N-(1-(benzo[d][1,3]dioxol-5-yl)propan-2-yl)hydroxylamine (MDOH)

Page 1

Reaxys

PubChem

eMolecules

Reactions (4)

Yield

Substances (5)

Citations (5)

Conditions

References

1

Synthesize Find similar 76%

2

Synthesize Find similar

Stage #1: With hydroxylamine in methanol

T=20°C; 0.5 h; Stage #2: With hydrogenchloride; sodium cyanoborohydride in methanol

T=20°C; pH=4 - 6; 72 h; Further stages.;

Rx-ID: 11228290 Find similar reactions

Montgomery; Buon; Eibauer; Guiry; Keenan; McBean British Journal of Pharmacology, 2007 , vol. 152, # 7 p. 1121 - 1130 Title/Abstract Full Text View citing articles Show Details


Synthesize Find similar 31%

Synthesize Find similar

Rx-ID: 1835356 Find similar reactions

With hydroxylamine; sodium cyanoborohydride

Braun; Shulgin

Arzneimittel-Forschung, 1980 , vol. 30, # 5 p. 825 - 830 Title/Abstract Full Text View citing articles Show Details

With hydroxylamine hydrochloride; sodium cyanoborohydride in methanol

72 h; Ambient temperature;

De Boer; Tan; Gorter; Van de Wal; Kettenes-van den Bosch; De Bruijn; Maes

Journal of Mass Spectrometry, 1997 , vol. 32, # 11 p. 1236 - 1246 Title/Abstract Full Text View citing articles Show Details

Multi-step reaction with 2 steps 1: 51 percent / hydroxylamine hydrochloride, pyridine / ethanol / 2 h / Heating 2: NaBH3CN, aq. HCl / methanol / 72 h / Ambient temperature View Scheme

Braun; Shulgin

Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 2 p. 192 - 195 Title/Abstract Full Text View citing articles Show Details

3

Synthesize Find similar

Synthesize Find similar

Rx-ID: 1978664 Find similar reactions

With hydrogenchloride; sodium cyanoborohydride in methanol

72 h; Ambient temperature;

Braun; Shulgin

Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 2 p. 192 - 195 Title/Abstract Full Text View citing articles Show Details

A

B

C

Synthesize Find similar

Synthesize Find similar

Synthesize Find similar

4

Synthesize Find similar Rx-ID: 1802480 Find similar reactions

With rabbit liver cytochrome P450IIB4; 1,2-dilauroylphosphatidylcholine; NADPH; NADPH-cytochrome P450 reductase; ascorbic acid powder in water

T=37°C; 0.0833333 h; other (methylenedioxy)phenyl compounds; also in the hydroxyl radical system (ferric chloride, EDTA, potassium phosphate buffer, pH 7.4); demethylenation reaction; Mechanism;

Fukuto; Kumagai; Cho

Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2871 - 2876 Title/Abstract Full Text View citing articles Show Details


Turn static files into dynamic content formats.

Create a flipbook
Issuu converts static files into: digital portfolios, online yearbooks, online catalogs, digital photo albums and more. Sign up and create your flipbook.