Biomedical Sciences

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Table of Contents Biomedical Engineering Biochemistry ...................................................................................................................................................................3 Biomaterials & Medical Devices........................................................................................................................................8 Biomedical Engineering..................................................................................................................................................13 Biomedical Imaging........................................................................................................................................................30 Methods & Instrumentation...........................................................................................................................................37 Nanobiotechnology.......................................................................................................................................................41 Immunology..................................................................................................................................................................45 Biomedical Science Cell Biology....................................................................................................................................................................45 Lab Animal Science........................................................................................................................................................47 Microbiology..................................................................................................................................................................51 Molecular Biology..........................................................................................................................................................52 Neuroscience.................................................................................................................................................................53 Toxicology......................................................................................................................................................................58 Pharmaceutical Science Biopharmaceuticals........................................................................................................................................................58 Clinical Trials..................................................................................................................................................................59 Drug Discovery & Development.....................................................................................................................................60 Management.................................................................................................................................................................63 Pharmaceutical Science..................................................................................................................................................64 Pharmacology................................................................................................................................................................64 Pharmacy.......................................................................................................................................................................67 Regulation, Standards, & Validation................................................................................................................................68 Mathematics & Statistics for Biomedicine Bioinformatics................................................................................................................................................................68 Biostatistics.....................................................................................................................................................................70 Mathematics for Biology & Medicine..............................................................................................................................81 Statistics for Biological Science.......................................................................................................................................83 Statstical Theory & Methods..........................................................................................................................................84 General References.........................................................................................................................................................91 Title Index.............................................................................................................................................................................92 Author Index.........................................................................................................................................................................96 Sales Agents........................................................................................................................................................................103

Biomedical Sciences

Biotechnology................................................................................................................................................................32


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Textbook

Advanced Practical Organic Chemistry Third Edition John Leonard

Applications of Supramolecular Chemistry Edited by

AstraZeneca, Macclesfield, Chesire, UK

Hans-Jörg Schneider

Barry Lygo

Universitat des Saarlandes, Saarbrucken, Germany

Garry Procter Harvard University, Massachusetts, USA

With an emphasis on the most up-to-date techniques commonly used in organic synthesis, this third edition reference draws on the extensive experience of the authors and their association with some of the world’s leading laboratories of synthetic organic chemistry. Written mainly for postgraduate, advanced undergraduate, and industrial organic chemists, this book emphasizes understanding rather than learning facts and offers fully updated information and re-drawn figures to illustrate the information at the highest possible standard. The increased size of the book, to 7 by 10 inches, makes it more user friendly and allows space for notes in the sidebars. Figure slides are available upon qualifying course adoption. Catalog no. K12806, ISBN: 978-1-4398-6097-7 January 2013, 6-1/8 x 9-1/4, 362 pp., Soft Cover Suggested Price: $69.95 / £44.99 Also available as an eBook

Covering the most important supramolecular technologies within a single volume, this book provides a comprehensive introduction for both newcomers to the field and for specialists who are looking for new applications. Internationally recognized specialists in the different fields describe in detail the most promising but already established techniques, including biotechnology, decontamination, environmental control, biomedical analyses/monitoring, supramolecular electronics, and intelligent materials. The text offers a complete overview of important applications in supramolecular chemistry, which hold particular promise for future developments.

Biochemistry

University of Nottingham, UK

Catalog no. K11858, ISBN: 978-1-4398-4014-6 March 2012, 6-1/8 x 9-1/4, 453 pp. Suggested Price: $99.95 / £63.99

Bioactive Natural Products Detection, Isolation, and Structural Determination, Second Edition Edited by

Steven M. Colegate CSIRO/Plant Toxins Unit, Division of Animal Health, Geelong, Australia

Amino Acid Chelation in Human and Animal Nutrition H. DeWayne Ashmead Albion Laboratories, Clearfield, Utah, USA

An examination of the increased bioavailability of amino acid chelates, this book assembles chemical, clinical, and nutritional studies explaining how the body responds to amino acid chelates. It presents analytical procedures for producing amino acid chelates that are used in research relating to mineral bioavailability. The chapters cover fundamentals of mineral nutrition, the chemistry of chelation, the history of nutritional chelates, absorption pathways, tissue metabolism and metabolic responses, nutrient uptake, and toxicity of amino acid chelates. Catalog no. K14289, ISBN: 978-1-4398-9767-6 February 2012, 6-1/8 x 9-1/4, 269 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Russell J. Molyneux Western Regional Research Center, Albany, California, USA

Following the successful format of the original, this new edition presents applications of the most recent techniques for the detection, isolation, and structural determination of bioactive natural products. It features new case studies and illustrations that demonstrate applications of techniques covered in the book. Complementing as much as replacing the first edition, most of the contributors are new. The text includes updates on chemical extraction, and NMRbased structure determination, and new contributions on liquid chromatography linked with mass and NMR spectroscopy, dereplication approaches, assessment of source material for natural products, and novel bioassay development. Catalog no. 7258, ISBN: 978-0-8493-7258-2 December 2007, 7 x 10, 624 pp. Suggested Price: $249.95 / £159.00 Also available as an eBook

Biomaterials Science An Integrated Clinical and Engineering Approach

Amino Acids

Edited by

Biochemistry and Nutrition

Superior NanoBioSystems, Silver Spring, Maryland, USA

Yitzhak Rosen Noel Elman

Guoyao Wu Texas A & M University, College Station, USA

This up-to-date book presents basic concepts and recent advances in amino acid biochemistry and nutrition, providing comprehensive coverage of developments over the past 45 years. It includes information on absorption, metabolism, and excretion of amino acids while addressing protein quality and requirements. The text discusses metabolic pathways of amino acids in relation to health and disease in various organisms, as well as species differences in metabolism of amino acids. The author also presents a critical analysis of amino acid supplementation to humans and animals. Catalog no. K12865, ISBN: 978-1-4398-6189-9 April 2013, 6-1/8 x 9-1/4, 472 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Cambridge, Massachusetts, USA

Rather than approaching biomaterials science from just the materials science and engineering perspectives, this book also covers the clinical side. The goal is to engage biomaterials engineers and physicians in a much-needed discussion that integrates both fields at many levels. The objective is, therefore, to increase the rate of successful deployment of biomaterials, lower the side effects of such a deployment, and accumulate knowledge for improving current methodologies and meeting future challenges. Leading contributors address topics such as hemocompatibility, carcinogenesis, infections, and cellular mechanisms, as well as signal transduction, clinical trials, MEMS, nanotechnology, FDA regulations, and ethical issues. Catalog no. K10223, ISBN: 978-1-4398-0404-9 June 2012, 6-1/8 x 9-1/4, 310 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

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3


Biotechnology of Plasma Proteins Roger L. Lundblad

Edited by

Peter Grunwald

Biochemistry

Lundblad Biotechnology, Chapel Hill, North Carolina, USA

University of Hamburg, Germany

Discussing the role of plasma proteins in current biotechnology, this book describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, and mass spectrometry, as well as updates not published since 1975.

Carbohydrates have long been disregarded by the scientific community due to their complex structure and a lack of suitable experimental methods for structure determination. This book provides an overview of the structure, function, and application of carbohydrate-modifying biocatalysts. It explores glycoconjugates and carbohydrate-modifying enzymes and the key roles they play in biological processes such as recognition, signal transduction, and immune responses. It discusses research activities in glycoscience, including the development of several new pharmaceuticals to treat malaria, cancer, and other diseases.

Catalog no. K12286, ISBN: 978-1-4398-5026-8 August 2012, 6-1/8 x 9-1/4, 460 pp. Suggested Price: $149.95 / £95.00

Catalog no. N10454, ISBN: 978-981-4241-67-0 October 2011, 6 x 9, 846 pp. Suggested Price: $299.95 / £191.00

Also available as an eBook

Also available as an eBook

Carbohydrate Chemistry

Chemical Genomics and Proteomics

Proven Synthetic Methods, Volume One

Second Edition Edited by

Edited by

Ferenc Darvas and György Dormán

Pavol Kováˇc National Institutes of Health, Bethesda, Maryland, USA

4

Carbohydrate Modifying Biocatalysts

ThalesNano Nanotechnology Inc., Budapest, Hungary

Series: Carbohydrate Chemistry

András Guttman

Useful in the glycosciences, this book presents reliable protocols for the preparation of synthetic carbohydrates. Featuring worldwide contributors and a well-known series editor, the text presents new or older, not easy to find protocols generally useful to those interested in synthetic carbohydrate chemistry. Having an independent checker verify the experimental portion of the text to ensure reproducibility, the Proven Synthetic Methods Series brings state of the art of synthetic carbohydrate chemistry at par with general organic synthesis. Methods presented include more detailed versions of protocols that have been previously published and some new methods for the synthesis of a variety of carbohydrate derivatives.

This interdisciplinary reference identifies and elucidates the most influential developments in chemical genomics for improved research and advancement in a diverse array of fields ranging from proteomics, bioinformatics, and microfluidics to drug discovery and toxicology. The book tracks the emergence of a large variety of novel techniques such as the small-molecule druggability of new targets, the generation and synthesis of small-molecule libraries, and the determination of targets and mechanisms by genomic profiling. It guides readers in the selection of the most appropriate technology for their specific dilemma by highlighting procedures utilized in other scientific disciplines.

Catalog no. K12999, ISBN: 978-1-4398-6689-4 September 2011, 6-1/8 x 9-1/4, 468 pp. Suggested Price: $157.95 / £101.00

Catalog no. K11499, ISBN: 978-1-4398-3052-9 December 2012, 6-1/8 x 9-1/4, 240 pp. Suggested Price: $159.95 / £99.00

Also available as an eBook

Horvath Laboratory for Bioseparation Sciences, Debrecen, Hungary

Also available as an eBook

Carbohydrate Chemistry Proven Synthetic Methods, Volume Two Edited by

The Chemistry Companion

Gijsbert van der Marel and Jeroen Codee

A. C. Fischer-Cripps

Leiden University, The Netherlands

Fischer-Cripps Laboratories Pty Ltd, Sydney, Australia

Series: Carbohydrate Chemistry

This second edition of a bestseller is a compilation of reliable protocols for the preparation of intermediates for carbohydrate synthesis or other substances and methods performed at the bench, which can be expected to be useful in the glycosciences. Written for graduate students and researchers in carbohydrate chemistry, biochemistry, medical chemistry, and glycobiology, this book explores carbohydrate chemistry from both academic and industrial points of views, offering contributions from world-renowned experts. It includes figures with the text, to aid with reader comprehension.

Like the author’s other companion books, The Chemistry Companion provides high-quality information in unique one-page-per-topic presentations that do not overburden and distract readers with excessive details. Suitable as an introduction or study guide, the book offers concise summaries of general chemistry concepts, easily accessible in a convenient, reader-friendly format. It presents the minimum of what readers need to know to understand the subject. Emphasizing the physics underlying chemistry, the book enables readers to better appreciate what is happening from the chemical perspective that is usually found in traditional chemistry books.

Catalog no. K13528, ISBN: 978-1-4398-7594-0 May 2013, 6 x 9, 500 pp. Suggested Price: $149.95 / £95.00

Catalog no. K11517, ISBN: 978-1-4398-3088-8 August 2011, 5-1/2 x 8-1/2, 195 pp., Soft Cover Suggested Price: $31.95 / £19.99

Also available as an eBook

Also available as an eBook

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CRC Handbook of Organic Photochemistry and Photobiology Chemistry of Heterocyclic Compounds

Third Edition - Two Volume Set

Rakesh Kumar Parashar

Michael Oelgemöller

This book discusses the structure, synthesis, and reactivity of heterocyclic compounds. It covers nomenclature, conformational aspects, aromatic stabilization, and biological activity of heterocyclic compounds. The book also includes discussions of biochemical processes involving destruction of heterocyclic rings. It includes problem sets that help readers to understand and apply the principles of heterocyclic reactivity and synthesis. The inclusion of more advanced material and references make the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry, particularly in the pharmaceutical and agrochemical industries. Catalog no. K15092, ISBN: 978-1-4665-1713-4 August 2012, 6-1/8 x 9-1/4 Suggested Price: $89.95 / £57.99

Chirality in Biological Nanospaces Reactions in Active Sites

University of Cologne, Germany James Cook University, Townsville, Queensland, Australia

Francesco Ghetti CNR Istituto Biofisica, Pisa, Italy

With a new editorship and expanded contents, the third edition of this bestselling handbook continues to provide an authoritative and unique resource for those working and studying in the areas of photochemistry and photobiology. Leading experts offer enlightening contributions on traditional topics, current trends, and future directions. New and updated topics in this edition include industrial and microphotochemistry, photoimmunology, artificial photosynthetic systems, phototoxicity of drugs, and much more.

Biochemistry

University of Delhi, India

Axel Griesbeck

Catalog no. K14351, ISBN: 978-1-4398-9933-5 March 2012, 7 x 10, 1694 pp. Suggested Price: $479.00 / £305.00 Also available as an eBook

Development of Medical Garments and Apparel for the Elderly and the Disabled Ng Sau-Fun, Hui Chi-Leung, and Wong Lai-Fan Series: Textile Progress

Nilashis Nandi University of Kalyani, India

Activity in the nanodimensional active sites of large biological macromolecules greatly accelerates biological reactions. The chirality of the reactants also has a strong influence on the process, but its importance in such biological reactions has only recently begun to be understood. This book explores the influence of chirality on reaction mechanisms in such biological nanospaces. The text addresses ribosomal architecture and the influence of the chirality of amino acid and sugar in the active sites of transferase, oxidoreductases, hydrolases, lysases, isomerase, ligases, and other systems. Catalog no. K11852, ISBN: 978-1-4398-4002-3 July 2011, 6-1/8 x 9-1/4, 209 pp. Suggested Price: $125.95 / £79.99 Also available as an eBook

Chitosan-Based Hydrogels

Although the main theme of this book is products for the elderly and the disabled, it also contains major sections on medical garments, which include personal protective equipment (PPE), hip protectors (HP), pressure garments (PG), compression stockings (CS), wet dressings, products for wound dressing, adult incontinence products, sanitary napkins, disposable diapers, vital signs monitoring garments, motion aware clothing, wearable sensors and smart diapers, and so on. The development of apparel for the elderly and the disabled is a challenge for the healthcare and clothing industries. The developed apparel products are not only based on various design, fashion, and comfort concepts but also considered in terms of particular medical problems, restorative care functions, and appropriate solutions for healthcare purposes. Catalog no. K14984, ISBN: 978-1-4665-1435-5 March 2012, 6 x 9, 56 pp., Soft Cover Suggested Price: $29.95 / £14.99

Emergent Patterns and the Brain Michael Thompson

Functions and Applications

University of Toronto, Ontario, Canada

Edited by

UCLA Crump Institute for Molecular Imaging, Los Angeles, California, USA

Saman Sadeghi

Kangde Yao, Junjie Li, Fanglian Yao, and Yuji Yin Tianjin University, People’s Republic of China

This work details the latest progress in the research and development of chitosanbased biomaterials, providing the foundation for future research. The book introduces the formation and chemical structure of chitosan-based hydrogels. It also discusses the relationship between their structure and functions, which provides a theoretical basis for the design of biomaterials. In addition, many realworld examples illustrate the potential application of chitosan-based hydrogels in various fields, including materials science, biotechnology, pharmaceuticals, regenerative medicine, and cell engineering.

Written by well-respected researchers, this book describes how the human brain can process sensory information through the generation of emergent patterns, exploring the processes that enable thoughts to arise. The text addresses such concepts as consciousness, the role of complexity in emergence, the intelligence of complex systems, the human brain as a system, spatio-temporal patterns in the brain, self-organization, and synthetic cognitive system design. The contributors also discuss what lies ahead for the future of designed complex systems. By integrating the interdisciplinary fields of neuroscience and neurology, the text presents a logical approach to this topic.

Catalog no. K11120, ISBN: 978-1-4398-2114-5 July 2011, 7 x 10, 521 pp. Suggested Price: $199.95 / £127.00

Catalog no. K11956, ISBN: 978-1-4398-4201-0 May 2013, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $139.95 / £89.00

Also available as an eBook

Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

5


Fluctuation Theory of Solutions Applications in Chemistry, Chemical Engineering, and Biophysics

Handbook of Biochemistry and Molecular Biology Fourth Edition

Edited by

Edited by

Paul E. Smith

Roger L. Lundblad

Kansas State University, Manhattan, USA

John P. O’ Connell University of Virginia, Charlottesville, USA

Enrico Matteoli National Research Council, Institute for Chemical Physical Processes, Italy

Biochemistry

Fluctuation theory is an important tool for the analysis and understanding of many aspects of chemistry, chemical engineering, and biophysics occurring in solutions. It is the most complete and accurate approach but is often underused and underappreciated. This book outlines the theory, provides a tutorial on how to calculate various properties from both experiment and simulation, and reviews applications covering a wide variety of areas of research. It summarizes the potential use of fluctuation theory in a variety of research. Catalog no. K14345, ISBN: 978-1-4398-9922-9 February 2013, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $129.95 / £82.00

Lundblad Biotechnology, Chapel Hill, North Carolina, USA

Fiona M. Macdonald CRC Press, Boca Raton, Florida, USA

Edited by renowned protein scientist and bestselling author Roger Lundblad, with the assistance of Fiona Macdonald of CRC Press, this volume represents a dramatic revision—the first in two decades—of one of biochemistry’s most referenced works. Presented in a simple-to-use format, this popular reference allows quick access to the most frequently used data on proteins, lipids, nucleic acids, and carbohydrates. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. Catalog no. 9168, ISBN: 978-0-8493-9168-2 May 2010, 8-1/2 x 11, 1098 pp. Suggested Price: $219.95 / £140.00 Also available as an eBook

Also available as an eBook

Fundamental QSARs for Metal Ions John D. Walker US EPA, Washington, DC, USA

Handbook of Lipid Bilayers

Michael C. Newman

Second Edition

College of William & Mary, Gloucester Point, Virginia, USA

M. Enache

6

Derek Marsh

University of Agricultural Sciences, Bucharest, Romania

Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany

Focusing on the niche field of metal ion toxicity in Quantitative Structure Activity Relationships (QSAR), this text concentrates on the basic and essential applications of QSAR methods in metal ions for readers already familiar with the field and statistics. It delineates the theoretical basis and provides a concrete introduction to studying the biological activity and toxicity of metal ions as they impact health and the environment. The book describes the applications of QSARs in characterizing the biological activity and toxicity of metal ions and provides parameters for the correlation of structure with inorganic biological activity. It includes a CD-ROM with approximately 100 references on QSARs for metal ions.

This handbook provides the only one-stop resource for primary physicochemical data relating to phospholipid bilayers. Coverage includes both dynamic and structural properties of phospholipid bilayers, along with basic thermodynamic data. With more than twice as much data, this second edition contains new sections on phase diagrams with cholesterol, hydration isotherms, spontaneous curvature, and cubic phases. It also presents much expanded information on glycolipids and includes more detailed introductory sections that explain important concepts and provide a broader framework for understanding the data.

Catalog no. 8433X, ISBN: 978-1-4200-8433-7 December 2012, 6-1/8 x 9-1/4, 296 pp. Suggested Price: $139.95 / £89.00

Catalog no. 88327, ISBN: 978-1-4200-8832-8 December 2012, 8-1/2 x 11, 1130 pp. Suggested Price: $249.95 / £159.00

Also available as an eBook

Also available as an eBook

Handbook of Aqueous Solubility Data Second Edition Samuel H. Yalkowsky University of Arizona, Tucson, USA

Yan He Sanofi-Aventis, Bridgewater, New Jersey, USA

Parijat Jain Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA

The second edition of this landmark volume continues the tradition of providing an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. It adds 2,000 new solubility values, bringing the total count to over 18,000 data points for more than 4,000 organic compounds. It includes data for pharmaceuticals, pollutants, nutrients, herbicides, pesticides, and agricultural, industrial, and energy-related compounds. Each compound is identified by a sequential number along with molecular formula, compound name, synonyms, molecular weight, CASR number, melting point, and boiling point if available. Catalog no. K10130, ISBN: 978-1-4398-0245-8 April 2010, 7 x 10, 1620 pp. Suggested Price: $441.00 / £281.00 Also available as an eBook

Hansen Solubility Parameters A User’s Handbook, Second Edition Charles M. Hansen Charles M. Hansen Consulting, Hoersholm, Denmark

In this new edition, Charles M. Hansen invites five renowned experts to share their innovative work on novel topics such as using statistical thermodynamics to confirm existing HSPs, reconciling HSP with other thermodynamic theories, predicting the behavior of carbon dioxide, environmental stress cracking, absorption and diffusion in polymers, and other insight on future applications in biological materials, controlled release, nanotechnology, and self-assembly. The book highlights recent findings on interactions with DNA, and other novel applications of HSPs, such as ozone-safe solvents, protective clothing, drug delivery systems, and petroleum applications. Catalog no. 7248, ISBN: 978-0-8493-7248-3 June 2007, 7 x 10, 544 pp. Suggested Price: $199.95 / £127.00 Also available as an eBook

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Textbook

An Introduction to Biomaterials Second Edition

Introduction to Proteins Structure, Function, and Motion Es-is Technologies Ltd., Givatayim, Israel

Jeffrey O. Hollinger

Nir Ben-Tal

Carnegie Mellon University, Pittsburgh, Pennsylvania, USA

Tel Aviv University, Israel

Series: Biomedical Engineering

Series: Chapman & Hall/CRC Mathematical & Computational Biology

The second edition of this popular text includes nine new chapters that provide a comprehensive and up-to-date educational framework for biomaterials education. A new chapter on the biology of wound healing sets the stage for the basic requirements of standardized biomaterials testing and explains the reactions between biomaterials and the living system into which it is implanted. The book explains in vitro and in vivo testing paradigms and provides numerous examples in the chapters on experimental design, laboratory assays, and animal models. Emphasizing the importance of the regulatory process, it describes how innovation in the biomaterials process relates to patentability and inventorship.

With more than 350 color images throughout, this text presents a unified, indepth treatment of the relationship between the structure, dynamics, and function of proteins. Taking a structural–biophysical approach, the authors discuss the molecular interactions and thermodynamic changes that transpire in these highly complex molecules. They use numerous proteins as examples to illustrate the topics and principles and to show how proteins can be analyzed in multiple ways. The text refers to many everyday applications of proteins and enzymes in medical disorders, drugs, toxins, chemical warfare, and animal behavior. Downloadable questions for each chapter are available at CRC Press Online.

An instructor’s manual and slides are available upon qualifying course adoption

A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. K10637, ISBN: 978-1-4398-1256-3 November 2011, 7 x 10, 644 pp. Suggested Price: $119.95 / £49.99

Catalog no. K10533, ISBN: 978-1-4398-1071-2 December 2010, 7 x 10, 654 pp. Suggested Price: $87.95 / £56.99

Also available as an eBook

Also available as an eBook

Biochemistry

Amit Kessel

Edited by

Textbook

Organic Chemistry Introduction to Lipidomics

An Acid-Base Approach

From Bacteria to Man

Michael B. Smith

Claude Leray

Most reactions in organic chemistry can be explained by variations of fundamental acid–base concepts. This volume provides a framework for understanding the subject that goes beyond mere memorization. Using several techniques to develop a relational understanding, this text helps students fully grasp the concepts at the root of organic chemistry. Chapters contain checklists of what students need to know before they begin to study a topic and concepts to be fully understood before moving to the next subject area, homework problems directly tied to each concept at the end of each chapter, embedded problems with answers throughout the material, and experimental details and mechanisms for key reactions.

University of Connecticut, Storrs, USA

The first comprehensive book on lipidomics, this long-awaited work inventories the huge variety of lipid molecules present in all aspects of life, detailing structures from animal, plant and bacterial cells, marine ecosystems, and littleknown structures from bibliographic data. A true text rather than just a catalog, it is highly informative and educational while simultaneously being anecdotal and interesting to read. Catalog no. K15167, ISBN: 978-1-4665-5146-6 September 2012, 6-1/8 x 9-1/4, 339 pp., Soft Cover Suggested Price: $99.95 / £63.99

A solutions manual is available upon qualifying course adoption

Catalog no. 79204, ISBN: 978-1-4200-7920-3 October 2010, 7 x 10, 1592 pp. Suggested Price: $152.95 / £97.00

Also available as an eBook

Also available as an eBook

Textbook

Introduction to Nutrition and Metabolism Fourth Edition

Organic Chemist’s Desk Reference

David A. Bender

Second Edition

University College London, UK

Thoroughly updated, this fourth edition of a bestseller cut through a wealth of sometimes conflicting new findings to continue to provide a clear introduction to nutrition and metabolism. Via basic biochemistry, it explains the scientific principles underlying our current understanding of interactions between diet and health, examines nutrient function and metabolic pathways, and explores the scientific basis of various dietary goals. New features include a list of key points at the end of each chapter and the addition of open-ended case-based problems. The accompanying CD contains PowerPoint® presentations, self-assessment exercises, a virtual laboratory, and a nutrient analysis program.

Caroline Cooper London, UK

An instructor’s manual is available upon qualifying course adoption

The past 15 years have witnessed immense growth in the field of chemistry and new discoveries have continued to shape its progress. Extensively revised, this new edition of a classic reference contains the very latest data that chemists need access to for experimentation and research. Changes to the second edition include rearranged content, making subjects easier to find; expanded topics from the glossary now presented as separate chapters; updated information on many classic subjects such as mass spectrometry and infrared, ultraviolet, and nuclear magnetic resonance spectroscopy; new sections on chiral separations and crystallography; and cross references to a plethora of web information.

Catalog no. 43129, ISBN: 978-1-4200-4312-9 July 2007, 7 x 10, 440 pp., Soft Cover Suggested Price: $79.95 / £49.99

Catalog no. K10587, ISBN: 978-1-4398-1164-1 July 2010, 7 x 10, 280 pp., Soft Cover Suggested Price: $87.95 / £56.99 Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

7


PCR Technology

Biochemistry / Biomaterials and Medical Devices

Current Innovations, Third Edition

Structural Glycobiology

Edited by

Edited by

Tania Nolan

Elizabeth Yuriev

Sigma Life Science Custom Products, Dorset, UK

Monash Institute of Pharmaceutical Sciences, Australia

Stephen A. Bustin

Paul A. Ramsland

Barts and the London School of Medicine and Dentistry, UK

Centre for Immunology, Burnet Institute, Australia

A technique used to amplify the number of copies of a specific region of DNA, the polymerase chain reaction (PCR) is at the forefront of the dramatic development of biochemistry. This text provides the tools for developing innovative approaches to using this leading technology. It includes theoretical considerations, discussions, and a selection of state-of-the-art techniques for mutation studies, clinical diagnosis, and the detection of foodborne pathogens. This edition also discusses the preparation of PCR experiments, includes examples of analytical PCR divided into qualitative and quantitative applications, and explores preparative methods that address DNA generation for further analysis and in vitro evolution.

Structural glycobiology is a rapidly growing field of research that examines the structural and functional roles of carbohydrates. This book investigates how research findings have revealed key structural and associated biological information on carbohydrates and glycolipids. The first part presents wellestablished experimental approaches for the structural determination of carbohydrate–protein complexes and large glycoprotein assemblies. The second part focuses on theoretical and modeling-based approaches. The third part covers alternative and emerging techniques for yielding structural information on carbohydrates from complex biological samples, and the final part discusses carbohydrates in medicine.

Catalog no. K12140, ISBN: 978-1-4398-4805-0 April 2013, 7 x 10, 448 pp. Suggested Price: $159.95 / £99.00

Catalog no. K12506, ISBN: 978-1-4398-5460-0 September 2012, 6-1/8 x 9-1/4, 347 pp. Suggested Price: $119.95 / £76.99

Also available as an eBook

Also available as an eBook

RNA Nanotechnology and Therapeutics Peixuan Guo

Textbook of Organic Chemistry C. N. Pillai Indian Institute of Technology, Madras

University of Cincinnati, Ohio, USA

8

Textbook

Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world’s foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. In addition, the text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, RNA chemistry for nanoparticle synthesis, and conjugation and labeling. Catalog no. K14577, ISBN: 978-1-4665-0566-7 May 2013, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $179.95 / £114.00

Textbook of Organic Chemistry employs a deductive approach and reduces the need to learn by rote. Each chapter has been developed in a logical and interesting manner that facilitates easy reading and understanding. This approach has been developed and perfected by the author over the course of his tenure as a teacher of organic chemistry. Each chapter provides exercises that test the understanding of the student while strengthening the concepts discussed in the text. Challenging questions are included for those students who want to delve deeper into the subject. Topics of current interest are suggested for preparing project reports. Catalog no. K15172, ISBN: 978-1-4665-5144-2 May 2012, 6 x 9, 640 pp. Suggested Price: $99.95 / £63.99

Also available as an eBook

Engineering of Polysaccharide Materials Skin Bioscience

by Phosphorylase-Catalyzed Enzymatic Chain-Elongation

A Molecular Approach

Jun-ichi Kadokawa and Yoshiro Kaneko

Edited by

Kagoshima University, Japan

This book introduces skin bioscience with a specific focus on the molecular approach. Following the description of the fundamental structure and unique functionality of the skin, it examines the response of the skin to exterior stimulation. It also focuses on the beautification and regeneration of the skin. This book provides readers with the molecular knowledge of the skin and stimulates their interest in further investigation and development of skin bioscience.

Polysaccharides and their related compounds are attracting much attention because of their potential for the applications as new functional materials in many research fields such as medicines, pharmaceutics, foods, and cosmetics. Therefore, precision synthesis of new polysaccharides with well-defined structure is being increasingly important. For this purpose, enzymatic method is a very powerful tool because the reactions proceed in highly stereo- and regiocontrolled manners. This book focuses on advances in the practical synthesis of polysaccharides by the phosphorylase-catalyzed chain-elongation on the basis of the viewpoint of polysaccharide engineering.

Catalog no. N10701, ISBN: 978-981-4364-95-9 February 2013, 6 x 9, 200 pp. Suggested Price: $149.95 / £95.00

Catalog no. N10553, ISBN: 978-981-4364-45-4 December 2012, 6 x 9, 200 pp. Suggested Price: $129.95 / £82.00

Also available as an eBook

Also available as an eBook

Toyoko Imae National Taiwan University of Science & Technology, Taipei

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Bacterial NanoCellulose A Sophisticated Multifunctional Material Edited by

Biological and Biomedical Coatings Handbook

Miguel Gama

Processing and Characterization

University of Minho, Braga, Portugal

Edited by

Paul Gatenholm Dieter Klemm

Sam Zhang Series: Advances in Materials Science and Engineering

The first book dedicated to the potential applications and unique properties of bacterial cellulose (BC), this seminal work covers the basic science, technology, and economic impact of this bulk chemical as well as the companies and patents that are driving the field. It reviews the biosynthesis and properties of BC, including genetics and characterization; discusses the advancing technology as it relates to product development, bioreactors, and production; and analyzes the economic impact of BC on a diverse range of industry applications, including materials and biomaterials, biological and polymer sciences, and electromechanical engineering.

Important in today’s nanotechnology, biological and biomedical coatings have been studied extensively and are currently receiving much attention from researchers. A timely reference for experts and newcomers, this comprehensive handbook explores the latest developments in films and coatings for biological and biomedical applications. An exploration of the fundamental elements of biological and biomedical coatings, the first volume, Processing and Characterization, addresses synthesis, fabrication, and characterization of nanocoatings; the sol-gel method and electrophoretic deposition; thermal and plasma spraying; hydroxyapatite and organically modified coatings, bioceramics and bioactive glass-based coatings, hydrothermal crystallization and selfhealing effects, physical and chemical vapor deposition, layered assembled polyelectrolyte films, and more.

Catalog no. K13216, ISBN: 978-1-4398-6991-8 November 2012, 6-1/8 x 9-1/4, 304 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Biomaterials and Stem Cells in Regenerative Medicine

Biomaterials and Medical Devices

Nanyang Technological University, Singapore

Series: Perspectives in Nanotechnology

Catalog no. K12269, ISBN: 978-1-4398-4995-8 May 2011, 7 x 10, 456 pp. Suggested Price: $146.95 / £94.00 Also available as an eBook

Edited by

Murugan Ramalingam Seeram Ramakrishna National University of Singapore

Serena Best University of Cambridge, UK

This book brings together current knowledge on biomaterials and stem cells in the context of tissue engineering and regenerative medicine. It explores key scientific and clinical aspects, including the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications. Coverage ranges from fundamental principles to advances at the macro, micro, nano, and molecular scales. The book bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for multidisciplinary biomedical research. Catalog no. K13711, ISBN: 978-1-4398-7925-2 July 2012, 6-1/8 x 9-1/4, 564 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Biological and Biomedical Coatings Handbook Applications Edited by

Sam Zhang Nanyang Technological University, Singapore Series: Advances in Materials Science and Engineering

A timely reference for experts and newcomers, this comprehensive handbook explores the latest developments in films and coatings for biological and biomedical applications. Building on the theoretical and methodological fundamentals of coatings as presented in the first volume, Applications covers biological/biomedical implants and other applications of carbon-based materials; control of drug release from coatings; microfluidic and biosensing/bioactive coatings and applications; surfaces and coatings of orthopedic, dental, and other implants; sol–gel-derived hydroxyapatite coatings on metallic implants; impedance spectroscopy; and more.

Biomaterials for MEMS

Catalog no. K12270, ISBN: 978-1-4398-4996-5 May 2011, 7 x 10, 520 pp. Suggested Price: $146.95 / £94.00

Edited by

Also available as an eBook

Mu Chiao University of British Columbia, Vancouver, Canada

Jung-Chih Chiao University of Texas at Arlington, USA

This book serves as a guide for practicing engineers, researchers, and students interested in MEMS devices and biomaterials and biomedical applications. It is also suitable for engineers and researchers interested in MEMS and its applications but who do not have the necessary background in biomaterials. The book highlights important features and issues of biomaterials that have been used in MEMS and biomedical areas, including the fabrication of devices using biomaterials, biocompatible coatings and issues, thin-film biomaterials and MEMS for tissue engineering, and applications involving MEMS and biomaterials.

Biological and Biomedical Coatings Handbook Two-Volume Set

Catalog no. N10421, ISBN: 978-981-4241-46-5 March 2011, 7 x 10, 292 pp. Suggested Price: $149.95 / £95.00

Catalog no. K11126 ISBN: 978-1-4398-2125-1 May 2011, 7 x 10, 976 pp. Suggested Price: $259.95 / £166.00

Also available as an eBook

Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

9


Biomaterials Principles and Practices Edited by

Joyce Y. Wong

Biosensors

Boston University, Massachusetts, USA

Theory and Applications

Joseph D. Bronzino Simsbury, Connecticut, USA

Donald R. Peterson

Biomaterials and Medical Devices

University of Connecticut, Farmington, USA

Most current applications of biomaterials involve structural functions, even in those organs and systems which are not primarily structural in their nature, or very simple chemical or electrical functions. Complex chemical functions such as those of the liver and complex electrical or electrochemical functions such as those of the brain and sense organs cannot be carried out by biomaterials at this time. With these basic concepts in mind, this book focuses on biomaterials consisting of different materials such as metallic, ceramic, polymeric, and composite. It highlights the impact of recent advances in the area of nano- and microtechnology on biomaterial design.

University of Pennsylvania, Philadelphia, USA

This book is an overview of the basic theories of operation for a number of specific types of biosensor transducers that have been investigated, with a general survey of some of the many applications using various biological elements that have been tested to date. A major portion of this book has been devoted to electrochemical transducers, since they have been most widely used. Catalog no. TX9757, ISBN: 978-0-87762-975-7 August 1995, 6 x 9, 232 pp. Suggested Price: $125.95 / £79.99

Catalog no. K13339, ISBN: 978-1-4398-7251-2 December 2012, 7 x 10, 278 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Carbon Nanotubes Bionanomaterials for Dental Applications Edited by

Mieczyslaw Jurczyk Poznan University of Technology, Poland

10

Donald G. Buerk

Recently, chemical, physical, and mechanical processes for the fabrication of metal/ alloy-ceramic nanocomposites with a unique microstructure have been developed. These processes permit the control of microstructural properties such as the size of pore openings, surfaces properties, and the nature of the base metal/alloy. This book presents information about the structure and characteristics of new dental nanomaterials, corrosion behavior of metallic biomaterials and implants as well as methods of surface improvement of implants by means of nanoengineering, which decides the biocompatibility of the insert. It thoroughly explains the osseointegration from a biological viewpoint and early tissue response. Catalog no. N10474, ISBN: 978-981-4303-83-5 August 2012, 6 x 9, 428 pp. Suggested Price: $149.95 / £95.00

From Bench Chemistry to Promising Biomedical Applications Edited by

Giorgia Pastorin National University of Singapore

This book represents a critical evaluation of the most recent discoveries about carbon nanotubes and includes a cautious description of their impact on personal health and environmental pollution. It also offers an overview of the main research groups around the world which have been focusing their efforts on the exploitation of this intriguing material, with the purpose of inspiring young scientists to follow their pathway. Catalog no. N10419, ISBN: 978-981-4241-68-7 January 2011, 7 x 10, 156 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Also available as an eBook

Biosensors and Environmental Health Edited by

Victor R. Preedy King’s College Hospital, London, UK

Vinood Patel

Handbook of Active Materials for Medical Devices Advances and Applications

University of Westminster, London, UK

Edited by

This book provides key facts that can be applied to other areas of health and disease. It covers personal toxicity testing, soil and risk assessment, pesticide, insecticides, parasites, nitrate, endocrine disruptors, heavy metals, food contamination, whole cell bioreporters, bacterial biosensors, antibody-based biosensors, enzymatic, amperometric and electrochemical aspects, quorum sensing, DNA-biosensors, cantilever biosensors, bioluminescence, and other methods and applications. The contributors are leading authorities and the book is essential reading for environmental scientists, toxicologists, medical doctors, health care professionals, pathologists, biologists, biochemists, chemists and physicists, and general practitioners as well as those interested in disease and sciences in general.

Andres Diaz Lantada

Catalog no. K16344, ISBN: 978-1-57808-735-8 August 2012, 6-1/8 x 9-1/4, 350 pp. Suggested Price: $119.95 / £76.99 Also available as an eBook

Universidad Politecnica de Madrid, Spain

This book covers biodevices, mainly implantable or quirurgical, for the diagnosis or treatment of different pathologies, which benefit from the use of active materials as sensors or actuators. The research presented in this book helps further development of medical devices, based on the additional functionalities that the use of active or “intelligent” materials, both as sensors and actuators. The main results covered may help with the industrial expansion of this kind of materials as part of more complex systems. Catalog no. N10471, ISBN: 978-981-4303-36-1 September 2011, 6 x 9, 350 pp. Suggested Price: $249.95 / £159.00 Also available as an eBook

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Marine Biomaterials

Preparation, Toxicity, and Applications

Characterization, Isolation and Applications

Edited by

Edited by

Dan Peer

Se-Kwon Kim

Tel Aviv University, Israel

Pukyong National University, Busan, South Korea

This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers, lipids, and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nanoproteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; the use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book covers theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.

Presenting a groundbreaking platform to assist in development of new biotechnology start-ups and enterprises, this book describes current trends in marine materials for a range of fields including tissue engineering, drug delivery, bioenergy, and adhesive products from preliminary research to clinical trial. Essential reading for both the novice and expert alike, it details the isolation and characterization of appropriate materials, extraction methods for the extraction and application of marine materials, the viability of low-cost marine biomaterials, and the potential role of the biological applications to diseases such as inflammation, diabetes, arthritis, and cancer.

Catalog no. N10498, ISBN: 978-981-4316-46-0 January 2012, 6 x 9, 424 pp. Suggested Price: $149.95 / £95.00

Catalog no. K14576, ISBN: 978-1-4665-0564-3 April 2013, 7 x 10, 848 pp. Suggested Price: $189.95 / £121.00 Also available as an eBook

Also available as an eBook

Hydroxyapatite Coatings for Biomedical Applications Edited by

Materials Science of DNA Edited by

Jung-II Jin Korea University, Seoul, South Korea

Biomaterials and Medical Devices

Handbook of Harnessing Biomaterials in Nanomedicine

James Grote

Sam Zhang Nanyang Technological University, Singapore Series: Advances in Materials Science and Engineering

This handbook covers developments in processing and property characterization and applications of hydroxyapatite (HA), providing a timely resource for active researchers and newcomers to the field. It details HA coatings and use in dental implants, biomimetic HA materials, electrochemical and pulsed laser deposition, drug delivery, and more. In an approach that differs from traditional handbooks, it contains more than just data such as tables and figures. It is written in such a way that seasoned professionals at every level will find it a valuable data source that gives them indispensable help in their research. Catalog no. K14030, ISBN: 978-1-4398-8693-9 April 2013, 6-1/8 x 9-1/4, 784 pp. Suggested Price: $219.95 / £140.00

AFRL/RXPS, Wright Patterson Air Force Base, Ohio, USA

As interest continues to grow, DNA is expected to become focal to nanobiotechnology because of its structural and chemical characteristics. With chapters written by experts in their respective fields, this text chiefly focuses on the rapidly growing fields of nanoscience, nanotechnology, and biotechnology. It is the first to address the materials science facet of DNA, rather than its chemical, biochemical, or biological aspects. It includes tables, graphs, equations, and an ancillary CD-ROM to provide understanding of DNA and the great potential of this biopolymer as advanced material. Catalog no. K11352, ISBN: 978-1-4398-2741-3 December 2011, 6-1/8 x 9-1/4, 338 pp. Suggested Price: $119.95 / £76.99 Also available as an eBook

Also available as an eBook

Multiporphyrin Arrays

ISO 13485 A Complete Guide to Quality Management in the Medical Device Industry Itay Abuhav

Fundamentals and Applications Edited by

Dongho Kim Institute for NanoBio Molecular Assemblies, Seoul, South Korea

The United States and European Union now require the ISO 13485 Standard certification for medical device manufacturers. Written by an experienced industry professional, this practical book provides a complete guide to the ISO 13485 Standard certification for medical device manufacturing in terms of quality control. It covers all the requirements of ISO 13485 and offers a stepby-step comparison between the ISO 13485 and ISO 9001, enabling a sound understanding of these new procedures.

This book provides a comprehensive review of the fundamentals and applications of multiporphyrin arrays ranging from basic spectroscopic features to a wide range of promising applications such as molecular wires, switches, sensors, artificial photosynthetic devices, and dye-sensitized solar cells based on a variety of multiporphyrin architectures using covalent and/or noncovalent molecular assemblies. Particularly, it focuses on energy and electron transfer processes occurring in multiporphyrin arrays in various environments such as singlemolecule level, composite materials, LB films, and solid surface to provide better understanding of photofunctional molecular architectures.

Catalog no. K12946, ISBN: 978-1-4398-6611-5 October 2011, 6-1/8 x 9-1/4, 374 pp. Suggested Price: $139.95 / £89.00

Catalog no. N10500, ISBN: 978-981-4316-60-6 January 2012, 6 x 9, 828 pp. Suggested Price: $249.95 / £159.00

Also available as an eBook

Also available as an eBook

Hinterforst, Switzerland

For more information and a complete list of titles, visit us at www.crcpress.com

11


Nanofabrication Handbook Edited by

Stefano Cabrini

Biomaterials and Medical Devices 12

Self-Healing at the Nanoscale Mechanisms and Key Concepts of Natural and Artificial Systems

Lawrence Berkeley National Laboratory, Berkeley, California, USA

Edited by

Satoshi Kawata

Vincenzo Amendola and Moreno Meneghetti

Osaka University, Japan

Università di Padova, Italy

This comprehensive handbook presents a unique collection of new and important approaches to nanofabrication, from electron beam lithography, focused ion beam, and optical lithography to two-photon lithography, self assembly, and plasmonic nanolithography. Contributors from leading research facilities and academic institutions offer hands-on instructions and examples and pave the way for future research. The practical information provided in the book gives readers a foundation to enter the complex world of nanofabrication and helps them to select the proper fabricating technique for their experiments.

Self-healing materials can repair damage caused by their activity, similar to how biological systems heal themselves after being wounded. This book presents a general strategy and key concepts of self-healing systems, repairing mechanisms at the nanoscale, and the role of nanostructures in these systems. The text covers natural and artificial systems, including nanostructured and macroscopic systems. It also reviews a series of systems that show potential for building selfhealing devices.

Catalog no. 90526, ISBN: 978-1-4200-9052-9 February 2012, 8-1/2 x 11, 546 pp. Suggested Price: $129.95 / £82.00

Catalog no. K12542, ISBN: 978-1-4398-5473-0 December 2011, 6-1/8 x 9-1/4, 463 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Also available as an eBook

Textbook

Polymer and Polymer-Hybrid Nanoparticles From Synthesis to Biomedical Applications

Ultrasonic and Electromagnetic NDE for Structure and Material Characterization Engineering and Biomedical Applications

Stanislav Rangelou and Asterios Pispas

Edited by

Written for graduate students and researchers in the fields of chemistry, pharmacy, nanosciences, and biomedical engineering, this timely reference reviews polymer synthesis and macromolecular design and various applications of polymer-based nanomaterials in bionanotechnology and medicine. It provides a description of the current state of the art, summarizing important developments in the field and condensing the relevant research into a comprehensive reference. Differing from other references of similar topic, this book provides an interdisciplinary bridge between polymer synthesis and characterization and biomedical aspects. It also provides a comprehensive overview of synthesis strategies and nanostructures applicable to the controlled delivery of drugs.

Tribikram Kundu

Catalog no. K13166, ISBN: 978-1-4398-6907-9 April 2013, 6-1/8 x 9-1/4, 560 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Polymers for Vascular and Urogenital Applications

The University of Arizona, Tucson, USA

Most books on NDE focus either on the theoretical background or on advanced applications. Bridging the gap, this book brings together the principles, equations, and applications of ultrasonic and electromagnetic NDE in a single, authoritative resource. It begins with the fundamentals of mechanics and electromagnetic theory, derives the basic equations, and then, step by step, covers state-of-theart topics and applications. These include structural health monitoring, acoustic microscopy, terahertz imaging, and more. Written in plain language by some of the world’s leading experts, this book appeals to students as well as practicing engineers and researchers. A solutions manual is available upon qualifying course adoption

Catalog no. K11655, ISBN: 978-1-4398-3663-7 June 2012, 7 x 10, 890 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Edited by

Shalaby W. Shalaby Poly-Med Inc., Anderson, South Carolina, USA

Karen J.L. Burg Clemson University, South Carolina, USA

Waleed Shalaby Chadds Ford, Pennsylvania, USA

Usability Testing of Medical Devices

Series: Advances in Polymeric Biomaterials

Michael E. Wiklund, Jonathan Kendler, and Allison S. Yale

In a carefully crafted, multidisciplinary, skillfully focused format, this book covers attributes of polymers used for vascular, urological, and gynecological materials. It provides a brief analysis of how the use of polymers in vascular and urogenital applications has evolved in the past five decades and outlines their common and specific functional requirements. It features small, readable monographs that provide a brief description of the evolving role of a particular material, and present topics in highly integrated, well-balanced, authoritatively prepared segments on materials processing and in vitro and in vivo evaluation, complete with case studies.

Informative, practical, and engaging, this handbook covers how to conduct usability tests of medical devices. Recognizing that the intended readers are busy and disinclined to read lengthy textbooks, this book has been carefully designed to be concise and visual, allowing readers to jump from one section to another as needed. The book provides a general understanding of usability testing and reviews key concepts. It highlights the challenges of validating that protects against dangerous errors that could lead to patient injury and death.

