Reaxys
PubChem
eMolecules
Reactions (368)
Substances (168)
Citations (3449)
Structure
Structure/Compound Data Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; D-mandelate
N° of preparations All Preps | All Reactions
Available Data
no reactions.
Physical Data (1)
1
no reactions.
Physical Data (1)
1
N° of ref.
Reaxys Registry Number: 6121829
CAS Registry Number: 85445-00-7 Type of Substance: isocyclic Molecular Formula: C8H8O3*C10H15N Linear Structure Formula: C10H15N*C8H8O3
Molecular Weight: 301.386
InChI Key: QMSAZBMWZVIYFU-IRAZKAIOSA-N
100
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; D-mandelate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; D-Mandelat Physical Data Melting Point (1) Melting Point
Reference
96 - 97 °C
Chiang; Li
Journal of the Chinese Chemical Society (Peking), 1951 , vol. 18, p. 161 Full Text Show Details
Chemical Name: methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; D-mandelate Reaxys Registry Number: 6121830
CAS Registry Number: 85444-98-0 Type of Substance: isocyclic Molecular Formula: C8H8O3*C10H15N Linear Structure Formula: C10H15N*C8H8O3
Molecular Weight: 301.386
InChI Key: QMSAZBMWZVIYFU-XPNWLKPYSA-N
101
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; D-mandelate, Methyl-((R)-1-methyl-2-phenyl-aethyl)-amin; D-Mandelat Physical Data Melting Point (1) Melting Point
Reference
96 - 97 °C
Chiang; Li
Journal of the Chinese Chemical Society (Peking), 1951 , vol. 18, p. 161 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; 4-chloro benzoate
no reactions.
Physical Data (1)
1
no reactions.
Physical Data (1)
1
Reaxys Registry Number: 6102966
Type of Substance: isocyclic Molecular Formula: C7H5ClO2*C10H15N Linear Structure Formula: C10H15N*C7H5ClO2
Molecular Weight: 305.804
InChI Key: XBLJNBMHELHIBZ-FVGYRXGTSA-N 102
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; 4-chloro benzoate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; 4-Chlor-benzoat Physical Data Melting Point (1) Melting Point
Reference
90 °C
Chiang; Li
Journal of the Chinese Chemical Society (Peking), 1951 , vol. 18, p. 161 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; 2-chloro benzoate Reaxys Registry Number: 6121697
Type of Substance: isocyclic Molecular Formula: C7H5ClO2*C10H15N Linear Structure Formula: C10H15N*C7H5ClO2
Molecular Weight: 305.804
InChI Key: DBOYAFWLKMNWGS-FVGYRXGTSA-N 103
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; 2-chloro benzoate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; 2-Chlor-benzoat Physical Data Melting Point (1) Melting Point
Reference
93 - 95 °C
Chiang; Li
Journal of the Chinese Chemical Society (Peking), 1951 , vol. 18, p. 161 Full Text Show Details
Chemical Name: methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; 2-chloro benzoate
no reactions.
Physical Data (1)
1
Reaxys Registry Number: 6121698
Type of Substance: isocyclic Molecular Formula: C7H5ClO2*C10H15N Linear Structure Formula: C10H15N*C7H5ClO2
Molecular Weight: 305.804
InChI Key: DBOYAFWLKMNWGS-SBSPUUFOSA-N 104
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; 2-chloro benzoate, Methyl-((R)-1-methyl-2-phenyl-aethyl)-amin; 2-Chlor-benzoat Physical Data Melting Point (1) Melting Point
Reference
94 - 96 °C
Chiang; Li
Journal of the Chinese Chemical Society (Peking), 1951 , vol. 18, p. 161 Full Text Show Details
Chemical Name: methamphetamine, nicotine Reaxys Registry Number: 30194874
Molecular Formula: C10H14N2*C10H15N Linear Structure Formula: C10H14N2*C10H15N Molecular Weight: 311.47
InChI Key: LGKOEWOISUIUOT-PPHPATTJSA-N 105
no reactions.
1
Synthesize | Hide Details Find similar Chemical Names and Synonyms methamphetamine, nicotine Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; 4-nitro benzoate
no reactions.
Physical Data (4)
Reaxys Registry Number: 6103955
Type of Substance: isocyclic Molecular Formula: C7H5NO4*C10H15N Linear Structure Formula: C10H15N*C7H5NO4
Molecular Weight: 316.357
InChI Key: IUJVWZVIBWYPPQ-FVGYRXGTSA-N 106
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; 4-nitro benzoate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; 4-Nitro-benzoat Physical Data Melting Point (2) Melting Point
Solvent (Melting Point)
Reference
112 - 113 °C
diethyl ether
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
112 - 113 °C
acetone
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
Optical Rotatory Power (2) Type (Optical Rotatory Power)
Concentration (Optical Rotatory Power)
Solvent (Optical Rotatory Power)
Optical Rotatory Power
Wavelength (Optical Rotatory Power)
Temperature (Optical Rotatory Power)
[alpha]
c=0.8
ethanol
-7.9 deg
589 nm
23 °C
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
[alpha]
c=0.8
H2O
6.3 deg
589 nm
23 °C
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
Reference
1
Chemical Name: meth amphetamine
no reactions.
5
Reaxys Registry Number: 30138015
Molecular Formula: C9H13N*C10H15N*ClH Linear Structure Formula: C9H13N*C10H15N*ClH Molecular Weight: 320.906
InChI Key: NTUUZNGYUKZLOZ-WWPIYYJJSA-N 107
Synthesize | Hide Details Find similar Chemical Names and Synonyms meth amphetamine Chemical Name: dl-methamphetamine diliturate
no reactions.
Physical Data (3)
1
no reactions.
Physical Data (1)
1
Reaxys Registry Number: 6762990
Type of Substance: heterocyclic Molecular Formula: C4H3N3O5*C10H15N Linear Structure Formula: C10H15N*C4H3N3O5
Molecular Weight: 322.321
InChI Key: MNKHGIDBFQAUMO-UHFFFAOYSA-N 108
Synthesize | Hide Details Find similar Chemical Names and Synonyms dl-methamphetamine diliturate Physical Data Crystal Phase (1) Description (Crystal Phase)
Reference
Crystal habit
Julian; Plein
Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 6 p. 704 - 707 Title/Abstract Full Text View citing articles Show Details
Crystal System (1) Crystal System
Reference
monoclinic
Julian; Plein
Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 6 p. 704 - 707 Title/Abstract Full Text View citing articles Show Details
Optics (1) Description (Optics)
Reference
Crystal refractive indices
Julian; Plein
Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 6 p. 704 - 707 Title/Abstract Full Text View citing articles Show Details
Chemical Name: methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; (S)-α-bromo isovalerate
Reaxys Registry Number: 6121109
Type of Substance: isocyclic Molecular Formula: C5H9BrO2*C10H15N Linear Structure Formula: C10H15N*C5H9BrO2
Molecular Weight: 330.265
InChI Key: GWBFJLCROABIFN-VBZMPERESA-N
109
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; (S)-α-bromo isovalerate, Methyl-((R)-1-methyl-2-phenyl-aethyl)-amin; (S)-α-Brom-isovalerat Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
96 - 97 °C
H2O
Senoh
Yakugaku Zasshi, 1951 , vol. 71, p. 798 Chem.Abstr., 1952 , p. 2501 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; (R)-α-bromo isovalerate
no reactions.
Physical Data (1)
1
no reactions.
Bioactivity (3)
3
Reaxys Registry Number: 6121110
Type of Substance: isocyclic Molecular Formula: C5H9BrO2*C10H15N Linear Structure Formula: C10H15N*C5H9BrO2
Molecular Weight: 330.265
InChI Key: GWBFJLCROABIFN-AGAVTAENSA-N
110
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; (R)-α-bromo isovalerate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; (R)-α-Brom-isovalerat Physical Data Melting Point (1) Melting Point
Reference
96 - 97 °C
Senoh
Yakugaku Zasshi, 1951 , vol. 71, p. 798 Chem.Abstr., 1952 , p. 2501 Full Text Show Details
Chemical Name: dextromethamphetamine hydrochloride Reaxys Registry Number: 9418777
Type of Substance: isocyclic Molecular Formula: 2C10H15N*ClH Linear Structure Formula: 2C10H15N*ClH Molecular Weight: 334.933
InChI Key: TWXDDNPPQUTEOV-FVGYRXGTSA-N
111
Synthesize | Hide Details Find similar Chemical Names and Synonyms dextromethamphetamine hydrochloride, METH methamphetamine Bioactivity Pharmacological Data (3) 1 of 3
2 of 3
Comment (Pharmacological Data)
Bioactivities present
Reference
Shappell, Scott A.; Kearns, Gregory L.; Valentine, Jimmie L.; Neri, David F.; DeJohn, Charles A.
Journal of Clinical Pharmacology, 1996 , vol. 36, # 11 p. 1051 - 1063 Title/Abstract Full Text View citing articles Show Details
Klupczynska, Agnieszka; Dereziński, Paweł; Krysztofiak, Janusz; Kokot, Zenon J.
