Immune Tolerance Induction (ITI/ITT - a treatment to eradicate inhibitors, or halt the body's tendency to reject factor replacement) began in the 80's with little change to its methods today. Dr. Robert Sidonio, Jr. (Emory University - Atlanta) is looking to change that as co-investigator of the MOTIVATE trial, which seeks out improved regimens by including study groups on the available medications including factor, non-factor, and bypassing agents.
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