Catalog no. 76949, ISBN: 978-1-4200-7694-3 May 2012, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $179.95 / £114.00

Catalog no. K10595, ISBN: 978-1-4398-1183-2 December 2010, 6-1/8 x 9-1/4, 412 pp. Suggested Price: $76.95 / £48.99

Also available as an eBook

Also available as an eBook

Wiklund Research & Design, Inc., Concord, Massachusetts, USA

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The Biomedical Engineering Handbook Fourth Edition, Four-Volume Set

Biologically Inspired Robotics Edited by

Joseph D Bronzino Donald R. Peterson

Yunhui Liu

University of Connecticut, Farmington, USA

Dong Sun

Series: Electrical Engineering Handbook

City University of Hong Kong, Kowloon

The definitive “bible” for the field of biomedical engineering, this collection of volumes is a major reference for all practicing biomedical engineers and students. Now in its fourth edition, this work presents a substantial revision, with all sections updated to offer the latest research findings. New sections address drugs and devices, personalized medicine, and stem cell engineering. Also included is a historical overview as well as a special section on medical ethics. This set provides complete coverage of biomedical engineering fundamentals, medical devices and systems, computer applications in medicine, and molecular engineering.

This reference contains cutting-edge material—considerably expanded and with additional analysis—from the 2009 IEEE International Conference on Robotics and Biomimetics. The 16 chapters cover biologically inspired robot design and control, micro/nano robots for bio-systems and biomedicine, biological measurement and actuation, and applications of robotics technology to biological problems. A state-of-the-art resource for graduate students and researchers in control engineering, robotics, and biomedical engineering, this text helps readers understand the technology and principles in this emerging field. It includes a wealth of illustrations and equations.

Catalog no. K11205, ISBN: 978-1-4398-2533-4 May 2013, 7 x 10, 4500 pp. Suggested Price: $309.95 / £197.00 Also available as an eBook

Catalog no. K12555, ISBN: 978-1-4398-5488-4 December 2011, 6-1/8 x 9-1/4, 340 pp. Suggested Price: $104.95 / £66.99 Also available as an eBook

Individual volumes also available

The Biomedical Engineering Handbook Fourth Edition, Biomedical Engineering Fundamentals The first volume of The Biomedical Engineering Handbook, Fourth Edition provides comprehensive coverage of the latest research findings. Known as the bible of biomedical engineering, the handbook set the standard against which all other references of this nature are measured. The new edition features a new coauthor, coverage of medical ethics, historical perspective, and updated coverage in all sections. It provides an important resource for biomedical engineers and students. Catalog no. K11198, ISBN: 978-1-4398-2518-1 May 2013, 7 x 10, 1200 pp., Soft Cover Suggested Price: $189.95 / £121.00 Also available as an eBook

The Biomedical Engineering Handbook, Fourth Edition, Medical Devices and Systems Catalog no. K11201, ISBN: 978-1-4398-2525-9 May 2013, 7 x 10, 1200 pp., Soft Cover Suggested Price: $189.95 / £121.00

Textbook

Biomechanics of the Upper Limbs Mechanics, Modeling and Musculoskeletal Injuries, Second Edition Andris Freivalds The Pennsylvania State University, University Park, USA

Over the past two decades, the growth in computer-related jobs has led to considerable increase in the number of work-related musculoskeletal disorders in the upper limbs. Now in its second edition, this comprehensive text is now expanded to include recent findings regarding job stressors and a variety of ergonomic solutions. It provides up-to-date research on the biomechanics of the upper limbs and the mechanics of neuromuscular systems. It covers risk factors for various disorders and tools used to identify their causes. A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. 91190, ISBN: 978-1-4200-9119-9 February 2011, 7 x 10, 564 pp. Suggested Price: $125.95 / £79.99 Also available as an eBook

Also available as an eBook

The Biomedical Engineering Handbook, Fourth Edition, Molecular Engineering Catalog no. K11202, ISBN: 978-1-4398-2527-3 June 2013, 7 x 10, 1642 pp. Suggested Price: $189.95 / £121.00

Textbook

A Laboratory Manual in Biophotonics Vadim Backman Northwestern University, Evanston, Illinois, USA

Also available as an eBook

Adam Wax

The Biomedical Engineering Handbook, Fourth Edition, Tissue Engineering and Artificial Organs Catalog no. K11204, ISBN: 978-1-4398-2530-3 May 2013, 7 x 10, 1200 pp., Soft Cover Suggested Price: $189.95 / £121.00 Also available as an eBook

Biomedical Engineering

The Chinese University of Hong Kong

Hao Zhang

The increasing use of optical techniques for biomedical applications has led to significant interest in biophotonics as a growing field. From its basic concepts to more advanced topics and applications, this book provides a complete guide to biophotonics. The author offers both descriptive and quantitative perspectives as well as a comprehensive overview of major areas of research in the field. The text includes coverage of topics such as light tissue interaction, optical instrumentation, microscopic and macroscopic tissue imaging, tissue spectroscopy, therapeutic applications of optics, and molecular imaging. Catalog no. K10524, ISBN: 978-1-4398-1051-4 June 2013, 7 x 10, 500 pp. Suggested Price: $119.95 / £62.99

For more information and a complete list of titles, visit us at www.crcpress.com

13


Textbook Edited by

Advanced Materials for Joint Implants

Cato T. Laurencin and Yusuf Khan

Giuseppe Pezzotti

Regenerative Engineering

Biomedical Engineering

University of Connecticut Health Center, Farmington, USA

Kyoto Institute of Technology, Japan

Regenerative engineering is the intersection of regenerative medicine and tissue engineering. Regenerative medicine focuses on the biological aspects of tissue regeneration via stem cells, factors, and cytokines, while tissue engineering focuses on the integration of materials science and life sciences. This book integrates these two areas, presenting each concept in the framework of regenerative engineering. Through the combination of fundamental lecturebased teaching and problem-based learning approaches, it is the goal of this textbook to develop students into future researchers capable of completing the translation of their work from the benchtop to the bedside.

This book details cutting-edge research in bioceramics science based on an interdisciplinary approach that directly bridges orthopedic concepts to surface science, physical chemistry, biomedical optics and nanomechanics. Raman and cathodoluminescence spectroscopy are, among more conventional spectroscopic characterization techniques, cited in the book, used to their most advanced extents to unveil molecular scale phenomena of both chemical and mechanical origin occurring at the sliding surfaces of bioceramic joints. The concepts are relevant to the development of new biomaterials.

Catalog no. K10724, ISBN: 978-1-4398-1412-3 March 2013, 7 x 10, 400 pp. Suggested Price: $99.95 / £63.99

Also available as an eBook

Also available as an eBook

Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery Edited by

Advances in Therapeutic Engineering

Chengtie Wu Yin Xiao

Edited by

Queensland University of Technology, Institute of Health and Biological Innovation, Brisbane, Australia

Wenwei Yue, Subhagata Chattopadhyay, Teik-Cheng Lim, and Rajendra Acharya

Jing Chang Shanhghai Institute of Ceramics, Chinese Academy of Science

14

Catalog no. N10574, ISBN: 978-981-4316-88-0 August 2012, 6 x 9, 400 pp. Suggested Price: $179.95 / £114.00

This book brings together the latest research advances in bioactive inorganic materials for bone repair, concentrating on mesoporous bioactive glasses and silicate-based bioceramics. Specialists in the bioceramic field contribute their interesting research progress in the book, mainly including: silica nanospheres with core-shell structure and specific properties for controllable drug delivery; novel 3D-printing technique to prepare advanced bioceramic scaffolds for bone tissue engineering application; and biomimetic pareparation, controllable crystal growth as well as biomineralization of bioceramics. Catalog no. K15196, ISBN: 978-1-4665-5199-2 March 2013, 6-1/8 x 9-1/4, 248 pp. Suggested Price: $189.95 / £99.95

This comprehensive, edited book brings together topics in therapeutic and rehabilitative engineering, ranging from prosthetics to sensory substitution and medical robotics. Drawing on the expertise of a multidisciplinary field of contributors, it discusses both diagnostic and therapeutic aspects of health care and rehabilitation, including healthcare informatics, biomedical signal processing, sensors, and robotic prosthetics. Presenting a system-level approach to therapeutic engineering, it explores the current state and future directions of this rapidly advancing and cutting-edge field. Catalog no. K13287, ISBN: 978-1-4398-7173-7 December 2012, 6-1/8 x 9-1/4, 494 pp. Suggested Price: $179.95 / £109.00 Also available as an eBook

Also available as an eBook

Advanced Biophotonics Tissue Optical Sectioning Edited by

Ruikang K. Wang University of Washington, Seattle, USA

Valery V Tuchin

Ambient Assisted Living Nuno M. Garcia, Joel Jose P.C. Rodrigues, Dirk Christian Elias, and Miguel Sales Dias

Saratov State University, Russia

Rehabilitation Science in Practice Series

Series in Optics and Optoelectronics

This reference provides an overview of optical imaging and manipulation technologies in biophotonics, covering both basic and advanced optical imaging techniques. It reviews the principles and fundamentals of bioimaging and molecular imaging/manipulation techniques. It also presents an overview of instrumentation, basic algorithms, and data processing methods. Accessible to students and researchers, the book discusses a range of application areas, including established and newer methodologies in biotechnology, biomedical engineering, biophysics, medicine, and pharmacology.

Written for students, practitioners and users of Ambient Assisted Living (AAL), this comprehensive reference covers methods, concepts, systems, devices, and services that provide unobtrusive support for the daily needs of an assisted person. The reference also provides extensive coverage of applications, software, and information management for AAL, as well as coverage of the latest hardware and software for ergonomic design pertaining to AAL. A key concept covered within the reference is ambient intelligence, which refers to electronic environments that are sensitive and responsive to the presence of people. References are provided at the end of each chapter for additional study.

Catalog no. K14253, ISBN: 978-1-4398-9581-8 June 2013, 7 x 10, 576 pp. Suggested Price: $199.95 / £127.00

Catalog no. K13212, ISBN: 978-1-4398-6984-0 January 2013, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $149.95 / £95.00

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Also available as an eBook

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Textbook

Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation

Assistive Technology for Blindness and Low Vision Edited by

Second Edition

Roberto Manduchi and Sri Kurniawan

Robert B. Northrop

University of California, Santa Cruz, USA

University of Connecticut, Storrs, USA

This book helps biomedical engineers understand and design signal conditioning systems using analog integrated circuits. It explains the electronic components and subsystems—the “building blocks”—that are used in ECG, EEG, EMG, ERG, tomographic images, biochemical spectrograms, and other crucial medical applications. This second edition has been substantially updated and revised. It now features a glossary, new end-of-chapter problems, and three new chapters that address wireless patient monitoring using UHF telemetry; power amplifiers and their applications to biomedical instruments; and RFID, GPS, and ultrasonic tags used in ecological research. A solutions manual and figure slides available upon qualifying course adoption

Catalog no. K12982, ISBN: 978-1-4398-6669-6 March 2012, 7 x 10, 578 pp. Suggested Price: $119.95 / £76.99

This book provides a comprehensive overview of the current state of the art in assistive technology for persons with visual impairment, as well as coverage into promising new research directions. Beginning with a brief overview of the pathology and psychophysical aspects of low vision and blindness, the text proceeds with in-depth descriptions of current technology to support independent mobility and orientation, information access (printed information, tactile information, and computers), and life activities (education, work, entertainment), as well as future directions related to the technology for blindness and visual impairment. Catalog no. K13276, ISBN: 978-1-4398-7153-9 October 2012, 6-1/8 x 9-1/4, 441 pp. Suggested Price: $119.95 / £76.99 Also available as an eBook

Also available as an eBook

Biochemical Sensors Mimicking Gustatory and Olfactory Senses

Articular Cartilage Kyriacos Athanasiou, Eric Darling, Grayson D. DuRaine, Jerry Hu, and A. Hari Reddi Articular cartilage injuries, which are well known for their inability to heal, often degenerate inexplicably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. However, over the past two decades, the swift growth and development of new knowledge and technologies for cartilage formation, pathology and repair have been exciting and inspirational. Written by world-class experts, this book covers all the latest research and clinical applications related to cartilage tissue engineering. The text explores the role of nanotechnology and also provides extensive references at the end of each chapter. Catalog no. K12457, ISBN: 978-1-4398-5324-5 March 2013, 6-1/8 x 9-1/4, 464 pp. Suggested Price: $169.95 / £108.00

Edited by

Kiyoshi Toko Kyushu University, Fukuoka, Japan

This book is the first to comprehensively treat sensors for gustatory and olfactory senses. It will be highly useful to students and researchers in a wide variety of scientific fields and also to those in the fields of foods, perfumes, medicines, and robotics as the sensor applications. Catalog no. N10675, ISBN: 978-981-4267-07-6 March 2013, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

15 Textbook

Also available as an eBook

Biofluid Mechanics

Assistive Technology Assessment Handbook

The Human Circulation, Second Edition Krishnan B. Chandran

Edited by

University of Iowa, Iowa City, USA

Stefano Federici

Ajit P. Yoganathan

University of Perugia, Italy

Georgia Institute of Technology, Atlanta, USA

Marcia Scherer Institute for Matching Person & Technology, Webster, New York, USA Rehabilitation Science in Practice Series

Assistive technology plays a fundamental role in facilitating the social integration of people with physical, sensory, communication, and cognitive disabilities. This handbook presents the assessment tools that are essential in a center for technical aid, common in Italy, where multidisciplinary teams match the technology to the person who needs it. The book also describes the roles of members of the assessment team—including the profession of psychotechnologist—and reviews cutting-edge technologies for rehabilitation and independent living. Emphasizing the well-being of the person with disabilities, it proposes an ideal model of the assessment process and outlines how the model can be applied in practice internationally. Catalog no. K11756, ISBN: 978-1-4398-3865-5 March 2012, 7 x 10, 484 pp. Suggested Price: $139.95 / £82.00

Biomedical Engineering

Rehabilitation Science in Practice Series

Series: Biomedical Engineering

Stanley E. Rittgers University of Akron, Ohio, USA

This classroom-tested text teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition includes improved figures, additional examples, and more problems at the end of each chapter. It also presents a new chapter on the computational fluid dynamic analysis of the human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas. A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. K12006, ISBN: 978-1-4398-4516-5 February 2012, 6-1/8 x 9-1/4, 451 pp. Suggested Price: $104.95 / £66.99 Also available as an eBook

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Textbook

Biological and Bioenvironmental Heat and Mass Transfer Ashim K. Datta

Edited by

Raymond Tong Kaiyu

Biomedical Engineering

Cornell University, Ithaca, New York, USA

Hong Kong Polytechnic University, Hung Hom, Kowloon

Providing a foundation in heat and mass transport, this book covers engineering principles of heat and mass transfer. The author discusses biological content, context, and parameter regimes and supplies practical applications for biological and biomedical engineering, industrial food processing, environmental control, and waste management. The book contains end-of-chapter problems and sections highlighting key concepts and important terminology. The book offers cross-references for easy access to related areas and relevant formulas, as well as detailed examples of transport phenomena, and descriptions of physical processes. It covers mechanisms of diffusion, capillarity, convection, and dispersion.

This book presents experts’ insights into the emerging technologies and developments that are being or will be utilized in the medical profession to meet a variety of clinical challenges. It demonstrates the application of biomechatronics to provide better care and service. It also incorporates new and exciting multidisciplinary areas of research across the medical and engineering fields, such as robotic therapeutic training system for stroke rehabilitation, exoskeletons for daily activities on persons with disability, functional electrical stimulation, and wireless active capsule endoscopy. Each chapter provides substantial background material relevant to the particular subject.

A solutions manual is available upon qualifying course adoption

Catalog no. N10425, ISBN: 978-981-4241-61-8 August 2011, 7 x 10, 250 pp. Suggested Price: $149.95 / £95.00

Catalog no. DK1966, ISBN: 978-0-8247-0775-0 March 2002, 8-1/2 x 11, 424 pp. Suggested Price: $109.95 / £69.99 Also available as an eBook

Biomechanics of Human Motion Applications in the Martial Arts Emeric Arus International Sendo-Ryu Karatedo Federation, Astoria, New York, USA

16

Biomechatronics in Medicine and Health Care

This book provides an overview of human motion studies (biomechanics) using martial arts as extensive examples and references to fundamental theory. It covers in depth the anatomical foundation of biomechanics, the biomechanical and physiological foundation of human motion, and fundamentals of biomechanics. The book begins with musculoskeletal anatomy of the most important muscles and their functions. The author describes the biomechanical and physiological foundations of human motion. He covers kinematics and kinetics—the core of biomechanics—and includes examples for martial arts and sports activities that emphasize the concepts described. Catalog no. K15991, ISBN: 978-1-4665-6323-0 December 2012, 6-1/8 x 9-1/4, 520 pp., Soft Cover Suggested Price: $79.95 / £49.99 Also available as an eBook

Also available as an eBook

Biomedical Applications of Mesoporous Ceramics Drug Delivery, Smart Materials, and Bone Tissue Engineering Maria Vallet-Regi, Miguel Manzano Garcia, and Montserrat Colilla Universidad Complutense de Madrid, Spain

This book provides a comprehensive overview of silica-based mesoporous materials with special attention given to their use in drug delivery systems, sophisticated stimuli-responsive materials, and bone tissue engineering. The text provides a comprehensive overview of the basic aspects of the properties of mesoporous materials, with a focus on textural properties such as surface and porosity. Starting from this consolidated knowledge, it then addresses various aspects of more sophisticated stimuli-responsive materials, where drugs can be encapsulated inside the porous framework and then released when desired. The final chapters are dedicated to bone tissue engineering. Catalog no. K13908, ISBN: 978-1-4398-8307-5 November 2012, 6-1/8 x 9-1/4, 224 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Textbook

Biomechanics Principles and Practices Edited by

Donald R. Peterson University of Connecticut, Farmington, USA

Joseph D. Bronzino Simsbury, Connecticut, USA

Biomechanics: Principles and Practices draws on material from the biomechanics section of The Biomedical Engineering Handbook, Fourth Edition, and includes additional chapters containing highly relevant, cutting-edge material dealing with cellular mechanics. Edited by Donald A. Peterson and Joseph D. Bronzino, this comprehensive reference brings together contributions by world-class experts in the field. Offering an overview of major research topics in biomechanics, this is a useful resource for practitioners, scientists, and researchers in biomechanics as well as bioengineering graduate students studying biomechanics, human performance engineering, and human factors.

Biomedical Engineering Principles Second Edition Arthur B. Ritter, Vikki Hazelwood, and Antonio Valdevit Stevens Institute of Technology, Hoboken, New Jersey, USA

Alfred Ascione Alcatel-Lucent Technologies, New Jersey, USA

Integrating engineering, medicine, biology, and physics, this book clearly defines basic principles in image processing and biomechanics, modeling physiological processes, and bioelectric signal analysis to build a solid understanding of devices and designs for improved functioning of the human body. It includes cutting-edge discussions of tissue engineering, cardiovascular components, bone regrowth, and nerve regeneration. Other topics include technologies at the forefront of cardiac care, such as total artificial hearts, left ventricular assist devices, and stents, as well as issues related to minimally invasive and robotic surgery, next-generation imaging devices, and nanodevices. A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. K13252, ISBN: 978-1-4398-7098-3 April 2013, 7 x 10, 350 pp. Suggested Price: $139.95 / £89.00

Catalog no. K10621, ISBN: 978-1-4398-1232-7 May 2011, 6-1/8 x 9-1/4, 540 pp. Suggested Price: $104.95 / £66.99

Also available as an eBook

Also available as an eBook

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Biomedical Photonics Handbook Second Edition, Three-Volume Set

Biomedical Sensors and Instruments Second Edition Tatsuo Tagawa Waseda University, Tokorozawa, Saitama, Japan

Edited by

Toshiyo Tamura

Duke University, Durham, North Carolina, USA

Chiba University, Chiba, Japan

This handbook presents the most recent technological advances and applications in the areas of biomedical photonics. This second edition contains introductory material and covers the state-of-the-art methods and instrumentation for biomedical photonic technologies. It integrates interdisciplinary research and development critically needed for scientists, engineers, manufacturers, teachers, students, and clinical providers to learn about the most recent advances and predicted trends in instrumentation and methods as well as clinical applications in important areas of biomedical photonics. Extensive references are provided to enhance further study.

Biomedical sensors are essential instruments for acquiring many types of medical and biological data. From the underlying principles to practical applications, this new book provides an easy-to-understand introduction to the various kinds of biomedical sensors. This updated handbook presents state-of-the-art information, including discussions of biomedical sensors for measurements of pressure, flow, motion, temperature, heat flow, evaporation, biopotential, biomagnetism, and chemical quantities.

Catalog no. K10244, ISBN: 978-1-4398-0444-5 June 2013, 7 x 10, 3000 pp. Suggested Price: $249.95 / £159.00

Catalog no. 9078X, ISBN: 978-1-4200-9078-9 March 2011, 7 x 10, 423 pp. Suggested Price: $146.95 / £94.00

Also available as an eBook

Also available as an eBook

Individual volumes also available

Biomedical Technology and Devices Handbook

The Biomedical Photonics Handbook

P. Åke Öberg Linköping University, Sweden

Second Edition

Second Edition, Biomedical Diagnostics

James Moore Duncan Maitland

Edited by

Texas A&M, College Station, USA Handbook Series for Mechanical Engineering

Tuan Vo-Dinh Duke University, Durham, North Carolina, USA

Catalog no. 8514X, ISBN: 978-1-4200-8514-3 June 2013, 7 x 10, 800 pp., Soft Cover Suggested Price: $189.95 / £121.00 Also available as an eBook

The Biomedical Photonics Handbook Second Edition, Fundamentals, Devices, and Techniques Edited by

Fully revised since its original publication, this reference illuminates the equipment, devices, and techniques used in modern medicine to diagnose, treat, and monitor human illnesses. With topics ranging from basic procedures like blood pressure measurements to cutting-edge imaging equipment, biological tests, and genetic engineering, the book is organized to navigate smoothly from simple procedures and concepts to more sophisticated and complex ones. Each section contains a description of the technique, its technical considerations, and its use according to its applications and relevant body systems. There are ten new chapters presenting the most up-to-date information available. Catalog no. K12728, ISBN: 978-1-4398-5959-9 April 2013, 7 x 10, 1000 pp. Suggested Price: $189.95 / £121.00 Also available as an eBook

Tuan Vo-Dinh Duke University, Durham, North Carolina, USA

Catalog no. 85123, ISBN: 978-1-4200-8512-9 June 2013, 7 x 10, 800 pp., Soft Cover Suggested Price: $189.95 / £121.00

Textbook

BioMEMS

Also available as an eBook

The Biomedical Photonics Handbook Second Edition, Therapeutic and Advanced Biophotonics Edited by

Tuan Vo-Dinh Duke University, Durham, North Carolina, USA

Catalog no. 85166, ISBN: 978-1-4200-8516-7 June 2013, 7 x 9, 800 pp., Soft Cover Suggested Price: $189.95 / £121.00 Also available as an eBook

Biomedical Engineering

Tuan Vo-Dinh

Science and Engineering Perspectives Simona Badilescu and Muthukumaran Packirisamy Concordia University, Montreal, Canada

Covering often overlooked areas in the field of bioMEMS, this volume spans topics associated with biomolecules and complex biological entities, as well as subjects directly linked to the design, fabrication, and characterization of devices. Unlike other references, this text aids in the fundamental physicochemical understanding of biological processes relevant to the performance of various biosensing devices. Useful for upper-level undergraduate and graduate students enrolled in engineering programs, the book includes problems in each chapter, in addition to case studies that provide real-life examples. A solutions manual is available upon qualifying course adoption

Catalog no. K10877, ISBN: 978-1-4398-1699-8 April 2011, 7 x 10, 368 pp. Suggested Price: $104.95 / £66.99 Also available as an eBook

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17


Biomimetics and Ocean Organisms

Bionanotechnology II

An Engineering Design Perspective

Global Prospects

Iain A. Anderson Julian Vincent

Edited by

Biomedical Engineering

The Nano Group, Inc., Farmington, Connecticut, USA

Ocean organisms employ engineering strategies which enable them to maintain life functions such as buoyancy and locomotion in a growing, self-repairing body. This book explores the possibilities of using these engineering feats in the human world. Each chapter presents a particular engineering problem and then looks to the organisms of the ocean for solutions. The book offers case studies that demonstrate how natural solutions can be applied to some specific engineering challenges, both terrestrial and oceanic. The text encourages engineers to explore new ideas, rather than mimic them.

A blend of information from the Biomedical Engineering Handbook and new material, this book draws on the experience of experts from countries such as Iran, Cuba, South Africa, UK, Canada, China, India, and Russia. Reflecting the increasing importance of nanomedicine and biotechnology, this material covers topics such as biomimicry, stem cells, optical togs, and nanocoatings for medical implantable devices. The book also provides insights into the food and cosmetics industries, as well as cardiac diagnosis, batteries, drug delivery, photonics, and DNA building blocks. It also discusses protein devices, quantum dots, bioanalysis, optics, nanomedicine, personalized medicine, and the business of emerging bionanotech companies.

Catalog no. K11710, ISBN: 978-1-4398-3762-7 February 2013, 7 x 10, 400 pp. Suggested Price: $169.95 / £108.00

Catalog no. K10254, ISBN: 978-1-4398-0463-6 August 2011, 7 x 10, 583 pp. Suggested Price: $119.95 / £76.00 Also available as an eBook

Biomimetics

Biosensors and Molecular Technologies for Cancer Diagnostics

Nature-Based Innovation

Edited by

Edited by

University of Maryland, College Park, USA

Yoseph Bar-Cohen JPL/Caltech, Pasadena, California, USA

18

David E. Reisner

University of Bath, United Kingdom

A review of the current state of the art of biomimetics, this book documents key biological solutions that provide a model for innovations in engineering and science. Leading experts explore a wide range of topics, including artificial senses and organs; mimicry at the cell–materials interface; modeling of plant cell wall architecture; biomimetic composites; artificial muscles; biomimetic optics; and the mimicking of birds, insects, and marine biology. The book also discusses applications of biomimetics in manufacturing, products, medicine, and robotics; biologically inspired design as a tool for interdisciplinary education; and the biomimetic process in artistic creation. Catalog no. K11566, ISBN: 978-1-4398-3476-3 September 2011, 7 x 10, 788 pp. Suggested Price: $167.95 / £107.00 Also available as an eBook

Keith E. Herold Avraham Rasooly National Cancer Institute, Rockville, Maryland, USA and the FDA Center for Devices and Radiological Health, Silver Spring, Maryland, USA Series in Sensors

Bridging the gap between research and clinical application, this volume explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements of biosensors and their applications in detection and diagnostics. Making biosensor technology more accessible to molecular biologists, oncologists, pathologists, and engineers, the book advances the integration of this technology into mainstream clinical practice. Catalog no. K11937, ISBN: 978-1-4398-4165-5 May 2012, 7 x 10, 844 pp. Suggested Price: $169.95 / £108.00 Also available as an eBook

Biosensors Based on Nanomaterials and Nanodevices Bionanotechnology

Edited by

Concepts & Applications

Kansas State University, Manhattan, USA

Maheshwar Sharon IIT Bombay (retired), Birla College, Nanotechnology Research Center, India

Madhuri Sharon Monad Nanotech Pvt. Limited, Mumbai, India

Highlighting the human applications of the science, this volume discusses the fundamental concepts and underlying science of bionanotechnology, and the bionanomachines that result from research into this exciting new field. Distilling the author’s research and groundbreaking original experimentation, chapters cover bionanomachines and their use with and manipulation of DNA, RNA, proteins, carbohydrates and lipids. Well-documented and authoritative, this book offers students and scientists alike the foundational information required to advance this powerful and potentially life-altering field. Catalog no. K12393, ISBN: 978-1-4398-5214-9 May 2012, 6 x 9, 300 pp. Suggested Price: $79.95 / £49.99

Jun Li Nianqiang Wu West Virginia University, Morgantown, USA Series: Nanomaterials and their Applications

This book is a useful source for readers for beginners to expert researchers to get a quick overview of exciting potentials and critical challenges of emerging biosensors based on nanomaterials and nanodevices for future health monitoring, disease diagnosis, and therapeutic treatments. The book highlights developments in biosensors based on nanomaterials and nanodevices in about 10 to 15 chapters on focused topics. It is intended to serve as a comprehensive source for researchers, graduate students, and industrial engineers in this area, with the emphasis on the unique signal transducing mechanisms and potential applications of nanoscale biosensors. Catalog no. K15174, ISBN: 978-1-4665-5151-0 June 2013, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

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Biosignal Processing Principles and Practices

Computer Vision

Edited by

From Surfaces to 3D Objects

Hualou Liang

Edited by

Drexel University, Philadephia, Pennsylvania, USA

Joseph D. Bronzino

Christopher W. Tyler

Donald R. Peterson University of Connecticut, Farmington, USA

This book provides state-of-the-art coverage of contemporary methods in biosignal processing, with emphasis on brain signal analysis. The topics covered in this book reflect an ongoing evolution in biosignal processing. As biomedical datasets grow larger and more complicated, emerging signal processing methods to analyze and interpret these data have gained in importance. This book discusses the process for biosignal analysis and stimulates new ideas and opportunities for developing cutting-edge computational methods for biosignal processing, which will in turn accelerate laboratory discoveries into treatments for patients. Catalog no. K13271, ISBN: 978-1-4398-7143-0 October 2012, 7 x 10, 202 pp. Suggested Price: $99.95 / £63.99

Computer Vision is the first book to take a full approach to the challenging issue of veridical 3D object representation. It introduces mathematical and conceptual advances that offer an unprecedented framework for analyzing the complex scene structure of the world. Leading theorists cover full 3D scene reconstruction, instead of the simplistic 2D planar algorithms employed in the past. They explore cutting-edge research on computational algorithms for scene analysis and present an integrated, complementary treatment of neural, behavioral, mathematical, and computational approaches. The text includes numerous graphics of complex processes, with many in color. Catalog no. K10887, ISBN: 978-1-4398-1712-4 January 2011, 6-1/8 x 9-1/4, 292 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

Also available as an eBook

The Clinical Nanomedicine Handbook Sara Brenner State University of New York and University at Albany, New York

This is the first clinically oriented, high quality, comprehensive volume detailing the latest major worldwide developments in nanomedicine. Outlined by specialty area, this book highlights major advances in medical applications of nanotechnology in a way that is structurally, linguistically, and logically aligned with today’s practicing clinicians, medical researchers, and scientists. The text integrates current research, translational applications, and future projections to provide a comprehensive roadmap of the state of the science. Topics covered include radiology, cardiology, oncology, ophthalmology, surgery, dermatology, medical genetics, dentistry, and neurology. Catalog no. K11567, ISBN: 978-1-4398-3478-7 March 2013, 7 x 10, 1000 pp. Suggested Price: $199.95 / £127.00 Also available as an eBook

Design Controls for the Medical Device Industry Marie B. Teixeira and Richard Bradley Design Controls for the Medical Device Industry provides real-world examples, strategies, and templates for the implementation of effective design control programs that meet ISO 9000 and FDA QSR standards and regulations. It also offers product development models for the production of safe, durable, and cost-efficient medical devices and systems. The book details procedures utilized by leading companies to successfully meet FDA and end-user requirements, manufacture high-quality products, and improve and generate profit. It presents blueprints for the application, evaluation, and refinement of quality assurance and performance practices, from product launch through engineering and assembly. Catalog no. DK5666, ISBN: 978-0-8247-0830-6 September 2002, 6 x 9, 254 pp. Suggested Price: $209.95 / £134.00 Also available as an eBook

Textbook

Computer Access for People with Disabilities A Human Factors Approach

Design of Biomedical Devices and Systems Second Edition Paul H. King Vanderbilt University, Nashville, Tennessee, USA

Richard C. Simpson University of Pittsburgh, Pennsylvania, USA Rehabilitation Science in Practice Series

Incorporating Compass Computer Access Assessment software, this book provides the information clinicians need to know in order to provide effective alternative computer access solutions to individuals with disabilities. It presents technology for individuals with visual impairments, cognitive impairments, and for older adults. Using case studies, the author provides in-class activities for students to record and compare performance with different computer access devices and configurations. The text covers text entry devices, pointing devices, switch access, automatic speech recognition, and web accessibility.

Biomedical Engineering

Smith-Kettlewell Eye Research Institute, San Francisco, California, USA

Simsbury, Connecticut, USA

Richard C. Fries ISORel, Inc., Fitchburg, Wisconsin, USA

The second edition of a bestseller, this book provides a comprehensive overview of biomedical device and system design—including topics related to databases, process analysis, and device improvement—from a strong design perspective. It covers all aspects of design that must be considered for complex biomedical projects. This second edition features information on device definition and reliability, as well as testing and hardware verification and each chapter has been updated to reflect the latest advances in the field. A solutions manual is available upon qualifying course adoption

Catalog no. K15286, ISBN: 978-1-4665-5371-2 January 2013, 6-1/8 x 9-1/4, 336 pp. Suggested Price: $99.95 / £63.99

Catalog no. 61798, ISBN: 978-1-4200-6179-6 August 2008, 7 x 10, 424 pp. Suggested Price: $129.95 / £82.99

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19


Diagnostic Endoscopy Edited by

Biomedical Engineering 20

Feedback Control in Systems Biology

Haishan Zeng

Carlo Cosentino

BC Cancer Research Centre, Vancouver, British Columbia, Canada

Declan Bates

University of Catanzaro, Italy

Series in Medical Physics and Biomedical Engineering

University of Exeter, UK

Combining a professional development course on diagnostic endoscopy from SPIE (the international society advancing light-based research) and the authors’ graduate course on biomedical optics, this work is written for researchers in medical optics and biomedical engineering as well as graduate medical optics students. It uses extensive examples/case studies to familiarize readers with the basics of endoscopic optics, the pros and cons of white light endoscopy and fluorescence endoscopy for diagnostic applications, and various microscopic endoscopy imaging modalities. It covers basic optics, details of design and biomedical uses, as well as microscopic endoscopy, and endoscopic spectroscopy.

Filling the need for a text on control theory for systems biologists, this selfcontained, easy-to-follow book explains how feedback control concepts can be applied to systems biology. Each chapter introduces key topics and case studies that explore applications in cellular and molecular biology. The authors cover tools and techniques for the analysis of linear and nonlinear systems, negative and positive feedback, robustness analysis methods, techniques for the reverseengineering of biological interaction networks, and the analysis of stochastic biological control systems. A valuable reference, this text offers a sound starting point for scientists entering this fascinating and rapidly developing field.

Catalog no. C8346, ISBN: 978-1-4200-8346-0 May 2013, 6-1/8 x 9-1/4, 288 pp. Suggested Price: $99.95 / £63.99

Catalog no. K10870, ISBN: 978-1-4398-1690-5 October 2011, 6-1/8 x 9-1/4, 296 pp. Suggested Price: $93.95 / £59.99

Also available as an eBook

Also available as an eBook

From Bioimaging to Biosensors Electromagnetic Fields in Biological Systems

Noble Metal Nanoparticles in Biodetection Edited by

Chau Lai-Kwan

Edited by

National Chung Cheng University, Chia-Yi, Taiwan

James C. Lin

Huan-Tsung Chang

University of Illinois at Chicago, USA

National Taiwan University, Taipei

Spanning static fields to terahertz waves, this volume explores the range of consequences electromagnetic fields have on the human body. Topics discussed include essential interactions and field coupling phenomena; electric field interactions in cells, focusing on ultrashort, pulsed high-intensity fields; dosimetry or coupling of ELF fields into biological systems; and the historical developments and recent trends in numerical dosimetry. It also discusses mobile communication devices and the dosimetry of RF radiation into the human body, exposure and dosimetry associated with MRI and spectroscopy, and available data on the interaction of terahertz radiation with biological tissues, cells, organelles, and molecules.

This book provides a comprehensive overview of the use of noble metal nanoparticles for bioimaging and biosensing. It starts with a review on the synthesis, characterization, optical properties, and bioconjugation of noble metal nanoparticles, followed by introduction of various biodetection techniques based on noble metal nanoparticles. In between these topics, microfabrication of biosensing chips and the use of microfluidics to enhance biosensing performance are discussed.

Catalog no. K12740, ISBN: 978-1-4398-5999-5 October 2011, 6-1/8 x 9-1/4, 458 pp. Suggested Price: $157.95 / £101.00

Also available as an eBook

Also available as an eBook

Textbook

Catalog no. N10569, ISBN: 978-981-4267-24-3 October 2012, 6 x 9, 322 pp. Suggested Price: $149.95 / £95.00

From MEMS to Bio-MEMS and Bio-NEMS Encyclopaedia of Medical Physics Edited by

Slavik Tabakov, Franco Milano, Sven-Erik Strand, Cornelius Lewis, Perry Sprawls Co-published by the EMITEL consortium and supported by the IOMP, this allencompassing reference contains roughly 3,500 cross-referenced entries relating to medical physics and associated technologies. Featuring over 100 contributors who are specialists in their respective areas, the encyclopedia describes new and existing methods and equipment in medical physics at a level accessible to graduate students. It covers x-ray diagnostic radiology, MRI, nuclear medicine, radiation protection, radiotherapy, and ultrasound imaging. Each article includes references and further reading, with many also incorporating images, graphs, formulas, and examples. Catalog no. K12085, ISBN: 978-1-4398-4652-0 December 2012, 8-1/2 x 11, 927 pp. Suggested Price: $595.00 / £379.00

Third Edition, Manufacturing Techniques and Applications Marc J. Madou University of California, Irvine, USA

This book details manufacturing techniques applicable to bio-nanotechnology. After reviewing MEMS techniques, materials, and modeling, the author covers nanofabrication, genetically engineered proteins, artificial cells, nanochemistry, and self-assembly. He also discusses scaling laws in MEMS and NEMS, actuators, fluidics, and power and brains in miniature devices. He concludes with coverage of various MEMS and NEMS applications. This color text offers end-of-chapter problems, worked examples throughout, extensive references, and PowerPoint slides for download. A solutions manual, instructors manual, and figure sides are available upon qualifying course adoption

Catalog no. 5516X, ISBN: 978-1-4200-5516-0 June 2011, 8-1/2 x 11, 650 pp. Suggested Price: $104.95 / £66.99 Also available as an eBook

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Textbook

Fundamentals of Biomechanics

Handbook of Intelligent Scaffold for Tissue Engineering and Regenerative Medicine Edited by

University of Cincinnati, Ohio

Chonbuk National University, Jeonju, North Korea

This textbook provides a comprehensive survey of how the principles of mechanics are applied to human systems and organs. After a review of terminology, a summary of human anatomy, and a presentation of anthropometric data, the text discusses methods for biomechanical analyses including essential mathematics, mechanics, and modeling techniques. It then covers tissue biomechanics, kinematics and dynamics of human body models, and applications such as lifting, walking, swimming, and accident victim simulation. Each chapter contains reference lists for more in-depth study and problems sets with solutions. A solutions manual and figure slides are available upon qualifying course adoption

Providing detailed knowledge about fullerene nanowhiskers and the related lowdimensional fullerene nanomaterials, this book introduces tubular nanofibers made of fullerenes, “fullerene nanotubes,” as well as the single crystalline thin film made of C60, called “fullerene nanosheet.” It is the first publication featuring the fullerene nanowhiskers made of C60, C70, and C60 derivatives and so forth. It demonstrates the synthetic method (liquid–liquid interfacial precipitation method) and the physical and chemical properties such as electrical, mechanical, optical, magnetic, thermodynamic, and surface properties for the fullerene nanowhiskers, including their electronic device application.

Catalog no. K14776, ISBN: 978-1-4665-1037-1 April 2013, 6-1/8 x 9-1/4, 512 pp. Suggested Price: $99.95 / £63.99

Catalog no. N10464, ISBN: 978-981-4267-85-4 February 2012, 6 x 9, 974 pp. Suggested Price: $499.95 / £318.00 Also available as an eBook

Healthcare Sensor Networks Challenges Toward Practical Implementation

Genetic Engineering Recent Developments in Applications

Edited by

Edited by

Victoria University, Melbourne, Australia

Dana M. Santos

Daniel Tze Huei Lai and Rezaul Begg Marimuthu Palaniswami

Binghamton University, New York, USA

University of Melbourne, Parkville, Victoria, Australia

A common tool in both research and agriculture, genetic engineering involves the direct manipulation of genes. Today’s areas of medical research include genetic engineering to produce vaccines against disease, pharmaceutical development, and the treatment of disease. In agriculture, genetic engineering is used to modify crops and domestic animals to increase their yields, aid in production, and enhance nutritive aspects. This important book covers new research and studies in genetic engineering in the areas of medicine and agriculture. Catalog no. N10630, ISBN: 978-1-926692-67-8 April 2011, 6-1/8 x 9-1/4, 336 pp. Suggested Price: $149.95 / £95.00

From network deployment to secure monitoring, this book addresses the latest developments in healthcare sensor networks—medical monitoring devices implanted on the body or in the surrounding infrastructure. The text discusses fundamental concepts and provides examples of clinical applications, including sensors to monitor physical activity in children and wearable gait assistants for people with Parkinson’s. Each chapter details a separate challenge in design and implementation. Addressing topics ranging from sensor hardware and the demand for higher data bandwidth to portability and cost, the book highlights the key areas that require further research for HSNs to become a technological and commercially viable reality. Catalog no. K11159, ISBN: 978-1-4398-2181-7 September 2011, 6-1/8 x 9-1/4, 462 pp. Suggested Price: $157.95 / £101.00

Also available as an eBook

Also available as an eBook

Handbook of Biomedical Optics Edited by

David A. Boas

Heart Rate Variability (HRV) Signal Analysis

Harvard Medical School, Charlestown, Massachusetts, USA

Clinical Applications

Constantinos Pitris

Edited by

University of Cyprus, Nicosia

Markad V. Kamath and Adrian Upton

Nimmi Ramanujam Duke University, Durham, North Carolina, USA

Taking a broad yet detailed approach, this comprehensive handbook covers light-based diagnostic methodologies and light-mediated therapeutics as well as concepts and cutting-edge optical methods used in research and practice. Extensively illustrated, the book presents the theory and fundamentals, along with state-of-the-art applications. The expert contributors also discuss advantages and disadvantages of various techniques. After introducing the background principles of optics, light sources, and irradiation and basic tissue optics concepts, the book focuses on spectroscopic methods, tomographic imaging, microscopic imaging methods, molecular probe development, and phototherapy. Catalog no. 90364, ISBN: 978-1-4200-9036-9 June 2011, 8-1/2 x 11, 831 pp. Suggested Price: $157.95 / £101.00 Also available as an eBook

Biomedical Engineering

Gilson Khang

Ronald L. Huston

McMaster University, Hamilton, Ontario, Canada

Mari A. Watanabe St. Louis University, Missouri, USA

Written for graduate students and professionals dealing with heart rate variability (HRV), this cutting-edge reference reviews how minute variations in the beat-tobeat heart rate are regulated. It explores how these variations can be used as a window to understanding the central and peripheral mechanisms that modulate the autonomic nervous systems. Explaining how HRV is characterized through simple statistics and frequency analysis in both healthy human subjects and patients with a variety of diseases, the book provides examples for methods that require mathematical techniques. The authors cite a variety of real-life medical situations and offer extensive end-of-chapter references. Catalog no. K12259, ISBN: 978-1-4398-4980-4 October 2012, 7 x 10, 532 pp. Suggested Price: $149.95 / £95.00

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21


Image Processing Tensor Transform and Discrete Tomography with MATLAB® Artyom M. Grigoryan San Antonio, Texas, USA

Merughan M. Grigoryan Yerevan, Armenia

A Machine Learning Approach Edited by

R. Bharat Rao Siemens, Malvern, Pennsylvania, USA

Glenn Fung Siemens Medical Solutions, Madison, Wisconsin, USA

Romer Rosales

Biomedical Engineering

Focusing on mathematical methods in computer tomography, this book introduces novel approaches to help solve the problem of image reconstruction on the Cartesian lattice. Specifically, it discusses methods of image processing along parallel rays to more accurately reconstruct images from a finite number of projections and avoid overradiating the body during a CT scan. The book presents several new concepts and methods, including methods of transferring the geometry of rays from the plane to the Cartesian lattice, the point map of projections, the particle and its field function, and the statistical model of averaging. Catalog no. K14749, ISBN: 978-1-4665-0994-8 September 2012, 6-1/8 x 9-1/4, 466 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Chapman & Hall/CRC Data Mining and Knowledge Discovery Series

Focusing on several recent, novel machine learning automatic algorithms, this reference provides the first source on the use of machine learning methods in designing computer-aided diagnosis (CAD) systems. It proposes a framework for CAD problems, presents the technical issues involved when building classifiers, and provides the appropriate machine learning techniques to address these problems. The book also includes results and concrete examples for different diseases and imaging modalities. It provides a useful tool for researchers and students in the biomedical sciences and machine learning as well as for advanced courses on CAD and/or medical informatics. Catalog no. K11767, ISBN: 978-1-4398-3887-7 April 2013, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $89.95 / £54.99 Also available as an eBook

Textbook

Introduction to Biomedical Engineering Technology

Textbook

Second Edition

A Laboratory Course in Tissue Engineering

Laurence Street

Melissa Kurtis Micou

Rosedale, British Colombia, Canada

University of California, San Diego, USA

Thoroughly revised and updated, this second edition describes current technological devices, the physiological and anatomical basis of their function, their practical applications, and their common locations in hospitals. Written by an experienced biomedical engineering technologist, the text discusses tools and test equipment, examines the integration of equipment within the hospital system, and presents an overview of various kinds of hardware related to medical equipment. Throughout, this accessible book incorporates real-life examples of the work that biomedical engineering technologists do, preparing students for situations they will encounter on the job.

Dawn Kilkenny

Figure slides are available upon qualifying course adoption

22

Knowledge-Driven Medicine

Catalog no. K12781, ISBN: 978-1-4398-6058-8 October 2011, 7 x 10, 391 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

University of Toronto, Ontario, Canada

This book fills the need for a hands-on lab manual for tissue engineering instruction. Providing more than a semester’s worth of activities, it contains 15 standalone experiments based on both classic and modern approaches. Experiments encompass a set of widely applicable techniques: cell culture, microscopy, histology, immunohistochemistry, mechanical testing, soft lithography, and common biochemical assays. In addition to teaching these specific techniques, the experiments emphasize engineering analysis, mathematical modeling, and statistical experimental design. To minimize lab costs, experiments use equipment commonly found in labs equipped for tissue culture. A solutions manual is available upon qualifying course adoption. Figure slides are available upon qualifying course adoption

Catalog no. K13694, ISBN: 978-1-4398-7893-4 August 2012, 6-1/8 x 9-1/4, 304 pp., Soft Cover Suggested Price: $59.95 / £38.99 Also available as an eBook

Textbook

Introduction to Physics in Modern Medicine Second Edition Suzanne Amador Kane Haverford College, Pennsylvania, USA

Fully updated, this volume builds on the bestselling original to provide medical and physics students with an exploration of the physics-related applications found in state-of-the-art medical centers. Requiring very little physics, biology, or chemistry and keeping mathematics to a minimum, the application-dedicated chapters adhere to simple and self-contained qualitative explanations that make use of examples and illustrations. With an enhanced emphasis on digital imaging and computers in medicine, the text gives readers a fundamental understanding of the practical application of each. Supporting material includes an authormaintained website, and a solutions manual for qualifying instructors.

The Law of Regenerative Medicine and Tissue Engineering David S. Smith Pepper Hamilton LLP, Pittsburgh, Pennsylvania, USA

A solutions manual is available upon qualifying course adoption

Providing an overview of those legal and regulatory elements that can significantly impact the clinical introduction of cell- and tissue-based products, this timely volume is an important reference at both the federal and state level. It discusses guidelines for the numerous current clinical trials for complex tissue constructs and cell therapies and considers the development of strategies for building patent portfolios for the increasing number of companies commercializing skin substitutes, expanded cell populations for cartilage repair, and extracellular materials intended to enable remodeling or repair at the implementation site.

Catalog no. C9438, ISBN: 978-1-58488-943-4 April 2009, 6-1/8 x 9-1/4, 448 pp., Soft Cover Suggested Price: $62.95 / £39.99

Catalog no. K11293, ISBN: 978-1-4398-2650-8 June 2013, 6 x 9, 270 pp., Soft Cover Suggested Price: $59.95 / £38.99

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Learning Bio-Micro-Nanotechnology Mel I. Mendelson

Edited by

John G. Webster University of Wisconsin, Madison, USA

Loyola Marymount University, Los Angeles, California, USA

Series: Electrical Engineering Handbook

A primary text for undergraduate nanotechnology courses, this book is designed for students who lack a cross-disciplinary background and knowledge of micro- and nano-technology. Clearly and concisely written, it contains many examples, questions, and problems divided into three hierarchical learning skills: understanding, analyzing, and evaluating the concepts. The author attempts to break down the boundaries between biology, chemistry, physics, engineering, and ethics. He accomplishes this by co-mingling the vocabulary and concepts of these disciplines around bio-applications. Copiously illustrated, this new text leans heavily towards biological and biomedical applications and includes a comprehensive chapter on ethics.

