Bürkert | precision partners for biotechnology needs

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Bürkert expertise Customer references

PRODUCTS AND SOLUTIONS

Applications Precise gas control in laboratories PRODUCTS AND SOLUTIONS

Your precision partner for your Biotechnology needs

Precise media control in laboratories

We make ideas flow.


/ Precise dosing and media protection for accurate test results / A variety of systems and components are used to precisely control, regulate and measure fluids and gases inside laboratory devices. BĂźrkert supplies and develops suitable components and systems for various applications. Complete solutions are also possible to ensure that everything, from your media supply to your reagent and sample dosing, as well as the analysis unit, cleaning and waste handling, is under control. The media supply ensures that adequate amounts of fluids and gases are distributed inside laboratory devices. BĂźrkert solutions represent the interface between the external media supply and the device. It is essential that the defined parameters such as pressure, temperature and flow rate be maintained. Flawless coordination between the individual BĂźrkert components ensures that processes run perfectly.


In the system solution, all the components complement each other perfectly. Low manufacturing tolerances ensure the same switching behaviour for all valves – even after replacement

BĂźrkert expertise

Time-pressure dosing accelerates your dosing process and allows your analytical device to work more efficiently and effectively. At the same time, dosing is carried out in a reproducible manner along with flexible dosing quantities.

Customer references

RELIABLE PROCESSES

Applications

INCREASED SAMPLE THROUGHOUT

PRODUCTS AND SOLUTIONS

The low power consumption of the valve also means less heat is generated. The design of the valve also ensures that any heat generated is mainly released into the environment. Heat input into the medium is therefore reduced to a minimum.

Precise gas control in laboratories

Regardless of the pressure, the valves switch extremely fast and precise. This prevents overdosing or underdosing, ensuring consistent and reliable results. Your samples stay clean and you receive highly accurate test results.

PRODUCTS AND SOLUTIONS

UNDAMAGED MEDIA

Precise media control in laboratories

ACCURATE TEST RESULTS


Products and systems for laboratory media control and dosing applications

Type 7615 Micro-dosing unit • Diaphragm pump with active inlet and outlet valves, bidirectional with autonomous intake

Type 6624 TwinPower Rocker valve • Optimised size-to-performance ratio enables ideal use of building space

• Precise dosing of minimal amounts of fluid with high dosing precision and reproducibility (< ±3.5%)

• Equipped with gas impermeable diaphragm that isolates the medium and actuator from one another, thereby protecting both

Type 0127 Rocker valve

Type 6650 Flipper valve

• Special combination of low internal volume and virtually cavity-free design

• Very fast and precise switching increases repeatability of dosing

• Maximum repeatability ensures reliable dosing results

• Enhanced safety thanks to extremely long life time of up to 200 million switching cycles

Type 6628 Rocker valve • The 3/2-way valve enables high flow rates • The established rocker technology provides absolute back-pressure leak-tightness

Type 6712 Whisper valve Plunger with isolating diaphragm • ideal for installation in extremely small spaces or on moving parts • Silent switching for a more pleasant laboratory working environment

Type 0330 Pivoted armature Solenoid valve • Achieves high flow rates with an orifice of up to 5mm • Increased safety thanks to maintenance-free pivoted armature technology

Type 6724 Whisper valve Rocker valve • Reliable media separation ensures high resistance to chemicals • Excellent rinsability prevents cross-contamination


Modular system for syringe pump dosing

Customised valve

Pressure regulator/controller

Customised system solution

• Reduced workload during system service thanks to internal system check

• Flexible and versatile system

• FDA-compliant materials

• Repeatable and accurate dosing of liquids in the µl range

• Reliable regulation of flow rates

• High-pressure version

• Response time in milliseconds

• Our team of experts have years of experience working with biotechnology and pharmaceutical companies.

• Design tailored to the application reducing complexity of assembly

• Designed to prevent and detect air bubbles

• Extremely reduced internal volume

• Digital communication for easy integration into your fieldbus network

Micro-dosing unit • Hygiene and FDA conformity

Variants with specialised modifications such as

• Maximum process reliability thanks to low internal volumes and excellent rinsability • Integrated I²C bus control and display

• CAD-based animations and simulations are used to validate design, before prototypes are built.

