Etizolam [C17H15ClN4S]

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6 reactions in Reaxys

2018-05-20 18h:52m:05s (UTC)

S Cl

1. Query N N N

N

Search as: Product, As drawn, No mixtures ) AND (IDE.XRN=572740))

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S

S Cl

Cl

N

N

N

N N

N

NH

N

Rx-ID: 897979 View in Reaxys 1/6 Yield

Conditions & References With potassium permanganate in acetone, Ambient temperature Weber,K.-H. et al.; Justus Liebigs Annalen der Chemie; (1978); p. 1257 - 1265 View in Reaxys

Cl

O

O

S

O

Cl

N

N N N

S

N

N H 2N

NH

Rx-ID: 1175400 View in Reaxys 2/6 Yield

Conditions & References With acetic acid in benzene Tahara; Araki; Shiroki; Matsuo; Munakata; Arzneimittel-Forschung/Drug Research; vol. 28; nb. 7; (1978); p. 1153 - 1158 View in Reaxys

Cl

S Cl

N

N N

S S

N

N

N H

Rx-ID: 22452647 View in Reaxys 3/6 Yield

Conditions & References Reaction Steps: 2 1: N2H4*H2O / methanol / Ambient temperature 2: AcOH / benzene With hydrazine hydrate, acetic acid in methanol, benzene Tahara; Araki; Shiroki; Matsuo; Munakata; Arzneimittel-Forschung/Drug Research; vol. 28; nb. 7; (1978); p. 1153 - 1158 View in Reaxys

Copyright © 2018 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.

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2018-05-20 18:53:16


Cl

S Cl

N

N N N

S O

N

N H

Rx-ID: 22455519 View in Reaxys 4/6 Yield

Conditions & References Reaction Steps: 3 1: P2S5, Py / 1 h / 80 °C 2: N2H4*H2O / methanol / Ambient temperature 3: AcOH / benzene With pyridine, tetraphosphorus decasulfide, hydrazine hydrate, acetic acid in methanol, benzene Tahara; Araki; Shiroki; Matsuo; Munakata; Arzneimittel-Forschung/Drug Research; vol. 28; nb. 7; (1978); p. 1153 - 1158 View in Reaxys

Cl

Br

S Cl

N N

N

N N N

S

N

Cl

Rx-ID: 22719596 View in Reaxys 5/6 Yield

Conditions & References Reaction Steps: 2 1: NH3 / methanol 2: KMnO4 / acetone / Ambient temperature With potassium permanganate, ammonia in methanol, acetone Weber,K.-H. et al.; Justus Liebigs Annalen der Chemie; (1978); p. 1257 - 1265 View in Reaxys

S Cl

N N N

N

Rx-ID: 5904300 View in Reaxys 6/6 Yield

Conditions & References 2-Hydrazino-5-o-chlorphenyl-7-ethyl-3H-thieno-<2,3-e>-<1,4>-diazepin, Ethylorthoacetat Patent; Yoshitomi Pharm.; DE2229845; (1972); ; vol. 78; nb. 84416 View in Reaxys 2-Hydrazino-5-o-chlorphenyl-7-ethyl-3H-thieno-<2,3-e>-<1,4>-diazepin, Acetimino-ethylether*HCl Patent; Yoshitomi Pharm.; DE2229845; (1972); ; vol. 78; nb. 84416 View in Reaxys 2-Hydrazino-5-o-chlorphenyl-7-ethyl-3H-thieno-<2,3-e>-<1,4>-diazepin, Acetamidin*HCl/3-Methylimidazol

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Patent; Yoshitomi Pharm.; DE2229845; (1972); ; vol. 78; nb. 84416 View in Reaxys 2-Hydrazino-5-o-chlorphenyl-7-ethyl-3H-thieno-<2,3-e>-<1,4>-diazepin, Acetamidin*HCl/2-Methylimidazol; 195gradC Patent; Yoshitomi Pharm.; DE2229845; (1972); ; vol. 78; nb. 84416 View in Reaxys 2-Hydrazino-5-o-chlorphenyl-7-ethyl-3H-thieno-<2,3-e>-<1,4>-diazepin, Thioacetamid/H2SO4 Patent; Yoshitomi Pharm.; DE2229845; (1972); ; vol. 78; nb. 84416 View in Reaxys 2-Hydrazino-5-o-chlorphenyl-7-ethyl-3H-thieno-<2,3-e>-<1,4>-diazepin, Ac2O; 205gradC Patent; Yoshitomi Pharm.; DE2229845; (1972); ; vol. 78; nb. 84416 View in Reaxys 2-Hydrazino-5-o-chlorphenyl-7-ethyl-3H-thieno-<2,3-e>-<1,4>-diazepin, AcCl, PPS/150gradC Patent; Yoshitomi Pharm.; DE2229845; (1972); ; vol. 78; nb. 84416 View in Reaxys entspr. 5,6-Dihydro-triazolo-diazepin, Brom Patent; C.H. Boehringer Sohn; FR2318165; (1977); DE2531677; (1977); ; vol. 86; nb. 171521 View in Reaxys entspr. 5,6-Dihydro-triazolo-diazepin, KMnO4 Patent; C.H. Boehringer Sohn; FR2318165; (1977); DE2531677; (1977); ; vol. 86; nb. 171521 View in Reaxys Aus dem entspr. Dihydrodiazepin Patent; Boehringer; DE2533924; (1977); ; vol. 86; nb. 171518 View in Reaxys 2-(1-Amino-aethylidenhydrazino)-5-(2-chlorphenyl-7-aethyl-3H-thieno<2,3-e>-1,4-diazepin, Δ (195grad) Patent; Iosilomi Seijaku; JP515397; (1976); Ref. Zh., Khim.; vol. 3; nb. O150; (1977) View in Reaxys

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