Edited by one of the most renowned instrumentation experts in the world, this best-selling handbook contains nearly 150 contributions covering all aspects of the design and implementation of instrumentation. It describes the use of instruments and techniques for performing practical measurements in engineering, physics, chemistry, and the life sciences. Organized according to measurement problem, each section addresses the different ways of measuring a given variable. Each chapter presents basic information, a detailed mathematical treatment and advanced applications as well as expert opinions and areas for future study.

A solutions manual is available upon qualifying course adoption

Catalog no. 82035, ISBN: 978-1-4200-8203-6 November 2012, 7 x 10, 614 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Catalog no. 8347, ISBN: 978-0-8493-8347-2 December 1998, 7 x 10, 2630 pp. Suggested Price: $249.95 / £159.00

Measurement, Instrumentation, and Sensors Handbook Second Edition, Two-Volume Set Spatial, Time, and Mechanical Measurement

Biomedical Engineering

Textbook

The Measurement, Instrumentation and Sensors Handbook

Edited by

Mass Transport of Nanocarriers

John G. Webster

Edited by

Halit Eren

Rita Elena Serda University of Texas Health Science Center, Houston, USA

This book describes barriers from the macro to the nanoscale, starting with endothelial and mucosal barriers, and ending with cellular organelles. Experimental approaches to track nanoparticles in vitro and in vivo are presented, as well as the ability to tailor-make nanoparticles for specific functions. Several model types of nanoparticles are presented, as well the impact of particle attributes on biological transport. Catalog no. N10575, ISBN: 978-981-4364-41-6 December 2012, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

University of Wisconsin, Madison, USA Curtin University, Bentley, Australia Series: Electrical Engineering Handbook

Edited by one of the most renowned instrumentation experts in the world, this bestselling handbook contains nearly 150 contributors covering all aspects of the design and implementation of instrumentation. It describes the use of instruments and techniques for performing practical measurements in engineering, physics, chemistry, and the life sciences. Organized according to measurement problem, each section addresses the different ways of making a measurement for a given variable. Each chapter is updated and presents basic information, a detailed mathematical treatment, advanced applications, and areas for future studies. Catalog no. K12205, ISBN: 978-1-4398-4883-8 May 2013, 7 x 10, 2700 pp. Suggested Price: $249.95 / £159.00 Also available as an eBook

Mechanics of Cellular Bone Remodeling

Measurement, Instrumentation, and Sensors Handbook

Coupled Thermal, Electrical, and Mechanical Field Effects

Second Edition, Electromagnetic, Optical, Radiation, Chemical, and Biomedical Measurement

Qing-Hua Qin

Catalog no. K12210, ISBN: 978-1-4398-4891-3 May 2013, 7 x 10, 1250 pp. Suggested Price: $149.95 / £95.00

Australian National University, Acton

This is a unique reference that will appeal to the biomedical engineering community and individuals pursuing data relative to bone modeling, therapeutic design and the responses of bone to orthopedic therapies and prostheses. The book systematically discusses the bone remodeling process at both macro- and cellular level, providing derivations of the basic equations. It provides numerical simulations to model bone mechanics and dynamics during the remodeling process, and covers the response of bone materials to coupled thermo-magnetoelectro-elastic fields.

Also available as an eBook

Measurement, Instrumentation, and Sensors Handbook Second Edition, Spatial, Time, and Mechanical Measurement

Catalog no. K16026, ISBN: 978-1-4665-6416-9 January 2013, 6-1/8 x 9-1/4, 304 pp. Suggested Price: $139.95 / £89.00

Catalog no. K12208, ISBN: 978-1-4398-4888-3 May 2013, 7 x 10, 1250 pp. Suggested Price: $149.95 / £95.00

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Also available as an eBook

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23


Medical Instruments and Devices Principles and Practices Edited by

Mechanobiology Handbook Edited by

The College of New Jersey, Ewing, USA

Joseph D. Bronzino

Jiro Nagatomi Clemson University, South Carolina, USA

Biomedical Engineering 24

Steven Schreiner

Mechanobiology examines effects of mechanical force stimuli on cellular biological functions. At appropriate levels, mechanical stimuli are necessary for growth and maintenance of healthy tissues and organs. The past two decades have seen a dramatic increase in the level of research in mechanobiology. Collecting the cutting-edge research findings from a diverse range of scientists, this volume presents basic materials in mechanics and cell biology. The book is an appropriate reference for those new to the field and is designed to stimulate new ways of thinking in current mechanobiology researchers.

Simsbury, Connecticut, USA

Donald R. Peterson University of Connecticut, Farmington, USA

Catalog no. K13272, ISBN: 978-1-4398-7145-4 April 2013, 7 x 10, 400 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Catalog no. 91212, ISBN: 978-1-4200-9121-2 March 2011, 7 x 10, 563 pp. Suggested Price: $179.95 / £115.00 Also available as an eBook

The Medical Device R&D Handbook Second Edition

Medical Nanotechnology and Nanomedicine

Edited by

Harry F. Tibbals

Theodore R. Kucklick

University of Texas Southwestern Medical Center, Dallas, USA

TRKD Medical Devices, Los Gatos, California, USA

Series: Perspectives in Nanotechnology

Written for medical device designers, biomedical engineering students, physician entrepreneurs, and medical device entrepreneurs, this reference explains the basics on how to prototype and develop a medical device. It discusses the basics of plastics, adhesives, medical needles, and rapid prototyping as well as tips and tools to save time and money. This updated and expanded second edition includes practical advice and interviews from key opinion leaders and pioneers in the field. Extensive references at the end of each chapter enhance additional study.

This accessible guide reviews advances in nanoscience and nanotechnology and considers their applications in medicine. Providing an introduction to both the science and the infrastructure required to support these advances, this volume is written for non-experts, which can include medical researchers and clinicians, as well as those concerned with business aspects, regulation, and the administration of medical practices. The book provides a contextual background including history, definitions, and recent trends, and then investigates current and future nanotech applications in medicine and the biomedical sciences.

Catalog no. K10598, ISBN: 978-1-4398-1189-4 December 2012, 6-1/8 x 9-1/4, 504 pp. Suggested Price: $139.95 / £89.00

Catalog no. K10431, ISBN: 978-1-4398-0874-0 September 2010, 6-1/8 x 9-1/4, 527 pp., Soft Cover Suggested Price: $76.95 / £48.99

Also available as an eBook

Also available as an eBook

MEMS Packaging and Technology

Medical Equipment Management

Edited by

Keith Willson

Analog Devices, Bangalore, Karnataka, India

Imperial College, London, UK

Keith Ison and Slavik Tabakov

Vikas Choudhary Krzysztof Iniewski Redlen Technologies, Victoria, Canada

King’s College London, Strand, UK

Series: Devices, Circuits, and Systems

Series in Medical Physics and Biomedical Engineering

Offering insight into the problems and challenges of managing medical equipment within a healthcare system, this book helps readers develop an understanding of the business process and increase awareness of how maintenance of equipment is influenced by its design. It details the equipment management process: demonstration of need, funding, procurement, acceptance testing, asset register maintenance, user training and support, routine and breakdown maintenance, risk management, disinfection, incident reporting, device modifications and trials, and condemning and safe disposal of equipment.

Written by international experts, this book presents the latest research in the field of MEMS technology and the myriad applications that it has enabled. The text covers automotive, consumer, communication, and medical applications of MEMs. Some of the applications discussed include high-precision on-chip integrated oscillators for reference generations, gyroscopes in cameras for optical image stabilization, radio communication, bio-implantable kidneys, and mobile phones. Other chapters address MEMS packaging and MEMS resonators, providing a fundamental understanding to enable novel applications. There is also a chapter outlining the historical evolution of current nano micro systems.

Catalog no. K10003, ISBN: 978-1-4200-9958-4 April 2013, 6-1/8 x 9-1/4, 288 pp. Suggested Price: $79.95 / £49.99

Catalog no. K15054, ISBN: 978-1-4665-1581-9 March 2013, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00

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Nanocomposite Particles for Bio-Applications

Advances, Simulations and Applications

Materials and Bio-Interfaces

Edited by

Edited by

Toshio Fukuda and Carlos Tercero

Tito Trindade and Ana Luisa Daniel da Silva

Nagoya University, Japan

Universidade de Aveiro, Portugal

This book explains, using the example of endovascular intervention, the development of in vitro simulators for biomedical applications based on the scientific context in the robotics area and the explanation of the medical procedure to be simulated. It presents modeling methods for in vitro representation of human tissue and for representing tissue integrity during endovascular surgery simulation. Additionally, applications of this in vitro vasculature modeling technology are presented: flow control for human blood pressure simulation, computer fluid dynamics simulations using vasculature morphology, catheter insertion robot control and vasculature imaging based on magnetic trackers, and tailor-made scaffolds for blood vessel regeneration.

This book provides a concise state of the art of the synthesis and properties of nanocomposite particles with interest for diverse bio-applications. Contributions are mainly related to the chemical design of nanocomposite particles, their properties as well as their constituent materials, and the tailoring of biointerfaces that may be relevant to the fields of clinical diagnosis and drug delivery procedures, among other bio-applications.

Catalog no. N10580, ISBN: 978-981-4364-69-0 April 2012, 6 x 9, 300 pp. Suggested Price: $179.95 / £114.00

Catalog no. N10427, ISBN: 978-981-4267-78-6 August 2011, 6 x 9, 312 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Also available as an eBook

Nanobiomaterials Handbook Edited by

Nanomaterials for Electrochemical Sensing and Biosensing

Biomedical Engineering

Microsurgery

Edited by

Martin Pumera Nanyang Technological University, Singapore

Balaji Sitharaman State University of New York at Stony Brook, USA

Nanobiomaterials exhibit distinctive characteristics which make them suitable for a variety of biological applications. This volume provides a comprehensive overview of the field, offering a broad introduction for those new to the subject as well as a useful reference for advanced professionals. Analyzing major topics and disciplines in this arena, the book examines various synthesis and processing techniques important for developing nanobiomaterials, explores their unique nanoscopic physicochemical properties, discusses potential applications, and provides a detailed overview of the interactions between bionanomaterials/biological systems and the biocompatibility issues associated with bionanomaterials. Catalog no. 94661, ISBN: 978-1-4200-9466-4 June 2011, 7 x 10, 737 pp. Suggested Price: $179.95 / £115.00

Nanotechnology brings new possibilities for the development of sensors, biosensors, and novel electrochemical bioassays. Nanoscale materials have been extensively used in a wide variety of configurations—as electrode surfaces to promote electrochemical reaction, as “wires” to enzymes connecting their redox centers to electrode surface, as nanobarcodes for biomolecules, or as tags to amplify the signal of a biorecognition event. Nanomaterial-based electrochemical sensors have been used in many areas, including cancer diagnostics and the detection of infectious organisms. This book reviews important achievements in the field of nanomaterial-based electrochemical sensors and biosensors. Catalog no. N10702, ISBN: 978-981-4364-90-4 February 2013, 6 x 9, 250 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Also available as an eBook

Nanomedicine in Drug Delivery The Nanobiotechnology Handbook Edited by

Edited by

Arun Kumar and Eric Blough Marshall University, Huntington, West Virginia, USA

Heidi M. Mansour University of Kentucky, Lexington, USA

Yubing Xie University at Albany, State University of New York, USA

Adam Friedman Albert Einstein College of Medicine, Bronx, New York, USA

Offering a uniquely thorough overview of nanobiotechnology and its place in today’s advancements in applied science, this comprehensive survey combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science, bioanalysis, and bioenergy to address the full scope of current and future developments. World-class experts discuss the role of nanobiotechnology in bioanalysis, biomolecular nanotechnology, biosensors, and the use of nanotechnology in biofuels. Extensive references within each chapter facilitate further investigation into the field.

Focusing exclusively on the design, synthesis, and application of nanoparticles in a range of applications, this book illustrates how nanotechnology can tackle drug delivery challenges as well as addressing the uses of nanotechnology for both diagnosis and treatment of disease. It addresses nanoparticulate use in several biomedical applications including administration routes, controlled release, and MRI contrast enhancement. Drawing on contributions by leading experts in the field, it presents a wide range of clinical applications supported by examples and case studies.

Catalog no. K11758, ISBN: 978-1-4398-3869-3 November 2012, 7 x 10, 664 pp. Suggested Price: $169.95 / £108.00

Catalog no. K14612, ISBN: 978-1-4665-0616-9 May 2013, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $159.95 / £99.00

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25


Occupational Physiology Edited by

Nanomedicine

Karolinska Institutet, Stockholm, Sweden

A Soft Matter Perspective

Svend Erik Mathiassen

Edited by

Ewa Wigaeus Tornqvist

Dipanjan Pan

University of Gävle, Sweden School of Health Sciences, Jönköping, Sweden

Biomedical Engineering

This book provides a broad introduction to soft matters for nanomedicinal applications, with a deeper discussion of the individual modalities for molecular imaging. It includes a general introduction to the opportunities provided by this technology in chemistry, materials, biology, and nanomedicine. It is designed and written with the perspective that anyone, with or without previous knowledge of nanotechnology, would benefit. Catalog no. K16620, ISBN: 978-1-4665-7282-9 June 2013, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

A clear and accessible text on work physiology, this book focuses on important issues in the modern working life. Taking up some of today’s major public health problems— musculoskeletal disorders and stress—this book explains connections between work, well-being, and health according to up-to-date research in the field. It gives an orientation of useful methods for risk assessments and provides guidelines on arranging a good working life from the perspective of the working individual, the company, and the society as a whole. Catalog no. K13002, ISBN: 978-1-4398-6696-2 December 2011, 6-1/8 x 9-1/4, 309 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

Nanomedicine Principles and Practices Raj Bawa Bawa Biotechnology Consulting LLC, Ashburn, Virginia, USA

Joseph D. Bronzino Simsbury, Connecticut, USA

Donald R. Peterson University of Connecticut, Farmington, USA

Nanomedicine: Principles and Practices draws on material from the nanomedicine section of The Biomedical Engineering Handbook, Fourth Edition. Edited by Raj Bawa, Joseph D. Bronzino, and Donald A. Peterson, this reference brings together contributions by world-class experts in the field. Offering comprehensive treatment of the latest development and research being conducted in nanomedicine, this is a useful resource for practitioners, scientists, and researchers working in the areas of nanomedicine and nanobiotechnology as well as graduate students studying bioengineering and regenerative medicine.

26

Allan Toomingas

Catalog no. K13710, ISBN: 978-1-4398-7923-8 April 2013, 7 x 10, 300 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Optical Techniques in Regenerative Medicine Edited by

Stephen Morgan and Felicity R. Rose University of Nottingham, UK

Steve Matcher University of Sheffield, UK

This book is focused on the optical techniques that can be applied to regenerative medicine. It covers applications both in fundamental research and in the regenerative medicine industry for tissue engineering products. Each chapter gives an overview of a particular technique, its advantages and limitations in terms of structural and functional information provided, and examples of applications in regenerative medicine. This book provides a practical guide to the most appropriate techniques for a given application. It also offers a summary of major recent advances, such as use of machine vision for tracking growth of three-dimensional constructs in bioreactors and polarization sensitive optical coherence tomography for monitoring collagen alignment in cartilage growth. Catalog no. K12560, ISBN: 978-1-4398-5495-2 June 2013, 7 x 10, 400 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Textbook

Numerical Methods for Chemical Engineers Using Excel, VBA, and MATLAB Victor J. Law Tulane University, New Orleans, Louisiana, USA

Orthopaedic Biomechanics Edited by

Beth A. Winkelstein University of Pennsylvania, Philadelphia, USA

A solutions manual and figure slides are available upon qualifying course adoption

This book presents state-of-the-art developments of orthopedic biomechanics across tissues in the musculoskeletal system at all size scales and with direct relevance to engineering and clinical applications. Discussing the relationship between mechanical loading, function, and biological performance, it first reviews basic structure-function relationships for most major orthopaedic tissue types followed by the most-relevant structures of the body. It then addresses multiscale modeling and biologic considerations. It concludes with a look at applications of biomechanics, focusing on recent advances in theory, technology, and applied engineering approaches.

Catalog no. K16702, ISBN: 978-1-4665-7534-9 March 2013, 6-1/8 x 9-1/4, 208 pp. Suggested Price: $79.95 / £49.99

Catalog no. K12804, ISBN: 978-1-4398-6093-9 December 2012, 7 x 10, 648 pp. Suggested Price: $179.95 / £114.00

Also available as an eBook

Also available as an eBook

Since most practical engineering problems must be solved numerically, this text provides instruction on using numerical methods and Excel/VBA for chemical and biomolecular engineering problems. It also includes an introduction to MATLAB®. The book is the first to apply numerical methods specifically for chemical engineers in the Excel/VBA computing environment. All examples and exercises emphasize chemical and biomolecular engineering applications. Ancillaries are available with qualifying course adoption.

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Physics of Thermal Therapy

Textbook

Physical Chemistry for Engineering and Applied Sciences Frank R. Foulkes

Fundamentals and Clinical Applications Edited by

Eduardo Moros

A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. K15157, ISBN: 978-1-4665-1846-9 September 2012, 7 x 10, 703 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of thermal therapy. An overview of the fundamentals shows how use of controlled heat in medicine and biology involves electromagnetics, acoustics, thermodynamics, heat transfer, and imaging sciences. The book discusses challenges in the use of thermal energy on living tissues and explores genetic, cellular, and physiological responses that will help in combating cancer. It also highlights recent advances, including the treatment of solid tumors using image-guided thermal therapy, microbubbles, nanoparticles, and other cutting-edge techniques. Catalog no. K12209, ISBN: 978-1-4398-4890-6 December 2012, 8-1/2 x 11, 375 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Physics and Chemistry at Low Temperatures

The Physiology of Bioelectricity in Development, Tissue Regeneration, and Cancer

Edited by

Leonid Khriachtchev

Edited by

University of Helsinki, Finland

Tunneling reactions in chemistry are characterized by the low-temperature limit when the classical contribution is negligible. Many practical applications benefit from the lack of heat and have a deep physical basis. Interesting advantages of chemical synthesis at low temperatures have also been demonstrated. This book covers fundamental and practical aspects of the processes and experimental and theoretical methods used in the field. The chapters are written by leading scientists who have very strong experience in the selected topics, and many practical recommendations can be found in this book. Catalog no. N10426, ISBN: 978-981-4267-51-9 June 2011, 6 x 9, 536 pp. Suggested Price: $179.95 / £114.00 Also available as an eBook

Christine E. Pullar University of Leicester, UK

Exploring their role in the physiology of development and wound repair and pathophysiologies such as cancer, this book describes the importance of biological electric fields and their use as tools to influence tissue repair and regeneration. It also discusses the role of bioelectricity in cancer progression and the potential for bioelectricity-based therapies to target both the tumor and metastatic cancer cells. It demonstrates the role of bioelectricity in the directionality and speed of cell migration, proliferation, apoptosis, differentiation, and orientation. Catalog no. K11686, ISBN: 978-1-4398-3723-8 March 2011, 6 x 9, 342 pp. Suggested Price: $125.95 / £79.99 Also available as an eBook

Textbook

Physics for Diagnostic Radiology

Textbook

P. P. Dendy

Physiology, Biophysics, and Biomedical Engineering

Addenbrookes NHS Trust, Cambridge, UK

Edited by

B. Heaton

Andrew W. Wood

Third Edition

Aberdeen Radiation Protection Services, UK Series in Medical Physics and Biomedical Engineering

Swinburne University of Technology, Hawthorn, Victoria, Australia

Fully revised and updated, this bestselling text helps readers understand how various imaging techniques work. This edition includes chapters on PET and PACS as well as new material on digital receptors, radiation doses and risks to patients, and special radiographic techniques, including subtraction techniques and interventional radiology. It also emphasizes the differences between analogue and digital images and covers multi-slice CT and three-dimensional resolution, dual energy applications, and cone beam CT. Exercises, multiple choice questions, extensive references, and further reading aid in understanding.

Showing how biophysics and biomedical engineering have advanced modern medicine, this text provides a multidisciplinary understanding of biological phenomena and the instrumentation for monitoring these phenomena. It also explores the application of physics and engineering methods to medicine and biology. The book includes a range of numerical problems with worked solutions and offers MATLAB® code for advanced mathematical analysis of physiological and clinical monitoring systems.

Catalog no. 83155, ISBN: 978-1-4200-8315-6 August 2011, 7 x 10, 720 pp. Suggested Price: $79.95 / £49.99 Also available in soft cover and as an eBook

Biomedical Engineering

Moffitt Cancer Center, Tampa, Florida, USA

This book is the result of more than 30 years of teaching by the author of a onesemester course in physical chemistry to first-year students at the University of Toronto. The enrollment varied from 300 to 800 students per year over the years. The book is unique in that it provides the detailed development of the equations, which can be followed relatively easily even with only moderate mathematical skills and backgrounds. The book provides interesting and inspiring examples, as well as many problems and solutions.

Series in Medical Physics and Biomedical Engineering

A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. C6513, ISBN: 978-1-4200-6513-8 February 2012, 7 x 10, 782 pp. Suggested Price: $99.95 / £49.99 Also available as an eBook

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27


Pulmonary Nanomedicine Diagnostics, Imaging, and Therapeutics Edited by

Quantitative Understanding of Biosystems An Introduction to Biophysics

Neeraj Vij

Biomedical Engineering

Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Thomas M. Nordlund

This book provides an in-depth view on engineered nanomaterials (ENM) pulmonary effects and familiarizes readers with unique aspects of nanomaterial application and research, such as the effects of physicochemical properties on cellular uptake and toxicity. It focuses on the diagnostic and therapeutic utilities of nanomaterials in different lung diseases. The book discusses the novel applications of nanotechnology for the treatment of airway diseases such as asthma, allergy, chronic obstructive pulmonary diseases, cystic fibrosis, and lung cancer. It also discusses the strategies to overcome the pathophysiological and technical barriers as an attempt to synchronize the efforts of pulmonary biologists, chemists, and clinicians to develop novel nano-based diagnostics, imaging, and therapeutics tools for airway diseases.

This color text clearly describes the biological physics of macromolecules, subcellular structures, and whole cells, including interactions with light. It provides a hands-on understanding of the movement of microorganisms, reviews the necessary mathematics, discusses quantum mechanics in biosystems, and describes the transition from discreet random walks to continuum diffusive motion. The text also contains standard exercises, advanced problems, and miniprojects. An accompanying CD-ROM includes “active” versions of Excel graphs and diagrams from the text, along with links to mathematical and biological/biochemical source data.

Catalog no. N10499, ISBN: 978-981-4316-48-4 August 2012, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Quality and Safety in Radiotherapy Edited by

Todd Pawlicki, Peter B. Dunscombe, Arno J. Mundt, and Pierre Scalliet

28

Textbook

University of Alabama at Birmingham, USA

A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. 89772, ISBN: 978-1-4200-8972-1 March 2011, 8-1/2 x 11, 583 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

Red Blood Cell Aggregation Oguz Baskurt, Björn Neu, and Herbert J. Meiselman

The first text to focus solely on quality and safety in radiotherapy, this work encompasses not only traditional technically oriented quality assurance activities, but also general approaches regarding quality and safety. It includes contributions from experts both inside and outside the field to discuss both the processes and the people delivering the service. It includes discussions about Lean thinking, looks at reactive and prospective error management techniques, deals broadly with techniques to monitor, assure, and improve quality, and provides explicit details of quality control relating to equipment and patient-specific issues.

Red blood cell (RBC) aggregation, a normally occurring phenomenon and a major factor affecting blood rheology, is an important area of study within bioengineering. This volume is the first to comprehensively review the topic. It provides extensive coverage of the determinants and mechanisms of RBC aggregation. It also examines methods to measure and modify RBC aggregation and discusses comparative data in other mammals. Written by leading researchers, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.

Catalog no. K10241, ISBN: 978-1-4398-0436-0 December 2010, 8-1/2 x 11, 643 pp. Suggested Price: $145.95 / £93.00

Catalog no. K11945, ISBN: 978-1-4398-4180-8 September 2011, 6-1/8 x 9-1/4, 318 pp. Suggested Price: $139.95 / £89.00

Also available as an eBook

Also available as an eBook

Quality Control Training Manual Comprehensive Training Guide for API, Finished Pharmaceutical and Biotechnologies Laboratories Syed Imtiaz Haider

Reliable Design of Medical Devices, Third Edition

Julphar Gulf Pharmaceutical Industries, United Arab Emirates

Richard C. Fries

Syed Erfan Asif

ISORel, Inc., Fitchburg, Wisconsin, USA

A valuable tool for chemists and analysts working in quality control laboratories, this book provides technical solutions that fulfill training requirements and build skilled manpower. The text is written for practitioners in quality control laboratories, product development laboratories, and stability laboratories in pharmaceutical and bio-pharmaceutical manufacturing, along with students in pharmaceutical and biotechnology development. It includes chapters on various elements commonly used in quality control labs, with questions at the end to ensure understanding. It also includes training manuals, training log and a CDROM on various laboratory aspects.

Following in the footsteps of the bestselling second edition, this book shows you how to improve reliability in the design of advanced medical devices. The organization of the book now mirrors the typical product development process, from the concept, feasibility, and design phases through to verification and validation, design transfer and manufacturing, and field activity. Updated throughout, it reflects recent changes in the medical device field, including in software development and hardware test procedures. This practical, hands-on book guides you in preparing, designing, and testing medical devices more effectively.

Catalog no. K12268, ISBN: 978-1-4398-4994-1 February 2011, 6 x 9, 484 pp. Suggested Price: $146.95 / £94.00

Catalog no. K14218, ISBN: 978-1-4398-9491-0 September 2012, 6-1/8 x 9-1/4, 501 pp. Suggested Price: $179.95 / £114.00

Also available as an eBook

Also available as an eBook

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Textbook

Statistics for Biomedical Engineering

Targeted Muscle Reinnervation

Martyn R. Smith

Todd Kuiken and Aimee E. Schultz

Michigan Technological University, Houghton, USA

Rehabilitation Institute of Chicago, Illinois, USA

Series: Biomedical Engineering

Series in Medical Physics and Biomedical Engineering

This text covers the statistical methods necessary to carry out work in biomedical engineering and human health research. Highly interdisciplinary, it incorporates aspects from biostatistics, engineering statistics and probability, quality assurance, and epidemiology. The text begins with hypothesis testing and the scientific method, moves on to various statistical tests and modeling, and concludes with statistical theorems and probability. Examples and case studies are employed extensively to highlight the use and misuse of the statistical techniques and their interpretation in the scientific literature.

This reference covers clinical and bioengineering aspects of muscle reinnervation, a popular new technique at the boundary of biomedical and rehabilitation engineering and neuroscience. With contributions from pioneers in the field, the book provides a review of muscle reinnervation from a biomedical engineering and clinical perspective. It describes neuroscience and other related neuroprosthetic techniques. A companion website offers a wide range of videos and multimedia material to aid in comprehension and application.

Catalog no. K14288, ISBN: 978-1-4398-9741-6 May 2013, 6-1/8 x 9-1/4, 350 pp. Suggested Price: $99.95 / £63.99

Catalog no. K12796, ISBN: 978-1-4398-6080-9 June 2013, 6-1/8 x 9-1/4, 288 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Stem Cell Engineering Principles and Practices University of California, Berkeley, USA

Tissue Engineering and Regenerative Medicine

Joseph D. Bronzino

A Nano Approach

Edited by

David Schaffer

Simsbury, Connecticut, USA

Biomedical Engineering

Edited by

Edited by

Donald R. Peterson University of Connecticut, Farmington, USA

Murugan Ramalingam, Pekka Vallittu, Ugo Ripamonti, and Wan-Ju Li

With contributions from pioneers and experts, this book provides a broad overview of the challenges of stem cell engineering. It discusses advances made during the last decade that have led to increasingly defined culture systems for growing human ES cells, starting from co-culture with feeder cells in the presence of serum to growth on synthetic substrates in defined medium. The book highlights recent advances in the understanding of the cellular and molecular composition of the hematopoietic stem cell niche, as well as approaches to build upon this basic information to direct stem cell differentiation into blood cell lineages.

This book bridges the gap between nanotechnology and regenerative medicine to facilitate their transition from lab to the clinic. It compiles important aspects of basic science and fundamental principles for current nanotechnological innovations in biomaterials and cell, tissue, and organ engineering, and their clinical relevance, as well as future trends in regenerative medicine. It is intended for a wide audience including students, researchers, professors, and industrial experts working in the fields of biomaterial science and engineering, nanoscience and nanotechnology, bioengineering, cell biology, biomedical sciences, tissue engineering, and nanomedicine.

Catalog no. K13309, ISBN: 978-1-4398-7204-8 November 2012, 7 x 10, 216 pp. Suggested Price: $99.95 / £63.99

Catalog no. K13868, ISBN: 978-1-4398-8185-9 September 2012, 6-1/8 x 9-1/4, 592 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

Also available as an eBook

Szycher’s Handbook of Polyurethanes Second Edition

Tissue Engineering

Edited by

Principles and Practices

Michael Szycher, Ph.D Sterling Biomedical, Inc., Lynnfield, Massachusetts

Johh P. Fisher, Antonios G. Mikos, Joseph D. Bronzino, and Donald R. Peterson

Written as a reference for polyurethane technologists and end users, raw materials suppliers, and students in the field, this second edition covers the technical advances in the field over the past ten years. Filled with tables, charts, and photographs, it includes new data on green polyurethanes, automotive applications, new coatings, new manufacturing equipment, new healthcare uses, and other topics. Individuals from all major polyurethane intermediate suppliers and equipment manufacturers contributed to this updated handbook, and discuss current products and provide a comprehensive list of product portfolios.

With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nonobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. It provides a very comprehensive overview of major research topics in tissue engineering.

Catalog no. K11811, ISBN: 978-1-4398-3958-4 July 2012, 7 x 10, 1144 pp. Suggested Price: $199.95 / £127.00

Catalog no. K13429, ISBN: 978-1-4398-7400-4 December 2012, 7 x 10, 768 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

29


Wireless Body Area Networks Transport Phenomena in Biomedical Engineering

Biomedical Engineering / Biomedical Imaging 30

Technology, Implementation, and Applications

Principles and Practices

Edited by

Edited by

Monash University, Victoria, Australia

Mehmet R. Yuce

Robert A. Peattie, Robert J. Fisher, Joseph D. Bronzino, and Donald R. Peterson

Jamil Khan

This book couples the concepts of transport phenomena with chemical reaction kinetics and thermodynamics to introduce the field of reaction engineering. This is essential information needed to design and control engineering devices, particularly flow reactor systems. Each chapter in this section is somewhat self-contained. Similar concepts are brought forth and reinforced through applications and discussions. However, to further enhance the benefits obtained by the reader, the book first examines some elementary concepts, the most relevant being control volume selection and flow reactors. It provides a comprehensive treatment with an overview of major research topics related to transport phenomena pertaining to biomedical engineering.

The book provides a comprehensive overview for the latest WBAN systems, technologies, and applications. The chapters of the book have been written by various specialists who are experts in their areas of research and practice. The book starts with the basic techniques involved in designing and building WBAN systems. It explains the deployment issues and then moves into the application areas of WBAN. The remaining chapters focus on the development of hardware, signal processing algorithms, and wireless communication and network design for wearable and implantable body sensors used in WBAN applications. The book also deals with the antenna design, propagation in and around the body, channel modeling, coexistence and power management issues, which are other critical design components for WBAN systems to achieve a successful hospital deployment.

Catalog no. K13460, ISBN: 978-1-4398-7462-2 November 2012, 7 x 10, 180 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Viral Nanoparticles

University of Newcastle, Callaghan, Australia

Catalog no. N10478, ISBN: 978-981-4316-71-2 December 2011, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Tools for Material Science and Biomedicine Case Western Reserve University, Cleveland, Ohio, USA

Adaptive Optics for Biological Imaging

Marianne Manchester

Edited by

University of California, San Diego, La Jolla, USA

Joel A Kubby

Edited by

Nicole F. Steinmetz

This book overviews the applications of viral nanoparticles (VNPs) in areas ranging from materials science to biomedicine. It summarizes the many different VNP building blocks and describes chemistries that allow one to attach, entrap, or display functionalities on VNPs. The book outlines the strategies for the construction of 1-, 2-, and 3-D arrays, highlights the achievements in utilizing VNPs as tools for novel biosensors and nanoelectronic devices, and describes efforts in designing VNPs for biomedical applications, including their use as gene delivery vectors, novel vaccines, imaging modalities, and applications in targeted therapeutics. Catalog no. N10424, ISBN: 978-981-4267-45-8 August 2011, 7 x 10, 284 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

University of California-Santa Cruz, USA

Written by an international team of leaders in the field, this comprehensive reference presents a complete overview of the core principles, state-of-the-art methods, and emerging applications of adaptive optics in biological imaging. It emphasizes the use of adaptive optics to correct wavefront aberrations caused by light propagation in biological samples. Accessible to readers without a background in optics, the book describes the fundamentals, components, and systems used in adaptive optics. It also covers optics systems as well as newer applications in this rapidly expanding field. Catalog no. K12282, ISBN: 978-1-4398-5018-3 April 2013, 7 x 10, 352 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Textbook

Webb’s Physics of Medical Imaging Second Edition Edited by

Textbook

Biomedical Signal and Image Processing Second Edition

M. A. Flower

Kayvan Najarian

Institute of Cancer Research/Royal Marsden NHS Foundation Trust, UK

Robert Splinter

Virginia Commonwealth University, Richmond, USA

Series in Medical Physics and Biomedical Engineering

University of North Carolina at Charlotte, USA

Since the publication of the best-selling first edition, the technology and clinical applications of medical imaging have changed significantly. Gathering these developments into one volume, this comprehensive second edition presents the basic physics, modern technology, and up-to-date examples of clinical application across all the modalities of medical imaging. It now covers state-ofthe-art detector technology and computer processing used in medical imaging. Along with many new examples and figures, this edition includes new chapters on medical image processing and multimodality imaging.

Written for senior-level and first-year graduate students in biomedical signal and image processing, this book describes fundamental signal and image processing techniques that are used to process biomedical information. The book also discusses application of these techniques in the processing of some of the main biomedical signals and images, such as EEG, ECG, MRI, and CT. New features of this edition include the technical updating of each chapter along with the addition of many more examples, the majority of which are MATLAB® based.

Catalog no. IP743, ISBN: 978-0-7503-0573-0 June 2012, 7 x 10, 864 pp. Suggested Price: $89.95 / £49.99

Catalog no. K13235, ISBN: 978-1-4398-7033-4 May 2012, 6-1/8 x 9-1/4, 411 pp. Suggested Price: $99.95 / £63.99

Also available as an eBook

Also available as an eBook

A solutions manual is available upon qualifying course adoption

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Physical and Clinical Aspects

Image Processing in Radiation Therapy

Edited by

Edited by

Jack Venselaar, Ali S. Meigooni, Dimos Baltas, and Peter J. Hoskin

Kristy Kay Brock

Brachytherapy delivers a highly localized dose to a target region using radionuclides implanted in or very near to the tumor. This book provides a complete overview of the field and covers related delivery modalities such as electronic brachytherapy. Along with exploring new clinical protocols, it discusses major advances under development, including imaging and robotics, and strategies for improved dosimetry, Monte Carlo-based dose calculation, and optimization. The first part of the text offers a detailed understanding of the underlying physics, design, and implementation of the techniques. The second part provides a practical guide for practitioners.

This book provides complete descriptions of the techniques involved in medical image processing, using sufficient descriptions and practical references. Chapters cover topics of deformable registration, segmentation, image reconstruction, and integration of these practices into the radiation therapy environment. The four sections provide an overview of the image segmentation and reconstruction techniques using image processing across all modalities, and applications of these approaches in radiation therapy. The book also addresses the applications of registration, segmentation, and image reconstruction for radiation therapy, including adaptive radiotherapy, monitoring and tracking of treatment delivery, quantifying accuracy, and visualizing results.

Catalog no. K11997, ISBN: 978-1-4398-4498-4 November 2012, 8-1/2 x 11, 535 pp. Suggested Price: $199.95 / £127.00 Also available as an eBook

University of Toronto, Ontario, Canada

Catalog no. K11476, ISBN: 978-1-4398-3017-8 April 2013, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Correction Techniques in Emission Tomography Edited by

Monte Carlo Calculations in Nuclear Medicine Second Edition Applications in Diagnostic Imaging

Mohammad Dawood, Xiaoyi Jiang, and Klaus Schäfers

Edited by

European Institute for Molecular Imaging, Münster, Germany

Lund University Hospital, Sweden, and Lund University, Sweden

Series in Medical Physics and Biomedical Engineering

Written by an interdisciplinary team of medical doctors, computer scientists, physicists, engineers, and mathematicians, this volume presents various correction methods used in emission tomography to generate and enhance images. It covers nuclear medicine imaging, hybrid emission tomography, and optical imaging. An important aspect of the book is on new and sophisticated motion correction techniques in PET imaging. The book also illustrates basic principles as well as recent advances, such as model-based iterative algorithms and 4D methods. Catalog no. K10659, ISBN: 978-1-4398-1298-3 April 2012, 6-1/8 x 9-1/4, 287 pp. Suggested Price: $119.95 / £76.99 Also available as an eBook

M. Ljungberg and S.-E. Strand M. A. King University of Massachusetts Medical Center, Worcester, USA Series in Medical Physics and Biomedical Engineering

From first principles to current computer applications, this book covers the applications of Monte Carlo calculations in nuclear medicine and critically reviews them from a diagnostic perspective. New chapters in this edition cover codes and applications in pre-clinical PET and SPECT. The book explains how Monte Carlo methods and software packages can be applied to evaluate scatter in SPECT and PET imaging, collimation, and image deterioration. A guide for researchers developing methods to improve image resolution, it also demonstrates how Monte Carlo techniques can be used to simulate complex imaging systems. Catalog no. K11910, ISBN: 978-1-4398-4109-9 November 2012, 6-1/8 x 9-1/4, 357 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

The Image Processing Handbook Sixth Edition

Monte Carlo Techniques in Radiation Therapy Edited by

Joao Seco

John C. Russ

Biomedical Imaging

Comprehensive Brachytherapy

Massachusetts General Hospital, Boston, USA

North Carolina State University, Raleigh, USA

Frank Verhaegen

This sixth edition explores the tools used to acquire, process, and analyze data contained in images, for a wide variety of scientific fields. Using new examples and diagrams, it presents new sections on selecting a camera with resolution appropriate for use on light microscopes, the ability of current cameras to capture raw images with high dynamic range, and imaging in more than two dimensions. The book also discusses Dmax for x-ray images and combining images with different exposure settings to further extend the dynamic range. New coverage also includes shape measurements and developments in image file searching.

Providing a detailed guide to the use and customization of Monte Carlo techniques in radiation therapy, this book covers the breadth of practical medical applications of Monte Carlo methods including the modeling of irradiation devices and issues specific to electron, photon, proto/particle beams, and brachytherapy. Beginning with the basics of the Monte Carlo method and the fundamental mathematical and technical aspects, it illustrates the utilization of Monte Carlo in treatment planning optimization, image guided radiotherapy, radiation dosimetry, and quality assurance.

Catalog no. K11875, ISBN: 978-1-4398-4045-0 April 2011, 7 x 10, 885 pp. Suggested Price: $179.95 / £115.00

Catalog no. K14687, ISBN: 978-1-4665-0792-0 March 2013, 8-1/2 x 11, 416 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

Also available as an eBook

Maastro Clinic, Maastricht, Netherlands

For more information and a complete list of titles, visit us at www.crcpress.com

31


Biomedical Imaging / Biotechnology 32

Quantifying Morphology and Physiology of the Human Body with MRI

Targeted Molecular Imaging

Edited by

Edited by

Tugan L. Muftuler

Michael J. Welch

Associate Professor of Neurosurgery, Medical College Wisconsin, Milwalkee, USA

William C. Eckelman

Washington University, Saint Louis, Missouri, USA

Series in Medical Physics and Biomedical Engineering

University of California, San Diego, La Jolla, USA

Although traditionally a qualitative technique, MRI can be used to gather quantitative information on the structure and function of the human body. While historically applied to neurophysiology, MRI is now routinely being used to explore other organs and structures, especially the heart and skeleton. This volume reviews various MRI techniques for obtaining quantitative and physiological information of the human body. It compares and contrasts several different applications of MR in quantitative research and on various body parts/ structures, including data acquisition, processing, and analysis/interpretation. The book also explores new and emerging techniques and modeling.

This work is a comprehensive account of state-of-the-art disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery. It includes examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases. The book is a valuable tool for readers involved with targeted molecular imaging, medicinal chemistry, pharmacology, radiology, and medical physics.

Catalog no. K12423, ISBN: 978-1-4398-5265-1 April 2013, 6-1/8 x 9-1/4, 568 pp. Suggested Price: $159.95 / £99.99

Catalog no. K11953, ISBN: 978-1-4398-4195-2 February 2012, 8-1/2 x 11, 388 pp. Suggested Price: $169.95 / £108.00 Also available as an eBook

Also available as an eBook

Second Harmonic Generation Imaging Edited by

Francesco S. Pavone Universita degli Studi di Firenze, Sesto Fiorentino, Italy

Paul J. Campagnola

Applied Optics Fundamentals and Device Applications

University of Connecticut, Farmington, USA

Nano, MOEMS, and Biotechnology

Series in Cellular and Clinical Imaging

Mark A. Mentzer

Second harmonic generation serves as the basis for a microscope imaging contrast mechanism that visualizes cell and tissue structure and function. This book provides a complete overview of the principles underlying this technique and its current applications, including use in molecular sensing. Covering practical issues related to instrumentation, the text examines which kinds of external labels to use. It also gives detailed reviews of the use of second harmonic generation in biomedical research, from imaging of cancer and skin disorders to self-assembled gels, holographic SHG imaging, and tissue engineering applications.

U.S. Army Research Laboratory, Aberdeen Proving Ground, Maryland, USA

Catalog no. K12222, ISBN: 978-1-4398-4914-9 April 2013, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Stereotactic Radiosurgery and Radiotherapy

Providing an interdisciplinary look at optics technology, this book investigates the connection between nanotechnology, MOEMS, and biotechnology. It covers fundamental relationships and system applications and includes design examples and numerous useful references. The author discusses emerging technologies augmented with MEMS, MOEMS, nanotechnology, biotechnology, fiber optic sensing, integrated optics, optical computing and signal processing, integrated optics, and electro-optics. He uses case studies to illustrate how emerging optics technologies are applied in the marketplace. Catalog no. K11430, ISBN: 978-1-4398-2906-6 May 2011, 6-1/8 x 9-1/4, 368 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Edited by

Stanley H. Benedict, Ph.D. UC Davis Comprehensive Cancer Center, Sacramento, California, USA

Brian D. Kavanagh University of Colorado, Denver, USA

David J. Schlesinger University of Virginia Health System, Charlottesville, USA

Detailing multi-modality image co-registration and radiobiology, this book discusses state-of-the-art strategies for patient simulation and immobilization, treatment planning, and dose calculation algorithms in stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT). It presents a comprehensive treatment of the field’s history, major technological developments, clinical status, and practical considerations. The three main sections of the book cover delivery systems, precision patient positioning and immobilization, and treatment planning and dosimetry. The final section gives an overview of clinical outcomes and future directions for the field. Catalog no. K11954, ISBN: 978-1-4398-4197-6 May 2013, 8-1/2 x 11, 350 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

Bioseparation Technology Neeraj Mishra and Akhilesh Dubey Ane Books, India

Designed for those with a background in engineering or biology, this text explores the fundamentals of the emerging field of bioseparation technology. It begins with an introduction to bioprocesses and provides focused chapters on cell disruption, filtration, centrifugation, adsorption, and extraction. The book also examines membrane separation processes, precipitation, chromatography, electrokinetic, and methods of separation as well as finishing operations and formulation. Catalog no. N10039, ISBN: 978-1-4398-0172-7 December 2012, 6-1/8 x 9-1/4, 300 pp., Soft Cover Suggested Price: $49.95 / £31.99

www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-561-994-0555 • +44 (0) 1235 400 524


Biodiesel and Value Added Products

Biotechnology of Fungal Genes

Edited by

Edited by

Faizal Bux

V. K. Gupta and M. Ayyachamy

Durban University of Technology, South Africa

National University of Ireland, Galway

The book gives an in-depth analysis of microalgal biology, ecology, biotechnology, and biofuel production capacity as well as a thorough discussion on the value added products that can be generated from diverse microalgae. It summarizes the state of the art in microalgal biotechnology research, from microalgal strain selection, microbiology, cultivation, harvesting, and processing. Contributors from the US, Africa, Asia, South America, and Europe cover microalgal physiology, biochemistry, ecology, molecular biology, and more.

This volume focuses on filamentous fungi and highlights the advances of the past decade, both in methodology and in the understanding of genomic organization and regulation of gene and pathway expression. The approaches and techniques of molecular biology enable us to ask and answer fundamental questions about many aspects of fungal biology, and open the way to the directed manipulation of fungal genetics. Moreover, this book describes the development and advancement of fungal genes and the ways in which these are being exploited in species of economic importance either in biotechnology or in biochemistry.

Catalog no. K15038, ISBN: 978-1-4665-1529-1 March 2013, 6-1/8 x 9-1/4, 304 pp. Suggested Price: $169.95 / £108.00 Also available as an eBook

Catalog no. N10536, ISBN: 978-1-57808-787-7 March 2012, 6 x 9, 400 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Textbook Textbook

Biotechnology Operations

Biotechnology Fundamentals

Principles and Practices

Firdos Alam Khan

Michael J. Roy

Manipal University, Dubai, UAE

University of Wisconsin-Madison, USA

This textbook discusses the fundamentals of biotechnology as well as the latest developments such as stem cell research, cloning, biofuel, transgenic plants, genetically modified food or crops, pharmacogenomics, nano-biotechnology. Incorporating extensive pedagogy into the content, the authors provide examples, end-of-chapter problems case studies, and laboratory tutorials. They include definitions, historical perspectives, time lines, and major discoveries along with the major segments of biotechnology, products, current research and development, career prospects, ethical issues, and future trends.

Applying the author’s experience teaching the subject and working in both industry and government, this book introduces key biotechnology developments and covers critical elements, such as project management, regulatory affairs, quality assurance, biomanufacturing, quality control, nonclinical safety testing, and clinical evaluation. The author discusses these subjects in relation to development planning, process and pathways, management of integrated projects, and the business and economic aspects of development. Using simple language and explanatory figures, it describes the functional areas that must be successfully integrated to safely and efficiently bring a biotechnology product to market.

A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. K11059, ISBN: 978-1-4398-2009-4 September 2011, 7 x 10, 608 pp. Suggested Price: $93.95 / £49.99 Also available as an eBook

A solutions manual and figure slides are available upon qualifying course adoption

Catalog no. K11486, ISBN: 978-1-4398-3027-7 March 2011, 6-1/8 x 9-1/4, 416 pp. Suggested Price: $104.95 / £66.99 Also available as an eBook

Biotechnology in Agriculture and Food Processing Opportunities and Challenges P. S. Panesar

Biotechnology

Biotechnological Applications of Microalgae

Boron Science New Technologies and Applications

Sant Longowal Institute of Engineering & Technology, India

Edited by

S.S. Marwaha

Narayan S. Hosmane

Punjab Biotechnology Incubator, India

Northern Illinois University, Dekalb, USA

An instructive and comprehensive overview of the use of biotechnology in various agriculture and food applications, this book discusses the current status of applications for improving quality and productivity of agriculture and food products. It discusses plant tissue culture techniques, genetic engineering in food ingredient production, bio-fertilizers, bio-pesticides, enzymes, genetically modified foods, etc. The book is divided into four parts: fundamental concepts, biotechnology in agriculture, biotechnology in food processing and biotechnological management of crop residues, and waste/by-products of agro industries.

