Frontier Pharma: Parkinsons Disease - Identifying and Commercializing First-in-Class Innovation

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Category : Healthcare

Frontier Pharma: Parkinsons Disease - Identifying and Commercializing First-in-Class Innovation


Synopsis The Parkinsons disease (PD) pipeline currently has 302 products in active development across all stages, but a stark contrast between the mechanisms of action employed in the current market and the pipeline is evident. Where the market relies on symptomatic treatments that target neuromodulatory receptors, the pipeline shows a diverse range of neuroprotective therapies targeting dysfunctional disease processes.

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Summary PD is a complex and multifaceted disease with a complex interplay between different pathological processes. Enormous research efforts and significant technological advances have furthered knowledge of the neuroanatomy of the basal ganglia and of the fundamental processes underlying neurodegeneration, helped by the ongoing identification of susceptibility genes and causative genes in familial PD. Although the exact mechanisms that initiate onset remain unclear, these insights have been translated into the pool of novel therapeutic targets, which may potentially become disease-modifying therapies by aligning to the disease processes and some genetic determinants of PD.


Table of contents 1.1 List of Tables 3 1.2 List of Figures 3 2 Executive Summary 5 2.1 Highly Innovative and Diverse Pipeline 5 2.2 Alignment of Innovation to Disease Processes and Genetics 5 2.3 Deals Landscape Present Substantial Investment Opportunities 5


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Frontier Pharma: Parkinsons Disease - Identifying and Commercializing First-inClass Innovation Published: Dec 2014 – 121 Pages

The Parkinsons disease (PD) pipeline currently has 302 products in active development across all stages, but a stark contrast between the mechanisms of action employed in the current market and the pipeline is evident Price

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