Reaxys
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Bioactivities (64)
SigmaAldrich
Reactions (473)
Substances (5)
Structure
Targets (9)
Citations (250)
N° of preparations All Preps | All Reactions
Structure/Compound Data Chemical Name: Olivetol
50 prep out of 449 reactions.
Reaxys Registry Number: 908277
CAS Registry Number: 500-66-3 Type of Substance: isocyclic Molecular Formula: C11H16O2
Linear Structure Formula: C6H3OHOHC5H11
Molecular Weight: 180.247
InChI Key: IRMPFYJSHJGOPE-UHFFFAOYSA-N
1
Available Data
Target
N° of ref.
Druglikeness
Bioactivity
Identification Physical Data (63) Spectra (24) Other Data (9)
Show Targets
245
Synthesize | Hide Details Find similar Chemical Names and Synonyms Olivetol Druglikeness Bioactivity In vitro: Efficacy (34) Quantitative Results pX
Parameter
1
% Stimulation
Value (qual) NA
Value (quant)
Unit
Action on Target Agonist
Target estrogen receptor [human]:Wild
Tissue/Organ
Cell
Bioassay Transactivation assay
Dose
Effect
Reference (expand all/collapse all) Journal of chemical info...
Title/Abstract Full Text Show Details
Gallegos Saliner, Ana; Amat, Lluis; Carbo-Dorca, Ramon; Schultz, T Wayne; Cronin, Mark T D
Journal of chemical information and computer sciences, 2003 , vol. 43, # 4 p. 1166 - 1176 Title/Abstract Full Text Show Details
4.88
IC50
13.1
µM
enzyme:Wild
In Vitro (others)
Phytochemistry, 2008 , ...
Title/Abstract Full Text View citing articles Show Details
Knoedler, Matthias; Conrad, Juergen; Wenzig, Eva M.; Bauer, Rudolf; Lacorn, Markus; Beifuss, Uwe; Carle, Reinhold; Schieber, Andreas
Phytochemistry, 2008 , vol. 69, # 4 p. 988 - 993 Title/Abstract Full Text View citing articles Show Details
4.33
IC50
46.4
µM
enzyme:Wild
In Vitro (others)
Phytochemistry, 2008 , ...
Title/Abstract Full Text View citing articles Show Details
Knoedler, Matthias; Conrad, Juergen; Wenzig, Eva M.; Bauer, Rudolf; Lacorn, Markus; Beifuss, Uwe; Carle, Reinhold; Schieber, Andreas
Phytochemistry, 2008 , vol. 69, # 4 p. 988 - 993 Title/Abstract Full Text View citing articles Show Details
1.31
pGI50
1.31
In Vitro (others)
Antiproliferative
Chemical Research in Tox...
Title/Abstract Full Text View citing articles Show Details
In Vitro (others)
Antiviral
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antiviral
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antiviral
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antineoplastic
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antineoplastic
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antineoplastic
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antineoplastic
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
Schultz, T. Wayne
Chemical Research in Toxicology, 1999 , vol. 12, # 12 p. 1262 - 1267 Title/Abstract Full Text View citing articles Show Details
4.2
IC50
63.7
µM
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
4.77
IC50
16.9
µM
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
4.65
IC50
22.5
µM
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
3.66
IC50
0.00022
M
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
3.64
IC50
0.00023
M
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
3.66
IC50
0.00022
M
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
3.7
IC50
Travis, Craig Rick
0.0002
M
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
3.7
IC50
0.0002
M
PC3
In Vitro (others)
Antineoplastic
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Cytotoxic
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Cytotoxic
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Cytotoxic
Patent: US2007/179135 ...
Title/Abstract Full Text Show Details
In Vitro (others)
Antifungal
Environmental Toxicology...
Title/Abstract Full Text View citing articles Show Details
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
4.12
TC50
75.9
µM
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
4
TC50
100
µM
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
4.11
TC50
77.5
µM
Travis, Craig Rick
Patent: US2007/179135 A1, 2007 ; Title/Abstract Full Text Show Details
4.16
LC50
6.93E05
M
Schultz, T. Wayne; Sinks, Glendon D.; Cronin, Mark T. D.