Forensic Science International, 2016 , vol. 260, p. 14 - 21 Title/Abstract Full Text View citing articles Show Details
Jafari Giv, Mahsa
Cardiovascular Toxicology, 2017 , vol. 17, # 1 p. 13 - 24 Title/Abstract Full Text Show Details
Effect (Pharmacological Data)
pharmacokinetics
Species or TestSystem (Pharmacological Data)
human
Sex
male
Route of Application
peroral
Concentration (Pharmacological Data)
30 mg/70kg
Kind of Dosing (Pharmacological Data)
title comp. administered at 8:40 AM (day session) or 8:40 PM (night session)
Method (Pharmacological Data)
10 healthy subjects; methamphetamine levels of serum and urine determined by GC/MS method; Cmax, Tmax, Ka, Ke, AUC, Clt, Clr, Vd
Further Details (Pharmacological Data)
Cmax is the peak conc of methamphetamine, Tmax its time; Ka and Ke are absorption and elimination rate constants; Clt and Clr are total and renal clearance; Vd=steady-state volume of distribution
Half-life Time (Pharmacological Data)
9.11 - 10.81 h
Results
serum conc.-time diagram given; kinetic data for day and night sessions in tables and diagrams; no differences in day-vs.-night kinetic profile
Metabolite (Pharmacological Data)
dexamfetamine [Reaxys RN: 2205872]
Reference
Shappell, Scott A.; Kearns, Gregory L.; Valentine, Jimmie L.; Neri, David F.; DeJohn, Charles A.
Journal of Clinical Pharmacology, 1996 , vol. 36, # 11 p. 1051 - 1063 Title/Abstract Full Text View citing articles Show Details
3 of 3
Effect (Pharmacological Data)
behavioural symptoms
Species or TestSystem (Pharmacological Data)
human
Sex
male
Route of Application
peroral
Concentration (Pharmacological Data)
30 mg/70kg
Kind of Dosing (Pharmacological Data)
title comp. administered at 8:40 AM (day session) or 8:40 PM (night session)
Method (Pharmacological Data)
10 healthy subjects; recognitive performance (auditory divided attention, spatial memory, psychomotor tasks) subjective fatigue scale determined during 6:30 AM - 9:00 PM (day session) and 6:30 PM - 9:00 AM (night session); blood pressures measured
Results
no correlation between behavioral parameters and serum methamphetamine levels; diastolic and systolic blood pressures vs. time diagrams showed maxima
Reference
Shappell, Scott A.; Kearns, Gregory L.; Valentine, Jimmie L.; Neri, David F.; DeJohn, Charles A.
Journal of Clinical Pharmacology, 1996 , vol. 36, # 11 p. 1051 - 1063 Title/Abstract Full Text View citing articles Show Details
Chemical Name: D,L-Methylamphetamin-p-chlorphenoxyacetat Reaxys Registry Number: 4076518
CAS Registry Number: 98739-95-8 Type of Substance: isocyclic Molecular Formula: C8H7ClO3*C10H15N Linear Structure Formula: C10H15N*C8H7ClO3
Molecular Weight: 335.831
InChI Key: GEPDUXWJAAGKEP-UHFFFAOYSA-N
112
1 prep out of 1 reactions.
Physical Data (1)
1
no reactions.
Identification Physical Data (1) Spectra (4)
1
Synthesize | Hide Details Find similar Chemical Names and Synonyms D,L-Methylamphetamin-p-chlorphenoxyacetat Physical Data Melting Point (1) Melting Point
Reference
81 °C
Laboratoire d'Analyses et de Recherches Biologiques Mauvernay; C.E.R.M.
Patent: BE639286 , 1962 ; Chem.Abstr., 1965 , vol. 62, # 11738b Full Text Show Details
Reaxys Registry Number: 10612519
Type of Substance: heterocyclic Molecular Formula: C9H12N2O4*C10H15N Linear Structure Formula: C10H15N*C9H12N2O4
Molecular Weight: 361.441
InChI Key: DWYKRVKDMLFZGE-FVGYRXGTSA-N
113
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Identification Substance Label (1) Label
Reference
4 <H&-1%L>2<R1NMeH2>2
Reviriego, Felipe; Rodriguez-Franco, Maria Isabel; Navarro, Pilar; Garcia-Espana, Enrique; Liu-Gonzalez, Malva; Verdejo, Begona; Domenech, Antonio
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16458 - 16459 Title/Abstract Full Text View citing articles Show Details
Physical Data Melting Point (1) Melting Point
Reference
83 - 85 °C
Reviriego, Felipe; Rodriguez-Franco, Maria Isabel; Navarro, Pilar; Garcia-Espana, Enrique; Liu-Gonzalez, Malva; Verdejo, Begona; Domenech, Antonio
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16458 - 16459 Title/Abstract Full Text View citing articles Show Details
Spectra NMR Spectroscopy (2) Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Frequency (NMR Spectroscopy)
Chemical shifts
1H
dimethylsulfoxided6
500 MHz
Reviriego, Felipe; Rodriguez-Franco, Maria Isabel; Navarro, Pilar; Garcia-Espana, Enrique; Liu-Gonzalez, Malva; Verdejo, Begona; Domenech, Antonio
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16458 - 16459 Title/Abstract Full Text View citing articles Show Details
Chemical shifts
13C
dimethylsulfoxided6
125 MHz
Reviriego, Felipe; Rodriguez-Franco, Maria Isabel; Navarro, Pilar; Garcia-Espana, Enrique; Liu-Gonzalez, Malva; Verdejo, Begona; Domenech, Antonio
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16458 - 16459 Title/Abstract Full Text View citing articles Show Details
Reference
IR Spectroscopy (1) Description (IR Spectroscopy)
Solvent (IR Spectroscopy)
Bands
KBr
Reference Reviriego, Felipe; Rodriguez-Franco, Maria Isabel; Navarro, Pilar; Garcia-Espana, Enrique; Liu-Gonzalez, Malva; Verdejo, Begona; Domenech, Antonio
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16458 - 16459 Title/Abstract Full Text View citing articles Show Details
Mass Spectrometry (1) Description (Mass Spectrometry) fast atom bombardment (FAB) spectrum
Reference Reviriego, Felipe; Rodriguez-Franco, Maria Isabel; Navarro, Pilar; Garcia-Espana, Enrique; Liu-Gonzalez, Malva; Verdejo, Begona; Domenech, Antonio
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16458 - 16459 Title/Abstract Full Text View citing articles Show Details
Chemical Name: (+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine; picrate
114
Reaxys Registry Number: 6113532
CAS Registry Number: 13857-60-8, 59920-95-5 Type of Substance: isocyclic Molecular Formula: C6H3N3O7*C10H15N Linear Structure Formula: C10H15N*C6H3N3O7
Molecular Weight: 378.342
InChI Key: OPLMVANOTUKEPS-UHFFFAOYSA-N
no reactions.
Physical Data (4)
3
Synthesize | Hide Details Find similar Chemical Names and Synonyms (+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine; picrate, (+-)-Methyl-(1-methyl-2-phenyl-aethyl)-amin; Picrat Physical Data Melting Point (3) Melting Point
Solvent (Melting Point)
Reference
122 °C
methanol
Abe
Yakugaku Zasshi, 1955 , vol. 75, p. 159,162 Chem.Abstr., 1956 , p. 1779 Full Text Show Details
126 °C
H2O
Evdokimoff
Gazzetta Chimica Italiana, 1947 , vol. 77, p. 318,323,325 Full Text Show Details
128 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
gelb
Abe
Yakugaku Zasshi, 1955 , vol. 75, p. 159,162 Chem.Abstr., 1956 , p. 1779 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; picrate Reaxys Registry Number: 6113533
CAS Registry Number: 13857-60-8, 59920-95-5 Type of Substance: isocyclic Molecular Formula: C6H3N3O7*C10H15N Linear Structure Formula: C10H15N*C6H3N3O7
Molecular Weight: 378.342
InChI Key: OPLMVANOTUKEPS-FVGYRXGTSA-N
115
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; picrate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; Picrat, D-desoxyephedrine picrate Physical Data
1 prep out of 1 reactions.
Physical Data (2) Spectra (1)
3
Melting Point (2) Melting Point
Reference
145.7 - 147.1 °C
Chatten; Levi
Analytical Chemistry, 1959 , vol. 31, p. 1581,1582,1585 Full Text View citing articles Show Details
144 - 145 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Spectra IR Spectroscopy (1) Description (IR Spectroscopy)
Solvent (IR Spectroscopy)
Comment (IR Spectroscopy)
Reference
Spectrum
KBr
4000 - 650 cm**(-1)
Chatten; Levi
Analytical Chemistry, 1959 , vol. 31, p. 1581,1582,1585 Full Text View citing articles Show Details
Chemical Name: methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; picrate
no reactions.
Physical Data (1)
1
no reactions.
Physical Data (1)
1
Reaxys Registry Number: 6113534
CAS Registry Number: 59920-95-5 Type of Substance: isocyclic Molecular Formula: C6H3N3O7*C10H15N Linear Structure Formula: C10H15N*C6H3N3O7
Molecular Weight: 378.342
InChI Key: OPLMVANOTUKEPS-SBSPUUFOSA-N
116
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; picrate, Methyl-((R)-1-methyl-2-phenyl-aethyl)-amin; Picrat Physical Data Melting Point (1) Melting Point
Reference
144 - 145 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amin; (1S)-2-oxo-bornane10-sulfonate Reaxys Registry Number: 6113089
Type of Substance: isocyclic Molecular Formula: C10H15N*C10H16O4S Linear Structure Formula: C10H16O4S*C10H15N Molecular Weight: 381.536
InChI Key: SLORXCQEJDMGNH-LIGZPJPGSA-N
117
Synthesize | Hide Details
Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amin; (1S)-2-oxo-bornane-10-sulfonate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; (1S)-2-Oxo-bornan-10sulfonat Physical Data Melting Point (1) Melting Point
Reference
124 - 125 °C
Chiang; Li
Journal of the Chinese Chemical Society (Peking), 1951 , vol. 18, p. 161 Full Text Show Details
Chemical Name: methyl-((R)-1-methyl-2-phenyl-ethyl)-amin; (1S)-2-oxo-bornane10-sulfonate
no reactions.
