1.2 1-(benzo[d][1,3]dioxol-5-yl)propan-1-one to 1-(benzo[d][1,3]dioxol-5-yl)-2-'halo'propan-1

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Query Query O O

O

O

O

1. Query

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2 reactions in Reaxys

2016-03-23 09h:22m:40s (EST)

O

X

Search as: As drawn, No salts, No mixtures

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O

O

O

O

O

O

Br

Rx-ID: 166783 View in Reaxys 1/2 Yield 82 %

Conditions & References With bromine in diethyl ether, Time= 0.5h, Inert atmosphere Lou, Sha; Fu, Gregory C.; Journal of the American Chemical Society; vol. 132; (2010); p. 1264 - 1266 View in Reaxys With dichloromethane, bromine Patent; Winthrop Chem. Co.; US1964973; (1932) View in Reaxys With tetrachloromethane, bromine Ohara; Yakugaku Zasshi; vol. 71; (1951); p. 1244; ; (1952); p. 5552 View in Reaxys With bromine, acetic acid Shapiro; Journal of Organic Chemistry; vol. 15; (1950); p. 1027,1032 View in Reaxys O

O

O

O

O

O

Cl

Rx-ID: 5261935 View in Reaxys 2/2 Yield 66 %

Conditions & References With lithium chloride in N,N-dimethyl-formamide, Time= 6h, T= 80 °C , Chlorination Zacchino, Susana A.; Lopez, Silvia N.; Pezzenati, German D.; Furlan, Ricardo L.; Santecchia, Carina B.; Munoz, Lorena; Giannini, Fernando A.; Rodriguez, Ana M.; Enriz, Ricardo D.; Journal of Natural Products; vol. 62; nb. 10; (1999); p. 1353 - 1357 View in Reaxys

Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.

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2016-03-23 09:27:25


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