One & Two Discovery Square

One & Two

One Discovery Square: A Healthcare

HEALTHCARE INNOVATION

CAMPUS

Encounter the epicenter of healthcare innovation in Rochester, Minnesota: America’s City for Health. The 16-block Discovery Square District is one of the key components in the Destination Medical Center ’s (DMC) $6 billion investment in Rochester, the largest public-private partnership in state history. Since 2013, the DMC has worked to support the city of Rochester and Mayo Clinic as a global destination on the leading edge of healthcare research and implementation.

At the heart of the district is the One Discovery Square Healthcare Innovation Campus, a hub for healthcare innovation made up of One Discovery Square and Two Discovery Square. These buildings, outfitted with innovative design and technology, encourage a team approach to tackling crucial challenges in healthcare. At One Discovery Square Campus, scientists, physicians, researchers and educators come together to turn discovery into action, allowing for ideas to go from bench to bedside faster. Located just steps away from more than 1.5 million square feet of research and lab space and adjacent to the future Discovery Walk, One Discovery Square offers:

ACCESS X MAYO CLINIC

> An unparalleled partnership with the nation’s leading medical organization

CULTURE X PLACE

> An unrivaled space for collaboration in a fully integrated live-work-play ecosystem

SPEED X MARKET

> An unprecedented acceleration of discoveries, translated for global demand

With Mayo Clinic at its core, One Discovery Square is THE ONLY collaborative model in which higher education, startups and Mayo Clinic’s partner companies can work together in the same space. Specially built to support healthcare innovation, the campus features:

> Specialized event programming by the Musicant Group

> Wired scored buildings with backup generators

> Infrastructure for wet and dry labs, GMP, simulation facilities and specialized equipment

> Office and training space

> Common area amenities:

— Breakout areas

— Multiple conference rooms

— Onsite cafe

— Collaboration hall

— Multiple outdoor courtyards

— Bike lockers

“This is an exciting project for Rochester. The Destination Medical Center and its sub-districts will stand as an example for the city of the future—a re-imagined home for innovation. For the community, state of Minnesota and leaders in the life science industry, this major achievement will transcend the previously established limits of how we define dimensional access to health and wellness.”

- Andre Terzic, M.D., Ph.D., Director, Center

for Regenerative Medicine, Mayo Clinic

Healthcare Innovation Campus

ACCESS X MAYO CLINIC

As a business operating in One Discovery Square, you will have meetings with Mayo Clinic Ventures staff for routine reviews of new intellectual property. The collaboration can extend to opportunities for evaluation and co-development of new and existing technologies with input from distinguished clinicians and scientists.

One Discovery Square businesses have a strategic workforce advantage. Mayo Clinic College of Medicine and Science offers cutting edge programs in biomedical research, medical and clinical education. World-class faculty have the ability to tailor innovative training and curriculum to meet companies’ evolving staffing needs.

Tenants at One Discovery Square will have access to many of Mayo Clinic’s Core services including:

Genome Analysis Core

> Genome, Exome and Transcriptome Sequencing

> Genotyping

> Gene Expression

BAP

> Nucleic Acid Extraction

> Plasma/Serum Separation

Immunochemical Core Lab

> Mass Spec, Cobas, Elisa and RIA Platforms for Small Molecule Analysis and Other Analytes

Metabolomics Core

> Mass Spectrometers, Liquid and Gas Chromatography Platforms to Identify and Analyze

Metabolites

Microscopy and Cell Analysis Core

> Electron Microscopy

> Light Microscopy

> Flow Cytometry

Pathology Research Core

> Sectioning Both Paraffin-Embedded and Frozen Tissues

> Automated Staining for Immunohistochemistry, Immunofluorescence and RNA in Situhybridization

> Tissue Microarray Construction with 60 to 360 Cores

> Digital Analysis of Whole Tissue and TMA Slides

Fostering a Culture

CULTURE X PLACE

One Discovery Square is laser-focused on fostering a culture of collaboration between tenants and the outside business, research and Rochester communities. Our professionally programmed common areas have become epicenters for cross-sector meetings, brainstorming sessions, lunch-and-learns from industry leaders, creative “left brain” programming, networking events and your next big breakthrough. Our programmed spaces generate structured serendipity where collaboration is in the air and working together is the norm.