As boron compounds find their way into an increasing number of applications and technologies, the field of boron chemistry research has grown substantially in recent years. However, finding reliable information on these advances has required searching across a vast amount of research literature. This book is the first of its kind to comprehensively cover the latest in boron science in a single source. The text addresses the application of boron in chemistry, industry, medicine, and pharmacology and explains its role in such problems as catalysis, hydroboration, superconductors, materials, and magnetic and nonmagnetic nanoparticles as well as in medical applications such as cancer therapy.

Catalog no. K14067, ISBN: 978-1-4398-8836-0 April 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $119.95 / £127.00

Catalog no. K11300, ISBN: 978-1-4398-2662-1 October 2011, 7 x 10, 878 pp. Suggested Price: $319.95 / £204.00

Also available as an eBook

Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

33


CMOS Nanoelectronics Innovative Devices, Architectures, and Applications Edited by

Nadine Collaert IMEC, Leuven, Belgium

Biotechnology

This book covers one of the most important device architectures that have been widely researched to extend the transistor scaling: FinFET. Starting with theory, the book discusses the advantages and the integration challenges of this device architecture. It addresses in detail the topics such as high-density fin patterning, gate stack design, and source/drain engineering, which have been considered challenges for the integration of FinFETs. The book also addresses circuit-related aspects, including the impact of variability on SRAM design, ESD design, and high-T operation. It discusses a new device concept: the junctionless nanowire FET. Catalog no. N10509, ISBN: 978-981-4364-02-7 September 2012, 6 x 9, 438 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Textbook

Colloids and Interfaces in Life Sciences and Bionanotechnology

Edited by

Dennis R. Heldman Heldman Associates, Mason, Ohio, USA

Matthew B. Wheeler University of Illinois, Urbana, USA

Dallas G. Hoover University of Delaware, Newark, USA

Focusing on the science and applications of molecular biology to agriculture and foods, this encyclopedia describes the new tools for use in the production of raw agricultural materials and the manufacturing of food products. Two hundred entries cover areas such as cloned animals, genetically modified and droughtresistant plants, biodiversity, and nutritionally enhanced foods. It explores media coverage of biotechnology, associated governmental regulations, consumer acceptance, and environmental issues. Illustrations and comprehensive references complement the text. This reference is also available in an online format. Catalog no. DK271X, ISBN: 978-0-8493-5027-6 July 2010, 8-1/2 x 11, 784 pp. Suggested Price: $441.00 / £281.00

Engineering Aspects of Food Biotechnology

Second Edition

Edited by

Willem Norde

University of Minho, Braga, Portugal

Wageningen University, The Netherlands, and University Medical Center Groningen, The Netherlands

34

Encyclopedia of Biotechnology in Agriculture and Food

This classroom-tested reference presents a concise introductory treatment of the physicochemical principles that determine interrelated colloidal and interfacial phenomena and their relevance to various life sciences. The book focuses on concepts that form the basis for understanding this behavior. Whether deciphering the spontaneous assembly of amphiphilic molecules or the intentional fouling of surfaces for the immobilization of cells in bioreactors, this book devotes special attention to reversible and soft colloids, and discusses the colloidal domain in a historical perspective, the size and distribution of particles, and electrokinetic phenomena, and more. Catalog no. K10890, ISBN: 978-1-4398-1718-6 June 2011, 6-1/8 x 9-1/4, 495 pp. Suggested Price: $134.95 / £39.99

Jose A. Teixeira and Antonio A. Vicente Series: Contemporary Food Engineering

Aimed at producing and improving food ingredients, developments in food biotechnology have focused on the fields of genetics and in enzyme- and cellbased biological processes. While the underlying science of these developments and applications has traditionally been well reported, there is a clear lack of information on the engineering aspects of such biotechnology-based food processes. This book provides a comprehensive review of these aspects, from the development of food processes and products to the most important unit operations. Catalog no. K14228, ISBN: 978-1-4398-9545-0 June 2013, 6-1/8 x 9-1/4, 375 pp. Suggested Price: $169.95 / £108.00 Also available as an eBook

Also available as an eBook

Gene Biotechnology Third Edition

Electroanalysis with Carbon Paste Electrodes Ivan Svancara, Kurt Kalcher, Alain Walcarius, and Karel Vytras Series: Analytical Chemistry

Because of their simple preparation and low expense, carbon pastes as well as carbon paste electrodes are widely used in a myriad of instrumental measurements. With an emphasis on practical applications, this book provides a comprehensive overview of carbon paste electrodes. The text offers a systematic presentation of the individual procedures that are used for determining hundreds of various substances. With a list of up-to-date references, this handy reference source includes specific experimental data and serves as a practical guide for experimental laboratory work. As a result, it is suitable for researchers as well as for students in the field. Catalog no. K11477, ISBN: 978-1-4398-3019-2 March 2012, 7 x 10, 666 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

William Wu Esperion Therapeutics, Inc., Ann Arbor, Michigan, USA

Helen H. Zhang, Michael J. Welsh, and Peter B. Kaufman University of Michigan, Ann Arbor, USA

The third edition of this popular reference covers a variety of techniques related to gene manipulation, including DNA isolation, preparation, screening, and analysis. Topics range from very basic methods to current and sophisticated technologies, including methodologies created and tested by the authors. The authors offer detailed, step-by-step explanations of protocols and helpful troubleshooting guides. The book also discusses approaches to grant funding and SiRNA technology. This edition features new techniques in every chapter, as well as several new chapters. An instructor’s manual is available upon qualifying course adoption. Figure slides are available upon qualifying course adoption

Catalog no. K12153, ISBN: 978-1-4398-4830-2 May 2011, 6-1/8 x 9-1/4, 575 pp. Suggested Price: $157.95 / £101.00 Also available as an eBook

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Genetics, Genomics and Breeding of Bananas Edited by

Vaal University of Technology, Vanderbijlpark, South Africa

Multifunctional Molecular Materials

George Ude

Edited by

Michael Pillay

Bowie State University, Maryland, USA

Lahcene Ouahab

Chittaranjan Kole

Laboratoire Sciences Chimiques de Rennes, France

Series: Genetics, Genomics and Breeding of Crop Plants

Musa is one of three genera in the family of Musaceae. Over 50 species of Musa exist, including bananas and plantains. This book assembles the latest information on the genomic research of this genus. A group of leading experts in Musa genetics, genomics, and breeding provide basic as well as advanced information for those interested in learning more about the banana genome. The accessible style is easily understood by students and researchers, making the book an ideal springboard for those looking to do expanded research into this crop. Catalog no. N10535, ISBN: 978-1-57808-788-4 March 2012, 6 x 9, 350 pp. Suggested Price: $119.95 / £76.99

This book provides a comprehensive overview on multifunctional molecular materials that involve coexistence or interplay or synergy between multiple physical properties focusing on electrical conductivity, magnetism, singlemolecule magnets behavior, chirality, spin crossover, and luminescence. The book’s coverage ranges from transition metals and lanthanide coordination complexes to genuine organic materials. The book also discusses some potentialities of applications of these materials in molecule-based devices. Catalog no. N10510, ISBN: 978-981-4364-29-4 December 2012, 6 x 9, 400 pp. Suggested Price: $249.95 / £159.00 Also available as an eBook

Also available as an eBook

Handbook of Analysis of Oligonucleotides and Related Products Edited by

Integrated Microsystems Electronics, Photonics, and Biotechnology

Biotechnology

Clemson University, South Carolina, USA

Edited by

Krzysztof Iniewski CMOS Emerging Technologies, Inc., Vancouver, British Columbia, Canada

Jose V. Bonilla Girindus America, Cincinnati, Ohio, USA

Series: Devices, Circuits, and Systems

G. Susan Srivatsa ElixinPharma, Encinitas, California, USA

Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. This volume is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among 30 leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. Catalog no. K11050, ISBN: 978-1-4398-1993-7 February 2011, 7 x 10, 511 pp. Suggested Price: $146.95 / £94.00

Written by experts from industry and academia around the world, this book focuses on electrical engineering and elaborates on how electrical circuits interface with biology, microfluidics, and photonics. Including only light math and physics, with greater focus on explanation, it covers integrated devices and other emerging structures required for future micro- and nanotechnologies. This material addresses physical and chemical sensing, imaging, smart actuation, and data fusion and management. Providing tables, figures, and equations to help illustrate concepts, the book’s contributors examine and explain the potential of emerging applications that are in integrated microsystems. Catalog no. K11637, ISBN: 978-1-4398-3620-0 October 2011, 7 x 10, 760 pp. Suggested Price: $167.95 / £107.00 Also available as an eBook

Also available as an eBook

Textbook

Introduction to Instrumentation in Life Sciences

Handbook of Biofunctional Surfaces

Prakash Singh Bisen Defense Research & Development Establishment, Gwalior, India

Anjana Sharma

Edited by

Rani Durgavati University, Jabalpur, India

Wolfgang Knoll Austrian Institute of Technology, Vienna

It is still the very beginning of generating a better understanding of what is needed to make an organism tolerate implants, to guarantee the bidirectional communication between microelectronic devices and living tissue, or to simply construct an interactive biocompatibility of surfaces in general. This book describes the design, synthesis, assembly and characterization, and the bio(medical) application of interfacial layers on solid substrates with molecularly or supra-molecularly controlled architectures. Experts in the field describe their contributions that have been developed in recent years.

Addressing aspects of instrumentation that hold the keys for cutting-edge research and innovative applications, this book is designed to serve a wide range of students and researchers in diversified fields of life sciences, including pharmacy, biotechnology, microbiology, biochemistry, and environmental sciences. The book is unique in its broad subject coverage, incorporating fundamental techniques as well as applications of modern molecular and proteomic tools that are the basis for state-of-the-art research. It includes well-illustrated diagrams to explain the principles and theories behind the instruments described. Figure slides are available upon qualifying course adoption

Catalog no. N10502, ISBN: 978-981-4316-63-7 September 2012, 6 x 9, 800 pp. Suggested Price: $500.00 / £318.00

Catalog no. K14893, ISBN: 978-1-4665-1240-5 September 2012, 7 x 10, 383 pp., Soft Cover Suggested Price: $79.95 / £49.99

Also available as an eBook

Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

35


Lactic Acid Bacteria Microbiological and Functional Aspects, Fourth Edition

Microspheres and Microcapsules in Biotechnology Design, Preparation and Applications

Biotechnology

Edited by

Edited by

Sampo Lahtinen, Arthur C. Ouwehand, Seppo Salminen, and Atte von Wright

Guanghui Ma and Zhi-Guo Su

Lactic acid-producing fermentation has long been used to improve perishable foods. Since the publication of the third edition of this volume, substantial progress has been made in a number of areas of research. The fourth edition covers all the basic and applied aspects of lactic acid bacteria and bifidobacteria. Topics discussed include revised taxonomy, new discoveries related to the mechanisms of lactic acid bacterial metabolism and function, an improved mechanistic understanding of probiotic functioning, applications in food and feed preparation, health properties of lactic acid bacteria, and the regulatory framework related to safety and efficacy.

This book focuses on the new microspheres and new microcapsules especially designed and prepared for the applications in biotechnology and biopharmaceuticals, including bio-reaction, bio-separation, bio-formulation, biodetection, and other new bio-applications. The book provides deep knowledge about the principle of design, preparation methods, and application results of new microsphere and microcapsules for each bio-application area; identifies problems that need to be studied further; and discusses future prospects.

Catalog no. K11662, ISBN: 978-1-4398-3677-4 December 2011, 7 x 10, 798 pp. Suggested Price: $199.95 / £127.00

Chinese Academy of Sciences, Beijing

Catalog no. N10573, ISBN: 978-981-4316-47-7 January 2013, 6 x 9, 1600 pp. Suggested Price: $500.00 / £318.00 Also available as an eBook

Also available as an eBook

Textbook

Methods for Studying Nucleic Acid/Drug Interactions

Molecular Motors in Bionanotechnology

Edited by

Keith Firman and James Youell

Meni Wanunu

University of Portsmouth, UK

Northeastern University, Boston, Massachusetts, USA

This book describes a wide range of molecular motors, ranging from chemical motors to biological motors, in a manner that updates, or reviews, both classification of the type of motor and the grouping into families. Many techniques have evolved to study and characterize molecular motors at the single-molecule level (e.g. use of molecular tweezer devices for single-molecule studies) and the reader is introduced to the concepts and benefits of each technique. In addition, the book looks at structural information and how this helps understand function and, finally, how some of these motors are being used or may be used in the future as part of a synthetic biology approach to building devices and sensors.

Yitzhak Tor University of California, San Diego, La Jolla, USA

36

This book describes emerging, non-conventional methods for probing the interactions of small molecules with nucleic acids as well as modern computational methods for assessment. By highlighting novel methods for nucleic acid/ligand interactions, the text presents drug developing companies with a survey of possible future techniques as well as their drawbacks and advantages with respect to common techniques. In addition, and perhaps more importantly, this book is designed to inspire young scientists to continue and advance these methods into fruition, especially in light of current capabilities for assay miniaturization and enhanced sensitivity using microfluidics and nanomaterials. Catalog no. K11829, ISBN: 978-1-4398-3973-7 December 2011, 6-1/8 x 9-1/4, 392 pp. Suggested Price: $119.95 / £76.99 Also available as an eBook

Catalog no. N10568, ISBN: 978-981-4267-02-1 August 2012, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

OMICS Applications in Biomedical, Agricultural, and Environmental Sciences Edited by

Micro and Nano Techniques for the Handling of Biological Samples

Debmalya Barh

Jaime Castillo-León, Winnie Edith Svendsen, and Maria Dimaki

Vasco Azevedo

Technical University of Denmark, Lyngby

The techniques and tools used to understand many biological problems must be able to handle biological material without damaging or altering its natural state. This book assesses various micro and nano techniques currently available to handle these materials. It shows how the techniques can effectively manipulate biological samples, and highlights the advantages and shortcomings of each. The authors also help readers understand how the manipulation tools work and how to determine the appropriate tool for their needs.

With contributions from active researchers, this book explores emerging fields such as metagenomics, cytomics, glycomics, miRNA and their various applications, demonstrating the real diversity of omics. It covers cutting-edge treatments such as toxicognenomics and its applications in assessment of environmental pollutants, applications of plant metabolomics, nutrigenomics and its therapeutic application, and microalgal omics and their applications in bio-fuel development. Next generation sequencing and omics technology for transgenic plant analysis is also included.

Catalog no. K11354, ISBN: 978-1-4398-2743-7 August 2011, 6-1/8 x 9-1/4, 255 pp. Suggested Price: $139.95 / £89.00

Catalog no. K15973, ISBN: 978-1-4665-6281-3 March 2013, 7 x 10, 752 pp. Suggested Price: $169.95 / £108.00

Also available as an eBook

Also available as an eBook

Institute of Integrative Omics and Applied Biotechnology, West Bengal, India

Vasudeo Zambare IIOAB, Nonakuri, West Bangal, India Universidade Federal of Minas Gerais, Belo Horizonte, Brasil

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OMICS Edited by

Debmalya Barh Institute of Integrative Omics and Applied Biotechnology, West Bengal, India

Kenneth Blum

Support Vector Machines and Their Application in Chemistry and Biotechnology Yizeng Liang, Qing-Song Xu, Hong-Dong Li, and Dong-Sheng Cao Central South University, Changsha, China

LifeGen, Inc., San Diego, California, USA

Margaret A. Madigan LifeGen, San Diego, California, USA

A reflection of the explosion of research and development in this field, this book explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. It collates recent developments in the field into a state-of-the-art framework for this discipline. A select panel of experts discusses their cutting-edge omics research and novel technologies, supplying a basic platform of methods and applications as well as a multi-omics approach to future endeavors in the fertile areas of omics research. Catalog no. K12277, ISBN: 978-1-4398-5008-4 November 2011, 7 x 10, 613 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

Presenting a clear bridge between theory and application, this volume provides a thorough description of the mechanism of support vector machines (SVMs) from the point of view of chemists and biologists. Topics discussed include elements and algorithms of support vector classification (SVC) machines and support vector regression machines (SVR), the kernel function for solving nonlinear problems, ensemble learning of SVMs, applications of SVMs to nearinfrared data, SVMs and quantitative structure-activity/property relationships (QSAR/QSPR), quality control of traditional Chinese medicine by means of the chromatography fingerprint technique, and the use of SVMS in exploring the biological data produced in OMICS study. Figure slides are available upon qualifying course adoption

Catalog no. K11127, ISBN: 978-1-4398-2127-5 May 2011, 6-1/8 x 9-1/4, 211 pp. Suggested Price: $125.95 / £79.99 Also available as an eBook

Personalized Medicine

Viral Diagnostics

Principles and Practices

Advances and Applications

Edited by

Edited by

Gualberto Ruano Hartford Hospital, Milford, Connecticut, USA

Joseph D. Bronzino

Robert S. Marks and Leslie Lobel Ben-Gurion University of the Negev, Beer Sheva, Israel

Amadou Sall

Simsbury, Connecticut, USA

Institut Pasteur de Dakar, Senegal

Donald R. Peterson Drawn from the Biomedical Engineering Handbook, Fourth Edition, this volume presents the work of world-class experts who discuss the latest research in personalized medicine. Some of the more sharply focused material in this handbook is not included in the larger volume, allowing for specialized study of the essential principles of this growing field. Clinicians, scientists, and researchers will find this an ideal resource for detailed study of the latest recommendations for tailoring choices to individual patient needs.

This book covers a spectrum of topics in the diagnostics and monitoring of viral ailments with an emphasis on the newer technologies in development such as optical fiber and electrochemical immunosensors, reverse genetics, luminescent molecular imprints of neutrophil biomarkers and many others. The contributors include experts from the fields of epidemiology, biotechnology, virology, industry, technologists, and clinics. The viruses range from influenza to emerging ebola virus. This text brings readers a composition of various aspects of the field while looking at the future after some introduction to the state of the art.

Catalog no. K13461, ISBN: 978-1-4398-7464-6 April 2013, 7 x 10, 300 pp. Suggested Price: $139.95 / £89.00

Catalog no. N10588, ISBN: 978-981-4364-43-0 November 2012, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

Also available as an eBook

University of Connecticut, Farmington, USA

Advances in Chromatography Stem Cells and Revascularization Therapies Edited by

Hyunjoon Kong and Lawrence B. Schook

Volume 49 Edited by

Eli Grushka The Hebrew University of Jerusalem, Israel

Nelu Grinberg

University of Illinois Urbana-Champaign, USA

Boehringer-Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA

Andrew J. Putnam

Series: Advances in Chromatography

University of California, Irvine, USA

In the last few decades, significant advancements in the biology and engineering of stem cells have enabled progress in their clinical application to revascularization therapies. Some strategies involve the mobilization of endogenous stem cell populations, and others employ cell transplantation. As a result, both techniques have benefited from multidisciplinary efforts to create biomaterials and other biomedical tools that can improve and control the fate of stem cells, and advance our understanding of them.

This venerable series has reported on the latest state-of-the-art developments in the field for the past four decades. Volume 49 continues the tradition of compiling the work of expert contributors who present cutting-edge reviews of methods and applications in chromatography. Highlights in this edition include: the hyphenation of liquid chromatography with mass spectrometry in order to determine oligonucleotide adducts as markers for cancer; glycoproteomics and the glycosylation of proteins, addressing biomarkers in different types of diseases; and chiral separation, an important area particularly in the pharmaceutical industry; and ion-pairing chromatography and analyte retention.

Catalog no. K10180, ISBN: 978-1-4398-0323-3 December 2011, 6-1/8 x 9-1/4, 342 pp. Suggested Price: $157.95 / £101.00

Catalog no. K11898, ISBN: 978-1-4398-4091-7 March 2011, 6-1/8 x 9-1/4, 461 pp. Suggested Price: $239.95 / £153.00

Also available as an eBook

Also available as an eBook

Series: Biotechnology and Bioprocessing

For more information and a complete list of titles, visit us at www.crcpress.com

Biotechnology / Methods & Instrumentation

Biomedical Perspectives and Applications

37


Advances in Chromatography Volume 50 Edited by

Eli Grushka Hebrew University of Jerusalem, Israel

Nelu Grinberg Boehringer-Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA Series: Advances in Chromatography

Methods & Instrumentation

For more than four decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 50, the series editors have invited established, well-known chemists from across the globe to offer cutting-edge reviews on their areas of expertise. The clear presentation of topics and vivid illustrations for which this series has become known makes the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill. Catalog no. K12720, ISBN: 978-1-4398-5844-8 January 2012, 6-1/8 x 9-1/4, 465 pp. Suggested Price: $229.95 / £146.00 Also available as an eBook

Advances in Chromatography

Grady Hanrahan California Lutheran University, Thousand Oaks, USA Series: Analytical Chemistry

Based on our knowledge of the functioning human brain, ANNs (artificial neural networks) serve as a modern paradigm for computing. Drawing on the author’s substantial experience, this book provides a comprehensive introduction and practical guide to the development, optimization, and application of ANNs in modern environmental and biological analysis. Presenting basic principles together with simulated biological and environmental data sets and real applications in the field, this volume helps scientists use the power of the ANN model to explain physical concepts and to demonstrate complex natural processes. Catalog no. K10638, ISBN: 978-1-4398-1258-7 January 2011, 6-1/8 x 9-1/4, 214 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

Edited by

Dynamic Force Spectroscopy and Biomolecular Recognition

Eli Grushka

Edited by

Hebrew University of Jerusalem, Israel

Anna Rita Bizzarri and Salvatore Cannistraro

Volume 51

Nelu Grinberg

Universita Della Tuscia, Viterbo, Italy

Boehringer-Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA

For more than four decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 51, the series editors have invited established, well-known chemists from across the globe to offer cutting-edge reviews on their areas of expertise. The clear presentation of topics and vivid illustrations for which this series has become known makes the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill.

38

Artificial Neural Networks in Biological and Environmental Analysis

Catalog no. K16450, ISBN: 978-1-4665-6965-2 April 2013, 6-1/8 x 9-1/4, 360 pp. Suggested Price: $229.95 / £146.00 Also available as an eBook

Molecular recognition, or biorecognition, is the heart of all biological interactions. Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. This book covers the most recent ideas and advances in the field of DFS applied to biorecognition. Leading experts in the field offer their perspectives on such important topics as atomic force microscopy, force spectroscopy, interaction geometries, and immobilization strategies. Catalog no. K12890, ISBN: 978-1-4398-6237-7 January 2012, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Electrokinetic Particle Transport in Micro-/Nanofluidics Textbook

Direct Numerical Simulation Analysis

Analytical Chemistry for Technicians

Shizhi Qian

Fourth Edition

Ye Ai

John Kenkel Southeast Community College, Lincoln, Nebraska, USA

Department of Mechanical and Aerospace Engineering, Old Dominion University, Norfolk, Virginia, USA Bioscience Division, Los Alamos National Laboratory, New Mexico, USA Series: Surfactant Science

This thoroughly updated fourth edition is designed to be a powerful training tool for entry-level chemistry technicians. This book explains analytical chemistry and instrumental analysis principles and how to apply them in the real world. Over 50 updated workplace scene sidebars with stories and photographs of technicians and chemists working with the equipment or performing the techniques discussed in the text brings the workplace of the chemical technician into the classroom. In addition, supplemental material is now available for download on the web. The text includes more than 60 experiments specifically relevant to the laboratory technician, along with questions and problems in each chapter.

This book provides a fundamental understanding of the electrokinetic particle transport in micro/nano-fluidics, involving electrophoresis, dielectrophoresis, electroosmosis, and induced-charge electroosmosis. It emphasizes the direct numerical simulation of electrokinetic particle transport phenomena, plus several supportive experimental studies. The authors use COMSOL Multiphysics® to conduct all the numerical simulations presented and include the corresponding script files in the book. The book is suitable as a resource for researchers in micro/nano-fluidics and as a supplementary textbook for course in electrokinetic transport phenomena in micro/nano-fluidics.

Figure slides are available upon qualifying course adoption

Catalog no. K12520, ISBN: 978-1-4398-5438-9 June 2012, 6 x 9, 398 pp. Suggested Price: $129.95 / £82.00

Catalog no. K13813, ISBN: 978-1-4398-8105-7 June 2013, 7 x 10, 625 pp. Suggested Price: $99.95 / £49.99

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Hyphenated and Alternative Methods of Detection in Chromatography

Encyclopedia of Chromatography Third Edition, Volume 1

R. Andrew Shalliker

Jack Cazes

University of Western Sydney, Australia

Consultant, Lady Lake, Florida, USA

Chromatographic Science Series

Thoroughly revised and expanded, this third edition offers illustrative tables and figures to clarify technical points in the articles and provides a valuable, readerfriendly reference for all those who employ chromatographic methods for analysis of complex mixtures of substances. An authoritative source of information, this introductory guide to specific chromatographic techniques and theory discusses the relevant science and technology, offering key references for analyzing specific chemicals and applications in industry and focusing on emerging technologies and uses.

Widely employed for separating and detecting chemicals in solution, separation techniques are most often applied in tandem, subsequently referred to as hyphenated methods. Hyphenated and Alternative Methods of Detection in Chromatography details the development and application of mass spectral detection techniques coupled with gas phase and liquid phase chromatographies. The book details the advantages and disadvantages of various separation techniques and addresses methods for cutting-edge applications such as proteomics research. This book provides a detailed reference for experienced readers as well as for those who are new to the field of separation and analysis.

Catalog no. 84593, ISBN: 978-1-4200-8459-7 October 2009, 8-1/2 x 11, 2850 pp. Suggested Price: $756.00 / £482.00 Also available as an eBook

Catalog no. 9077, ISBN: 978-0-8493-9077-7 December 2011, 6-1/8 x 9-1/4, 308 pp. Suggested Price: $169.95 / £103.00 Also available as an eBook

Handbook of Analytical Validation

Textbook

Cambridge, Massachusetts, USA

Introduction to Experimental Biophysics

Ira S. Krull

Biological Methods for Physical Scientists

Michael E. Swartz

Northeastern University, Boston, Massachusetts, USA

Written for practitioners in both the drug and biotechnology industries, this handbook carefully compiles the current regulatory requirements to correctly and properly validate a new or modified analytical method. The Handbook of Analytical Validation is designed to teach readers how to fully and correctly adapt new or modified analytical methods to meet regulatory requirements. The contents offer the latest regulatory requirements for submitting applications for new drugs or other applications, as regards analytical method validation. The chapters apply to both small molecules in the conventional pharmaceutical industry, as well the biotech industry. Catalog no. DK2235, ISBN: 978-0-8247-0689-0 April 2012, 6-1/8 x 9-1/4, 220 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Handbook of Near-Infrared Analysis

Jay Nadeau McGill University, Montreal, Quebec, Canada

A practical companion for physical scientists investigating wet laboratory experiments and biological research areas, this book gives a clear understanding of what is experimentally feasible. Introducing basic terminology and concepts, the text begins with simple, fundamental methods and builds gradually to more advanced techniques. Organized into three main sections addressing genes, proteins, and expression systems, this book employs a straight-forward structure allowing readers to follow the process involved in the production of nucleic acids and proteins and the different levels of purification required for each type of analysis. Figure slides are available upon qualifying course adoption

Catalog no. K11452, ISBN: 978-1-4398-2953-0 September 2011, 7 x 10, 672 pp., Soft Cover Suggested Price: $93.95 / £59.99 Also available as an eBook

Third Edition Edited by

Donald A. Burns NIR Resources, Los Alamos, New Mexico, USA

Emil W. Ciurczak Cadrai Technologies, Goldens Bridge, New York, USA Series: Practical Spectroscopy

Methods & Instrumentation

Edited by

Edited by

Introduction to GC-MS Spectrometry

Presenting nearly 50 percent new and revised material, this edition combines concise theoretical foundations with the latest advances in instrumentation, computerization, calibration, and methods in NIR spectroscopy. Drawing on the experience of more than 60 experts in the field, it underscores accurate, time and cost-effective current trends in sample preparation, calibration transfer, process control, data analysis, and commercial NIR instrumentation. New chapters highlight novel applications in pharmaceuticals, polymers, plastics, petrochemicals, textiles, foods and beverages, baked products, agricultural products, biomedicine, neutraceuticals, and counterfeit detection.

Without neglecting the fundamental theoretical aspects, this book emphasizes the practical aspects of gas chromatography—mass spectrometry, such as choosing the most successful device for a given application. It supports theoretical demonstrations with numerous examples, experience having shown the importance of illustrations in the understanding of the course. It lists the problems and the “traps” usually encountered by novice users, and tries to anticipate the mistakes which are most common in order to solve them.

Catalog no. 7393, ISBN: 978-0-8493-7393-0 September 2007, 7 x 10, 826 pp. Suggested Price: $249.95 / £159.00

Catalog no. K16604, ISBN: 978-1-4665-7251-5 February 2013, 6-1/8 x 9-1/4, 232 pp., Soft Cover Suggested Price: $79.95 / £49.99

Also available as an eBook

Also available as an eBook

Stéphane Bouchonnet

For more information and a complete list of titles, visit us at www.crcpress.com

39


Ion Mobility Spectrometry Third Edition G.A. Eiceman New Mexico State University, Las Cruces, USA Nuclear Research Center, Beer-Sheva, Israel

Expanding the Limits of Structure Elucidation

Herbert H. Hill, Jr.

Nina C. Gonnella

Z. Karpas

Methods & Instrumentation

Washington State University, Pullman, USA

Chromatographic Science Series

Beginning with a thorough discussion of the fundamental theories and physics of ion mobility, this third edition reference follows the traditional organization of the original, beginning with fundamental theories and physics of ion mobility. It then moves on to the recent advances in instrumentation and newly pioneered applications. Each chapter is thoroughly updated, with new information on present trends in IMS and coverage of FAIMS and DMS/MS. Significant expansion to the Biological and Biomedical section is provided, with an emphasis on LC ESI Mobility MS or ESI Mobility MS, including IMS TOF. The previously included CD-ROM is now available as a web page for qualified instructors.

The book is designed as a reference for chemists, NMR spectroscopists, chromatographers, students, and research professionals who are engaged in the isolation and NMR spectral characterization of complex organic molecules. The content guides the reader through the process of selecting the appropriate experiments and isolation systems while providing a foundation of basic theory and spectral interpretation. It discusses new and robust technologies that expand the limits of detection in NMR spectroscopy and includes examples of applications relevant to problems in pharmaceutical development.

Catalog no. K12739, ISBN: 978-1-4398-5997-1 December 2012, 6-1/8 x 9-1/4, 436 pp. Suggested Price: $149.95 / £95.00

Catalog no. K13480, ISBN: 978-1-4398-7506-3 February 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

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Laboratory Protocols in Applied Life Sciences Prakash Singh Bisen

40

LC-NMR

Linear and Chiral Dichroism in the Electron Microscope Edited by

Peter Schattschneider

Defense Research & Development Establishment, Gwalior, India

Vienna University of Technology, Austria

This manual includes details of methodologies used in diverse disciplines of life sciences including biotechnology, pharmaceutical sciences, medical sciences, and related fields. It provides the comprehensive information required to build a firm foundation in the life sciences. Due emphasis is given to techniques encountered both in practical classes but also in high throughput techniques involved in modern eras of commercialization and product inventories. Well illustrated to explain the theories behind each exercise, this book covers both basic techniques and also new, advanced techniques that continue to evolve and change.

This book describes energy loss magnetic chiral dichroism (EMCD), a phenomenon in energy loss spectroscopy discovered in 2006. EMCD is the equivalent of XMCD but is based on fast probe electrons in the electron microscope. A spatial resolution of 2 nm has been demonstrated, and the latticeresolved mapping of atomic spins appears feasible. EMCD is, thus, a promising technique for magnetic studies on the nanometer and sub-nanometer scale, providing the technical and logistic advantages of electron microscopy, such as in situ chemical and structural information, easy access, and low cost.

Catalog no. K15259, ISBN: 978-1-4665-5314-9 May 2013, 7 x 10, 500 pp., Soft Cover Suggested Price: $99.95 / £63.99

Catalog no. N10434, ISBN: 978-981-4267-48-9 March 2012, 6 x 9, 278 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Also available as an eBook

Laboratory Protocols in Applied Life Sciences Prakash Singh Bisen

Microbial Detection and Identification by Mass Spectrometry Edited by

Charles H. Wick

Defense Research & Development Establishment, Gwalior, India

Edgewood Chemical Biological Center, Aberdeen Proving Ground, Maryland, USA

This manual provides an easily accessible vehicle to a very wide range of laboratory protocols and procedures in the life sciences. This book is a comprehensive overview of laboratory techniques that are utilized by students and researchers in life sciences, pharmacy, biotechnology, microbiology, biochemistry, environmental sciences, food science, health sciences, and agricultural sciences. Due emphasis is placed on techniques encountered both in practical classes and in high throughput techniques involved in modern eras of commercialization and product inventories. The book is illustrated to explain the theories behind each exercise.

This book presents an in-depth examination of the process of detecting and identifying microbes using mass spectrometry techniques and the possibility of using this technology in a field application. Through a side-by-side comparative discussion of the different mass spectrometry approaches, it demonstrates the strengths and weaknesses of each approach. The book includes recent findings that show the detection of new viruses, new bacteria, fungi, and other microbes in complex environmental samples. It describes sample preparation methods and discusses the rational and methods for the detection and identification of unknown, genetically modified, or synthetic microbes.

Catalog no. K15466, ISBN: 978-1-4665-5736-9 February 2013, 7 x 10, 500 pp., Soft Cover Suggested Price: $99.95 / £63.99

Catalog no. K14546, ISBN: 978-1-4665-0494-3 June 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $139.95 / £89.00

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Also available as an eBook

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Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy

Quantitative Proteome Analysis

Emil W. Ciurczak

Edited by

Cadrai Technologies, Goldens Bridge, New York, USA

Kazuhiro Imai

Gary E. Ritchie

Musashino University, Tokyo, Japan

United States Pharmacopeia, Rockville, Maryland, USA

Sam Li Fong Yau

Series: Practical Spectroscopy

National University of Singapore

Exploring a versatile technology, this authoritative volume provides focused, single-source coverage of the instrumentation, computerization, calibration, and methods development of NIR spectroscopy. It examines novel applications for accurate time- and cost-effective analyses of pharmaceuticals as well as biomedical applications. The book contains chapters on the theory of diffuse reflection, the calibration and validation of process sensors, the new field of PAT (Process Analytical Technologies) in pharmaceutical applications, nutraceuticals, detection of counterfeit drugs, NIR spectrometry of abdominal aortic aneurysm, and new chemometric methods for biomedical components in blood and control serum.

This book focuses on the advantages and disadvantages of each of the commonly used quantitative proteomic methods in terms of accuracy, sensitivity, and reproducibility. It also concentrates on the effective applications of these methods that resulted in many discoveries of the role of the proteins expressed in living cells and biological fluids. The first part of the book focuses on the description of advantages and disadvantages of each of the commonly used quantitative proteomic methods in terms of accuracy, sensitivity, and, especially, reproducibility. The second part of the book focuses on providing concise descriptions of the effective applications of these methods to demonstrate how they have resulted in many important discoveries of the roles of the proteins expressed in living cells.

Catalog no. 84143, ISBN: 978-1-4200-8414-6 March 2013, 7 x 10, 350 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

Practical Guide and Spectral Atlas for Interpretive Near-Infrared Spectroscopy Second Edition

Catalog no. N10679, ISBN: 978-981-4316-51-4 January 2013, 6 x 9, 300 pp. Suggested Price: $199.95 / £127.00 Also available as an eBook

Vibrational Spectroscopy for Tissue Analysis Ihtesham ur Rehman Department of Materials Science and Engineering, The Kroto Research Institute, The University of Sheffield, UK

Jerry Workman, Jr. Unity Scientific LLC, Brookfield, Connecticut, USA

Zanyar Movasaghi

Lois Weyer

Dental Services, Barts Health NHS Trust, London, UK

Shazza Rehman

Landenberg, Pennsylvania, USA

Interpretive spectroscopy provides a basis for the establishment of cause-andeffect relationships between spectrometer response and the chemical properties of the samples. Without established cause-effect relationships, the measured data will have no true predictive significance. This interpretive process is key for achieving an analytical understanding of the measurement. The popular first edition of this text delivered a unique focus on structure correlation and interpretation of spectra for the practitioner. The thoroughly updated and revised second edition continues the tradition and includes a full library of color spectra in a larger format to ensure clarity and reader comprehension. Catalog no. K13491, ISBN: 978-1-4398-7525-4 April 2012, 8-1/2 x 11, 326 pp. Suggested Price: $199.95 / £127.00 Also available as an eBook

Airedale NHS Foundation Trust, Airedale General Hospital, UK Series in Medical Physics and Biomedical Engineering

This book presents a variety of vibrational spectroscopic techniques, focusing on Raman and Fourier transform infrared (FTIR) spectroscopy and their use in noninvasive optical tissue diagnosis. It covers the most recent research in this area to create a unique database of different chemical bands and their assignments of spectral bands. The text explores the spectroscopic investigation of different tissues and samples, including breast tissue, lung tissue, and brain tissue. Based on their years of experience with various applications, the authors provide definitions of peak frequencies as well as other aspects of spectroscopy that could be helpful to a wide range of scientists. Catalog no. K11629, ISBN: 978-1-4398-3608-8 October 2012, 6-1/8 x 9-1/4, 356 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

Practical Guide to ICP-MS A Tutorial for Beginners, Third Edition Robert Thomas Scientific Writing Solutions, Gaithersburg, Maryland, USA Series: Practical Spectroscopy

Presenting an in-depth discussion of the fundamental principles, analytical advantages, and practical capabilities of ICP-MS, this volume offers key concepts in a reader-friendly format suitable for those with limited knowledge of the technique. Written by an insider with more than 20 years experience in product development, customer support, and technical marketing for an ICPMS instrument vendor, the book highlights this powerful ultra trace-element technique as a practical solution to real-world problems. The new edition has been updated and revised to cover new developments and updates to existing applications and reflects the significant new technology introduced by vendors since the second edition published. Catalog no. K15371, ISBN: 978-1-4665-5543-3 May 2013, 6 x 9, 400 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Biological and Medical Sensor Technologies Edited by

Krzysztof Iniewski CMOS Emerging Technologies, Inc., Vancouver, British Columbia, Canada Series: Devices, Circuits, and Systems

Edited by a pioneer in the area of advanced semiconductor materials, this book contains contributions from experts who explore the development and use of sensors in biological and medical applications. It covers advanced sensing and communications, modeling of DNA-derivative architecture, and the use of enzyme and quartz crystal microbalance-based biosensors. The book also addresses biosensors in human behavior measurement, sweat rate wearable sensors, and the future of medical imaging, including developments in spatial and spectral resolution of semiconductor detectors. Contributors discuss application of high-resolution CdTe detectors in gamma ray imaging and recent advances in positron emission tomography technology. Catalog no. K13895, ISBN: 978-1-4398-8267-2 February 2012, 6-1/8 x 9-1/4, 412 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

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Methods & Instrumentation / Nanobiotechnology

Methods and Applications

41


Biomaterials for Stem Cell Therapy State of Art and Vision for the Future Edited by

Loredana De Bartolo Institute on Membrane Technology, Rende, Italy

Augustinus Bader Center for Biotechnology and Biomedicine (BBZ), Leipzig, Germany

Deliberative Processes, Social Barriers and Methodologies Harald Throne-Holst, Eivind Soto, Pal Strandbakken, and Gerd Scholl

Nanobiotechnology

This book provides the state-of-the-art developments with a specific focus on the interaction of stem cells with biomaterials for constructing and regenerating tissues and organs integrating strategies from basic biology, to materials for remodeling to production processes. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to, nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair, and cardiovascular therapy. All developments in the field reflecting the design and construction of the human body and its principal anatomy will be discussed from a materials point of view.

In recent years, questions about democratic influence on science and technology have received much attention. The lesson from the European unrest over GMO is that consumer-citizens will react negatively to just having to accept the introduction of new, partly untested technologies. A number of political bodies have started to involve citizens and to consider their concerns, attitudes, hopes, and worries in an early stage of the coming nano revolution. An international consortium of experts mapped a large number of these deliberations, mainly in the European Union and the United States, and proceeded to give closer analysis of a selection of those that were found most interesting. The second part of the book analyzes seven citizen-oriented deliberations. The third part of the book looks into a set of more stakeholder-oriented deliberations.

Catalog no. K16738, ISBN: 978-1-4665-7639-1 January 2013, 6-1/8 x 9-1/4, 570 pp. Suggested Price: $189.95 / £121.00

Catalog no. N10492, ISBN: 978-981-4316-16-3 November 2012, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

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Cadmium Telluride Quantum Dots

DNA Liquid-Crystalline Dispersions and Nanoconstructions

Advances and Applications Edited by

John Donegan and Yury Rakovich

42

Consumers and Nanotechnology

Yuri M. Yevdokimov, V.I. Salyanov, S.V. Semenov, and S.G. Skuridin Engelhardt Institute of Molecular Biology, Moscow, Russian Federation

Trinity College Dublin, Ireland

Liquid Crystals Book Series

Among nanomaterials, CdTe holds special technological importance as the only known II–VI material that can form conventional p–n junctions. This makes CdTe very important for the development of novel optoelectronic devices such as lightemitting diodes, solar cells, and lasers. This book focuses on CdTe quantum dots and addresses their synthesis, assembly, optical properties, and applications in biology and medicine. It makes for a very informative reading for anyone involved in nanotechnology and will also benefit those scientists who are looking for a comprehensive account on the current state of quantum dot-related research.

With detailed coverage of DNA liquid crystals, this book explores the information available on the condensation of various forms of DNA. The text presents the practical applications of the peculiar properties of the liquid-crystalline state of nucleic acids. It also shows how double-stranded nucleic acids represent an important tool for nanotechnology. The authors address modeling the state of the DNA molecules under laboratory conditions, which clarifies of the role of these molecules in living cells and for directed, artificial regulation of biological activity of the DNA by various chemical and biologically active compounds of medical importance.

Catalog no. N10697, ISBN: 978-981-4316-05-7 February 2013, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00

Catalog no. K13273, ISBN: 978-1-4398-7146-1 September 2011, 6-1/8 x 9-1/4, 304 pp. Suggested Price: $146.95 / £94.00

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Cancer Nanotechnology Principles and Applications in Radiation Oncology Edited by

Sang Hyun Cho

DNA Nanotechnology

Georgia Institute of Technology, Atlanta, USA

Satyam Priyadarshy

Sunil Krishnan

RKR Group, Inc., Herndon, Virginia, USA

University of Texas, MD Anderson Cancer Center, Houston, USA

Latha Shankar

Reflecting profound advances in the application of nanotechnology to radiation oncology, this comprehensive volume demonstrates how the unique physicochemical properties of nanoparticles lead to novel strategies for cancer treatment and detection. Along with various computational and experimental techniques, each chapter highlights the most promising approaches, including the use of nanoparticles for radiation response modulation and thermal ablation treatment of tumors. Other topics covered include radiation dose enhancement, imaging the biodistribution of nanoparticles, carbon nanotubes for thermal therapy, radioprotection by nanomaterials, and nanoparticle-mediated radiosensitization.

DNA is a versatile molecule, ideal for building complex structures at the nanometer scale, yet until now scientists have lacked for a cohesive reference that details nanotechnology applications in which DNA plays a key role. A tremendous aid to researchers, this work describes current applications across many fields including robotics, lithography, computation, electronics, and fabrication. Whether you are building biomedical scaffolds, designing molecular motors, or producing nanowires, sensors, solar cells or new fuels, this work will inform you as to what has been accomplished, while expanding your understanding of what is possible.

Catalog no. K13683, ISBN: 978-1-4398-7875-0 January 2013, 8-1/2 x 11, 288 pp. Suggested Price: $169.95 / £108.00

Catalog no. 86332, ISBN: 978-1-4200-8633-1 April 2013, 6-1/8 x 9-1/4, 464 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Also available as an eBook

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Microfluidics and Nanofluidics Handbook Introduction to Nanoscience and Nanotechnology Gabor L. Hornyak, H.F. Tibbals, Joydeep Dutta, and John J. Moore The maturation of nanotechnology has revealed it to be a unique and distinct discipline rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry, physics, or engineering text focused on nano. It must be an integrated and multidisciplinary nano textbook. The archetype of the modern nano textbook, this text builds a solid background in characterization and fabrication methods while integrating the physics, chemistry, and biology facets. The remainder of this color text focuses on applications, examining engineering aspects as well as nanomaterials and industry-specific applications in such areas as energy, electronics, and biotechnology. A solutions manual is available upon qualifying course adoption

Buy the set and save! Catalog no. 47795, ISBN: 978-1-4200-4779-0 December 2008, 7 x 10, 1640 pp. Suggested Price: $157.95 / £101.00 Also available as an eBook

Individual volumes also available

Chemistry, Physics, and Life Science Principles Edited by

Sushanta K. Mitra University of Alberta, Edmonton, Canada

Suman Chakraborty Indian Institute of Technology (IIT), Kharagpur

A comprehensive, two-volume handbook on microfluidics and nanofluidics, this text covers fundamental aspects, fabrication techniques, introductory materials on microbiology and chemistry, measurement techniques, and applications with special emphasis on the energy sector. Each chapter begins with introductory coverage of a subject and then narrows in on advanced techniques and concepts, thus making it valuable to students and practitioners. The author pays special attention to applications of microfluidics in the energy sector and provides insight into the world of opportunities nanotechnology has to offer. Figures, tables, and equations are used to illustrate concepts. Catalog no. K10862, ISBN: 978-1-4398-1676-9 September 2011, 7 x 10, 1125 pp. Suggested Price: $189.95 / £121.00 Also available as an eBook

Modeling and Control for Micro/ Nano Devices and Systems

Textbook

Edited by

Fundamentals of Nanotechnology

Ning Xi Michigan State University, East Lansing, USA

Winner 2009 CHOICE Award Outstanding Academic Title!

Mingjun Zhang

Catalog no. 48031, ISBN: 978-1-4200-4803-2 December 2008, 7 x 10, 786 pp. Suggested Price: $99.95 / £62.99 Also available as an eBook

Textbook

Introduction to Nanoscience Catalog no. 48058, ISBN: 978-1-4200-4805-6 May 2008, 7 x 10, 856 pp. Suggested Price: $99.95 / £62.99 Also available as an eBook

University of Tennessee, Knoxville, USA

Guangyong Li University of Pittsburgh, Pennsylvania, USA Series: Automation and Control Engineering

As the first edited volume on the topic, this book focuses on providing a unified overview of the rapidly emerging field of micro/nano system modeling and control. It gives managers, researchers, and graduate students easy access to the expert contributors’ cutting-edge knowledge and skills in this crucial field. To this point, very little has been published on this subject, so the editors present an especially wide-ranging overview, covering topics as diverse as micro/nano devices, systems biology, and sensors. Catalog no. K15303, ISBN: 978-1-4665-5405-4 February 2013, 6 x 9, 200 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Nanoantenna

Life at the Nanoscale Atomic Force Microscopy of Live Cells

Plasmon-Enhanced Spectroscopies for Biotechnological Applications

Edited by

Edited by

Yves Dufrene

Marc Lamy de la Chapelle

Universite Catholique de Louvain, Louvain-la-Neuve, Belgium

Nanobiotechnology

Textbook

Université Paris 13, Bobigny, France

Annemarie Pucci

This timely book provides a comprehensive overview of the use of AFM and related scanning probe microscopies for cell surface analysis, going from the basics to the applications side. It covers all cell types, going from viruses and protoplasts to bacteria and animal cells and to discuss a range of advanced AFM modalities, including high-resolution imaging, nanoindentation measurements, recognition imaging, and single-molecule and single-cell force spectroscopy. The book covers methodologies for preparing and analyzing cells and membranes of all kinds and highlights recent examples to illustrate the power of AFM techniques in life sciences and nanomedicine.

