Reaxys
PubChem
eMolecules
Reactions (34)
Yield
Substances (4)
Citations (50)
Conditions
References
1
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Rx-ID: 41209452 Find similar reactions
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93%
With camphor-10-sulfonic acid in water
T=100°C; 16 h; Green chemistry;
Shen, Guanshuo; Zhou, Haifeng; Du, Peng; Liu, Sensheng; Zou, Kun; Uozumi, Yasuhiro
RSC Advances, 2015 , vol. 5, # 104 p. 85646 - 85651 Title/Abstract Full Text View citing articles Show Details
73%
With iron(III) chloride hexahydrate in water
T=100°C; 24 h; Green chemistry; Hide Experimental Procedure
Shen, Guanshuo; Zhou, Haifeng; Sui, Yuebo; Liu, Qixing; Zou, Kun
Tetrahedron Letters, 2016 , vol. 57, # 5 p. 587 - 590 Title/Abstract Full Text View citing articles Show Details
2. Typical Procedure for the Synthesis of 2-Substitued Quinazolinones General procedure: A flask was charged with 2-aminobenzamide (1a; 27.2 mg, 0.2 mmol), pentane-2,4-dione (2A;30.0 mg, 0.3 mmol), FeCl3·6H2O (10.8 mg, 0.04 mmol), and PEG-400/H2O (1.0 mL, 1:9 (v/v)).The reaction was stirred at 100 °C for 24 h. When the reaction was complete monitored by TLC,the mixture was cooled to room temperature, extracted with EtOAc (3×20 mL). The combined organic phase was washed with water, dried over anhydrous Na2SO4, filtered, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to give the product 3aA (29.3 mg, 91percent) as white solid.
2
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Rx-ID: 42319858 Find similar reactions
Multi-step reaction with 3 steps 1: ammonium chloride; zinc / tetrahydrofuran; water / 20 °C 2: L-Tartaric acid; N,N'-Dimethylurea / 90 °C / |Green chemistry 3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.5 h / 20 °C / |Green chemistry View Scheme
Ghosh, Suman Kr; Nagarajan, Rajagopal
RSC Advances, 2016 , vol. 6, # 33 p. 27378 - 27387 Title/Abstract Full Text View citing articles Show Details
3
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Rx-ID: 42319869 Find similar reactions
Multi-step reaction with 2 steps 1: L-Tartaric acid; N,N'-Dimethylurea / 90 °C / |Green chemistry 2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.5 h / 20 °C / |Green chemistry View Scheme
Ghosh, Suman Kr; Nagarajan, Rajagopal
RSC Advances, 2016 , vol. 6, # 33 p. 27378 - 27387 Title/Abstract Full Text View citing articles Show Details
Multi-step reaction with 2 steps 1: copper(I) oxide; PCy3 / chloroform / 24 h / 100 °C / |Schlenk technique; |Sealed tube 2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / chloroform / 1 h / 20 °C / |Schlenk technique; |Sealed tube View Scheme
Xu, Wei; Zhu, Xiao-Rui; Qian, Peng-Cheng; Zhang, Xing-Guo; Deng, Chen-Liang
Synlett, 2016 , vol. 27, # 20 art. no. ST-2016-W0432-L, p. 2851 - 2857 Title/Abstract Full Text Show Details
4
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With 2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane
T=20°C; 0.5 h; Green chemistry;
Rx-ID: 42319876 Find similar reactions
Ghosh, Suman Kr; Nagarajan, Rajagopal
RSC Advances, 2016 , vol. 6, # 33 p. 27378 - 27387 Title/Abstract Full Text View citing articles Show Details
40 mg
With 2,3-dicyano-5,6-dichloro-p-benzoquinone in chloroform
T=20°C; 1 h; Schlenk techniqueSealed tube; Hide Experimental Procedure
Xu, Wei; Zhu, Xiao-Rui; Qian, Peng-Cheng; Zhang, Xing-Guo; Deng, Chen-Liang
Synlett, 2016 , vol. 27, # 20 art. no. ST-2016-W0432-L, p. 2851 - 2857 Title/Abstract Full Text Show Details
2-Methyl-3-phenylquinazolin-4(3H)-one (3); Typical Procedure General procedure: A reaction tube was charged under air with 2-aminobenzanilide(1a, 0.2 mmol), Et3N (2a, 0.6 mmol), Cu2O (10 molpercent), PCy3(10 molpercent), and CHCl3 (2 mL). The vessel was sealed, heated at100 °C (oil-bath temperature) for 24 h, and then cooled to r.t.DDQ (1 equiv) was added, and the mixture was kept at r.t. for 1h. After filtration of the mixture and evaporation of the solventunder reduced pressure, the crude product was purified by column chromatography [silica gel, hexane–EtOAc (3:1)] to givea light-yellow solid; yield: 42.0 mg (89percent);