Physical Data (1)
1
no reactions.
1
no reactions.
Physical Data (8)
1
Reaxys Registry Number: 6113090
Type of Substance: isocyclic Molecular Formula: C10H15N*C10H16O4S Linear Structure Formula: C10H16O4S*C10H15N Molecular Weight: 381.536
InChI Key: SLORXCQEJDMGNH-GUIHCAGKSA-N
118
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((R)-1-methyl-2-phenyl-ethyl)-amin; (1S)-2-oxo-bornane-10-sulfonate, Methyl-((R)-1-methyl-2-phenyl-aethyl)-amin; (1S)-2-Oxo-bornan-10sulfonat Physical Data Melting Point (1) Melting Point
Reference
124 - 125 °C
Chiang; Li
Journal of the Chinese Chemical Society (Peking), 1951 , vol. 18, p. 161 Full Text Show Details
Chemical Name: tional ice Reaxys Registry Number: 30246026
Molecular Formula: C8H18O4S2*C10H15N Linear Structure Formula: C8H18O4S2*C10H15N Molecular Weight: 391.596
InChI Key: KQLZLQDGXVVCNC-FVGYRXGTSA-N
119
Synthesize | Hide Details Find similar Chemical Names and Synonyms tional ice Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; sulfate
Reaxys Registry Number: 6100466
CAS Registry Number: 17086-30-5, 20189-61-1, 28297-73-6, 28297-74-7, 58670-90-9 Type of Substance: isocyclic Molecular Formula: 2C10H15N*H2O4S Linear Structure Formula: 2C10H15N*H2O4S Molecular Weight: 396.551
InChI Key: SOBAVQRLBCJNQT-FVGYRXGTSA-N
120
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; sulfate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; Sulfat Physical Data Melting Point (2) Melting Point
Solvent (Melting Point)
Reference
124 - 125 °C
ethanol
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
124 - 125 °C
acetone
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
Optical Rotatory Power (6) Type (Optical Rotatory Power)
Concentration (Optical Rotatory Power)
Solvent (Optical Rotatory Power)
Optical Rotatory Power
Wavelength (Optical Rotatory Power)
Temperature (Optical Rotatory Power)
[alpha]
c=2
ethanol
-10.6 deg
589 nm
20 °C
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
[alpha]
c=4
ethanol
-10.3 deg
589 nm
29 °C
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
[alpha]
c=2
methanol
-7.8 deg
589 nm
24 °C
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
[alpha]
c=2
H2O
12.6 deg
589 nm
20 °C
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
[alpha]
c=4
H2O
12.5 deg
589 nm
29 °C
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
[alpha]
c=0.2
CHCl3
-13.9 deg
589 nm
16 °C
Chiang
Journal of the Chinese Chemical Society (Peking), 1950 , vol. 17, p. 106,112 Full Text Show Details
Chemical Name: sulfanilic acid pyrimidin-2-ylamide; methyl-(1-methyl-2-phenylethyl)-amine salt
Reference
no reactions.
Physical Data (4)
1
Reaxys Registry Number: 3847059
Type of Substance: heterocyclic Molecular Formula: C10H10N4O2S*C10H15N Linear Structure Formula: C10H15N*C10H10N4O2S Molecular Weight: 399.517
InChI Key: QBVXTXBYXXJVCN-UHFFFAOYSA-N
121
Synthesize | Hide Details Find similar Chemical Names and Synonyms sulfanilic acid pyrimidin-2-ylamide; methyl-(1-methyl-2-phenyl-ethyl)-amine salt, Sulfanilsaeure-pyrimidin-2-ylamid; Methyl-(1-methyl-2-phenylaethyl)-amin-Salz Physical Data Melting Point (1) Melting Point
Reference
187 - 189 °C
Hamilton et al.
Journal of the American Pharmaceutical Association (1912-1977), 1944 , vol. 33, p. 142,143 Full Text Show Details
Crystal System (1) Crystal System
Reference
monoclinic
Hamilton et al.
Journal of the American Pharmaceutical Association (1912-1977), 1944 , vol. 33, p. 142,143 Full Text Show Details
Solubility (MCS) (2) Solubility
Saturation
Temperature (Solubility (MCS))
Solvent (Solubility (MCS))
Reference
12.5 g·l-1
in solution
2 °C
H2O
Hamilton et al.
Journal of the American Pharmaceutical Association (1912-1977), 1944 , vol. 33, p. 142,143 Full Text Show Details
15.2 g·l-1
in solution
30 °C
H2O
Hamilton et al.
Journal of the American Pharmaceutical Association (1912-1977), 1944 , vol. 33, p. 142,143 Full Text Show Details
Chemical Name: sulfanilic acid thiazol-2-ylamide; (+-)-methyl-(1-methyl-2-phenylethyl)-amine salt Reaxys Registry Number: 3843875
Type of Substance: heterocyclic Molecular Formula: C9H9N3O2S2*C10H15N Linear Structure Formula: C10H15N*C9H9N3O2S2
Molecular Weight: 404.557
InChI Key: IWDYBSBBBKFGMW-UHFFFAOYSA-N
122
Synthesize | Hide Details Find similar Chemical Names and Synonyms sulfanilic acid thiazol-2-ylamide; (+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine salt, Sulfanilsaeure-thiazol-2-ylamid; (+-)-Methyl-(1-methyl-2-phenyl-
no reactions.
Physical Data (4)
1
aethyl)-amin-Salz Physical Data Melting Point (1) Melting Point
Reference
118 - 120 °C
Hamilton et al.
Journal of the American Pharmaceutical Association (1912-1977), 1944 , vol. 33, p. 142,143 Full Text Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
monoklin
Hamilton et al.
Journal of the American Pharmaceutical Association (1912-1977), 1944 , vol. 33, p. 142,143 Full Text Show Details
Solubility (MCS) (2) Solubility
Saturation
Temperature (Solubility (MCS))
Solvent (Solubility (MCS))
Reference
11.9 g·l-1
in solution
2 °C
H2O
Hamilton et al.
Journal of the American Pharmaceutical Association (1912-1977), 1944 , vol. 33, p. 142,143 Full Text Show Details
16.7 g·l-1
in solution
30 °C
H2O
Hamilton et al.
Journal of the American Pharmaceutical Association (1912-1977), 1944 , vol. 33, p. 142,143 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; picrolonate Reaxys Registry Number: 6113714
Type of Substance: heterocyclic Molecular Formula: C10H8N4O5*C10H15N Linear Structure Formula: C10H15N*C10H8N4O5
Molecular Weight: 413.433
InChI Key: CTZVWXXMDVEGAI-NPULLEENSA-N
123
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; picrolonate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; Picrolonat Physical Data Melting Point (1) Melting Point
Reference
183 °C
Dultz
Zeitschrift fuer Analytische Chemie, 1940 , vol. 120, p. 84,86 Full Text Show Details
Kofler,L. u. A.
Thermo-Mikro-Methoden, 3. Aufl.<Weinheim 1954>> S. 532 Full Text Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
gelb
Dultz
Zeitschrift fuer Analytische Chemie, 1940 , vol. 120, p. 84,86 Full Text Show Details
no reactions.
Physical Data (2)
2
Kofler,L. u. A.
Thermo-Mikro-Methoden, 3. Aufl.<Weinheim 1954>> S. 532 Full Text Show Details
Chemical Name: DMI ice
no reactions.
2
no reactions.
Physical Data (1)
1
no reactions.
Identification Physical Data (1)
1
Reaxys Registry Number: 30235585
Molecular Formula: C10H15N*C18H22N2
Linear Structure Formula: C10H15N*C18H22N2
Molecular Weight: 415.622
InChI Key: JYLSUZICRFUDJS-NPULLEENSA-N
124
Synthesize | Hide Details Find similar Chemical Names and Synonyms DMI ice Chemical Name: 4,6,2'-trimethyl-3-methylen-4'-oxo-3H-spiro[benzofuran-2,1'cyclopent-2'-ene]-3'-carboxylic acid ; (+-)-2-methylamino-1phenyl-propane salt Reaxys Registry Number: 3854778
Type of Substance: heterocyclic Molecular Formula: C10H15N*C17H16O4
Linear Structure Formula: C17H16O4*C10H15N Molecular Weight: 433.547
InChI Key: XCZRBBXYDXMESM-UHFFFAOYSA-N
125
Synthesize | Hide Details Find similar Chemical Names and Synonyms 4,6,2'-trimethyl-3-methylen-4'-oxo-3H-spiro[benzofuran-2,1'-cyclopent-2'-ene]-3'-carboxylic acid ; (+-)-2-methylamino-1-phenyl-propane salt, 4,6,2'Trimethyl-3-methylen-4'-oxo-3H-spiro[benzofuran-2,1'-cyclopent-2'-en]-3'-carbonsaeure; (+-)-2-Methylamino-1-phenyl-propan-Salz Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
150 °C
benzene diethyl ether
Dean et al.
Journal of the Chemical Society, 1953 , p. 1250,1253 Journal of the Chemical Society, 1957 , p. 1577 Full Text Show Details
Chemical Name: (+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine; trichloromercurate(II) Reaxys Registry Number: 6112741
Type of Substance: isocyclic Molecular Formula: C10H15N*Cl3Hg*H Linear Structure Formula: C10H15N*Cl3Hg(1-)*H(1+)
126
Molecular Weight: 457.193
InChI Key: KISDFACEDNITLX-UHFFFAOYSA-L
Synthesize | Hide Details Find similar Chemical Names and Synonyms (+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine; trichloromercurate(II), (+-)-Methyl-(1-methyl-2-phenyl-aethyl)-amin; Trichloromercurat(II) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Hg{X}3
X
3
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Hg{X}3
X
3
Multi-Center Ligands (1)
Physical Data Melting Point (1) Melting Point
Reference
128 - 130 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; trichloromercurate(II)
no reactions.
