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Date
3 substances in Reaxys
2016-06-08 13h:21m:46s (EST)
Cl
N
1. Query N
Search as: As drawn
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Reaxys ID 4908925 View in Reaxys
1/3 CAS Registry Number: 147429-37-6 Chemical Name: 1-(3-chlorophenyl)-4-phenethylpiperazine Linear Structure Formula: C18H21ClN2 Molecular Formula: C18H21ClN2 Molecular Weight: 300.831 Type of Substance: heterocyclic InChI Key: NKMGWZZAFWDLFG-UHFFFAOYSA-N Note:
Cl
N N
Substance Label (1) Label References 3
Motel, William C.; Healy, Jason R.; Viard, Eddy; Pouw, Buddy; Martin, Kelly E.; Matsumoto, Rae R.; Coop, Andrew; Bioorganic and Medicinal Chemistry Letters; vol. 23; nb. 24; (2013); p. 6920 - 6922, View in Reaxys
Derivative (1) Derivative
References
1-(3-Chloro-phe- Glennon; Yousif; Ismaiel; El-Ashmawy; Herndon; Fischer; Server; Howie; Journal of Medicinal Chemisnyl)-4-phenethyl- try; vol. 34; nb. 12; (1991); p. 3360 - 3365, View in Reaxys piperazine; hydrochloride Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
Bioactivities present
Patent; Virginia Commonwealth University; US6057371; (2000); (A1) English, View in Reaxys; Glennon; Yousif; Ismaiel; El-Ashmawy; Herndon; Fischer; Server; Howie; Journal of Medicinal Chemistry; vol. 34; nb. 12; (1991); p. 3360 - 3365, View in Reaxys; Motel, William C.; Healy, Jason R.; Viard, Eddy; Pouw, Buddy; Martin, Kelly E.; Matsumoto, Rae R.; Coop, Andrew; Bioorganic and Medicinal Chemistry Letters; vol. 23; nb. 24; (2013); p. 6920 6922, View in Reaxys
Reaxys ID 4894981 View in Reaxys
2/3 Cl
N
Cl
CAS Registry Number: 136534-45-7 Linear Structure Formula: C18H21ClN2*ClH Molecular Formula: C18H21ClN2*ClH Molecular Weight: 337.292 Type of Substance: heterocyclic InChI Key: ZQYRRYIDCGSIHY-UHFFFAOYSA-N Note:
H
N
Substance Label (1) Label References 21
Glennon; Yousif; Ismaiel; El-Ashmawy; Herndon; Fischer; Server; Howie; Journal of Medicinal Chemistry; vol. 34; nb. 12; (1991); p. 3360 - 3365, View in Reaxys
Melting Point (1) 1 of 1
Melting Point [°C]
197 - 198
Solvent (Melting Point)
butan-2-one
Comment (Melting Point)
Crystallization with 1 Mol(s) H2O
Glennon; Yousif; Ismaiel; El-Ashmawy; Herndon; Fischer; Server; Howie; Journal of Medicinal Chemistry; vol. 34; nb. 12; (1991); p. 3360 - 3365, View in Reaxys Pharmacological Data (2) 1 of 2
Comment (Pharmacological Data)
Bioactivities present
Glennon; Yousif; Ismaiel; El-Ashmawy; Herndon; Fischer; Server; Howie; Journal of Medicinal Chemistry; vol. 34; nb. 12; (1991); p. 3360 - 3365, View in Reaxys
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2 of 2
Comment (Pharmacological Data)
affinity to σ receptors (guinea pig brain)
Glennon; Yousif; Ismaiel; El-Ashmawy; Herndon; Fischer; Server; Howie; Journal of Medicinal Chemistry; vol. 34; nb. 12; (1991); p. 3360 - 3365, View in Reaxys
Reaxys ID 24650197 View in Reaxys
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Cl
Chemical Name: 1-(3-chlorophenyl)-4-phenethylpiperazine oxalate Linear Structure Formula: C18H21ClN2*C2H2O4 Molecular Formula: C2H2O4*C18H21ClN2 Molecular Weight: 390.867 InChI Key: HXEQQCPERCBCDO-UHFFFAOYSA-N Note:
HO N N
O O OH
Melting Point (1) 1 of 1
Melting Point [°C]
210 - 212
Location
supporting information
Motel, William C.; Healy, Jason R.; Viard, Eddy; Pouw, Buddy; Martin, Kelly E.; Matsumoto, Rae R.; Coop, Andrew; Bioorganic and Medicinal Chemistry Letters; vol. 23; nb. 24; (2013); p. 6920 - 6922, View in Reaxys Mass Spectrometry (1) Description (Mass Location Spectrometry)
References
electrospray ionisation (ESI); spectrum
Motel, William C.; Healy, Jason R.; Viard, Eddy; Pouw, Buddy; Martin, Kelly E.; Matsumoto, Rae R.; Coop, Andrew; Bioorganic and Medicinal Chemistry Letters; vol. 23; nb. 24; (2013); p. 6920 - 6922, View in Reaxys
supporting information
Pharmacological Data (2) 1 of 2
Comment (Pharmacological Data)
Bioactivities present
Motel, William C.; Healy, Jason R.; Viard, Eddy; Pouw, Buddy; Martin, Kelly E.; Matsumoto, Rae R.; Coop, Andrew; Bioorganic and Medicinal Chemistry Letters; vol. 23; nb. 24; (2013); p. 6920 - 6922, View in Reaxys 2 of 2
Comment (Pharmacological Data)
physiological behaviour discussed
Motel, William C.; Healy, Jason R.; Viard, Eddy; Pouw, Buddy; Martin, Kelly E.; Matsumoto, Rae R.; Coop, Andrew; Bioorganic and Medicinal Chemistry Letters; vol. 23; nb. 24; (2013); p. 6920 - 6922, View in Reaxys
Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.
3/3
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