fibrosis transmembrane conductance regulator

Citation

Day, Brian J.; Velsor, Leonard W.

Patent: US2004/87527 A1, 2004 ; Title/Abstract Full Text Show Details

Target

Polyphenol Oxidase D [peach]:Wild

Biological material

peach VAR. CORTEZ

Assay Description

Specific activity towards Prunus persica var. Cortez Polyphenol oxidase D at 30 degree C with 9.3 mM compound in 0.1 M citrate-0.2 M phosphate buffer, pH 6.8

Results

Specific activity not calculated

Citation

THOMAS C. WONG; BOR S. LUH; JOHN R. WHITAKER

Plant physiology, 1971 , vol. 48, # 1 p. 19 - 23 Title/Abstract Full Text Show Details


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Target

Polyphenol Oxidase C [peach]:Wild

Biological material

peach VAR. CORTEZ

Assay Description

Specific activity towards Prunus persica var. Cortez Polyphenol oxidase C at 30 degree C with 9.3 mM compound in 0.1 M citrate-0.2 M phosphate buffer, pH 6.8

Results

Specific activity not calculated

Citation

THOMAS C. WONG; BOR S. LUH; JOHN R. WHITAKER

Plant physiology, 1971 , vol. 48, # 1 p. 19 - 23 Title/Abstract Full Text Show Details

Target

Polyphenol Oxidase B [peach]:Wild

Biological material

peach VAR. CORTEZ

Assay Description

Specific activity towards Prunus persica var. Cortez Polyphenol oxidase B at 30 degree C with 9.3 mM compound in 0.1 M citrate-0.2 M phosphate buffer, pH 6.8

Results

Specific activity not calculated

Citation

THOMAS C. WONG; BOR S. LUH; JOHN R. WHITAKER

Plant physiology, 1971 , vol. 48, # 1 p. 19 - 23 Title/Abstract Full Text Show Details

Target

Polyphenol Oxidase A [peach]:Wild

Biological material

peach VAR. CORTEZ

Assay Description

Specific activity towards Prunus persica var. Cortez Polyphenol oxidase A at 30 degree C with 9.3 mM compound in 0.1 M citrate-0.2 M phosphate buffer, pH 6.8

Results

Specific activity not calculated

Citation

THOMAS C. WONG; BOR S. LUH; JOHN R. WHITAKER

Plant physiology, 1971 , vol. 48, # 1 p. 19 - 23 Title/Abstract Full Text Show Details

Assay Description

Inhibitory concetration against NO released by morpholino sydononimine

Results

NT = not tested

Citation

Yanovsky, Inessa; Finkin-Groner, Efrat; Zaikin, Andrey; Lerman, Lena; Shalom, Hila; Zeeli, Shani; Weill, Tehilla; Ginsburg, Isaac; Nudelman, Abraham; Weinstock, Marta

Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10700 - 10715 Title/Abstract Full Text View citing articles Show Details

Effect

scavenging

Assay Description

Oxygen radical absorbance capacity of the compound in relative to 1 uM Trolox equivalent

Results

OXYGEN RADICAL ABSORBANCE CAPACITY not calculated

Citation

Sudjaroen, Yuttana; Hull, William E.; Erben, Gerhard; Würtele, Gerd; Changbumrung, Supranee; Ulrich, Cornelia M.; Owen, Robert W.

Phytochemistry, 2012 , vol. 77, p. 226 - 237 Title/Abstract Full Text View citing articles Show Details

Target

glucose oxidase:Wild


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Assay Description

Inhibitory concentration of the compound against glucose oxidase

Results

NT = not tested

Citation

Yanovsky, Inessa; Finkin-Groner, Efrat; Zaikin, Andrey; Lerman, Lena; Shalom, Hila; Zeeli, Shani; Weill, Tehilla; Ginsburg, Isaac; Nudelman, Abraham; Weinstock, Marta

Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10700 - 10715 Title/Abstract Full Text View citing articles Show Details

Effect

radical scavenging

Assay Description

Effective concentration of the compound required for scavenging of free radical DPPH upon incubation for 15 minutes at RT was determined

Citation

Chapado, Laura; Linares-Palomino, Pablo J.; Salido, Sofia; Altarejos, Joaquin; Rosado, Juan A.; Salido, Gines M.

Bioorganic Chemistry, 2010 , vol. 38, # 3 p. 108 - 114 Title/Abstract Full Text View citing articles Show Details

Target

Sulfotransferase [zebra fish]:Wild

Biological material

zebra fish

Assay Description

Specific activity of compound against recombinant zebrafish SULT2 cytosolic Sulphotransferase using 14uM [35S]PAPS as radioligand in 25ul of 50 mM potassium phosphate buffer, pH 7.0 upon incubation for 2 min at 100 degree C

Results

Specific activity not calculated

Citation

Sugahara, Takuya; Yang, Yuh-Shyong; Liu, Chau-Ching; Pai, T. Govind; Liu, Ming-Cheh

Biochemical Journal, 2003 , vol. 375, # 3 p. 785 - 791 Title/Abstract Full Text View citing articles Show Details

Target

Reverse transcriptase [Human immunodeficiency virus 1]:Mutated

Substance action on target

Inhibitor

Biological material

Human immunodeficiency virus 1

Assay Description

Inhibitory concentration against A17 double mutant (K103N Y181C) HIV-1 reverse transcriptase (90 nM) polymerization using [3H]dGTP (20 uM) as radioligand and poly rC/dG12-18 as template primer upon incubation for 15 min at 37 degree C, pH 7.6

Results

ND

Citation

Tillekeratne; Sherette; Grossman; Hupe; Hudson

Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 20 p. 2763 - 2767 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect of collagen cross-linking by hydro thermal shrinkage temperature was determined in skin collagen matrices with compound dissolved in glycerol upon incubation for 48 h

Results

Shrinkage temperatur not calculated

Citation

Halkes, S Bart A; Vrasidas, Ioannis; Rooijer, Gilbert R; van den Berg, Albert J J; Liskamp, Rob M J; Pieters, Roland J

Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 12 p. 1567 - 1570 Title/Abstract Full Text Show Details

Effect

Antineoplastic

Biological material

U-251MG cell line

Assay Description

Inhibitory concentration of the compound against growth of human U251n cell line


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Results

ND = Not determined

Citation

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

Target

Carbonic anhydrase 2 [human]:Wild

Biological material

human

Assay Description

In vitro binding affinity of the compound towards Human Carbonic anhydrase 2 using 4-nitrophenylacetate as substrate

Results

Competitive

Citation

Guelcin, Ilhami; Beydemir, Suekrue

Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 408 - 430 Title/Abstract Full Text View citing articles Show Details

Target

Carbonic anhydrase 1 [human]:Wild

Biological material

human

Assay Description

In vitro binding affinity of the compound towards Human Carbonic anhydrase 1 using 4-nitrophenylacetate as substrate

Results

Competitive

Citation

Guelcin, Ilhami; Beydemir, Suekrue

Mini-Reviews in Medicinal Chemistry, 2013 , vol. 13, # 3 p. 408 - 430 Title/Abstract Full Text View citing articles Show Details

Effect

Antineoplastic

Biological material

U-87

Assay Description

Inhibitory concentration of the compound against growth of human U-87 cell line

Results

ND = Not determined

Citation

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

Substance action on target

Inhibitor

Biological material

KB

Assay Description

Inhibitory concentration of the compound against growth of human KB cell line

Results

ND = Not determined

Citation

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

Substance action on target

Inhibitor

Biological material

Huh-7 cell line


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Assay Description

Inhibitory concentration of the compound against growth of human Huh-7 cell line

Results

ND = Not determined

Citation

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

Target

72kDa type IV collagenase:Wild

Assay Description

Ligand efficiency of the compound against MATRIX METALLOPROTEINASE 2 was determined

Results

LIGAND EFFICIENCY not calculated

Citation

Rubino, Maria Teresa; Maggi, Dariana; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo

Archiv der Pharmazie, 2011 , vol. 344, # 9 p. 557 - 563 Title/Abstract Full Text View citing articles Show Details

Assay Description

Antioxidant activity of the compound against meadowsweet extract upon incubation in 70% Ethanol in Relation to Oxygen Electroreduction

Results

Antioxidant acitivity not calculated

Citation

Shilova; Semenov; Suslov; Korotkova; Vtorushina; Belyakova

Pharmaceutical Chemistry Journal, 2009 , vol. 43, # 4 p. 185 - 190 Title/Abstract Full Text View citing articles Show Details

Effect

scavenging

Assay Description

Inhibitory concentration of the compound against DPPH radical scavenging upon incubation for 20 mins at RT in the dark

Citation

Das, Sreeparna; Mitra, Indrani; Batuta, Shaikh; Niharul Alam, Md.; Roy, Kunal; Begum, Naznin Ara

Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 21 p. 5050 - 5054 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Citation

BAYLOR COLLEGE OF MEDICINE; Chen, Changyi; Lu, Jian-Ming; Yao, Qizhi

Patent: US2014/163045 A1, 2014 ; Title/Abstract Full Text Show Details

Effect

Antioxidant

Citation

Mohammed, Aminu; Koorbanally, Neil Anthony; Islam, Md. Shahidul

Acta Poloniae Pharmaceutica - Drug Research, 2015 , vol. 72, # 6 p. 1201 - 1215 Title/Abstract Full Text View citing articles Show Details

Biological material

chicken

Citation

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Effect

Phagocytic

Biological material

Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028


Citation

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

In vivo: Animal Model (453) Quantitative Results pX

Parameter

Value (qual)

Value (quant)

Unit

Action on Target

Animal Model

Biological Species

Route of administration

Dose

Concentration

16.68

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Dosing regimen

Effect

Reference (expand all/collapse all)

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

18.48

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

19.87

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

26.43

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

23.45

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

16.47

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

12.12

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

14.1

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details


Concentration

16.39

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

14.1

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

42.21

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

49.81

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

34.83

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

56.97

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

34.49

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

47.76

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

33.18

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

51

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details


Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

32.51

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

47.52

mmol/mg

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

pX

Parameter Concentration

Value (qual)

Value (quant)

Unit

26.54

mmol/mg

Action on Target

Animal Model

Biological Species

Route of administration

Dose

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Dosing regimen

Effect

Reference (expand all/collapse all)

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

43.12

mmol/mg

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

44.59

mmol/mg

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

53.86

mmol/mg

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

27.25

mmol/mg

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.59

mmol/mg

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details


Concentration

0.56

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.67

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.6

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.57

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.52

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.47

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.49

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.75

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

0.66

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

44.84

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details


Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

54.26

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

49.52

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

40.79

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Concentration

50.89

mmol/mg

Rattus norvegicus

intragastric administration

50 mg/kg

Investigational New Drug...

Title/Abstract Full Text View citing articles Show Details

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

NOAEC

5000

mg/kg

Mus musculus

oral administration

5000 mg/kg

Toxic : Acute

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Rajalakshmi; Devaraj; Niranjali Devaraj

Food and Chemical Toxicology, 2001 , vol. 39, # 9 p. 919 - 922 Title/Abstract Full Text View citing articles Show Details

TGI %

16 - 35

%

Mus musculus

intraperitoneal administration

20 mg/kg

Antineoplastic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bin-Chuan; Hsu, Wu-Huei; Yang, Jai-Sing; Hsia, Te-Chun; Lu, Chi-Cheng; Chiang, Jo-Hua; Yang, Jiun-Long; Lin, Ching-Hsiung; Jen-jyh; Lee-jen, Wu Suen; Wellington, Gibson Wood; Chung, Jing-Gung

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 16 p. 7596 - 7604 Title/Abstract Full Text View citing articles Show Details

Length

=

89.9

mm

Rattus norvegicus

oral administration

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Sugimoto, Sachiko; Chi, Guihua; Kato, Yasuyo; Nakamura, Seikou; Matsuda, Hisashi; Yoshikawa, Masayuki

Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 3 p. 269 - 275 Title/Abstract Full Text View citing articles Show Details

T/C (%)

=

139

%

Mus musculus

intraperitoneal administration

Cancer Research, 1979 , ...

Title/Abstract Full Text Show Details

Mus musculus

intraperitoneal administration

Cancer Research, 1979 , ...

Title/Abstract Full Text Show Details

Mus musculus

intraperitoneal

Cancer Research, 1979 , ...

Elford; Wampler; Van 'T Riet

Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details

Dose

=

1500

mg/kg

Elford; Wampler; Van 'T Riet

Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details

Dose

=

7.8

mmol/kg


administration

Title/Abstract Full Text Show Details

Elford; Wampler; Van 'T Riet

Cancer Research, 1979 , vol. 39, # 3 p. 844 - 851 Title/Abstract Full Text Show Details

Mus musculus

intraperitoneal administration

Current Medicinal Chemis...

Title/Abstract Full Text View citing articles Show Details

Lamoral-Theys; Pottier; Dufrasne; Neve; Dubois; Kornienko; Kiss; Ingrassia

Current Medicinal Chemistry, 2010 , vol. 17, # 9 p. 812 - 825 Title/Abstract Full Text View citing articles Show Details

% Inhibition

31

%

experimental ear inflammation

Mus musculus

topical administration

1 mg

Single

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

% Decrease

Active

experimental metabolic disorder

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

50 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

50 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

50 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% Decrease

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% Decrease

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% Decrease

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% Decrease

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% Decrease

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% Decrease

Active

experimental metabolic disorder


Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% Decrease

Active

experimental metabolic disorder

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details


% increase

Active

experimental metabolic disorder

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

C57BL 6 mouse

oral administration

100 mg/kg

Anti-Metabolic disorder

Patent: US2015/174087 ...

Title/Abstract Full Text Show Details

stroke prone spontaneously hypertensive rat

oral administration

40 mg/kg bw

Antihypertensive

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% Decrease

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% increase

Active

experimental metabolic disorder

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

% decrease

87.2

%

experimental hypertension

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

% decrease

78.4

%

experimental hypertension

stroke prone spontaneously hypertensive rat

oral administration

40 mg/kg bw

Antihypertensive

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

3

% Inhibition

Active

zebra fish

1 mM

Anti-Melanogenesis

Patent: WO2016/14529 A...

Title/Abstract Full Text Show Details

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

WISYS TECHNOLOGY FOUNDATION, INC.; HUANG, Cheng-Chen; MONTE, Aaron P.

Patent: WO2016/14529 A1, 2016 ; Title/Abstract Full Text Show Details

Amount increase

Active

streptozotocininduced diabetes


mellitus

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah


European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

% increase

Not active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details


1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

1

Amount increase

Not active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details


Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount increase

Active

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

138.4

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

104.8

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

91.9

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

124.2

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

104.3

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

98.2

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

123.2

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

129.5

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details


Concentration

279.5

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

221.6

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

152.6

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

124.5

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

112.2

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

118.3

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

16.2

μU/ml

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

16.1

μU/ml

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

84.6

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

78.6

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details


Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

92.4

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

86.9

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

HOMA

4.8

no unit

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

HOMA

5.1

no unit

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

21.8

μU/ml

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

16.4

μU/ml

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

114.6

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

78.8

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

171.4

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216


Title/Abstract Full Text View citing articles Show Details

Concentration

91.2

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

HOMA

15.1

no unit

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

HOMA

5.1

no unit

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

116.6

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

189.2

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

142.5

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

208.6

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

291.4

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

216.3

mg/dl

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

191.5

mg/dl

streptozotocin-

Wistar rat

intragastric

20

Repeated

Antidiabetic

European Journal of Phar...


induced diabetes mellitus

administration

mg/kg

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Concentration

134.2

mg/dl

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount

7.4

U/mg protein

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount

0.2

U/mg protein

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount

0.4

U/mg protein

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount

23.2

mg/g tissue

Wistar rat

intragastric administration

20 mg/kg

Repeated

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount

7.2

U/mg protein

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount

0.2

U/mg protein

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount

0.4

U/mg protein

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Amount

21.4

mg/g tissue

streptozotocininduced diabetes mellitus

Wistar rat

intragastric administration

20 mg/kg

Repeated

Antidiabetic

European Journal of Phar...

Title/Abstract Full Text View citing articles Show Details


Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

5.7

% decrease

Active

chicken

2 - 14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.22

% increase

Active

chicken

6 - 14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.22

% increase

Active

chicken

6 - 14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.22

% decrease

Active

chicken

6 - 10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Fold-decrease

2

no unit

chicken

14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.7

% Inhibition

Active

chicken

2 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.22

% Inhibition

Active

chicken

6 - 14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.7

% decrease

Active

chicken

2 - 14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.7

% decrease

Active

chicken

2 - 14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details


Amount

0.05 - 0.118

nmol/μl

chicken

2 - 14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

0.1

mM

chicken

6 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

0.34

mM

chicken

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

0.44

mM

chicken

14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

190

mU/ml

chicken

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

310

mU/ml

chicken

6 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

420

mU/ml

chicken

2 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

87

mU/ml

chicken

14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

10

μmol/mg protein

chicken

14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

17

μmol/mg protein

chicken

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details


Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

27

μmol/mg protein

chicken

2 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

4.2

μmol/mg protein

chicken

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

4.55

μmol/mg protein

chicken

14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

455

pg/ml

chicken

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Amount

795

pg/ml

chicken

14 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

100

%

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

% decrease

Low

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

3.23

% Increase

Active

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

fold

2.07

no unit

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93


Title/Abstract Full Text View citing articles Show Details

3.23

% Increase

Active

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

Mortality rate

60

%

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

Mortality rate

80

%

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

% decrease

3.96

%

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

% decrease

3.25

%

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

% decrease

3.96

%

experimental infection

Institute for Cancer Research mouse

oral administration

100 μg/ml

Antibiotic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

% Decrease

Active

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

% Increase

Active

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Concentration

118.83

mg/dl

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Amount

6.5

%

nicotinamide-

albino rat

oral

20

Repeated

Antineurodegenerative

Metabolic Brain Disease,...


streptozotocin induced diabetes mellitus

administration

mg/kg

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Amount

17.81

μIU/ml

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

HOMA-IR

5.15

no unit

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Amount

44.03

pg/ml

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Amount

0.01619

K

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Amount

0.6576

mU

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Amount

1.1556

U

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Lipid peroxidation

0.1212

nmol

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Concentration

0.1417

nmol

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Amount

0.8202

nmol

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details


Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Amount

9.53

U/g

nicotinamidestreptozotocin induced diabetes mellitus

albino rat

oral administration

20 mg/kg

Repeated

Antineurodegenerative

Metabolic Brain Disease,...

Title/Abstract Full Text View citing articles Show Details

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

1

% reduction

Not active

lipopolysaccharideinduced endotoxemia

C57BL 6 mouse

intraperitoneal administration

20 mg/kg bw

Repeated

Protective

Patent: WO2017/66965 A...

Title/Abstract Full Text Show Details

lipopolysaccharideinduced endotoxemia

C57BL 6 mouse

Antiinflammatory

Patent: WO2017/66965 A...