Reaxys Registry Number: 6112742
Type of Substance: isocyclic Molecular Formula: C10H15N*Cl3Hg*H Linear Structure Formula: C10H15N*Cl3Hg(1-)*H(1+)
Molecular Weight: 457.193
InChI Key: KISDFACEDNITLX-ZWACTXNCSA-L
127
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; trichloromercurate(II), Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; Trichloromercurat(II) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Hg{X}3
X
3
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Hg{X}3
X
3
Multi-Center Ligands (1)
Physical Data
Identification Physical Data (1)
1
Melting Point (1) Melting Point
Reference
214 - 215 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Chemical Name: methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; trichloromercurate(II)
no reactions.
Reaxys Registry Number: 6112743
Type of Substance: isocyclic Molecular Formula: C10H15N*Cl3Hg*H Linear Structure Formula: C10H15N*Cl3Hg(1-)*H(1+)
Identification Physical Data (1)
1
Physical Data (1) Spectra (1)
1
Molecular Weight: 457.193
InChI Key: KISDFACEDNITLX-RASHCQHBSA-L
128
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; trichloromercurate(II), Methyl-((R)-1-methyl-2-phenyl-aethyl)-amin; Trichloromercurat(II) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Hg{X}3
X
3
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Hg{X}3
X
3
Multi-Center Ligands (1)
Physical Data Melting Point (1) Melting Point
Reference
152 - 153 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; reineckate Reaxys Registry Number: 6111361
Type of Substance: isocyclic Molecular Formula: 4CNS*C10H15N*Cr*H*2H3N Linear Structure Formula: C10H15N*4CNS(1-
)*Cr(3+)*2H
129
N*H(1+)
3
Molecular Weight: 468.636
InChI Key: LJWJTASGTMGBRI-DXYFNVQQSA-N
Synthesize | Hide Details
no reactions.
Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; reineckate, Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; Reineckat Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
120.8 - 123.9 °C
aq. ethanol
Chatten; Levi
Analytical Chemistry, 1959 , vol. 31, p. 1581,1582,1585 Full Text View citing articles Show Details
Spectra IR Spectroscopy (1) Description (IR Spectroscopy)
Solvent (IR Spectroscopy)
Comment (IR Spectroscopy)
Reference
Spectrum
KBr
4000 - 650 cm**(-1)
Chatten; Levi
Analytical Chemistry, 1959 , vol. 31, p. 1581,1582,1585 Full Text View citing articles Show Details
Chemical Name: Methamphetamin-tetraphenylborat Reaxys Registry Number: 6311962
Type of Substance: isocyclic Molecular Formula: C10H15N*C24H20B*H Linear Structure Formula: C24H20B(1-)*C10H15N*H(1+)
Molecular Weight: 469.478
InChI Key: UVQXUSSMGDNJDH-NPULLEENSA-O
130
Synthesize | Hide Details Find similar Chemical Names and Synonyms Methamphetamin-tetraphenylborat Physical Data Melting Point (1) Melting Point
Reference
127 - 128 °C
SINSHEIMER; SMITH
Journal of pharmaceutical sciences, 1963 , vol. 52, p. 1080 - 1085 Title/Abstract Full Text View citing articles Show Details
Spectra IR Spectroscopy (1) Description (IR Spectroscopy)
Reference
Spectrum
SINSHEIMER; SMITH
Journal of pharmaceutical sciences, 1963 , vol. 52, p. 1080 - 1085 Title/Abstract Full Text View citing articles Show Details
UV/VIS Spectroscopy (2) Description (UV/VIS Spectroscopy)
Reference
Spectrum
SINSHEIMER; SMITH
no reactions.
Physical Data (1) Spectra (3)
1
Journal of pharmaceutical sciences, 1963 , vol. 52, p. 1080 - 1085 Title/Abstract Full Text View citing articles Show Details
Absorption maxima
SINSHEIMER; SMITH
Journal of pharmaceutical sciences, 1963 , vol. 52, p. 1080 - 1085 Title/Abstract Full Text View citing articles Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; tetrachloroaurate (III)
no reactions.
Reaxys Registry Number: 6112739
Type of Substance: isocyclic Molecular Formula: AuCl4*C10H15N*H Linear Structure Formula: C10H15N*AuCl4(1-)*H(1+)
Molecular Weight: 489.022
InChI Key: STXJZSIETYQJNY-SADGAIANSA-K
131
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; tetrachloroaurate (III), Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; Tetrachloroaurat(III) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Au{X}4
X
4
Multi-Center Ligands (1) Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Au{X}4
X
4
Physical Data Melting Point (2) Melting Point
Solvent (Melting Point)
Reference
127 - 128 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
126 °C
aq. HCl
Schmidt
Archiv der Pharmazie (Weinheim, Germany), 1914 , vol. 252, p. 121 Archiv der Pharmazie (Weinheim, Germany), 1915 , vol. 253, p. 52 Full Text Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
rotgelbe Nadeln
Schmidt
Archiv der Pharmazie (Weinheim, Germany), 1914 , vol. 252, p. 121 Archiv der Pharmazie (Weinheim, Germany), 1915 , vol. 253, p. 52 Full Text Show Details
Optics (1) Description (Optics)
Reference
Identification Physical Data (4)
3
Keenan
Journal of the American Pharmaceutical Association (1912-1977), 1949 , vol. 38, p. 314 Chem.Abstr., 1949 , p. 8611 Full Text Show Details
Crystal refractive indices
Chemical Name: methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; tetrachloroaurate (III)
no reactions.
Reaxys Registry Number: 6112740
Type of Substance: isocyclic Molecular Formula: AuCl4*C10H15N*H Linear Structure Formula: C10H15N*AuCl4(1-)*H(1+)
Identification Physical Data (1)
1
Identification Physical Data (4)
3
Molecular Weight: 489.022
InChI Key: STXJZSIETYQJNY-NMPKWJFPSA-K
132
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; tetrachloroaurate (III), Methyl-((R)-1-methyl-2-phenyl-aethyl)-amin; Tetrachloroaurat(III) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Au{X}4
X
4
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Au{X}4
X
4
Multi-Center Ligands (1)
Physical Data Melting Point (1) Melting Point
Reference
127 - 128 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Chemical Name: (+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine; tetrachloroaurate (III) Reaxys Registry Number: 6112963
Type of Substance: isocyclic Molecular Formula: AuCl4*C10H15N*H Linear Structure Formula: C10H15N*AuCl4(1-)*H(1+)
Molecular Weight: 489.022
InChI Key: STXJZSIETYQJNY-UHFFFAOYSA-K
133
Synthesize | Hide Details Find similar Chemical Names and Synonyms
no reactions.
(+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine; tetrachloroaurate (III), (+-)-Methyl-(1-methyl-2-phenyl-aethyl)-amin; Tetrachloroaurat(III) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Au{X}4
X
4
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Au{X}4
X
4
Multi-Center Ligands (1)
Physical Data Melting Point (2) Melting Point
Reference
103 - 104 °C
Jacobsen et al.
Skand.Arch.Physiol., 1938 , vol. 79, p. 258,278 Full Text Show Details
108 - 109 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
Nadeln
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Optics (1) Description (Optics)
Reference
Crystal refractive indices
Keenan
Journal of the American Pharmaceutical Association (1912-1977), 1949 , vol. 38, p. 314 Chem.Abstr., 1949 , p. 8611 Full Text Show Details
Chemical Name: ((+)-methamphetamine(+1H))AuCl4
Reaxys Registry Number: 23678276
Molecular Formula: AuCl4*C10H15N*H Linear Structure Formula: AuCl4(1-)*H(1+)*C10H15N Molecular Weight: 489.022
InChI Key: QUDKYMBGLIGJEQ-SADGAIANSA-K
134
Synthesize | Hide Details Find similar Chemical Names and Synonyms ((+)-methamphetamine(+1H))AuCl4, D-methyl(1-phenylpropan-2-yl)azanium tetrachloridoaurate(III) Identification
1 prep out of 1 reactions.
Identification Physical Data (6)
1
One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Au{X}4
X
4
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Au{X}4
X
4
Multi-Center Ligands (1)
Substance Label (1) Label
Reference
2
Wood, Matthew R.; Lalancette, Roger A.
Acta Crystallographica Section C: Crystal Structure Communications, 2013 , vol. 69, # 4 p. 388 - 393 Title/Abstract Full Text View citing articles Show Details
Physical Data Density (1)
Measurement Temperature
Type (Density)
Reference
-173.16 °C
crystallographic
Wood, Matthew R.; Lalancette, Roger A.
Acta Crystallographica Section C: Crystal Structure Communications, 2013 , vol. 69, # 4 p. 388 - 393 Title/Abstract Full Text View citing articles Show Details
Conformation (1) Object of Investigation
Reference
Conformation
Wood, Matthew R.; Lalancette, Roger A.
Acta Crystallographica Section C: Crystal Structure Communications, 2013 , vol. 69, # 4 p. 388 - 393 Title/Abstract Full Text View citing articles Show Details
Crystal Phase (1) Description (Crystal Phase)
Reference
Structure of the solid
Wood, Matthew R.; Lalancette, Roger A.