This book concentrates on the various fields related to the development of a nanobiosensor and presents the latest information from renowned experts. It focuses on the enhanced spectroscopy, including SERS, SEIRA/SEIRS, and nearfield optics, and the related physical processes (optical properties of metallic nanoparticles, plasmon resonance, field enhancement, etc.). Some applications in the biological and medical field are presented to show the potential of such techniques as sensors if combined with functionalization.

Catalog no. N10435, ISBN: 978-981-4267-96-0 August 2011, 7 x 10, 460 pp. Suggested Price: $149.95 / £95.00

Catalog no. N10570, ISBN: 978-981-4303-61-3 August 2012, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

Also available as an eBook

Kirchhoff-Institut für Physik, Heidelberg, Germany

For more information and a complete list of titles, visit us at www.crcpress.com

43


Nanomedicine and Drug Delivery Edited by

Nanobrain Making an Intelligent Molecular Machine Anirban Bandyopadhyay

Mahatma Gandhi University, Kerala, India

A. K. Haghi University of Guilan, Iran

Nanobiotechnology

National Institute for Materials Science, Ibaraki, Japan

Series: Advances in Nanoscience and Nanotechnology

Written for computer scientists, materials scientists, and others in fields related to nanotechnology, this reference explores recent efforts to realize a practical physical device that follows the neural network principles of the brain, incorporating research from the last 50 years in nanotechnology, artificial intelligence, supramolecular chemistry, and materials science. The author adopts a multidisciplinary approach, addressing fundamental problems in computer science, organic synthesis, theoretical physics, supramolecular chemistry, and artificial intelligence in a lucid, accessible way and references major breakthrough papers that have changed the course of scientific development. A color insert is included, as well as a CD with additional material.

This forward-looking book focuses on the recent advances in nanomedicine and drug delivery. It outlines the extraordinary new tools that have become available in nanomedicine and presents an integrated set of perspectives that describe where we are now and where we should be headed to put nanomedicine devices into applications as quickly as possible, while also considering the possible dangers of nanomedicine.

Catalog no. K13502, ISBN: 978-1-4398-7549-0 February 2013, 6-1/8 x 9-1/4, 304 pp., Soft Cover Suggested Price: $149.95 / £95.00 Also available as an eBook

Catalog no. N10640, ISBN: 978-1-926895-17-8 July 2012, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Nanostructures and Nanoconstructions Based on DNA Yuri M. Yevdokimov, V.I. Salyanov, and S.G. Skuridin

Textbook

Nanoelectronics Devices, Circuits, and Systems Nikos Konofaos Associate Professor, Aristotle University of Thessaloniki, Greece Series: Devices, Circuits, and Systems

44

Mathew Sebastian Neethu Ninan

The book provides information on all aspects of modern nanoelectronics. It does not require advanced mathematics or hard knowledge of chemistry, and approaches the issue from the engineering point of view, with physics used when needed. Every chapter includes questions for understanding and topics for discussion. Problems will also be supplied at the end of the book on selective issues where the students need to practice some calculations and use their skills in order to compare different devices and systems. Catalog no. K13463, ISBN: 978-1-4398-7468-4 April 2013, 6-1/8 x 9-1/4, 350 pp. Suggested Price: $99.95 / £63.99

Engelhardt Institute of Molecular Biology, Moscow, Russian Federation Liquid Crystals Book Series

Written for chemists, physicists, molecular biologists, and students in related fields, this reference covers information presently available on the specific properties of metallic nanoparticles, and compares their properties with those related to nanoobjects formed by biological molecules. It also discloses details of formation and physicochemical peculiarities of the DNA nanostructures and DNA-based nanoconstructions. Timely in publication, the reference contains more DNA physics and molecular biology than other published titles. Authors discuss how nucleic acid molecules and their complexes with chemical and biologically active compounds are of great interest in the development of various nanoscale systems and devices of practical importance. Catalog no. K14579, ISBN: 978-1-4665-0569-8 June 2012, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Also available as an eBook

Nanotechnology Nanomedicine and Cancer Therapies Edited by

Mathew Sebastian Neethu Ninan Mahatma Gandhi University, Kerala, India

Eldho Elias

The Whole Story Ben Rogers Reno, Nevada, USA

Jesse Adams Nevada Nano, Inc., Reno, USA

Sumita Pennathur University of California, Santa Barbara, USA

This book presents a wealth of information and research about the most potent cancer healing therapies, focusing particularly how nanomedicine, holistic medicine, and other cancer therapies play important roles in treating cancer. Nanotechnology has the power to radically change the way cancer is diagnosed, imaged, and treated. The holistic approach to cancer involves noninvasive procedures focused upon restoring the health of human energy fields.

This book communicates, in easy-to-understand language, tough-to-understand concepts, providing a comprehensive reference for technically interested/trained laymen in the general public interested in learning more about this revolutionary, high impact field of technology. The amount and level of math used in the pedagogy of the text has been reduced to cater to the general audience, and the book includes behind-the-scenes stories of Nobel-prize-winning scientists of eureka moments or the back-of-the-envelope calculations showing real-world numbers of nanotechnology. Thematic figures have been added to pique the interest and guide readers.

Catalog no. N10641, ISBN: 978-1-926895-18-5 July 2012, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $149.95 / £95.00

Catalog no. K14290, ISBN: 978-1-4398-9780-5 March 2013, 6-1/8 x 9-1/4, 402 pp. Suggested Price: $69.95 / £44.99

Also available as an eBook

Also available as an eBook

Mahatma Gandhi University, India Series: Advances in Nanoscience and Nanotechnology

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Responsible Nanobiotechnology

Neuroviral Infections Edited by

Sunit K. Singh

Armin Grunwald Karlsruhe Institute of Technology, Germany

This book comprehensively reviews the considerations of nanotechnology elaborated in philosophy, ethics, and the social sciences and systematizes and develops them further. It focuses on the issues of ethical responsibility regarding chances and risks of nanotechnology and its possible applications in the fields of synthetic nanoparticles, synthetic biology, animal enhancement, and human enhancement. The book has been, thus, put in the context of the keywords “responsible innovation” and “reflective sciences,” which have been central concepts in the debates about the relationship between science and society for the last few years. Catalog no. N10506, ISBN: 978-981-4316-80-4 October 2012, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Centre for Cellular and Molecular Biology, Hyderabad, India

Daniel Ruzek Biology Centre ASCR- Institute of Parasitology, Ceske Budejovice, Czech Republic

Viral infections of the central nervous system or neurotropic viruses are often lethal. Understanding of these diseases involves understanding the interaction between the nervous system and the immune system. This book provides indepth information about each individual virus, the diseases they cause, and the mechanisms of the spread of those diseases. Addressing both clinical and basic science aspects, the text covers such diseases as polio, measles, rabies, herpes, West Nile, Japanese encephalitis, and varicella-zoster. The authors also include detailed discussions of molecular pathogenesis and host pathogen immune interaction as well as disease detection, treatment, and prevention.

Buy the set and save!

Self-Assembled Peptide Nanostructures Advances and Applications in Nanobiotechnology

Catalog no. K13120, ISBN: 978-1-4398-6852-2 February 2013, 6-1/8 x 9-1/4, 914 pp. Suggested Price: $279.95 / £178.00 Also available as an eBook

Individual volumes also available

Neuroviral Infections

Edited by

Jaime Castillo, Luigi Sasso, and Winnie Edith Svendsen

General Principles and DNA Viruses

Technical University of Denmark, Lyngby

This book introduces readers to the theory and mechanisms of peptide selfassembly processes. The authors present the more common peptide selfassembled building blocks and discuss how researchers from different fields can apply self-assembling principles to bionanotechnology applications. The advantages and challenges are mentioned together with examples that reflect the state of the art of the use of self-assembled peptide building blocks in nanotechnology.

Catalog no. K16317, ISBN: 978-1-4665-6719-1 February 2013, 6-1/8 x 9-1/4, 392 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

Neuroviral Infections RNA Viruses and Retroviruses

Catalog no. N10551, ISBN: 978-981-4316-94-1 November 2012, 6 x 9, 250 pp. Suggested Price: $149.95 / £95.00

Catalog no. K16318, ISBN: 978-1-4665-6720-7 February 2013, 6-1/8 x 9-1/4, 522 pp. Suggested Price: $159.95 / £99.00

Also available as an eBook

Also available as an eBook

Simulations in Nanobiotechnology

Applications of Proteomics to Cell Signaling

Edited by

Edited by

Kilho Eom

Iyer Srinivas

Korea University, Seoul, South Korea

Nanobiotechnology / Immunology / Cell Biology

Two-Volume Set

Philosophy and Ethics

Los Alamos National Laboratory, New Mexico, USA Series: Methods in Signal Transduction

Until recently, computational studies of biomolecules and nanomaterials have considered the two subjects separately. This book provides insights into computational simulations of biomolecules and nanomaterials collectively. It also examines novel modeling concepts at the nano-bio-interface: interactions between biomolecules and nanomaterials, such as DNA-wrapped nanotubes, nanobiosensors, and biomimetic materials. Expert contributors from around the world address such important topics as the molecular dynamics of protein translocation, coarse-grained modeling of CNT-DNA interaction, multi-scale modeling of nanowire resonator sensors, and the molecular dynamics simulation of protein mechanics.

The field of proteomics has had a tremendous impact on our understanding of biological systems. While proteomics encompasses multiple approaches, the application of mass spectrometry-based techniques has generated large, information-rich data sets that have enabled a much clearer understanding of areas such as cell signaling. For example, protein post-translational modifications such as phosphorylation are critically involved in signal transduction in almost all biological systems; much progress has been made to identify these protein alterations during signal transduction. This book focuses specifically on the application of these approaches to understanding signaling in biological systems.

Catalog no. K11581, ISBN: 978-1-4398-3504-3 October 2011, 6-1/8 x 9-1/4, 562 pp. Suggested Price: $139.95 / £89.00

Catalog no. K11856, ISBN: 978-1-4398-4010-8 June 2013, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

45


Handbook of Dynein Biomimicry

Keiko Hirose

Architecture and Design

National Institute of Advanced Industrial Science & Technology, Ibaraki, Japan

Ilaria Mazzoleni

Linda A. Amos

Cell Biology

Southern California Institute of Architecture, Los Angeles, USA

MRC Laboratory of Molecular Biology, Cambridge, UK

Biology influences design projects in many ways; the related impact is known as biomimetics or biomimicry. Investigating the animal kingdom as a source of inspiration, this book focuses on the analysis of various animal skins, translating the learned principles into the built environment. Skin is a complex organ that performs various functions; similarly, building envelopes serve multiple roles as interfaces between building inhabitants and environmental elements. The resulting architectural building coverings take into consideration dynamic local environmental conditions. The text illustrates how supporting biomimetic principles can create a more sustainable way of building and living.

This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give readers a clear picture of what is currently known about the structure and mechanics of these remarkable macromolecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. This is a useful handbook for frontline researchers as well as a textbook for advanced students.

Catalog no. K14605, ISBN: 978-1-4665-0607-7 February 2013, 7 x 9, 256 pp. Suggested Price: $99.95 / £63.99

Catalog no. N10470, ISBN: 978-981-4303-33-0 February 2012, 6 x 9, 350 pp. Suggested Price: $199.95 / £127.00 Also available as an eBook

Handbook of Therapeutic Biomarkers in Cancer

Textbook

Biophysics for Beginners

Edited by

A Journey through the Cell Nucleus

National Cancer Institute, Bethesda, Maryland, USA

Helmut Schiessel

46

Edited by

Sherry X. Yang Janet E. Dancey

Leiden University, The Netherlands

Ontario Institute for Cancer Research, Toronto, Canada

This textbook gives compact introductions to the basics of the field (areas such as molecular cell biology and statistical physics) and then presents in-depth discussions of more advanced biophysics subjects, progressing to state-of-theart experiments and their theoretical interpretations. The book is unique by offering a general introduction to biophysics, yet at the same time restricting itself to processes that occur inside the cell nucleus and that involve biopolymers (DNA, RNA, and proteins). This allows for an accessible read for beginners and a springboard for specialists who wish to continue their study in more detail.

In this volume, a team of internationally recognized experts provide an in-depth description of therapeutic biomarkers across a broad area of cancer research and oncology. With a wealth of information to specific therapies, each chapter focuses on a class of targeted chemotherapy agents. The book describes established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions. This volume is an essential handbook for health professionals and scientists researching current applicable biomarkers in oncology.

Catalog no. N10567, ISBN: 978-981-4241-65-6 February 2013, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00

Catalog no. N10578, ISBN: 978-981-4364-65-2 December 2012, 6 x 9, 450 pp. Suggested Price: $179.95 / £114.00

Also available as an eBook

Also available as an eBook

Inflammation, Lifestyle, and Chronic Diseases

Cytokines

The Silent Link

Edited by

Edited by

Victor R. Preedy

Bharat B. Aggarwal, Sunil Krishnan, and Sushovan Guha

King’s College Hospital, London, UK

Ross Hunter

University of Texas, MD Anderson Cancer Center, Houston, USA

St. Bartholomew’s Hospital, London, UK

Series: Oxidative Stress and Disease

Cytokines are a group of peptides secreted by cells of the immune system such as macrophages, lymphocytes, and T cells. They can be divided into functional families and have wide-ranging impacts that affect cells and molecular pathways to the whole individual. Written by distinguished scholars and experts, this book is a holistic reference to enable scientists and doctors to understand cytokines in specific or broad detail. The book is divided into sections that cover general and cellular aspects, lifestyle factors, immunology and infections, cancer, cardiovascular and metabolic disease, and organs and tissue systems.

Discussing the role of dysregulated inflammation and lifestyle in chronic diseases, this book looks at the link between inflammation and a range of disorders such as neurodegenerative, pulmonary, rheumatic, arthritic, gastrointestinal, skin, heart, and infectious diseases; asthma; insulin resistance; cancer; neuropsychiatric disorders; and chronic wounds. For each ailment, contributors review the clinical and scientific literature, examine current and potential therapies, and suggest directions for future research. Exploring how the suppression of proinflammatory pathways may provide opportunities for prevention and treatment, the book examines conventional pharmacotherapies such as steroids and NSAIDs alongside anti-inflammatory dietary agents.

Catalog no. N10368, ISBN: 978-1-57808-690-0 June 2011, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $179.95 / £114.00 Also available as an eBook

Catalog no. K11838, ISBN: 978-1-4398-3989-8 July 2011, 6-1/8 x 9-1/4, 504 pp. Suggested Price: $157.95 / £101.00 Also available as an eBook

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Edited by

Sten Orrenius

The Structure of Biological Membranes

Karolinska Institute, Stockholm, Sweden

Third Edition

Lester Packer and Enrique Cadenas

Edited by

University of Southern California, Los Angeles, USA

Philip L. Yeagle

Series: Oxidative Stress and Disease

Rutgers University, Newark, New Jersey, USA

Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. This volume examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis. Topics include electron transport and energy production, mitochondrial biogenesis and dynamics, mitochondrial signaling, and apoptosis and autophagy. The book also explores pharmacology signaling and epigenetic signaling, with discussions on mitochondrial methylation and acetylation reactions. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.

Completely revised and updated to reflect advances in the study of biological membranes, this third edition provides an integrated view of membrane structure and function. Introductory chapters focus on the fundamentals of lipid bilayers and membrane proteins for those new to the field. The second part of the book presents in-depth analyses of current topics, including the phase behavior of lipid bilayers; cholesterol’s role in cell biology; the lateral organization of membranes; the role of lipids in membrane protein folding; membrane protein synthesis, stability, and transport; and interactions between proteins and lipids. It offers a valuable resource for researchers and students alike.

Catalog no. K13756, ISBN: 978-1-4398-8002-9 June 2012, 6-1/8 x 9-1/4, 528 pp. Suggested Price: $149.95 / £95.00

Catalog no. K10479, ISBN: 978-1-4398-0957-0 July 2011, 7 x 10, 398 pp. Suggested Price: $167.95 / £107.00 Also available as an eBook

Also available as an eBook

Regenerative Medicine, Stem Cells and the Liver David C. Hay MRC Centre for Regenerative Medicine, University of Edinburgh, UK

Atlas of Fish Histology Franck Genten, Eddy Terwinghe, and André Danguy

The regenerative capacity of the liver has been recognized for centuries, but when it is overwhelmed by insulting stimuli or is chronically damaged, its regenerative capability is substantially reduced or lost. Researchers have been working to find solutions to cure failing human liver function. Given the ability of stem cells to self-renew and differentiate into specialized cell liver types, they represent an attractive strategy to replace lost liver function. This book begins by outlining the complex nature of human liver disease and proceeds to examine the potential that stem cell-based approaches have to offer. Catalog no. N10558, ISBN: 978-1-57808-739-6 April 2012, 6-1/8 x 9-1/4, 200 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging

Many books emphasize the pathological histology of fish, but this volume fills a gap in the literature by focusing on normal fish histology. A general reference guide, it provides an extensive set of histological images of fish, discussing approximately 40 species. The book presents histology as a discipline—including its methodology and techniques—and its goals of investigating the structure and function of tissue samples. By histologically examining the normal physiology of fish tissue, scientists can gain insight into signs of disease not easily recognized on gross examination. Catalog no. N00092, ISBN: 978-1-57808-544-6 January 2009, 6 x 9, 223 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Biodefense Research Methodology and Animal Models

Edited by

Second Edition

Dara L. Kraitchman

Edited by

Johns Hopkins University, Baltimore, Maryland, USA

James R. Swearengen

Joseph C. Wu Stanford University School of Medicine, California, USA Series in Medical Physics and Biomedical Engineering

A comprehensive overview of cell therapy imaging, this book emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. It presents background information and insight on the major classes of stem and progenitor cells and describes the main imaging modalities and state-of-the-art techniques currently employed for stem cell tracking. The book also offers clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Catalog no. K10383, ISBN: 978-1-4398-0751-4 November 2011, 6-1/8 x 9-1/4, 489 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Cell Biology / Lab Animal Science

Mitochondrial Signaling in Health and Disease

National Biodefense Analysis and Countermeasures Center, Frederick, Maryland, USA

Since the publication of the first edition of this volume, significant advances have been made in animal model development for biological research and the ramifications of the FDA’s Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, this volume spans the spectrum of coverage from basic research to advanced development of medical countermeasures. Topics discussed include a history of biological agents as weapons, concepts, and strategies involved in biowarfare and bioterrorism, animal models in biodefense research, and infectious disease aerobiology. The book also presents studies involving a range of specific diseases and toxins. Catalog no. K11643, ISBN: 978-1-4398-3632-3 February 2012, 6-1/8 x 9-1/4, 415 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

47


Laboratory Animal Pocket Reference Series Thirteen-Volume Set Edited by

Mark A. Suckow University of Notre Dame, Indiana, USA Series: Laboratory Animal Pocket Reference

The Laboratory Animal Pocket Reference Series discusses procedures that ensure laboratory animals receive the best, most humane, and most responsible care possible. The 13 volumes are compact and comb-bound to lay flat for use in the laboratory. The contents of each includes important biological features, husbandry, management, veterinary care, regulatory concerns, and commonly used and new procedures, as well as an invaluable list of suppliers. Each book in the series can be purchased individually or as part of the set.

Lab Animal Science

Save on the Set! Catalog no. 2560, ISBN: 978-0-8493-2560-1 March 2000, 7-1/2 x 9-1/4, 167 pp. Suggested Price: $649.95 / £414.00

The Laboratory Canine Garrett Field Eli Lilly and Company, Indianapolis, Indiana, USA

Todd A. Jackson

The Laboratory Mouse Second Edition Peggy J. Danneman The Jackson Laboratory, Bar Harbor, Maine, USA

Mark A. Suckow University of Notre Dame, Indiana, USA

Cory Brayton Johns Hopkins University, Baltimore, Maryland, USA

Catalog no. K12511, ISBN: 978-1-4398-5421-1 October 2012, 6-1/8 x 9-1/4, 256 pp., Soft Cover Suggested Price: $59.95 / £38.99

The Laboratory Nonhuman Primate Mark A. Suckow University of Notre Dame, Indiana, USA

Catalog no. 2562, ISBN: 978-0-8493-2562-5 September 2001, 6-1/8 x 9-1/4, 288 pp., Soft Cover Suggested Price: $59.95 / £38.99

The Laboratory Rabbit

Bristol-Myers Squibb, Evansville, Indiana, USA

Second Edition

Catalog no. 2893, ISBN: 978-0-8493-2893-0 October 2006, 6-1/8 x 9-1/4, 184 pp., Soft Cover Suggested Price: $59.95 / £38.99

Mark A. Suckow and Valerie Schroeder University of Notre Dame, Indiana, USA

Fred A. Douglas Purdue University, West Lafayette, Indiana, USA

The Laboratory Cat Brent J. Martin Medical College of Ohio, Toledo, USA

Catalog no. 2567, ISBN: 978-0-8493-2567-0 November 1997, 6-1/8 x 9-1/4, 160 pp., Soft Cover Suggested Price: $59.95 / £38.99

The Laboratory Ferret

48

C. Andrew Matchett, Rena Marr, Felipe M. Berard, Andrew G. Cawthon, and Sonya P. Swing Catalog no. K12861, ISBN: 978-1-4398-6181-3 March 2012, 6-1/8 x 9-1/4, 123 pp., Soft Cover Suggested Price: $59.95 / £38.99 Also available as an eBook

The Laboratory Guinea Pig Second Edition Donna J. Clemons and Jennifer L. Seeman Covance Laboratories Inc., Madison, Wisconsin, USA

Catalog no. K11598, ISBN: 978-1-4398-3556-2 June 2011, 6-1/8 x 9-1/4, 172 pp., Soft Cover Suggested Price: $59.95 / £38.99

The Laboratory Hamster & Gerbil Karl J. Field Bristol Myers Veterinary Sciences, Flemington, New Jersey, USA

Amber L. Sibold

Catalog no. 91050, ISBN: 978-1-4200-9105-2 April 2010, 6-1/8 x 9-1/4, 148 pp., Soft Cover Suggested Price: $59.95 / £38.99

The Laboratory Rat Second Edition Patrick E. Sharp National University of Singapore

Jason Villano The Pennsylvania State University Hershey Medical Center, USA

Catalog no. K11462, ISBN: 978-1-4398-2986-8 December 2012, 6-1/8 x 9-1/4, 406 pp., Soft Cover Suggested Price: $59.95 / £38.99 Also available as an eBook

The Laboratory Small Ruminant Matthew J. Allen SUNY Health Science Center, Syracuse, New York, USA

Gary L. Borkowski Consultant, Saint Louis, Missouri, USA Series: Laboratory Animal Pocket Reference

Catalog no. 2568, ISBN: 978-0-8493-2568-7 March 1999, 6-1/8 x 9-1/4, 176 pp., Soft Cover Suggested Price: $59.95 / £38.99

The Laboratory Swine Second Edition Peter J. A. Bollen

Consultant, East Hanover, New Jersey, USA

University of Southern Denmark, Odense

Catalog no. 2566, ISBN: 978-0-8493-2566-3 December 1998, 6-1/8 x 9-1/4, 168 pp., Soft Cover Suggested Price: $59.95 / £38.99

University of Copenhagen, Frederiksberg, Denmark

Axel K. Hansen Aage K Olsen Alstrup Aarhus University Hospital, Aarhus, Denmark

Catalog no. K10783, ISBN: 978-1-4398-1528-1 February 2010, 6-1/8 x 9-1/4, 138 pp., Soft Cover Suggested Price: $59.95 / £38.99 www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-561-994-0555 • +44 (0) 1235 400 524


The Laboratory Xenopus sp. Sherril L. Green Stanford University, California, USA

Catalog no. 91093, ISBN: 978-1-4200-9109-0 December 2009, 6-1/8 x 9-1/4, 180 pp., Soft Cover Suggested Price: $59.95 / £38.99

Handbook of Laboratory Animal Science Third Edition, Volume I, Essential Principles and Practices Edited by

Jann Hau University of Copenhagen & Rigshospitalet, Denmark

Steven J. Schapiro

Edited by

Claudia Harper Amgen Inc., Cambridge, Massachusetts, USA

Christian Lawrence Children’s Hospital Boston, Massachusetts, USA

Catalog no. K10378, ISBN: 978-1-4398-0743-9 December 2010, 6-1/8 x 9-1/4, 274 pp., Soft Cover Suggested Price: $59.95 / £38.99

The University of Texas MD Anderson Cancer Center, Bastrop, USA

Now in its third edition, this comprehensive handbook explores the myriad issues surrounding the use of animals in scientific laboratories. Topics in Volume I include the history of animal research, ethical concerns, regulation and legislation, facilities and equipment, genetics, health monitoring, nutrient requirements and feeding schedules, statistical analysis, surgical and non-surgical techniques, and anesthesia. The book also explores alternatives to lab animal use with a discussion of the refinement, reduction, and replacement of animal uses in the life sciences. The book boasts an array of international contributors. Catalog no. 84550, ISBN: 978-1-4200-8455-9 December 2010, 7 x 10, 740 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Handbook of Laboratory Animal Science

Current Research in Animal Physiology

Third Edition, Volume II, Animal Models

Edited by

Victor S. Lamoureux Broome Community College, Binghamton, New York, USA

Animal physiology is the scientific study of how the bodies of animals function. How does an animal breathe, develop, eat and digest, reproduce, and control its activities? The field encompasses the molecular, cellular, tissue, and organ systems of animals. This book looks at an eclectic selection of studies in animal physiology, including how animals adapt to their physical environments, how human interaction can affect animal functioning, and much more. Catalog no. N10605, ISBN: 978-1-926692-79-1 December 2011, 6-1/8 x 9-1/4, 318 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Edited by

Jann Hau and Steven J. Schapiro This third edition of a bestselling handbook explains the comparative considerations underlying the choice of animal species and strains in different research disciples. Each chapter focuses on an important subdiscipline and can be read and used as a stand-alone text. This reader-friendly handbook stresses the 3Rs: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize the discomfort experienced by the animal participants. Catalog no. 84577, ISBN: 978-1-4200-8457-3 April 2011, 7 x 10, 480 pp. Suggested Price: $119.95 / £76.99 Also available as an eBook

The IACUC Handbook Second Edition Edited by

Jerald Silverman University of Massachusetts Medical School, Worcester, USA

Mark A. Suckow University of Notre Dame, Indiana, USA

Sreekant Murthy Drexel University, Philadelphia, Pennsylvania, USA

Since its establishment by USDA regulation in the 1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premiere US instrument for animal welfare supervision. The IACUC Handbook provides a foundation for those attempting to understand and implement the various responsibilities of this committee. This new edition features comprehensive updates for all pertinent federal laws, regulations, and policies. It incorporates revised suggestions on bestpractice compliance from experienced professionals. With concise, easy-to-find information, it remains the reference of choice for researchers and professionals. Catalog no. 4010, ISBN: 978-0-8493-4010-9 October 2006, 7 x 10, 680 pp. Suggested Price: $89.95 / £57.99

Lab Animal Science

The Laboratory Zebrafish

Handbook of Laboratory Animal Science Third Edition, Volume III Animal Models Edited by

Jann Hau and Steven J. Schapiro Building upon the success of the bestselling Handbook of Laboratory Animal Science and complementing Volumes I and II of the third edition, this new volume will complete the task of providing a comprehensive overview of animal models in all biomedical disciplines. The book covers most of the important lab animal science bases. As with Volume II, the book focuses on the pertinent comparative aspects of the many different contexts in which animals are used as well as on the spontaneous genetic mutants and the genetically modified animal models available within different research areas. Catalog no. K15351, ISBN: 978-1-4665-5512-9 June 2013, 7 x 10, 384 pp. Suggested Price: $119.95 / £76.99 Also available as an eBook

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49


Infectious Diseases and Pathology of Reptiles Color Atlas and Text

Edited by

Owen P. Green

Edited by

Elliott T. Jacobson

WIL Research Laboratories, LLC

Lab Animal Science

University of Florida College of Veterinary Medicine, Gainesville, USA

Guy Healing

Featuring 1,200 high-quality, color photos of normal anatomy and histology, as well as gross, light, and electron microscopic images of pathogens and diseases, this exceptionally comprehensive atlas provides definitive information on every known infectious disease affecting reptiles. Beginning with a thorough review of reptile biology, anatomy, and histology, leading authorities then address specific topics such as immunology, circulating inflammatory cells, necropsy techniques, pathogen identification and isolation, molecular diagnosis, and serodiagnostics. The atlas also catalogs specific pathologies due to viruses, bacteria, fungi, and parasites.

With the evolution of vascular infusion technology, its use in the preclinical safety assessment of pharmaceuticals has become increasingly widespread. Hence, a need has developed for a single source on the scientific principles behind this technology. A logical companion to the new edition of The Techniques of NonClinical Vascular Infusion Technology, this book brings together current knowledge and underlying practices from around the world to help refine the procedures and enhance the global understanding of infusion technology.

Catalog no. 2321, ISBN: 978-0-8493-2321-8 April 2007, 8-1/2 x 11, 736 pp. Suggested Price: $209.95 / £134.00

AstraZeneca, Cheshire, UK

Catalog no. K13453, ISBN: 978-1-4398-7449-3 June 2013, 7 x 10, 320 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Also available as an eBook

Angela Courtney

Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix jacchus)

University of California, Davis, USA

Craig D. Hardman and Ken W. S. Ashwell

Pocket Handbook of Nonhuman Primate Clinical Medicine Edited by

An easy-to-understand pocket manual, this indispensible reference compiles key and important clinical medical information unique to the rhesus macaque and the cynomolgus macaque. The chapter authors denote specific treatments for other nonhuman primate species where applicable. Practical and user-friendly, this book mirrors the knowledge gained by completing a residency in clinical primate medicine. It provides formulary and drug dosages, special precautions, and important notations. It discusses diseases and clinical problems and outlines treatment based on current medicine and explains common procedures with full-color illustrations for quick reference.

50

The Science of Non-Clinical Vascular Infusion Technology

Catalog no. K13021, ISBN: 978-1-4398-6728-0 November 2012, 6-1/8 x 9-1/4, 251 pp., Soft Cover Suggested Price: $99.95 / £63.99 Also available as an eBook

The Science and Techniques of Non-Clinical Vascular Infusion Technology Two-Volume Set Edited by

Guy Healing AstraZeneca, Cheshire, UK

Owen Green WIL Research Laboratories, LLC

This two-volume set contains two books: The Techniques of Non-Clinical Vascular Infusion Technology, Second Edition and The Science of Non-Clinical Vascular Infusion Technology. The first volume provides complete instructions for a wide range of infusion techniques delivered to multiple species. With sections devoted to rats, mice, rabbits, dogs, minipigs, nonhuman primates, and juvenile animals, this thorough text gives step-by-step instructions for the use of a variety of techniques and equipment. The second volume brings together the knowledge underlying practices from around the world to help refine the procedures and enhance the understanding of infusion technology. Catalog no. K13447, ISBN: 978-1-4398-7440-0 July 2013, 7 x 10, 704 pp. Suggested Price: $199.95 / £127.00

University of New South Wales, Sydney, Australia

Written for international neuroscientists engaged in research of neurological disorders such as Parkinson’s disease, Multiple Sclerosis, and Alzheimer’s disease, as well as professionals working in laboratories conducting pharmacokinetic studies, this book is the first comprehensive stereotaxic atlas of all parts of the marmoset brain, including up-to-date data on cortical areas. The atlas provides precise stereotaxic co-ordinates, functionally important chemoarchitectural information, and estimates for the numbers of neurons within important brain regions and nuclei. It also provides information for assessing the efficacy of treatments in marmoset models. Catalog no. K11718, ISBN: 978-1-4398-3778-8 January 2012, 8-1/2 x 11, 515 pp. Suggested Price: $179.95 / £114.00 Also available as an eBook

Suturing Principles in Laboratory Animal Surgery John J. Bogdanske, Scott Hubbard-Van Stelle, Margaret Rankin Riley, and Beth M. Schiffman Research Animal Resources Center (RARC), University of Wisconsin, Madison, USA

This color book and accompanying DVD introduce the basic principles of suturing and wound closure to laboratory animal technicians and staff performing surgery on research animals. They can also be used in a veterinary setting. The book and DVD provide descriptions, pictures, and videos depicting the importance of proper tissue and aseptic technique during wound closure, holding and handling of instruments, and needle placement on the needle driver. They also offer guidance on choice of needle and suture material, vessel ligation, the use of tissue staples, and more. Catalog no. K15275, ISBN: 978-1-4665-5343-9 April 2013, 6-1/8 x 9-1/4, 104 pp., Soft Cover Suggested Price: $59.95 / £38.99

Also available as an eBook

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Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition

Handbook of Microbiological Media

Edited by

Fourth Edition

M. Michael Swindle

Ronald M. Atlas

Medical University of South Carolina, Charleston, USA

University of Louisville, Kentucky, USA

To diminish the learning curve associated with using swine as models, this book provides practical technical information for the use of swine in biomedical research. It focuses on models produced by surgical and other invasive procedures, supplying the basic principles for performing experiments with an organ or system of interest. This edition contains never-before-published images, new chapters on toxicology and radiobiology, updated sections on anesthesia and perioperative care, and expanded details on anatomy and endoscopy. It also includes an accompanying DVD with 3-D, full-color images.

The latest edition of a bestseller, this updated volume lists the formulation, method of preparation, and uses for over 4,000 microbiological media. With 30 percent more entries than the previous editions, the book includes recent information on international collection of microorganisms and expanded information on yeast, algae, and Archaea. The book also contains formulations and uses of media for isolation, culture, identification, and maintenance of microorganisms. The entries are arranged alphabetically by medium name and include synonyms, sources, trademarks, and more.

Catalog no. 9278, ISBN: 978-0-8493-9278-8 March 2007, 7 x 10, 496 pp. Suggested Price: $159.95 / £102.00

Catalog no. K10224, ISBN: 978-1-4398-0406-3 March 2010, 8-1/2 x 11, 2040 pp. Suggested Price: $219.95 / £140.00

Also available as an eBook

Also available as an eBook

The Techniques of Non-Clinical Vascular Infusion Technology AstraZeneca, Cheshire, UK

Laboratory Biosecurity Handbook

Owen P. Green

Reynolds M. Salerno and Jennifer Gaudioso

Edited by

Guy Healing

WIL Research Laboratories, LLC

Sandia National Laboratories, Albuquerque, New Mexico, USA

Following in the footsteps of the original Handbook of Pre-clinical Continuous Intravenous Infusion, this completely revised edition answers the needs of researchers and technicians by providing step-by-step instructions for a wide range of infusion techniques delivered to multiple species. With sections devoted to rats, mice, rabbits, dogs, minipigs, nonhuman primates, and juvenile animals, this thorough text includes procedures for multidose infusion toxicity and reproductive toxicology studies and provides guidance on the use of a variety of equipment, including tail cuffs, harnesses, and implanted buttons. It is a companion to The Science of Non-Clinical Vascular Infusion Technology.

In recognition of the vital need to protect legitimate facilities from the theft and misuse of dangerous pathogens and toxins, the Laboratory Biosecurity Handbook serves as a guide to the implementation of pathogen protection programs. The first sections of the book offer an historical overview of biological weapons activity, key principles of biosecurity and its integration into existing frameworks, and a discussion of biosecurity risk. Later sections discuss biosecurity risk assessments, describe detailed components of a biosecurity program, and offer a graded approach to biosecurity through multiple risk levels. The book also covers risk prioritization of biological assets and biosecurity training.

Catalog no. K13451, ISBN: 978-1-4398-7445-5 July 2013, 7 x 10, 384 pp. Suggested Price: $119.95 / £76.99

Catalog no. 6475, ISBN: 978-0-8493-6475-4 June 2007, 6 x 9, 208 pp. Suggested Price: $125.95 / £79.99

Also available as an eBook

Also available as an eBook

Manipulative Tenants Fermentation Microbiology and Biotechnology

Bacteria Associated with Arthropods Edited by

Third Edition

Einat Zchori-Fein

Edited by

Kostas Bourtzis

Agricultural Research Organization, Ramat Yishay, Israel

E.M.T. El-Mansi, C.F.A. Bryce, A.L. Demain, and A.R. Allman Exploring the diverse array of metabolic pathways employed for the production of primary and secondary metabolites and biopharmaceuticals, this updated edition addresses the whole spectrum of fermentation biotechnology, from fermentation kinetics and dynamics to protein and co-factor engineering. The third edition builds upon the fine pedigree of its earlier predecessors and extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area. Four new chapters are included: Functional Genomics, SolidState Fermentations, Applications of Metabolomics to Microbial Cell Factories, and Current Trends in Culturing Complex Plant Tissues for the Production of Metabolites and Elite Genotypes. Catalog no. K12604, ISBN: 978-1-4398-5579-9 December 2011, 7 x 10, 555 pp. Suggested Price: $139.95 / £89.00

University of Western Greece, Agrinio, Greece Series: Frontiers in Microbiology

Summarizing the most up-to-date information available on bacterial symbionts of arthropods, this text provides an overview of primary symbionts as well as the most abundant secondary symbionts known to date. To encourage the integration of theory and practice in efforts to find innovative routes to pest and disease management, the editors bring together entomologists and microbiologists to create a full picture of the complex systems. Including diagrams, tables, graphs, pictures, and chemical structures, the text offers comprehensive information and a unique perspective on a fast-growing field. Catalog no. K11358, ISBN: 978-1-4398-2749-9 July 2011, 6-1/8 x 9-1/4, 306 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

Lab Animal Science / Microbiology

Swine in the Laboratory

51


Microbial Limit and Bioburden Tests

Research and Advances

Lucia Clontz

Vincent Béringue

Diosynth Biotechnology, Schering-Plough, Morrisville, North Carolina, USA

Microbiology / Molecular Biology 52

Prion Biology

Validation Approaches and Global Requirements, Second Edition

Edited by

Institut National de la Recherche Agronomique (INRA), Jouy-enJosas, France

Considered the “industry bible,” Microbial Limit and Bioburden Tests: Validation Approaches and Global Requirements provides a practical guide to microbial limit methodologies. Substantially updated and expanded to include the most recent microbial limit tests and bioburden testing mandated by USP-NF, this comprehensive second edition reflects current industry standards, regulatory expectations, and the latest technical and scientific information. It addresses new topics such as water testing and includes new chapters that provide complete coverage of biofilms, environmental monitoring, and microbial identification.

This book contains a selection of chapters aimed to provide a better understanding prion structure and biology. Together these chapters provide an overview of prion biology and underscore some of the challenges we face if we want to understand how this lively pathogen propagates and evolves in mammals. There is also mounting evidence that studying prion biology has a wider relevance due to similarities in the processes of protein misfolding and aggregation between prion disorders and other neurodegenerative disorders such as Alzheimer’s, Parkinson’s, and Huntington’s diseases.

Catalog no. 53485, ISBN: 978-1-4200-5348-7 October 2008, 6-1/8 x 9-1/4, 280 pp. Suggested Price: $219.95 / £140.00

Catalog no. N10731, ISBN: 978-1-926895-37-6 January 2013, 6.02 x 9.25, 300 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

Also available as an eBook

Molecular Detection of Human Bacterial Pathogens

Recent Advances in Microbiology

Edited by

Edited by

Dongyou Liu

Dana M. Santos

RCPA Biosecurity QAP, New South Wales, Australia

Binghamton University, New York, USA

The second book in a four-part series, this text is an in-depth review of stateof-the-art molecular detection and identification methods for human bacterial pathogens. Written by scientists with extensive expertise in human pathogen research, this book is an authoritative summary of biology, epidemiology, and pathogenesis of major human bacterial pathogens. A handy textbook for undergraduate and graduate students in medical, veterinary, and food microbiology, it contains approximately 750 figures and 750 tables for better comprehension. Topics include classification, morphology and biology, epidemiology, genomics, and diagnoses.

Microbiology is the study of microorganisms (or microbes), which include bacteria, viruses, fungi, parasites, and even prions. In short, microbiology refers to the study of life and organisms that are too small to be seen with the naked eye. Microorganisms are found in almost every habitat present in nature and are vital to humans and the environment. While some microbes are harmful, causing diseases that harm and kill people, animals, and plants, they are exploited by researchers. They have uses in food, water treatment, science and medicine, energy, warfare, and much more. This new book presents a collection of new research and studies covering advances in microbiology dealing with medicine, agriculture, and more.

Catalog no. K10625, ISBN: 978-1-4398-1238-9 April 2011, 8-1/2 x 11, 1278 pp. Suggested Price: $209.95 / £134.00 Also available as an eBook

Catalog no. N10602, ISBN: 978-1-926692-71-5 December 2011, 6-1/8 x 9-1/4, 292 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Molecular Detection of Human Fungal Pathogens Edited by

Chemical Modification of Biological Polymers

Dongyou Liu

Roger L. Lundblad

RCPA Biosecurity QAP, New South Wales, Australia

Lundblad Biotechnology, Chapel Hill, North Carolina, USA

The large number of molecular protocols available creates a dilemma for those attempting to adopt the most appropriate for streamlined identification and detection of fungal pathogens of interest. This volume contains expert contributions from international mycologists involved in fungal pathogen research and diagnosis. Following a similar format throughout, each chapter comprises a review of the classification, epidemiology, clinical features, and diagnosis of one or a group of related fungal species; an outline of clinical sample collection and preparation procedures; a selection of representative stepwise molecular detection protocols; and a discussion on further research requirements for improving the diagnosis.

Examining the chemical modification of biological polymers and the emerging applications of this technology in the field of biotechnology, this book reflects the change in emphasis from the study of protein structure/function toward applications in therapeutics and diagnostics. It begins with a review of the basic science involved, including the underlying organic chemistry, the use of various chemical reagents, and the chemical modification of nucleic acids, carbohydrates, and proteins. It then discusses the characterization of non-enzymatic chemical modification of biopolymers and the use of chemical modification to produce biotechnology products.

Catalog no. K10626, ISBN: 978-1-4398-1240-2 June 2011, 8-1/2 x 11, 958 pp. Suggested Price: $209.95 / £134.00

Catalog no. K12213, ISBN: 978-1-4398-4898-2 September 2011, 6-1/8 x 9-1/4, 426 pp. Suggested Price: $157.95 / £101.00 Also available as an eBook

Also available as an eBook

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Chronic Inflammation Edited by

Vitamin-Binding Proteins

Sashwati Roy

Functional Consequences

Ohio State University Medical Center, Columbus, USA

Debasis Bagchi University of Houston College of Pharmacy, Texas, USA

Siba P. Raychaudhuri University of California, Davis, USA and VA Medical Center Sacramento, California, USA

Designed to target scientists as well as clinicians, this book provides critical understanding of the key checkpoints that regulate chronic inflammation— which is associated with numerous chronic diseases and disorders, including autoimmune diseases, atherosclerosis, cancer, diabetes, high blood pressure, and obesity. The text provides a comprehensive understanding of the epidemiology of chronic inflammation, as well as novel regulatory mechanisms controlling inflammation initiation, progression, and resolution. The authors address pathologies associated with inflammation and provide various nutritional and therapeutic interventions for inflammatory diseases. Catalog no. K13315, ISBN: 978-1-4398-7211-6 September 2012, 7 x 10, 472 pp. Suggested Price: $139.95 / £89.00

Edited by

Krishnamurti Dakshinamurti and Shyamala Dakshinamurti Vitamins are essential micronutrients possessing a diverse chemical nature required by humans. Minor changes in the chemical structure of vitamins can cause major differences in their binding to proteins and, therefore, in their biological function. This book summarizes the current knowledge base with regard to vitamin-binding proteins. The text stresses the ways in which vitamin bonds to proteins offer therapeutic potential for various diseases. Using a systems-based approach, the authors cover such topics as vitamins and the immune system, metabolic aspects of diabetes and the cardiovascular system, neuroprotection, antioxidant function, gene regulation, and transport as a tool for tumor targeting. Catalog no. K13765, ISBN: 978-1-4398-8016-6 April 2013, 6-1/8 x 9-1/4, 360 pp. Suggested Price: $119.95 / £76.99 Also available as an eBook

Also available as an eBook

The Functional Fold Amyloid Structures in Nature Edited by

Advances in Cognitive Engineering and Neuroergonomics Edited by

Molecular Biology / Neuroscience

Molecular Pathophysiology, Nutritional and Therapeutic Interventions

Kay M. Stanney and Kelly S. Hale

Suzi Jarvis and Anika Mostaert

Design Interactive Inc., Florida, USA

Trinity College, Dublin, Ireland

Advances in Human Factors and Ergonomics Series

Bringing together a wide variety of examples of functional amyloid in a single volume, this book explores the importance of amyloid fibrils in fungi, bacteria, algae, invertebrate, and vertebrate animals for providing environmental protection, structural integrity, and regulating biochemical processes. It highlights many of the extraordinary examples of functional amyloid found to date. It provides an exciting perspective for the study of amyloid deposits as important and useful protein structures widespread in nature. Catalog no. N10462, ISBN: 978-981-4267-40-3 August 2012, 6 x 9, 184 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Nutritional Genomics

This volume explores cognitive ergonomics, which is concerned with mental processes—otherwise known as brain work. It discusses perception, memory, reasoning, and motor response, as they affect interactions among humans and other elements of a system. Topics include mental workload, decision-making, skilled performance, human-computer interaction, human reliability, work stress, and training as these relate to human-system design. Catalog no. K13224, ISBN: 978-1-4398-7016-7 July 2012, 6-1/8 x 9-1/4, 328 pp. Suggested Price: $79.95 / £49.99 Also available as an eBook

Edited by

Advances in Russian and International Neurotechnology

Wayne R. Bidlack

Edited by

California State Polytechnic University, Pomona, USA

Chris Forsythe, Mikhail V. Zotov, Gabriel A. Radvansky, and Larisa Tsvetkova

The Impact of Dietary Regulation of Gene Function on Human Disease

Raymond L. Rodriguez University of California, Davis, USA

Series: Advances in Neurotechnology

Discussing the current status of nutritional genomic research, this book contains the latest scientific findings on the mechanisms underlying diet-genome interactions. With contributions from renowned experts, it covers information on how dietary signals are transformed into disease-preventing changes in gene expression, gene-linked networks of chronic disease and cancer, and the role of food science and nutrition to meet individual genomic health needs. The book identifies future directions for research and highlights opportunities for improving global health and wellness by preventing, delaying, or mitigating chronic diseases with diet.

A summary of research by scientists in the field of cognitive neuroscience from outside the United States and Western Europe, this book offers a perspective on how international studies and developments in neurotechnology are impacted by the social foundations of the human condition. While focusing on Russian research, the book also presents research from China, India, and Brazil to describe how social foundations give rise to different moral issues and legal considerations. Chapters are grouped into topical sections that describe theoretical and technical programs of research. Each section includes commentary on ethical, legal, and social considerations.