5
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Multi-step reaction with 5 steps 1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 3 h / 0 - 20 °C 2: triethylamine / dichloromethane 3: ammonium chloride; zinc / tetrahydrofuran; water / 20 °C 4: L-Tartaric acid; N,N'-Dimethylurea / 90 °C / |Green chemistry 5: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.5 h / 20 °C / |Green chemistry View Scheme
Rx-ID: 42319889 Find similar reactions
Ghosh, Suman Kr; Nagarajan, Rajagopal
RSC Advances, 2016 , vol. 6, # 33 p. 27378 - 27387 Title/Abstract Full Text View citing articles Show Details
6
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Multi-step reaction with 4 steps 1: triethylamine / dichloromethane 2: ammonium chloride; zinc / tetrahydrofuran; water / 20 °C 3: L-Tartaric acid; N,N'-Dimethylurea / 90 °C / |Green chemistry 4: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.5 h / 20 °C / |Green chemistry View Scheme
A
7
Rx-ID: 42319902 Find similar reactions
Ghosh, Suman Kr; Nagarajan, Rajagopal
RSC Advances, 2016 , vol. 6, # 33 p. 27378 - 27387 Title/Abstract Full Text View citing articles Show Details
B
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Multi-step reaction with 3 steps 1: phosphorus trichloride / toluene / 20 h / 80 - 120 °C / |Inert atmosphere 2: palladium diacetate; sodium tetrahydroborate; (R)-DTBM-SEGPHOS / N,N-dimethyl-formamide / 21 h / 0 °C / |Inert atmosphere 3: palladium diacetate; 1,3-bis-(diphenylphosphino)propane; potassium phosphate / 1,4-dioxane / 22 h / 45 °C View Scheme
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Hirai, Motohiro; Terada, Shumpei; Yoshida, Hiroaki; Ebine, Kenki; Hirata, Tomoaki; Kitagawa, Osamu
Organic Letters, 2016 , vol. 18, # 21 p. 5700 - 5703 Title/Abstract Full Text Show Details
A
B
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8
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Multi-step reaction with 3 steps 1: phosphorus trichloride / toluene / 20 h / 80 - 120 °C / |Inert atmosphere 2: palladium diacetate; sodium tetrahydroborate; (R)-DTBM-SEGPHOS / N,N-dimethyl-formamide / 21 h / 0 °C / |Inert atmosphere 3: palladium diacetate; 1,3-bis-(diphenylphosphino)propane; potassium phosphate / 1,4-dioxane / 22 h / 45 °C View Scheme
Hirai, Motohiro; Terada, Shumpei; Yoshida, Hiroaki; Ebine, Kenki; Hirata, Tomoaki; Kitagawa, Osamu
Organic Letters, 2016 , vol. 18, # 21 p. 5700 - 5703 Title/Abstract Full Text Show Details
A
B
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9
Synthesize Find similar Rx-ID: 44592713 Find similar reactions
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A: 40%
With potassium phosphate; 1,3-bis-(diphenylphosphino)propane; palladium diacetate in 1,4-dioxane
T=45°C; 22 h;
Hirai, Motohiro; Terada, Shumpei; Yoshida, Hiroaki; Ebine, Kenki; Hirata, Tomoaki; Kitagawa, Osamu
Organic Letters, 2016 , vol. 18, # 21 p. 5700 - 5703 Title/Abstract Full Text Show Details
A
B
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10
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Multi-step reaction with 2 steps 1: palladium diacetate; sodium tetrahydroborate; (R)-DTBM-SEGPHOS / N,N-dimethyl-formamide / 0 °C 2: palladium diacetate; 1,3-bis-(diphenylphosphino)propane; potassium phosphate / 1,4-dioxane / 22 h / 45 °C View Scheme
Hirai, Motohiro; Terada, Shumpei; Yoshida, Hiroaki; Ebine, Kenki; Hirata, Tomoaki; Kitagawa, Osamu
Organic Letters, 2016 , vol. 18, # 21 p. 5700 - 5703 Title/Abstract Full Text Show Details
11
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Rx-ID: 9941356 Find similar reactions
