Query Query
Results
Date
15 reactions in Reaxys
2016-06-08 10h:29m:55s (EST)
H N NH 2
1. Query
Search as: As drawn
Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.
1/6
2016-06-08 10:39:02
N
H 2N
H 2N
H N
Rx-ID: 357906 View in Reaxys 1/15 Yield
Conditions & References With ethanol, platinum, Hydrogenation Biel et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 2805,2810, 2813 View in Reaxys With ethanol, acetic acid, platinum, Hydrogenation Biel et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 2805,2810, 2813 View in Reaxys With hydrogenchloride, platinum, Hydrogenation Biel et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 2805,2810, 2813 View in Reaxys
O
H 2N
H N
Rx-ID: 4411790 View in Reaxys 2/15 Yield
Conditions & References (i) N2H4*H2O, EtOH, (ii) H2, PtO2, Pd-C, Multistep reaction Anderson,F.E. et al.; Journal of Medicinal and Pharmaceutical Chemistry; vol. 5; nb. 2; (1962); p. 221 - 230 View in Reaxys Reaction Steps: 2 1: N2H4+H2O; methanol 2: platinum; ethanolic HCl / Hydrogenation With hydrogenchloride, methanol, hydrazine hydrate, platinum Biel et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 2805,2810, 2813 View in Reaxys
HN
O
H
H 2N
H N H
NH
NH O
Rx-ID: 820692 View in Reaxys 3/15 Yield
Conditions & References With hydrogenchloride Bernstein et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 4433 View in Reaxys
Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.
2/6
2016-06-08 10:39:02
H N
H 2N
H N
N
Rx-ID: 3581198 View in Reaxys 4/15 Yield
Conditions & References With hydrogenchloride in ethanol, Time= 15h, T= 25 °C , Yield given Baldwin, Jack E.; Adlington, Robert M.; Newington, Ian M.; Journal of the Chemical Society, Chemical Communications; nb. 2; (1986); p. 176 - 178 View in Reaxys
H 2N
N O
H N H
NH
NH O
Rx-ID: 22190188 View in Reaxys 5/15 Yield
Conditions & References Reaction Steps: 2 1: NaBH4; aqueous methanol 2: aqueous HCl With hydrogenchloride, methanol, sodium tetrahydroborate Bernstein et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 4433 View in Reaxys
O
H 2N
H N H
Rx-ID: 22204897 View in Reaxys 6/15 Yield
Conditions & References Reaction Steps: 3 2: NaBH4; aqueous methanol 3: aqueous HCl With hydrogenchloride, methanol, sodium tetrahydroborate Bernstein et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 4433 View in Reaxys
aq.-ethanolic KOH
H 2N
H N
Br
Rx-ID: 19033412 View in Reaxys 7/15 Yield
Conditions & References Reaction Steps: 3 1: 99 percent 2: trifluoroacetic acid / 25 °C 3: conc. aq. HCl / ethanol / 15 h / 25 °C With hydrogenchloride, trifluoroacetic acid in ethanol
Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.
3/6
2016-06-08 10:39:02
Baldwin, Jack E.; Adlington, Robert M.; Newington, Ian M.; Journal of the Chemical Society, Chemical Communications; nb. 2; (1986); p. 176 - 178 View in Reaxys
NE
H 2N
H N
N
Rx-ID: 19051148 View in Reaxys 8/15 Yield
Conditions & References Reaction Steps: 2 1: trifluoroacetic acid / 25 °C 2: conc. aq. HCl / ethanol / 15 h / 25 °C With hydrogenchloride, trifluoroacetic acid in ethanol Baldwin, Jack E.; Adlington, Robert M.; Newington, Ian M.; Journal of the Chemical Society, Chemical Communications; nb. 2; (1986); p. 176 - 178 View in Reaxys
Br
H N
H 2N
Rx-ID: 30840086 View in Reaxys 9/15 Yield
Conditions & References With hydrazine in ethanol, Time= 24h, Reflux Radi, Marco; Dreassi, Elena; Brullo, Chiara; Crespan, Emmanuele; Tintori, Cristina; Bernardo, Vincenzo; Valoti, Massimo; Zamperini, Claudio; Daigl, Henry; Musumeci, Francesca; Carraro, Fabio; Naldini, Antonella; Filippi, Irene; Maga, Giovanni; Schenone, Silvia; Botta, Maurizio; Journal of Medicinal Chemistry; vol. 54; nb. 8; (2011); p. 2610 - 2626 View in Reaxys
O
H 2N
O
H
Cl
Na +
S
H 2N
H N
N–
H
Rx-ID: 357601 View in Reaxys 10/15 Yield
Conditions & References Biel et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 4995 View in Reaxys
H 2N
N O
H N
N
O
Rx-ID: 892984 View in Reaxys 11/15 Yield
Conditions & References With hydrogenchloride Yashunskii,V.G.; Vasil'eva,V.G.; J. Gen. Chem. USSR (Engl. Transl.); vol. 30; (1960); p. 2754 - 2756,2736 - 2738 View in Reaxys
Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.