Environmental Toxicology, 2002 , vol. 17, # 1 p. 14 - 23 Title/Abstract Full Text View citing articles Show Details
3.28
Km
=
0.52
mM
CisPrenyltransferase [Streptomyces]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kumano, Takuto; Richard, Stephane B.; Noel, Joseph P.; Nishiyama, Makoto; Kuzuyama, Tomohisa
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 17 p. 8117 - 8126 Title/Abstract Full Text View citing articles Show Details
3.19
Km
=
0.64
mM
CisPrenyltransferase [Streptomyces]:Wild
Bioorganic and Medicinal...
Title/Abstract Full Text View citing articles Show Details
Kumano, Takuto; Richard, Stephane B.; Noel, Joseph P.; Nishiyama, Makoto; Kuzuyama, Tomohisa
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 17 p. 8117 - 8126 Title/Abstract Full Text View citing articles Show Details
Qualitative Information 1 of 16
2 of 16
Target
enzyme:Wild
Assay Description
Effect : enzyme activity; inhibition of Bioassay : zileuton as control leukotriene inhibition assay; test cells had 5-LOX activity; test cell suspension incubated with title comp., CaCl2, calcimycin A23187 and arachidonic acid as substrate at 37 deg C for 10 min.; concn. of LTB4 determined by competitive LTB4 EIA kit
Results
IC50 = 39.3 μM for title comp. compared with IC50 = 5.0 μM for zileuton
Citation
Knoedler, Matthias; Conrad, Juergen; Wenzig, Eva M.; Bauer, Rudolf; Lacorn, Markus; Beifuss, Uwe; Carle, Reinhold; Schieber, Andreas
Phytochemistry, 2008 , vol. 69, # 4 p. 988 - 993 Title/Abstract Full Text View citing articles Show Details
Results
antibiotic screening: acitivity against Candida albicans, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Salmonella typhimurium, Staphylococcus
aureus and S. epidermis Citation
Ayer, William A.; Browne, Lois M.; Lovell, Sarah H.
Phytochemistry (Elsevier), 1983 , vol. 22, # 10 p. 2267 - 2272 Title/Abstract Full Text View citing articles Show Details
Results
It produced a maximal inhibitory effect of about 40 percent at a dose of 2.8 E-3 M upon TPA-induced aggregation of human platelets.
Citation
Formukong; Evans
Journal of Pharmacy and Pharmacology, 1989 , vol. 41, # 10 p. 705 - 709 Title/Abstract Full Text View citing articles Show Details
4 of 16
Citation
Formukong; Evans
Journal of Pharmacy and Pharmacology, 1988 , vol. 40, # 2 p. 132 - 134 Title/Abstract Full Text View citing articles Show Details
5 of 16
Assay Description
Effect : |metabolic Target : mouse hepatic microsomes Bioassay : generated CO (reduced to CH4 or oxidized to CO2) determined by GC in vitro; microsomes from ddN mice (25 - 35 g) pretreated with phenobarbital; aerobic; 25 deg C; NADPH generating system
Results
amount of generated CO : 2.6 ppm/nmol P450
Citation
Usami; Tateoka; Watanabe; Yamamoto; Yoshimura
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 4 p. 529 - 535 Title/Abstract Full Text View citing articles Show Details
Results
cytotoxicity against KB cell ED 50 (μg/ml): 19
Citation
Arisawa; Ohmura; Kobayashi; Morita
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2431 - 2434 Title/Abstract Full Text View citing articles Show Details
Effect
Estrogen
Biological material
Saccharomyces cerevisiae
3 of 16
6 of 16
7 of 16
Assay Description
8 of 16
9 of 16
Bioassay : 17β-estradiol as positive control; ethanol as negative control in vitro Lac-Z reporter assay; seeded assay medium (ca. 5E3 yeast/ml) contain. chlorophenol red-β-Dgalactopyranoside was added to 96-well microtitre plate contain. title comp.; incub. at 30 deg C for 5 d; agitated daily; absorbency at 450 nm meas.