Title/Abstract Full Text Show Details

lipopolysaccharideinduced endotoxemia

C57BL 6 mouse

Antiinflammatory

Patent: WO2017/66965 A...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

THE UNIVERSITY OF HONG KONG; RONG, Jianhui

Patent: WO2017/66965 A1, 2017 ; Title/Abstract Full Text Show Details

1

% decrease

Not active

THE UNIVERSITY OF HONG KONG; RONG, Jianhui

Patent: WO2017/66965 A1, 2017 ; Title/Abstract Full Text Show Details

1

% decrease

Not active

THE UNIVERSITY OF HONG KONG; RONG, Jianhui

Patent: WO2017/66965 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

145

g/l

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

count

1200000000

cell/l

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

137

g/l

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

count

1200000000

cell/l

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Pressure

71

mmHg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Amount

0.12

l/min/kg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details


SVRI

1673

dyn*s*cm5

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Pressure

11.6

mmHg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

heart rate

125

no unit

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Pressure

60

mmHg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Amount

0.13

l/min/kg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

SVRI

1478

dyn*s*cm5

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Pressure

11.3

mmHg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

heart rate

127

no unit

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

% Increase

Active

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

% Increase

Active

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

1

% change

Not active


UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

pX

Parameter

Value (qual)

% Change

Low

Value (quant)

Unit

Action on Target

Animal Model

Biological Species

Route of administration

Dose

Dosing regimen

Effect

Reference (expand all/collapse all)

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

% decrease

Active

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Pressure

22

mmHg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Pressure

53

mmHg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

pH

7.17

no unit

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Pressure

23

mmHg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Pressure

54

mmHg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

pH

7.12

no unit

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

% decrease

Active

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

1

% Increase

Not active


UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

0.75

nmol/l

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

0.8

mmol/l

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

41

ng/l

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

344

IU

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

4573

IU

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

8.1

mmol/l

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Creatinine clearance

30

ml/min

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Amount

5.5

no unit

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

407

IU

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

6273

IU

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details


Concentration

7.5

mmol/l

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Creatinine clearance

24

ml/min

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Amount

6.2

no unit

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

344

IU

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

407

IU

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

315

IU

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

409

IU

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

25

pg/mg

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Amount

2.44

μmol/min/mg protein

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Concentration

69

ng/l

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Amount

22

ml/min/kg


UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Amount

26

ml/min/kg

experimental sepsis

Canine

Patent: US2017/128398 ...

Title/Abstract Full Text Show Details

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

UNIVERSITY OF MANITOBA; Mink, Steven; Fernyhough, Paul

Patent: US2017/128398 A1, 2017 ; Title/Abstract Full Text Show Details

Rate

245.75

bpm

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Rate

241.25

bpm

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

23

ms

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

26.25

ms

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

47.75

ms

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

40.25

ms

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

19.75

ms

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

18

ms

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details


Time

57.25

ms

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

79

ms

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

120.67

ms

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Time

150.33

ms

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

R height

0.22

mV

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

R height

0.24

mV

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

7.28

μmol/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

7.6

μmol/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

15.41

μmol/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

15.38

μmol/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details


Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

0.17

μmol/l

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

0.19

μmol/l

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

8.82

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

8.04

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

15.42

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

15.94

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

0.71

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

0.88

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

0.17

mmol/min/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details


Activity

0.14

mmol/min/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

61.19

μmol/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

61.17

μmol/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

38.43

μmol/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

39.37

μmol/mg protein

Diazinon-induced cardiac oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

64.63

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

64.33

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

33.02

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

33.18

μmol/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

0.194

mmol/min/mg protein

Diazinon-induced renal oxidative

Wistar rat

oral administration

120 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details


stress

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

0.191

mmol/min/mg protein

Diazinon-induced renal oxidative stress

Wistar rat

oral administration

60 mg/kg

Repeated

Antioxidant

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

0.55

unit/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

0.58

unit/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

157.21

unit/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

121.42

unit/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

294.4

unit/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Activity

266.8

unit/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Weight

0.35

g

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Weight

0.41

g

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex


Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Weight

0.77

g

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Weight

0.81

g

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

%

33.24

%

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

%

34.07

%

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

8.11

g/dl

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

10.37

g/dl

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

5010000000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

6840000000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Volume

49.81

fl

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details


Volume

66.35

fl

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

15.16

pg

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

16.19

pg

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

30430000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

24390000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

10530000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Concentration

10190000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

6030000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

6110000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

100000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details


Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

100000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

4220000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

3920000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

100000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

100000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

10000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

60 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

Amount

10000000

cell/l

Diazinon-induced toxicity

Wistar rat

oral administration

120 mg/kg

Repeated

Protective

Interdisciplinary Toxico...

Title/Abstract Full Text View citing articles Show Details

Ajibade, Temitayo Olabisi; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Asenuga, Ebunoluwa Racheal; Afolabi, Jeremiah Moyinoluwa; Adedapo, Adeolu Alex

Interdisciplinary Toxicology, 2016 , vol. 9, # 2 p. 66 - 77 Title/Abstract Full Text View citing articles Show Details

% decrease

Active

experimental candidiasis

Institute for Cancer Research mouse

intraperitoneal administration

Institute for Cancer Research mouse

intraperitoneal administration

20 - 80 mg/kg

Repeated

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

%

0

%

experimental candidiasis

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

80 mg/kg

Repeated

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details


%

33.3

%

experimental candidiasis

Institute for Cancer Research mouse

intraperitoneal administration

Institute for Cancer Research mouse

intraperitoneal administration

Institute for Cancer Research mouse

intraperitoneal administration

Institute for Cancer Research mouse

intraperitoneal administration

Institute for Cancer Research mouse

intraperitoneal administration

Wistar rat

oral administration

20 mg/kg

Repeated

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

%

8.3

%

experimental candidiasis

40 mg/kg

Repeated

Antifungal

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

Weight

24.61

g

experimental candidiasis

80 mg/kg

Repeated

Body Weight

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

Weight

21.76

g

experimental candidiasis

20 mg/kg

Repeated

Body Weight

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

Weight

25.35

g

experimental candidiasis

40 mg/kg

Repeated

Body Weight

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

%

-22.23

%

Nmethylnitrosoureainduced colon cancer

50 mg/kg bw

Repeated

50 mg/kg bw

Repeated

50 mg/kg bw

Repeated

50 mg/kg bw

Repeated

50mg/kg

Repeated

Antineoplastic

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Attia, Naglaa A.; Sayed, Alaa H.; Mahmoud, Nadia S.; Ahmed, Hanaa H.

Medicinal Chemistry Research, 2017 , vol. 26, # 10 p. 2614 - 2623 Title/Abstract Full Text View citing articles Show Details

%

-19.09

%

Nmethylnitrosoureainduced colon cancer

Wistar rat

oral administration

Antineoplastic

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Attia, Naglaa A.; Sayed, Alaa H.; Mahmoud, Nadia S.; Ahmed, Hanaa H.

Medicinal Chemistry Research, 2017 , vol. 26, # 10 p. 2614 - 2623 Title/Abstract Full Text View citing articles Show Details

Concentration

1691.5

pg/ml

Nmethylnitrosoureainduced colon cancer

Wistar rat

oral administration

Antineoplastic

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Attia, Naglaa A.; Sayed, Alaa H.; Mahmoud, Nadia S.; Ahmed, Hanaa H.

Medicinal Chemistry Research, 2017 , vol. 26, # 10 p. 2614 - 2623 Title/Abstract Full Text View citing articles Show Details

Concentration

5.17

ng/ml

Nmethylnitrosoureainduced colon cancer

Wistar rat

oral administration

Antineoplastic

Medicinal Chemistry Rese...

Title/Abstract Full Text View citing articles Show Details

Attia, Naglaa A.; Sayed, Alaa H.; Mahmoud, Nadia S.; Ahmed, Hanaa H.

Medicinal Chemistry Research, 2017 , vol. 26, # 10 p. 2614 - 2623 Title/Abstract Full Text View citing articles Show Details

Fold-increase

4.7

no unit

Wistar rat

oral administration

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details


Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Fold-increase

5.5

no unit

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Fold-increase

5

no unit

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Fold-increase

4.4

no unit

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Fold-increase

5.1

no unit

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Fold-increase

4.9

no unit

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Fold-increase

1.6

no unit

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Papp (transport)

3.5E-06

cm/s

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Papp (transport)

4.1E-06

cm/s

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Papp (transport)

4.4E-06

cm/s

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448


Title/Abstract Full Text View citing articles Show Details

Concentration

11.7

μg/ml

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Concentration

12.7

μg/ml

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

Concentration

13.5

μg/ml

Wistar rat

oral administration

50mg/kg

Repeated

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Athukuri, Bhargavi Latha; Neerati, Prasad

Phytotherapy Research, 2017 , vol. 31, # 9 p. 1441 - 1448 Title/Abstract Full Text View citing articles Show Details

5

% Inhibition

Active

zebra fish

10 μM

Skin whitening

Patent: US2017/342047 ...

Title/Abstract Full Text Show Details

WISYS TECHNOLOGY FOUNDATION, INC.; Huang, Cheng-Chen; Monte, Aaron P.

Patent: US2017/342047 A1, 2017 ; Title/Abstract Full Text Show Details

Qualitative Information 1 of 104

2 of 104

3 of 104

Biological material

goose

Assay Description

Effect : avian influenza; protection from Example 54 Examples 33 to 50 are repeated except that in Example 17 one hundred geese, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the geese, and not the chickens, are utilized.

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Hensley, Charles; Pyo, Sung

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

chicken

Assay Description

Effect : avian influenza; protection from Example 39 Example 33 is repeated except that each ten pounds of primary conventional chicken feed is admixed with two tablespoons of the aqueous medicament composition of Example 7 to produce the resulting medicament composition-primary chicken feed mixture that is administered to the test group. Similar

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Hensley, Charles; Pyo, Sung

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

turkey (bird)

Assay Description

Effect : avian influenza; protection from Example 51 Examples 33 to 50 are repeated except that in Example 17 one hundred turkeys, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the turkeys, and not the chickens, are utilized.

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza


4 of 104

5 of 104

6 of 104

Citation

Hensley, Charles; Pyo, Sung

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

duck

Assay Description

Effect : avian influenza; protection from Example 52 Examples 33 to 50 are repeated except that in Example 33 one hundred ducks, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the ducks, and not the chickens, are utilized.

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Hensley, Charles; Pyo, Sung

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : avian influenza; protection from Species : pheasant Example 53 Examples 33 to 50 are repeated except that in Example 17 one hundred pheasants, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the pheasants, and not the chickens, are utilized.

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Hensley, Charles; Pyo, Sung

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antiallergic

Assay Description

7 of 104

Results

at 0.05/0.13 mg/ear title comp. inhibited oxazolone-induced type IV allergy by 8.3/29.5 percent (vs 73.2/83.8 percent for hydrocortisone)

Citation

Suzuki, Masazumi; Yoshino, Kyoji; Maeda-Yamamoto, Mari; Miyase, Toshio; Sano, Mitsuaki

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 11 p. 5649 - 5653 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Assay Description

8 of 104

Target : ICR mouse Bioassay : 24 h later sacrificed; circular parts of both ears removed and their weights measured; ear swelling ratio determined; hydrocortisone used as reference comp. in vivo; inhibition of oxazoloneinduced type IV allergy examined; 5 mice (4 wks) sensitized by application of 0.5 percent oxazolone solution (OS) to skin of abdominal region; 5 d later challenged by application of OS to both sides of mouse's right ear

Target : senescence accelerated mouse Bioassay : 9-month-old mice were treated; CAT: catalase; GPx: glutathione peroxidase; LPO: lipid peroxidation; MDA: malonaldehyde; TBARS: thiobarbituric acid reactive substances; control: 0.9 percent NaCl mice received title comp.; CAT and GPx activities measured in whole blood and liver spectrophotometrically; LPO measured in liver, brain and kidney using formation of MDA according to presence of TBARS

Results

title comp. increased CAT and GPx activities and reduced extent of lipid peroxidation (diagram)

Citation

Li; Ng; Gao; Fu; Niu; Zhao; Chen; Liu

Life Sciences, 2005 , vol. 77, # 2 p. 230 - 240 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity


Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase

9 of 104

10 of 104

11 of 104

12 of 104

Results

enzyme activity 3.4 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 4.13 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase

Results

enzyme activity 4.46 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 4.31 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant


13 of 104

14 of 104

15 of 104

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase

Results

enzyme activity 3.29 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 5.24 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase

Results

enzyme activity 4.31 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 7.71 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam


Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

16 of 104

17 of 104

18 of 104

19 of 104

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase

Results

enzyme activity 5.47 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

superoxide dismutase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : SOD activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; SOD: superoxide dismutase; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 5.32 u/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

enzyme activity 41.85 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;Caecum


Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

20 of 104

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Results

enzyme activity 36.03 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

enzyme activity 43.72 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 41.58 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

enzyme activity 45.58 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details


23 of 104

24 of 104

25 of 104

26 of 104

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 44.06 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

enzyme activity 51.52 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 37.22 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

enzyme activity 40.96 μmol H2O2 utilized/min/mg protein


27 of 104

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Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Target

catalase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Catalase activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 35.28 μmol H2O2 utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione

Results

enzyme activity 4.28 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 4.2 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione

Results

enzyme activity 4.27 mmol GSH utilized/min/mg protein


31 of 104

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34 of 104

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 3.39 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione

Results

enzyme activity 5.46 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 3.17 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione

Results

enzyme activity 7.69 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details


35 of 104

36 of 104

37 of 104

38 of 104

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 7.7 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione

Results

enzyme activity 5.53 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione peroxidase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione peroxidase activity enzyme activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; GSH: reduced glutathione; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 5.51 mmol GSH utilized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;

Results

enzyme activity 10.96 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details


39 of 104

40 of 104

41 of 104

42 of 104

43 of 104

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 6.97 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;

Results

enzyme activity 12.04 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 11.54 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;

Results

enzyme activity 11.64 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus


44 of 104

45 of 104

46 of 104

47 of 104

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 11.04 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;

Results

enzyme activity 21.26 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

enzyme activity 18.9 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil;

Results

enzyme activity 12.36 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Target

Glutathione reductase:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : Glutathione reductase activity enzyme activity Target : ;proximal colon


Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

48 of 104

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52 of 104

Results

enzyme activity 12.06 mmol NADPH oxidized/min/mg protein

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 1.58 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 1.61 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 1.92 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 2.01 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus


53 of 104

54 of 104

55 of 104

56 of 104

Assay Description

Effect : Vitamin C level Target : Vitamin C ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 1.58 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 2.15 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 1.95 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 1.93 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 1.72 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details


57 of 104

58 of 104

59 of 104

60 of 104

61 of 104

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin C level Target : Vitamin C ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 2.11 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 0.78 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;Caecum Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 0.81 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 0.94 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;distal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 1.52 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259


Title/Abstract Full Text View citing articles Show Details

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Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 0.82 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;intestine Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 0.88 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 1.44 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;liver Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 0.98 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil

Results

concentration 0.86 mg/100 g tissue


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Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : Vitamin E level Target : Vitamin E ;proximal colon Species : albino Wistar rat animals given pellet diet containing 4.2% fat and 15.8% peanut oil; DMH: 1,2-dimethyhydrazine

Results

concentration 1.92 mg/100 g tissue

Citation

Giftson, Jebakkan Senapathy; Jayanthi, Sathiavelu; Nalini, Namasivayam

Investigational New Drugs, 2010 , vol. 28, # 3 p. 251 - 259 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : |biotransformation Target : Wister rats Bioassay : metabolite levels in serum and urinary excretion determined 3-6 rats (4 weeks, 259-304 g)/group kept in air conditioned room (23 deg C, 50-66 percent humidity, 12 h light/dark cycle) with free access to food and water; blood and urine collected at predetermined times

Citation

Nakamura, Yumiko; Tonogai, Yasuhide

Journal of Agricultural and Food Chemistry, 2003 , vol. 51, # 24 p. 7215 - 7225 Title/Abstract Full Text View citing articles Show Details

Assay Description

Effect : avian influenza; protection from Target : pheasant Bioassay : Example 53 Examples 33 to 50 are repeated except that in Example 17 one hundred pheasants, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the pheasants, and not the chickens, are utilized.

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Sung, Pyo; Charles, Hensley

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

goose

Assay Description

Effect : avian influenza; protection from Bioassay : Example 54 Examples 33 to 50 are repeated except that in Example 17 one hundred geese, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the geese, and not the chickens, are utilized.

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Sung, Pyo; Charles, Hensley

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

chicken

Assay Description

Effect : avian influenza; protection from Bioassay : Example 39 Example 33 is repeated except that each ten pounds of primary conventional chicken feed is admixed with two tablespoons of the aqueous medicament composition of Example 7 to produce the resulting medicament composition-primary chicken feed mixture that is administered to the test group. Similar

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Sung, Pyo; Charles, Hensley

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details


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Biological material

turkey (bird)

Assay Description

Effect : avian influenza; protection from Bioassay : Example 51 Examples 33 to 50 are repeated except that in Example 17 one hundred turkeys, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the turkeys, and not the chickens, are utilized.

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Sung, Pyo; Charles, Hensley

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

duck

Assay Description

Effect : avian influenza; protection from Bioassay : Example 52 Examples 33 to 50 are repeated except that in Example 33 one hundred ducks, and not one hundred chickens, are provided. Similar results are obtained in each Example 33 to 50 when the ducks, and not the chickens, are utilized.