Bürkert expertise

• Design of fluid channels ensures smooth flow for reagents and samples reducing shear forces

• Solution made to order for each application thanks to surpassing expertise and experience

• Helps reduce cost for the Waste Line

• Ultra-short reaction times for high throughput

Customer references

• Very long life cycle and low-maintenance

• Enhanced safety, easier maintenance and fewer weak points thanks to less interfaces

Applications

• High throughput thanks to extremely short switching times

• Less need for maintenance thanks to extremely long life cycle of up to 500 million switching cycles

16-Fold pressure controller

PRODUCTS AND SOLUTIONS

• Unique combination of compact size and appropriately large orifice

Manifold

Precise gas control in laboratories

• Precise and fast switching enables high reproducibility

3-in-1 Manifold

PRODUCTS AND SOLUTIONS

Type 6011 Plunger valve

Precise media control in laboratories

Type 6114 Flipper valve


/ Be it a research laboratory or an experimental facility / When it comes to fermentation, gases and liquids must be precisely controlled. Fermentation in the laboratory places high demands on the bioreactors or fermenters used. Whether you are cultivating micro-organisms or cells – the materials installed must be compliant and approved, the process data documented and evaluable. Having everything under control makes all the difference for operators – which is why they insist on processes that are fully transparent. Only by doing so can you harvest the product you need in the required quality at the end of the process. In addition to safe and clean working methods, the reproducibility of the processes is key. Why is it so important? If you want to create an identical product at a later date, you need verified and accessible data for precise gas dosing. In addition, you should be able to selectively influence the fermentation process at any time to optimise the growth of the final product. With the right mixture, you can control gases seamlessly.


HIGH QUALITY

MFCs make your processes reproducible with precise and repeatable accurate sensors and proportional valve technology.

High-quality materials are used during production to guarantee reliable product quality.

GOOD TO GO

AVAILABLE

With the MFCs, you can rely on compact components that are ready for immediate use. Rapid start-up is possible thanks to simple wiring and configuration.

The process data is permanently available, which enables 24/7 control and monitoring of the fermentation process.

SCALABLE

TRACEABLE

High turn-down ratio (> 100:1) allow instant adjustment of gas control to the respective process stage.

B端rkert products conform to acceptance test certificate 3.1, which means that the origin of the stainless steel used can be clearly documented and clearly traced.

B端rkert expertise

REPRODUCIBLE

Customer references

Direct-measuring thermal and direct-acting proportional valves make the B端rkert solution ultra-precise and ensure swift response times.

Applications

MFCs by B端rkert are biocompatible and conform to USP Class VI. This offers guaranteed process reliability to you, the manufacture.

PRODUCTS AND SOLUTIONS

PRECISE

Precise gas control in laboratories

BIOCOMPATIBLE



• Suitable for a wide range of applications • High accuracy and repeatability • Especially designed for use in harsh environments due to high protection class and explosion-proof

Future-proof automation solutions

• Particularly efficient mass flow controllers for use in multi-MFC systems. • Easy integration and a high level of efficiency if a plant is equipped with a higher number of flow control loops.

PRODUCTS AND SOLUTIONS

Type 8746 Mass flow controller for multi-channel gas flow systems (multi-MFC system)

Bürkert expertise

• Thermal inline sensor located directly in the main gas stream provides for very fast response times while causing very low pressure drop.

Customer references

• CANopen based Bürkert system bus (büS) is suitable for the integration into existing CANopen networks, as well as Industrial Ethernet or fieldbus networks in combination with the fieldbus gateway of Type ME43

Applications

• Suitable for mass flow control of high flow rates

Type 8742 Mass flow controller Mass flow meter for multichannel gas flow systems

Precise gas control in laboratories

Type 8741 Mass flow control Mass flow meter

Products and systems for laboratory media control and dosing applications

Type 8745 Mass flow controller Mass flow meter


/ Fast, precise and consistent dosing / Bürkert’s time-pressure dosing technology helps to speed up the dosing process and increase the efficiency of your analytical device. In addition, the design of the valve prevents uncontrolled heat input into the medium and helps you achieve accurate test results. Good to know: We adapt Bürkert system solutions to your requirements – or develop an individual solution together with you.


