•
All tissues are involved to some extent in metabolism
•
A drug needs to be changed from a lipid form to be eliminated.
•
Metabolism of a drug follows either phase 1 or phase 2
Questions 1. The study of absorption, distribution and elimination is called a. Pharmacodynamics b. Drug tolerance c. Pharmacokinetics d. Drug efficacy The answer is c, pharmacokinetics 2. Pharmacokinetics refers to the relationship of a drug a. Dose to dose concentration in blood plasma b. Dose to drug at the receptor site c. Concentrations to drug effect d. Dose to drug effect The answer is a, dose to dose concentration in blood plasma 3. We measure drug levels in the plasma because it is the same as the body tissues. a. True b. False The answer is a, true 4. Which of the following is true about cell membranes? a. Cell membranes are basically impervious to water b. A drug can be transported across a membrane in an active fashion c. Central nervous system membranes are more impervious to allow cerebral spinal fluid in d. The ionized form of a drug is most likely to cross The answer is b, a drug can be transported across a cell membrane in an active fashion