Results

treatment with ~0.1-30 g of the 2.0-50weight% aqueous title compound medicament composition showed that none of the chickens in the test group contracted avian influenza

Citation

Sung, Pyo; Charles, Hensley

Patent: US2008/75795 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : |pharmacokinetics Bioassay : in situ gastric absorption tested anesthetized rats starved for 5-8 h; pylorus ligated; portal vein and abdominal aorta blood withdrawn at 5, 15, and 25 min post dosing; total, intact, and conjugated title comp. levels in plasma determined by HPLC-ECD method

Results

at 5 min after administration, plasma conc. of intact and conjugated title comp. in the portal vein/abdominal artery were 0.45/0.05 and 0.09/0.16 μmol/l, respectively

Citation

Konishi, Yutaka; Zhao, Zhaohui; Shimizu, Makoto

Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 20 p. 7539 - 7543 Title/Abstract Full Text View citing articles Show Details

Effect

Neuroprotective

Biological material

Rattus norvegicus

Assay Description

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Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control rats received title comp. alone or with Fe-NTA injection; 12 h after last treatment, blood sampled; serum levels of creatinine and hydrogen peroxide (H2O2) and level of blood urea nitrogen (BUN) measured

Results

title comp. alone had no effect but significantly and dose-dependently attenuated by 29-35%, 74-88% and 30-40%, resp., Fe-NTA-induced increase in BUN, serum creatinine and H2O2 (table)

Citation

Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat

Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : DNA synthesis; inhibition of Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control rats received title comp. alone or with Fe-NTA; 18 h after Fe-NTA injection, <3H>thymidine injected i.p.; 2 h later, rats sacrificed; kidneys removed; DNA synthesis as <3H>thymidine incorporation into renal DNA determined

Results

title comp. caused significant and dose-dependent reduction (by 42-70%) in Fe-NTA-induced enhancement of DNA synthesis (figure)

Citation

Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat

Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details


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Target

enzyme:Wild

Biological material

Rattus norvegicus

Assay Description

Effect : |enzyme; inhib. of Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control rats received title comp. alone/with Fe-NTA; 12 h after last treatment, rats sacrificed; kidneys removed; homogenized; postmitochondrial supernatant, microsomal fractions prepared; renal ornithine decarboxylase (ODC) activity determined

Results

title comp. alone had no effect but significantly and dose-dependently attenuated by 50-82% at 10-20 mg/kg, resp., Fe-NTA-induced increase in activity of ODC (figure)

Citation

Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat

Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

Rattus norvegicus

Assay Description

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Results

title comp. alone had no effect but significantly and dose-dependently attenuated by 15-31%, 16-33% and 17-45%, resp., Fe-NTA-induced reduction in activities of renal catalase, GPx and G6PD (table)

Citation

Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat

Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

Rattus norvegicus

Assay Description

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Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control; GSH: reduced glutathione; GST: glutathione-S-transferase; GR: glutathione reductase rats received title comp. alone/with Fe-NTA; 12 h after last treatment, rats sacrificed; kidneys removed; homogenized; postmitochondrial supernatant, microsomal fractions prepared; GSH content, activities of GSH metabolizing enzymes (GST, GR) determined

Results

title comp. alone had no effect but significantly and dose-dependently attenuated by 12-28%, 21-36% and 15-40%, resp., Fe-NTA-induced depletion of renal GSH, reduction in activities of GST and GR (table)

Citation

Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat

Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details

Effect

Antioxidant

Biological material

Rattus norvegicus

Assay Description

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Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control; GPx: glutathione peroxidase; G6PD: glucose-6-phosphate dehydrogenase rats received title comp. alone/with Fe-NTA; 12 h after last treatment, rats sacrificed; kidneys removed; ho mogenized; postmitochondrial supernatant and microsomal fractions prepared; renal antioxidant enzymes catalase, GPx and G6PD determined

Bioassay : Fe-NTA: ferric nitrilotriacetic acid (9 mg/kg, single i.p. injection, 1 h after last title comp. dose); vehicle control; QR: quinone reductase; XO: xanthine oxidase; MDA: malondialdehyde; LPO: lipid peroxidation rats received title comp. alone/with Fe-NTA; 12 h after last treatment, rats sacrificed; kidneys removed; postmitochondrial supernatant, microsomal fractions prepared; renal QR, XO and ironascorbate-induced microsomal LPO (as MDA production) determined

Results

title comp. alone had no effect but significantly and dose-dependently attenuated by 56-76 and 50-83%, and 12-34%, resp., Fe-NTA-induced increase in activity of XO and in renal microsomal LPO, and Fe-NTA-induced reduction in activity of QR (table)

Citation

Prasad, Lakshmi; Khan, Tajdar Husain; Jahangir, Tamanna; Sultana, Sarwat

Human and Experimental Toxicology, 2006 , vol. 25, # 9 p. 523 - 529 Title/Abstract Full Text View citing articles Show Details

Biological material

dog


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Assay Description

Effect : adverse events; occurrence of Bioassay : Experimental Example 6: Tests for safety of anhydrous gallic acid on Beagle dogs <n="14"/>[88] Tests were performed to investigate the toxicity to non-rodents, to which the anhydrous gallic acid in Example 3 is orally administered once. Male and female Beagle dogs were used for a test group, to which

Results

temporary vomiting, brownish stool diarrhea and anorexia were observed when title compound was administered

Citation

NA, Chun-Soo; KIM, Sang-Mi; CHOI, Bum-Rak; KIM, Jin-Beom; SEO, Seok-In

Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details

Assay Description

Effect : sexual hormone level; effect on Target : Sprague-Dawley (SD) rat Bioassay : Experimental Example 1: Effect of Lacquer Tree Flavonoids on Increase inSexual Hormones of Rats.[70] In this experiment, Sprague-Dawley rats weighing about 25Og were used as a control group (n=8, a no-administration group) and a test group (n=8, a group administered with the lacquer tree flavonoids

Results

title compound administration at 100 mg/kg dose caused a 2.5 fold or more increase in testosterone level; figure is given

Citation

NA, Chun-Soo; KIM, Sang-Mi; CHOI, Bum-Rak; KIM, Jin-Beom; SEO, Seok-In

Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Body Weight

Assay Description

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Citation

NA, Chun-Soo; KIM, Sang-Mi; CHOI, Bum-Rak; KIM, Jin-Beom; SEO, Seok-In

Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Toxic

Biological material

dog

Assay Description

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Bioassay : Experimental Example 6: Tests for safety of anhydrous gallic acid on Beagle dogs <n="14"/>[88] Tests were performed to investigate the toxicity to non-rodents, to which the anhydrous gallic acid in Example 3 is orally administered once. Male and female Beagle dogs were used for a test group, to which

Citation

NA, Chun-Soo; KIM, Sang-Mi; CHOI, Bum-Rak; KIM, Jin-Beom; SEO, Seok-In

Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Toxic : Subacute

Biological material

Mus musculus

Assay Description

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Target : Sprague-Dawley (SD) rat Bioassay : Experimental Example 7: Effects of Anhydrous Gallic Acid Administration onVariation in Body Weight of Male Rats[91] This experiment was performed to confirm whether long term administration of the anhydrous gallic acid obtained in Example 3 affects variation in body weight. Sprague- Dawley rats weighting

Bioassay : control: DMSO 12 mice (6/6 f/m/) 6-8 weeks old; animals were observed twice daily for the subsequent 28 days; then sacrificed following an overnight fast; autopsy was carried out on all animals; whole blood was collected

Results

no effects on body weight and organ weight (except decrease in the spleen weight); slight decrease in food intake; minor differences in hematological or histological examinations; slight but nonsignificant decrease in the hemoglobin level

Citation

Rajalakshmi; Devaraj; Niranjali Devaraj

Food and Chemical Toxicology, 2001 , vol. 39, # 9 p. 919 - 922 Title/Abstract Full Text View citing articles Show Details

Effect

Antineoplastic

Biological material

Mus musculus


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Assay Description

Effect : tumor size Species : BALB/cnu/nu mouse PDP value for tumor growth inhibition measured after treatment of title comp. from 22 to 38 days

Results

tumor weight decrease 40 %

Citation

Bin-Chuan; Hsu, Wu-Huei; Yang, Jai-Sing; Hsia, Te-Chun; Lu, Chi-Cheng; Chiang, Jo-Hua; Yang, Jiun-Long; Lin, Ching-Hsiung; Jen-jyh; Lee-jen, Wu Suen; Wellington, Gibson Wood; Chung, Jing-Gung

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 16 p. 7596 - 7604 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : antihaemorrhoidal Bioassay : Pharmacological Activity Of The Extract Antihaemorrhoidal activity The antihaemorrhoidal activity of the Euphorbia prostrcrta extract was assessed and compared with reference drug, diosmin using anorectum: body weight ratio model in rats (modified method of Jia et al., 2000). Euphorbia prostrata extract

Results

title comp. (1.123 mg/kg, 7 days) showed significant decrease in anorectum : body weight ratio as well as inflammation and redness at the site when compared to control

Citation

PANACEA BOITEC LTD.

Patent: WO2005/65696 A1, 2005 ; Title/Abstract Full Text Show Details

Effect

Body Weight

Biological material

Rattus norvegicus

Assay Description

Effect : body weight; effect on Experimental Example 7: Effects of Anhydrous Gallic Acid Administration onVariation in Body Weight of Male Rats[91] This experiment was performed to confirm whether long term administration of the anhydrous gallic acid obtained in Example 3 affects variation in body weight. Sprague- Dawley rats weighting

Citation

LIFETREE BIOTECH CO., LTD.

Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Toxic

Biological material

dog

Assay Description

Effect : toxic Experimental Example 6: Tests for safety of anhydrous gallic acid on Beagle dogs <n="14"/>[88] Tests were performed to investigate the toxicity to non-rodents, to which the anhydrous gallic acid in Example 3 is orally administered once. Male and female Beagle dogs were used for a test group, to which

Citation

LIFETREE BIOTECH CO., LTD.

Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

dog

Assay Description

Effect : adverse events; occurrence of Experimental Example 6: Tests for safety of anhydrous gallic acid on Beagle dogs <n="14"/>[88] Tests were performed to investigate the toxicity to non-rodents, to which the anhydrous gallic acid in Example 3 is orally administered once. Male and female Beagle dogs were used for a test group, to which

Results

temporary vomiting, brownish stool diarrhea and anorexia were observed when title compound was administered

Citation

LIFETREE BIOTECH CO., LTD.

Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details

Biological material

Rattus norvegicus


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Assay Description

Effect : sexual hormone level; effect on Experimental Example 1: Effect of Lacquer Tree Flavonoids on Increase inSexual Hormones of Rats.[70] In this experiment, Sprague-Dawley rats weighing about 25Og were used as a control group (n=8, a no-administration group) and a test group (n=8, a group administered with the lacquer tree flavonoids

Results

title compound administration at 100 mg/kg dose caused a 2.5 fold or more increase in testosterone level; figure is given

Citation

LIFETREE BIOTECH CO., LTD.

Patent: WO2008/93979 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Toxic : Subchronic

Assay Description

Effect : changes in organs and body weights Target : F344/DuCrj rat Bioassay : control to untreated rats 5 weeks age rats in 5 groups (10 rats of each sex) receive title comp. in diet for 13 weeks; rats observed daily for clinical signs and mortality; body weight and food consumption measured weekly; after 13 week rats sacrificed; organ weights measured

Results

reduction of body weights in male and female (5 percent groups): 16 and 14 percent, resp.; no changes in food consumptions; increase in relative liver and spleen weights in both sexes with 1.7 percent and 5 percent title comp. treatment, respectively;

Citation

Niho; Shibutani; Tamura; Toyoda; Uneyama; Takahashi; Hirose

Food and Chemical Toxicology, 2001 , vol. 39, # 11 p. 1063 - 1070 Title/Abstract Full Text View citing articles Show Details

Effect

Toxic : Subchronic

Assay Description

Effect : changes in parameters of hematology and blood biochemistry Target : F344/DuCrj rat Bioassay : Hb: hemoglobin; Ht: hematocrit; RBC: red blood cells; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; BUN: blood urea nitrogen; CRN: creatinine; ALP: alkaline phosphatase; control to untreated rats 5 weeks age rats in 5 groups (10 rats of each sex) receive title comp. in diet for 13 weeks; after 13 week rats anesthetized, blood sampled from abdominal aorta for hematology and blood biochemistry

Results

in males decrease of Hb, Ht, RBC in 0.6 percent and of RBC, MCV, MCH at 5 percent; in females decrease of MCV, MCH, RBC, Hb, Ht at 5 percent; sign. increase of reticulocytes at 5 percent; increase of BUN, ALP (only males) at 5 percent; decrease of CRN

Citation

Niho; Shibutani; Tamura; Toyoda; Uneyama; Takahashi; Hirose

Food and Chemical Toxicology, 2001 , vol. 39, # 11 p. 1063 - 1070 Title/Abstract Full Text View citing articles Show Details

Effect

Toxic : Subchronic

Assay Description

Effect : changes in parameters of histopathology Target : F344/DuCrj rat Bioassay : control to untreated rats 5 weeks age rats in 5 groups (10 rats of each sex) receive title comp. in diet for 13 weeks; after 13 week rats sacrificed and organs fixed in 10 percent formalin; tissue sections prepared and stained with hematoxilin and eosin in control and 5 percent treated groups

Results

dose-dependent centrilobular liver cell hypertrophy from 1.7 percent; increased incidences of extramedullary hematopoiesis in spleens and deposition of fine-grandular brown pigment in proximal tubular cells in rats of both sexes admin. 5 percent title

Citation

Niho; Shibutani; Tamura; Toyoda; Uneyama; Takahashi; Hirose

Food and Chemical Toxicology, 2001 , vol. 39, # 11 p. 1063 - 1070 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : |metabolic Bioassay : control: hot water instead of black tea intake in vivo; 10 healthy nonsmokers (8 males and 2 females, mean: 61.8 yrs and 28.0 kg/m2); 24-h urine samples collected during last week of 4-week test period; phenolic compounds in samples assessed by GC/MS

Results

only 3 metabolites were present at higher conc. in urine of all 10 subjects during tea-drinking in comparison to water drinking periods

Citation

Hodgson, Jonathan M.; Morton, Lincoln W.; Puddey, Ian B.; Beilin, Lawrence J.; Croft, Kevin D.

Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 6 p. 2276 - 2280 Title/Abstract Full Text View citing articles Show Details


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Biological material

Rattus norvegicus

Assay Description

Effect : |pharmacokinetics Bioassay : gastrointestinal absorption evaluated; 3 rats (6 wks, 170-205 g) fasted for 20 h; blood samples taken at each time point after dosing; serum levels determined by HPLC

Results

Cmax: 0.71 μmol/l; tmax: 60 min; AUC0-1.5 h: 42.6 μmol*min/l; serum conc.-time profiles

Citation

Konishi, Yutaka; Hitomi, Yoshitaka; Yoshioka, Eiji

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 9 p. 2527 - 2532 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : |biotransformation Bioassay : title comp. and its metabolite levels measured by HPLC ex vivo; metabolic fate of title comp. assayed; 6-week-old rats; food and water ad libitum; rats kept at 23 deg C under 12 h light/dark cycle; rats killed; liver removed and homogenized

Results

4-O-methyl gallic acid was detected in liver as metabolite but no title comp.

Citation

Zong, Li; Inoue, Makoto; Nose, Mitsuhiko; Kojima, Keisuke; Sakaguchi, Nahoko; Isuzugawa, Kazuto; Takeda, Tadahiro; Ogihara, Yukio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 3 p. 326 - 329 Title/Abstract Full Text View citing articles Show Details

Biological material

Rattus norvegicus

Assay Description

Effect : |biotransformation Bioassay : urine samples taken at determined times; title comp. and its metabolite levels measured by HPLC; VCI: inferior vena cava in vivo; metabolic fate of title comp. assayed; 6-week-old rats; food and water ad libitum; rats kept at 23 deg C under 12 h light/dark cycle; blood samples from portal vein and VCI collected at determined times

Results

title comp. existed in blood for ca. 6 h and more than half was metabolized to 4-O-methyl gallic acid followed by excretion into urine (metabolism rate 55.3 - 76.5 percent); graphical representation

Citation

Zong, Li; Inoue, Makoto; Nose, Mitsuhiko; Kojima, Keisuke; Sakaguchi, Nahoko; Isuzugawa, Kazuto; Takeda, Tadahiro; Ogihara, Yukio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 3 p. 326 - 329 Title/Abstract Full Text View citing articles Show Details

Effect

Anti-Metabolic disorder

Biological material

C57BL 6 mouse

Citation

Peng, Wen-Huang; Pao, Li-Heng; Chao, Jung; Cheng, Hao-Yuan; Lee, Meng-Shiou

Patent: US2015/174087 A1, 2015 ; Title/Abstract Full Text Show Details

Effect

Antidiabetic

Biological material

Wistar rat

Citation

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Effect

Antidiabetic

Biological material

Wistar rat

Citation

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah


European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

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Effect

Antidiabetic

Biological material

Wistar rat

Citation

Gandhi, Gopalsamy Rajiv; Jothi, Gnanasekaran; Antony, Poovathumkal James; Balakrishna, Kedike; Paulraj, Michael Gabriel; Ignacimuthu, Savarimuthu; Stalin, Antony; Al-Dhabi, Naif Abdullah

European Journal of Pharmacology, 2014 , vol. 745, p. 201 - 216 Title/Abstract Full Text View citing articles Show Details

Biological material

chicken

Citation

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Effect

Antineurodegenerative

Biological material

albino rat

Citation

Abdel-Moneim, Adel; Yousef, Ahmed I.; Abd El-Twab, Sanaa M.; Abdel Reheim, Eman S.; Ashour, Mohamed B.

Metabolic Brain Disease, 2017 , vol. 32, # 4 p. 1279 - 1286 Title/Abstract Full Text View citing articles Show Details

Metabolism (50) Quantitative Results pX

Parameter

1

Foldincrease

Value (qual)

Value (quant)

Unit

Action on Target

NA

Inhibitor

Target

Tissue/Organ

Cell

Multidrug resistance protein 1 [human]:Wild

KB-C2 cell line

Cell fraction

Substrate /Carried Molecule [Rhodamine 123]+ (+)-Daunorubicin Hydrochloride

Dose

Reference (expand all/collapse all)

100 µM

Biochemical Pharmacology...

Title/Abstract Full Text View citing articles Show Details

Kitagawa, Shuji; Nabekura, Tomohiro; Kamiyama, Shizu; Takahashi, Tomoharu; Nakamura, Yutaka; Kashiwada, Yoshiki; Ikeshiro, Yasumasa

Biochemical Pharmacology, 2005 , vol. 70, # 8 p. 1262 - 1266 Title/Abstract Full Text View citing articles Show Details

% Inhibition

<

50

%

Inhibitor

Multidrug resistanceassociated protein 1 [human]:Wild

blood

erythrocyte

2',7'-bis-(3carboxypropyl)-5,6carboxyfluorescein acetoxymethyl ester

0 µM

Oncology Research, 2002 ...

Title/Abstract Full Text View citing articles Show Details

Bobrowska-Haegerstrand, Malgorzata; Wrobel, Anna; Mrowczynska, Lucyna; Soederstroem, Thomas; Shirataki, Yoshiaki; Motohashi, Noboru; Molnar, Joseph; Michalak, Krystyna; Haegerstrand, Henry

Oncology Research, 2002 , vol. 13, # 11 p. 463 - 469 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

Cytochrome P450 1A2 [human]:Wild

Baculovirusinfected insect cell

Microsome

7-Ethoxy-3cyanocoumarin

Xenobiotica, 2012 , vol...

Title/Abstract Full Text View citing articles Show Details

Yang, Li-Ping; Zhou, Zhi-Wei; Chen, Xiao-Wu; Li, Chun Guang; Sneed, Kevin B.; Liang, Jun; Zhou, Shu-Feng

Xenobiotica, 2012 , vol. 42, # 3 p. 238 - 255 Title/Abstract Full Text View citing articles Show Details

1

Foldincrease

NA

Inhibitor

Multidrug resistance protein 1 [human]:Wild

Chieli, Elisabetta; Romiti, Nadia; Rodeiro, Idania; Garrido, Gabino

Food and Chemical Toxicology, 2009 , vol. 47, # 11 p. 2703 - 2710 Title/Abstract Full Text View citing articles Show Details

HK-2

[Rhodamine 123]

0.500000 µM

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details


2.63

% Inhibition

<

30

%

Arylamine Nacetyltransferase 1 [human]:Wild

KMBC cell line

Cytosol

p-Aminobenzoic acid

1000 µM

Xenobiotica, 2006 , vol...