12
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81%
With sulfuric acid; silica gel
T=80°C; 4 h;
Salehi, Peyman; Dabiri, Minoo; Zolfigol, Mohammad Ali; Baghbanzadeh, Mostafa
Tetrahedron Letters, 2005 , vol. 46, # 41 p. 7051 - 7053 Title/Abstract Full Text View citing articles Show Details
68%
in neat (no solvent) T=120°C; 4 h; Green chemistry; Temperature;
Kumar, Dinesh; Jadhavar, Pradeep S.; Nautiyal, Manesh; Sharma, Himanshu; Meena, Prahlad K.; Adane, Legesse; Pancholia, Sahaj; Chakraborti, Asit K.
RSC Advances, 2015 , vol. 5, # 39 p. 30819 - 30825 Title/Abstract Full Text View citing articles Show Details
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Rx-ID: 37474998 Find similar reactions
Stage #1: With triphenylphosphine in toluene
Aza-Wittig Reaction; 0.166667 h; Stage #2: With titanium(IV) isopropylate; 1,1,3,3-tetramethyldisiloxane in toluene
T=110°C;
Wang, Long; Wang, Ying; Chen, Min; Ding, Ming-Wu
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 5 p. 1098 - 1104 Title/Abstract Full Text View citing articles Show Details
13
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Rx-ID: 25257538 Find similar reactions
78%
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With acetic anhydride in pyridine; methanol
The Sherwin-Williams Company
Patent: US3989698 A1, 1976 ;
Hide Experimental Procedure
Title/Abstract Full Text Show Details
29:EXAMPLE 29
EXAMPLE 29 The reaction of isatoic anhydride with acetic anhydride in pyridine was carried out in the manner described for the preparation of 2-methyl-4H-3,1-benzoxazine-4-one. The reaction mixture was cooled to room temperature and the o-toluidine added all at once. The reaction mixture was stirred at room temperature for 16 hours. The solvent was distilled off under reduced pressure. The residue, 11.5 parts was analyzed by NMR. The NMR spectrum showed that 95percent of the crude reaction product was 2-methyl-3-(o-tolyl)-quinazoline-4-one. The crude reaction product was crystallized from 25 ml of methanol to give 9.7 parts (78percent yield) of 2-methyl-3-(o-tolyl)-quinazoline-4-one with m.p. 113°-115° C. Fang, Jie; Zhou, Jianguang
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 12 p. 2389 - 2391 Title/Abstract Full Text View citing articles Show Details
Multi-step reaction with 2 steps 1: ethanol / 20 h / Reflux 2: [{(η5-C5Me5)IrCl}2(μ-Cl)2] / 24 h / 150 °C / Inert atmosphere; Sealed tube View Scheme
14
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Rx-ID: 32651626 Find similar reactions
Multi-step reaction with 2 steps 1: copper(l) iodide; caesium carbonate; (2S,4R)-2-carboxy-4-hydroxypyrrolidine / N,N-dimethyl-formamide / 24 h / 80 °C / Inert atmosphere 2: 1,1,1,3,3,3-hexamethyl-disilazane; zinc(II) chloride / N,N-dimethyl-formamide / 4 h / 20 °C View Scheme
Xu, Lanting; Jiang, Yongwen; Ma, Dawei
Organic Letters, 2012 , vol. 14, # 4 p. 1150 - 1153 Title/Abstract Full Text View citing articles Show Details
15
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With 1,1,1,3,3,3-hexamethyl-disilazane; zinc(II) chloride in N,N-dimethyl-formamide
T=20°C; 4 h;
Rx-ID: 32651653 Find similar reactions
Xu, Lanting; Jiang, Yongwen; Ma, Dawei
Organic Letters, 2012 , vol. 14, # 4 p. 1150 - 1153 Title/Abstract Full Text View citing articles Show Details
16
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Rx-ID: 32786214 Find similar reactions
97%
With [{(η5-C5Me5)IrCl}2(μ-Cl)2] T=150°C; 24 h; Inert atmosphereSealed tube;
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Fang, Jie; Zhou, Jianguang
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 12 p. 2389 - 2391 Title/Abstract Full Text View citing articles Show Details
17
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Rx-ID: 5492257 Find similar reactions
Hydra Biosciences, Inc.
