CHeBA Annual Report 2020

Page 14

Epidemiology The Epidemiology Group is interested in studying the patterns, causes, risks, protective factors and effects of neurocognitive disorders, in particular dementia, in older populations in Australia and internationally. The group analyses longitudinal cohorts from CHeBA’s own studies – the Sydney Memory and Ageing Study, the Older Australian Twins Study, the Sydney Centenarian Study and the Sydney Stroke Study – as well as from international studies grouped into consortia, including the CHeBA-led COSMIC, STROKOG and ICC-Dementia. Another important aspect of this work is genetic epidemiology, which uses various approaches including genome-wide association studies and Mendelian randomisation methods to examine risk factors for dementia and other neurocognitive disorders. Group Leaders: Professor Perminder Sachdev, Professor Henry Brodaty Staff: Emeritus Professor Gavin Andrews, Dr Nicole Kochan, Dr Karen Mather, Dr John Crawford, Dr Anbu Thalamuthu, Dr Darren Lipnicki, Dr Yvonne Leung, Dr Vibeke Catts, Dr Ben Lam, Dr Louise Mewton, Dr Katya Numbers, Dr Catherine Browning, Jess Lo, Suzi Artiss

Professor Henry Brodaty, Dr Ben Lam, Dr Vibeke Catts, Dr Nicole Kochan, Dr Katya Numbers, Dr Karen Mather, Jess Lo, Dr Louise Mewton, Dr Anbu Thalamuthu, Professor Perminder Sachdev

Proteomics The Proteomics Group is a collaborative group composed of staff and students from CHeBA, the Neuropsychiatric Institute (NPI) and the MW Analytical Centre Bioanalytical Mass Spectrometry Facility (BMSF) at UNSW. The group was formed to apply state-of-the-art analytical techniques to the advancement of biomarker and pathophysiology research in the areas of normal ageing, mild cognitive impairment (MCI), Alzheimer’s disease and other age-related neurodegenerative conditions. While proteomics is a major focus area, the group utilises a broad spectrum of technologies and scientific approaches, including NMR, electron microscopy, confocal and fluorescence microscopy, FTIR spectroscopic imaging, LA-ICPMS mass spectrometric imaging as well as lipidomics and metabolomics techniques. Group Leader: Dr Anne Poljak Staff: Dr Tharusha Jayasena, Scientia Professor Perminder Sachdev, Maboobeh Hossieni, Dr Fei Song PhD Students: Gurjeet Virk (Scientia PhD candidate), Fatemeh Khorshidi (UPA PhD candidate), Rene Jezewski (Scientia PhD candidate), Toyin Abdulsalam (Scientia PhD candidate), Dr Matthew Wong (BSc Hons, PhD)

Gurjeet Virk, Maboobeh Hossieni, Matthew Wong, Rene Jezewski, Dr Anne Poljak, Fatemeh Khorshidi, Professor Perminder Sachdev, Rhiagh Cleary, Dr Fei Song, Toyin Abdulsalam, Dr Tharusha Jayasena

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Appendix H: Conference Presentations

13min
pages 104-105

Appendix G: Publications

49min
pages 98-103

Appendix C: Postgraduate Students

6min
pages 90-91

Current Projects

1hr
pages 54-83

Appendix B: External Appointments

9min
pages 87-89

Completed Projects

1min
pages 84-85

CHeBA Collaborators

6min
pages 50-53

Public Forums

2min
pages 45-46

Major Supporters

3min
pages 47-49

CHeBA Visiting Lecture Series

1min
page 44

CHeBA in the Media

1min
page 43

The Brain Dialogues

2min
page 42

CHeBA Publication Awards

4min
pages 37-39

InThisTogether

1min
pages 40-41

Sydney Memory & Ageing Study

6min
pages 30-31

PhD Research Features

5min
pages 34-36

Maintain Your Brain

2min
page 32

Older Australian Twins Study

2min
page 29

Sydney Centenarian Study

3min
page 28

SHARED

1min
pages 26-27

COSMIC

4min
pages 22-23

STROKOG

4min
pages 24-25

Neuropsychology

2min
pages 18-19

COGNISANCE

5min
pages 20-21

Neuropsychiatry

1min
page 17

Neuroimaging

2min
page 16

Genetics & Epigenomics

3min
pages 14-15

Brain Ageing Research Laboratory

2min
page 13

Research Grant to Fund Major Advance in Fight Against Dementia

2min
page 6

Effects of Alcohol Greatest in Three Key Periods

1min
pages 10-11

Co-Directors' Report

4min
pages 2-3

Metformin Treatment Linked to Slowed Cognitive Decline

1min
page 9

People Aged 95+ Show Greater Brain Connectivity

1min
page 7

Certain Memory Complaints Predict Future Dementia

1min
page 8

About the Centre

2min
pages 4-5
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