Catalog no. K11975, ISBN: 978-1-4398-4452-6 December 2011, 7 x 10, 448 pp. Suggested Price: $139.95 / £89.00

Catalog no. K11927, ISBN: 978-1-4398-4144-0 April 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $119.95 / £76.99

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Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

53


Alzheimer’s Disease Targets for New Clinical Diagnostic and Therapeutic Strategies

Augmenting Cognition

Edited by

Edited by

Renee D. Wegrzyn PhD, Adlyfe, Inc., Rockville, Maryland, USA

Alan S. Rudolph PhD, MBA, Center for Neuroengineering, Duke University, Durham, North Carolina, USA Series: Frontiers in Neuroscience

Neuroscience

In recent years, a tremendous amount of effort has been focused on better understanding the fundamentals of Alzheimer’s disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. This volume provides a detailed synopsis of the current state of the art of diagnostics and therapeutics and identifies emerging technologies and molecules that show promise in the management and treatment of AD. Examining current hypotheses and suggesting possible new approaches to therapeutic clinical applications, this volume paves the way for a robust pipeline of therapeutics to combat not only AD, but a whole host of other neurodegenerative diseases. Catalog no. K11334, ISBN: 978-1-4398-2708-6 April 2012, 6-1/8 x 9-1/4, 298 pp. Suggested Price: $149.95 / £95.00

The Hebrew University, Jerusalem, Israel

Henry Markram Swiss Federal Institute of Technology, Lausanne, Switzerland

Augmenting cognition is a rapidly emerging field in neuroscience, concerned with the translation of what is known about cognitive function and dysfunction to engineer approaches to enhance and rehabilitate the brain. Modern medicine has few options to treat those with cognitive deficiencies, and as we learn more about the biology of these conditions, we consider the design of a new class of therapies to restore and augment cognition. This book describes a number of the foundational areas of cognitive enhancement, with chapters devoted to the following subject areas: use of stem cells, savants, post-traumatic stress disorder, deep-brain stimulation, music and dance, virtual reality, role of sleep, longevity, drugs, and the brain-computer interface. Catalog no. N10260, ISBN: 978-1-4398-3993-5 November 2011, 6 x 9, 250 pp. Suggested Price: $89.95 / £57.99

Also available as an eBook

Astrocytes Wiring the Brain Edited by

Eliana Scemes and David C. Spray Albert Einstein College of Medicine, Bronx, New York, USA Series: Frontiers in Neuroscience

54

Idan Segev

Astrocytes play diverse roles in central nervous system (CNS) function and dysfunction, and the connections that the astrocyte makes with other cells of the brain are essential for a variety of important neural tasks. This volume emphasizes cellular connections and surveys the most current findings on astrocyte activity. The book identifies major astrocyte biomarkers and describes how they define the different connectivity domains. It examines the role of these connections and explains how their function can be manipulated and how dysfunction of the connectivity leads to aberrant brain performance. The final section explores the alterations of glia that have been observed in specific diseases of the brain. Catalog no. K11240, ISBN: 978-1-4398-2584-6 November 2011, 6-1/8 x 9-1/4, 440 pp. Suggested Price: $149.95 / £101.00 Also available as an eBook

Chemotherapy-Induced Neuropathic Pain Edited by

Robert B. Raffa, Richard Langford, Joseph V. Pergolizzi, Jr., Frank Porreca, and Ronald J. Tallarida Written for pain management practitioners, oncologists, pharmacologists, and primary care practitioners, as well as students in these fields, this reference provides insight into the chemotherapy-induced neuropathic pain that a significant number of cancer survivors suffer. It reviews the basic and clinical research into the normal physiology of pain transmission pathways, neuropathic pain pathology, the chemotherapeutic drug mechanisms of action and adverse effects, chemotherapy-induced neuropathy, and drug discovery efforts for treatment. This reference covers both basic science and clinical research, providing a unique insight into drug discovery efforts. Catalog no. K12881, ISBN: 978-1-4398-6218-6 July 2012, 6-1/8 x 9-1/4, 233 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Computational Neuroscience Simulated Demyelinating Neuropathies and Neuronopathies

Atlas of the Neonatal Rat Brain Renuka Ramachandra and Thyagarajan Subramanian

Diana Ivanova Stephanova Institute of Biophysics and Biomedical Engineering, Sofia, Bulgaria

Bozhidar Dimitrov Kolev Institute for Population and Human Studies, Sofia, Bulgaria

The first histological atlas of the rat neonatal brain, this volume provides researchers in neurology, pharmacology, biology, and veterinary science with detailed color images of the normal developing rat brain. Each plate is a photomicrograph composite that shows the entire brain in sagittal and coronal sections at each stage and stained with cresyl violet. Various brain nuclei and their connections are specifically labeled. Since changes in the rat brain postbirth are so rapid, images are provided for postnatal days one, five, and fifteen.

This book covers the computer simulation of demyelinating neuropathies and neuronopathies and compares models with clinical findings. Through the approximation of nerve excitation and conduction, the authors show how the versatile structure of nerve fibers relates to different modes of focal prospects, inward and outward currents, conduction velocity, and errant transmission. They also explain how mathematical models elucidate emerging fine distinctions between hereditary and acquired neuronal diseases, including Charcot-MarieTooth, chronic inflammatory demyelinating polyneuropathy, Guillain-Barre syndrome, multifocal motor neuropathy, and amyotrophic lateral sclerosis.

Catalog no. K11857, ISBN: 978-1-4398-4012-2 January 2011, 8-1/2 x 11, 188 pp. Suggested Price: $167.95 / £107.00

Catalog no. K16831, ISBN: 978-1-4665-7832-6 January 2013, 6-1/8 x 9-1/4, 150 pp. Suggested Price: $69.95 / £44.99

Also available as an eBook

Also available as an eBook

The Pennsylvania State University Hershey Medical Center, USA

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Neurobehavioral Impairment and Maladaptation, Second Edition Rolland S. Parker

Edited by

André Mercanzini Faculty of Engineering, Swiss Federal Institute of Technology Lausanne, (EPFL), Switzerland

New York University School of Medicine, New York, USA

Philippe Renaud

Continuing the tradition of the bestselling first edition, this second edition provides comprehensive coverage of neurobehavioral disorders in children and adults following impact and acceleration accidents. Completely revised and updated, the book includes comprehensive coverage of consciousness including normal, acute, and persistent alterations. Drawing on his training, education, and experience in human physiology, neuroanatomy, and endocrinology, the author not only gives readers a solid foundation for understanding, diagnosing, and treating concussive brain trauma, but also gives them tools to increase standards of care.

Despite their demonstrated effectiveness, the long-term use of microscale neuroprosthetic devices is compromised by the post-implantation tissue reaction that often forms around the device. This book studies ways to improve the tissue reaction to implanted neuroprosthesis by use of a controlled drug release mechanism, quantified by novel measurement techniques. The author describes solutions to the problem of tissue reaction around microscale neuroprostheses and also examines an improvement in neural stimulation and recording capability. The author, Andre Mercanzini is review editor for Frontiers in Neuroengineering. He holds two U.S. patents on microassembly.

Catalog no. 8039, ISBN: 978-0-8493-8039-6 September 2011, 7 x 10, 879 pp. Suggested Price: $167.95 / £107.00

Catalog no. N10256, ISBN: 978-1-4398-3754-2 January 2011, 6 x 9, 250 pp. Suggested Price: $89.95 / £57.99

Also available as an eBook

Dopamine-Glutamate Interactions in the Basal Ganglia

Neuroscience

Concussive Brain Trauma

Microfabricated Cortical Neuroprostheses

Nanoneurosurgery Edited by

Edited by

Babak Kateb

Susan Jones

Cedars Sinai Medical Center, West Hollywood, California, USA

University of Cambridge, UK

John D. Heiss

Series: Frontiers in Neuroscience

National Institute of Health, Bethesda, Maryland, USA

The basal ganglia are involved in complex brain functions and are implicated in numerous neurological and psychiatric disorders. At the heart of both function and dysfunction of basal ganglia circuits is the interaction of dopamine and glutamate. Improved labeling, imaging, recording, and genetic manipulation approaches have yielded new information on how dopamine and glutamate interact to generate the circuit activity underpinning basal ganglia function. This volume synthesizes this research, presenting current insights on individual neurons and synapses, detailed circuit analysis, and learning and action functions of the basal ganglia. The book also discusses compromised dopamine-glutamate interaction in various disorders of basal ganglia function.

Reviewing the state of the nanoneurosurgery field, this book provides current information about nanoplatforms and their use in neurosurgery, neurology, neuroscience, and neuroradiology. It focuses on the educational gap across different disciplines, emphasizing the importance of integrating nanotechnology into clinical neurosurgery, neurology, neuroscience, and radiology/medicine. The authors cover currently available nanoplatforms developed for cancer imaging, drug delivery, and therapeutics as well as traumatic brain injury and neurodegenerative disorders. The text also provides links to online videos illustrating the different nanoplatforms that are being used in vivo and in vitro.

Catalog no. 88793, ISBN: 978-1-4200-8879-3 December 2011, 6-1/8 x 9-1/4, 284 pp. Suggested Price: $149.95 / £101.00

Catalog no. K12237, ISBN: 978-1-4398-4941-5 May 2013, 7 x 10, 656 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Also available as an eBook

Epilepsy The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics

The Neurobiological Basis of Suicide

Edited by

Yogesh Dwivedi

Ivan Osorio, Hitten P. Zaveri, Mark G. Frei, and Susan Arthurs Integrating the studies of epilepsy, neurosciences, computational neurosciences, mathematics, physics, engineering, and medicine, this volume provides the first means to a clear, structured, and enriching multidisciplinary perspective for developing students, researchers, and clinicians in the field of epilepsy. The text gives up-to-date information on the state of current research, possible future research, and clinical directions in the fields of epilepsy and seizure dynamics. Clear illustrations that illustrate the patterns of brain electrophysiology and behavioral manifestations are provided to aid comprehension. The authors include extensive references in each chapter to enhance further study. Figure slides are available upon qualifying course adoption

Catalog no. K11766, ISBN: 978-1-4398-3885-3 May 2011, 7 x 10, 546 pp. Suggested Price: $199.95 / £127.00

Edited by

University of Illinois at Chicago, USA Series: Frontiers in Neuroscience

Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of less clinical use. With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding the suicide pathophysiology. The Neurobiological Basis of Suicide discusses how and why neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications. Catalog no. K11764, ISBN: 978-1-4398-3881-5 June 2012, 6-1/8 x 9-1/4, 482 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Also available as an eBook

For more information and a complete list of titles, visit us at www.crcpress.com

55


Edited by

Neurons and the DHA Principle

Francisco Lopez-Muñoz

Raymond C. Valentine

Neurobiology of Depression University of Alcalá, Madrid, Spain and Camilo José Cela University, Madrid, Spain

Cecilio Alamo

University of California at Davis, USA Professor Emeritus, UC Davis and Visiting Scholar, University of California, Santa Barbara, USA

University of Alcalá, Madrid, Spain

David L. Valentine

Neuroscience

Series: Frontiers in Neuroscience

University of California, Santa Barbara, USA

With excerpts from international specialists in the field of neurobiology, this book presents state-of-the-art research on the neurobiological aspects of depression. It discusses opioid and endocannabinoid systems and depression and explores other sources for depression provided by research in biochemistry, molecular biology, and genomics. Topics covered include genetic factors of depression; monoaminergic pathways and depression; serotonergic pathways and depression; melantonergic system, chronobiological rhythms, and depression; the significance of tachykinin mechanisms in depression; and the melatonergic system, chronobiological rhythms, and depression. This book serves as a reference for researchers in neuroscience and related fields, as well as graduate students.

Recent discoveries have highlighted the role of omega-3 fatty acid DHA in brain health and degeneration as well as the molecular biology of this fatty acid in neurons. Neurons and the DHA Principle explores this duality, proposing a new model for the cause of Alzheimer’s disease and other neurodegenerative disorders, in which DHA-enriched membranes of neurons become dysfunctional and energetically wasteful, triggering premature death of neurons. Using examples from the world of animal cells, the book illustrates how DHA acts both as an essential building block of neurons while also conspiring for their assassination during aging.

Catalog no. K11746, ISBN: 978-1-4398-3849-5 September 2011, 7 x 10, 522 pp. Suggested Price: $149.95 / £101.00

Catalog no. K13471, ISBN: 978-1-4398-7486-8 November 2012, 6-1/8 x 9-1/4, 287 pp. Suggested Price: $159.95 / £95.00 Also available as an eBook

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Neurotechnology Neurobiology of Sensation and Reward Edited by

Jay A. Gottfried Northwestern University, Chicago, Illinois, USA

56

Premises, Potential, and Problems Edited by

James Giordano Center for Neurotechnology Studies, Potomac Institute for Policy Studies, Arlington, Virginia, USA and Human Science Center, Ludwig-Maximilians University, Munich, Germany

Series: Frontiers in Neuroscience

Series: Advances in Neurotechnology

A comprehensive systems overview of sensory and reward processing in the brain, this book explores what reward processing can teach us about the senses and what sensory processing can teach us about reward. In examining this neurobiological interface, the book reveals how the intrinsic properties of sensory systems effectively define and constrain the ambitions of reward-related processing in human and non-human brains. With contributions from leading investigators in the fields of sensation and reward, the text injects the “sensory” back into the study of reward processing, and the “rewarding” back into the study of sensory processing.

New technologies that allow us to investigate mechanisms and functions of the brain have shown considerable promise in treating brain disease and injury. These emerging technologies also provide a means to assess and manipulate human consciousness, cognitions, emotions, and behaviors, bringing with them the potential to transform society. This volume explores the technical, moral, legal, and sociopolitical issues that arise in and from today’s applications of neuroscience and technology and discusses their implications for the future. Topics discussed include neurotechnology in education, neuroimaging and tissue implantation technology neuroprostheses, cyborg technology, and more.

Catalog no. 67265, ISBN: 978-1-4200-6726-2 March 2011, 7 x 10, 466 pp. Suggested Price: $149.95 / £101.00

Catalog no. K11241, ISBN: 978-1-4398-2586-0 April 2012, 6-1/8 x 9-1/4, 354 pp. Suggested Price: $119.95 / £76.99

Also available as an eBook

Also available as an eBook

Neuromorphic Olfaction

Parkinson’s Disease

Edited by

Second Edition

Krishna C. Persaud The University of Manchester, UK

Santiago Marco University of Barcelona, Spain

Augustin Gutierrez-Galvez University of Barcelona, Spain Series: Frontiers in Neuroengineering

Edited by

Ronald F. Pfeiffer University of Tennessee Health Science Center, Memphis, USA

Zbigniew K. Wszolek Mayo Clinic, Jacksonville, Florida, USA

Manuchair Ebadi University of North Dakota, Grand Forks, USA

With biological components of chemical sensing systems becoming well understood in terms of their structure and function, it is now possible to consider biomimetic models of olfaction and how they may be translated into functional engineering devices. This book presents an innovative interdisciplinary biomimetic approach to olfaction, including biology, hardware, software, and sensors. The text explores contributions to the realization of novel chemical sensing systems inspired by biological pathways, describing cutting-edge research such as engineering aspects of olfaction, odor coding of neurons, chemical sensor arrays, and biologically modeled sensor robots.

In recent years, considerable advances have been made in our knowledge and understanding of Parkinson’s disease (PD). In particular, there has been an explosion of information regarding genetic contributions to the etiology of PD and an increased awareness of the incidence and importance of the non-motor features of the disease. Theories regarding the pathogenesis and pathophysiology of PD have also been refined, and new treatment modalities and advances have been implemented. Reflecting these changes, this second edition features new chapters devoted to genetic aspects of PD, non-motor features of the disease, as well as aspects of the pathophysiology, pathogenesis, and treatment of PD.

Catalog no. K13286, ISBN: 978-1-4398-7171-3 March 2013, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $149.95 / £95.00

Catalog no. K10361, ISBN: 978-1-4398-0714-9 October 2012, 8-1/2 x 11, 1308 pp. Suggested Price: $249.95 / £159.00

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Edited by

Transcranial Brain Stimulation

Rodrigo Quian Quiroga

Edited by

University of Leicester, UK

Stefano Panzeri University of Glasgow, UK and Italian Institute of Technology, Asti, Italy

Written by renowned experts in the field, this book provides a comprehensive and up-to-date overview on neural coding. It describes the principles of neural coding, covers some of the major developments in this area, and presents a complete view of how neurons in the brain encode information. The text not only contains the most important experimental findings, but also gives an overview of the main methodological aspects for studying neural coding. In addition, the book describes alternative approaches based on simulations with neural networks and in silico modeling. Catalog no. K12460, ISBN: 978-1-4398-5330-6 May 2013, 7 x 10, 640 pp. Suggested Price: $179.95 / £108.00 Also available as an eBook

Carlo Miniussi, Walter Paulus, and Paolo M. Rossini Series: Frontiers in Neuroscience

Recent years have seen the introduction and rapid development of non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) and transcranial electrical stimulation. This book reviews these recent advances made in the understanding of brain stimulation techniques. The text presents the wide range of possible brain stimulation applications in combination with neuroimaging and discusses what new information can be gained from using this technique on the dynamics of brain functions, hierarchical organization, and effective connectivity. With this timely resource, the authors aim to make a substantial impact on many areas of clinical and basic neuroscience. Catalog no. K13512, ISBN: 978-1-4398-7570-4 December 2012, 6-1/8 x 9-1/4, 464 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

Spike Timing Mechanisms and Function Edited by

Patricia M. DiLorenzo

TRP Channels

Binghamton University, New York, USA

Edited by

Jonathan D. Victor

Michael X. Zhu

Weill Medical College of Cornell University, New York, New York, USA Series: Frontiers in Neuroscience

Neuronal communication forms the basis for all behavior, from the smallest movement to our grandest thought processes. Among the many mechanisms that are used in this function, spike timing is among the most powerful and, until recently, perhaps the least studied. In the last two decades, however, the study of spike timing has exploded. This book presents the function of spike timing in sensory, motor, and integrative processes. The chapters bring together the work and ideas of leaders in the field to address current thinking as well as the future of the study of spike timing. The text provides readers with a wide perspective on how spike timing is produced and used by the nervous system.

The University of Texas Health Science Center at Houston, USA Series: Methods in Signal Transduction

Providing detailed methods for the study of transient receptor potential (TRP) channels and their role in a wide variety of cellular functions, this book includes expression and functional studies of TRP channels in heterologous systems as well as structural and functional studies of TRP channels. The author also explores various methods for detailed analysis of biophysical properties of TRP channels. In addition, the text covers high-throughput screening assays for TRP channels and offers novel and effective approaches to study endogenous TRP channel function in native systems. An instructor’s manual is available upon qualifying course adoption

Catalog no. K11729, ISBN: 978-1-4398-3815-0 March 2013, 6-1/8 x 9-1/4, 500 pp. Suggested Price: $149.95 / £95.00

Catalog no. K10983, ISBN: 978-1-4398-1860-2 April 2011, 6-1/8 x 9-1/4, 499 pp. Suggested Price: $157.95 / £101.00

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Also available as an eBook

The Neural Bases of Multisensory Processes Edited by

Viral Hemorrhagic Fevers Edited by

Micah M. Murray

Sunit K. Singh

CIBM, Lausanne, Switzerland

Centre for Cellular and Molecular Biology, Hyderabad, India

Mark T. Wallace Vanderbilt Brain Institute, Nashville, Tennessee, USA

Daniel Ruzek

Series: Frontiers in Neuroscience

Biology Centre ASCR- Institute of Parasitology, Ceske Budejovice, Czech Republic

It has become accepted in the neuroscience community that perception and performance are quintessentially multisensory by nature. Using the full palette of modern brain imaging and neuroscience methods, this volume details current understanding in the neural bases for these phenomena as studied across species, stages of development, and clinical statuses.Topics discussed include anatomy, neurophysiological bases and how multisensory stimuli can dramatically change the encoding processes for sensory information, combinatorial principles and modeling, development and plasticity, clinical manifestations, how perception and action are affected by altered sensory experience, and attention and spatial representations.

Viral hemorrhagic fevers (VHFs) are a group of febrile illnesses caused by RNA viruses from several viral families. These infectious viruses lead to a potentially lethal disease syndrome characterized by fever, malaise, vomiting, mucosal, and gastrointestinal bleeding, edema, and hypotension. The four viral families known to cause VHF disease in humans naturally reside in an animal reservoir host or arthropod vector. This volume presents the most current information on each virus. It examines the fevers caused by these viruses, their mechanisms for spreading, their molecular pathogenesis, host pathogen immune interactions, and detection, treatment, and prevention.

Catalog no. K10614, ISBN: 978-1-4398-1217-4 August 2011, 7 x 10, 809 pp. Suggested Price: $149.95 / £101.00 Also available as an eBook

Neuroscience

Principles of Neural Coding

Catalog no. K13962, ISBN: 978-1-4398-8429-4 June 2013, 7 x 10, 416 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

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57


Asbestos Risk Assessment, Epidemiology, and Health Effects Second Edition

Medico-Legal Case Studies

Ronald F. Dodson

Kalipatnapu N. Rao

ERI Consulting, Inc., & University of Texas at Tyler, USA

Samuel P. Hammar

Toxicology / Biopharmaceuticals

Diagnostic Specialties Laboratory, Bremerton, Washington, USA

This second edition of a bestseller provides an updated interdisciplinary text on the rapidly evolving information regarding asbestos and human health. It discusses the types of instruments and methods available for evaluation of the content of asbestiform minerals in products, air, water, surface areas, and tissue. It explains the relevance of each of these applications and gives readers the tools to evaluate data in the future. Expert contributors offer readers an overview of issues involved in exposure to asbestos. Catalog no. K10484, ISBN: 978-1-4398-0968-6 June 2011, 7 x 10, 679 pp. Suggested Price: $167.95 / £107.00 Also available as an eBook

University of Pittsburgh Medical Center, Pennsylvania, USA

Modern technology using state-of-the-art equipment can now identify almost any toxin relevant to a legal issue. Tracking the progression of toxicology findings from the laboratory to the courtroom, this volume prepares practicing toxicologists to write reports and testify at depositions and in court. Topics include determining serum/blood ethanol levels, ethylene glycol poisoning, plant and animal toxins, alcohol intoxication, synergistic effects of alcohol and drugs, prescription drug overdose, toxic torts, and workers’ compensation issues. Written in an accessible style, this volume is essential for forensic toxicologists who need to understand how to best present the science of toxicology in the forensic arena. Catalog no. K12995, ISBN: 978-1-4398-6681-8 February 2012, 6-1/8 x 9-1/4, 289 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

The Chemical Components of Tobacco and Tobacco Smoke Second Edition Alan Rodgman, Thomas A. Perfetti

58

Forensic Toxicology

Edited by

The first edition was very successful in chronicling the extraordinary progress made by scientists in the field of tobacco science from its beginnings in the early 1800s to the present. It provided over 6,000 references on more than 8,400 components identified in tobacco and tobacco smoke and examined the isolation and characterization of each component. Since the first edition, there have been over a half dozen major scientific conferences such as the Tobacco Science Research Conferences and the CORESTA Congresses in 2008, 2009, and 2010 in which many articles on tobacco and/or smoke components were presented. This second edition incorporates all this new information, including tobacco and tobacco smoke-related research, published in late 2008, 2009, and 2010. Catalog no. K15040, ISBN: 978-1-4665-1548-2 February 2013, 8-1/2 x 11, 2320 pp. Suggested Price: $299.95 / £191.00 Also available as an eBook

Handbook of Forensic Toxicology for Medical Examiners D. K. Molina, M.D. Series: Practical Aspects of Criminal & Forensic Investigations

Forensic professionals, often working through heavy caseloads, require quick and easy access to reliable sources of information to help interpret toxicology results. This volume is a concise handbook referencing the most common toxic drugs and their levels of toxicity, making it an ideal text for quick confirmation in the field or in the lab. It describes how to obtain and submit samples, explains methods of analysis, and provides hundreds of tables and data sets on substances causing toxicity that are commonly seen in forensic practice. The book includes several appendices, including one on the latest issues in pharmacogenetics pertinent to forensic investigation. Catalog no. 76418, ISBN: 978-1-4200-7641-7 July 2009, 6-1/8 x 9-1/4, 384 pp., Soft Cover Suggested Price: $99.95 / £64.99 Also available as an eBook

CRC World Dictionary of Medicinal and Poisonous Plants

Instrumental Data for Drug Analysis

Common Names, Scientific Names, Eponyms, Synonyms, and Etymology, Five-Volume Set

Third Edition 6 Volume Set

Umberto Quattrocchi

Terry Mills, III, James Conrad Roberson, Christian C. Matchett, Mathew J. Simon, Mark D. Burns, and Robert J. Ollis, Jr.

Written as a reference to be used within university, departmental, public, institutional, herbaria, and arboreta libraries, this book provides the first starting point for better access to data on medicinal and poisonous plants. Following on the success of the author’s CRC World Dictionary of Plant Names and the CRC World Dictionary of Grasses, the author provides the names of thousands of genera and species of economically important plants. It serves as an indispensable timesaving guide for all those involved with plants in medicine, food, and cultural practices as it draws on a tremendous range of primary and secondary sources. This authoritative lexicon is much more than a dictionary. It includes historical and linguistic information on botany and medicine throughout each volume.

Finding detailed information on the analysis of drug-related compounds is challenging at best. This latest edition is an extensive six-volume set that contains over 6,500 spectra on more than 1,750 illicit and prescription drugs. It presents data on the six most popular analytical techniques used today: ultraviolet (UV) spectroscopy, infrared (IR) spectrometry, nuclear magnetic resonance (NMR) spectrometry, mass spectrometry (MS), gas chromatography (GC), and high pressure liquid chromatography (HPLC). This edition also presents the latest analytical techniques of FT-Ramen Spectra. Drugs are alphabetized and a combined index permits easy reference.

Catalog no. 8044X, ISBN: 978-1-4200-8044-5 May 2012, 8-1/2 x 11, 3960 pp. Suggested Price: $1295.00 / £825.00

Catalog no. 1974, ISBN: 978-0-8493-1974-7 August 2005, 8-1/2 x 11, 4688 pp. Suggested Price: $1499.00 / £955.00

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PAT Applied in Biopharmaceutical Process Development and Manufacturing

Nonclinical Safety Assessment

An Enabling Tool for Quality-by-Design

Edited by

Edited by

Pritam S. Sahota, James A. Popp, Jerry F. Hardisty, and Chirukandath Gopinath

Cenk Undey, Duncan Low, Jose C. Menezes, and Mel Koch

Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, this book presents histopathologic descriptions of lesions noted in drug development. Each section contains information related to the lesion to assist the pathologist in making a determination of the origin of the lesion, the importance of the lesion, and the relevance for assessing human risk. Organ-based chapters include a description of light microscopic and electron microscopic of pathological lesions, differential diagnoses, and biological consequences, pathogenesis and/or mechanism of lesion formation, and expected clinical pathology correlates. Catalog no. K13314, ISBN: 978-1-4398-7210-9 March 2013, 7 x 10, 1013 pp. Suggested Price: $259.95 / £172.00 Also available as an eBook

Series: Biotechnology and Bioprocessing

This book summarizes the state of the art in process analytical technologies applied to various aspects of biopharmaceutical process development and manufacturing. The text summarizes regulatory perspectives, FDA/EMEA guidelines, and new expectations. In addition, it explores new technology, especially in the area of real-time monitoring for end-point control, as well as new sensor and analytical technologies. It details established and emerging measurement technologies, including future needs, and challenges that require further research. The authors also present successful industrial-scale deployment case studies and strategies from the biopharmaceutical industry and discuss future trends. Catalog no. K11448, ISBN: 978-1-4398-2945-5 December 2011, 6-1/8 x 9-1/4, 327 pp. Suggested Price: $167.95 / £107.00 Also available as an eBook

Applying Genomic and Proteomic Microarray Technology in Drug Discovery Second Edition Robert S. Matson Beckman Coulter, Fullerton, California, USA

Written for academics, researchers, and professionals within the field of pharmaceutical science and biology, this second edition reference highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. Continuing with the same focus as the first, this book contains updated and revised sections to meet the needs of the current market. It covers bead-based assays and the expanded role for microarrays in biomarker discovery and diagnostics. Omics-driven applications have been expanded to include chemical biology and metabolomics. A new chapter includes Multiplex Assays and its future impact on biomarket discovery, drug discovery, companion diagnostics, and personalized medicine. Catalog no. K12595, ISBN: 978-1-4398-5563-8 February 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Quality Operations Procedures for Pharmaceutical, API, and Biotechnology Syed Imtiaz Haider and Erfan Syed Asif This book classifies the various aspects of quality operations as separately designed operating procedures and provides a systematic description for each element. Addressing local and international compliance, the author presents technical solutions to fulfill the needs of quality assurance and quality control systems of all grades. The text presents standard operating procedures for documentation guidelines, validation guidelines, handling of materials in microbiological labs, process simulation testing, conducting internal audits, and chemical and biological testing. An accompanying CD-ROM offers valuable key performance indicator templates. Catalog no. K14029, ISBN: 978-1-4398-8690-8 June 2012, 7 x 10, 584 pp. Suggested Price: $129.95 / £82.00 Also available as an eBook

Cell Culture Technology for Pharmaceutical and Cell-Based Therapies Centocor Inc., Nottingham, Pennsylvania, USA

Adaptive and Flexible Clinical Trials

Wei-Shou Hu

Richard Chin

Edited by

Sadettin Ozturk

University of Minnesota, Minneapolis, USA

Institute for One World Health, San Francisco, California, USA

Series: Biotechnology and Bioprocessing

By enabling studies to be modified during the course of the trial, modern adaptive clinical trial designs can make studies substantially faster, more efficient, and more powerful than traditional clinical trials. The recent advances in webbased real-time data entry and novel statistical methods have made adaptive clinical trials practical and attractive. Suitable for readers involved in drug development, this is the first book that comprehensively explains all essential aspects of adaptive clinical trials. Without using highly technical statistical jargon, it discusses the design, conduct, and execution of these trials.

Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology development in the production of biotechnology products, tissue engineering, and cell-based therapies. Offering detailed guidance, they cover the steps leading up to the creation of viable therapies including host cell selection, cloning and gene amplification, bioreactor design and operation, protein purification, optimization, scale-up, and facility design. Catalog no. DK1481, ISBN: 978-0-8247-5334-4 August 2005, 7 x 10, 776 pp. Suggested Price: $229.95 / £146.00

Biopharmaceuticals / Clinical Trials

Toxicologic Pathology

Catalog no. K11738, ISBN: 978-1-4398-3832-7 August 2011, 6-1/8 x 9-1/4, 198 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

Also available as an eBook

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59


Adaptive Design Methods in Clinical Trials Second Edition Shein-Chung Chow

Clinical Trials / Drug Discovery and Development 60

Duke University School of Medicine, Durham, North Carolina, USA

Mark Chang AMAG Pharmaceuticals, Inc, Lexington, Massachusetts, USA Chapman & Hall/CRC Biostatistics Series

This second edition reflects recent developments and regulatory positions on the use of adaptive designs in clinical trials. It unifies the vast and continuously growing literature and research activities on regulatory requirements, scientific and practical issues, and statistical methodology. This edition significantly updates the chapters on protocol amendment and clinical trial simulation to incorporate the latest changes. It also includes five entirely new chapters on twostage adaptive design, biomarker adaptive trials, target clinical trials, sample size and power estimation, and regulatory perspectives. Catalog no. K11837, ISBN: 978-1-4398-3987-4 December 2011, 6-1/8 x 9-1/4, 374 pp. Suggested Price: $89.95 / £59.99 Also available as an eBook

Multiple Comparisons Using R Frank Bretz Novartis Pharma AG, Basel, Switzerland

Torsten Hothorn Ludwig-Maximilians-Universität München, Germany

Peter Westfall Texas Tech University, Lubbock, USA

Controlling multiplicity in experiments ensures better decision making and safeguards against false claims. Adopting a unifying theme based on maximum statistics, this self-contained introduction describes the common underlying theory of multiple comparison procedures through numerous examples. It covers a range of multiple comparison procedures, from the Bonferroni method and Simes’ test to resampling and adaptive design methods. The book also presents a detailed description of available software implementations in R. The R packages and source code for the analyses are available at http://CRAN.R-project.org Catalog no. C5742, ISBN: 978-1-58488-574-0 July 2010, 6-1/8 x 9-1/4, 205 pp. Suggested Price: $87.95 / £56.99 Also available as an eBook

Controversial Statistical Issues in Clinical Trials

Practical Guide to Clinical Data Management

Shein-Chung Chow

Third Edition

Duke University School of Medicine, Durham, North Carolina, USA

Susanne Prokscha

Chapman & Hall/CRC Biostatistics Series

Redwood City, California, USA

Written by one of the preeminent experts in the field, this book covers commonly encountered controversial statistical issues in clinical trials and, whenever possible, makes recommendations to resolve these problems. It focuses on issues occurring at various stages of clinical research and development, including early-phase clinical development, bench-to-bedside translational research, and late-phase clinical development. Numerous examples illustrate the impact of these issues on the evaluation of the safety and efficacy of the test treatment under investigation. The author also offers recommendations regarding possible resolutions of the problems.

Clinical data management (CDM) has gone from predominantly relying on the collection of data on paper forms to using electronic data capture (EDC). Today, the assumption is that a trial will be conducted using EDC and that extenuating circumstances might lead to it being conducted using paper. This third edition emphasizes the EDC process. The chapters in the text are organized to represent the main elements of CDM: study startup, study conduct, and study closeout. In addition, a new chapter on the clinical trial process explains the high level flow of a clinical trial from creation of the protocol through the study lock and provides the context for the clinical data management activities that follow.

Catalog no. K12247, ISBN: 978-1-4398-4961-3 June 2011, 6-1/8 x 9-1/4, 611 pp. Suggested Price: $99.95 / £66.99

Catalog no. K12152, ISBN: 978-1-4398-4829-6 October 2011, 6-1/8 x 9-1/4, 296 pp. Suggested Price: $149.95 / £101.00

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Randomized Clinical Trials of Nonpharmacological Treatments Edited by

Design and Analysis of Bridging Studies Edited by

Jen-pei Liu, Shein-Chung Chow, and Chin-Fu Hsiao Taking into account the International Conference Harmonisation E5 framework for bridging studies, this book covers the regulatory requirements, scientific and practical issues, and statistical methodology for designing and evaluating bridging studies and multiregional clinical trials. For bridging studies, the authors explore ethnic sensitivity, the necessity of bridging studies, types of bridging studies, and the assessment of similarity between regions based on bridging evidence. For multiregional clinical trials, the text considers regional differences, assesses the consistency of treatment effect across regions, and discusses sample size determination for each region. Catalog no. K12075, ISBN: 978-1-4398-4634-6 July 2012, 6-1/8 x 9-1/4, 287 pp. Suggested Price: $99.95 / £63.99

Isabelle Boutron INSERM U738, Paris, France

Philippe Ravaud INSERM U738, Paris, France

David Moher University of Ottawa, Ontario, Canada Chapman & Hall/CRC Biostatistics Series

Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable devices, non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. This book focuses on the methods of assessing nonpharmacological treatments, highlighting specific issues, and discussing trial design. Providing practical examples underlining the issues and solutions, this book is arguably the first exclusively explore this topic, discussing various categories of treatments, from surgical procedures to psychotherapy. Catalog no. C8017, ISBN: 978-1-4200-8801-4 December 2011, 6-1/8 x 9-1/4, 403 pp. Suggested Price: $104.95 / £66.99 Also available as an eBook

Also available as an eBook

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Drug Delivery Systems for Cardiovascular Diseases

Mohammed Reza Saboktakin

Edited by

Shobha Rani R Hiremath Al-Ameen College of Pharmacy, Bangalore, India

S. Narasimha Murthy

International Research Institute of Arian Chemie Gostar, Tabriz, Iran

The University of Mississippi, University, USA

Nanotechnology offers unique approaches to probe and control a variety of biological and medical processes that occur at nanometer length scales and is expected to have a revolutionary impact on biology and medicine. This book introduces new research on intelligent drug delivery systems for cancer therapy. The book covers recent developments in nanoparticulate drug delivery systems (NPDDS). The book then addresses the formulation of aspects covering small molecules, macromolecules, gene delivery, protein-based nanodelivery systems, therapeutic and diagnostic applications of gold nanoparticles, and the application of NPDDS in cancer, diabetes, and dermal and transdermal deliveries.

Each year, more Americans die from heart diseases than cancer, yet there is no single source that combines information about cardiovascular diseases with disease-specific drug delivery systems. This book provides an overview of existing techniques, ongoing research, and novel approaches and concepts in the treatment of cardiovascular diseases by means of novel drug delivery systems. The text covers anatomy, biochemistry, pathophysiology, and pharmacotherapy. It also addresses problems associated with therapy, reasons for non-compliance, formulation, and evaluation of drug delivery systems, as well as regulatory aspects of cardiovascular drug discovery systems.

Catalog no. N10707, ISBN: 978-1-926895-30-7 January 2013, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $149.95 / £95.00

Catalog no. K12429, ISBN: 978-1-4398-5275-0 June 2013, 6-1/8 x 9-1/4, 304 pp. Suggested Price: $149.95 / £95.00

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Also available as an eBook

Advances in Natural Medicines, Nutraceuticals and Neurocognition

Drugs of Natural Origin

Series: Drug Delivery

Edited by

A Treatise of Pharmacognosy, Sixth Revised Edition

Andrew Scholey

Gunnar Samuelsson

Swinburne University, Melbourne, Australia

Uppsala University, Sweden (retired)

Con Kerry Kenneth Stough

Lars Bohlin

Swinburne University of Technology, Hawthorne Victoria, Australia

Uppsala University, Sweden

More than half of those who see a general practitioner are taking some sort of natural medicine supplement, but little is known about the neurocognitive effects of these substances. This book examines whether natural and herbal medicines, vitamins, and supplements improve human cognition and/or brain processes in the healthy young and elderly and in disorders of cognition such as Alzheimer’s Dementia. Addressing a broad scope that includes different classes of supplements as well as different demographic groups, contributors provide a scientific focus and describe recent research as well as what is currently known about specific supplements and intelligence, memory, cognition, and brain functioning.

This sixth edition provides a multidisciplinary approach for those working in natural product development. It brings together research on the sustainable use of natural products in the development of new drugs, scientifically based herbal remedies, and environmentally adapted biomolecules. Since publication of the Fifth Edition, new concepts and techniques (genomics, proteomics, and metabolomics) have emerged, and herbal remedies have become subject to more rigid legislation aiming to improve their quality and efficacy. This development is reflected in a substantial revision and expansion of the book, which also describes many new drugs.

Catalog no. K14185, ISBN: 978-1-4398-9360-9 January 2013, 6-1/8 x 9-1/4, 371 pp. Suggested Price: $149.95 / £95.00

Catalog no. N10257, ISBN: 978-1-4398-3857-0 June 2010, 776 pp. Suggested Price: $149.95 / £95.00

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Green Tea Polyphenols Dictionary of Marine Natural Products with CD-ROM Edited by

John W. Blunt and Murray H.G. Munro

Nutraceuticals of Modern Life Edited by

Lekh R. Juneja, Mahendra P. Kapoor, Tsutomu Okubo, and Theertham Rao Taiyo Kagaku Co., Ltd., Mie, Japan

The first of its kind, this dictionary defines more than 25,000 marine natural products. It indexes each by chemical name, organism type, and compound type. Following a similar format to the Chapman & Hall Chemical Database, each entry includes biological source, chemical structure, physical properties, biological activity, and literature references. With an accompanying CD, this invaluable tool offers immediate access to information essential to the development of novel pharmaceuticals, pesticides, and marine anti-fouling agents derived from unique molecular structures of marine natural products.

Several scientific reports reveal that green tea polyphenols help reduce the risk of diseases such as cancer. This book reviews the latest evidence and pharmaceutical functions of the tea polyphenols with regard to health promotion benefits. The text discusses the rise of tea-derived supplements, which is driving the food industry and research community to address critical challenges. The authors review these challenges, which include screening the myriad of potential bioactivity of tea polyphenols, uncovering complex underpinning mechanisms, establishing optimal intake levels and synergistic formulations, and developing an adequate tea polyphenols delivery matrix.

Catalog no. 8216, ISBN: 978-0-8493-8216-1 September 2007, 8-1/2 x 11, 2536 pp. Suggested Price: $704.00 / £448.00

Catalog no. K12132, ISBN: 978-1-4398-4788-6 April 2013, 6-1/8 x 9-1/4, 280 pp. Suggested Price: $129.95 / £82.00

Also available as an eBook

Also available as an eBook

University of Canterbury, Christchurch, New Zealand

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Drug Discovery and Development

Advanced Drug Delivery Nanoparticles

61


Edited by

Neuropeptides in Neuroprotection and Neuroregeneration

Marilyn Sue Bogner

Edited by

Institute for the Study of Human Error, Bethesda, Maryland

Fred Nyberg

Human Error in Medicine Second Edition

Drug Discovery and Development

Series: Human Error and Safety

University of Uppsala, Sweden

This new edition of Human Error in Medicine presents an expanded consideration of the topic that emphasizes lessons learned not just in hospitals, but also in home and self-care— important because of the increasing prevalence of chronic illnesses. Bringing together diverse experts, the book covers a wide range of topics including errors in the use of medical equipment, errors from fatigued decision making, latent surgical errors, medical error in the legal system, and error reduction through improved technology and facility design.

With contributions from a stellar panel of experts, this book discusses neuropeptides and their role in neurodegeneration and neuroprotection. It describes important features of the endogenous neuropeptide systems regarding their formation, receptor signaling, and inactivation. It includes chapters focused on design and development of peptide-like drugs, peptidomimetics, as well as mechanisms of peptide transport over biological barriers, oxidative stress, and cognitive enhancement, all topics of enormous interest in the field.

Catalog no. ER522X, ISBN: 978-0-8058-4522-8 June 2013, 6-1/8 x 9-1/4, 368 pp., Soft Cover Suggested Price: $49.95 / £31.99

Catalog no. K11501, ISBN: 978-1-4398-3062-8 June 2012, 6-1/8 x 9-1/4, 319 pp. Suggested Price: $149.95 / £95.00

Also available as an eBook

Also available as an eBook

Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications

Obstructive Airway Diseases

Edited by

Role of Lipid Mediators

Perry G. Wang US FDA, College Park, Maryland, USA

Weixuan He Monmouth Junction, New Jersey, USA Chromatographic Science Series

62

This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President’s Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry. Catalog no. K10384, ISBN: 978-1-4398-0753-8 February 2011, 6-1/8 x 9-1/4, 610 pp. Suggested Price: $179.95 / £115.00 Also available as an eBook

Making and Using Antibodies A Practical Handbook, Second Edition Edited by

Gary C. Howard The J. David Gladstone Institutes, San Francisco, California, USA

Matthew R. Kaser Bell & Associates, San Francisco, California, USA

The second edition to a popular first, this book provides clear guidance on all aspects of how to make and use antibodies for research and commercial and industrial applications. All chapters are revised, updated, and combined or expanded. New material within this book includes scale production, recombinant methods, aptamers, antibodies as therapeutics, humanization of antibodies, and molecular imprinting. The authors present clear descriptions of basic methods for making and using antibodies, and describe basic laboratory techniques in detail. Each chapter includes introductory material, allowing for a better understanding of each concept. Practical examples are included as well. Catalog no. K13167, ISBN: 978-1-4398-6908-6 June 2013, 6-1/8 x 9-1/4, 512 pp., Soft Cover Suggested Price: $149.95 / £95.00 Also available as an eBook

Edited by

Abhijit Ray and Punit Kumar Srivastava Daiichi Sankyo Life Science Research Centre India (RCI), Gurgaon, Haryana

Incidences of inflammatory airway diseases are on the rise across the world and it is imperative that research be undertaken to discover new treatment options. This volume discusses clinically successful and potential lipid targets that can make a difference in treating some of the most intractable disease states. Topics discussed include the role of enzymes in the process of lipid mediator synthesis; the biology of arachidonic acid, platelet-activating factor, and lysophosphatidic acid; and proresolution lipid mediators in inflammatory airway disease conditions. The book also examines the role of sphingosine and ceramide in inflammatory airway disease, and protein kinases activated by lipid mediators. Catalog no. K12353, ISBN: 978-1-4398-5140-1 November 2011, 6-1/8 x 9-1/4, 381 pp. Suggested Price: $167.95 / £107.00 Also available as an eBook

Ocular Drug Delivery Systems Barriers and Application of Nanoparticulate Systems Edited by

Deepak Thassu Actavis SSL R&D, Owings Mills, Maryland, USA

Gerald J. Chader University of Southern California Medical School, Doheny Eye Institute, Los Angeles, USA

Written for academic and industrial researchers in the field of ophthalmology, this book presents research on the development of currently marketed devices and recent trends for the future delivery of drugs topically to the posterior eye. As the only book to cover drug delivery barriers and the application of nano-medicines to the eye, it includes chapters on ocular physiology and the application of nanoparticles-based delivery systems to enhance drug efficacy. Contributors include leading eye researchers, surgeons, and pharmacologists from academia, the National Eye Institute, and leading ophthalmic companies such as Pfizer, Allergan, and Novartis. Catalog no. K12138, ISBN: 978-1-4398-4800-5 October 2012, 6-1/8 x 9-1/4, 473 pp. Suggested Price: $169.95 / £108.00 Also available as an eBook

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Tools for Food Science Edited by

Application of Physical Technologies

Noureddine Benkeblia

Ajay K. Banga

University of the West Indies, Kingston, Jamaica

Mercer University, Atlanta, Georgia, USA

New discoveries in molecular biology, analytical chemistry, and biochemistry have led to the development of new tools that are likely to revolutionize the study of food. This volume examines metabolomics, metagenomics, nutrigenomics, transcriptomics, and proteomics and describes how they translate to food science research and productive technologies. The book explains how these methods can be used to assess the quality attributes of foods and food production systems. It explores the principles that regulate food production, analyzes processing and ethical issues, and documents the transformation from industrial to sustained foods production using the OMICS tools.

Interest in drug delivery systems is growing as the delivery of many drugs continues to be a problem due to safety, stability, and compliance issues. This is especially true for the increased number of biologic medicines, which include peptides, proteins, and nucleic acids. Transdermal delivery is an important part of such systems, and the use of physical enhancement methods to penetrate the skin barrier is where the field is headed. This book reviews the strategies available for the delivery of compounds into and through the skin. It also focuses on technological developments in the domain of nanotechnology that can be exploited to enhance the transdermal delivery of drugs.

Catalog no. K11677, ISBN: 978-1-4398-3706-1 January 2012, 6-1/8 x 9-1/4, 429 pp. Suggested Price: $179.95 / £114.00

Figure slides are available upon qualifying course adoption

Also available as an eBook

Catalog no. K10285, ISBN: 978-1-4398-0509-1 May 2011, 6-1/8 x 9-1/4, 309 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Pharmacogenomics of Alcohol and Drugs of Abuse Edited by

Translational Medicine The Future of Therapy Edited by

James Mittra

Amitava Dasgupta

University of Edinburgh, UK

University of Texas, Houston, USA

Christopher-Paul Milne

Loralie J. Langman

Tufts University, Medford, Massachusetts, USA

Mayo Clinic, Rochester, Minnesota, USA

Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in alcohol response is vital for professionals involved in alcohol rehabilitation programs. This volume focuses on how pharmacogenomic principles are applied to alcohol and drug testing and treatment and discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the text presents the genetic aspects of alcohol metabolism and drugs of abuse, including marijuana, cocaine, and amphetamine. It also covers methodologies in pharmacogenomic testing. Catalog no. K12633, ISBN: 978-1-4398-5611-6 April 2012, 6-1/8 x 9-1/4, 252 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM) to significantly enhance conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure/resources. In recognition of the various implications TM has for public health policy and commercial innovation, this cutting-edge, interdisciplinary book addresses the major systemic aspects of the field. This is important, because rather than focus simply on the basic science and its relation to clinical practice, the chapters in this book explore the dynamic interactions and key challenges in translating new science into viable therapies for the clinic, which crucially includes the recognition of the importance of social, commercial, and regulatory environments in addition to good science. Catalog no. N10681, ISBN: 978-981-4316-99-6 February 2013, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Topical Nail Products and Ungual Drug Delivery Edited by

S Narasimha Murthy The University of Mississippi, University, USA

Howard I. Maibach

Biopharmaceutical Supply Chains Distribution, Regulatory, Systems and Structural Changes Ahead Robert Handfield

University of California, San Francisco, USA

North Carolina State University, Raleigh, USA

Presenting crucial information on the state of the science in transungual drug delivery, this comprehensive overview provides a useful tool to assist in the development of products to treat and solve nail diseases. A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies. Discussing existing techniques, ongoing research, new approaches, and basic concepts in transungual drug delivery, this book summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.

The global pharmaceutical industry has been subjected to many challenges in the last decade, including more blockbuster drugs reaching the end of their patent life, increased regulation, pricing pressure, channel pressure, counterfeiting, and challenges in clinical trials management. This book covers the major themes and changes in the biopharmaceutical supply chain. It provides an overview of the key challenges and discusses how leading biopharma companies are dealing with these challenges. Bringing together leading researchers and industry executives, it is a must-read for those who want to learn more about achieving success in industry.