Type 6650

Type 6712

Gas/Air

Type 6724

Regardless of the pressure used to dose a liquid, the valve opens and closes at the same speed, which can be seen using the example of a Type 6650 below. This allows you to increase or decrease pressure levels as required and still have the confidence that your valve is consistently working fast and precise.

Dosing Medium

Flow in Îźl/s 0.5 bar

2250

0.7 bar

1800

0.9 bar 1.1 bar

1350 We coordinate the valve and pump as well as the length and diameter of the supply lines, thereby ensuring the valve always switches exactly and in a consistent manner – even after routine replacement of the valve.

1.2 bar 1.3 bar

900 450 0

Time in Mins 0

15

30

45

60

BĂźrkert expertise

Type 8763 High precision pressure controller

Customer references

Dosing valves

Applications

Dosing

Diaphram pump


/ Precise gas control / With mass flow controllers (MFCs) by BĂźrkert, the fermentation process is reproducible. With their help, you can adjust the flow rate automatically and repeatably. The devices conform to USP Class VI, FDA and can be supplied with acceptance test certificate 3.1. In contrast to the measurement with variable area flowmeters using needle valves, they guarantee high quality and identical processes. Thanks to the high turn-down ratio, you can control very small to large gas flow rates with extreme precision.


Gas exhaust

MFC

Sampling Product harvest

MFC

Flow Control

Measurement points • ORP • Temperature • pH • Pressure • pO2

Conventional solution Rotameters are mechanical devices that measure the flow rate of a fluid in a closed tube. However, the principle used is based neither on mass-flow nor volume-flow measurement. They must be precisely calibrated and only function at the pressure and temperature for which they have been set.

Approval To ensure the quality of the final product, the components used must conform to the applicable approvals.

Bürkert expertise

MFC

Gas Supply

Customer references

MFC

Applications

Inoculation (if required)

Reproducible fermentation processes

Nutrient Solution



dosing units - BioSystems S.A. relies on Bürkert´s know-how and quality products.

Innovative ideas flow into a customised solution For precise and reliable measurement, regulation and control of the flow rates in the new dosing unit, BioSystems took advantage of the entire experience of the Bürkert Systemhaus. Both companies have high core competences in their respective fields. But it was the combination of their specific competences that allowed them to implement a unique and innovative solution for this high-level dosing application. A very important aspect for the Spanish engineers was Bürkert’s willingness to listen carefully and to respond by developing a solution in accordance with the exact requirements of BioSystems. Bürkert offered both an extensive spectrum of standard products and corresponding experience in the design of system solutions, which made Bürkert a clear choice as suitable partner for BioSystems.

The new development is based on Type 0127 (2/2- or 3/2-way solenoid valve) and the directacting media separated 3/2-way Twin Power rocker solenoid valve Type 6628 from Bürkert. Both valves feature rocker technology, which ensures not only a complete back pressure tightness, good flushability and a low internal volume, but also precise switching of micro volumes with minimal temperature rise through the coil. Due to complete fluid separation, these valves can be used for aggressive media. But the fluid specialist supplied more than just the solution for the control of fluid flows. An essential function in blood analysis is the detection and prevention of air bubbles, which can substantially corrupt the results of the analysis. Bürkert therefore avoided rough surfaces, dead zones and sharp edges in the design of the dosing unit. A special challenge

was the customer’s requirement for a transparent window for visual inspection, to be placed in front of the dosing unit and beneath the structure with the valves and pressure sensor. Bürkert developed an injection moulded part with a very high surface quality and no sharp edges in the area of the dosing unit. In each stage of the project Bürkert contributed its comprehensive experience with a high degree of commitment to find the decisive solution. Despite the new challenges and difficulties normally occurring with innovative developments, the two partners succeeded together in working out a forward-looking solution. The new one-for-all dosing unit can now be used in more than one analysis device. Large quantities mean lower manufacturing costs, so that in the end both partners benefit from the solution that was found.

