Position for Molecular Diagnostics Growth: Millennium Helix

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Laboratory

Position for molecular diagnostics growth Millennium Helix Leading industry sources project that molecular diagnostics testing will grow 20 percent annually. And rapid advances are bringing about a revolutionary understanding of molecular mechanisms of disease and inspiring the discovery of breakthrough healthcare offerings. Is your lab properly positioned to take advantage of this new medical frontier? Millennium Helix™ for Laboratory places clinicians on the cutting edge of diagnostic medicine by simplifying the complexity of molecular data capture and providing clinicians with immediate access to genetic information. Built on the unified Cerner Millennium® architecture, Millennium Helix functions seamlessly with the PathNet® laboratory information system. This allows you to incorporate molecular diagnostic data into PathNet, in turn placing this important genomic data in your electronic health record (EHR). Millennium Helix adapts to your molecular diagnostic laboratory’s unique workflow and complex data-capture needs. The solution supports your documentation of

At a Glance mutation results, DNA methylation results, numeric results associated with short tandem repeat (STR) markers and viral loads, and engraftment analysis observations. The Unified Case Manager™ (UCM) is a central workspace for workflow management that allows you to clearly view the succession of activities within cases. The UCM seamlessly unites all applications you need to document a case—those specific to molecular diagnostics as well as many other existing PathNet capabilities. As a result, you can reduce procedural redundancy, control workflow and access information more quickly.

Optimise protocol and sample management Millennium Helix Protocol Management enables you to automatically document discrete data from common procedures to store online for easy retrieval. You can effortlessly capture data related to PCR (cycle conditions or number of cycles), reverse transcription, DNA isolation (260/280 ratios, purity), sequencing, gel loading and lot numbers from reagents. Protocol Management allows you to:

Millennium Helix provides you with: 

Inclusion of genomic data within the EHR

A central workspace for workflow management

Protocol and sample management optimisation

Data structure to promote translational medicine

Document protocols for multiple orders using batches

Customise content and appearance of protocols, as well as define default values and validation for the various captured data elements

Define and perform custom calculations

Ensure your team follows proper procedures in completing a protocol for each container

Automatically create sample

Cerner Limited / 6th Floor, The Point / 37 North Wharf Road / London W2 1AF / United Kingdom / Tel: +44 (0) 20 7432 8100 / www.cerner.co.uk / cerneruk@cerner.co.uk


containers through the protocol documentation

(For more information, visit https:// www.clinbioinformatics.org.)

Use Flat Files to efficiently transfer data between Cerner Millennium and other devices

In Millennium Helix™, using the CBO simplifies your database-building processes, supports cross-person comparison of genetic findings and enables advanced result-entry modes. The CBO also offers contextual information, creates prestandardised results and establishes a framework for sophisticated queries that reflect biological organisation. Results stored in Millenium Helix with a CBO concept identifier provide you with:

The Millennium Helix solution’s Sample Management feature allows you to easily track sample storage and create multiple generations of samples (such as DNA and PCR products) from a specimen. The seamless unification of protocol and sample management with patient cases provides additional

Key Benefits 

Improve molecular diagnostics data access, results standardisation and storage

Maximise processing efficiency through proper data correlation, case management, protocol and specimen management

Use a structured vocabulary to describe molecular diagnostic and cytogenetic concepts. quality assurance benefits, such as the ability to quickly retrieve all cases and samples affected by a reagent recall.

Embed bioinformatics standards Inherent in Millennium Helix is the ability to associate results with standardised coded values from the Clinical Bioinformatics Ontology™ (CBO). The CBO bridges the gap in existing medical and research vocabularies. As a result, you can use a structured vocabulary to describe molecular diagnostic and cytogenetic results discretely. The CBO is a curated resource. Experts in clinical genetics, molecular biology and informatics create and review each concept to ensure consistency and quality. These experts regularly review the practices, policies and scientific methodology applied to CBO management and maintenance.

A basis for standardised decision support templates in pharmacogenomics

Significant opportunities in data warehousing

A common foundation for the unified Cerner Millennium architecture to offer genomicsbased capabilities

Additional support for translational medicine

CBO is a component of the Cerner Controlled Medical Terminology™, which is a core decision support infrastructure layer in PathNet and other Cerner solutions.

cytogenetics result entry and reporting. In addition, Cerner is developing enhancements to extend support to the complex analysis process and capture of karyotype and fluorescence in situ hybridisation (FISH) images critical to results reporting.

Share accurate information As a Cerner Millennium solution, Millennium Helix helps health professionals drive safety, quality and efficiency. Clinicians connected to the centralised Cerner Millennium electronic medical record access vital information for effective decisionmaking. Sharing information from a common record helps you ensure accuracy and reduce the potential for errors. And in choosing Cerner solutions, you will work with an active partner that has more than 25 years of experience in laboratory information technology. For more information, please contact the Cerner team at +44 (0) 20 7432 8100 or visit our Web site at www.cerner.co.uk.

Unified Care Together with other Cerner laboratory solutions, Millennium Helix allows you to integrate and access comprehensive clinical data for accurate, timely decision making.

Support cytogenetics Millennium Helix supports many of the discrete results and task management processes associated with cytogenetics. Future developments will include modules specific to the unique needs of

Cerner Limited / 6th Floor, The Point / 37 North Wharf Road / London W2 1AF / United Kingdom / Tel: +44 (0) 20 7432 8100 / www.cerner.co.uk / cerneruk@cerner.co.uk UK_fl01_022_12_v1


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