Catalog no. K10565, ISBN: 978-1-4398-1129-0 September 2012, 6-1/8 x 9-1/4, 282 pp. Suggested Price: $129.95 / £82.00

Catalog no. K14356, ISBN: 978-1-4398-9970-0 June 2012, 6-1/8 x 9-1/4, 272 pp. Suggested Price: $79.95 / £48.99 Also available as an eBook

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Drug Discovery and Development / Management

Transdermal and Intradermal Delivery of Therapeutic Agents

OMICs Technologies

63


Management / Pharmaceutical Science / Pharmacology 64

Patient-Focused Network Integration in BioPharma Strategic Imperatives for the Years Ahead Robert Handfield North Carolina State University, Raleigh, USA

The biopharmaceutical industry as we know it today is going through a massive change that is sending shudders to the huge populations who are facing healthcare uncertainty. This book argues that patient-focused network integration is the only way for organizational evolution to occur. It discusses how to align enterprises with the patient at the center. It details the historical context of the biopharmaceutical value chain, understand the current set of challenges facing the industry, and get a thorough presentation of the author’s unique and sustainable agenda for change. Catalog no. K15373, ISBN: 978-1-4665-5546-4 April 2013, 6-1/8 x 9-1/4, 264 pp. Suggested Price: $69.95 / £44.99 Also available as an eBook

Pharmaceutical Process Scale-Up Edited by

Quantitative Pharmacology An Introduction to Integrative Pharmacokinetic-Pharmacodynamic Analysis Johan Gabrielsson Swedish University of Agricultural Sciences, Uppsala, Sweden

Stephan Hjorth AstraZeneca R&D, Mölndal, Sweden

Pharmacokinetics (PK) and pharmacodynamics (PD) comprise traditionally distinct disciplines within pharmacology, the study of the interaction of drugs with the body. This book shows that by deliberately, intimately, and systematically integrating these disciplines our understanding of drugs and the efficiency and effectiveness of drug discovery and development may be greatly enhanced. The book is therefore written with a broad audience in mind and focuses on concepts. Pharmacologists of all sorts, safety scientists, pharmacokineticists, medicinal chemists, clinicians, statisticians, veterinarians, animal science professionals, project leaders, and students of medical, pharmaceutical and veterinary sciences are the primary targets. Catalog no. N10642, ISBN: 978-1-4665-6031-4 May 2012, 6-1/2 x 9-1/2, 264 pp. Suggested Price: $139.95 / £89.00

Scalable Green Chemistry Case Studies from the Pharmaceutical Industry Edited by

Michael Levin Metropolitan Computing Corporation, East Hanover, New Jersey Series: Drugs and the Pharmaceutical Sciences

The third edition of Pharmaceutical Process Scale-Up deals with the theory and practice of scale-up in the pharmaceutical industry. This thoroughly revised edition reflects the rapid changes in the field and includes material on tableting scale-up and compaction, regulatory appendices that cover FDA and EU guidelines, chapters on risk evaluation and validation as related to scale-up, and practical advice on scale-up solutions from world renowned experts in the field. Catalog no. H100123, ISBN: 978-1-61631-001-1 February 2011, 6 x 9, 530 pp. Suggested Price: $179.95 / £115.00

Stefan Koenig Sepracor Inc., Marlborough, Massachusetts, USA

Packed with real-world examples, this book illustrates the 12 principles of green chemistry. These diverse case studies demonstrate to scientists and students that beyond the theory, the challenges of green chemistry in pharmaceutical discovery and development remain an ongoing endeavor. By informing and welcoming additional practitioners to this mission, the negative environmental impact of pharmaceutical products will continue to be minimized. Green chemistry is the methodology by which chemical production in this industry can become more efficient, adding environmental stewardship to the noble mission of treating human disease. Catalog no. N10699, ISBN: 978-981-4316-49-1 January 2013, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Textbook

Basic Pharmacokinetics Disposable Bioprocessing Systems Sarfaraz K. Niazi

Second Edition Mohsen A. Hedaya Associate Professor, Department of Pharmaceutics, Kuwait University

Pharmaceutical Scientist Inc., Deerfield, Illinois, USA

Pharmacy Education Series

Written by a researcher with experience designing, establishing, and validating biological manufacturing facilities worldwide, this is the first comprehensive introduction to disposable systems for biological drug manufacturing. It reviews the current state of the industry; tackles questions about safety, costs, regulations, and waste disposal; and guides readers to choose disposable components that meet their needs. This practical manual covers disposable containers, mixing systems, bioreactors, connectors and transfers, controls and sensors, downstream processing systems, filling and finishing systems, and filters. The author also shares his predictions for the future, calling disposable bioprocessing technology a “game changer.”

Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. It is therefore vital to those engaged in the discovery, development, and preclinical and clinical evaluation of drugs, as well as practitioners involved in the clinical use of drugs. Accessible to a wide variety of readers, this volume demonstrates the quantitative pharmacokinetic relations and the interplay between pharmacokinetic parameters. Accompanying the book is a CD-ROM with self-instructional tutorials and pharmacokinetic and pharmacokinetic-pharmacodynamic simulations, allowing visualization of concepts for enhanced comprehension. This learning tool received an award from the American Association of Colleges of Pharmacy for innovation in teaching.

Catalog no. K12983, ISBN: 978-1-4398-6670-2 December 2011, 6-1/8 x 9-1/4, 322 pp. Suggested Price: $157.95 / £101.00

Figure slides are available upon qualifying course adoption

Also available as an eBook

Catalog no. K12311, ISBN: 978-1-4398-5073-2 February 2012, 6-1/8 x 9-1/4, 595 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

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Bioactive Compounds from Natural Sources Second Edition Natural Products as Lead Compounds in Drug Discovery Edited by

Current Research in Pharmaceutical Technology Edited by

Sabine Globig Hazard Community and Technical College, Kentucky, USA

William Hunter Jr.

Corrado Tringali Following the success of the first edition, this book continues to focus on the modern approach to the isolation of biologically active natural products and provides numerous examples of the isolation and characterization of secondary metabolites. The fully updated second edition places an emphasis on the synthetic or semi-synthetic analogues of natural products, relevant to those working on biomedical applications of natural products. The book is primarily addressed to researchers who are not necessarily chemists or pharmacologists. It includes chapters on general methods together with more specific chapters discussing the main topics in the field, including important families or properties of bioactive natural products, synthesis of analogues, biological evaluation of both natural and synthetic products, and structure-activity relationship studies. Catalog no. K11166, ISBN: 978-1-4398-2229-6 September 2011, 6-1/8 x 9-1/4, 648 pp. Suggested Price: $199.95 / £127.00

Pharmaceutical technology deals with the discovery, production, processing, and safe and effective delivery of medications to patients. Technologies involved include computer modeling for research, bioengineering for research instrumentation, processes, and methods for increasing production, and computing technology and biosystematics for the management and analysis of data. This new book covers a wide range of important topics on today’s pharmaceutical technology, such as in vitro drug release and controlled drug delivery, the use of nanotechnology in pharmaceuticals, quantum dot imaging, assessment, and efficacy of pharmaceuticals, and much more. Catalog no. N10600, ISBN: 978-1-926692-68-5 December 2011, 6-1/8 x 9-1/4, 274 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Also available as an eBook

Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds

Dermatokinetics of Therapeutic Agents Edited by

S. Narasimha Murthy

Edited by

The University of Mississippi, University, USA

Goutam Brahmachari

Presenting the first comprehensive reference on this important new area of research, this book provides an overview of the fundamentals of dermatokinetics: the study of drug uptake into skin layers. It offers a detailed discussion of dermatokinetics that is applicable to any route of administration and to different pharmaceutical drug delivery systems. The author includes a general overview of the theoretical as well as the practical aspects of dermatokinetics and addresses the impact of drug delivery system design on the dermatokinetics of drugs. Chapters cover such topics as dermatopharmacology, cutaneous microdialysis, and dermatokinetics of gene therapeutics.

Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, this volume presents cuttingedge research in the chemistry of bioactive natural products and helps the reader understand how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. The reference presents chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. It features chemical advances in naturally occurring organic compounds and describes their spectral properties, chemical transformations, and structure-activity relationships. Catalog no. K14122, ISBN: 978-1-4398-9167-4 February 2013, 7 x 10, 590 pp. Suggested Price: $149.95 / £95.00

Figure slides are available upon qualifying course adoption

Catalog no. K10264, ISBN: 978-1-4398-0477-3 April 2011, 6-1/8 x 9-1/4, 228 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

Also available as an eBook

Dictionary of Alkaloids Textbook

Chemistry of Natural Products A Laboratory Handbook N R Krishnaswamy Sri Sathya Sai Institute of Higher Learning, (retired), Anantapur, Andhra Pradesh, India

This book is a companion to Chemistry of Natural Products: A Unified Approach, Second Edition. It contains a judicious mix of both spectroscopic and chemical methods of characterisation of natural products. The main objective is to provide students with experimental details for the successful isolation of different types of natural products. All the experiments have been successfully class-tested. Catalog no. K14555, ISBN: 978-1-4665-0524-7 July 2012, 6-1/8 x 9-1/4, 216 pp. Suggested Price: $79.95 / £49.99

Pharmacology

Olean General Hospital, New York, USA

University of Catania, Italy

Second Edition with CD-ROM Edited by

John Buckingham, Keith H. Baggaley, Andrew D. Roberts, and László F. Szabó Drawn from the venerable Dictionary of Natural Products, this volume categorizes all known alkaloids to present their concise chemical, structural, and physical data. Doubled in size, this edition includes 20,000 entries with existing entries inspected and updated. Mirroring the book’s contents is an accompanying, searchable CD-ROM, allowing researchers to conduct high-speed electronic searches, or leisurely thumb through the book’s printed pages. With either format, readers will find access to data unparalleled in scope and depth. Catalog no. 77694, ISBN: 978-1-4200-7769-8 January 2010, 8-1/2 x 11, 2374 pp. Suggested Price: $893.00 / £568.00 Also available as an eBook

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65


Drug Delivery Systems Third Edition Vasant V. Ranade Director of Chemical Research, Academic Pharmaceuticals Inc, Lake Bluff, Illinois, USA

John B. Cannon

Edited by

Rensheng Xu, Yang Ye, and Weimin Zhao

Pharmacology

Targeted Drug Solutions, Grayslake, Illinois, USA

Shanghai Institute of Materia Medica, Pudong, China

The third edition of this popular book contains the latest research and development on drug delivery systems. It also contains a new chapter on nanoscience and technology for drug delivery along with cutting-edge business intelligence and strategies throughout the text. Like previous editions, it continues to provide readers with a multitude of possible drug delivery systems that can be used to improve therapeutics as well as information on the technology involved and the regulatory approaches that make them useful. The authors introduce complex drug delivery technology in an easy-to-understand format with numerous practical examples.

A collection of the most important research results of natural product chemistry in China, this reference covers basic principles of isolation, structure, characteristics, and the current research techniques of structure elucidation with wet chemistry and spectroscopic analysis. The book includes information on UV, IR, MS, and NMR, especially 2d-NMR, HMBC and HMQC, bioactivity, biosynthesis, and chemical synthesis. Written by experts in the field, topics are illustrated with examples from scientific experiments, making the book attractive to a broad audience, including graduate students and researchers.

An instructor’s manual and figure slides are available upon qualifying course adoption

Catalog no. K12793, ISBN: 978-1-4398-6076-2 July 2011, 7 x 10, 381 pp. Suggested Price: $93.95 / £59.99

Catalog no. K10307, ISBN: 978-1-4398-0618-0 April 2011, 6-1/8 x 9-1/4, 608 pp. Suggested Price: $209.95 / £134.00

Also available as an eBook

Also available as an eBook

Flavonoids and Related Compounds Bioavailability and Function

Marine Pharmacognosy

Edited by

Trends and Applications

Jeremy P. E. Spencer

Se-Kwon Kim

University of Reading, UK

Alan Crozier University of Glasgow, UK Series: Oxidative Stress and Disease

66

Introduction to Natural Products Chemistry

Flavonoids exert a multiplicity of biological effects on humans and can have beneficial implications for numerous disease states. This volume examines current knowledge regarding the absorption, metabolism, and bioavailability of individual flavonoids and related phenolic compounds. Edited by internationally recognized leaders in the field, the book presents contributions by a panel of experts who demonstrate the potential of flavonoids in ameliorating a range of disease states, including cardiovascular disease, Alzheimer’s and Parkinson’s disease and other neurodegenerative disorders, and cancer. This research provides a reliable starting point for further inquiry and experimentation. Catalog no. K12151, ISBN: 978-1-4398-4826-5 April 2012, 6-1/8 x 9-1/4, 471 pp. Suggested Price: $149.95 / £99.00 Also available as an eBook

Pukyong National University, Busan, South Korea

Marine pharmacognosy is a dynamic field that has been systematically investigated over the last 50 years. The potential of the field is shown by the number of publications and the patents that are constantly increasing every year. This book presents the latest comprehensive studies of marine-derived medicinal substances for biological, medical, and industrial applications. Marine flora and fauna has been the source of molecules used as pharmaceuticals, cosmeceuticals, nutraceuticals, molecular probes, fine chemicals, and agrochemicals. Bringing together a global author team of experts, this text provides a current snapshot of the importance of marine products in health formulation. Catalog no. K14137, ISBN: 978-1-4398-9229-9 December 2012, 7 x 10, 456 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

Pharmaceutical Formulation Development of Peptides and Proteins Second Edition

Ibuprofen

Edited by

A Critical Bibliographic Review, 2nd Edition

Novo Nordisk A/S, Malov, Denmark

Kim D. Rainsford Sheffield, Hallam University, Sheffield, UK

Already regarded as a standard reference for anyone who needs to know about the actions and uses of anti-inflammatory and analgesic drugs, this second edition provides even more. It updates information on the medicinal chemistry and the pharmaceutics of ibuprofen and its pharmacokinetics in both humans and animals. It includes molecular pharmacology and toxicological studies, and discusses the safety and efficacy of non-prescription ibuprofen, including its side effects. The text also addresses the therapeutic role of ibuprofen in rheumatic conditions, Alzheimer’s disease, and cancer. Catalog no. 46365, ISBN: 978-1-4200-4636-6 June 2013, 7 x 10, 896 pp. Suggested Price: $199.95 / £127.00 Also available as an eBook

Lars Hovgaard Sven Frokjaer and Marco van de Weert University of Copenhagen, Denmark

Rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential pose a challenge for pharmaceutical scientists who have to formulate these compounds as drug products. This book focuses on general pharmaceutical developmental aspects of peptides and proteins. The general principles of production, purification, degradation mechanisms, and analysis are discussed. Several chapters discuss the formulation design of peptides and proteins, including protein modification and alternative administration strategies. This second edition also includes chapters on the immunogenicity of protein pharmaceuticals and the biosimulation of pharmacokinetics and pharmacodynamics. Catalog no. K12494, ISBN: 978-1-4398-5388-7 November 2012, 6-1/8 x 9-1/4, 392 pp. Suggested Price: $159.95 / £99.00 Also available as an eBook

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Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Applications Fourth Edition

Current Pharmacy Review Hari R. Desu Ajit S. Narang

Swedish University of Agricultural Sciences, Uppsala

Bristol-Myers Squibb, Co., New Brunswick, New Jersey, USA

Daniel Weiner

Ram I. Mahato

West Virginia University, Morgantown, USA

University of Tennessee Health Science Center, Memphis, USA

This book raises the stature of PK/PD modeling to its highest level. This essential professional resource is regarded as the most comprehensive and practical guide to the design, analysis, and interpretation of kinetic and dynamic experiments. It provides the expertise needed to resolve commonly appearing problems with a pedagogic yet accessible approach. A staple in both undergraduate and graduate classrooms, this edition includes case studies to support basic concepts in PK/PD. This edition includes a CD with all exercises and WinNonlin model/ command files.

This book is a review for candidates preparing for the North American Pharmacist Licensure Examination (NAPLEX®). It includes review sections and review exercises on physical pharmacy, pharmaceutical dosage form and design, drug delivery, basic principles of medicinal chemistry, pharmacology and therapeutics, and pharmacy practice. Material is organized parallel to the pharmacy curriculum and presented in an outline format for easy use. Each chapter contains topic outlines and practice questions according to the pharmacy school curriculum. The format is intended to give the student an opportunity to review real cases accompanied by questions that address all of the NAPLEX® competency statements.

Catalog no. SP5100, ISBN: 978-9-19-765100-4 July 2007, 1250 pp. Suggested Price: $219.95 / £141.00

Catalog no. K15169, ISBN: 978-1-4665-5131-2 June 2013, 7 x 10, 704 pp., Soft Cover Suggested Price: $54.95 / £34.99 Also available as an eBook

Safety Pharmacology in Pharmaceutical Development Approval and Post Marketing Surveillance, Second Edition Shayne C. Gad Gad Consulting Services, Cary, North Carolina, USA

This book covers the regulatory required evaluation and study of the potentially adverse pharmacological effects of new drugs. Coverage ranges from the general regulatory requirements to the specific studies that must be done and how they are performed and interpreted. Based on more than 30 years of direct experience, the author describes tricks and practical insights for making studies work and understanding why they don’t. The second edition includes current regulations (US FDA and international—especially Europe and Japan) and updated test methods, interpretation, and science. Catalog no. K12039, ISBN: 978-1-4398-4567-7 April 2012, 6-1/8 x 9-1/4, 213 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Textbook

Textbook of Drug Design and Discovery Fourth Edition

Drug Delivery and Targeting For Pharmacists and Pharmaceutical Scientists Edited by

Anya M. Hillery, Andrew W. Lloyd, James Swarbrick An accessible and easy-to-read text, this is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications, and potential future developments, making it indispensable for pharmaceutical students, scientists and researchers. It covers how to optimize therapeutic efficacy; drug absorption, unwanted distribution and premature inactivation / elimination; attempts to minimize toxicity or alter immunogenicity; achieving rate-controlled drug release and effective drug targeting; routes of delivery; and technologies such as biosensors, microchips, stimuli-sensitive hydrogels, and plasmid-based gene therapy. Catalog no. TF1359, ISBN: 978-0-415-27198-1 September 2001, 7 x 10, 496 pp., Soft Cover Suggested Price: $104.95 / £66.99

Textbook

Essentials of Law and Ethics for Pharmacy Technicians Third Edition

Edited by

Povl Krogsgaard-Larsen, Ulf Madsen, and Kristian Strømgaard The Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark

Updated and revised, this fourth edition of a bestseller provides current and comprehensive information on all aspects of drug design and discovery. The first part of the book covers general aspects, methods, and principles and the second section covers specific targets and diseases. Topics new to this edition include biostructure- and ligand-based drug design, natural products, imaging, neurotransmitter transporters, opioid and cannabinoid receptors, hypnotics, neglected diseases, and antibiotics. Each chapter includes references for further study. Most chapters also supply background and history needed to provide context, as well as conclusions that summarize the important points.

Pharmacology / Pharmacy

Innopharma LLC, Piscataway, New Jersey, USA

Johan Gabrielsson

Kenneth M. Strandberg Fully revised to address the latest procedural, ethical, and technological developments in this rapidly changing field, this third edition of a bestseller includes a wealth of additional material, including an appendix on the legal standing of electronic transmission of prescriptions. It covers the latest in U.S. state and federal regulations pertaining to the administration of new medications, including birth control and the morningafter pill, as well as current regulations on over-the-counter label claims. An essential resource for students as well as practicing technicians, this reference brings together the information that pharmacy technicians need to practice in a manner that is both legal and ethical. An instructor’s manual and slides are available upon qualifying course adoption

Catalog no. 63227, ISBN: 978-1-4200-6322-6 October 2009, 7 x 10, 476 pp. Suggested Price: $91.95 / £58.99

Catalog no. K12451, ISBN: 978-1-4398-5315-3 July 2011, 6-1/8 x 9-1/4, 186 pp. Suggested Price: $55.95 / £35.99

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67


Pharmacy / Regulation, Standards, and Validation / Bioinformatics 68

Pharmaceutical Dosage Forms and Drug Delivery

Process Validation in Manufacturing of Biopharmaceuticals

Second Edition

Third Edition

Ram I. Mahato

Edited by

University of Tennessee Health Science Center, Memphis, USA

Anurag S. Rathore

Textbook

Ajit S. Narang

Indian Institute of Technology, New Delhi

Bristol-Myers Squibb, Co., New Brunswick, New Jersey, USA Series: Pharmacy Education

Designed to teach the basic principles of pharmaceutics, dosage form design, and drug delivery, this invaluable reference provides extensive revisions and updates to clarify concepts and include important principles and progress in the field. New chapters include: Pharmacy Math and Statistics, Compounding Principles and Practice, and Powders and Granules. It expands treatment of complexation and protein binding, discusses theoretical bases and mathematical treatment of drug release from different types of dosage forms, and includes the latest developments in biomaterials as well as protein and nucleic acid-based pharmaceutical dosage forms and therapeutics. Figure slides are available upon qualifying course adoption

Catalog no. K12224, ISBN: 978-1-4398-4918-7 October 2011, 6-1/8 x 9-1/4, 512 pp. Suggested Price: $119.95 / £80.00

Gail Sofer SofeWare Associates, Austin, Texas, USA Series: Biotechnology and Bioprocessing

Written by experienced authorities in process validation, this book explores strategies for selecting the most appropriate quality control processes. It offers practical guidelines, recommendations, and an abundance of industrial case studies that demonstrate various techniques and approaches in the validation of biopharmaceutical processes. This third edition of the text addresses the numerous changes made in the pharmaceutical industry as well as the many modifications that have been made to regulations. In addition, the authors also cover advances in biotechnology. Catalog no. K12321, ISBN: 978-1-4398-5093-0 May 2012, 6-1/8 x 9-1/4, 531 pp. Suggested Price: $169.95 / £108.00 Also available as an eBook

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Bayesian Phylogenetics

Textbook

Pharmacy What It Is and How It Works Third Edition William N. Kelly

Methods, Computational Algorithms, and Applications Edited by

Ming-Hui Chen, Lynn Kuo, and Paul O. Lewis University of Connecticut, Storrs, USA

William N. Kelly Consulting Inc., Oldsmar, Florida, USA

Series: Chapman & Hall/CRC Mathematical & Computational Biology

Series: Pharmacy Education

This book covers advances in Bayesian statistics as applied to the field of phylogenetics and coalescence-based population genetics. It is designed for statisticians who are interested in phylogenetic or population genetic applications, or biologists who are interested in the latest approaches to Bayesian modeling.

The health care and pharmacy environments have changed substantially since the second edition of this book. This updated reference includes new information, references, tables, charts, and figures. The book discusses how drugs are developed and used, and addresses concerns over medication errors. Discussion questions, exercises, and challenges are provided within the chapters to promote learning. A website accompanies the book upon purchase to provide additional reading. Figure slides are available upon qualifying course adoption

Catalog no. K12446, ISBN: 978-1-4398-5305-4 July 2011, 6-1/8 x 9-1/4, 488 pp. Suggested Price: $62.95 / £40.99 Also available as an eBook

Hazardous Drugs in Healthcare, Pharmaceutical and Veterinary Facilities Strategies in Achieving Compliance Samuel James Murff

Catalog no. K14380, ISBN: 978-1-4665-0079-2 June 2013, 6-1/8 x 9-1/4, 600 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Computational and Visualization Techniques for Structural Bioinformatics using Chimera Forbes J. Burkowski University of Waterloo, Ontario, Canada Series: Chapman & Hall/CRC Mathematical & Computational Biology

This book supplies comprehensive technical guidance to help readers establish and administer a model hazardous drugs program that limits or reduces employee and visitor exposure. It includes step-by-step instructions for establishing an air sampling and surface monitoring program that meets current regulatory guidelines (OSHA), consensus guidelines (NIOSH, ACGIH, American Society of Hospital Pharmacists), and new quality assurance requirements for pharmacies (JACHO). It also provides a complete safety and health overview of other hazardous drugs that are not considered to be cytotoxic or antineoplastic drugs.

This book emphasizes computer programs that analyze protein structural data with program output generating data files and visual feedback in the form of a molecular display. The theoretical part of the text considers both the mathematical models related to molecular structure and the computational strategies that work with these models to derive results. The practical part of the text presents UCSF Chimera as a “workbench” that provides a Python programming environment and the ability to see program output in the molecular display. The accompanying CD-ROM includes Python code, color figures, and session files for Chimera.

Catalog no. K15435, ISBN: 978-1-4665-5676-8 June 2013, 7 x 10, 800 pp. Suggested Price: $189.95 / £121.00

Catalog no. K11654, ISBN: 978-1-4398-3661-3 June 2013, 6-1/8 x 9-1/4, 256 pp. Suggested Price: $79.95 / £49.99

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Computational Systems Biology of Cancer Emmanuel Barillot, Laurence Calzone, Philippe Hupe, Jean-Philippe Vert, and Andrei Zinovyev

Introduction to Bio-Ontologies

Institut Curie, Paris, France

Charite Universitatsmedizin Berlin, Germany

Series: Chapman & Hall/CRC Mathematical & Computational Biology

Series: Chapman & Hall/CRC Mathematical & Computational Biology

Drawn from the authors’ decade-long work in the cancer computational systems biology laboratory at Institut Curie, this self-contained guide explains how to apply computational systems biology approaches to cancer research. Suitable for readers in both computational and life sciences, the book provides proven techniques and tools for cancer bioinformatics and systems biology research. It explores how computational systems biology can help fight cancer in three essential aspects: categorizing tumors, finding new targets, and designing improved and tailored therapeutic strategies.

Exploring the computational background of ontologies, this self-contained text helps readers understand ontological algorithms and their applications. It describes a host of bio-ontologies, including gene ontology and human phenotype ontology. The authors cover graph and inference algorithms and explain how these algorithms are used in biological and biomedical applications. They also offer overviews of the R programming language and the W3C standards of XML, RDF, and OWL. Along with extensive references and many exercises, the book provides software and data on a supporting website.

Catalog no. K11531, ISBN: 978-1-4398-3144-1 August 2012, 6-1/8 x 9-1/4, 461 pp. Suggested Price: $79.95 / £49.99

Catalog no. K11656, ISBN: 978-1-4398-3665-1 June 2011, 6-1/8 x 9-1/4, 517 pp. Suggested Price: $79.95 / £49.99 Also available as an eBook

An Introduction to Statistics and Data Analysis for Bioinformatics using R

Data Mining for Bioinformatics Sumeet Dua and Pradeep Chowriappa Louisiana Tech University, Ruston, USA

Data Mining for Bioinformatics enables researchers to meet the challenge of mining vast amounts of biomolecular data to discover real knowledge. Covering theory, algorithms, and methodologies, as well as data mining technologies, it presents a thorough discussion of data-intensive computations used in data mining applied to bioinformatics. The book explains data mining design concepts to build applications and systems. Showing how to prepare raw data for the mining process, the text is filled with heuristics that speed the data mining process. Catalog no. 2801, ISBN: 978-0-8493-2801-5 October 2012, 6-1/8 x 9-1/4, 350 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Sorin Draghici Wayne State University, Detroit, Michigan, USA Series: Chapman & Hall/CRC Mathematical & Computational Biology

From the very basics to linear models, this book provides a complete introduction to statistics, data analysis, and R for bioinformatics research and applications. It covers linear models, ANOVA, cluster analysis, visualization tools, and machine learning techniques. Suitable for self-study and courses in computational biology, bioinformatics, statistics, and the life sciences, the text also presents examples of microarrays and bioinformatics applications. R code illustrates all of the essential concepts and is available on an accompanying CD-ROM. Catalog no. K14140, ISBN: 978-1-4398-9236-7 March 2013, 6-1/8 x 9-1/4, 506 pp. Suggested Price: $79.95 / £49.99 Also available as an eBook

Multiobjective Optimization Methodology

Genome Annotation

A Jumping Gene Approach

Jung Soh, Paul M.K. Gordon, and Christoph W. Sensen

K.S. Tang, T.M. Chan, R.J. Yin, and K.F. Man

University of Calgary, Alberta, Canada

City University of Hong Kong, China

Series: Chapman & Hall/CRC Mathematical & Computational Biology

Series: Industrial Electronics

This thorough overview explores automated genome analysis and annotation from its origins to the challenges of next-generation sequencing data analysis. It explains how current analysis strategies were developed, including sequencing strategies, statistical models, and early annotation systems. The authors then present visualization techniques for displaying integrated results as well as stateof-the-art annotation tools, including MAGPIE, Ensembl, Bluejay, and Galaxy. They also discuss the pipelines for the analysis and annotation of complex, next-generation DNA sequencing data. MAGPIE and Bluejay are available on a CD-ROM.

Deriving engineering designs from multiobjective optimization techniques is a challenging task, particularly when design criteria conflict performance requirements. The first book to focus on jumping genes outside bioscience and medicine, Multiobjective Optimization Methodology: A Jumping Gene Approach introduces jumping gene algorithms designed to supply viable, adequate solutions to multiobjective problems quickly and with low computational cost. Reviewing state-of-the-art multiobjective optimization techniques, it covers the fundamental concept, theoretical justification, simulation verifications, and applications of the jumping gene in evolutionary computation. The book provides the technical know-how to obtain crucial tradeoff solutions between convergence and diversity.

Catalog no. K11912, ISBN: 978-1-4398-4117-4 August 2012, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Bioinformatics

Peter N. Robinson and Sebastian Bauer

Catalog no. K14344, ISBN: 978-1-4398-9919-9 May 2012, 6-1/8 x 9-1/4, 279 pp. Suggested Price: $139.95 / £89.00 Also available as an eBook

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69


Textbook

Quantitative Biology Edited by

Adaptive Motion Compensation in Radiotherapy

Michael E. Wall

Edited by

Los Alamos National Laboratory, New Mexico, USA

Martin J. Murphy

From Molecular to Cellular Systems

Bioinformatics / Biostatistics

Series: Chapman & Hall/CRC Mathematical & Computational Biology

Virginia Commonwealth University, Richmond, USA

Providing an overview of quantitative biology, this book presents practical tools for the observation, modeling, design, and manipulation of biological systems from the molecular to cellular levels. The chapters offer an introduction to fundamental concepts and computational, mathematical, and experimental studies of molecular and cellular behavior. The first section of the text covers basic, integrative concepts that form the foundation of the field. The next section reviews state-of-the-art methods in quantitative biology and case studies of specific systems. The last section focuses on important biological systems where modern quantitative methods are making an impact.

Reflecting recent advances in the field, this book provides the first detailed treatment of online interventional techniques for motion compensation radiotherapy. It explains how adaptive motion intervention is imaging-intensive and relies on near real-time image acquisition and processing. With a focus on the strategy of online motion compensation, the book discusses necessary motion detection methodology, repositioning methodology, and how to interpret and respond to target movement data in real time. It covers methods of detection and correction and then offers examples. It also gives attention to the distinct problems in dose planning and delivery posed by each adaptation technology.

Figure slides are available upon qualifying course adoption

Catalog no. K11160, ISBN: 978-1-4398-2193-0 December 2011, 8-1/2 x 11, 165 pp. Suggested Price: $157.95 / £101.00

Catalog no. K11344, ISBN: 978-1-4398-2722-2 August 2012, 7 x 10, 392 pp. Suggested Price: $89.95 / £57.99

Textbook

Statistics and Data Analysis for Microarrays Using R and Bioconductor

Advanced Bayesian Methods for Medical Test Accuracy

Second Edition

Lyle D. Broemeling

Sorin Drˇaghici Wayne State University, Detroit, Michigan, USA Series: Chapman & Hall/CRC Mathematical & Computational Biology

70

Also available as an eBook

Also available as an eBook

Richly illustrated in color, this bestselling text provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that explains the basics of R and microarray technology as well as how to choose and apply the proper data analysis tool to specific problems. Now using R and Bioconductor, this edition has been expanded with 14 new chapters and 600 more pages. R code is available on a CD-ROM. Figure slides are available upon qualifying course adoption

Broemeling and Associates, Medical Lake, Washington, USA Chapman & Hall/CRC Biostatistics Series

After a review of the usual measures, including specificity, sensitivity, positive predictive value, negative predictive value, and the area under the ROC curve, this book expands its scope to cover the more advanced topics of verification bias, diagnostic tests with imperfect gold standards, and medical tests where no gold standard is available. The author offers a practical treatment by including R and WinBUGS code in the examples and by employing the Bayesian approach throughout the text. He also provides practical problems at the end of each chapter. Catalog no. K11763, ISBN: 978-1-4398-3878-5 August 2011, 6-1/8 x 9-1/4, 487 pp. Suggested Price: $146.95 / £94.00

Catalog no. K10487, ISBN: 978-1-4398-0975-4 December 2011, 6-1/8 x 9-1/4, 1036 pp. Suggested Price: $89.95 / £57.99

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Age-Period-Cohort Analysis

Textbook

New Models, Methods, and Empirical Applications

Stochastic Modelling for Systems Biology Second Edition Darren J. Wilkinson

Yang Yang University of North Carolina, Chapel Hill, USA

Kenneth C. Land Duke University, Durham, North Carolina, USA

School of Mathematics and Statistics, Newcastle University, UK

Series: Chapman & Hall/CRC Interdisciplinary Statistics

Series: Chapman & Hall/CRC Mathematical & Computational Biology

The social sciences, demography, and epidemiology have faced a long-standing problem of analysis of data in which events or outcome variables can be simultaneously affected by time periods (P) in which they occur as well as by the ages (A) and birth cohorts (C) or dates of origin of individuals or other units to which they occur. This book uses the GLMM approach to bring APC analysis to the twenty-first century of statistical practice. Written to accommodate readers less sophisticated in statistical modeling, this book presents a variety of empirical applications and interdisciplinary topics.

This book provides an accessible introduction to the use of stochastic processes for modeling biological systems, such as genetic and biochemical networks. Focusing on simulation, the text includes many examples, R and SBML code, and a number of computer-based exercises. Fully updated, this second edition includes improvements to the chapters on Markov processes, kinetics, and approximate algorithms. It also greatly expands the coverage of statistical inference, using likelihood-free techniques. Updated computing aspects include a new R package and the use of the new SBML Level 3. Figure slides are available upon qualifying course adoption

Catalog no. K11715, ISBN: 978-1-4398-3772-6 November 2011, 6-1/8 x 9-1/4, 363 pp. Suggested Price: $93.95 / £59.99

Catalog no. K14675, ISBN: 978-1-4665-0752-4 February 2013, 6-1/8 x 9-1/4, 280 pp. Suggested Price: $79.95 / £49.99 Also available as an eBook

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Analysis of Questionnaire Data with R Bruno Falissard

Applied Survey Data Analysis Steven G. Heeringa, Brady T. West, and Patricia A. Berglund University of Michigan, Ann Arbor, USA

Addressing the problem of analysis of questionnaire data and interpretation of results, this book proposes a methodology that uses R software. The author takes a practical approach to the subject, presenting principles first followed by detailed examples of their application to real data. He discusses principles of data management and manipulation, and covers descriptive statistics, statistical modeling, reliability, and missing data. The book focuses on R packages that are readily available and integrates discussion of their implementation and code throughout. All the data sets and R code packages are provided on a website. Catalog no. K10917, ISBN: 978-1-4398-1766-7 September 2011, 6-1/8 x 9-1/4, 280 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

With many examples and exercises based on major real-world survey data sets, this book provides a practical statistical overview of the analysis of complex sample survey data. It presents many methods and models for survey data analysis, including the linear regression, generalized linear, Cox proportional hazards, and discrete time models. It also explores new developments in advanced statistical techniques, such as multilevel analysis of survey data. The authors show how design characteristics are easily incorporated into the statistical methods and software for survey estimation and inference. Although Stata is used for most examples in the text, other software code is also offered on the book’s website. Catalog no. C8066, ISBN: 978-1-4200-8066-7 April 2010, 6-1/8 x 9-1/4, 487 pp. Suggested Price: $83.95 / £52.99 Also available as an eBook

Textbook

Applied Medical Image Processing

Artificial Human Sensors

A Basic Course

Science and Applications

Wolfgang Birkfellner

Edited by

Associate Professor, Department of Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria

Peter Wide

Using real medical images and techniques, this book provides a truly introductory guide to medical image processing. The author combines clearly written explanations with numerous tables, diagrams, and figures as well as illustrative examples and exercises using MATLAB® and Octave. An accompanying CD contains images and files to be used with either program. Topics discussed include image representation, operations in intensity space, segmentation methods, filtering and transformation, Fourier signal representation, spatial transforms, visualization techniques, image fusion, and tomographic volume reconstruction.

As the elderly population increases, the importance of creating sophisticated information support to humans with limited sensing performance has also grown. This book discusses human and artificial sensing in conjunction with human perception capabilities (auditory, taste, smell, vision, and touch). It also discusses the fusion of this sensing information to find answers to questions such as how we can increase our human “fuzzy” decision capability (perception). The book presents intelligent new technologies that can enhance the natural sensing, perception, and mobility abilities of humans, allowing them to have healthier, more productive, safer lives.

Catalog no. K11176, ISBN: 978-1-4398-2444-3 September 2010, 6-1/8 x 9-1/4, 403 pp. Suggested Price: $76.95 / £48.99

Catalog no. N10431, ISBN: 978-981-4241-58-8 March 2012, 6 x 9, 220 pp. Suggested Price: $149.95 / £95.00

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Orebro University, Sweden

Applied Medical Statistics Using SAS Geoff Der University of Glasgow, Scotland, UK

The A-Z of Error-Free Research

Brian S. Everitt

Biostatistics

Series: Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences

INSERM U669, Paris, France

Professor Emeritus, Institute of Psychiatry, King’s College, London

Phillip I. Good

Designed for medical statisticians, this intermediate-level reference explores the use of SAS for analyzing medical data. A chapter on visualizing data includes a detailed account of graphics for investigating data and smoothing techniques. The book also includes chapters on measurement in medicine, epidemiology/ observational studies, meta-analysis, Bayesian methods, and handling missing data. The book maintains an example-based approach, with SAS code and output included throughout and available online.

This practical book begins with an overview of when—and when not—to use statistics. It guides readers through the planning and data collection phases and presents various data analysis techniques, including methods for sample size determination. The author then covers techniques for developing models that provide a basis for future research. He also discusses reporting techniques to ensure research efforts get the proper credit. The book concludes with casecontrol and cohort studies. R code is included to implement the methods.

Catalog no. K13087, ISBN: 978-1-4398-6797-6 October 2012, 6-1/8 x 9-1/4, 559 pp. Suggested Price: $89.95 / £57.99

Catalog no. K14287, ISBN: 978-1-4398-9737-9 August 2012, 5-1/2 x 8-1/2, 269 pp., Soft Cover Suggested Price: $49.95 / £31.99

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Consultant, Huntington Beach, California, USA

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71


Bayesian Adaptive Methods for Clinical Trials Scott M. Berry Berry Consultants, College Station, Texas, USA

Bradley P. Carlin University of Minnesota, Minneapolis, USA

J. Jack Lee and Peter Müller The University of Texas M.D. Anderson Cancer Center, Houston, USA Chapman & Hall/CRC Biostatistics Series

Biostatistics

Written by leading pioneers of Bayesian clinical trial designs, this book explores the growing role of Bayesian thinking in clinical trial analysis. Covering Phase I, II, and III clinical trials, it establishes the basic principles before extending them to specific phases and endpoints. The authors also discuss special topics that span different phases of the process, including the use of historical data, equivalence studies, multiplicity and multiple comparisons, and subgroup analysis. They provide many detailed examples drawing on real data sets. Along with other materials, the R and WinBUGS codes used throughout are available on supporting websites. Catalog no. K11217, ISBN: 978-1-4398-2548-8 July 2010, 6-1/8 x 9-1/4, 323 pp. Suggested Price: $99.95 / £62.99 Also available as an eBook

Bayesian Analysis Made Simple An Excel GUI for WinBUGS Phil Woodward

72

Bayesian Methods in Health Economics Gianluca Baio Department of Statistical Science, University College London, UK Chapman & Hall/CRC Biostatistics Series

Health economics is concerned with the study of the cost-effectiveness of health care interventions. This book provides an overview of Bayesian methods for the analysis of health economic data. After an introduction to the basic economic concepts and methods of evaluation, it presents Bayesian statistics using minimal mathematics. The next chapters describe cost-effectiveness analysis from a statistical viewpoint, and Bayesian computation, notably MCMC. The final chapter presents three detailed case studies covering cost-effectiveness analyses using individual data from clinical trials, evidence synthesis and hierarchical models and Markov models. The text uses WinBUGS and JAGS, with datasets and code available online. Catalog no. K14236, ISBN: 978-1-4398-9555-9 November 2012, 6-1/8 x 9-1/4, 243 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Benefit Risk Analysis in Pharmaceutical Research and Development Edited by

Pfizer, LTD, Sandwich, Kent, UK

Andreas Sashegyi, James Felli, and Rebecca Noel

Chapman & Hall/CRC Biostatistics Series

Eli Lilly and Company, Indianapolis, Indiana, USA

From simple NLMs to complex GLMMs and beyond, this book describes how to use the GUI for WinBUGS—BugsXLA—an Excel add-in written by the author that allows a range of Bayesian models to be easily specified. With case studies throughout, the text shows how to routinely apply even the more complex aspects of model specification, such as GLMMs, outlier robust models, random effects Emax models, auto-regressive errors, and Bayesian variable selection. It provides brief, up-to-date discussions of current issues in the practical application of Bayesian methods. The author also explains how to obtain free software to get started immediately.

This work presents an overview of benefit-risk assessment approaches for pharmaceutical research and development. It covers various decision-making points along the R&D spectrum that would benefit from benefit risk analysis, including during lead development and optimization, early and late planning of clinical development, and regulatory review. The book also looks at health outcomes and comparative effectiveness analysis. In addition, the authors address current and future barriers to using risk-benefit modeling, including greater regulatory acceptance.

Catalog no. K11808, ISBN: 978-1-4398-3954-6 August 2011, 6-1/8 x 9-1/4, 364 pp. Suggested Price: $72.95 / £46.99

Catalog no. K13085, ISBN: 978-1-4398-6794-5 May 2013, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $89.95 / £57.99

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Bayesian Disease Mapping

Textbook

Hierarchical Modeling in Spatial Epidemiology, Second Edition Andrew B. Lawson Medical University of South Carolina, Charleston, USA

Chapman & Hall/CRC Biostatistics Series

Biostatistics A Computing Approach Stewart Anderson University of Pittsburgh, Pennsylvania, USA

Series: Chapman & Hall/CRC Interdisciplinary Statistics, 32

Chapman & Hall/CRC Biostatistics Series

This work provides an overview of the main areas of Bayesian hierarchical modeling and its application to the geographical analysis of disease. It explores a range of topics in Bayesian inference and modeling, including Markov chain Monte Carlo methods, Gibbs sampling, the Metropolis–Hastings algorithm, goodness-of-fit measures, and residual diagnostics. The new edition includes new chapters on putative health hazard modeling and spatial and spatiotemporal surveillance, as well as many other changes and additions. Notably, the computing has been updated to reflect advances in software. The book also includes new datasets and examples.

Focusing on visualization and computational approaches with an emphasis on the importance of simulation, this book introduces modern and classical biostatistical methods and compares their respective usefulness. It covers essential topics in biostatistical science, including simple linear regression, multivariate regression, repeated measure, nonparametric analysis, survival analysis, sample size, and power calculations. Assuming only basic knowledge of probability and statistics, the text offers numerous practical applications and detailed worked examples taken from the medical area, all computed using R and SAS, as well as exercises with solutions.

Catalog no. K14543, ISBN: 978-1-4665-0481-3 February 2013, 6-1/8 x 9-1/4, 392 pp. Suggested Price: $89.95 / £57.99

Catalog no. C8342, ISBN: 978-1-58488-834-5 December 2011, 6-1/8 x 9-1/4, 326 pp. Suggested Price: $83.95 / £41.99 Also available as an eBook

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Coherent Raman Scattering Microscopy Causal Inference

Edited by

Miguel A. Hernan

Purdue University, West Lafayette, Indiana, USA

Harvard School of Public Health, Boston, Massachusetts, USA

Xiaoliang Sunney Xie

James M. Robins

Harvard University, Cambridge, Massachusetts, USA

Harvard School of Public Health, Boston, Massachusetts, USA

Series in Cellular and Clinical Imaging

The application of causal inference methods is growing exponentially in fields that deal with observational data. Written by pioneers in the field, this practical book presents an authoritative yet accessible overview of the methods and applications of causal inference. With a wide range of detailed, worked examples using real epidemiologic data as well as software for replicating the analyses, the text provides a thorough introduction to the basics of the theory for non-timevarying treatments and the generalization to complex longitudinal data.

Edited by pioneers in the field and with contributions from a distinguished team of experts, this color book explains how CRS can be used to obtain a pointby-point chemical map of live cells and tissues. It discusses the principles of nonlinear optical spectroscopy and presents the theories of contrast mechanisms pertinent to CRS microscopy. The text then provides important technical aspects of CRS microscopy, including microscope construction, detection schemes, and data analyses. It also covers applications that demonstrate how CRS microscopy has become a valuable tool in biomedicine.

Catalog no. C7616, ISBN: 978-1-4200-7616-5 June 2013, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $49.95 / £31.99 Also available as an eBook

Clinical Trial Data Analysis Using R

Catalog no. K13060, ISBN: 978-1-4398-6765-5 November 2012, 7 x 10, 610 pp. Suggested Price: $149.95 / £95.00

University of Rochester Medical Center, New York, USA

Dose Finding by the Continual Reassessment Method

Karl E. Peace

Ying Kuen Cheung

Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, USA

Department of Biostatistics, Columbia University, New York, New York, USA

Ding-Geng (Din) Chen

Chapman & Hall/CRC Biostatistics Series

Chapman & Hall/CRC Biostatistics Series

This book thoroughly covers biostatistical analyses of clinical trial data and shows step by step how to implement the statistical methods using R. Each chapter presents examples of clinical trials based on the authors’ actual experiences in clinical drug development. Various biostatistical methods for analyzing the data are then identified. The authors also develop analysis code using appropriate R packages and functions. This approach enables readers to gain an understanding of the analysis methods and R implementation so that they can use R to analyze their own clinical trial data.

This book presents the continual reassessment method (CRM) as a tool for dosefinding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM may be calibrated and extended to suit common clinical settings. The book includes examples of real clinical trials data to illustrate the calibration techniques and shows how R can be used to carry out the techniques. It reviews the literature, related methodology, and theoretical properties of the CRM. It also explores alternatives for situations where the CRM fails.

Catalog no. K11861, ISBN: 978-1-4398-4020-7 December 2010, 6-1/8 x 9-1/4, 387 pp. Suggested Price: $93.95 / £59.99

Catalog no. C9151, ISBN: 978-1-4200-9151-9 March 2011, 6-1/8 x 9-1/4, 200 pp. Suggested Price: $83.95 / £52.99

Also available as an eBook

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Cluster Randomised Trials London School of Hygiene & Tropical Medicine, UK

Dynamic Prediction in Clinical Survival Analysis

Lawrence H. Moulton

Hans van Houwelingen and Hein Putter

Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

Leiden University, The Netherlands

Richard J. Hayes

Series: Chapman & Hall/CRC Interdisciplinary Statistics

Exploring the design, conduct, and analysis of CRTs, this book presents simple methods that are easy to apply with readily available statistical software and that perform well under the conditions experienced in most CRTs. It provides substantial material on study design options and includes a variety of practical examples from both developing and industrialized countries, with many of the examples based on the authors’ own research. The book also illustrates the application of analytical methods through several data sets from actual trials and shows how data can be analyzed using Stata. The data sets are available for download online. Catalog no. C8164, ISBN: 978-1-58488-816-1 January 2009, 6-1/8 x 9-1/4, 338 pp. Suggested Price: $97.95 / £59.99

Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability

In the last 20 years, dynamic prediction models have been extensively used to monitor patient prognosis in survival analysis. Written by one of the pioneers in the area, this book synthesizes these developments in a unified framework. It covers a range of models, including prognostic and dynamic prediction of survival using genomic data and time-dependent information. The text includes numerous examples using real data taken from the authors’ collaborative research. R programs are provided for implementing the methods. Catalog no. K11593, ISBN: 978-1-4398-3533-3 November 2011, 7 x 10, 250 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

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Biostatistics

Ji-Xin Cheng

73


Emerging Imaging Technologies in Medicine Edited by

Mark A. Anastasio Washington University, St. Louis, Missouri, USA

Patrick La Riviere

Event History Analysis with R Göran Broström Professor emeritus of statistics, Centre for Population Studies, Umeå University

Biostatistics

University of Chicago, Illinois, USA

Chapman & Hall/CRC The R Series

This book offers a comprehensive survey of emerging medical imaging technologies that show great promise for routine clinical use. Each chapter provides a detailed discussion of the physics/technology and addresses improvements in terms of dose, sensitivity, and/or specificity, which are limitations of current imaging approaches. The book reflects the major advances in computer hardware, nanofabrication, and laser technology that have led to developments in phase-contrast imaging, photoacoustic imaging, and optical imaging. It covers multimodality imaging, including PET/MRI, as well as threedimensional microscopy.