Title/Abstract Full Text View citing articles Show Details

Kukongviriyapan; Phromsopha; Tassaneeyakul; Sripa; Hahnvajanawong; Bhudhisawasdi

Xenobiotica, 2006 , vol. 36, # 1 p. 15 - 28 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

NA

Arylamine Nacetyltransferase 1 [human]:Wild

liver

Cytosol

p-Aminobenzoic acid

1000 µM

Xenobiotica, 2006 , vol...

Title/Abstract Full Text View citing articles Show Details

Kukongviriyapan; Phromsopha; Tassaneeyakul; Sripa; Hahnvajanawong; Bhudhisawasdi

Xenobiotica, 2006 , vol. 36, # 1 p. 15 - 28 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

NA

Arylamine Nacetyltransferase 2 [human]:Wild

liver

Cytosol

Sulphadimidine

1000 µM

Xenobiotica, 2006 , vol...

Title/Abstract Full Text View citing articles Show Details

Kukongviriyapan; Phromsopha; Tassaneeyakul; Sripa; Hahnvajanawong; Bhudhisawasdi

Xenobiotica, 2006 , vol. 36, # 1 p. 15 - 28 Title/Abstract Full Text View citing articles Show Details

1

Foldincrease

NA

Caco-2

[3H]-Ochratoxin A

50 µM

Toxicology Letters, 2005...

Title/Abstract Full Text View citing articles Show Details

Sergent, Therese; Garsou, Serge; Schaut, Annelore; De Saeger, Sarah; Pussemier, Luc; Van Peteghem, Carlos; Larondelle, Yvan; Schneider, Yves-Jacques

Toxicology Letters, 2005 , vol. 159, # 1 p. 60 - 70 Title/Abstract Full Text View citing articles Show Details

4.15

Ki

=

70

µM

Inhibitor

Cytochrome P450 3A4:Wild

Current drug metabolism,...

Title/Abstract Full Text Show Details

Cytochrome P450 1A2 [Rattus norvegicus]:Wild

Current Drug Metabolism,...

Title/Abstract Full Text View citing articles Show Details

Cytochrome P450 3A1 [human]:Wild

Cytochrome P450 3A4 [human]:Wild

liver

Cytochrome P450 3A4:Wild

Murray, Michael

Current drug metabolism, 2006 , vol. 7, # 1 p. 67 - 81 Title/Abstract Full Text Show Details

Activity

=

1

mM

Inhibitor

Ow, Yin-Yin; Stupans, Ieva

Current Drug Metabolism, 2003 , vol. 4, # 3 p. 241 - 248 Title/Abstract Full Text View citing articles Show Details

4.15

Ki

=

70

µM

Radioligand (/ligand)

Current Drug Metabolism,...

Title/Abstract Full Text View citing articles Show Details

Ow, Yin-Yin; Stupans, Ieva

Current Drug Metabolism, 2003 , vol. 4, # 3 p. 241 - 248 Title/Abstract Full Text View citing articles Show Details

3.21

IC50

615.2

μM

Inhibitor

Microsome

testosterone

14 2939 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

3.17

IC50

669.5

μM

Inhibitor

testosterone

14 2939 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

4.3

IC50

50.3

μM

Inhibitor

Cytochrome P450 3A4:Wild

testosterone

14 2939 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details


Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

3.13

IC50

738

μM

Inhibitor

Cytochrome P450 3A4:Wild

testosterone

14 2939 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

4.23

IC50

59.2

μM

Inhibitor

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

testosterone

14 2939 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

testosterone

14 2939 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

3.14

IC50

722.8

μM

Inhibitor

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Inhibitor

Cytochrome P450 3A4:Wild

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Moderate

Inhibitor

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Inhibitor

Cytochrome P450 3A4:Wild

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

pX

Parameter % Inhibition

Value (qual) Moderate

Value (quant)

Unit

Action on Target Inhibitor

Target

Tissue/Organ

Cell

Cell fraction

Cytochrome P450 3A4:Wild

Substrate /Carried Molecule

Dose

Reference (expand all/collapse all)

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

% Inhibition

High

Inhibitor

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

% Inhibition

High

Inhibitor

Cytochrome P450 3A4:Wild


Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

% Inhibition

High

Inhibitor

Cytochrome P450 3A4:Wild

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

% Inhibition

High

Inhibitor

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

% Inhibition

High

Inhibitor

Cytochrome P450 3A4:Wild

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

Inhibitor

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Low

Inhibitor

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

% Inhibition

Moderate

Inhibitor

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

testosterone

588 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

KI

485

μM

Inactivator

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

testosterone

01764 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

01764 μM

Xenobiotica, 2015 , vol...

Title/Abstract Full Text View citing articles Show Details

85 μM

Patent: US2016/184298 ...

Title/Abstract Full Text Show Details

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

kinact

0.05

min1

Inactivator

Cytochrome P450 3A4 [human]:Wild

liver

Microsome

testosterone

Pu, Qiang-Hong; Shi, Liang; Yu, Chao

Xenobiotica, 2015 , vol. 45, # 3 p. 213 - 217 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

8.051

%

Inhibitor

UDPglucuronyltransferase 2B [Sprague Dawley rat]:Wild

liver

Microsome

NATIONAL DEFENSE MEDICAL CENTER; OLIVER, YOA-PU HU; HSIONG, CHENG-HUEI; WANG, MEI-TING; PAO, LI-HENG

Patent: US2016/184298 A1, 2016 ;

nalbuphine


Title/Abstract Full Text Show Details

1

% Inhibition

12.233

%

Inhibitor

UDPglucuronyltransferase 2B [Sprague Dawley rat]:Wild

liver

Microsome

nalbuphine

850 μM

Patent: US2016/184298 ...

Title/Abstract Full Text Show Details

nalbuphine

8.5 μM

Patent: US2016/184298 ...

Title/Abstract Full Text Show Details

30 μg/ml

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

NATIONAL DEFENSE MEDICAL CENTER; OLIVER, YOA-PU HU; HSIONG, CHENG-HUEI; WANG, MEI-TING; PAO, LI-HENG

Patent: US2016/184298 A1, 2016 ; Title/Abstract Full Text Show Details

1

% Inhibition

15.842

%

Inhibitor

UDPglucuronyltransferase 2B [Sprague Dawley rat]:Wild

liver

Microsome

NATIONAL DEFENSE MEDICAL CENTER; OLIVER, YOA-PU HU; HSIONG, CHENG-HUEI; WANG, MEI-TING; PAO, LI-HENG

Patent: US2016/184298 A1, 2016 ; Title/Abstract Full Text Show Details

3.75

Amount increase

Active

peritoneum macrophage

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

4.05

Amount increase

Active

peritoneum macrophage

15 60 μg/ml

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

3.75

Amount increase

Active

peritoneum macrophage

30 μg/ml

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

3.45

Amount increase

Active

peritoneum macrophage

60 μg/ml

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

3.83

% decrease

Active

25.0 μg/ml

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

3.53

% decrease

Active

50.0 μg/ml

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Li, Zhi-Jian; Liu, Meng; Dawuti, Gulina; Dou, Qin; Ma, Yu; Liu, Heng-Ge; Aibai, Silafu

Phytotherapy Research, 2017 , vol. 31, # 7 p. 1039 - 1045 Title/Abstract Full Text View citing articles Show Details

4.31

IC50

49

μM

liver

Microsome (pooled)

protocatechuic acid

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details


Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng

Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

Papp (transport)

1E-08

cm/s

Substrate

Multidrug resistance protein 4:Wild

MDCKMDR1 cell line

2 μM

ACS Chemical Neuroscienc...

Title/Abstract Full Text View citing articles Show Details

Deora, Girdhar Singh; Kantham, Srinivas; Chan, Stephen; Dighe, Satish N.; Veliyath, Suresh K.; McColl, Gawain; Parat, Marie-Odile; McGeary, Ross P.; Ross, Benjamin P.

ACS Chemical Neuroscience, 2017 , vol. 8, # 12 p. 2667 - 2675 Title/Abstract Full Text View citing articles Show Details

Transport ratio

29.3

no unit

Substrate

Multidrug resistance protein 4:Wild

MDCKMDR1 cell line

2 μM

ACS Chemical Neuroscienc...

Title/Abstract Full Text View citing articles Show Details

Deora, Girdhar Singh; Kantham, Srinivas; Chan, Stephen; Dighe, Satish N.; Veliyath, Suresh K.; McColl, Gawain; Parat, Marie-Odile; McGeary, Ross P.; Ross, Benjamin P.

ACS Chemical Neuroscience, 2017 , vol. 8, # 12 p. 2667 - 2675 Title/Abstract Full Text View citing articles Show Details

%

65

%

Substrate

Multidrug resistance protein 4:Wild

MDCKMDR1 cell line

2 μM

ACS Chemical Neuroscienc...

Title/Abstract Full Text View citing articles Show Details

Deora, Girdhar Singh; Kantham, Srinivas; Chan, Stephen; Dighe, Satish N.; Veliyath, Suresh K.; McColl, Gawain; Parat, Marie-Odile; McGeary, Ross P.; Ross, Benjamin P.

ACS Chemical Neuroscience, 2017 , vol. 8, # 12 p. 2667 - 2675 Title/Abstract Full Text View citing articles Show Details

Qualitative Information 1 of 6

2 of 6

3 of 6

Biological material

human HASMC cell line

Assay Description

Effect : cholesterol uptake; inhibition of Figure 11 is a graph showing the effect of active compounds from EO on uptake of cholesterol in human aortic smooth muscle cells. Confluent culture of cells grown in 96 well plates was incubated in serum- free medium with [3H] cholesterol (5 μCi/ml) with and without active fractions. After 24 h the

Results

title compound markedly inhibited cholesterol uptake in cells; figure is given

Citation

THE JOHNS HOPKINS UNIVERSITY; MERLION PHARMACEUTICAL PTC LTD

Patent: WO2008/80162 A2, 2008 ; Title/Abstract Full Text Show Details

Biological material

3T3-L1 cell line

Assay Description

Effect : glucose uptake differentiated cells tested; incubation time with title comp.: 30 min

Results

maximal percentage uptake 90 %

Citation

Vishnu Prasad; Anjana; Banerji, Asoke; Gopalakrishnapillai, Anilkumar

FEBS Letters, 2010 , vol. 584, # 3 p. 531 - 536 Title/Abstract Full Text View citing articles Show Details

Effect

Anti-Atherogenis

Biological material

Mus musculus

Assay Description

Effect : Ox-LDL cellular uptake Bioassay : J774 A.1 macrophage Ox-LDL: oxidized low-density lipoprotein

Results

Ox-LDL cellular uptake reduction 44 %

Citation

Aviram, Michael; Volkova, Nina; Dreher, Mark; Rosenblat, Mira; Coleman, Raymond; Reddy, Muntha Kesava; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2008 , vol. 56, # 3 p. 1148 - 1157 Title/Abstract Full Text View citing articles Show Details


4 of 6

5 of 6

6 of 6

Biological material

human Caco-2

Assay Description

Effect : |transport Bioassay : HBSS: Hank's balanced salt solution monolayer cells cultured; title comp. solution pH 6.0 or 7.4 added to apical side, HBSS pH 7.4 added to basolateral side; well incubated at 37 deg C; distribution of title comp. measured by HPLC

Results

title comp. transport in apical-basolateral direction was independent of pH and linearly increased with increasing concentration of title comp.; transport presumably via paracellular pathway

Citation

Konishi, Yutaka; Kobayashi, Shoko; Shimizu, Makoto

Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 11 p. 2317 - 2324 Title/Abstract Full Text View citing articles Show Details

Assay Description

Partition Coefficient of the compound was determined

Citation

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

Assay Description

Partition Coefficient of the compound was determined

Citation

Locatelli, Claudriana; Rosso, Rober; Santos-Silva, Maria C.; de Souza, Camila A.; Licinio, Marley A.; Leal, Paulo; Bazzo, Maria L.; Yunes, Rosendo A.; Creczynski-Pasa, Tania B.

Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3791 - 3799 Title/Abstract Full Text View citing articles Show Details

Pharmacokinetic (8) Quantitative Results pX

Parameter

Value (qual)

Value (quant)

Unit

Biological Species

Route of administration

Dose

Dosing regimen

Population

Reference (expand all/collapse all)

Cmax

~

1.8

µM

human

Current Drug Metabolism,...

Title/Abstract Full Text View citing articles Show Details

Ow, Yin-Yin; Stupans, Ieva

Current Drug Metabolism, 2003 , vol. 4, # 3 p. 241 - 248 Title/Abstract Full Text View citing articles Show Details

t1/2

1.88

h

Wistar rat

oral administration

15 mg/kg

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng

Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

Tmax

1.17

h

Wistar rat

oral administration

15 mg/kg

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng

Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

Cmax

844.97

ng/ml

Wistar rat

oral administration

15 mg/kg

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng

Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

AUC

2402.35

ng/h/ml

Wistar rat

oral administration

15 mg/kg

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details


Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng

Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

MRT

3.08

h

Wistar rat

oral administration

15 mg/kg

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng

Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

Vc/F

16.97

l/kg

Wistar rat

oral administration

15 mg/kg

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng

Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

Clc/F

5.91

l/h/kg

Wistar rat

oral administration

15 mg/kg

Journal of Pharmaceutica...

Title/Abstract Full Text View citing articles Show Details

Wang, Yuan; Li, Qing; Dai, Yue; Pan, Ronghua; Xia, Yufeng

Journal of Pharmaceutical and Biomedical Analysis, 2018 , vol. 148, p. 128 - 135 Title/Abstract Full Text View citing articles Show Details

Toxicity/Safety Pharmacology (472) Quantitative Results pX

Parameter

Value (qual)

Value (quant)

Unit

Action on Target

Target

Tissue/Organ

Cell

Bioassay

Dose

Effect

Reference (expand all/collapse all)

3.35

CC50

0.45

mM

Cell/tumor cell: proliferation/viability/growth

Antineoplastic

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Ito, Hideyuki; Kobayashi, Eri; Takamatsu, Yoshie; Li, Shu-Hua; Hatano, Tsutomu; Sakagami, Hiroshi; Kusama, Kaoru; Satoh, Kazue; Sugita, Daigo; Shimura, Susumu; Itoh, Yoshio; Yoshida, Takashi

Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 5 p. 687 - 693 Title/Abstract Full Text View citing articles Show Details

3.33

CC50

0.47

mM

Cell/tumor cell: proliferation/viability/growth

Antineoplastic

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Ito, Hideyuki; Kobayashi, Eri; Takamatsu, Yoshie; Li, Shu-Hua; Hatano, Tsutomu; Sakagami, Hiroshi; Kusama, Kaoru; Satoh, Kazue; Sugita, Daigo; Shimura, Susumu; Itoh, Yoshio; Yoshida, Takashi

Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 5 p. 687 - 693 Title/Abstract Full Text View citing articles Show Details

3.28

CC50

0.53

mM

fibroblast

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Chemical and Pharmaceuti...

Title/Abstract Full Text View citing articles Show Details

Ito, Hideyuki; Kobayashi, Eri; Takamatsu, Yoshie; Li, Shu-Hua; Hatano, Tsutomu; Sakagami, Hiroshi; Kusama, Kaoru; Satoh, Kazue; Sugita, Daigo; Shimura, Susumu; Itoh, Yoshio; Yoshida, Takashi

Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 5 p. 687 - 693 Title/Abstract Full Text View citing articles Show Details

3.59

IC50

44

µg/mL

U-87 MG

Cell/tumor cell: proliferation/viability/growth

Antineoplastic

Fitoterapia, 2011 , vol...

Title/Abstract Full Text View citing articles Show Details

Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.

Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details

3.66

IC50

37

µg/mL

Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.

Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284

SK-MEL28 cell line

Cell/tumor cell: proliferation/viability/growth

Antineoplastic

Fitoterapia, 2011 , vol...

Title/Abstract Full Text View citing articles Show Details


Title/Abstract Full Text View citing articles Show Details

4.19

IC50

11

µg/mL

SK-OV-3 cell line

Cell/tumor cell: proliferation/viability/growth

Antineoplastic

Fitoterapia, 2011 , vol...

Title/Abstract Full Text View citing articles Show Details

Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.

Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details

3.85

IC50

24

µg/mL

ARPE-19 cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Fitoterapia, 2011 , vol...

Title/Abstract Full Text View citing articles Show Details

Salem, Manar M.; Davidorf, Frederick H.; Abdel-Rahman, Mohamed H.

Fitoterapia, 2011 , vol. 82, # 8 p. 1279 - 1284 Title/Abstract Full Text View citing articles Show Details

3.94

IC50

19.47

µg/mL

Cell/tumor cell: proliferation/viability/growth

<= 40 µg/mL

Antineoplastic

Molecules, 2010 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Chia, Yi-Chen; Rajbanshi, Ranjan; Calhoun, Colonya; Chiu, Robert H.

Molecules, 2010 , vol. 15, # 11 p. 8377 - 8389 Title/Abstract Full Text View citing articles Show Details

2.36

MBC

0.75

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.95

MIC

0.19

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.36

MBC

0.75

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.43

MBC

0.63

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.43

MBC

0.63

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.53

MBC

0.5

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.23

MBC

1

mg/mL

Cell/tumor cell:

Antibiotic

Molecules, 2011 , vol. ...


proliferation/viability/growth

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MBC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.36

MBC

0.75

mg/mL

Cell/tumor cell: proliferation/viability/growth

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MBC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MBC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.36

MBC

0.75

mg/mL

Cell/tumor cell: proliferation/viability/growth

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

pX

Parameter

Value (qual)

Value (quant)

Unit

1

MBC

>

3

mg/mL

Action on Target

Target

Tissue/Organ

Cell

Effect

Reference (expand all/collapse all)

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Bioassay

Dose

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MBC

>

3

mg/mL

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.36

MBC

0.75

mg/mL

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details


2.43

MBC

0.63

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MBC

>

3

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MBC

>

3

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.36

MBC

0.75

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MBC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MBC

>

3

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

0.25

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MIC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MIC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

0.25

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details


Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MIC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

0.25

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.43

MIC

0.63

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MIC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.65

MIC

0.38

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.43

MIC

0.63

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

3

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

3

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

0.25

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270


Title/Abstract Full Text View citing articles Show Details

2.13

MIC

1.25

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

3

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

3

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.74

MIC

0.31

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

2.95

MIC

0.19

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

3

mg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2011 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Jiamboonsri, Pimsumon; Pithayanukul, Pimolpan; Bavovada, Rapepol; Chomnawang, Mullika T.

Molecules, 2011 , vol. 16, # 8 p. 6255 - 6270 Title/Abstract Full Text View citing articles Show Details

3.44

MIC50

62.5

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko

Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details

3.44

MIC50

62.5

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko

Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details

4.39

MIC90

62.5

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko

Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details

4.39

MIC90

62.5

mg/L

Cell/tumor cell:

Antibiotic

Antimicrobial Agents and...


proliferation/viability/growth

Title/Abstract Full Text View citing articles Show Details

Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko

Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details

3.74

MIC

31.3 62.5

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko

Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details

3.74

MIC

31.3 62.5

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Antimicrobial Agents and...