Bürkert expertise

and flexible fluid analysis systems by modular designed and universally applicable

Customer references

/ Dosing unit leads to cost savings in clinical diagnostics / Cost efficient



is a Munich-based medical device manufacturer that develops and sells innovative CPAP systems for newborns and premature infants treated in intensive care units.

The latest product development – medinCNT® – works without a compressor thanks to the built-in turbine. Since it only needs to be connected to an oxygen cylinder instead of a central gas supply, this independently-operating, compact device is transport friendly and thus ideal for mobile use. medin® has been working closely with Bürkert for many years. The result of this collaboration provides young patients with the best possible support for a good start in life. Independently operating mobile systems are becoming increasingly popular in delivery rooms, ambulances and intensive care units. To address and tackle the considerable technical challenges, such as the precise recording and control of required gas volumes, medin® turned to the experts at Bürkert. The result of this joint development project is medinCNT®.

The latest generation of Bürkert proportional valves offers frictionless operation, combined with fast response times, highly dynamic performance and high repeat accuracy of ± 0.25%. This ensures significantly less deviation from the set value in the gas mixture flow rate than the ΔQ ≤± 2% at 20 litres per minute currently demanded by law. The Bürkert solution therefore guarantees ideal therapy solutions delivered in the most efficient way to young patients, making sure their lungs receive the best possible support for a good start in life. “The well-balanced unit, consisting of Bürkert valves, sensors and electronics along with the corresponding software, controls the oxygen concentration and the desired flow rate effectively and efficiently.” – Paul Schmitgen, technical and marketing manager at medin Medical Innovations GmbH

Bürkert expertise

save lives / Medical Innovations GmbH – or medin® in short –

Customer references

/ From the first breath, Bürkert technology is helping to


If you’re looking to develop bespoke solutions incorporating the highest level of creativity whilst being as economically conscious as possible, Bürkert offer you a place that promotes interdisciplinary and technologically autonomous work from the first idea all the way to production. In being part of the global picture, Bürkert’s experienced and trustworthy system developers all over the world are happy to assist in projects whenever required. Our highly qualified, motivated engineers and our outstanding production facilities are offered to Bürkert customers when required to tailor meet your needs. Bürkert Australia understand local, but think global. We embrace challenges and are constantly thinking future forward with product and system development, and all of this is at your disposal as one of our valued customers. Find out more about the added values that our Systemhaus offers you. • Avoiding unnecessary information losses and saving valuable time, thanks to interdisciplinary cooperation between Bürkert experts • True originality for the perfect technical solution, thanks to wide-ranging industry and application Expertise • Remarkable time and cost savings, with the help of industry-specific technology platforms

/ Bürkert Systemhaus – where your ideas feel at home / Working in partnership with you, we develop individual solutions that precisely meet your expectations.


Bürkert expertise

/ Local pacific teams / Since 1980, Bürkert has shown its commitment to bringing the highest level of quality and service to Australia and New Zealand.

Bürkert maintains a highly trained staff that is on hand to answer technical needs - from one-off basic solenoid valves, to comprehensive networked systems. Bürkert Australia HQ is located in Sydney, with large branch offices in all states, including some regional centres.

CABLE DUCT 40W x 100H

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CABLE DUCT 40W x 100H

M16

Wherever you are, Bürkert will be there to ensure you get the very best technical solution.

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Bürkert in New Zealand has its headquarters in Auckland and maintains presence throughout both the North and South Islands, serving Trans-Tasman customers.

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CABLE DUCT 40W x 100H

We make ideas flow.

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BĂźrkert Fluid Control Systems 15 Columbia Way Norwest Business Park Norwest NSW 2153 Australia Phone 1300 888 686 Fax 1300 888 076 sales.au@burkert.com www.burkert.com.au


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