Acta Crystallographica Section C: Crystal Structure Communications, 2013 , vol. 69, # 4 p. 388 - 393 Title/Abstract Full Text View citing articles Show Details
Crystal System (1) Crystal System
Reference
Monoclinic
Wood, Matthew R.; Lalancette, Roger A.
Acta Crystallographica Section C: Crystal Structure Communications, 2013 , vol. 69, # 4 p. 388 - 393 Title/Abstract Full Text View citing articles Show Details
Interatomic Distances and Angles (1) Description
Comment (Interatomic Distances and Angles)
Reference
Interatomic distances and angles
Single Crystal X-ray Diffraction
Wood, Matthew R.; Lalancette, Roger A.
Acta Crystallographica Section C: Crystal Structure Communications, 2013 , vol. 69, # 4 p. 388 - 393 Title/Abstract Full Text View citing articles Show Details
Space Group (1) Space Group 4
Comment (Space Group)
Reference
a = 7.3561 Å; b = 14.2394 Å; c = 13.9103 Å; β = 90.077 °; Z = 4; T = 100 K; Method = Single crystal X-ray diffraction
Wood, Matthew R.; Lalancette, Roger A.
Acta Crystallographica Section C: Crystal Structure Communications, 2013 , vol. 69, # 4 p. 388 - 393 Title/Abstract Full Text View citing articles Show Details
Chemical Name: sugar Ice
no reactions.
1
no reactions.
1
no reactions.
1
no reactions.
Identification Physical Data (1)
1
Reaxys Registry Number: 30263903
Molecular Formula: C10H15N*C12H22O11
Linear Structure Formula: C10H15N*C12H22O11
Molecular Weight: 491.536
InChI Key: KBUPNXGUGPYWDR-OYHRRBSVSA-N
135
Synthesize | Hide Details Find similar Chemical Names and Synonyms sugar Ice Chemical Name: Lactulose Meth Reaxys Registry Number: 30653560
Molecular Formula: C10H15N*C12H22O11*ClH Linear Structure Formula: C10H15N*C12H22O11*ClH Molecular Weight: 527.997
InChI Key: DONMZGSUCKNXPY-TVCRJLEPSA-N
136
Synthesize | Hide Details Find similar Chemical Names and Synonyms Lactulose Meth Chemical Name: naled ice Reaxys Registry Number: 30656156
Molecular Formula: C4H7Br2Cl2O4P*C10H15N Linear Structure Formula: C4H7Br2Cl2O4P*C10H15N Molecular Weight: 530.021
InChI Key: NUHJIWCEEFLQKM-FVGYRXGTSA-N
137
Synthesize | Hide Details Find similar Chemical Names and Synonyms naled ice Chemical Name: methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; hexachloroplatinate (IV) Reaxys Registry Number: 6106611
Type of Substance: isocyclic Molecular Formula: C10H15N*Cl6Pt*2H
Linear Structure Formula: C10H15N*Cl6Pt(2-)*2H(1+)
Molecular Weight: 559.05
InChI Key: XWILRAAJAXLUOY-AGGFLZQHSA-I
138
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((R)-1-methyl-2-phenyl-ethyl)-amine; hexachloroplatinate (IV), Methyl-((R)-1-methyl-2-phenyl-aethyl)-amin; Hexachloroplatinat(IV) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Pt{X}6
X
6
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Pt{X}6
X
6
Multi-Center Ligands (1)
Physical Data Melting Point (1) Melting Point
Reference
214 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Chemical Name: ICE CER
no reactions.
1
no reactions.
1
Reaxys Registry Number: 30656299
Molecular Formula: C10H15N*C19H17N3O4S2
Linear Structure Formula: C10H15N*C19H17N3O4S2
Molecular Weight: 564.729
InChI Key: WYMQJCVUNPAODO-RWPRVABESA-N
139
Synthesize | Hide Details Find similar Chemical Names and Synonyms ICE CER Chemical Name: Methamphetamine Cocaine Amyl nitrite Reaxys Registry Number: 30638355
Molecular Formula: C5H11NO2*C10H15N*C17H21NO4
Linear Structure Formula: C5H11NO2*C10H15N*C17H21NO4
Molecular Weight: 569.742
InChI Key: HPHYMVOZGOQJEB-NVDOTFARSA-N
140
Synthesize | Hide Details Find similar Chemical Names and Synonyms Methamphetamine Cocaine Amyl nitrite Chemical Name: acrylamide, stearyl meth acrylate
no reactions.
1
no reactions.
Identification Physical Data (4)
3
Reaxys Registry Number: 30265098
Molecular Formula: C3H5NO*C10H15N*C21H40O2*ClH Linear Structure Formula: C3H5NO*C10H15N*C21H40O2*ClH Molecular Weight: 581.323
InChI Key: FAXCOLXZPYKTSG-DBQHITQZSA-N
141
Synthesize | Hide Details Find similar Chemical Names and Synonyms acrylamide, stearyl meth acrylate Chemical Name: (+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine; hexachloroplatinate (IV) Reaxys Registry Number: 6113295
Type of Substance: isocyclic Molecular Formula: 2C10H15N*Cl6Pt*2H Linear Structure Formula: 2C10H15N*Cl6Pt(2-)*2H(1+)
Molecular Weight: 708.285
InChI Key: XWILRAAJAXLUOY-UHFFFAOYSA-I
142
Synthesize | Hide Details Find similar Chemical Names and Synonyms (+-)-methyl-(1-methyl-2-phenyl-ethyl)-amine; hexachloroplatinate (IV), (+-)-Methyl-(1-methyl-2-phenyl-aethyl)-amin; Hexachloroplatinat(IV) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Pt{X}6
X
6
Multi-Center Ligands (1) Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Pt{X}6
X
6
Physical Data Melting Point (3) Melting Point
Reference
198 °C
Asklepia A.G.
Patent: CH233303 , 1942 ; Full Text Show Details
198 - 199 °C
Erlenmeyer; Simon
Helvetica Chimica Acta, 1942 , vol. 25, p. 528 Full Text Show Details
205 °C
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
orangegelbe Prismen
Ogata
Yakugaku Zasshi, 1919 , # 451 p. 751 Chem.Abstr., 1920 , vol. 14, p. 745 Full Text Show Details
Chemical Name: methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; hexachloroplatinate (IV)
no reactions.
Reaxys Registry Number: 6113296
Type of Substance: isocyclic Molecular Formula: 2C10H15N*Cl6Pt*2H Linear Structure Formula: 2C10H15N*Cl6Pt(2-)*2H(1+)
Molecular Weight: 708.285
InChI Key: XWILRAAJAXLUOY-UDXRYNAFSA-I
143
Synthesize | Hide Details Find similar Chemical Names and Synonyms methyl-((S)-1-methyl-2-phenyl-ethyl)-amine; hexachloroplatinate (IV), Methyl-((S)-1-methyl-2-phenyl-aethyl)-amin; Hexachloroplatinat(IV) Identification One-Center Ligands (1) Base Formula (One-Center Ligands)
Formula (One-Center Ligands)
Count (One-Center Ligands)
Pt{X}6
X
6
Base Formula (Multi-Center Ligands)
Formula (Multi-Center Ligands)
Count (Multi-Center Ligands)
Pt{X}6
X
6
Multi-Center Ligands (1)
Identification Physical Data (2)
1
Physical Data Melting Point (1) Melting Point
Solvent (Melting Point)
Reference
208 - 209 °C
aq. HCl
Schmidt
Archiv der Pharmazie (Weinheim, Germany), 1914 , vol. 252, p. 121 Archiv der Pharmazie (Weinheim, Germany), 1915 , vol. 253, p. 52 Full Text Show Details
Crystal Property Description (1) Colour & Other Properties
Reference
rotgelbe Nadeln
Schmidt
Archiv der Pharmazie (Weinheim, Germany), 1914 , vol. 252, p. 121 Archiv der Pharmazie (Weinheim, Germany), 1915 , vol. 253, p. 52 Full Text Show Details
Chemical Name: HEM ice
no reactions.
1
no reactions.
Identification Spectra (1)
1
Reaxys Registry Number: 30828678
Molecular Formula: C10H15N*C34H32N4O4*Fe Linear Structure Formula: C10H15N*C34H32N4O4(2-)*Fe(2+)
Molecular Weight: 765.735
InChI Key: AFVDBWSUKVVQQO-MABAWFGTSA-L
144
Synthesize | Hide Details Find similar Chemical Names and Synonyms HEM ice Reaxys Registry Number: 27418543
Molecular Formula: C10H15N*C68H68O8P4S4*ClH Linear Structure Formula: C68H68O8P4S4*C10H15N*ClH Molecular Weight: 1451.14
InChI Key: KQYNVQPLZSXHKI-UHFFFAOYSA-N
145
Synthesize | Hide Details Find similar
Identification Substance Label (1) Label
Reference
TSiiii+Methamphetamine
Biavardi, Elisa; Menozzi, Daniela; Massera, Chiara; Dalcanale, Enrico; Federici, Stefania; Sottini, Andrea; Bergese, Paolo; Tudisco, Cristina; Condorelli, Guglielmo G.
Angewandte Chemie, International Edition, 2014 , vol. 53, # 35 p. 9183 - 9188,6 Angewandte Chemie, 2014 , vol. 126, # 35 p. 9337 - 9342,6 Title/Abstract Full Text View citing articles Show Details
Spectra
NMR Spectroscopy (1)
146
Description (NMR Spectroscopy)
Nucleus (NMR Spectroscopy)
Solvents (NMR Spectroscopy)
Temperature (NMR Spectroscopy)
Frequency (NMR Spectroscopy)
Spectrum
31P
chloroform-d1
24.84 °C
400 MHz
Location
Reference
supporting information
Biavardi, Elisa; Menozzi, Daniela; Massera, Chiara; Dalcanale, Enrico; Federici, Stefania; Sottini, Andrea; Bergese, Paolo; Tudisco, Cristina; Condorelli, Guglielmo G.