Title/Abstract Full Text View citing articles Show Details

Shibata, Hirofumi; Kondo, Kyoko; Katsuyama, Ryo; Kawazoe, Kazuyoshi; Sato, Yoichi; Murakami, Kotaro; Takaishi, Yoshihisa; Arakaki, Naokatu; Higuti, Tomihiko

Antimicrobial Agents and Chemotherapy, 2005 , vol. 49, # 2 p. 549 - 555 Title/Abstract Full Text View citing articles Show Details

4.9

MEC

12.5

µM

MCF7

Cell/tumor cell: proliferation/viability/growth

6.30000 µM

Cytotoxic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Fernandes, Iva; Faria, Ana; Azevedo, Joana; Soares, Susana; Calhau, Conceiao; De Freitas, Victor; Mateus, Nuno

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3785 - 3792 Title/Abstract Full Text View citing articles Show Details

2.82

MIC50

256

mg/L

Cell/tumor cell: proliferation/viability/growth

0.500000 mg/L

Antibiotic

Planta Medica, 2008 , v...

Title/Abstract Full Text View citing articles Show Details

Lin, Rong-Dih; Chin, Yi-Ping; Hou, Wen-Chi; Lee, Mei-Hsien

Planta Medica, 2008 , vol. 74, # 8 p. 840 - 846 Title/Abstract Full Text View citing articles Show Details

3.78

MIC90

256

mg/L

Cell/tumor cell: proliferation/viability/growth

0.500000 mg/L

Antibiotic

Planta Medica, 2008 , v...

Title/Abstract Full Text View citing articles Show Details

Lin, Rong-Dih; Chin, Yi-Ping; Hou, Wen-Chi; Lee, Mei-Hsien

Planta Medica, 2008 , vol. 74, # 8 p. 840 - 846 Title/Abstract Full Text View citing articles Show Details

3.12

MIC

128 256

mg/L

Cell/tumor cell: proliferation/viability/growth

0.500000 mg/L

Antibiotic

Planta Medica, 2008 , v...

Title/Abstract Full Text View citing articles Show Details

Lin, Rong-Dih; Chin, Yi-Ping; Hou, Wen-Chi; Lee, Mei-Hsien

Planta Medica, 2008 , vol. 74, # 8 p. 840 - 846 Title/Abstract Full Text View citing articles Show Details

2.63

MIC

400

mg/L

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.93

MIC

200

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.33

MIC

800

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details


2.93

MIC

200

mg/L

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Bioscience, biotechnolog...

Title/Abstract Full Text Show Details

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

3.53

MIC

50

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.63

MIC

400

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.63

MIC

400

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.93

MIC

200

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.93

MIC

200

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.63

MIC

400

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.93

MIC

200

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

3.23

MIC

100

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

3.23

MIC

100

mg/L

Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

2.93

MIC

200

mg/L


Yamamoto, Hiroyo; Ogawa, Tomohiko

Bioscience, biotechnology, and biochemistry, 2002 , vol. 66, # 4 p. 921 - 924 Title/Abstract Full Text Show Details

ZI

7.75

mm

Cell/tumor cell: proliferation/viability/growth

1000 µg/mL

Antimicrobial

Medicinal Chemistry, 201...

Title/Abstract Full Text View citing articles Show Details

Saavedra, Maria J.; Borges, Anabela; Dias, Carla; Aires, Alfredo; Bennett, Richard N.; Rosa, Eduardo S.; Simoes, Manuel

Medicinal Chemistry, 2010 , vol. 6, # 3 p. 174 - 183 Title/Abstract Full Text View citing articles Show Details

ZI

9

mm

Cell/tumor cell: proliferation/viability/growth

1000 µg/mL

Antimicrobial

Medicinal Chemistry, 201...

Title/Abstract Full Text View citing articles Show Details

Saavedra, Maria J.; Borges, Anabela; Dias, Carla; Aires, Alfredo; Bennett, Richard N.; Rosa, Eduardo S.; Simoes, Manuel

Medicinal Chemistry, 2010 , vol. 6, # 3 p. 174 - 183 Title/Abstract Full Text View citing articles Show Details

ZI

8

mm

Cell/tumor cell: proliferation/viability/growth

1000 µg/mL

Antimicrobial

Medicinal Chemistry, 201...

Title/Abstract Full Text View citing articles Show Details

Saavedra, Maria J.; Borges, Anabela; Dias, Carla; Aires, Alfredo; Bennett, Richard N.; Rosa, Eduardo S.; Simoes, Manuel

Medicinal Chemistry, 2010 , vol. 6, # 3 p. 174 - 183 Title/Abstract Full Text View citing articles Show Details

ZI

10

mm

Cell/tumor cell: proliferation/viability/growth

1000 µg/mL

Antimicrobial

Medicinal Chemistry, 201...

Title/Abstract Full Text View citing articles Show Details

Saavedra, Maria J.; Borges, Anabela; Dias, Carla; Aires, Alfredo; Bennett, Richard N.; Rosa, Eduardo S.; Simoes, Manuel

Medicinal Chemistry, 2010 , vol. 6, # 3 p. 174 - 183 Title/Abstract Full Text View citing articles Show Details

5.11

IC50

7.75

µM

HL-60 cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Tian, Li-Wen; Xu, Min; Li, Yan; Li, Xing-Yao; Wang, Dong; Zhu, Hong-Tao; Yang, Chong-Ren; Zhang, Ying-Jun

Chemistry and Biodiversity, 2012 , vol. 9, # 1 p. 123 - 130 Title/Abstract Full Text View citing articles Show Details

5.23

EC50

1

mg/L

Cell/tumor cell: proliferation/viability/growth

0.600000 mg/L

Toxic

Water Research, 2000 , ...

Title/Abstract Full Text View citing articles Show Details

Nakai, Satoshi; Inoue, Yutaka; Hosomi, Masaaki; Murakami, Akihiko

Water Research, 2000 , vol. 34, # 11 p. 3026 - 3032 Title/Abstract Full Text View citing articles Show Details

1.73

MIC

3200

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi; Nihei, Atsuko

Journal of Agricultural and Food Chemistry, 2004 , vol. 52, # 5 p. 1072 - 1076 Title/Abstract Full Text View citing articles Show Details

EC50

43.5

µmol

SK-BR-3 cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

EC50

71.3

µmol

AZ-521 cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details


EC50

>

100

µmol

A-549

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

EC50

19.3

µmol

HL-60 cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

4.16

IC50

68.7

µM

Caco-2

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Forester, Sarah C.; Waterhouse, Andrew L.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5320 - 5327 Title/Abstract Full Text View citing articles Show Details

2.63

MBC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

0.59

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MBC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

0.59

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MBC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

1.18

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MBC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details


Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

0.59

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MBC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

0.59

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MBC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

1.18

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MBC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

0.59

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MBC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MIC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422


Title/Abstract Full Text View citing articles Show Details

2.63

MFC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

1.18

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.93

MFC

1.18

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

0.59

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.53

MFC

2.95

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

1.18

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MFC

0.295

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

0.295

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MFC

0.295

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.63

MIC

0.236

µmol/mL

Cell/tumor cell:

Antifungal

Journal of Agricultural ...


proliferation/viability/growth

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.75

MFC

0.177

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.93

MIC

0.118

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.23

MFC

0.59

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

0.295

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.63

MFC

2.36

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

1.18

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.93

MFC

1.18

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

0.59

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.53

MFC

2.95

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details


Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

1.18

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MFC

0.295

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MFC

0.295

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.63

MFC

0.236

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

0.295

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.53

MIC

0.295

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

3.75

MIC

0.177

µmol/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Karioti, Anastasia; Sokovic, Marina; Ciric, Ana; Koukoulitsa, Catherine; Bilia, Anna Rita; Skaltsa, Helen

Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 12 p. 6412 - 6422 Title/Abstract Full Text View citing articles Show Details

4.34

% Inhibition

39.9

%

Cell/tumor cell: proliferation/viability/growth

30 µM

Antineoplastic

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Zhang, Weihe; Liu, Yi; Chen, Xiaozhuo; Bergmeier, Stephen C.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2191 - 2194 Title/Abstract Full Text View citing articles Show Details

1.73

MIC

3200

mg/L

Kubo, Isao; Xiao, Ping; Nihei, Ken-Ichi; Fujita, Ken-Ichi; Yamagiwa, Yoshiro; Kamikawa, Tadao

Journal of agricultural and food chemistry, 2002 , vol. 50, # 14 p. 3992 - 3998 Title/Abstract Full Text Show Details

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of agricultural ...

Title/Abstract Full Text Show Details


3.8

IC50

160

µM

BT-549 cell line

Cell/tumor cell: proliferation/viability/growth

Antineoplastic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Antineoplastic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Antineoplastic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Antineoplastic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Antineoplastic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Proliferative

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details

3.63

IC50

235

µM

HT-29

Cell/tumor cell: proliferation/viability/growth

Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details

4.15

IC50

70.5

µM

SK-MEL cell line

Cell/tumor cell: proliferation/viability/growth

Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details

3.48

IC50

332

µM

KB

Cell/tumor cell: proliferation/viability/growth

Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details

3.98

IC50

105

µM

SK-OV-3 cell line

Cell/tumor cell: proliferation/viability/growth

Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details

3.47

IC50

341

µM

Cell/tumor cell: proliferation/viability/growth

Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

500

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.53

MIC

500

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.23

MIC

1000

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.23

MIC

1000

mg/L

Cell/tumor cell: proliferation/viability/growth


Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.23

MIC

1000

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.23

MIC

1000

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

250

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

250

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

250

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.23

MIC

1000

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

2.83

MIC

250

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

3.74

MIC

31.3 62.5

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

4.33

MIC

7.9 31.3

mg/L

Cell/tumor cell: proliferation/viability/growth

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details


2.53

MIC

500

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

3.12

MIC

128

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Planta Medica, 2003 , v...

Title/Abstract Full Text View citing articles Show Details

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

3.12

MIC

128

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Planta Medica, 2003 , v...

Title/Abstract Full Text View citing articles Show Details

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

3.12

MIC

128

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Planta Medica, 2003 , v...

Title/Abstract Full Text View citing articles Show Details

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

3.12

MIC

128

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Planta Medica, 2003 , v...

Title/Abstract Full Text View citing articles Show Details

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

3.12

MIC

128

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Planta Medica, 2003 , v...

Title/Abstract Full Text View citing articles Show Details

Hatano, Tsutomu; Kusuda, Miwako; Hori, Mami; Shiota, Sumiko; Tsuchiya, Tomofusa; Yoshida, Takashi

Planta Medica, 2003 , vol. 69, # 11 p. 984 - 989 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Fitoterapia, 2009 , vol...

Title/Abstract Full Text View citing articles Show Details

Liu, Manjuan; Katerere, David R.; Gray, Alexander I.; Seidel, Veronique

Fitoterapia, 2009 , vol. 80, # 6 p. 369 - 373 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Fitoterapia, 2009 , vol...

Title/Abstract Full Text View citing articles Show Details

Liu, Manjuan; Katerere, David R.; Gray, Alexander I.; Seidel, Veronique

Fitoterapia, 2009 , vol. 80, # 6 p. 369 - 373 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Fitoterapia, 2009 , vol...

Title/Abstract Full Text View citing articles Show Details

Liu, Manjuan; Katerere, David R.; Gray, Alexander I.; Seidel, Veronique

Fitoterapia, 2009 , vol. 80, # 6 p. 369 - 373 Title/Abstract Full Text View citing articles Show Details

1

CC

>

500

µM

Hep G2

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details


Wolfe, Kelly L.; Rui, Hai Liu

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 22 p. 8896 - 8907 Title/Abstract Full Text View citing articles Show Details

GP (%)

107

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

46

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

96

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

109

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

83

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

112

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

99

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

114

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

70

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349


Title/Abstract Full Text View citing articles Show Details

GP (%)

126

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

110

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

107

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

105

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

97

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

GP (%)

102

%

Cell/tumor cell: proliferation/viability/growth

Antimicrobial

Journal of Agricultural ...

Title/Abstract Full Text View citing articles Show Details

Bialonska, Dobroslawa; Kasimsetty, Sashi G.; Schrader, Kevin K.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 18 p. 8344 - 8349 Title/Abstract Full Text View citing articles Show Details

1.73

MIC

3200

mg/L

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Xiao, Ping; Fujita, Ken'ichi

Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 2 p. 113 - 116 Title/Abstract Full Text View citing articles Show Details

4.36

LC50

43.9 57.4

µM

K-562 cell line

Cell/tumor cell: proliferation/viability/growth

Antineoplastic

Molecules, 2008 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Mitsuhashi, Shinya; Saito, Akiko; Nakajima, Noriyuki; Shima, Hiroshi; Ubukata, Makoto

Molecules, 2008 , vol. 13, # 12 p. 2998 - 3006 Title/Abstract Full Text View citing articles Show Details

4.54

LC50

28.7 29.2

µM

HEK293T cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Molecules, 2008 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Mitsuhashi, Shinya; Saito, Akiko; Nakajima, Noriyuki; Shima, Hiroshi; Ubukata, Makoto

Molecules, 2008 , vol. 13, # 12 p. 2998 - 3006 Title/Abstract Full Text View citing articles Show Details

2.03

MIC

1600

mg/L

Cell/tumor cell:

3200

Antibiotic

Journal of Agricultural ...


proliferation/viability/growth

mg/L

Title/Abstract Full Text View citing articles Show Details

Kubo, Isao; Fujita, Ken-Ichi; Nihei, Ken-Ichi

Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 23 p. 6692 - 6696 Title/Abstract Full Text View citing articles Show Details

3.23

IC50

587.8

µM

Cell/tumor cell: proliferation/viability/growth

50 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details

4.44

IC50

6.2

mg/L

Cell/tumor cell: proliferation/viability/growth

50 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details

4.53

IC50

29.4

µM

Cell/tumor cell: proliferation/viability/growth

50 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details

3.28

IC50

524.3

µM

keratinocyte

Cell/tumor cell: proliferation/viability/growth

50 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details

4.14

IC50

72.3

µM

HtTA-1 cell line

Cell/tumor cell: proliferation/viability/growth

50 mg/L

Cytotoxic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Sakaguchi, Nahoko; Inoue, Makoto; Isuzugawa, Kazuto; Ogihara, Yukio; Hosaka, Kunio

Biological and Pharmaceutical Bulletin, 1999 , vol. 22, # 5 p. 471 - 475 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

200

mg/L

Cell/tumor cell: proliferation/viability/growth

0.100000 mg/L

Antibiotic

Biological and Pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Bae, Eun-Ah; Han, Myung Joo; Kim, Nam-Jae; Kim, Dong-Hyun

Biological and Pharmaceutical Bulletin, 1998 , vol. 21, # 9 p. 990 - 992 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

8

%

Hep G2

Cell/tumor cell: proliferation/viability/growth

1 µg/mL

Cytotoxic

Asian Journal of Chemist...

Title/Abstract Full Text View citing articles Show Details

Xiang, Zhao Bao; Mo, Hai Qing; Qu, Zhong Tang; Xu, Hong Mei; Jiang, Hum Zhong

Asian Journal of Chemistry, 2011 , vol. 23, # 8 p. 3759 - 3760 Title/Abstract Full Text View citing articles Show Details

1

LD50

>

1000

µM

Biological and pharmaceu...

Title/Abstract Full Text View citing articles Show Details

Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo

Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details

4.52

LD50

=

30

µM

Biological and pharmaceu...

Title/Abstract Full Text View citing articles Show Details


Koide, Tatsuo; Nose, Mitsuhiko; Ogihara, Yuiko; Yabu, Yoshisada; Ohta, Nobuo

Biological and pharmaceutical bulletin, 2002 , vol. 25, # 1 p. 131 - 133 Title/Abstract Full Text View citing articles Show Details

4.58

LC50

=

4.53

µg/mL

Cytotoxic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

El-Sayed Ali, Tarik

European Journal of Medicinal Chemistry, 2009 , vol. 44, # 11 p. 4385 - 4392 Title/Abstract Full Text View citing articles Show Details

=

5000

mg/kg

Material Safety Data She...

Full Text Show Details

320

mg/kg

Material Safety Data She...

Full Text Show Details

5000

mg/kg

Material Safety Data She...

Full Text Show Details

THP-1 cell line

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Material Safety Data Sheet Full Text Show Details

LD50

=

Material Safety Data Sheet Full Text Show Details

LD50

=

Material Safety Data Sheet Full Text Show Details

Toxicity

ND

Bandgar, Babasaheb P.; Patil, Sachin A.; Totre, Jalinder V.; Korbad, Balaji L.; Gacche, Rajesh N.; Hote, Baliram S.; Jalde, Shivkumar S.; Chavan, Hemant V.

Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2292 - 2296 Title/Abstract Full Text View citing articles Show Details

1

Toxicity

NA

Toxic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Locatelli, Claudriana; Filippin-Monteiro, Fabiola Branco; Creczynski-Pasa, Tania Beatriz

European Journal of Medicinal Chemistry, 2013 , vol. 60, p. 233 - 239 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details


Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details


MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

2.93

MIC

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

3.23

MIC

100

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details


Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

MLC

>

200

µg/mL

Cell/tumor cell: proliferation/viability/growth

Antifungal

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Gehrke, Ilaine T.S.; Neto, Alexandre T.; Pedroso, Marcelo; Mostardeiro, Clarice P.; Da Cruz, Ivana B.M.; Silva, Ubiratan F.; Ilha, Vinicius; Dalcol, Ionara I.; Morel, Ademir F.

Journal of Ethnopharmacology, 2013 , vol. 148, # 2 p. 486 - 491 Title/Abstract Full Text View citing articles Show Details

4.23

IC50

10

µg/mL

HeLa cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Antiplasmodic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Marčetic̈, Mirjana; Božic̈, Dragana; Milenkovic̈, Marina; Maleševic̈, Nevenka; Radulovic̈, Siniša; Kovačevic̈, Nada

Phytotherapy Research, 2013 , vol. 27, # 11 p. 1658 - 1663 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

10

µg/mL

erythrocyte

Cell/tumor cell: proliferation/viability/growth

Garcia-Alvarez; Moussa; Njomnang Soh; Nongonierma; Abdoulaye; Nicolau-Travers; Fabre; Wdzieczak-Bakala; Ahond; Poupat; Ikhiri; Benoit-Vical

Journal of Ethnopharmacology, 2013 , vol. 149, # 3 p. 676 - 684 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

50

µM

Cell/tumor cell: proliferation/viability/growth

Antifungal

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Cell/tumor cell: proliferation/viability/growth

Antifungal

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Cell/tumor cell: proliferation/viability/growth

Antifungal

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Ito, Shinsaku; Nakagawa, Yasutaka; Yazawa, Satoru; Sasaki, Yasuyuki; Yajima, Shunsuke

Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1812 - 1814 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

50

µM

Ito, Shinsaku; Nakagawa, Yasutaka; Yazawa, Satoru; Sasaki, Yasuyuki; Yajima, Shunsuke

Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1812 - 1814 Title/Abstract Full Text View citing articles Show Details

1

MIC

>

50

µM

Ito, Shinsaku; Nakagawa, Yasutaka; Yazawa, Satoru; Sasaki, Yasuyuki; Yajima, Shunsuke

Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1812 - 1814 Title/Abstract Full Text View citing articles Show Details

pX

Parameter

Value (qual)

Value (quant)

Unit

1

MIC

>

50

µM

Action on Target

Target

Tissue/Organ

Cell

Effect

Reference (expand all/collapse all)

Cell/tumor cell: proliferation/viability/growth

Antifungal

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Molecules, 2013 , vol. ...

