2-(2,5-Dimethoxyphenyl)acetonitrile [C10H11NO2]

Page 1

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Bioactivities (193)

Yield

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SigmaAldrich

Reactions (18)

Substances (24)

Targets (4)

Citations (16)

Conditions

References

1

Synthesize Find similar 80%

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Rx-ID: 25932751 Find similar reactions

With sodium azide; TEA; triethylphosphine; (bis-(2-methoxyethyl)amino)sulfur trufluoride in dichloromethane; dimethyl sulfoxide

T=0°C; 50 h;

A

2

Kangani, Cyrous O.; Day, Billy W.; Kelley, David E.

Tetrahedron Letters, 2008 , vol. 49, # 5 p. 914 - 918 Title/Abstract Full Text View citing articles Show Details

B

C


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Rx-ID: 4839290 Find similar reactions

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Kosynkin, Dmitry; Bockman, T. Michael; Kochi, Jay K.

Journal of the Chemical Society. Perkin Transactions 2, 1997 , # 10 p. 2003 - 2012 Title/Abstract Full Text View citing articles Show Details

in acetonitrile

8 h;

A

B

C

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3

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Rx-ID: 4839291 Find similar reactions

C: 32%

Kosynkin, Dmitry; Bockman, T. Michael; Kochi, Jay K.

Journal of the Chemical Society. Perkin Transactions 2, 1997 , # 10 p. 2003 - 2012 Title/Abstract Full Text View citing articles Show Details

in acetonitrile

8 h;

A

B

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4

Synthesize Find similar Rx-ID: 7455824 Find similar reactions

8 h;

5

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Kosynkin, Dmitry; Bockman, T. Michael; Kochi, Jay K.

Journal of the Chemical Society. Perkin Transactions 2, 1997 , # 10 p. 2003 - 2012 Title/Abstract Full Text View citing articles Show Details


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88%

6

Kitagawa; Kawaguchi; Inoue; Katayama

Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 3030 - 3033 Title/Abstract Full Text View citing articles Show Details

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Rx-ID: 20345628 Find similar reactions

Multi-step reaction with 2 steps 1: 96 percent / hydroxylamine / ethanol / 1 h / Ambient temperature 2: 88 percent / 1,1'-carbonyldiimidazole / benzene / 1.) r.t., 15 min, 2.) 68-70 deg C, 1 h View Scheme

Kitagawa; Kawaguchi; Inoue; Katayama

Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 3030 - 3033 Title/Abstract Full Text View citing articles Show Details

A

B

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Rx-ID: 3738180 Find similar reactions

Rx-ID: 3072325 Find similar reactions

With 1,1'-carbonyldiimidazole in benzene

1.) r.t., 15 min, 2.) 68-70 deg C, 1 h;

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7

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A: 81% B: 12%

With ethoxyethoxyethanol; sodium amide in 1,2-dimethoxyethane

1.) 45 deg C, 2 h, 2.) -10 deg C, 2 h, 3.) -30 deg C, 2 h;

Carre, M. C.; Ezzinadi, A. S.; Zouaoui, M. A.; Geoffroy, P.; Caubere, P.

Synthetic Communications, 1989 , vol. 19, # 19 p. 3323 - 3330 Title/Abstract Full Text Show Details


8

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Rx-ID: 3738179 Find similar reactions

9

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Han, Yu Xin; Jovanovic, Misa V.; Biehl, Edward R.

Journal of Organic Chemistry, 1985 , vol. 50, # 8 p. 1334 - 1337 Title/Abstract Full Text View citing articles Show Details

With potassium amide

1.) liq. NH3, 2.) 1 h; Yield given. Multistep reaction;

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Rx-ID: 2893559 Find similar reactions

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16.3%

in acetonitrile

Irradiation; Mechanism;

Kurz, M. E.; Lapin, S. C.; Miriam, K.; Hagen, T. J.; Qian, X. Q.

Journal of Organic Chemistry, 1984 , vol. 49, p. 2728 - 2733 Title/Abstract Full Text View citing articles Show Details

16.3%

in acetonitrile

Irradiation;

Kurz, M. E.; Lapin, S. C.; Miriam, K.; Hagen, T. J.; Qian, X. Q.