Citation
Schultz, T. Wayne; Sinks, Glendon D.; Cronin, Mark T. D.
Environmental Toxicology, 2002 , vol. 17, # 1 p. 14 - 23 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : enzyme activity Target : human hepatic cytochrome P450 A4 Bioassay : recombinant hepatic cytochrome P450 A4
Citation
Yamaori, Satoshi; Ebisawa, Juri; Okushima, Yoshimi; Yamamoto, Ikuo; Watanabe, Kazuhito
Life Sciences, 2011 , vol. 88, # 15-16 p. 730 - 736 Title/Abstract Full Text View citing articles Show Details
Biological material
human
10 of 16
11 of 16
12 of 16
13 of 16
14 of 16
Assay Description
Effect : enzyme activity Target : human hepatic cytochrome P450 A5 Bioassay : recombinant hepatic cytochrome P450 A5
Citation
Yamaori, Satoshi; Ebisawa, Juri; Okushima, Yoshimi; Yamamoto, Ikuo; Watanabe, Kazuhito
Life Sciences, 2011 , vol. 88, # 15-16 p. 730 - 736 Title/Abstract Full Text View citing articles Show Details
Biological material
human
Assay Description
Effect : enzyme activity Target : human hepatic cytochrome P450 A7 Bioassay : recombinant hepatic cytochrome P450 A7
Citation
Yamaori, Satoshi; Ebisawa, Juri; Okushima, Yoshimi; Yamamoto, Ikuo; Watanabe, Kazuhito
Life Sciences, 2011 , vol. 88, # 15-16 p. 730 - 736 Title/Abstract Full Text View citing articles Show Details
Target
Cannabinoid receptor 2:Wild
Substance action on target
Agonist
Assay Description
Agonistic activity of the compound towards cannabinoid receptor 2
Citation
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
Biological material
rabbit
Assay Description
Relative potency of the compound to induce convulsions in THC-SS rabbit with respect to delta 9-THC (=100)
Citation
Consroe; Martin; Schneiderman Fish
Journal of Medicinal Chemistry, 1982 , vol. 25, # 5 p. 596 - 599 Title/Abstract Full Text Show Details
Effect
inhibitory activity
Target
Calcium ATPase [human]:Wild
Substance action on target
Inhibitor
Biological material
red blood cell plasma membrane
Assay Description
Inhibition of Ca++ transporting ATPase from human erythrocyte plasma membrane upon incubation for 1 h at 37 degree C, pH 7.4
Results
Not Published
Citation
Basil Don Roufogalis; Colin Charles Duke; Qian Li
Patent: US5859067 A, 1999 ; Title/Abstract Full Text Show Details
Effect
inhibitory activity
15 of 16
16 of 16
Target
Calcium ATPase [human]:Wild
Substance action on target
Inhibitor
Biological material
red blood cell membranes
Assay Description
Inhibitory activity of compound (dissolved in DMSO) against human Ca2+-ATPase in erythrocyte membranes upon incubation in 50 mM Hepes, pH 7.4 at 37 degree C for 1 h using Microplate method
Results
Not Published
Citation
The University of Sydney
Patent: US5741821 A1, 1998 ; Title/Abstract Full Text Show Details
Effect
inhibitory activity
Target
hydrogen:potassium-exchanging ATPase:Wild
Substance action on target
Inhibitor
Assay Description
Inhibitory activity of compound against H+,K+-ATPase was measured
Results
Not Published
Citation
The University of Sydney
Patent: US5741821 A1, 1998 ; Title/Abstract Full Text Show Details
Effect
inhibitory activity
Target
sodium:potassium-exchanging ATPase:Wild
Substance action on target
Inhibitor
Assay Description
Inhibitory activity of compound against Na+/K+ ATPase was measured
Results
Not Published
Citation
The University of Sydney
Patent: US5741821 A1, 1998 ; Title/Abstract Full Text Show Details
In vivo: Animal Model (2) Quantitative Results pX
Parameter
Value (qual)
Value (quant)
Unit
Action on Target
Number
Animal Model
Biological Species
Route of administration
rabbit
intravenous administration
Journal of Medicinal Che...