Title/Abstract Full Text View citing articles Show Details

Cell/tumor cell:

Cytotoxic

Journal of Medicinal Che...

Bioassay

Dose

Ito, Shinsaku; Nakagawa, Yasutaka; Yazawa, Satoru; Sasaki, Yasuyuki; Yajima, Shunsuke

Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1812 - 1814 Title/Abstract Full Text View citing articles Show Details

3.41

MIC

66.67

µg/mL

Deng, Ke-Zhong; Xiong, Ying; Zhou, Bin; Guan, Yong-Mei; Luo, Yong-Ming

Molecules, 2013 , vol. 18, # 10 p. 11859 - 11865 Title/Abstract Full Text View citing articles Show Details

3.79

IC50

163.1

µM

TA3/Ha cell


line

proliferation/viability/growth

Title/Abstract Full Text View citing articles Show Details

Jara, José A.; Castro-Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello, Antonio; Kemmerling, Ulrike; Maya, Juan Diego; Ferreira, Jorge

Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2440 - 2454 Title/Abstract Full Text View citing articles Show Details

3.8

IC50

160.2

µM

TA3-MTX-R cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Jara, José A.; Castro-Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello, Antonio; Kemmerling, Ulrike; Maya, Juan Diego; Ferreira, Jorge

Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2440 - 2454 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

200

µM

CCRF-CEM cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Jara, José A.; Castro-Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello, Antonio; Kemmerling, Ulrike; Maya, Juan Diego; Ferreira, Jorge

Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2440 - 2454 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

200

µM

MM3MG cell line

Cell/tumor cell: proliferation/viability/growth

Cytotoxic

Journal of Medicinal Che...

Title/Abstract Full Text View citing articles Show Details

Jara, José A.; Castro-Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello, Antonio; Kemmerling, Ulrike; Maya, Juan Diego; Ferreira, Jorge

Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2440 - 2454 Title/Abstract Full Text View citing articles Show Details

%

93.4

%

B16 melanoma 4A5 cell line

Cell/tumor cell: proliferation/viability/growth

30 µM

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

%

95.8

%

B16 melanoma 4A5 cell line

Cell/tumor cell: proliferation/viability/growth

10 µM

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

%

61.6

%

B16 melanoma 4A5 cell line

Cell/tumor cell: proliferation/viability/growth

100 µM

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

4.86

IC50

13.9

µM

HL-60 cell line

Cell/tumor cell: proliferation/viability/growth

1.00000E06 M

Cytotoxic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

4.54

IC50

29.1

µM

AZ-521 cell line

Cell/tumor cell: proliferation/viability/growth

1.00000E06 M

Cytotoxic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

1

IC50

>

100

µM

A-549

Cell/tumor cell:

1.00000E-

Cytotoxic

Chemistry and Biodiversi...


proliferation/viability/growth

06 M

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

4.26

IC50

54.7

µM

SK-BR-3 cell line

Cell/tumor cell: proliferation/viability/growth

1.00000E06 M

Cytotoxic

Chemistry and Biodiversi...

Title/Abstract Full Text View citing articles Show Details

Zhang, Jie; Nishimoto, Yuki; Tokuda, Harukuni; Suzuki, Nobutaka; Yasukawa, Ken; Kitdamrongtham, Worapong; Akazawa, Hiroyuki; Manosroi, Aranya; Manosroi, Jiradej; Akihisa, Toshihiro

Chemistry and Biodiversity, 2013 , vol. 10, # 10 p. 1866 - 1875 Title/Abstract Full Text View citing articles Show Details

ZI

32.41

mm

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Asian Journal of Chemist...

Title/Abstract Full Text View citing articles Show Details

Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong

Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details

ZI

25.71

mm

Cell/tumor cell: proliferation/viability/growth

Antibiotic

Asian Journal of Chemist...

Title/Abstract Full Text View citing articles Show Details

Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong

Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details

ZI

30.03

mm

Cell/tumor cell: proliferation/viability/growth

Antifungal

Asian Journal of Chemist...

Title/Abstract Full Text View citing articles Show Details

Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong

Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details

ZI

23.85

mm

Cell/tumor cell: proliferation/viability/growth

Antifungal

Asian Journal of Chemist...

Title/Abstract Full Text View citing articles Show Details

Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong

Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details

ZI

23.3

mm

Cell/tumor cell: proliferation/viability/growth

Antifungal

Asian Journal of Chemist...

Title/Abstract Full Text View citing articles Show Details

Wang, Zhiyuan; Gu, Haibin; Chen, Wuyong

Asian Journal of Chemistry, 2014 , vol. 26, # 2 p. 513 - 520 Title/Abstract Full Text View citing articles Show Details

1

% Stimulation

15

%

HUVEC cell line

Cell/tumor cell: proliferation/viability/growth

50 µg/mL

Proliferative

RSC Advances, 2014 , vo...

Title/Abstract Full Text View citing articles Show Details

He, Yonghui; Wang, Juan; Yan, Wei; Huang, Nan

RSC Advances, 2014 , vol. 4, # 1 p. 212 - 221 Title/Abstract Full Text View citing articles Show Details

4.2

% Stimulation

32

%

HUVEC cell line

Cell/tumor cell: proliferation/viability/growth

5 µg/mL

Proliferative

RSC Advances, 2014 , vo...

Title/Abstract Full Text View citing articles Show Details

He, Yonghui; Wang, Juan; Yan, Wei; Huang, Nan

RSC Advances, 2014 , vol. 4, # 1 p. 212 - 221 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

3

%

HUASMC cell line

Cell/tumor cell: proliferation/viability/growth

5 µg/mL

Antiproliferative

RSC Advances, 2014 , vo...

Title/Abstract Full Text View citing articles Show Details


He, Yonghui; Wang, Juan; Yan, Wei; Huang, Nan

RSC Advances, 2014 , vol. 4, # 1 p. 212 - 221 Title/Abstract Full Text View citing articles Show Details

3.67

% Inhibition

58

%

HUASMC cell line

Cell/tumor cell: proliferation/viability/growth

50 µg/mL

Antiproliferative

RSC Advances, 2014 , vo...

Title/Abstract Full Text View citing articles Show Details

He, Yonghui; Wang, Juan; Yan, Wei; Huang, Nan

RSC Advances, 2014 , vol. 4, # 1 p. 212 - 221 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

10.8

%

liver cell

Cell/tumor cell: proliferation/viability/growth

3 µM

Cytotoxic

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

14.2

%

liver cell

Cell/tumor cell: proliferation/viability/growth

10 µM

Cytotoxic

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

4.07

% Inhibition

26

%

liver cell

Cell/tumor cell: proliferation/viability/growth

30 µM

Cytotoxic

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

3.75

% Inhibition

35.9

%

liver cell

Cell/tumor cell: proliferation/viability/growth

100 µM

Cytotoxic

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

8.5

%

L929

Cell/tumor cell: proliferation/viability/growth

100 µM

Cytotoxic

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

2.8

%

L929

Cell/tumor cell: proliferation/viability/growth

30 µM

Cytotoxic

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

2.1

%

L929

Cell/tumor cell: proliferation/viability/growth

3 µM

Cytotoxic

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

0.2

%

L929

Cell/tumor cell: proliferation/viability/growth

10 µM

Cytotoxic

Phytochemistry, 2014 , ...

Title/Abstract Full Text View citing articles Show Details

Morikawa, Toshio; Ninomiya, Kiyofumi; Imura, Katsuya; Yamaguchi, Takahiro; Akagi, Yoshinori; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu

Phytochemistry, 2014 , vol. 102, p. 169 - 181 Title/Abstract Full Text View citing articles Show Details


5.03

% Inhibition

#

100

%

rHSC cell line

Cell/tumor cell: proliferation/viability/growth

30 µg/mL

Cytotoxic

Life Sciences, 2014 , v...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Shu-Chung; Wu, Chi-Hao; Wu, Chun-Chi; Yen, Jung-Hsing; Liu, Mei-Chun; Hsueh, Chi-Mei; Hsu, Shih-Lan

Life Sciences, 2014 , vol. 102, # 1 p. 55 - 64 Title/Abstract Full Text View citing articles Show Details

3.75

% Inhibition

>

50

%

rHSC cell line

Cell/tumor cell: proliferation/viability/growth

30 µg/mL

Cytotoxic

Life Sciences, 2014 , v...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Shu-Chung; Wu, Chi-Hao; Wu, Chun-Chi; Yen, Jung-Hsing; Liu, Mei-Chun; Hsueh, Chi-Mei; Hsu, Shih-Lan

Life Sciences, 2014 , vol. 102, # 1 p. 55 - 64 Title/Abstract Full Text View citing articles Show Details

4.8

IC50

15.7

μM

MCF7

5 - 20 μM

Cytotoxic

Bulletin of the Korean C...

Title/Abstract Full Text View citing articles Show Details

Kim, Tae-Woo; Paveen, Shehlar; Lee, Young Hun; Lee, Yong Sup

Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 4 p. 987 - 988 Title/Abstract Full Text View citing articles Show Details

4.79

IC50

16.1

μM

MCF7

5 - 20 μM

Cytotoxic

Bulletin of the Korean C...

Title/Abstract Full Text View citing articles Show Details

Kim, Tae-Woo; Paveen, Shehlar; Lee, Young Hun; Lee, Yong Sup

Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 4 p. 987 - 988 Title/Abstract Full Text View citing articles Show Details

4.8

IC50

15.8

μM

MDA-MB231

5 - 20 μM

Cytotoxic

Bulletin of the Korean C...

Title/Abstract Full Text View citing articles Show Details

Kim, Tae-Woo; Paveen, Shehlar; Lee, Young Hun; Lee, Yong Sup

Bulletin of the Korean Chemical Society, 2014 , vol. 35, # 4 p. 987 - 988 Title/Abstract Full Text View citing articles Show Details

3.24

IC50

0.58

mM

HEK293 cell line

100 nM 1 mM

Cytotoxic

Patent: US2014/249095 ...

Title/Abstract Full Text Show Details

SH-SY5Y cell line

100 nM 1 mM

Cytotoxic

Patent: US2014/249095 ...

Title/Abstract Full Text Show Details

CCRF-CEM cell line

Cytotoxic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

National Normal University; LEE-CHEN, Guey-Jen; CHEN, Chiung-Mei

Patent: US2014/249095 A1, 2014 ; Title/Abstract Full Text Show Details

3.24

IC50

0.57

mM

National Normal University; LEE-CHEN, Guey-Jen; CHEN, Chiung-Mei

Patent: US2014/249095 A1, 2014 ; Title/Abstract Full Text Show Details

1

CC50

>

250

μM

Rivero-Buceta, Eva; Carrero, Paula; Doyagüez, Elisa G.; Madrona, Andrs; Quesada, Ernesto; Camarasa, Mara Jos; Perz-Prez, Mara Jess; Leyssen, Pieter; Paeshuyse, Jan; Balzarini, Jan; Neyts, Johan; San-Flix, Ana

European Journal of Medicinal Chemistry, 2015 , vol. 92, p. 656 - 671 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

HepG 2

Cytotoxic

PLoS ONE, 2014 , vol. 9...

Title/Abstract Full Text View citing articles Show Details

Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan

PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

L6

Cytotoxic

PLoS ONE, 2014 , vol. 9...

Title/Abstract Full Text View citing articles Show Details

Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan


PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

3T3-L1 cell line

Cytotoxic

PLoS ONE, 2014 , vol. 9...

Title/Abstract Full Text View citing articles Show Details

Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan

PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

RIN-m2F cell line

Cytotoxic

PLoS ONE, 2014 , vol. 9...

Title/Abstract Full Text View citing articles Show Details

Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan

PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

MIN6

Cytotoxic

PLoS ONE, 2014 , vol. 9...

Title/Abstract Full Text View citing articles Show Details

Antu, Kalathookunnel Antony; Riya, Mariam Philip; Mishra, Arvind; Anilkumar, Karunakaran S.; Chandrakanth, Chandrasekharan K.; Tamrakar, Akhilesh K.; Srivastava, Arvind K.; Raghu, K. Gopalan

PLoS ONE, 2014 , vol. 9, # 9 art. no. E105829 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

HT-29 cell line

1 - 100 μM

Antineoplastic

Journal of Pharmacology ...

Title/Abstract Full Text View citing articles Show Details

De Molina, Ana Ramírez; Vargas, Teodoro; Molina, Susana; Sánchez, Jenifer; Martínez-Romero, Jorge; González-Vallinas, Margarita; Martín-Hernández, Roberto; Sánchez-Martínez, Ruth; De Cedrón, Marta Gómez; Dávalos, Alberto; Calani, Luca; Del Rio, Daniele; González-Sarrías, Antonio; Espín, Juan Carlos; Tomás-Barberán, Francisco A.; Reglero, Guillermo

Journal of Pharmacology and Experimental Therapeutics, 2015 , vol. 353, # 2 p. 433 - 444 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

HUVEC cell line

50 μg/ml

Cytotoxic

Environmental Toxicology...

Title/Abstract Full Text View citing articles Show Details

Kang, Nalae; Lee, Ji-Hyeok; Lee, WonWoo; Ko, Ju-Young; Kim, Eun-A; Kim, Jin-Soo; Heu, Min-Soo; Kim, Gwang Hoon; Jeon, You-Jin

Environmental Toxicology and Pharmacology, 2015 , vol. 39, # 2 p. 764 - 772 Title/Abstract Full Text View citing articles Show Details

5.18

% Inhibition

>

90

%

THP-1 cell line

10 μg/ml

Cytotoxic

European Journal of Nutr...

Title/Abstract Full Text View citing articles Show Details

Del Bo, Cristian; Cao, Yi; Roursgaard, Martin; Riso, Patrizia; Porrini, Marisa; Loft, Steffen; Moller, Peter

European Journal of Nutrition, 2016 , vol. 55, # 1 p. 171 - 182 Title/Abstract Full Text View citing articles Show Details

5

% activity

50.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

21.6

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

4.6

% activity

28.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details


4.78

% activity

37.6

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.47

% activity

74.5

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

16.6

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

4.54

% activity

25.6

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

46.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

14.8

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

11.4

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

15.4

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

13

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details


Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

16.2

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

13.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

4.66

% activity

31.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

4.61

% activity

29.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

15.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

9.8

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

15.9

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

12.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

24.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280


Title/Abstract Full Text View citing articles Show Details

1

% activity

20.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.55

% activity

78.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.61

% activity

80.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.77

% activity

85.4

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.98

% activity

90.5

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.61

% activity

80.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.9

% activity

88.8

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.58

% activity

79.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.83

% activity

87.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.27

% activity

65.2

%

10 μM

Phytotherapy Research, 2...


Title/Abstract Full Text View citing articles Show Details Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.39

% activity

70.9

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.45

% activity

74

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.63

% activity

81.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.42

% activity

72.5

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.52

% activity

76.9

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.35

% activity

69.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.48

% activity

75.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

4.89

% activity

43.6

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

4.99

% activity

49.7

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details


Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.42

% activity

72.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.53

% activity

77.2

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.4

% activity

71.3

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.52

% activity

76.8

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.12

% activity

56.8

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

5.25

% activity

64.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details


Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

0

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

14

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

10.9

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

11.2

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

8.5

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

12.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details


Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

10.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

14.7

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

11.6

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

25.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

21.2

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

12.6

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

13

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

12.8

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

11.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280


Title/Abstract Full Text View citing articles Show Details

Mortality rate

18.9

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

Mortality rate

15.8

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

22

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

19.7

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

14.6

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

9.5

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

19.7

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

11.2

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

20.1

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

12.6

%

10 μM

Phytotherapy Research, 2...


Title/Abstract Full Text View citing articles Show Details Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

20.8

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

1

% activity

18.2

%

10 μM

Phytotherapy Research, 2...

Title/Abstract Full Text View citing articles Show Details

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details

4.23

% Inhibition

Active

WI-38 cell line

10 - 200 μg/ml

Cytotoxic

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Chaudhuri, Dipankar; Ghate, Nikhil Baban; Panja, Sourav; Das, Abhishek; Mandal, Nripendranath

PLoS ONE, 2015 , vol. 10, # 12 art. no. E0144280 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

rbl-2h3

10 - 100 μM

Cytotoxic

Journal of Natural Medic...

Title/Abstract Full Text View citing articles Show Details

Shi, Yan-Hong; Zhu, Shu; Tamura, Takayuki; Kadowaki, Makoto; Wang, Zhengtao; Yoshimatsu, Kayo; Komatsu, Katsuko

Journal of Natural Medicines, 2016 , vol. 70, # 2 p. 234 - 240 Title/Abstract Full Text View citing articles Show Details

4.23

% Inhibition

Active

HepG 2

10 μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.93

% Inhibition

Active

HepG 2

20μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.75

% Inhibition

Active

HepG 2

30μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.63

% Inhibition

Active

HepG 2

40μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.53

% Inhibition

Active

HepG 2

50 μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details


Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

4.23

% Inhibition

Active

MCF7

10 μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.93

% Inhibition

Active

MCF7

20μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.75

% Inhibition

Active

MCF7

30μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.63

% Inhibition

Active

MCF7

40μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.53

% Inhibition

Active

MCF7

50 μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

4.23

% Inhibition

Active

Caco-2 cell line

10 μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.93

% Inhibition

Active

Caco-2 cell line

20μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.63

% Inhibition

Active

Caco-2 cell line

40μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.53

% Inhibition

Active

Caco-2 cell line

50 μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details


3.75

% Inhibition

Active

Caco-2 cell line

30μg/ml

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Chen, Mingshun; Zhao, Zhengang; Yu, Shujuan

International Journal of Molecular Sciences, 2016 , vol. 17, # 7 art. no. 993 Title/Abstract Full Text View citing articles Show Details

3.4

IC50

0.4

mM

A-549 cell line

0.01 - 30 mM

Cytotoxic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia

European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details

3.4

IC50

0.4

mM

A-549 cell line

0.01 - 30 mM

Cytotoxic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia

European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details

3.4

IC50

0.4

mM

A-549 cell line

0.01 - 30 mM

Cytotoxic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia

European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details

IC10

<

0.1

mM

BAEC cell line

0.01 - 20 mM

Cytotoxic

European Journal of Medi...