Patent: US2007/179164 A1, 2007 ; Location in patent: Page/Page column 53 ; Title/Abstract Full Text Show Details
BOLTZE; DELL; LEHWALD; LORENZ; RUEBERG-SCHWEER
Arzneimittel-Forschung, 1963 , vol. 13, p. 688 - 701 Title/Abstract Full Text View citing articles Show Details
Klosa
Journal fuer Praktische Chemie (Leipzig), 1961 , vol. 14, p. 84 Full Text Show Details
Andrisano; Chiesi
Ateneo Parmense, 1961 , vol. 32, p. 671 Chem.Abstr., 1963 , vol. 58, # 3428c Full Text Show Details
Soliman
Synthesis, 1979 , vol. No 10, p. 803 - 804 Title/Abstract Full Text View citing articles Show Details
Grammaticakis
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1961 , vol. 252, p. 4011 Full Text Show Details
Moehrle; Seidel
Archiv der Pharmazie (Weinheim, Germany), 1976 , vol. 309, p. 471,473,478 Full Text View citing articles Show Details
Orgamol
Patent: GB982207 , 1965 ; Chem.Abstr., 1965 , vol. 62, # 16268e Full Text Show Details
Hans Starke
Patent: DD35123 , 1962 ; Chem.Abstr., 1965 , vol. 63, # 8377d Full Text Show Details
Chinoin Gyog. es Veg. Termekek Gyara Rt.
Patent: HU149660 , 1960 ; Chem.Abstr., 1963 , vol. 58, # 4585d Full Text Show Details
The Sherwin-Williams Co.(USA)
Patent: FR2301524DE2556590 , 1976 ; Chem.Abstr., vol. 85, # 160115z Full Text Show Details
Stroh
Patent: DD65928 , 1968 ; Chem.Abstr., 1969 , vol. 71, # 124485x Full Text Show Details
Warner Lambert Pharm. Co.
Patent: GB1114920 , 1966 ; Chem.Abstr., 1968 , vol. 69, # 59274v Full Text Show Details
Nord. Droge and Kem. AIS
Patent: NL295501 , 1965 ; Chem.Abstr., 1965 , vol. 63, # 18113g Full Text Show Details
Petyunin; Kozhevnikov
Meditsinskaya Promyshlennost SSSR, 1966 , vol. 20, # 4 p. 13,14,15 Chem.Abstr., 1966 , vol. 65, # 7176b Full Text Show Details
Soliman; Shafik; Elnenaey
Journal of Pharmaceutical Sciences, 1978 , vol. 67, # 3 p. 411 - 413 Title/Abstract Full Text View citing articles Show Details
Errede et al.
Journal of Organic Chemistry, 1976 , vol. 41, p. 1765 Full Text View citing articles Show Details
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
Patent: HU150883 , 1962 ; Chem.Abstr., 1964 , vol. 60, # 6855c Full Text Show Details
Klosa
Journal fuer Praktische Chemie (Leipzig), 1963 , vol. 20, p. 283 Full Text Show Details
General Anilin and Film Corp.