Title/Abstract Full Text Show Details
rabbit
intravenous
Journal of Medicinal Che...
Dose
Dosing regimen
Effect
Reference (expand all/collapse all)
Consroe; Martin; Schneiderman Fish
Journal of Medicinal Chemistry, 1982 , vol. 25, # 5 p. 596 - 599 Title/Abstract Full Text Show Details
Number
0
administration
Title/Abstract Full Text Show Details
Consroe; Martin; Schneiderman Fish
Journal of Medicinal Chemistry, 1982 , vol. 25, # 5 p. 596 - 599 Title/Abstract Full Text Show Details
Metabolism (4) Quantitative Results pX
Parameter
5.14
IC50
Value (qual)
Value (quant)
Unit
7.21
µM
Action on Target
Target
Tissue/Organ
Cytochrome P450 2D6 [human]:Wild
Cell fraction
Cell
Substrate /Carried Molecule
Dose
Reference (expand all/collapse all)
Baculovirusinfected insect cell line
Microsome
3-[2-(N,N-diethylN-methylamino]ethyl)-7-Methoxy4methylcoumarin+3[2-(N,N-diethyl-Nmethylamino]ethyl)-7-Methoxy4-methylcoumarin
Baculovirusinfected insect cell line
Microsome
3-[2-(N,N-diethylN-methylamino]ethyl)-7-Methoxy4methylcoumarin+3[2-(N,N-diethyl-Nmethylamino]ethyl)-7-Methoxy4-methylcoumarin
0 µM
Drug Metabolism and Disp...
Title/Abstract Full Text View citing articles Show Details
Baculovirusinfected insect cell line
Microsome
Ethoxyresorufin
0 µM
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Drug Metabolism and Disp...
Title/Abstract Full Text View citing articles Show Details
Yamaori, Satoshi; Okamoto, Yasuka; Yamamoto, Ikuo; Watanabe, Kazuhito
Drug Metabolism and Disposition, 2011 , vol. 39, # 11 p. 2049 - 2056 Title/Abstract Full Text View citing articles Show Details
5.54
Ki
2.87
µM
Cytochrome P450 2D6 [human]:Wild
Yamaori, Satoshi; Okamoto, Yasuka; Yamamoto, Ikuo; Watanabe, Kazuhito
Drug Metabolism and Disposition, 2011 , vol. 39, # 11 p. 2049 - 2056 Title/Abstract Full Text View citing articles Show Details
5.52
Ki
3.04
µM
Cytochrome P450 1A1 [human]:Wild
Yamaori, Satoshi; Okushima, Yoshimi; Masuda, Kazufumi; Kushihara, Mika; Katsu, Takashi; Narimatsu, Shizuo; Yamamoto, Ikuo; Watanabe, Kazuhito
Biological and Pharmaceutical Bulletin, 2013 , vol. 36, # 7 p. 1197 - 1203 Title/Abstract Full Text View citing articles Show Details
4.86
IC50
13.8
µM
Cytochrome P450 1A1 [human]:Wild
Baculovirusinfected insect cell line
Microsome
Ethoxyresorufin
0 µM
Biological and Pharmaceu...
Title/Abstract Full Text View citing articles Show Details
Yamaori, Satoshi; Okushima, Yoshimi; Masuda, Kazufumi; Kushihara, Mika; Katsu, Takashi; Narimatsu, Shizuo; Yamamoto, Ikuo; Watanabe, Kazuhito
Biological and Pharmaceutical Bulletin, 2013 , vol. 36, # 7 p. 1197 - 1203 Title/Abstract Full Text View citing articles Show Details
Toxicity/Safety Pharmacology (24) Quantitative Results pX
Parameter
3.65
IC50
Value (qual)
Value (quant)
Unit
40
µg/mL
Action on Target
Target
Tissue/Organ
Dose
Effect
Reference (expand all/collapse all)
Cell
Bioassay
SNB-75
Cell/tumor cell: proliferation/viability/growth
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
DLD I
Cell/tumor cell: proliferation/viability/growth
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
3.63
IC50
42
Immugen Pharmaceuticals Inc.