Title/Abstract Full Text View citing articles Show Details

Cassien, Mathieu; Petrocchi, Consuelo; Thétiot-Laurent, Sophie; Robin, Maxime; Ricquebourg, Emilie; Kandouli, Chouaib; Asteian, Alice; Rockenbauer, Antal; Mercier, Anne; Culcasi, Marcel; Pietri, Sylvia

European Journal of Medicinal Chemistry, 2016 , vol. 119, p. 197 - 217 Title/Abstract Full Text View citing articles Show Details

5.25

IC50

0.96

μg/ml

T lymphocyte

3.125 50 μg/ml

Cytotoxic

Drug Design, Development...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng

Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details

% Viability

>

90

%

peripheral blood mononuclear cell

RAW 264.7 cell line

3.125 100 μg/ml

Cytotoxic

Drug Design, Development...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng

Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details

% Viability

>

90

%

3.125 100 μg/ml

Cytotoxic

Drug Design, Development...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Ilangkovan, Menaga; Husain, Khairana; Chan, Kok Meng

Drug Design, Development and Therapy, 2016 , vol. 10, p. 1935 - 1945 Title/Abstract Full Text View citing articles Show Details

3.67

IC50

36

μg/ml

MCF7

3.13 100 μg/ml

Cytotoxic

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details

Tor, Yin Sim; Yazan, Latifah Saiful; Foo, Jhi Biau; Wibowo, Agustono; Ismail, Norsharina; Cheah, Yoke Kqueen; Abdullah, Rasedee; Ismail, Maznah; Ismail, Intan Safinar; Yeap, Swee Keong

PLoS ONE, 2015 , vol. 10, # 6 art. no. E0127441 Title/Abstract Full Text View citing articles Show Details

3.69

IC50

35

μg/ml

MDA-MB231

3.13 100 μg/ml

Cytotoxic

PLoS ONE, 2015 , vol. 1...

Title/Abstract Full Text View citing articles Show Details


Tor, Yin Sim; Yazan, Latifah Saiful; Foo, Jhi Biau; Wibowo, Agustono; Ismail, Norsharina; Cheah, Yoke Kqueen; Abdullah, Rasedee; Ismail, Maznah; Ismail, Intan Safinar; Yeap, Swee Keong

PLoS ONE, 2015 , vol. 10, # 6 art. no. E0127441 Title/Abstract Full Text View citing articles Show Details

4.3

% viability

Active

RAW 264.7 cell line

50 μmol/l

Cytotoxic

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Li, Yi-jie; Xu, Cheng-ting; Lin, Dan-dan; Qin, Jiang-ke; Ye, Gao-jie; Deng, Qing-hua

Bioorganic and Medicinal Chemistry Letters, 2016 , vol. 26, # 15 p. 3425 - 3428 Title/Abstract Full Text View citing articles Show Details

4.3

% viability

Active

RAW 264.7 cell line

50 μmol/l

Cytotoxic

Bioorganic and Medicinal...

Title/Abstract Full Text View citing articles Show Details

Li, Yi-jie; Xu, Cheng-ting; Lin, Dan-dan; Qin, Jiang-ke; Ye, Gao-jie; Deng, Qing-hua

Bioorganic and Medicinal Chemistry Letters, 2016 , vol. 26, # 15 p. 3425 - 3428 Title/Abstract Full Text View citing articles Show Details

6

% decrease

Active

Caco-2 cell line

1 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

5

% decrease

Active

Caco-2 cell line

10 μM

Cytoprotective

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

11.1

%

Caco-2 cell line

10 μM

Antineoplastic

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

-0.2

%

Caco-2 cell line

0.1 μM

Antineoplastic

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

3.4

%

Caco-2 cell line

1 μM

Antineoplastic

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

% decrease

15.9

%

Caco-2 cell line

10 μM

Antineoplastic

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

% decrease

17.1

%

Caco-2 cell line

1 μM

Antineoplastic

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74


Title/Abstract Full Text View citing articles Show Details

% decrease

16.2

%

Caco-2 cell line

0.1 μM

Antineoplastic

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Wang; Mateos; Goya; Amigo-Benavent; Sarriá; Bravo

Food and Chemical Toxicology, 2016 , vol. 88, p. 65 - 74 Title/Abstract Full Text View citing articles Show Details

1

% decrease

Not active

Inhibitor

Tyrosinase:Wild

3T3 cell line

Cytotoxic

Patent: EP2467134 B1, ...

Title/Abstract Full Text Show Details

Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola

Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details

1

% decrease

Not active

Inhibitor

Tyrosinase:Wild

3T3 cell line

Phototoxic

Patent: EP2467134 B1, ...

Title/Abstract Full Text Show Details

Natura Cosméticos S.A.; DA LUZ MOREIRA, Patricia; FERRARI, Cintia Rosa; TEIXEIRA TAGE BIAGGIO, Rosa Maria; SIQUEIRA JORGE, Adriano Tadeu; ARROTEIA, Kelen Fabiola

Patent: EP2467134 B1, 2016 ; Title/Abstract Full Text Show Details

4.96

CC50

11

μM

HepG 2

Cytotoxic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Aldulaimi, Omar; Uche, Fidelia I.; Hameed, Hamza; Mbye, Haddijatou; Ullah, Imran; Drijfhout, Falko; Claridge, Timothy D.W.; Horrocks, Paul; Li, Wen-Wu

Journal of Ethnopharmacology, 2017 , vol. 198, p. 221 - 225 Title/Abstract Full Text View citing articles Show Details

3.48

IC50

334.24

μM

HeLa cell line

50-400 μg/ml

Antineoplastic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Noreen, Hafiza; Farman, Muhammad; McCullagh, James S.O.

Journal of Ethnopharmacology, 2016 , vol. 194, p. 971 - 980 Title/Abstract Full Text View citing articles Show Details

4.23

IC50

58.41

μM

LN-18 cell line

50-400 μg/ml

Antineoplastic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Noreen, Hafiza; Farman, Muhammad; McCullagh, James S.O.

Journal of Ethnopharmacology, 2016 , vol. 194, p. 971 - 980 Title/Abstract Full Text View citing articles Show Details

2.63

IC50

2352.9

μM

HEK293T cell line

50-400 μg/ml

Cytotoxic

Journal of Ethnopharmaco...

Title/Abstract Full Text View citing articles Show Details

Noreen, Hafiza; Farman, Muhammad; McCullagh, James S.O.

Journal of Ethnopharmacology, 2016 , vol. 194, p. 971 - 980 Title/Abstract Full Text View citing articles Show Details

3.77

IC50

170

μM

A-375 cell line

10 nM 500 μM

Cytotoxic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details

3.82

IC50

150

μM

SK-MEL-28 cell line

10 nM 500 μM

Cytotoxic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details

3.7

IC50

200

μM

HeLa cell line

10 nM 500 μM

Cytotoxic

International Journal of...

Title/Abstract Full Text View citing articles Show Details


Esposito, Tiziana; Sansone, Francesca; Franceschelli, Silvia; Del Gaudio, Pasquale; Picerno, Patrizia; Aquino, Rita Patrizia; Mencherini, Teresa

International Journal of Molecular Sciences, 2017 , vol. 18, # 2 art. no. 392 Title/Abstract Full Text View citing articles Show Details

5

LC50

10 - 50

μM

MCF7

0.1 - 100 μM

Antineoplastic

Mechanisms of Ageing and...

Title/Abstract Full Text View citing articles Show Details

Atteya, Reham; Ashour, Mohamed E.; Ibrahim, Elsayed E.; Farag, Mohamed A.; El-Khamisy, Sherif F.

Mechanisms of Ageing and Development, 2017 , vol. 161, p. 141 - 148 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

<

15

%

MCF7

10 μM

Antineoplastic

Mechanisms of Ageing and...

Title/Abstract Full Text View citing articles Show Details

Atteya, Reham; Ashour, Mohamed E.; Ibrahim, Elsayed E.; Farag, Mohamed A.; El-Khamisy, Sherif F.

Mechanisms of Ageing and Development, 2017 , vol. 161, p. 141 - 148 Title/Abstract Full Text View citing articles Show Details

3.19

CC50

111.1

μg/ml

MDCK cell line

Cytotoxic

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Tran, Thu Thi; Kim, Meehyein; Jang, Yejin; Lee, Hye Won; Nguyen, Hoa Thi; Nguyen, Thanh Ngoc; Park, Hae Woong; Le Dang, Quang; Kim, Jin-Cheol

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 162 Title/Abstract Full Text View citing articles Show Details

% cell viability

80

%

ChaGo cell line

20 μg/ml

Antineoplastic

AAPS PharmSciTech, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Komenek, Seamkwan; Luesakul, Urarika; Ekgasit, Sanong; Vilaivan, Tirayut; Praphairaksit, Narong; Puthong, Songchan; Muangsin, Nongnuj

AAPS PharmSciTech, 2017 , vol. 18, # 4 p. 1104 - 1115 Title/Abstract Full Text View citing articles Show Details

5.25

IC50

0.96

μg/ml

peripheral lymphocyte

3.125 50 μg/ml

Antiproliferative

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

4.3

IC50

8.43

μg/ml

peripheral lymphocyte

3.125 50 μg/ml

Antiproliferative

BMC Complementary and Al...

Title/Abstract Full Text View citing articles Show Details

Yuandani; Jantan, Ibrahim; Husain, Khairana

BMC Complementary and Alternative Medicine, 2017 , vol. 17, # 1 art. no. 211 Title/Abstract Full Text View citing articles Show Details

% cell viability

100

%

RAW 264.7 cell line

100 μg/ml

Cytotoxic

Microbial Pathogenesis, ...

Title/Abstract Full Text View citing articles Show Details

Reyes, Alisha Wehdnesday Bernardo; Hong, Tae Gyu; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Lee, Kang Seok; Kim, Suk

Microbial Pathogenesis, 2017 , vol. 109, p. 86 - 93 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

KB

<= 25 μM

Antineoplastic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

BT-549 cell line

<= 25 μM

Antineoplastic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732


Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

SK-OV-3 cell line

<= 25 μM

Antineoplastic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

VERO

<= 25 μM

Cytotoxic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

LLC PK1 cell line

<= 25 μM

Cytotoxic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

SK-MEL cell line

<= 25 μM

Antineoplastic

Natural Product Research...

Title/Abstract Full Text View citing articles Show Details

Liu, Qiang; Li, Bin; Zhao, Jianping; Khan, Shabana I.; Liu, Wen-Bin; Zeng, Ting; Peng, Cai-Yun; Cai, Xiong; Peng, Qinghua; Huang, Huiyong; Khan, Ikhlas A.; Wang, Wei

Natural Product Research, 2017 , vol. 31, # 15 p. 1725 - 1732 Title/Abstract Full Text View citing articles Show Details

3.13

CC50

126.556

μg/ml

peritoneum macrophage

6.25 100 μg/ml

Cytotoxic

Naunyn-Schmiedeberg's Ar...

Title/Abstract Full Text View citing articles Show Details

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details

3.7

% Inhibition

>

50

%

1321N1 cell line

200 μM

Antineoplastic

Patent: WO2017/70052 A...

Title/Abstract Full Text Show Details

HepG 2

200 μM

Antineoplastic

Patent: WO2017/70052 A...

Title/Abstract Full Text Show Details

NPC-BM1

<= 50 μM

Antineoplastic

International Journal of...

Title/Abstract Full Text View citing articles Show Details

ONCO THERAPIES LLC; VASHISHTHA, Anshu; VASHISHTHA, Malini

Patent: WO2017/70052 A1, 2017 ; Title/Abstract Full Text Show Details

3.7

% Inhibition

>

50

%

ONCO THERAPIES LLC; VASHISHTHA, Anshu; VASHISHTHA, Malini

Patent: WO2017/70052 A1, 2017 ; Title/Abstract Full Text Show Details

1

% Inhibition

Not active

Pang, Jong-Hwei S.; Yen, Jia-Hau; Wu, Hsiao-Ting; Huang, Sheng-Teng

International Journal of Molecular Sciences, 2017 , vol. 18, # 7 art. no. 1354 Title/Abstract Full Text View citing articles Show Details

1

% Inhibition

Not active

RAW 264.7 cell line

Cytotoxic

Food and Chemical Toxico...

Title/Abstract Full Text View citing articles Show Details

Cespedes, Carlos L.; Pavon, Natalia; Dominguez, Mariana; Alarcon, Julio; Balbontin, Cristian; Kubo, Isao; El-Hafidi, Mohammed; Avila, Jose G.

Food and Chemical Toxicology, 2017 , vol. 108, p. 438 - 450 Title/Abstract Full Text View citing articles Show Details

% decrease

Low

MDA-MB231 cell line

5 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details


Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% decrease

Low

MDA-MB231 cell line

5 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% viability

34.7

%

HS 578T cell line

50 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% viability

37.6

%

MDA-MB231 cell line

50 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% viability

23.1

%

HS 578T cell line

50 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% viability

68.8

%

MCF-10F cell line

50 μmol/l

Cytotoxic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% decrease

Low

HS 578T cell line

5 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% decrease

Low

MCF-10F cell line

50 μmol/l

Cytotoxic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% decrease

Low

HS 578T cell line

5 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156 Title/Abstract Full Text View citing articles Show Details

% viability

22.6

%

MDA-MB231 cell line

50 μmol/l

Antineoplastic

Anti-Cancer Drugs, 2017 ...

Title/Abstract Full Text View citing articles Show Details

Lee, Hsiang-Lin; Lin, Chun-Shiang; Kao, Shao-Hsuan; Chou, Ming-Chih

Anti-Cancer Drugs, 2017 , vol. 28, # 10 p. 1150 - 1156


Title/Abstract Full Text View citing articles Show Details

pX

Parameter

Value (qual)

% Inhibition

Value (quant)

Unit

0

%

Action on Target

Target

Tissue/Organ

Cell

Bioassay

Dose

Effect

Reference (expand all/collapse all)

Phytotoxic

Patent: WO2017/83490 A...

Title/Abstract Full Text Show Details

Phytotoxic

Patent: WO2017/83490 A...

Title/Abstract Full Text Show Details

STEPHEN F. AUSTIN STATE UNIVERSITY; LI, Shiyou; WANG, Ping; SU, Zushang

Patent: WO2017/83490 A1, 2017 ; Title/Abstract Full Text Show Details

% Inhibition

0

%

STEPHEN F. AUSTIN STATE UNIVERSITY; LI, Shiyou; WANG, Ping; SU, Zushang

Patent: WO2017/83490 A1, 2017 ; Title/Abstract Full Text Show Details

Qualitative Information 1 of 50

2 of 50

3 of 50

4 of 50

Target

enzyme:Wild

Assay Description

Effect : |enzyme; inhib. of Bioassay : DL-mevalonate prevents decrease of cell growth caused by inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase effect of title comp. on HMG-CoA reductase determined as cell growth with or without 1 mmol/l DL-mevalonate in Eagle's minimum essential medium at 37 deg C for 24 h by photometry (absorbance at 540 nm) after staining with methylrosaniline

Results

no growth observed

Citation

Chang, Jun-Jen; Chen, Tso-Hsiao; Chan, Paul; Chen, Yi-Jen; Hsu, Feng-Lin; Lo, Ming-Yu; Lin, Jung-Yaw

Pharmacology, 2001 , vol. 62, # 4 p. 224 - 228 Title/Abstract Full Text View citing articles Show Details

Biological material

human

Assay Description

Effect : Herpes simplex virus (HSV) infection; effect on Bioassay : with Herpes simplex virus (HSV) infection Example 7 External Treatment of HSV Infection in Clinical Tests Twenty-two patients who were clinically diagnosed with HSV infection were randomly selected and divided into two groups. Acyclovir ointment and micro emulsion containing propyl gallate prepared as described in Example 1 were applied to

Results

treatment with a microemulsion containing the title compound was more effective than treatment with acyclovir; treatment with title compound-containing microemulsion gave an average time for recovery of 3 days compared with average recovery time of 5.5

Citation

QIN, Weihua

Patent: US2008/119550 A1, 2008 ; Title/Abstract Full Text Show Details

Effect

Antibiotic

Biological material

Staphylococcus aureus

Assay Description

Effect : bacterial growth; inhibition of

Results

MBIC90 > 2000 μmol/l

Citation

BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS

Patent: US2012/88671 A1, 2012 ; Title/Abstract Full Text Show Details

Effect

Apoptotic

Assay Description

Target : human promyelocytic leukemia HL-60RG cells Bioassay : further investigations with antioxidant and radical scavengers; NAC: N-acetyl-L-cysteine, antioxidant; SOD: superoxide dismutase; BAPTA-AM: intracellular Ca(2+) chelator; reference comp.: 50


μmol/l H2O2 cells were treated with title comp. for 3 or 6 h: DNA fragmentation was analysed by agarose gel electrophoresis

5 of 50

Results

title comp. induced apoptosis; effect was prevented by catalase, NAC, ascorbic acid and BAPTA-AM and was not inhibited by SOD; H2O2-induced apoptosis was prevented only by NAC, BAPTA-AM and catalase

Citation

Inoue; Sakaguchi; Isuzugawa; Tani; Ogihara

Biological and Pharmaceutical Bulletin, 2000 , vol. 23, # 10 p. 1153 - 1157 Title/Abstract Full Text View citing articles Show Details

Effect

Hepatoprotective

Assay Description

6 of 50

7 of 50

8 of 50

9 of 50

Target : ddY mouse hepatocytes Bioassay : controls: untreated cells and cells from normal mice; D-GalN (D-galactosamine, 1.0 mmol/l) and TNF-α (tumor necrosis factor-α) induced cell death; ref.: silibinin (IC50: 33.6 μmol/l); MTT: 3(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide cells cultured in William's E medium; after 2-h incubation, medium replaced with fresh medium contg. D-GalN+title comp. at various concn.; 30 min later, TNF-α (100 ng/ml) added; cell viability assessed 18 h thereafter by MTT colorimetric reaction

Results

title comp. caused 8.3, 6.6 and 6.6 percent inhibition of D-GalN/TNF-α-induced cell death at conc. of 50, 100 and 200 μmol/l, resp.; table

Citation

Adnyana, I. Ketut; Tezuka, Yasuhiro; Banskota, Arjun Hari; Tran, Kim Qui; Kadota, Shigetoshi

Biological and Pharmaceutical Bulletin, 2000 , vol. 23, # 11 p. 1328 - 1332 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

Chlorocebus aethiops VERO

Assay Description

Effect : cytotoxic confluent cell monolayer tested

Results

MNCC maximal noncytotoxic concentration 0.59 mmol/l

Citation

Tian, Li-Wen; Zhang, Ying-Jun; Qu, Chang; Wang, Yi-Fei; Yang, Chong-Ren

Journal of Natural Products, 2010 , vol. 73, # 2 p. 160 - 163 Title/Abstract Full Text View citing articles Show Details

Effect

Cell Viability

Biological material

RAW 264.7 cell line

Assay Description

Effect : cell viability RAW 264.7: macrophage-like cell line; MTT assay; MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide

Citation

Yang, Zhi-Gang; Jia, Liu-Nan; Shen, Yan; Ohmura, Atsuko; Kitanaka, Susumu

Molecules, 2011 , vol. 16, # 10 p. 8305 - 8318 Title/Abstract Full Text View citing articles Show Details

Effect

Neuroprotective

Biological material

PC12

Assay Description

Effect : H2O2-induced apotosis trypan blue exclusion method; PC12: rat pheochromocytoma cell line; cell viability rate decrease for control experiment: 52 percent

Results

cell viability rate decrease 19 percent

Citation

Crispo, James A.G.; Piche, Matthew; Ansell, Dominique R.; Eibl, Joseph K.; Tai, Isabella T.; Kumar, Aseem; Ross, Gregory M.; Tai

Biochemical and Biophysical Research Communications, 2010 , vol. 393, # 4 p. 773 - 778 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic


10 of 50

11 of 50

12 of 50

13 of 50

Biological material

human SW480 cell line

Assay Description

Effect : cell viability MTT assay

Citation

Tian, Li-Wen; Xu, Min; Li, Yan; Li, Xing-Yao; Wang, Dong; Zhu, Hong-Tao; Yang, Chong-Ren; Zhang, Ying-Jun

Chemistry and Biodiversity, 2012 , vol. 9, # 1 p. 123 - 130 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human MCF7

Assay Description

Effect : cell viability MTT assay

Citation

Tian, Li-Wen; Xu, Min; Li, Yan; Li, Xing-Yao; Wang, Dong; Zhu, Hong-Tao; Yang, Chong-Ren; Zhang, Ying-Jun

Chemistry and Biodiversity, 2012 , vol. 9, # 1 p. 123 - 130 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human A-549

Assay Description

Effect : cell viability MTT assay

Citation

Tian, Li-Wen; Xu, Min; Li, Yan; Li, Xing-Yao; Wang, Dong; Zhu, Hong-Tao; Yang, Chong-Ren; Zhang, Ying-Jun

Chemistry and Biodiversity, 2012 , vol. 9, # 1 p. 123 - 130 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

human

Assay Description

Effect : cell viability Bioassay : normal kidney proximal tubule HK-2 cells neutral red assay; trypan-blue exclusion test; confluent culture tested

Citation

Chieli, Elisabetta; Romiti, Nadia; Rodeiro, Idania; Garrido, Gabino

Chemico-Biological Interactions, 2010 , vol. 186, # 3 p. 287 - 294 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

14 of 50

Target : human promyelocytic leukemia HL-60RG cells Bioassay : cells treated with title comp. for 6 h; fluorescence micrograph taken after staining with Hoechst 33258

Results

chromatin condensation and nuclear fragmentation was observed in cells treated with title comp.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

Target : human promyelocytic leukemia HL-60RG cells Bioassay : cells treated with title comp. for 6 h; subjected to morphological examination by light microscopy


15 of 50

Results

morphological examination revealed appearance of cell shrinkage and partial chromatin condensation

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

16 of 50

Results

internucleosomal DNA cleavage of 180-200 bp multiples was observed in cells treated with title comp.; effect was prevented by W-7, BAPTA-AM, ascorbic acid, NAC, catalase, SOD and ZnSO4; fig.