Angewandte Chemie, International Edition, 2014 , vol. 53, # 35 p. 9183 - 9188,6 Angewandte Chemie, 2014 , vol. 126, # 35 p. 9337 - 9342,6 Title/Abstract Full Text View citing articles Show Details
Chemical Name: (14)C carbon tetrachloride; methamphetamine; mixture of
mixture (composition partially given) :
(14)C carbon tetrachloride (R)-(-)-methamphetamine
no reactions.
Reaxys Registry Number: 8188771 Type of Substance: mixture (composition partially given)
Hide Details Chemical Names and Synonyms (14)C carbon tetrachloride; methamphetamine; mixture of Composition (14)C carbon tetrachloride
(R)-(-)-methamphetamine
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Bioactivity Pharmacological Data (2) 1 of 2
2 of 2
Comment (Pharmacological Data)
Bioactivities present
Reference
Roberts, Stephen M.; Harbison, Raymond D.; James, Robert C.
Toxicology, 1995 , vol. 97, # 1-3 p. 49 - 57 Title/Abstract Full Text View citing articles Show Details
Effect (Pharmacological Data)
hepatotoxic
Species or TestSystem (Pharmacological Data)
ICR mouse
Sex
male
Route of Application
intraperitoneal
Kind of Dosing (Pharmacological Data)
0.005 ml/kg, i.p. <(14)C>CCl4, 1 μCi; methamphetamine 15 mg/kg, i.p. in 10 ml/kg saline 3 h after CCl4 dose
Exposure Period
0 - 120 min
Bioactivity (2)
1
(Pharmacological Data)
147
Method (Pharmacological Data)
adult ICR mice; 5-10 male, 30-35 g; administr. <(14)C>CCl4; methamphetamine administr. 3 h after dose CCl4; killed 0-120 min after methamphetamine dose; liver removed; homogen.; covalent binding of radiolabel to proteins and lipids was measured by Sipes
Further Details (Pharmacological Data)
compared with <(14)C>CCl4 alone; results presented as graph as pmoles bound per mg protein or mg lipid
Results
at all time points covalent binding of CCl4 to lipids in methamphetamine-treated mice was less than in mice administr. CCl4; covalent binding CCl4 to proteins was signif. greater in mice 60 min after methamphetamine dose, but unchanged at other time
Reference
Roberts, Stephen M.; Harbison, Raymond D.; James, Robert C.
Toxicology, 1995 , vol. 97, # 1-3 p. 49 - 57 Title/Abstract Full Text View citing articles Show Details
Chemical Name: methamphetamine; carbon tetrachloride; mixture of
mixture (composition partially given) :
tetrachloromethane (R)-(-)-methamphetamine
no reactions.
Reaxys Registry Number: 8188772 Type of Substance: mixture (composition partially given)
Hide Details Chemical Names and Synonyms methamphetamine; carbon tetrachloride; mixture of Composition
(R)-(-)-methamphetamine
tetrachloromethane
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Bioactivity Pharmacological Data (3) 1 of 3
2 of 3
Comment (Pharmacological Data)
Bioactivities present
Reference
Roberts, Stephen M.; Harbison, Raymond D.; James, Robert C.
Toxicology, 1995 , vol. 97, # 1-3 p. 49 - 57 Title/Abstract Full Text View citing articles Show Details
Effect (Pharmacological Data)
enzyme; examination of
Species or TestSystem (Pharmacological Data)
ICR mouse
Sex
male
Route of Application
intraperitoneal
Kind of Dosing (Pharmacological Data)
15 mg/kg, i.p. methamphetamine in 10 ml/kg saline; after 0 - 12 h 0.005 ml/kg, i.p. CCl4; control i.p. injection 10 ml/kg saline
Bioactivity (3)
1
3 of 3
148
Exposure Period (Pharmacological Data)
24 h
Method (Pharmacological Data)
adult ICR mice; 8-10 male, 30-35 g; administr. methamphetamine 15 mg/kg before (-3 h), with (0 h), or 3-12 h after dose CCl4 (0.005 ml/kg); killed; blood collected; necrogenic effect of title comp. assess. by serum alanine aminotransferase (ALT) activ.
Further Details (Pharmacological Data)
ALT activ. measured 24 h after CCl4 dose according to Bergmeyer; compared with control
Results
no signif. increas. in serum ALT activ. when methamphetamine cotreatment before 3 h or 6-12 h after dose CCl4(ca. 80-300 IU/l); cotreatm. methamphetamine with or 3 h after dose CCl4 signif. increas. ALT activ. (ca. 1080 or 1050 IU/l, resp.); control 24
Reference
Roberts, Stephen M.; Harbison, Raymond D.; James, Robert C.
Toxicology, 1995 , vol. 97, # 1-3 p. 49 - 57 Title/Abstract Full Text View citing articles Show Details
Effect (Pharmacological Data)
hepatotoxic
Species or TestSystem (Pharmacological Data)
ICR mouse
Sex
male
Route of Application
intraperitoneal
Kind of Dosing (Pharmacological Data)
pretreatment 2 mg/kg, i.p. methamphetamine in 10 ml/kg saline; administr. - 0.005 ml/kg, i.p. CCl4 with 5, 10, 15 mg/kg, i.p. methamphetamine; control i.p. injection 10 ml/kg saline
Exposure Period (Pharmacological Data)
24 h
Method (Pharmacological Data)
adult ICR mice; 8-10 male, 30-35 g; pretreat. methamphetamine 2 mg/kg at 7-day intervals for 5 weeks; after 1 week administr. CCl4 (0.005 ml/kg) with or without methamphetamine (5, 10, 15 mg/kg); killed; blood collected
Further Details (Pharmacological Data)
hepatic necrosis assessed through serum ALT (alanine aminotransferase) activity; ALT activ. measured 24 h after CCl4 dose according to Bergmeyer; control pretreatment saline; compared with control
Results
subchronic methamphetamine pretreatment signif. increased potentiation of CCl4 hepatotoxicity by all tested doses of methamphetamine; ratio ALT activ. for methamphetamine/saline pretreated mice was ca. 8, 18, 28 at 5, 10, 15 mg/kg methamphetamine, resp.
Reference
Roberts, Stephen M.; Harbison, Raymond D.; James, Robert C.
Toxicology, 1995 , vol. 97, # 1-3 p. 49 - 57 Title/Abstract Full Text View citing articles Show Details
mixture (composition partially given) :
tetrachloromethane (R)-(-)-methamphetamine Hide Details
Chemical Name: gadolinium chloride; carbon tetrachloride; methamphetamine; mixture of Reaxys Registry Number: 8188773 Type of Substance: mixture (composition partially given)
Chemical Names and Synonyms gadolinium chloride; carbon tetrachloride; methamphetamine; mixture of Composition tetrachloromethane
(R)-(-)-methamphetamine
no reactions.
Bioactivity (3)
1
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Bioactivity Pharmacological Data (3) 1 of 3
2 of 3
3 of 3
Comment (Pharmacological Data)
Bioactivities present
Reference
Roberts, Stephen M.; Harbison, Raymond D.; James, Robert C.
Toxicology, 1995 , vol. 97, # 1-3 p. 49 - 57 Title/Abstract Full Text View citing articles Show Details
Effect (Pharmacological Data)
hepatotoxic
Endpoint of Effect (Pharmacological Data)
ALT activity
Species or TestSystem (Pharmacological Data)
ICR mouse
Sex
male
Route of Application
intraperitoneal
Kind of Dosing (Pharmacological Data)
gadolinium chloride 10 mg/kg, i.v. in 10 ml/kg saline; CCl4 0.005 ml/kg i.p.; methamphetamine 15 mg/kg, i.p. in 10 ml/kg saline; control i.p. injection 10 ml/kg saline
Exposure Period (Pharmacological Data)
24 h
Method (Pharmacological Data)
adult ICR mice; 10 male, 30-35 g; pretreated gadolinium chloride; administr. CCl4 (0.005 ml/kg) with or without methamphetamine (15 mg/kg); killed; blood collected; necrogenic effect of title comp. assess. by serum alanine aminotransferase (ALT) activ.
Further Details (Pharmacological Data)
ALT activ. measured 24 h after CCl4 dose according to Bergmeyer; compared with control
Results
pretreatment with gadolinium chlorid did not affect minimal toxicity of CCl4 alone and ALT activ.; substantially diminished the potentiation of CCl4 hepatotoxicity by methamphetamine; presented as graph
Reference
Roberts, Stephen M.; Harbison, Raymond D.; James, Robert C.
Toxicology, 1995 , vol. 97, # 1-3 p. 49 - 57 Title/Abstract Full Text View citing articles Show Details
Effect (Pharmacological Data)
hepatotoxic
Species or TestSystem (Pharmacological Data)
ICR mouse
Sex
male
Route of Application
intraperitoneal
Kind of Dosing (Pharmacological Data)
gadolinium chloride 10 mg/kg, i.v. in 10 ml/kg saline; CCl4 0.005 ml/kg i.p.; methamphetamine 15 mg/kg, i.p. in 10 ml/kg saline; control i.p. injection 10 ml/kg saline
Exposure Period (Pharmacological Data)
24 h
Method (Pharmacological Data)
adult ICR mice; 10 male, 30-35 g; pretreated gadolinium chloride; administr. CCl4 (0.005 ml/kg) with or without methamphetamine (15 mg/kg); killed; liver removed; sections 4-6 μm thick; stained with hematoxylin and eosin
Further Details (Pharmacological
examined histopathology by light microscopy
Data)
149
Results
pretreatment with gadolinium chloride CCl4-induced necrotic lesions were typically 1/3 to 1/2 the size of those in mice without gadolinium pretriatment; present necrotic foci; many of the lobules had normal, or nearly normal, histology
Reference
Roberts, Stephen M.; Harbison, Raymond D.; James, Robert C.