Journal of Organic Chemistry, 1984 , vol. 49, p. 2728 - 2733 Title/Abstract Full Text View citing articles Show Details

16.3%

in acetonitrile

22 h; Irradiation;

Lapin, Stephen; Kurz, Michael E.

Journal of the Chemical Society, Chemical Communications, 1981 , # 16 p. 817 - 818 Title/Abstract Full Text View citing articles Show Details

10

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Find similar Rx-ID: 2117510 Find similar reactions

Find similar

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With sodium iodide in dimethyl sulfoxide

T=90°C; 16 h; Yield given;

Parker; Kallmerten

Journal of Organic Chemistry, 1980 , vol. 45, # 13 p. 2614 - 2620 Title/Abstract Full Text View citing articles Show Details

11

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Rx-ID: 21200355 Find similar reactions

Multi-step reaction with 2 steps 1: HCl / benzene 2: NaI / dimethylsulfoxide / 16 h / 90 °C View Scheme

Parker; Kallmerten

Journal of Organic Chemistry, 1980 , vol. 45, # 13 p. 2614 - 2620 Title/Abstract Full Text View citing articles Show Details

Multi-step reaction with 2 steps 1: pyridine; SOCl2

View Scheme

Harley-Mason; Jackson

Journal of the Chemical Society, 1954 , p. 1165,1168 Full Text View citing articles Show Details

12

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Rx-ID: 21229680 Find similar reactions

Multi-step reaction with 3 steps 1: NaBH4 / ethanol / 0 °C 2: HCl / benzene 3: NaI / dimethylsulfoxide / 16 h / 90 °C View Scheme

Parker; Kallmerten

Journal of Organic Chemistry, 1980 , vol. 45, # 13 p. 2614 - 2620 Title/Abstract Full Text View citing articles Show Details

Multi-step reaction with 3 steps 1: platinum; ethanol / Hydrogenation 2: pyridine; SOCl2

View Scheme

Harley-Mason; Jackson

Journal of the Chemical Society, 1954 , p. 1165,1168 Full Text View citing articles Show Details


13

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Rx-ID: 7190558 Find similar reactions

Moore; Capaldi

Journal of Organic Chemistry, 1964 , vol. 29, p. 2860 Full Text View citing articles Show Details

Kalra et al.

Indian Journal of Chemistry, 1967 , vol. 5, p. 287,289 Full Text Show Details

Farkas; Varady

Acta Chimica Academiae Scientiarum Hungaricae, 1963 , vol. 38, p. 283,285 Full Text Show Details

Dirania

Chemistry and Industry (London, United Kingdom), 1977 , p. 278 Full Text Show Details

Farkas; Varady

Magyar Kemiai Folyoirat, 1963 , vol. 69, # 10 p. 458,459-460 Chem.Abstr., 1964 , vol. 60, # 7980c Full Text Show Details

14

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Rx-ID: 290781 Find similar reactions

Green et al.

Journal of the Chemical Society, 1959 , p. 3362,3369 Full Text View citing articles Show Details

15

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Rx-ID: 595832 Find similar reactions


With ethanol

Harley-Mason; Jackson

Journal of the Chemical Society, 1954 , p. 1165,1168 Full Text View citing articles Show Details

With 1,4-dioxane

Green et al.

Journal of the Chemical Society, 1959 , p. 3362,3369 Full Text View citing articles Show Details

16

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Rx-ID: 22334132 Find similar reactions

Multi-step reaction with 2 steps 1: dibenzoyl peroxide; CCl4; N-bromo-succinimide View Scheme

Green et al.

Journal of the Chemical Society, 1959 , p. 3362,3369 Full Text View citing articles Show Details

17

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Rx-ID: 341851 Find similar reactions

Harley-Mason; Jackson

Journal of the Chemical Society, 1954 , p. 1165,1168 Full Text View citing articles Show Details

18

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Rx-ID: 483145 Find similar reactions

Sugasawa; Shigehara


Chemische Berichte, 1941 , vol. 74, p. 459,462 Full Text View citing articles Show Details


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