http://www.bimeda.ie/docs/cadocs/POTENSULF___1POT001_1POT002_1POT003___OCTOBER_2010

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Product Identifier: POTENSULF

MATERIAL SAFETY DATA SHEET SECTION 1 – PRODUCT IDENTIFICATION AND USE MANUFACTURER’S NAME:

BIMEDA-MTC ANIMAL HEALTH INC.

SUPPLIER’S NAME:

BIMEDA-MTC ANIMAL HEALTH INC.

STREET ADDRESS:

420 BEAVERDALE ROAD

STREET ADDRESS:

420 BEAVERDALE ROAD

CITY AND PROVINCE:

CAMBRIDGE, ONTARIO

CITY AND PROVINCE:

CAMBRIDGE, ONTARIO

POSTAL CODE:

N3C 2W4

POSTAL CODE:

N3C 2W4

TELEPHONE #

519-654-8000

TELEPHONE #

519-654-8000

EMERGENCY PHONE #

Canutech 613-996-6666

EMERGENCY PHONE #

Canutech 613-996-6666

CHEMICAL FORMULA:

Sulfadoxine = 200 mg/mL; Trimethoprim = 40 mg/mL

PRODUCT USE:

For Use in Animals Only. Sulfonamide antibacterial agent for veterinary use.

PRODUCT CODE:

1POT001, 1POT002, 1POT003

SECTION 2 – COMPOSITION / INFORMATION ON INGREDIENTS COMPONENT

% (W/W)

CAS NUMBER

Sulfadoxine (1 - (5, 6-dimethoxy-4pyrimidinly) sulfamilamide) Trimethoprim Aqueous solution of glycerine formal

PRODUCT IDENTIFICATION NUMBER (PIN)

2447-56-6

738-70-5

SECTION 3 – PHYSICAL DATA PHYSICAL STATE:

ODOUR AND APPEARANCE:

ODOUR THRESHOLD (ppm):

Odour: N/D Physical Form: Clear, Yellow Solution VAPOUR PRESSURE (mm Hg):

VAPOUR DENSITY (Air = 1):

EVAPORATION RATE (Ether = 1):

BOILING POINT (DEG.C):

FREEZING POINT (DEG. C):

CRITICAL TEMPERATURE:

pH (100%):

SPECIFIC GRAVITY (H2O = 1):

SOLUBIITY IN WATER:

OTHER:

Miscible in water

Do not use if cloudy or dark brown in colour.

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Product Identifier: POTENSULF SECTION 4 – FIRE AND EXPLOSION DATA FLAMMABLE: No unusual fire risk. IF YES, UNDER WHICH CONDITIONS: MEANS OF EXTINCTION: All types of extinguishers are recommended, especially water mist. SPECIAL PROCEDURES: Fire fighters should wear self-contained breathing apparatus. Emits toxic fumes (CO and CO2)

under fire conditions. FLASHPOINT (Deg. C) AND METHOD:

UPPER FLAMMABLE LIMIT (% BY VOLUME):

LOWER FLAMMABLE LIMIT (% BY VOLUME):

None

Not applicable

Not applicable

AUTOIGNITION TEMPERATURE (DEG. C):

HAZARDOUS COMBUSTION PRODUCTS:

SENSITIVITY TO IMPACT:

SENSITIVITY TO STATIC DISCHARGE:

SECTION 5 – REACTIVITY DATA CHEMICAL STABILITY – (IF NO, UNDER WHICH CONDITIONS?)

Stable; Hazardous Polymerization will not occur. INCOMPATIBILITY WITH OTHER SUBSTANCES (IF YES, WHICH ONES?) REACTIVITY, AND UNDER WHAT CONDITIONS? HAZARDOUS DECOMPOSITION PRODUCTS:

SECTION 6 – TOXICOLOGICAL PROPERTIES ROUTE OF ENTRY:

Skin Contact: ( ) Inhalation Acute: ( )

Skin Contact: ( ) Inhalation Chronic: ( )

Eye Contact: ( ) Ingestion: ( )

EFFECTS OF ACUTE EXPOSURE TO MATERIAL:

May cause irritation to eyes and skin INHALATION: INGESTION: OTHER:

Ingestion of large amounts may cause stomach distress, nausea or vomiting. Possible allergic reaction to dust if inhaled, ingested or in contact with skin. Material may be irritating to mucous membranes and respiratory tract. This toxicity information if based on the active ingredient ‘Sulfadoxine’.

EFFECTS OF CHRONIC EXPOSURE: (SPECIFY SPECIES AND ROUTE):

* Toxicity information is based on the active ingredient ‘Sulfadoxine’

EXPOSURE LIMITS (ACGIH TLV’S):

LD50 Oral LD50: 5200 mg/kg (mice). Interperitoneal LD50: 2900 mg/kg (mice) Sub-cutaneous LD50: 2900 mg/mL (Mice)

LC50

IRRITANCY:

Respiratory Tract Sensitization: Sensitizing Capability: Reproductive Effects:

Carcinogenicity: Synergistic Materials:

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Product Identifier: POTENSULF SECTION 7 – PREVENTATIVE MEASURES PERSONAL PROTECTIVE EQUIPMENT: Follow good clinical practices. GLOVES (Specify): RESPIRATOR (Specify):

EYES (Specify):

FOOTWEAR(Specify):

OTHER (Specify):

CLOTHING (Specify):

ENGINEERING CONTROLS: LEAK AND SPILL PROCEDURES: Spills can be removed with a suitable absorbent. WASTE DISPOSAL: Dispose in accordance with local regulations at a government approved waste management site or

incinerator. STORAGE AND HANDLING REQUIREMENTS: Preventative measures for handling are like those for most chemicals,

observe good personal hygiene. Avoid contact with skin and eyes. Wash hands after work. Do not eat, drink or smoke when handling. Store in air tight containers, away from other chemicals. Store at room temperature, below 25 degrees Celsius. Protect from light. Keep this and all drugs out of the reach of children.

SECTION 8 – FIRST AID MEASURES Consult a doctor and/or nearest Poison Control Centre for all extreme exposures. Except minor instances of inhalation or skin contact. Eyes: Immediately flush eyes with plenty of water and seek medical attention if any irritation or numbness persists. Skin: Wash affected areas with soap and water. Ingestion: Flush out mouth with water. Immediately seek medical attention and bring this safety data sheet along. Note to Physician: Persons developing hypersensitivity reactions much receive immediate medical attention. Sulfonamide drugs may cause kidney damage when overdoses are taken. The Sulfonamides bear certain chemical similarities to some goitrogens, diuretic and oral hypoglycemia agents. Goiter production, diuresis and hypoglycemia have occurred rarely in patients receiving sulfonamide. Inhalation:

SECTION 9 – PREPARATION DATA DATE: DATE REVISED:

August 2002 August 2006, October 2010

TELEPHONE NUMBER:

519-654-8000

Information for this material safety data sheet was obtained from sources considered technically accurate and reliable. While every effort has been made to ensure full disclosure of product hazards, in some cases data is not available and is so stated. Since conditions of actual product use are beyond the control of the supplier, it is assumed that user of this material has been fully trained according to the mandatory requirements of WHMIS. No warranty, expressed or implied, is made and supplier will not be liable for any losses, injuries or consequential damages which may result from the use of or reliance on any information contained in this form. If user requires independent information on ingredients in this or any other material, we recommend contact supplier.

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