Toxicology, 1995 , vol. 97, # 1-3 p. 49 - 57 Title/Abstract Full Text View citing articles Show Details
mixture (composition partially given) :
(R)-(-)-methamphetamine carbidopa, catechol-O-methyl transferase (COMT) inhibitor, levodopa; mixture of
Reaxys Registry Number: 11400535 Type of Substance: mixture (composition partially given)
no reactions.
Bioactivity (2)
1
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Composition (R)-(-)-methamphetamine
carbidopa, catechol-O-methyl transferase (COMT) inhibitor, levodopa; mixture of
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Bioactivity Pharmacological Data (2) 1 of 2
Comment (Pharmacological Data)
Bioactivities present
Reference
Caron, Marc G.; Sotnikova, Tatyana D.; Gainetdinov, Raul R.
Patent: US2007/27208 A1, 2007 ; Title/Abstract Full Text Show Details
2 of 2
Effect (Pharmacological Data)
locomotor activity
Species or TestSystem (Pharmacological Data)
DAT-KO mouse
Sex
male and female
Route of Application
intraperitoneal
Method (Pharmacological Data)
Experimental We report here that the pharmacologic inhibition of the rate-limiting enzyme of DA synthesis, TH, almost immediately depletes brain DA to undetectable levels in DAT-KO mice and induces a transient recapitulation of essentially all PD symptoms for up to 16 h. DA-deficient DAT-KO mice (DDD mice) thus represent an acute PD model that is useful for studying the efficacy of compounds that potentially can restore control of locomotion in the absence of any contribution of the dopaminergic system. By using this approach, we found that several amphetamine derivatives can counteract the behavioral manifestations of severe DA deficiency, suggesting that, in addition to well-known DA-mediated effects, amphetamine-like compounds can also affect motor functions in a DA- and DAT-independent manner. Materials and Methods Animals. DAT-KO mice were generated as previously described [11]. Animal care was in accordance with the Guide for Care and Use of Laboratory Animals (National Institutes of Health publication No.865-23, Bethesda, Md., United States) with an approved protocol from the Duke University Institutional Animal Care and Use Committee. C57BL/6J3129Sv/J hybrid WT and DAT-KO mice, 3-5 mo old, of both sexes were used. None of animals used in these studies had the neurodegenerative phenotype sporadically observed in DAT-KO mice [60]. Drugs. Drugs or saline (0.9percent NaCl) were administered intraperitoneally (IP) or subcutaneously (SC) in a volume of 10 ml/kg. The drags were either from Sigma (St. Louis, Mo., United States) or supplied by the National Institute of Drug Abuse (NIDA). Drugs provided by the NIDA Drug Supply Program included: (+/-)-MDMA, (+)-MDMA, (+/-)-6-OH-MDA, (+/-)-MDA, (+/-)-MDE, (+)-MDE, (-)-MDE, and AFT (alpha-ethyl-tryptamine acetate). Neurochemical assessments. Striatal tissue contents of DA and frontal cortical tissue levels of NE were assessed using HPLC-EC (high performance liquid
chromatography with electrochemical detection) as described [8]. In vivo microdialysis measurements of striatal extracellular DA levels in freely moving mice were performed at least 24 h after implantation of a microdialysis probe as described previously [50]. Dialysate samples were assayed for DA using HPLC-EC. Behavioral methods. Locomotor activity of littermate WT and DATKO mice was measured in an Omnitech CCDigiscan (Accuscan Instruments, Columbus, Ohio United States) activity monitor under bright illumination [83]. All behavioral experiments were performed between 10:00 AM and 5:00 PM. Activity was measured at 5-min intervals, To evaluate the effects of drugs on motor behaviors, mice were placed into activity monitor chambers (20.x.20 cm) for 30 min and then treated with αMT (250 mg/kg IP). A drug or combination of drugs were injected 1 h after αMT administration, and various parameters of locomotor activity were monitored for up to 3 h. In cumulative dosing experiments, animals were treated with increasing doses of drugs after a 1-h interval. For the akinesia test, the mouse is held by the tail so that it is standing on forelimbs only and moving on its own. The number of steps taken with both forelimbs was recorded during a 30-s trial [57]. The presence of catalepsy was determined and measured by placing the animal's forepaws on a horizontal wooden bar (0.7 cm in diameter), 4 cm above the tabletop. The time until the mouse removed both forepaws from the bar was recorded, with a maximum cut-off time of 3 min [53]. In the grasping test of muscular rigidity, the mouse is suspended by its forelimbs on a metal rod (diameter: 0.25 cm) positioned approximately 20 cm above the table. The time the animal remains on the rod (maximum 1 min) was noted [58]. To assess rigidity in a bracing task, the number of steps taken with each forelimb when the mouse is pushed sideways over a distance of 50 cm was recorded [57]. Tremor was scored visually in mice using the rating scale [54]: 0, no tremor; 1, occasional isolated twi Results
potent synergistic effect of L-DOPA/carbidopa and METH was observed; figure is given
Location
Page/Page column 3-4; 12-15; sheet 10
Reference
Caron, Marc G.; Sotnikova, Tatyana D.; Gainetdinov, Raul R.
Patent: US2007/27208 A1, 2007 ; Title/Abstract Full Text Show Details
150
Reaxys Registry Number: 26574692 Type of Substance: mixture (composition completely given)
mixture (composition completely given) :
d-N,a-dimethylphenethylamine 1,3-di-o-tolyl-guanidine
no reactions.
Bioactivity (2)
1
Bioactivity (1)
1
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Composition d-N,a-dimethylphenethylamine (0.0001 - 10 μmol)
1,3-di-o-tolyl-guanidine (0.01 - 1000 μmol)
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Bioactivity Pharmacological Data (2) 1 of 2
2 of 2
151
Comment (Pharmacological Data)
Bioactivities present
Reference
Kaushal, Nidhi; Robson, Matthew J.; Rosen, Abagail; McCurdy, Christopher R.; Matsumoto, Rae R.
European Journal of Pharmacology, 2014 , vol. 724, # 1 p. 193 - 203 Title/Abstract Full Text View citing articles Show Details
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Kaushal, Nidhi; Robson, Matthew J.; Rosen, Abagail; McCurdy, Christopher R.; Matsumoto, Rae R.
European Journal of Pharmacology, 2014 , vol. 724, # 1 p. 193 - 203 Title/Abstract Full Text View citing articles Show Details
mixture (composition partially given) :
2-[(diphenylmethyl)sulfinyl]acetamide d-N,a-dimethylphenethylamine
Reaxys Registry Number: 27703154 Type of Substance: mixture (composition partially given)
no reactions.
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Composition d-N,a-dimethylphenethylamine
2-[(diphenylmethyl)sulfinyl]acetamide
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Bioactivity Pharmacological Data (1) 1 of 1
152
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Gonzlez, Betina; Raineri, Mariana; Cadet, Jean Lud; Garca-Rill, Edgar; Urbano, Francisco J.; Bisagno, Veronica
Neuropharmacology, 2014 , vol. 87, p. 188 - 197 Title/Abstract Full Text View citing articles Show Details
mixture (composition partially given) :
6-D(−)-α-(4-ethyl-2,3-dioxo-1-piperazinylcarbonylamino)-αphenylacetamidopenicillinic acid 2-diethylaminoethyl ester hydrochloride 2-diethylaminoethyl 2-[(2,6-dichlorophenyl)amino]benzeneacetate hydrochloride (RS)-N-[1-(1-benzothien-2-yl)ethyl]-N-(2-diethylaminoacetyloxy)urea hydrochloride metaproterenol triacetate hydrochloride (R)-(-)-methamphetamine
Reaxys Registry Number: 27922949 Type of Substance: mixture (composition partially given)
no reactions.
Hide Details
Composition (R)-(-)-methamphetamine
2-diethylaminoethyl 2-[(2,6dichlorophenyl)amino]benzeneacetate hydrochloride
6-D(−)-α-(4-ethyl-2,3-dioxo-1piperazinylcarbonylamino)-αphenylacetamidopenicillinic acid 2diethylaminoethyl ester hydrochloride
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Identification Bioactivity (1) Other Data (15)
1
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metaproterenol triacetate hydrochloride
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Identification Substance Label (1) Label
Reference
3; 4; 5
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
Bioactivity Pharmacological Data (1) 1 of 1
Location
Paragraph
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
Other Data Use (15) Use Pattern
Location
Reference
Pharmaceuticals
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
allergic conjunctivitis
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
allergic rhinitis
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
asthma
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
chronic bronchitis
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
chronic obstructive pulmonary disease
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
cystic fibrosis
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
emphysema
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
itchiness
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
lower, and upper respiratory tract infections
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
pneumonia
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
pulmonary condition
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
pulmonary fibrosis
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
runny nose
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
sarcoidosis
Page/Page column 75-78
YU, Chongxi; XU, Lina
Patent: US2015/72961 A1, 2015 ; Title/Abstract Full Text Show Details
Chemical Name: (S)-N-methylamphetamine hydrochloride Reaxys Registry Number: 28371209
Molecular Formula: C10H15N*(x)ClH Linear Structure Formula: C10H15N*xClH InChI Key: TWXDDNPPQUTEOV-FVGYRXGTSA-N
153
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no reactions.