4/6
2016-06-08 10:39:02
H 2N
H N
Rx-ID: 978238 View in Reaxys 12/15 Yield
Conditions & References (i) NaNHNH2, (ii) H2O, Multistep reaction Kauffmann,T. et al.; Chemische Berichte; vol. 98; (1965); p. 904 - 911 View in Reaxys
H 2N
H N
Rx-ID: 6047577 View in Reaxys 13/15 Yield
Conditions & References PhCH2COCH3, 1.) Hydrazinhydrat, 2.) H2 an PtO2 Patent; Lakeside Labs., Inc.; GB863158; (1957); US; (1956); ; vol. 56; nb. 14168f; (1962) View in Reaxys Phenylaceton-(N'-acetylhydrazon) / H2,Pt Franguesa-Graner; Galenica Acta; vol. 14; nb. 2; (1961); p. 81,82-89; ; nb. 27166; (1961) View in Reaxys Acetylhydrazin 2, NaOH Patent; Chugai Pharm.; JP13972; (1960); ; vol. 59; nb. 9802f; (1963) View in Reaxys PhCH2Ac, 1.) N2H4*H2O, 2.) H2-PtO2 Patent; Colgate-Palmolive; US3334017; (1956); ; vol. 68; nb. 12676s; (1968) View in Reaxys 3-Phenylpropylidenhydrazin, kat. Hydrierung Patent; Colgate; US3359316; (1958); ; vol. 69; nb. 10210g; (1968) View in Reaxys RNH2(R= C6H5-CH2-CH(CH3)-)1.Monochloressigsaeureethylester-->R-NH-CH2-COOEt 2.NaOH 3.HCl->RNHCH2COOH*HCl 4.HNO2-->RN(NO)CH2COOH 5.Ac2O-->/BRN= 971586/ 6.wss.HCl-->RNHNH2*HCl 6.wss.Na2CO3-->RNHNH2 Iffland et al.; Journal of the American Chemical Society; vol. 83; (1961); p. 747,748 View in Reaxys RNH2(R= C6H5-CH2-CH(CH3)-)1.Monobromessigsaeureethylester-->R-NH-CH2-COOEt 2.NaOH 3.HCl->RNHCH2COOH*HCl 4.HNO2-->RN(NO)CH2COOH 5.Ac2O-->/BRN= 971586/ 6.wss.HCl-->RNHNH2*HCl 6.wss.Na2CO3-->RNHNH2 Iffland et al.; Journal of the American Chemical Society; vol. 83; (1961); p. 747,748 View in Reaxys 2-Hydrazono-1-phenylpropan in Eg.+ A./H2,Pt Patent; Lakeside Labor.; US2978461; (1958); ; nb. 25861; (1961) View in Reaxys Phenylaceton 1.Hydrazinhydrat,Me. 2.H2,Pt,A. Patent; Lakeside Labor.; US3000903; (1959); ; vol. 56; nb. 1393; (1962) View in Reaxys
Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.
5/6
2016-06-08 10:39:02
H 2N
H N H
Rx-ID: 8096343 View in Reaxys 14/15 Yield
Conditions & References /BRN= 3197504/ Bernstein et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 4433 View in Reaxys Biel et al.; Journal of the American Chemical Society; vol. 81; (1959); p. 4995 View in Reaxys Patent; BASF SE; US2012/123155; (2012); (A1) English View in Reaxys
H 2N
H N
14CH
Rx-ID: 5964092 View in Reaxys 15/15 Yield
Conditions & References 2-Phenylisopropyl-1-14C-glutamylhydrazin/konz.wss.HCl(100grad) Eberson; Acta Chemica Scandinavica (1947-1973); vol. 17; (1963); p. 2349 View in Reaxys
Copyright © 2016 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.
6/6
2016-06-08 10:39:02