At One Discovery Square, you’ll find:

> 10-15 events a week that bring the Mayo Clinic, business, research and Rochester communities to your doorstep

> Onsite event planning services to help your company plan their next event, from team lunches to product launches

> Multiple conference and breakout rooms throughout the building to support any size of meeting

> The best coffee in Rochester at on-site Cafe Steam

> Flexible training and conference center for up to 125 people

> Multiple common areas with shared courtyard

Examples of Events:

> Biweekly TGIM (Thank God It’s Monday) free breakfast gatherings for tenants

> Monthly happy hours that are quickly becoming the “must-attend” event in Rochester

> Wellness Wednesdays — a rotating array of yoga, massage, meditation and more

> LeaderSHARE — a quarterly gathering with leaders from each tenant

> Weekly Left Brain programming focused on creativity in partnership with UMR

> Food Truck Fridays

> 1 Million Cups entrepreneurship gathering every month

> Taco Bout Innovation lunch-and-learns

> Lunch with Ted — monthly TED talk lunches

Culture of Collaboration

SPEED X MARKET

The rich Medical Alley ecosystem within Minnesota speeds the development while shortening the time to market of life-saving and life-improving health care innovation.

At One Discovery Square, What’s Here is What’s Next:

> Next to the #1 hospital in the United States, Mayo Clinic

> Next to the largest health insurance company in the United States, UnitedHealth Group

> Next to the largest device company in the world, Medtronic

> Next to a globally-ranked research university, the University of Minnesota

> Next to thousands of specialized suppliers, consultants, advisers and more that make up the half a million people who work in health and medical innovation in Minnesota

Information provided by:

Frank Juskulke | Vice President of Intelligence, Medical Alley Association

One Discovery Square

CURRENT TENANTS

4th Floor

Mayo Clinic - Regenerative Medicine

RION

3rd Floor

Mayo Clinic - Advanced Diagnostics & Regenerative Medicine

University of Minnesota Rochester - Classrooms & Lab

2nd Floor

Mayo Clinic - Ultrasound Imagery & Artificial Intelligence aiforia

Philips

Exact Sciences

Sersense

Motion Medical by Boston Scientific

1st Floor

Epic

University of Minnesota Rochester

What’s Here

ONE DISCOVERY SQUARE

One Discovery Square is an 81,000 square foot state-of-the-art life science building designed to foster collaboration and innovation. It is professionally programmed to create a culture of collaboration with building amenities that are strategically designed to foster an interactive culture and generate structured serendipity with an advanced healthcare innovation ecosystem. One Discovery Square is a building that fosters knowledge. It is a place where collaboration is key and working together is the norm.

Building amenities include:

> Professionally Programmed Building

> Collaborative Team Spaces

> Multiple Shared Conference Rooms Per Floor

> On-Site Cafe

> Multiple Common Areas with Shared Courtyard

> Infrastructure for Wet, Dry Labs, GMP Facilities

> Access to Retail, Restaurants, Hotels & Services

Two Discovery Square

NEW CAMPUS AMENITIES

> Flexible training & conference center for over 100 people

> Collaborative breakout spaces

> Additional building conference rooms

> Private outdoor patios

> Connected campus via glass atrium

> Bike storage

FLEXIBLE LAB CAPACITY

> Infrastructure for Wet, Dry Labs, GMP facilities

> VC-A 2000 vibration mitigation

> Up to 16 feet ceiling height for specialized equipment

> Structural reinforcement for imaging, 3D printing and specialty equipment

> Oversized mechanical chases for specialty HAC and gases

> On-site generator

WIRED SCORED BUILDING WITH LEADING EDGE TECHNOLOGY

> Building designed for digital diagnostics & analysis

> Capacity for simulation & learning labs

> Wired scored building—only 8 buildings in Minnesota with certification, Discovery Square 2 will be the first in Rochester

> Providing digital infrastructure

> Working with service providers in anticipation of 5G connectivity

What’s Ne t

TWO DISCOVERY SQUARE

Two Discovery Square is a 125,000 square foot wired scored, state-of-the-art building with leading edge technology. Only eight buildings in Minnesota with Wired Scored Certification exist; Two Discovery Square will be the first of its kind in Rochester. The iconic architecture, exceptional amenities and cutting edge design of Two Discovery Square attract unique tenants seeking the ultimate in collaboration, innovation and technology.

Discovery Square: The

Epicenter of Innovation

SITE X LOCATION

STEPS AWAY FROM OVER 1.5 MILLION SQUARE FEET OF THE WORLD’S LEADING RESEARCH AND CLINICAL LABS

Known first and foremost as the home to Mayo Clinic, Rochester, Minnesota is one of the most educated cities in t he world and home to some of the best and brightest minds in the medical industry. Providing the setting for “America’s City for Health,” Rochester is a city bustling with local culture and cuisine, community involvement, education and the arts.

Rochester is the gateway for partner companies looking to expand and collaborate with the world’s leading healthcare providers and innovators. The Discovery Square campus sits at the heart of the Discovery Square district as the central meeting hub for researchers, physicians, entrepreneurs, leaders and students.

Two Discovery Square