µg/mL
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
3.74
IC50
33
µg/mL
NCI H23
Cell/tumor cell: proliferation/viability/growth
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
ZR 75.1
Cell/tumor cell: proliferation/viability/growth
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
LOXIMVI
Cell/tumor cell: proliferation/viability/growth
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
PC-3
Cell/tumor cell: proliferation/viability/growth
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
caki I
Cell/tumor cell: proliferation/viability/growth
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
monocyte
Viral infection
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
monocyte
Viral infection
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
peripheral blood mononuclear cell
Viral infection
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
peripheral blood mononuclear cell
Viral infection
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
U-1
Viral infection
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
3.7
IC50
36
µg/mL
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
3.61
IC50
44
µg/mL
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
3.69
IC50
37
µg/mL
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
3.65
IC50
40
µg/mL
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
4.2
IC50
63.7
µM
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
4.12
IC50
75.9
µM
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
4.77
IC50
16.9
µM
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
1
IC50
>
100
µM
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
4.65
IC50
22.5
µM
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
4.11
IC50
77.5
µM
U-1
Viral infection
Patent: US6274635 B1, ...
Title/Abstract Full Text Show Details
Immugen Pharmaceuticals Inc.
Patent: US6274635 B1, 2001 ; Title/Abstract Full Text Show Details
3.15
MIC
128
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Appendino, Giovanni; Gibbons, Simon; Giana, Anna; Pagani, Alberto; Grassi, Gianpaolo; Stavri, Michael; Smith, Eileen; Rahman, M. Mukhlesur
Journal of Natural Products, 2008 , vol. 71, # 8 p. 1427 - 1430 Title/Abstract Full Text View citing articles Show Details
3.45
MIC
64
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Appendino, Giovanni; Gibbons, Simon; Giana, Anna; Pagani, Alberto; Grassi, Gianpaolo; Stavri, Michael; Smith, Eileen; Rahman, M. Mukhlesur
Journal of Natural Products, 2008 , vol. 71, # 8 p. 1427 - 1430 Title/Abstract Full Text View citing articles Show Details
3.45
MIC
64
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Appendino, Giovanni; Gibbons, Simon; Giana, Anna; Pagani, Alberto; Grassi, Gianpaolo; Stavri, Michael; Smith, Eileen; Rahman, M. Mukhlesur
Journal of Natural Products, 2008 , vol. 71, # 8 p. 1427 - 1430 Title/Abstract Full Text View citing articles Show Details
3.45
MIC
64
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Appendino, Giovanni; Gibbons, Simon; Giana, Anna; Pagani, Alberto; Grassi, Gianpaolo; Stavri, Michael; Smith, Eileen; Rahman, M. Mukhlesur
Journal of Natural Products, 2008 , vol. 71, # 8 p. 1427 - 1430 Title/Abstract Full Text View citing articles Show Details
3.45
MIC
64
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Appendino, Giovanni; Gibbons, Simon; Giana, Anna; Pagani, Alberto; Grassi, Gianpaolo; Stavri, Michael; Smith, Eileen; Rahman, M. Mukhlesur
Journal of Natural Products, 2008 , vol. 71, # 8 p. 1427 - 1430 Title/Abstract Full Text View citing articles Show Details
3.45
MIC
64
µg/mL
Cell/tumor cell: proliferation/viability/growth
Antibiotic
Journal of Natural Produ...
Title/Abstract Full Text View citing articles Show Details
Appendino, Giovanni; Gibbons, Simon; Giana, Anna; Pagani, Alberto; Grassi, Gianpaolo; Stavri, Michael; Smith, Eileen; Rahman, M. Mukhlesur
Journal of Natural Products, 2008 , vol. 71, # 8 p. 1427 - 1430 Title/Abstract Full Text View citing articles Show Details
1
LC50
>
100
µM
Patent: US5859067 A, 1...
