N-(1-phenylpropan-2-yl)hydroxylamine (N-HydroxyAmph)

Page 1

Reaxys

PubChem

eMolecules

Reactions (13)

Yield

Substances (7)

Citations (14)

Conditions

References

1

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2

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Rx-ID: 1986969 Find similar reactions

74%

With sodium tetrahydroborate; borane-THF in tetrahydrofuran

Kabalka, George W.; Laila Guindi; Varma, Rajender S.

Tetrahedron, 1990 , vol. 46, # 21 p. 7443 - 7457 Title/Abstract Full Text View citing articles Show Details

74%

With sodium tetrahydroborate; borane-THF in tetrahydrofuran

2 h;

Mourad, M. Soubei; Varma, Rajender S.; Kabalka, George W.

Journal of Organic Chemistry, 1985 , vol. 50, # 1 p. 133 - 135 Title/Abstract Full Text View citing articles Show Details


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Rx-ID: 668823 Find similar reactions

With hydrogenchloride; sodium cyanoborohydride in tetrahydrofuran; methanol

T=20°C; 3 h;

Cashman, John R.; Xiong, Yeng N.; Lifen, Xu; Janowsky, Aaron

Journal of Pharmacology and Experimental Therapeutics, 1999 , vol. 288, # 3 p. 1251 - 1260 Title/Abstract Full Text View citing articles Show Details

With hydrogenchloride; platinum

Hydrogenation;

Gilsdorf; Nord

Journal of the American Chemical Society, 1952 , vol. 74, p. 1837,1841 Full Text View citing articles Show Details

With hydrogenchloride; hydrogen; platinum(IV) oxide in ethanol

Benington,F. et al.

Journal of Medicinal Chemistry, 1965 , vol. 8, p. 100 - 104 Full Text View citing articles Show Details

With sodium cyanoborohydride in methanol

pH=3;

Hanquet, Gilles; Lusinchi, Xavier

Tetrahedron, 1994 , vol. 50, # 42 p. 12185 - 12200 Title/Abstract Full Text View citing articles Show Details

With sodium cyanoborohydride in tetrahydrofuran; acetic acid

T=20°C; Reduction; 24 h;

Katritzky, Alan R.; Cui, Xilin; Long, Qiuhe; Yang, Baozhen; Wilcox, Allan L.; Zhang, Yong-Kang

Organic Preparations and Procedures International, 2000 , vol. 32, # 2 p. 175 - 183 Title/Abstract Full Text View citing articles Show Details

3

Synthesize Find similar With sodium cyanoborohydride in methanol

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Rx-ID: 1089368 Find similar reactions

Coutts; Jones; Liu

Biomedical Mass Spectrometry, 1978 , vol. 5, # 6 p. 418 - 422 Title/Abstract Full Text View citing articles Show Details


4

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Rx-ID: 4125430 Find similar reactions

Beckett,A.H. et al.

Tetrahedron, 1975 , vol. 31, p. 1531 - 1535 Full Text View citing articles Show Details

(i) PhCHO, MgSO4, (ii) MCPBA, (iii) aq. H2SO4; Multistep reaction;

5

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Rx-ID: 4127074 Find similar reactions

Beckett,A.H. et al.

Tetrahedron, 1975 , vol. 31, p. 1531 - 1535 Full Text View citing articles Show Details

(i) PhCHO, MgSO4, (ii) MCPBA, (iii) aq. H2SO4; Multistep reaction;

6

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Rx-ID: 4136233 Find similar reactions

(i) PhCHO, MgSO4, (ii) MCPBA, (iii) aq. H2SO4; Multistep reaction;

Multi-step reaction with 2 steps 1: 50 percent Spectr. / 2 eq. oxaziridinium tetrafluoroborate derived from N-methyl-1,2,3,4-tetrahydroisoquinoline / CH2Cl2 / 0.25 h / 0 °C 2: NaCNBH3 / methanol / pH=3 View Scheme

Beckett,A.H. et al.

Tetrahedron, 1975 , vol. 31, p. 1531 - 1535 Full Text View citing articles Show Details

Hanquet, Gilles; Lusinchi, Xavier

Tetrahedron, 1994 , vol. 50, # 42 p. 12185 - 12200 Title/Abstract Full Text View citing articles Show Details


7

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Rx-ID: 7363571 Find similar reactions

Gal et al.

Acta Pharmaceutica Suecica, 1977 , vol. 14, p. 335,340 Full Text Show Details

entspr. Oxim-hydrochlorid, NaBH3CN;

1-Phenyl-2-nitropropen, LiAlH4;

Lindeke et al.

Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1976 , vol. 30, p. 789 Full Text Show Details

1-Phenyl-2-propanonoxim, B2H6;

Lindeke et al.

Acta Pharmaceutica Suecica, 1973 , vol. 10, p. 493,500 Full Text Show Details

8

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Rx-ID: 15816724 Find similar reactions

Multi-step reaction with 2 steps 1: NH2OH*HCl,; pyridine / ethanol / Heating 2: NaCNBH3 / tetrahydrofuran; acetic acid / 24 h / 20 °C View Scheme

Katritzky, Alan R.; Cui, Xilin; Long, Qiuhe; Yang, Baozhen; Wilcox, Allan L.; Zhang, Yong-Kang

Organic Preparations and Procedures International, 2000 , vol. 32, # 2 p. 175 - 183 Title/Abstract Full Text View citing articles Show Details

9

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With hydrochlorid acid; palladium on activated charcoal; hydrogen in methanol

Rx-ID: 41007808 Find similar reactions

Sandoval, David; Samoshin, Andrey V.; Read De Alaniz, Javier


T=20°C;

Organic Letters, 2015 , vol. 17, # 18 p. 4514 - 4517 Title/Abstract Full Text View citing articles Show Details

10

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90%

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Rx-ID: 10054650 Find similar reactions

With hydrogenchloride; NaBD3CN in tetrahydrofuran; methanol

T=0 - 20°C; 3 h;

Cashman, John R.; Xiong, Yeng N.; Lifen, Xu; Janowsky, Aaron

Journal of Pharmacology and Experimental Therapeutics, 1999 , vol. 288, # 3 p. 1251 - 1260 Title/Abstract Full Text View citing articles Show Details

11

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Rx-ID: 7303499 Find similar reactions

Gal et al.

Acta Pharmaceutica Suecica, 1977 , vol. 14, p. 335,340 Full Text Show Details

Oxim (IV)-Hydrochlorid, NaBH3CN;

12

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Rx-ID: 7303658 Find similar reactions

Coutts et al.

Canadian Journal of Pharmaceutical Sciences, 1978 , vol. 13, p. 61,62 Chem.Abstr., vol. 90, # 71846z Full Text Show Details

1-Phenyl-2-propanon-d(5), Hydroxylamin;

A

B

C


13

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Product distribution;

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Gilsdorf; Nord

Journal of the American Chemical Society, 1952 , vol. 74, p. 1837,1841 Full Text View citing articles Show Details

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