Identification Physical Data (1)
1
(S)-N-methylamphetamine hydrochloride Identification Patent-Specific Data (1) Location in Patent
Reference
Page/Page column
CHEMAPOTHECA, LLC; Meckler, Harold; Gregg, Brian Thomas; Yang, Jie
Patent: US2015/183716 A1, 2015 ; Title/Abstract Full Text Show Details
Physical Data Melting Point (1) Melting Point
Location
Reference
172 - 175 °C
Paragraph 0159
CHEMAPOTHECA, LLC; Meckler, Harold; Gregg, Brian Thomas; Yang, Jie
Patent: US2015/183716 A1, 2015 ; Title/Abstract Full Text Show Details
154
Reaxys Registry Number: 28633412 Type of Substance: mixture (composition partially given)
mixture (composition partially given) :
methamphetamin chlordiazepoxide
no reactions.
Bioactivity (1)
1
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Show Related Substances
Composition methamphetamin
chlordiazepoxide
155
mixture (composition partially given) :
Methamphetamin thalidomide
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Reaxys Registry Number: 28681688 Type of Substance: mixture (composition partially given)
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Composition thalidomide
Methamphetamin
no reactions.
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Bioactivity Pharmacological Data (1) 1 of 1
156
Comment (Pharmacological Data)
Bioactivities present
Reference
Astarita, Giuseppe; Avanesian, Agnesa; Grimaldi, Benedetto; Realini, Natalia; Justinova, Zuzana; Panlilio, Leight V.; Basit, Abdul; Goldberg, Steven R.; Piomelli, Daniele
PLoS ONE, 2015 , vol. 10, # 2 art. no. E0116961 Title/Abstract Full Text View citing articles Show Details
Reaxys Registry Number: 28681689 Type of Substance: mixture (composition partially given)
mixture (composition partially given) :
Methamphetamin L-cycloserine
no reactions.
Bioactivity (1)
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Composition L-cycloserine
Methamphetamin
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Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
Bioactivities present
Reference
Astarita, Giuseppe; Avanesian, Agnesa; Grimaldi, Benedetto; Realini, Natalia; Justinova, Zuzana; Panlilio, Leight V.; Basit, Abdul; Goldberg, Steven R.; Piomelli, Daniele
PLoS ONE, 2015 , vol. 10, # 2 art. no. E0116961 Title/Abstract Full Text View citing articles Show Details
1
157
Reaxys Registry Number: 29397809 Type of Substance: mixture (composition partially given)
mixture (composition partially given) :
S-methamphetamine hydrochloride 3'-azido-2',3'-deoxythymidine Nevirapine Saquinavir
no reactions.
Bioactivity (2)
1
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Composition 3'-azido-2',3'-deoxythymidine
Nevirapine
S-methamphetamine hydrochloride
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Saquinavir
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Bioactivity Pharmacological Data (2) 1 of 2
2 of 2
Comment (Pharmacological Data)
Bioactivities present
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
158
Reaxys Registry Number: 29397810 Type of Substance: mixture (composition partially given)
mixture (composition partially given) :
S-methamphetamine hydrochloride 3'-azido-2',3'-deoxythymidine
no reactions.
Bioactivity (2)
1
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Composition S-methamphetamine hydrochloride
3'-azido-2',3'-deoxythymidine
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Bioactivity Pharmacological Data (2) 1 of 2
2 of 2
159
Comment (Pharmacological Data)
Bioactivities present
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
mixture (composition partially given) :
Nevirapine S-methamphetamine hydrochloride
Reaxys Registry Number: 29397811 Type of Substance: mixture (composition partially given)
no reactions.
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Composition Nevirapine
S-methamphetamine hydrochloride
Bioactivity (2)
1
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Bioactivity Pharmacological Data (2) 1 of 2
2 of 2
160
Comment (Pharmacological Data)
Bioactivities present
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
Reaxys Registry Number: 29397812 Type of Substance: mixture (composition partially given)
mixture (composition partially given) :
Saquinavir S-methamphetamine hydrochloride
no reactions.
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Composition S-methamphetamine hydrochloride
Bioactivity
Saquinavir
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Bioactivity (2)
1
Pharmacological Data (2) 1 of 2
2 of 2
161
Comment (Pharmacological Data)
Bioactivities present
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
Reaxys Registry Number: 29479297 Type of Substance: mixture (composition partially given)
mixture (composition partially given) :
S-methamphetamine hydrochloride human immunodeficiency virus type 1 BaL gp120
no reactions.
Bioactivity (1)
1
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Composition S-methamphetamine hydrochloride
human immunodeficiency virus type 1 BaL gp120
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Bioactivity Pharmacological Data (1) 1 of 1
162
Comment (Pharmacological Data)
Bioactivities present
Reference
Sanchez, Ana B.; Varano, Giuseppe P.; De Rozieres, Cyrus M.; Maung, Ricky; Catalan, Irene C.; Dowling, Cari C.; Sejbuk, Natalia E.; Hoefer, Melanie M.; Kaul, Marcus
Antimicrobial Agents and Chemotherapy, 2016 , vol. 60, # 1 p. 168 - 179 Title/Abstract Full Text View citing articles Show Details
mixture (composition partially given) :
low-affinity anti-(+)-methamphetamine monoclonal antibody 6H8 Methamphetamin
Reaxys Registry Number: 29480448 Type of Substance: mixture (composition partially given)
no reactions.
Bioactivity (1)
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Composition Methamphetamin
low-affinity anti-(+)-methamphetamine monoclonal antibody 6H8
1
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Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
The Board of Trustees of the University of Arkansas; Owens, Samuel M.; Carroll, Frank Ivy; Abraham, Philip
Patent: US9303092 B2, 2016 ; Title/Abstract Full Text Show Details
163
mixture (composition partially given) :
high-affinity anti-(+)-methamphetamine monoclonal antibody 6H4 Methamphetamin
Reaxys Registry Number: 29480450 Type of Substance: mixture (composition partially given)
no reactions.
Bioactivity (1)
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Composition Methamphetamin
high-affinity anti-(+)-methamphetamine monoclonal antibody 6H4
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Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
The Board of Trustees of the University of Arkansas; Owens, Samuel M.; Carroll, Frank Ivy; Abraham, Philip
Patent: US9303092 B2, 2016 ;
1
Title/Abstract Full Text Show Details
164
Reaxys Registry Number: 29480452 Type of Substance: mixture (composition partially given)
mixture (composition partially given) :
anti-phencyclidine monoclonal antibody Fab fragment Methamphetamin
no reactions.
Bioactivity (1)
1
Bioactivity (1)
1
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Composition anti-phencyclidine monoclonal antibody Fab fragment
Methamphetamin
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Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
The Board of Trustees of the University of Arkansas; Owens, Samuel M.; Carroll, Frank Ivy; Abraham, Philip
Patent: US9303092 B2, 2016 ; Title/Abstract Full Text Show Details
165
mixture (composition partially given) :
anti-d-methamphetamine-specific monoclonal antibody Fab fragment Methamphetamin
Reaxys Registry Number: 29480453 Type of Substance: mixture (composition partially given)
no reactions.
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Composition Methamphetamin
anti-d-methamphetamine-specific monoclonal antibody Fab fragment
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Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
The Board of Trustees of the University of Arkansas; Owens, Samuel M.; Carroll, Frank Ivy; Abraham, Philip
Patent: US9303092 B2, 2016 ; Title/Abstract Full Text Show Details
166
mixture (composition partially given) :
high-affinity anti-(+)-methamphetamine, (+)-amphetamine, (+)-3,4methylenedioxymethamphetamine monoclonal antibody 4G9 Methamphetamin
Reaxys Registry Number: 29480455 Type of Substance: mixture (composition partially given)
no reactions.
Bioactivity (1)
1
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Composition high-affinity anti-(+)-methamphetamine, (+)-amphetamine, (+)-3,4-methylenedioxymethamphetamine monoclonal antibody 4G9
Methamphetamin
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Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
The Board of Trustees of the University of Arkansas; Owens, Samuel M.; Carroll, Frank Ivy; Abraham, Philip
Patent: US9303092 B2, 2016 ; Title/Abstract Full Text Show Details
167
mixture (composition partially given) :
anti-(+)-methamphetamine monoclonal antibody mAb6H7 Methamphetamin
Reaxys Registry Number: 29480456 Type of Substance: mixture (composition partially given)
no reactions.
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Composition Methamphetamin
anti-(+)-methamphetamine monoclonal antibody mAb6H7
Bioactivity (1)
1
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Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
The Board of Trustees of the University of Arkansas; Owens, Samuel M.; Carroll, Frank Ivy; Abraham, Philip
Patent: US9303092 B2, 2016 ; Title/Abstract Full Text Show Details
168
Reaxys Registry Number: 29480457 Type of Substance: mixture (composition partially given)
mixture (composition partially given) :
anti-(+)-methamphetamine monoclonal antibody mAb9B11 Methamphetamin
no reactions.
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Composition Methamphetamin
anti-(+)-methamphetamine monoclonal antibody mAb9B11
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Bioactivity Pharmacological Data (1) 1 of 1
Comment (Pharmacological Data)
physiological behaviour discussed
Reference
The Board of Trustees of the University of Arkansas; Owens, Samuel M.; Carroll, Frank Ivy; Abraham, Philip
Patent: US9303092 B2, 2016 ;
Bioactivity (1)
1
Title/Abstract Full Text Show Details