Patent: US3213094 , 1963 ; Chem.Abstr., 1966 , vol. 64, # 2107b Full Text Show Details
Manhas; Amin; Rao
Synthesis, 1977 , vol. No. 5, p. 309 - 310 Title/Abstract Full Text View citing articles Show Details
Gronowitz et al.
Acta Pharmaceutica Suecica, 1968 , vol. 5, p. 563,567,570 Full Text View citing articles Show Details
Pesson; Richer
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1968 , vol. 266, p. 1787 Full Text Show Details
Petjunin; Koshewnikow
Biol. Akt. Soedin., 1965 , p. 152,153,154,155 Full Text Show Details
0.1 g (8%)
Hide Experimental Procedure
Research Corporation
Patent: US4183931 A1, 1980 ; Title/Abstract Full Text Show Details
6:2-(2-Hydroxy-2-phenylethyl)-3-o-tolyl-4(3H)-quinazolinone
Continued elution with hexane-ether (80:20) afforded 0.1 g (8percent) of recovered methaqualone, mp 114°-115°, mmp 114°-114°. The 1 H NMR spectrum was identical with an authentic sample of methaqualone.
18
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Rx-ID: 9544927 Find similar reactions
72%
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With trimethylaluminum in n-heptane; 1,2-dichloro-ethane
18 h; Heating;
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Jeong, Jae Uk; Chen, Xiaohong; Rahman, Attiq; Yamashita, Dennis S.; Luengo, Juan I.
Organic Letters, 2004 , vol. 6, # 6 p. 1013 - 1016 Title/Abstract Full Text View citing articles Show Details
19
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Rx-ID: 4719456 Find similar reactions
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With trichlorophosphate
Heating;
Shivarama Holla; Akberali; Shivananda
Bollettino Chimico Farmaceutico, 1996 , vol. 135, # 5 p. 351 - 354 Title/Abstract Full Text View citing articles Show Details
With acetic acid
Heating;
Welch; Ewing; Huang; Menniti; Pagnozzi; Kelly; Seymour; Guanowsky; Guhan; Guinn; Critchett; Lazzaro; Ganong; DeVries; Staigers; Chenard
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 2 p. 177 - 181 Title/Abstract Full Text View citing articles Show Details
20
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Rx-ID: 15180065 Find similar reactions
Multi-step reaction with 2 steps 1: AcOH / Heating 2: AcOH / Heating View Scheme
Welch; Ewing; Huang; Menniti; Pagnozzi; Kelly; Seymour; Guanowsky; Guhan; Guinn; Critchett; Lazzaro; Ganong; DeVries; Staigers; Chenard
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 2 p. 177 - 181 Title/Abstract Full Text View citing articles Show Details
21
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Multi-step reaction with 2 steps 1: Heating 2: POCl3 / Heating View Scheme
Rx-ID: 17209174 Find similar reactions
Shivarama Holla; Akberali; Shivananda
Bollettino Chimico Farmaceutico, 1996 , vol. 135, # 5 p. 351 - 354 Title/Abstract Full Text View citing articles Show Details
22
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Rx-ID: 777178 Find similar reactions
66%
23
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With phosphorus trichoride in toluene
3 h; Heating;
Wolfe, James F.; Rathman, Terry L.; Sleevi, Mark C.; Campbell, James A.; Greenwood, Thomas D.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 161 - 166 Title/Abstract Full Text View citing articles Show Details
With toluene; phosphorus trichoride
Kacker; Zaheer
Journal of the Indian Chemical Society, 1951 , vol. 28, p. 344 Full Text Show Details
Serventi; Marchesi
Bollettino Scientifico della Facolta di Chimica Industriale di Bologna, 1957 , vol. 15, p. 114 Full Text Show Details
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Rx-ID: 3866201 Find similar reactions
53%
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With phosphorus pentoxide; N,N-dimethylcyclohexylamine hydrochloride in water
T=180°C; 0.416667 h;
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Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468 Title/Abstract Full Text Show Details
A
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C
D
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24
Synthesize Find similar Rx-ID: 3134533 Find similar reactions
Pohlmann; Theil; Otto