Title/Abstract Full Text Show Details
Basil Don Roufogalis; Colin Charles Duke; Qian Li
Patent: US5859067 A, 1999 ; Title/Abstract Full Text Show Details
pX
Parameter
Value (qual)
Value (quant)
Unit
1
LC50
>
18
µg/mL
Patent: US5859067 A, 1...
Title/Abstract Full Text Show Details
µM
Patent: US5741821 A1, ...
Action on Target
Target
Tissue/Organ
Cell
Bioassay
Dose
Effect
Reference (expand all/collapse all)
Basil Don Roufogalis; Colin Charles Duke; Qian Li
Patent: US5859067 A, 1999 ; Title/Abstract Full Text Show Details
1
LC50
>
100
Title/Abstract Full Text Show Details
The University of Sydney
Patent: US5741821 A1, 1998 ; Title/Abstract Full Text Show Details
Qualitative Information 1 of 2
2 of 2
Biological material
Tetrahymena pyriformis
Assay Description
Toxicity was measured as population growth impairment to Tetrahymena pyriformis
Citation
Schultz, T. Wayne
Chemical Research in Toxicology, 1999 , vol. 12, # 12 p. 1262 - 1267 Title/Abstract Full Text View citing articles Show Details
Biological material
Tetrahymena pyriformis
Assay Description
Ciliate toxicity of the compound in Tetrahymena pyriformis
Citation
Schueuermann, Gerrit; Aptula, Aynur O.; Kuehne, Ralph; Ebert, Ralf-Uwe
Chemical Research in Toxicology, 2003 , vol. 16, # 8 p. 974 - 987 Title/Abstract Full Text View citing articles Show Details
Identification Physical Data Spectra Other Data Chemical Name: 1,3-dihydroxy-5-[5'-(2H3)-pentyl]benzene Reaxys Registry Number: 1970018
CAS Registry Number: 58545-61-2 Type of Substance: isocyclic Molecular Formula: C11H16O2
Linear Structure Formula: C11H13(2)H3O2
2
14 prep out of 16 reactions.
Druglikeness
Identification Physical Data (3) Spectra (7)
Show Targets
4
1 prep out of 1 reactions.
Druglikeness
Identification
Show Targets
1
Molecular Weight: 183.223
InChI Key: IRMPFYJSHJGOPE-FIBGUPNXSA-N
Synthesize | Show Details Find similar Chemical Name: 5-n-Amylresorcin-<4,6-14C> Reaxys Registry Number: 1970044
CAS Registry Number: 34818-58-1 Type of Substance: isocyclic Molecular Formula: C11H16O2
Linear Structure Formula: C9(14)C2H16O2
3
Molecular Weight: 184.225
InChI Key: IRMPFYJSHJGOPE-DEKVXHJQSA-N
Synthesize | Show Details Find similar Chemical Name: 3H-Olivetol Reaxys Registry Number: 2453685
CAS Registry Number: 38228-31-8 Type of Substance: isocyclic Molecular Formula: C11H16O2
Linear Structure Formula: C11H14T2O2
Molecular Weight: 184.231
InChI Key: IRMPFYJSHJGOPE-WNNBQYHSSA-N
4
1 prep out of 1 reactions.
Druglikeness
Identification
Show Targets
1
4 prep out of 6 reactions.
Druglikeness
Identification Physical Data (1) Spectra (5)
Show Targets
2
Synthesize | Show Details Find similar Chemical Name: 1,3-dihydroxy-5-[4'-(2H2)-5'-(2H3)-pentyl]benzene Reaxys Registry Number: 9333775
CAS Registry Number: 504396-87-6 Type of Substance: isocyclic Molecular Formula: C11H16O2
Linear Structure Formula: C11H11(2)H5O2
Molecular Weight: 185.207
InChI Key: IRMPFYJSHJGOPE-ZBJDZAJPSA-N
5
Synthesize | Show Details Find similar