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

17 of 50

morphological examination revealed appearance of cell shrinkage and partial chromatin condensation

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Target : rat hepatoma dRLh-84 cells Bioassay : cells treated with title comp. for 6 h; terminal deoxyribonucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling assay performed to detect DNA fragmentation

Results

title comp. induced apoptosis with DNA cleavage into large fragments

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

19 of 50

Target : rat hepatoma dRLh-84 cells Bioassay : cells treated with title comp. for 6 h; subjected to morphological examination by light microscopy

Results

Assay Description

18 of 50

Target : human promyelocytic leukemia HL-60RG cells Bioassay : further study with calmodulin inhibitor W-7, intracellular Ca(2+) chelator BAPTA-AM, ascorbic acid, thiol oxidant N-acetyl-L-cysteine (NAC), catalase, superoxide dismutase (SOD), Ca(2+)/Mg(2+)-dependent endonuclease inhibitor ZnSO4 cells cultured in RPMI-1640 medium; treated with title comp. for 6 h; incubated for 10 min in lysis buffer at room temp.; centrifuged, 10 min at 4 deg C; DNA isolated; DNA fragmentation analysed by agarose gel electrophoresis (agarose gel 1.5%)

Target : rat hepatoma dRLh-84 cells Bioassay : cells cultured in MEM-Eagle's salts; treated with title comp. for 6 h; incubated for 10 min in lysis buffer at room temp.; centrifuged, 10 min at 4 deg C; DNA isolated; DNA fragmentation analysed by agarose gel electrophoresis (agarose gel 1.5%)

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

Target : rat hepatoma dRLh-84 cells Bioassay : cells treated with title comp. for 6 h; fluorescence micrograph taken after staining with Hoechst 33258


20 of 50

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human PLC/PRF/5 cell line

Assay Description

21 of 50

Results

morphological examination revealed appearance of cell shrinkage and partial chromatin condensation

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human PLC/PRF/5 cell line

Assay Description

22 of 50

title comp. induced apoptosis with DNA cleavage into large fragments

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human PLC/PRF/5 cell line

Bioassay : cells cultured in RPMI-1640 medium; treated with title comp. for 6 h; incubated for 10 min in lysis buffer at room temp.; centrifuged, 10 min at 4 deg C; DNA isolated; DNA fragmentation analysed by agarose gel electrophoresis (agarose gel 1.5%)

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human PLC/PRF/5 cell line

Assay Description

24 of 50

Bioassay : cells treated with title comp. for 6 h; terminal deoxyribonucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling assay performed to detect DNA fragmentation

Results

Assay Description

23 of 50

Bioassay : cells treated with title comp. for 6 h; subjected to morphological examination by light microscopy

Bioassay : cells treated with title comp. for 6 h; fluorescence micrograph taken after staining with Hoechst 33258

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human HtTA-1 cell line

Assay Description

Bioassay : cells treated with title comp. for 6 h; subjected to morphological examination by light microscopy


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Results

morphological examination revealed appearance of cell shrinkage and partial chromatin condensation

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human HtTA-1 cell line

Assay Description

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Results

title comp. induced apoptosis with DNA cleavage into large fragments

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human HtTA-1 cell line

Assay Description

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Bioassay : cells cultured in MEM-Eagle's salt; treated with title comp. for 6 h; incubated for 10 min in lysis buffer at room temp.; centrifuged, 10 min at 4 deg C; DNA isolated; DNA fragmentation analysed by agarose gel electrophoresis (agarose gel 1.5%)

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

human HtTA-1 cell line

Assay Description

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Bioassay : cells treated with title comp. for 6 h; terminal deoxyribonucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling assay performed to detect DNA fragmentation

Bioassay : cells treated with title comp. for 6 h; fluorescence micrograph taken after staining with Hoechst 33258

Citation

Sakaguchi, Nahoko; Inoue, Makoto; Ogihara, Yukio

Biochemical Pharmacology, 1998 , vol. 55, # 12 p. 1973 - 1981 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

murine cells

Assay Description

Effect : cytotoxic

Results

cell viability 85.7 percent

Citation

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

Mus musculus

Assay Description

Effect : cytotoxic


Bioassay : monocyte macrophage RAW264.7 cells 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide-based colorimetric assay

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Citation

Manosroi, Aranya; Jantrawut, Pensak; Akazawa, Hiroyuki; Akihisa, Toshihiro; Manosroi, Jiradej

Natural Product Research, 2010 , vol. 24, # 20 p. 1915 - 1926 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

HL-60 cell line

Assay Description

Effect : cytotoxic Species : myelomonocytic HL-60 cells

Citation

Dobroslawa, Bialonska; Kasimsetty, Sashi G.; Khan, Shabana I.; Daneel, Ferreira

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 21 p. 10181 - 10186 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Biological material

Caco-2

Assay Description

Effect : enzyme activity 80% confluent culture tested; pNA: p-nitroaniline

Results

enzyme specific activity 1.9 pmol of pNA liberated/(h*μg of protein)

Citation

Forester, Sarah C.; Waterhouse, Andrew L.

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5320 - 5327 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

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Target : mouse monocyte/macrophage RAW264.7 cells Bioassay : viability of cells determined spectrophotometrically using MTT assay; viability of cells activated only with LPS/IFN-γ was arbitrally set as 100, and other results were normalized to this control in vitro; effect of title comp. on viability of cells activated with LPS/IFN-γ assayed; cells incubated with title comp. in DMEM with 10 percent FBS at 37 deg C for 1 h before, and 24 h after stimulation with LPS/IFN-γ

Results

viability of cells ( percent) / dose (μmol/l): 110/16, 108/31, 108/63, 97/125, 108/250, 20/500

Citation

Wang, Jian; Mazza

Journal of agricultural and food chemistry, 2002 , vol. 50, # 15 p. 4183 - 4189 Title/Abstract Full Text Show Details

Effect

Apoptotic

Biological material

human NCI-H460 cell line

Assay Description

Effect : reactive oxygen species production

Citation

Bin-Chuan; Hsu, Wu-Huei; Yang, Jai-Sing; Hsia, Te-Chun; Lu, Chi-Cheng; Chiang, Jo-Hua; Yang, Jiun-Long; Lin, Ching-Hsiung; Jen-jyh; Lee-jen, Wu Suen; Wellington, Gibson Wood; Chung, Jing-Gung

Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 16 p. 7596 - 7604 Title/Abstract Full Text View citing articles Show Details

Effect

Proliferative

Biological material

human HT-29

Assay Description

Effect : clonogenic efficiency


ability of the compounds to decrease clonogenic efficiency was determined by their capability to decrease colony formation compared to vehicle (DMSO 0.1%) control

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Results

percent decrese 66 percent

Citation

Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details

Effect

Proliferative

Biological material

Chlorocebus aethiops

Assay Description

Effect : cell proliferation Bioassay : kidney fibroblasts number of viable cells determined using the neutral red assay procedure

Citation

Kasimsetty, Sashi G.; Blalonska, Dobroslawa; Reddy, Muntha K.; Ma, Guoyi; Khan, Shabana I.; Ferreira, Daneel

Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 4 p. 2180 - 2187 Title/Abstract Full Text View citing articles Show Details

Effect

Antiproliferative

Assay Description

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Results

cell viability was 91.0 percent and 69.1 percent at 20 and 100 μmol/l of title comp., respectively compared to control

Citation

Kwon, Ki Han; Murakami, Akira; Ohigashi, Hajime

Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 2 p. 436 - 439 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Biological material

MCF7

Assay Description

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Bioassay : growth inhibition analysis; MTT = 3-<4,5-dimethylthiazol-2-yl>-2,5-diphenyltetrazolium bromide cell cultured in RPMI-1640 supplemented with 10 percent fetal calf serum; title comp. incubation (37 deg C, 48 h, 5 percent CO2 in air, high humidity); MTT staining; colorimetry at 570 nm

Citation

Sato, Youichi; Oketani, Hideki; Singyouchi, Kenichi; Ohtsubo, Tetsuya; Kihara, Masaru; Shibata, Hirofumi; Higuti, Tomihiko

Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 4 p. 401 - 404 Title/Abstract Full Text View citing articles Show Details

Effect

Cytoprotective

Assay Description

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Target : ICR mouse peritoneal exudate cells Bioassay : MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; control: without title comp.; DSS: dextran sulfate sodium test cells incubated with title comp. in Dulbecco's Modified Eagle Medium at 37 deg C for 30 min in 5 percent humidified CO2 atmosphere; 1 μg/ml DSS added and incubated for 12 h; cell viability measured with MTT test

Target : renal epithelial LLC-PK1 cells Bioassay : SIN-1: 3-morpholino-sydnonimine, 0.6 mmol/l; PG: pyrogallol, 0.6 mmol/l; SNP: sodium nitroprusside, 0.6 mmol/l; MTT: 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide; further studies on peroxynitrite formation cells incubated with title comp. and SIN-1 or PG or SNP for 24 h at 37 deg C, then MTT added for 4 h; absorbance read at 540 nm

Results

title comp. dose-dependently inhibited SIN-1-induced cell death, at 2.5 μg/ml cell viability: 93 percent

Citation

Yokozawa, Takako; Lee, Kyeoung Im; Nakagawa, Takako; Cho, Eun Ju; Chung, Hae Young

Pharmacy and Pharmacology Communications, 1999 , vol. 5, # 11 p. 657 - 661 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

Effect : growth Target : Escherichia coli IC188


Bioassay : parent WP2 uvrA/pKM101 bacterial strain in vitro; LA plates; paper discs impregnated with title comp. placed on solidified top agar; incubated overnight; diameter of inhibition zone determined

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Results

diameter of inhibition zone 3 mm

Citation

Martinez, A.; Urios, A.; Blanco, M.

Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details

Effect

Cytotoxic

Assay Description

Effect : growth Target : Escherichia coli IC203 Bioassay : WP2 uvrA/pKM101 bacterial strain deficient in OxyR in vitro; LA plates; paper discs impregnated with title comp. placed on solidified top agar; in the pres. and abs. of S9 mix; inhibition zone determined

Results

diameter of inhibition zone 3-18 mm; cytotoxicity of title comp. inhibited by S9

Citation

Martinez, A.; Urios, A.; Blanco, M.

Mutation research, 2000 , vol. 467, # 1 p. 41 - 53 Title/Abstract Full Text Show Details

Effect

Apoptotic

Assay Description

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Results

title comp. dose- and time-depend. induced DNA fragmentation in ladder-like pattern; effect decreased by catalase; fig.

Citation

Yang, Hsin-Ling; Chang, Wen-Huei; Chia, Yi-Chen; Huang, Chin-Jung; Lu, Fung-Jou; Hsu, Hseng-Kuang; Hseu, You-Cheng

Food and Chemical Toxicology, 2006 , vol. 44, # 12 p. 1978 - 1988 Title/Abstract Full Text View citing articles Show Details

Effect

Antiangiogenic

Biological material

zebra fish

Assay Description

Effect : intersegmental vessel growth Bioassay : embryo embryos at 24 hours post fertilization were used in assay

Citation

Zhao, Yan-Li; He, Qiu-Xia; Li, Yang; Wang, Si-Feng; Liu, Ke-Chun; Yang, Yong-Ping; Li, Xiao-Li

Molecules, 2010 , vol. 15, # 4 p. 2178 - 2186 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

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Target : human acute promyeloblastic leukemia HL-60 cells Bioassay : further invest. with vitamin C, vitamin E and catalase cells incubated with title comp. for 2-6 h; apoptosis induction studied by analysis of DNA fragmentation using 1.5% agarose gel electrophoresis; ethidium bromide staining

Target : 3T3-L1 preadipocytes BCRC 60159 Bioassay : DMEM with 10 percent FBS; humidified 5 percent CO2; 37 deg C; incubated for 6, 12, and 24 h; mitochondrial membrane potential determined

Results

title comp. induced disruption of mitochondrial membrane potential (induced apoptosis)

Citation

Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

Target : 3T3-L1 preadipocytes BCRC 60159


Bioassay : DMEM with 10 percent FBS; humidified 5 percent CO2; 37 deg C; incubated for 72 h; flow cytometric analysis of annexin V-FITC/PI double stained cells

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Results

at 50/100/250 μmol/l title comp. induced 10.0/17.0/20.6, 1.4/1.2/2.1, and 0.0/0.1/0.1 percent of early apoptosis, late apoptosis, and necrosis, respectively

Citation

Hsu, Chin-Lin; Huang, Shih-Li; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 12 p. 4191 - 4197 Title/Abstract Full Text View citing articles Show Details

Effect

Neuroprotective

Assay Description

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Results

degree of cell survival was 59.7 percent of control level; table

Citation

Mook-Jung, Inhee; Kim, Hee; Fan, Wenzhe; Tezuka, Yasuhiro; Kadota, Shigetoshi; Nishijo, Hisao; Jung, Min Whan

Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 8 p. 1101 - 1104 Title/Abstract Full Text View citing articles Show Details

Effect

Apoptotic

Assay Description

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Target : rat brain B103 neuronal cells Bioassay : control: untreated cells; MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide; cell survival expressed as percent of control (100 percent cell survival); Aβ25-35 (beta-amyloid) induce cell death with reduced cell survival of 63.5 percent 5E3 cells/well in 96-well plates in DMEM treated with title comp.; 1 h later, Aβ25-35 (25 μmol/l) added; 18 h later, MTT added; incubated at 37 deg C, 4 h; degree of cell survival detd. based on absorbance at 570-630 nm using plate reader

Target : embryo 3T3-L1 pre-adipocytes BCRC 60159 Bioassay : also pre-treated with general caspase-9 inhibitor (Z-LEHD-FMK) and caspase-3 inhibitor (Z-DEVD-FMK); HDAC: histone deacetylase cultured with title comp. for 6, 12, and 48 h; cell morphology examined after PI or DAPI staining; expression of pro- and anti-apoptotic proteins determined by Western blot analysis; expression of Caspase-3 and -9 proteins and HDAC activity assessed

Results

title comp. induced apoptosis in pre-adipocytes through Fas and mitochondrial pathway (stimulated increase in protein expression of Fas, Fasl, and p53, changed ratio of expression levels of pro- and antiapoptotic Bcl-2 family members); fig.

Citation

Hsu, Chin-Lin; Lo, Wen-Hsieh; Yen, Gow-Chin

Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 18 p. 7359 - 7365 Title/Abstract Full Text View citing articles Show Details

Effect

Cell Viability

Assay Description

Effect : cell viability Bioassay : murine peritoneal macrophages

Citation

He, Rong-Rong; Yao, Xin-Sheng; Yao, Nan; Wang, Min; Dai, Yi; Gao, Hao; Yu, Yang; Kurihara, Hiroshi

Bioscience, Biotechnology and Biochemistry, 2009 , vol. 73, # 5 p. 1129 - 1136 Title/Abstract Full Text View citing articles Show Details

Effect

Cytotoxic

Assay Description

Effect : cytotoxic Bioassay : murine macrophage-like RAW 246.7 cells

Results

cell viability > 85 percent

Citation

Kolodziej, Herbert; Radtke, Oliver A.; Kiderlen, Albrecht F.

Phytochemistry, 2008 , vol. 69, # 18 p. 3103 - 3110 Title/Abstract Full Text View citing articles Show Details

Biological material

chicken

Citation

Hsieh, Chiu-Lan; Lin, Chien-Hong; Wang, Hui-Er; Peng, Chiung-Chi; Peng, Robert Y.

Phytotherapy Research, 2015 , vol. 29, # 2 p. 267 - 280 Title/Abstract Full Text View citing articles Show Details


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Identification Physical Data Spectra Other Data

Effect

Hemolytic

Biological material

sheep erythrocyte

Citation

Alves, Michel.Muálemde.Moraes; Brito, Lucas Moreira; Souza, Adriana Cunha; Queiroz, Bárbara Cristina Silva Holanda; de Carvalho, Thaynara Parente; Batista, Joilson Ferreira; Oliveira, Jéssica.Sarade.Sousa.Macêdo.; de Mendonça, Ivete Lopes; Lira, Silvéria.Reginade.Sousa.; Chaves, Mariana Helena; Gonçalves, Juan Carlos Ramos; Carneiro, Sabrina Maria Portela; Arcanjo, Daniel Dias Rufino; Carvalho, Fernando.Aéciode.Amorim.

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017 , vol. 390, # 9 p. 893 - 903 Title/Abstract Full Text View citing articles Show Details


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