Pharmazie, 1986 , vol. 41, # 6 p. 390 - 394 Title/Abstract Full Text View citing articles Show Details
in hexane
Irradiation;
A
B
C
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25
Synthesize Find similar Rx-ID: 3134534 Find similar reactions
in hexane
Ambient temperaturefurther solvents, irradiation; Product distribution;
Pohlmann; Theil; Otto
Pharmazie, 1986 , vol. 41, # 6 p. 390 - 394 Title/Abstract Full Text View citing articles Show Details
A
26
B
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Rx-ID: 1719945 Find similar reactions
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Pohlmann; Theil; Pfeifer
Pharmazie, 1985 , vol. 40, # 4 p. 269 - 269 Title/Abstract Full Text View citing articles Show Details
3 h; Heating;
A
B
C
D
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27
Synthesize Find similar Rx-ID: 3848199 Find similar reactions
in methanol
1.83333 h; Irradiationphotochemical decomposition, λ=366 nm, other wave-lenghts: 254 nm, sun light (280-800 nm);
Theil; Pohlmann; Pfeifer; Franke
Pharmazie, 1985 , vol. 40, # 5 p. 328 - 331 Title/Abstract Full Text View citing articles Show Details
28
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Rx-ID: 2093537 Find similar reactions
Mannschreck; Koller; Stuhler; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 381 - 383 Title/Abstract Full Text View citing articles Show Details
29
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Rx-ID: 2093538 Find similar reactions
Mannschreck; Koller; Stuhler; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 381 - 383 Title/Abstract Full Text View citing articles Show Details
30
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Rx-ID: 3196133 Find similar reactions
Mannschreck; Koller; Stuhler; et al.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 381 - 383 Title/Abstract Full Text View citing articles Show Details
T=135°C; ΔG(excit.); Thermodynamic dataRate constant;
A
B
C
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31
Synthesize Find similar Rx-ID: 2853160 Find similar reactions
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A: 42% B: 25% C: 5%
With diisopropylamine in tetrahydrofuran; hexane
1 h;
Rathman, Terry L.; Sleevi, Mark C.; Krafft, Marie E.; Wolfe, James F.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2169 - 2176 Title/Abstract Full Text View citing articles Show Details
A: 42% B: 25% C: 5%
With diisopropylamine in tetrahydrofuran; hexane
1 h;
Rathman, Terry L.; Sleevi, Mark C.; Krafft, Marie E.; Wolfe, James F.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2169 - 2176 Title/Abstract Full Text View citing articles Show Details
With diisopropylamine in tetrahydrofuran; hexane
1 h;
Rathman, Terry L.; Sleevi, Mark C.; Krafft, Marie E.; Wolfe, James F.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2169 - 2176 Title/Abstract Full Text View citing articles Show Details
32
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Rx-ID: 3810210 Find similar reactions
84%
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With N,N-dimethyl-cyclohexylamine; phosphorus pentoxide
T=180°C; 0.75 h;
Nielsen, Knud Erik; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1980 , vol. 34, # 9 p. 637 - 642 Title/Abstract Full Text Show Details
A
B
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33
A: 0.65 g (52%)
Rx-ID: 25287318 Find similar reactions
Research Corporation
Patent: US4183931 A1, 1980 ;
Hide Experimental Procedure
Title/Abstract Full Text Show Details
4:C.
Final elution of the column with hexane-ether (1:1) yielded 0.65 g (52percent) of recovered methaqualone, mp 112.5°-114°. The 1 H NMR spectrum was identical with that of an authentic sample of methaqualone. No monosulfenylated derivative of methaqualone could be isolated.
34
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Rx-ID: 6113309
Find similar Anthranilsaeure, Hexadeutero-acetanhydrid;
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Bogentoft; Ericsson; Danielsson
Acta Pharmaceutica Suecica, 1974 , vol. 11, # 6 p. 513 - 522 Title/Abstract Full Text View citing articles Show Details