With an emphasis on social science applications, this book presents an introduction to survival and event history analysis. It focuses on practical applications in the fields of demography, epidemiology, and econometrics. The text includes a wide range of real examples, with data available online and supported by a dedicated R package for performing all of the analyses. Keeping mathematical details to a minimum, the author covers key topics, including both discrete and continuous time data, parametric proportional hazards, and accelerated failure times. He also describes how to use methods that are not available in other software for survival analysis.

Catalog no. K13780, ISBN: 978-1-4398-8041-8 December 2012, 8-1/2 x 11, 363 pp. Suggested Price: $169.95 / £108.00

Catalog no. K11534, ISBN: 978-1-4398-3164-9 April 2012, 6-1/8 x 9-1/4, 236 pp. Suggested Price: $79.95 / £49.99

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Textbook

Epidemiology Study Design and Data Analysis, Second Edition Mark Woodward Mount Sinai Medical Center, New York, New York, USA

74

Flexible Parametric Survival Analysis Using Stata Beyond the Cox Model Patrick Royston

Chapman & Hall/CRC Texts in Statistical Science

University College London and MRC Clinical Trials Unit, UK

Discussing techniques used in report writing, models for diagnostics, and design issues, this book covers the spectrum of statistical principles and analytical tools used in epidemiological research. This second edition includes new material on systematic evaluation, meta-analysis, regression dilution, case-cohort studies, case-crossover studies, pooled logistic regression and a companion website containing data sets for examples and exercises, SAS and Stata code for examples, a sample size calculator, and a SAS floating absolute risk macro. The author favors the use of basic mathematics and practical methods over complicated mathematical proofs, making the book comprehensive yet accessible.

Through real-world case studies, this book shows how to use Stata to estimate a class of flexible parametric survival models. It discusses the modeling of timedependent and continuous covariates and looks at how relative survival can be used to measure mortality associated with a particular disease when the cause of death has not been recorded. The book describes simple quantification of differences between any two covariate patterns through calculation of timedependent hazard ratios, hazard differences, and survival differences.

Catalog no. C415X, ISBN: 978-1-58488-415-6 November 2004, 6-1/8 x 9-1/4, 872 pp. Suggested Price: $109.95 / £52.99

Catalog no. N10372, ISBN: 978-1-59718-079-5 August 2011, 6 x 9, 339 pp., Soft Cover Suggested Price: $79.95 / £49.99

Essentials of Functional MRI

Handbook of SAS® DATA Step Programming

Patrick W. Stroman

Paul C. Lambert University of Leicester, UK

Queen’s University, Kingston, Ontario, Canada

Arthur Li

Functional magnetic resonance imaging (fMRI) is widely recognized as one of the most powerful tools available for basic and clinical research. With a minimum of technical jargon and advanced mathematics, this book presents a solid, practical foundation for readers to become conversant with fMRI as a tool for their own research and practice. The author reviews research and clinical applications for disease diagnosis, treatment monitoring, and surgical planning. He also covers the underlying biophysical mechanisms that relate MRI changes to neuronal activity as well as the expanded use of fMRI beyond the brain to the brainstem and spinal cord.

Preparing a dataset for analysis is perhaps the most important part of the entire data analysis process. Although there are many books on SAS programming, they often completely overlook, or have very brief coverage of, data manipulation and cleaning. This book, aimed at novice users, gives a broad introduction to data step programming in SAS. It focuses on understanding how the processes work, with detailed descriptions of the syntax. It includes lots of examples to help illustrate the methods and to help the reader gain a better understanding of how to prepare their data for analysis in SAS. The text also provides exercises and offers a supplementary website with code, data, solutions, and PowerPoint slides.

Catalog no. K10992, ISBN: 978-1-4398-1878-7 June 2011, 7 x 10, 311 pp., Soft Cover Suggested Price: $83.95 / £52.99

Catalog no. K15213, ISBN: 978-1-4665-5238-8 March 2013, 6-1/8 x 9-1/4, 224 pp. Suggested Price: $59.95 / £38.99

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Human Eye Imaging and Modeling A Handbook of Statistical Analyses using SAS

Edited by

E. Y. K. Ng Nanyang Technological University, Singapore

Third Edition

Jen Hong Tan

Geoff Der

U. Rajendra Acharya

Ngee Ann Polytechnic, Clementi, Singapore

University of Glasgow, Scotland, UK

Ngee Ann Polytechnic, Singapore

Brian S. Everitt

Jasjit S. Suri

King’s College, University of London, UK

Advanced image processing and mathematical modeling techniques are increasingly being used for the early diagnosis of eye diseases. This comprehensive reference details the latest advances and computer-based techniques in imaging and modeling of the human eye. Featuring contributions by well-known experts in the field, it covers imaging of fundus and infrared images, diagnosis of diabetes retinopathy and glaucoma, estimation of tear evaporation of dry eye, computer simulation of the human eye based on principles of heat transfer, various bioheat equations to predict interior temperatures based on the surface temperatures, and more.

Catalog no. C7842, ISBN: 978-1-58488-784-3 December 2008, 6-1/8 x 9-1/4, 392 pp., Soft Cover Suggested Price: $65.95 / £41.99

Catalog no. K13217, ISBN: 978-1-4398-6993-2 June 2012, 6-1/8 x 9-1/4, 430 pp. Suggested Price: $189.95 / £121.00

Biostatistics

Global Biomedical Technologies, Inc., California, USA

Remaining the go-to resource for learning how to use SAS for many kinds of statistical analysis, this third edition of a bestseller explains how to conduct a range of statistical analyses using the latest version of SAS. It illustrates each type of analysis with numerous real-world data examples, such as environmental causes of diseases, hypertension treatment, and gastric cancer treatment. This edition presents the new graphics procedures of SAS 9.2. It also includes more end-of-chapter exercises and selected answers in the appendix, along with a solutions manual that provides SAS code, output, and comments. The SAS programs and data sets used in the book are available online.

A Handbook of Statistical Analyses Using Stata Fourth Edition

Image Analysis and Modeling in Opthalmology

Brian S. Everitt King’s College, University of London, UK

Edited by

Sophia Rabe-Hesketh University of California, Berkeley, USA

E. Y. K. Ng, U. Rajendra Acharya, Jasjit S. Suri, and Aurelio Campilho

Fully updated, the fourth edition of this highly acclaimed and perpetually bestselling text demonstrates how a wide variety of statistical analyses, including descriptive statistics, graphics, and model estimation and diagnostics, can be performed using Stata version 9. The authors present many of Stata’s novel features, including a new mixed-models estimation command and a new matrix language. This edition also contains additional exercises that use various data sets and numerous examples of real-life data, enabling a better understanding of the methodology. The book offers selected solutions in an appendix as well as a solutions manual with qualifying course adoptions.

Successful thermal modeling of the human eye helps in the early diagnosis of eye abnormalities such as inflammation, cataracts, diabetic retinopathy, and glaucoma—all leading causes of blindness. This book presents a unified work of eye imaging and modeling techniques that have been proposed and applied to ophthalmologic problems. It delves into various morphological, texture, higher order spectra, and wavelet transformation techniques used to extract important diagnostic features from images, which can then be analyzed by a data scientist for automated diagnosis.

Catalog no. C7567, ISBN: 978-1-58488-756-0 November 2006, 6 x 9, 352 pp., Soft Cover Suggested Price: $72.95 / £46.99

Catalog no. K15531, ISBN: 978-1-4665-5930-1 May 2013, 7 x 10, 500 pp. Suggested Price: $199.95 / £127.00

Handbook of Statistics in Clinical Oncology

Also available as an eBook

Third Edition

Informatics in Medical Imaging

Edited by

John Crowley Chief Executive Officer, Cancer Research and Biostatistics, Seattle, Washington, USA

Edited by

George C. Kagadis University of Patras, Rion, Greece

Antje Hoering Senior Biostatistician, Cancer Research and Biostatistics Affiliate Assistant Professor, Department of Biostatistics, University of Washington Affiliate Investigator, Fred Hutchinson Cancer Research Center, Seattle, Washington

Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials. Accessible to statisticians in clinical trials as well as oncologists interested in clinical trial methodology, the book presents upto-date statistical approaches to the design and analysis of oncology clinical trials. New topics in this edition include trial designs for targeted agents, Bayesian trial design, and the inclusion of high-dimensional data and imaging techniques. This edition also contains numerous figures and examples to better explain concepts. Catalog no. K12872, ISBN: 978-1-4398-6200-1 March 2012, 6-1/8 x 9-1/4, 657 pp. Suggested Price: $119.95 / £76.99

Steve G. Langer Mayo Clinic, Rochester, Minnesota, USA

This book is a comprehensive survey of the field of medical imaging informatics. In addition to radiology, it also addresses other specialties such as pathology, cardiology, dermatology, and surgery, which have now adopted the use of digital images. The text discusses basic imaging informatics protocols, picture archiving and communication systems, and the electronic medical record. It also details key instrumentation and data mining technologies used in medical imaging informatics, as well as practical operational issues such as procurement, maintenance, teleradiology, and ethics. Catalog no. K11526, ISBN: 978-1-4398-3124-3 October 2011, 8-1/2 x 11, 367 pp. Suggested Price: $157.95 / £101.00 Also available as an eBook

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75


Interval-Censored Time-to-Event Data Methods and Applications Edited by

Ding-Geng (Din) Chen University of Rochester, New York, USA

Third Edition

Jianguo Sun

Svend Juul and Morten Frydenberg

University of Missouri, Columbia, USA

Aarhus University, Denmark

Karl E. Peace

This book continues to systematically cover data management, simple description and analysis, and more advanced analyses that are most often used in health research, such as regression models, survival analysis, measurement, and diagnosis. It also describes many graph types as well as how to modify the appearance of a graph. This third edition presents some of the new features in Stata 11, including the new, flexible syntax for factor variables. It also incorporates Stata 11 in the rewritten chapters on regression and survival analysis. Robust data sets can be downloaded from the book’s website.

Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, USA Chapman & Hall/CRC Biostatistics Series

Biostatistics

A practical guide for biomedical researchers, clinicians, biostatisticians, and graduate students in biostatistics, this volume covers the latest developments in the analysis and modeling of interval-censored time-to-event data. Top researchers from academia, biopharmaceutical industries, and government agencies show how up-to-date statistical methods are used in biopharmaceutical and public health applications. The book presents data from actual clinical trials and biomedical research, including breast cancer and HIV data sets. It also offers easy access to computational methods and R software packages.

Catalog no. N10327, ISBN: 978-1-59718-077-1 August 2010, 7 3/8 x 9 1/4, 340 pp., Soft Cover Suggested Price: $79.95 / £49.99

Catalog no. K14515, ISBN: 978-1-4665-0425-7 July 2012, 6-1/8 x 9-1/4, 433 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Textbook

Textbook

Introduction to Statistical Methods for Clinical Trials

An Introduction to Bayesian Biostatistics Gary L. Rosner M.D. Anderson Cancer Center, Houston, Texas, USA

Purushottam Laud Chapman & Hall/CRC Texts in Statistical Science

76

An Introduction to Stata for Health Researchers

With discussions on many recent developments in Bayesian methodologies, An Introduction to Bayesian Biostatistics considers statistical issues in biomedical research, allowing for greater collaborations between biostatisticians and biomedical researchers. The text presents biostatistical methods from a Bayesian perspective. It includes an overview of Bayesian statistics, a discussion of rates and proportions with applications in clinical and other population-based studies, recent developments in clinical trial design, methods for evaluating censored data and diagnostic tests, and problems resulting from multiple comparisons.

Edited by

Thomas D. Cook and David L DeMets University of Wisconsin, Madison, USA Chapman & Hall/CRC Texts in Statistical Science

This text provides a solid understanding of the various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. It covers basic experimental design, sample size, randomization procedures, interim and survival analyses, quality of life assessment, and longitudinal methods. The book describes all phases of a clinical trial and explores the advantages of and objections to the intent-to-treat principle as well as its implementation. With exercises at the end of most chapters, it also illustrates methods using examples with real data from a variety of disease areas, including heart and lung diseases, cancer, and AIDS. Catalog no. C0005, ISBN: 978-1-58488-027-1 November 2007, 8-1/2 x 11, 464 pp. Suggested Price: $85.95 / £55.99

Catalog no. K10026, ISBN: 978-1-4398-0008-9 June 2013, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $79.95 / £49.99 Also available as an eBook

Joint Models for Longitudinal and Time-to-Event Data Introduction to Medical Imaging Management Bernard Rubenzer Medical Technology Management Institute, Waukesha, Wisconsin, USA

This comprehensive book provides an in-depth overview of every major facet pertaining to the knowledge and skills necessary to become a department or imaging center supervisor or manager. The text follows a natural progression from transitioning into a management position and dealing with former peers through the most sophisticated skills uniquely applicable to medical imaging management. Covering all aspects of the profession—operations, human resources, finance, and marketing—this reference is a must-have for any potential, new, or less experienced imaging manager. Catalog no. K14126, ISBN: 978-1-4398-9183-4 January 2013, 6-1/8 x 9-1/4, 200 pp. Suggested Price: $89.95 / £57.99

With Applications in R Dimitris Rizopoulos Erasmus University Medical Center, Rotterdam, Netherlands Chapman & Hall/CRC Biostatistics Series

Longitudinal studies often investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest, e.g., prostate cancer studies where longitudinal PSA level measurements are collected in conjunction with the time-to-recurrence. This book provides a full treatment of joint models for longitudinal and time-to-event data. The content is explanatory rather than mathematically rigorous and applications are emphasized. All illustrations put forward are available in the R programming language via the freely available package JM written by the author. Catalog no. K13371, ISBN: 978-1-4398-7286-4 June 2012, 6-1/8 x 9-1/4, 275 pp. Suggested Price: $79.95 / £49.99 Also available as an eBook

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Lung Imaging and Computer Aided Diagnosis Edited by

Medical Infrared Imaging Principles and Practices Edited by

Mary Diakides Advanced Concepts Analysis, Inc., Falls Church, Virginia, US

Ayman El-Baz

Joseph D. Bronzino

University of Louisville, Kentucky, USA

Simsbury, Connecticut, USA

Global Biomedical Technologies, Inc., California, USA

Donald R. Peterson

There is an urgent need for new technology to diagnose small, malignant lung nodules early as well as large nodules located away from large diameter airways because current technology—namely, needle biopsy and bronchoscopy—fail to diagnose those cases. This book brings together researchers in pulmonary image analysis to discuss state-of-the-art image processing techniques for detecting and diagnosing lung cancer at an early stage. The book addresses variables and discrepancies in scans and proposes ways of evaluating small lung masses more consistently to allow for more accurate measurement of growth rates and analysis of shape and appearance of the detected lung nodules.

This book explores new ideas, concepts, and technologies such as dynamic thermal imaging, thermal texture mapping, and thermal multispectral imaging commonly used in the clinical environment. The coverage ranges from historical background, concepts, clinical applications, standards, and infrared technology. Of interest to the medical and biomedical engineering communities, the book can provide many opportunities for developing and conducting multidisciplinary research in many areas of medical infrared imaging.

Catalog no. K12032, ISBN: 978-1-4398-4557-8 August 2011, 7 x 10, 496 pp. Suggested Price: $199.95 / £127.00

University of Connecticut, Farmington, USA

Catalog no. K13338, ISBN: 978-1-4398-7249-9 December 2012, 7 x 10, 638 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

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Textbook

Biostatistics

Jasjit S. Suri

Modelling Survival Data in Medical Research

Textbook

Medical Biostatistics

Second Edition

Third Edition

David Collett

Abhaya Indrayan

UK Transplant, Bristol, UK

Chapman & Hall/CRC Biostatistics Series

The third edition of this acclaimed reference focuses on the statistical aspects of medicine with a medical perspective, showing how biostatistics is a useful tool to manage some medical uncertainties. This edition includes several new topics, provides expanded coverage of many other topics and includes software illustrations. The author presents step-by-step explanations of statistical methods with the help of numerous real-world examples. Guide charts at the beginning of the book enable quick access to the relevant statistical procedure, and the comprehensive index at the end makes it easier to locate terms of interest. Figure slides are available upon qualifying course adoption

Catalog no. K13952, ISBN: 978-1-4398-8414-0 August 2012, 6-1/8 x 9-1/4, 1024 pp. Suggested Price: $129.95 / £82.00

Chapman & Hall/CRC Texts in Statistical Science

Profusely illustrated with examples and written in an easy-to-follow style, this practical guide begins with an introduction to survival analysis and a description of four studies that lead to survival data. Subsequent chapters then use those data sets and others to illustrate various analytical techniques applicable to such data. This second edition features a more detailed treatment of parametric models, accelerated failure time models, and analysis of interval-censored data. It also illustrates methods using SAS to generate and examine output in detail. Catalog no. C3251, ISBN: 978-1-58488-325-8 March 2003, 6-1/8 x 9-1/4, 408 pp., Soft Cover Suggested Price: $83.95 / £52.99

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Also available as an eBook

Medical Imaging Principles and Practices Edited by

Mostafa Analoui The Livingston Group, Madison, Wisconsin, USA

MRI

Joseph D. Bronzino

Essentials for Innovative Technologies

Simsbury, Connecticut, USA

Giuseppe Placidi

Donald R. Peterson University of Connecticut, Farmington, USA

This book offers a selective review of key imaging modalities focusing on modalities with established clinical utilization. It provides a detailed overview of x-ray imaging and computed tomography, fundamental concepts in signal acquisition and processes, followed by an overview of functional MRI (fMRI) and chemical shift imaging. It also covers topics in Magnetic Resonance Microcopy, the physics of instrumentation and signal collection, and their application in clinical practice. The selection of topics provides readers with an appreciation of the depth and breadth of the field and the challenges ahead of the technical and clinical community of researchers and practitioners. Catalog no. K13254, ISBN: 978-1-4398-7102-7 October 2012, 7 x 10, 454 pp. Suggested Price: $99.95 / £63.99

University of L’Aquila, Italy

This book describes innovative methods to improve magnetic resonance imaging (MRI) beyond its current limitations. The author proposes smart encoding methods and acquisition sequences to deal with frequency displacement due to residual static magnetic field inhomogeneity, motion, and undersampling. After a concise review of basic mathematical tools and the physics of MRI, the book describes each limitation and then proposes solutions for overcoming it. Requiring few or no hardware modifications, these speculative methods represent building blocks for more advanced MRI applications. The book also looks to the future of MRI. Catalog no. K11872, ISBN: 978-1-4398-4040-5 May 2012, 6-1/8 x 9-1/4, 216 pp. Suggested Price: $89.95 / £49.99 Also available as an eBook

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Multi-Detector CT Imaging Handbook

Multiple Testing Problems in Pharmaceutical Statistics Edited by

Alex Dmitrienko

Edited by

Quintiles Innovation, Overland Park, Kansas, USA

Luca Saba University of Cagliari, Italy

Jasjit S. Suri Global Biomedical Technologies, Inc., California, USA

Biostatistics

A comprehensive review or the latest research in computed tomography (CT), this book covers its engineering and clinical benefits in diagnosis of human pathologies, including the protocols and potentialities of advanced tomography scanning with very high-quality CT images. With contributions from world-class experts, the book examines all aspects of CT technologies related to neck-brain, cardiovascular systems, thorax, abdomen and GI system, pelvis and urinary system, musculo-scheletric systems and special applications. It also provides coverage of CAD applications to CT along with a discussion of the potential dangers of CT in terms of over-radiation, particularly related to children. Catalog no. K14200, ISBN: 978-1-4398-9399-9 June 2013, 7 x 10, 350 pp. Suggested Price: $279.95 / £178.00 Also available as an eBook

Ajit C. Tamhane Northwestern University, Evanston, Illinois, USA

Frank Bretz Novartis Pharma AG, Basel, Switzerland Chapman & Hall/CRC Biostatistics Series

Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, this volume explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications. It describes important multiplicity problems encountered in pre-clinical and clinical trial settings. The book includes numerous case studies from actual pre-clinical experiments and clinical trials to help readers quickly learn common multiple testing methods and apply them to real-life problems. It also reviews relevant regulatory guidelines and implements the methods using SAS and R. The data sets and code are available on the book’s website. Catalog no. C9845, ISBN: 978-1-58488-984-7 December 2009, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $93.95 / £62.99 Also available as an eBook

Multi-Detector CT Imaging Abdomen, Pelvis and CAD Applications Edited by

University of Cagliari, Italy

Multivariate Survival Analysis and Competing Risks

Jasjit S. Suri

Martin J. Crowder

Luca Saba

Global Biomedical Technologies, Inc., California, USA

78

Imperial College, University of London, UK

Updating the popular first edition, this book offers comprehensive detail on the latest research findings in the field of computed tomography (CT) Imaging. Written by some of the world’s top experts in the field, this volume focuses on the engineering and clinical benefits of using CT technologies to diagnose human pathologies. It covers every major body system, detailing the protocols and potentialities of advanced CT scanning using very high-quality CT images. This book will benefit professionals and graduate-level students in areas including radiology, neuroradiology, cardiology, oncology, orthopedics, and biomedical engineering.

Suitable for graduate students and researchers in statistics and biostatistics as well as those in the medical field, epidemiology, and social sciences, this book introduces univariate survival analysis and extends it to the multivariate case. It also covers competing risks and counting processes and provides many real-world examples, exercises, and R code. The text discusses survival data, survival distributions, frailty models, parametric methods, multivariate data and distributions, copulas, continuous failure, parametric likelihood inference, and non- and semi-parametric methods.

Catalog no. K14199, ISBN: 978-1-4398-9397-5 June 2013, 7 x 10, 600 pp. Suggested Price: $179.95 / £114.00

Catalog no. K13489, ISBN: 978-1-4398-7521-6 April 2012, 6-1/8 x 9-1/4, 417 pp. Suggested Price: $99.95 / £63.99

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Chapman & Hall/CRC Texts in Statistical Science

Multi-Detector CT Imaging Principles, Head, Neck, and Vascular Systems Edited by

Nanoimaging

Luca Saba

Edited by

University of Cagliari, Italy

Beth A. Goins and William T. Phillips

Jasjit S. Suri

University of Texas, San Antonio, USA

Global Biomedical Technologies, Inc., California, USA

Series: Pan Stanford Series on Biomedical Nanotechnology

This comprehensive reference work details the latest research and findings in computed tomography (CT) imaging. Addressing every major body system, the first volume of this text details the engineering and clinical benefits in the diagnosis of human pathologies utilizing CT technologies. The text presents CAD principles as applied to CT and also covers the protocols and potentialities of advanced computed tomography scanning with high-quality CT images. The contributors are world-class experts from a number of different countries.

The first resource of its kind, this book covers cutting-edge research on the use of nanoparticles for in vivo diagnostic medical imaging and therapy. It discusses a variety of nanoparticles, including quantum dots, carbon nanotubes, dendrimers, gold nanoshells, metal nanorods, micelles, liposomes, polymers, MRI iron oxide particles, and microbubbles. Examples in the book include multifunctional nanoparticles that designed for multimodality imaging and simultaneous diagnostic and therapy (theranostic) applications.

Catalog no. K14192, ISBN: 978-1-4398-9380-7 June 2013, 7 x 10, 600 pp. Suggested Price: $179.95 / £114.00

Catalog no. N10430, ISBN: 978-981-4267-09-0 September 2011, 7 x 10, 350 pp. Suggested Price: $149.95 / £95.00

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Practical Statistical Methods

Second Edition

A SAS Programming Approach

Guy Cox

Lakshmi Padgett

University of Sydney, New South Wales, Australia

Centocor, Malvern, Pennsylvania, USA

This reference on optical imaging techniques covers the field from the basics of the optical microscope to highly advanced techniques such as Förster resonant energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM). Using a uniform style and format, it provides an understanding of the underlying principles, so readers can learn the benefits and limitations of each technique described. Topics covered include: optical contrasting techniques, fluorescence and fluorescence microscopes, three-dimensional imaging, the confocal microscope, nonlinear microscopy, advanced fluorescence techniques, and breaking the diffraction limit. Chapters include suggestions for further reading.

This book presents a broad spectrum of statistical methods useful for researchers without an extensive statistical background. Omitting mathematical details and complicated formulae, it provides SAS programs to carry out the necessary analyses and draw appropriate inferences for common statistical problems. The author describes methods used for quantitative data and continuous data following normal and non-normal distributions. She also focuses on simple linear regression, logistic regression, and the proportional hazards model. The final chapter briefly discusses such miscellaneous topics as propensity scores, misclassification errors, interim analysis, conditional power, bootstrap, and jackknife.

Catalog no. K12150, ISBN: 978-1-4398-4825-8 June 2012, 6-1/8 x 9-1/4, 316 pp. Suggested Price: $149.95 / £95.00

Catalog no. K10634, ISBN: 978-1-4398-1282-2 April 2011, 6-1/8 x 9-1/4, 304 pp. Suggested Price: $83.95 / £52.99

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Biostatistics

Optical Imaging Techniques in Cell Biology

Textbook

Optimal Design for Nonlinear Response Models

Practical Statistics for Medical Research

Valerii V. Fedorov and Sergei L. Leonov

Douglas G. Altman

GlaxoSmithKline, Collegeville, Pennsylvania, USA

Centre for Statistics in Medicine, Oxford, UK

Chapman & Hall/CRC Biostatistics Series

Chapman & Hall/CRC Texts in Statistical Science

This book examines the theory of optimal model-based design and provides examples of optimal designs for various models, mostly related to biopharmaceutical applications, such as dose-response studies. The authors pay special attention to adaptive or sequential optimal designs for nonlinear regression models when estimation and optimal design are performed in stages. Ideal for researchers in regression analysis and experimental design, the text illustrates optimal designs for various models using an example of the application of a first-order optimization algorithm in the space of information matrices, which is implemented in both MATLAB® and SAS.

Practical Statistics for Medical Research is a problem-based text for medical researchers, medical students, and others in the medical arena who need to use statistics but have no specialized mathematics background. The author draws on 20 years of experience as a consulting medical statistician to provide clear explanations to key statistical concepts, with a firm emphasis on practical aspects of designing and analyzing medical research. Using real data and including dozens of interesting data sets, this bestselling text gives special attention to the presentation and interpretation of results and the many real problems that arise in medical research.

Catalog no. K11140, ISBN: 978-1-4398-2151-0 February 2013, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $89.95 / £57.99

Catalog no. C7630, ISBN: 978-0-412-27630-9 November 1990, 6-1/8 x 9-1/4, 624 pp. Suggested Price: $109.95 / £69.99

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Textbook

Physics of Mammographic Imaging

Regression Models as a Tool in Medical Research

Edited by

Werner Vach

Mia K. Markey

Institute of Medical Biometry and Medical Informatics, Freiburg, Germany

The University of Texas at Austin, USA

A comprehensive treatment of developments in this field, this book covers the fundamentals of image formation, image interpretation, analysis, and modeling. It includes coverage of the use of mammographic imaging in the detection, diagnosis, treatment planning, and monitoring of breast cancer. Expert authors give a balanced summary of core topics such as digital mammography, contrastenhanced, stereomammography, breast tomosynthesis, and breast CT. The book highlights the use of mammographic imaging with complementary breast imaging modalities such as ultrasound, MRI, and nuclear medicine techniques. It discusses critical issues such as computer-aided diagnosis, perception, and quality assurance.

While regression models have become standard tools in medical research, understanding how to properly apply the models and interpret the results is often challenging for beginners. This text presents the fundamental concepts and important aspects of regression models most commonly used in medical research, including the classical regression model for continuous outcomes, the logistic regression model for binary outcomes, and the Cox proportional hazards model for survival data. The author emphasizes adequate use, correct interpretation of results, appropriate presentation of results, and avoidance of potential pitfalls.

Catalog no. K13500, ISBN: 978-1-4398-7544-5 November 2012, 8-1/2 x 11, 319 pp. Suggested Price: $179.95 / £114.00

Catalog no. K15111, ISBN: 978-1-4665-1748-6 December 2012, 6-1/8 x 9-1/4, 495 pp. Suggested Price: $89.95 / £57.99

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A solutions manual and figure slides are available upon qualifying course adoption

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79


Sample Size Calculations in Clinical Research Second Edition Shein-Chung Chow Duke University School of Medicine, Durham, North Carolina, USA

Jun Shao

Statistical Thinking in Epidemiology

University of Wisconsin, Madison, USA

Yu-Kang Tu and Mark S. Gilthorpe

Hansheng Wang

University of Leeds, UK

Peking University, Beijing, China

Addressing issues that have plagued researchers throughout the last decade, this book provides new insights into the many existing problems in statistical modeling and offers several alternative strategies to approach these problems. Emphasizing the importance of statistical thinking behind all analyses, the authors use specific examples in epidemiology to illustrate different model specifications that can imply different sets of causal relationships between variables. Each model is interpreted with regard to the context of implicit or explicit causal relationships. The authors also use vector geometry where applicable to provide an intuitive understanding of important statistical concepts.

Chapman & Hall/CRC Biostatistics Series

Biostatistics

This book explains how the formulas and procedures for sample size calculations can be used in a variety of clinical research and development stages. It presents real-world examples from several therapeutic areas to illustrate clinical and statistical concepts, interpretations, and interactions. The book also explores emerging topics in pharmaceutical research and development, including QT/ QTc studies with time-dependent replicates and the use of propensity score analysis in nonrandomized or observational studies. This edition now provides sample size calculations for three major areas of clinical research: dose response studies, microarray studies, and Bayesian approaches. Catalog no. C9829, ISBN: 978-1-58488-982-3 August 2007, 6-1/8 x 9-1/4, 480 pp. Suggested Price: $99.95 / £62.99

Catalog no. K10018, ISBN: 978-1-4200-9991-1 July 2011, 6-1/8 x 9-1/4, 231 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

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Textbook

Statistical and Computational Methods in Brain Image Analysis Moo K. Chung

80

A major challenge in brain mapping is caused by the massive amount of nonstandard high dimensional data that is difficult to analyze using standard techniques. This book covers modern statistical and computational techniques for analyzing such data. Some methodological topics covered include finite mixture models, logistic models, nonparametric regression, mixed effects models, neural networks, and support vector machines. Real datasets are used to illustrate the methods described and MATLAB code to implement them. The book has an accompanying website where this material can be downloaded. Catalog no. K11644, ISBN: 978-1-4398-3635-4 June 2013, 6-1/8 x 9-1/4, 416 pp. Suggested Price: $99.95 / £63.99

Statistics for Epidemiology Nicholas P. Jewell University of California, Berkeley, USA Chapman & Hall/CRC Texts in Statistical Science

Written by one of the top biostatisticians in the field, Statistics for Epidemiology fills a substantial niche by explaining the ideas behind the analysis of epidemiological data without requiring a high level of mathematics or resorting to a “cookbook” format. It covers the basic material for analyzing data that arise from simple epidemiological studies, including case-control and matched studies. Methodologically, it describes stratification techniques for handling confounding and interaction and the logistic regression model. The author uses a case-study approach, following a few simple examples through several method chapters rather than introducing a different example at each stage. Catalog no. C4339, ISBN: 978-1-58488-433-0 August 2003, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $99.95 / £62.99

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Statistical Evaluation of Diagnostic Performance Topics in ROC Analysis

Statistics of Medical Imaging

Kelly H. Zou, Aiyi Liu, Andriy I. Bandos, Lucila Ohno-Machado, and Howard E. Rockette

Tianhu Lei

Chapman & Hall/CRC Biostatistics Series

This book presents innovative approaches in Receiver Operating Characteristic (ROC) analysis, which are relevant to a wide variety of applications, including medical imaging, cancer research, epidemiology, and bioinformatics. The covered topics include monotone-transformation techniques in parametric ROC analysis, ROC methods for combined and pooled biomarkers, Bayesian hierarchical transformation models, sequential designs and inferences in the ROC setting, predictive modeling, multireader ROC analysis, and free-response ROC (FROC) methodology.

Statistical investigation into technology not only provides a better understanding of the intrinsic features of the technology (analysis), but also leads to an improved design of the technology (synthesis). Physical principles and mathematical procedures of medical imaging technologies have been extensively studied during past decades. However, less work has been done on their statistical aspect. Filling this gap, this book provides a theoretical framework for statistical investigation into medical technologies. Rather than offer detailed descriptions of statistics of basic imaging protocols of x-ray CT and MRI, the book presents a method to conduct similar statistical investigations into more complicated imaging protocols.

Catalog no. K10617, ISBN: 978-1-4398-1222-8 July 2011, 6-1/8 x 9-1/4, 245 pp. Suggested Price: $93.95 / £59.99

Catalog no. C8842, ISBN: 978-1-4200-8842-7 December 2011, 6-1/8 x 9-1/4, 438 pp. Suggested Price: $104.95 / £66.99

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Series: Chapman & Hall/CRC Interdisciplinary Statistics

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The Fluorescent Protein Revolution Indiana University, Indianapolis, USA

Mutiscale Extensions and Biological Applications

Michael W. Davidson

Marco Scianna and Luigi Preziosi

Florida State University, Tallahassee, USA

Politecnico di Torino, Italy

Richard N. Day

Series in Cellular and Clinical Imaging

Series: Chapman & Hall/CRC Mathematical & Computational Biology

This reference discusses major advances in the development of novel imaging techniques that exploit new probes. It describes the photophysical properties of new fluorescent probes, particularly the important red fluorescent probes from corals. The book gives a detailed account of state-of-the-art imaging methods that exploit the characteristics of new probes. It also illustrates the applications of fluorescent probes in a variety of different optical techniques, including superresolution microscopy. Many figures throughout the text further clarify concepts.

This book presents the multiscale developments and application of the cellular Potts model (CPM) in biological phenomena. It discusses the biophysical basis and history of the CPM, important multiscale extensions of the approach, and several applications of the extensions. For each application, the authors include a biological presentation of the problem, a formulation of the relative CPM, the main results, and references to further reading. They also illustrate the computational implementation of the CPM and offer ways to extend it to increase the realism of the simulations.

Catalog no. K13481, ISBN: 978-1-4398-7508-7 April 2013, 7 x 10, 400 pp. Suggested Price: $129.95 / £82.00

Catalog no. K15009, ISBN: 978-1-4665-1478-2 March 2013, 6 x 9, 300 pp. Suggested Price: $89.95 / £57.99

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Data Mining in Biomedical Imaging, Signaling, and Systems Edited by

Theory of Drug Development Eric B. Holmgren

Sumeet Dua Louisiana Tech University, Ruston, USA

Rajendra Acharya U Ngee Ann Polytechnic, Singapore

Chapman & Hall/CRC Biostatistics Series

During drug development, pharmaceutical companies test new molecules and assemble the necessary evidence required by regulatory agencies to show that a drug is safe and effective. This book presents a quantitative framework for evaluating the efficiency of the drug development process as well as the quality of the resulting evidence supporting clinical efficacy. Using this framework, the author formally evaluates a variety of issues that arise in drug development, from surrogate variables, targeted therapies, and interim analysis to seamless phase II/III designs. Catalog no. K14671, ISBN: 978-1-4665-0746-3 June 2013, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

This comprehensive volume demonstrates the broad scope of uses for data mining and includes detailed strategies and methodologies for analyzing data from biomedical images, signals, and systems. Written by experts in the field, it presents data mining techniques in the context of various important clinical issues, including diagnosis and grading of depression, identification and classification of arrhythmia and ischemia, and description of classification paradigms for mammograms. The book provides ample information and techniques to benefit researchers, practitioners, and educators of biomedical science and engineering. Figure slides are available upon qualifying course adoption

Catalog no. K11798, ISBN: 978-1-4398-3938-6 May 2011, 6-1/8 x 9-1/4, 440 pp. Suggested Price: $115.95 / £69.99 Also available as an eBook

Textbook Textbook

Biological Computation Ehud Lamm

Differential Equations and Mathematical Biology Second Edition D. S. Jones

Tel-Aviv University, Israel

University of Dundee, Scotland

Ron Unger

M. J. Plank

Bar-Ilan University, Ramat-Gan, Israel Series: Chapman & Hall/CRC Mathematical & Computational Biology

A unified overview of computer science ideas inspired by biology, Biological Computation presents the most fundamental and significant concepts in this area. In the book, readers discover profound ideas about computer science through biological examples, such as the use of DNA for performing computations and how evolution solves optimization problems. The text focuses on cellular automata, evolutionary computation, neural networks, and molecular computation. Each chapter explores the biological background, describes the computational techniques, gives examples of applications, discusses possible variants of the techniques, and includes exercises and solutions. Figure slides are available upon qualifying course adoption

Catalog no. C7959, ISBN: 978-1-4200-8795-6 May 2011, 6-1/8 x 9-1/4, 343 pp. Suggested Price: $79.95 / £49.99

Biostatistics / Mathematics for Biology and Medicine

Cellular Potts Models

Edited by

University of Canterbury, Christchurch, New Zealand

B. D. Sleeman University of Leeds, UK Series: Chapman & Hall/CRC Mathematical & Computational Biology

Ideal for courses on differential equations with applications to mathematical biology or as an introduction to mathematical biology, this bestselling text introduces the fundamental modeling and analytical techniques used to understand biological phenomena. It discusses the modeling of biological behavior, including biochemical reactions, nerve pulses, predator–prey models, and epidemics. This expanded edition includes a new section on spiral waves, recent developments in tumor biology, and additional examples and exercises. Providing downloadable MATLAB® files online, it presents numerical solutions of differential equations and numerical bifurcation analysis. Catalog no. C8357, ISBN: 978-1-4200-8357-6 November 2009, 6-1/8 x 9-1/4, 462 pp. Suggested Price: $86.95 / £37.99

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81


Dynamical Models in Medicine

Game-Theoretical Models in Biology

Yang Kuang

Mark Broom

Arizona State University, Tempe, USA

City University, London, UK

John Nagy

Jan Rychtar

Scottsdale Community College, Arizona, USA

The University of North Carolina at Greensboro, USA

Textbook

Mathematics for Biology and Medicine 82

Series: Chapman & Hall/CRC Mathematical & Computational Biology

Series: Chapman & Hall/CRC Mathematical & Computational Biology

This self-contained book focuses on three categories of disease: cancer, viral, and dynamic. It presents the medical and biological background of these diseases, specific issues for modeling, and existing methods and their limitations. It introduces mathematical and programming tools, along with analytical and numerical studies of models. It provides end-of-chapter exercises and projects, hints and answers to selected problems at the back of the book, and a supplementary website with lecture notes, homework problems, useful computer programs, and other reference material.

This book covers evolutionary games in biology with a focus on classical evolutionary games. The authors first present a brief mathematical introduction for those new to evolutionary game theory and then outline key mathematical developments in order to provide a solid understanding of the fundamentals. Next, the text discusses a range of applications of game theory, introducing the biological problem, the details of the most important models, and the conclusions in each case. Each section relates the games to ones already introduced earlier in the book.

Catalog no. C990X, ISBN: 978-1-58488-990-8 April 2013, 6-1/8 x 9-1/4, 500 pp. Suggested Price: $79.95 / £49.99

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Catalog no. K12455, ISBN: 978-1-4398-5321-4 February 2013, 6-1/8 x 9-1/4, 528 pp. Suggested Price: $79.95 / £39.99 Also available as an eBook

Textbook

Textbook

Dynamics of Biological Systems

An Introduction to Stochastic Processes with Applications to Biology

Michael Small

Second Edition

Hong Kong Polytechnic University

Linda J. S. Allen

Series: Chapman & Hall/CRC Mathematical & Computational Biology

Texas Tech University, Lubbock, USA

With exercises and projects in each chapter, this classroom-tested text shows how to apply a variety of mathematical and computational techniques to model and analyze the temporal and spatial phenomena of biological systems. The mathematical models and computer simulations offer insight into cardiac pacemakers, artificial electrical defibrillation, pandemics, pattern formation, flocking behavior, the interaction of autonomous agents, and hierarchical and structured network topologies. MATLAB® implementations of algorithms and case studies are available on the author’s website.

Focusing on discrete and continuous time Markov chains and continuous time and state Markov processes, this text presents the basic theory of stochastic processes necessary to understand and apply stochastic methods to biological problems. This edition contains a new chapter on stochastic differential equations that extends basic theory to multivariate processes. Along with additional references, it now includes examples and exercises from cellular and molecular biology and doubles the number of exercises and MATLAB® programs at the end of each chapter.

A solutions manual and figure slides are available upon qualifying course adoption

An instructor’s manual and figure slides are available upon qualifying course adoption

Catalog no. K12463, ISBN: 978-1-4398-5336-8 August 2011, 6-1/8 x 9-1/4, 284 pp. Suggested Price: $79.95 / £49.99

Catalog no. K10993, ISBN: 978-1-4398-1882-4 December 2010, 6-1/8 x 9-1/4, 490 pp. Suggested Price: $93.95 / £41.99

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Textbook

Dynamics of the Chemostat A Bifurcation Theory Approach Abdelhamid Ajbar and Khalid Alhumaizi

An Introduction to Systems Biology Design Principles of Biological Circuits Uri Alon Weizmann Institute of Science, Rehovot, Israel

King Saud University, Riyadh, Saudi Arabia

Series: Chapman & Hall/CRC Mathematical & Computational Biology

Based on the authors’ extensive work in this field, this book explores the use of bifurcation theory to analyze the static and dynamic behavior of the chemostat. It presents a systematic, simple, and unified mathematical framework using singularity theory and bifurcation techniques. The authors cover a variety of case studies ranging from simple microbial growth to dynamics of interacting species to dynamics with product formation. They also address the connections between the design and control of the chemostat within the framework of singularity theory.

Highlighting simple, recurring circuit elements that make up a network, this book presents recently discovered design principles that govern the structure and behavior of biological networks such as gene circuits. It provides a quantitative theory for which circuits are found in a given environment and a mathematical framework for understanding and even designing biological circuits. Requiring only basic mathematics, it includes a review of necessary background material and introduces the concepts, principles, and mathematical tools that will drive future developments in the field.

Catalog no. K13016, ISBN: 978-1-4398-6714-3 August 2011, 6-1/8 x 9-1/4, 368 pp. Suggested Price: $104.95 / £66.99

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Catalog no. C6420, ISBN: 978-1-58488-642-6 July 2006, 7 x 10, 320 pp., Soft Cover Suggested Price: $62.95 / £39.99

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Essays in Mathematics Edited by

R. Sujatha Tata Institute of Fundamental Research, Mumbai, India

H. N. Ramaswamy

A Handbook of Applied Statistics in Pharmacology Katsumi Kobayashi National Institute of Technology and Evaluation, Tokyo, Japan

University of Mysore, India

K. Sadasivan Pillai

C. S. Yogananda Sri Jayachamarajendra College of Engineering, Mysore, India

This collection of essays spans pure and applied mathematics. Readers interested in mathematical research and historical aspects of mathematics will appreciate the enlightening content of these essays. Highlighting the pervasive nature of mathematics today in different areas, the book also covers the spread of mathematical ideas and techniques in areas ranging from computer science to physics to biology. Catalog no. N10373, ISBN: 978-1-57808-704-4 November 2011, 6-1/8 x 9-1/4, 350 pp., Soft Cover Suggested Price: $49.95 / £31.99 Also available as an eBook

Frontier Life Sciences Services, Chennai, India

Statistics plays an important role in pharmacology and related subjects such as toxicology and drug discovery and development. Improper statistical tool selection to analyze the data obtained from studies conducted in these subjects may result in wrongful interpretation of the performance or safety of drugs. This book communicates statistical tools in simple language. The examples used in the book are similar to those that the scientists encounter regularly in their research area. The authors have provided cognitive clues for selection of an appropriate statistical tool to analyse the data obtained from the studies and how to interpret the result of the statistical analysis. Catalog no. K16056, ISBN: 978-1-57808-752-5 October 2012, 6-1/8 x 9-1/4, 230 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Advanced Risk Analysis in Engineering Enterprise Systems

Textbook

Paul R. Garvey

Introduction to Statistical Data Analysis for the Life Sciences

The MITRE Corporation, Bedford, Massachusetts, USA

Claus Thorn Ekstrøm and Helle Sørensen

Cesar Ariel Pinto Old Dominion University, Norfolk, Virginia, USA

Statistics: A Series of Textbooks and Monographs

University of Copenhagen, Denmark

This book gives you advanced methods for tackling risk problems at the enterprise level. It focuses on the modeling, analysis, and management of risk in today’s complex engineering enterprise systems. The text presents a risk analytical framework for engineering enterprise systems and covers capability portfolio risk management, functional dependency network analysis, and extreme-event theory. It also discusses prioritization systems in highly networked enterprise environments and examines how to measure risks of extreme latencies in complex queuing networks.

Developed from the authors’ courses at the University of Copenhagen, this text provides a computational toolbox that enables readers to perform actual analysis for real data sets as well as the confidence and skills to undertake progressively more sophisticated analyses. Though accessible with any statistical software, the text encourages a reliance on R. The authors provide a short tutorial for those new to the software and include R commands and output at the end of each chapter. Data sets are available on a supporting website.

Catalog no. K11256, ISBN: 978-1-4398-2614-0 October 2012, 6-1/8 x 9-1/4, 464 pp. Suggested Price: $99.95 / £63.99

Catalog no. K11221, ISBN: 978-1-4398-2555-6 August 2010, 6-1/8 x 9-1/4, 427 pp., Soft Cover Suggested Price: $72.95 / £33.99

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Analysis of Capture-Recapture Data Byron J. T. Morgan University of Kent, Canterbury, UK

A solutions manual is available upon qualifying course adoption

Textbook

Modelling and Quantitative Methods in Fisheries

Rachel S. McCrea

Second Edition

University of Kent, Canterbury, UK

Malcolm Haddon

Series: Chapman & Hall/CRC Interdisciplinary Statistics

CSIRO, Hobart, Tasmania, Australia

Written for researchers and graduate students in statistics, demography, and the social sciences, this reference provides an overview of capture-recapture—the statistical methods used to estimate population size. It covers model development and examines the technicalities of model diagnostics, an often overlooked aspect in practice. The authors provide examples and exercises to demonstrate the statistical nuances that are encountered with complex modeling. They use realworld data sets throughout the text and include stand-alone software programs, such as R and WinBUGS.

Revised and restructured, this second edition provides an accessible introduction to quantitative methods in fisheries. It features new material on tests and comparisons as well as new chapters on length-based models and uncertainty estimation using Bayesian methods. Employing a structured, logical, step-by-step approach this text covers a range of topics including simple linear regression, complex nonlinear modeling, methodology, and specific fields in fisheries. It also includes numerous real-world examples implemented in Excel, with workbooks for all examples available for download on the web.

Catalog no. K11653, ISBN: 978-1-4398-3659-0 April 2013, 6-1/8 x 9-1/4, 256 pp. Suggested Price: $79.95 / £49.99

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Catalog no. C561X, ISBN: 978-1-58488-561-0 March 2011, 6-1/8 x 9-1/4, 465 pp. Suggested Price: $83.95 / £41.99 Also available as an eBook

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Math for Biology and Medicine / Statistics for Biological Science

Math Unlimited

83


Statistics for Biological Science / Statistical Theory and Methods 84

Textbook

Bayesian Methods Textbook

Multivariate Statistical Methods

A Social and Behavioral Sciences Approach, Second Edition

A Primer, Third Edition

Jeff Gill

Bryan F.J. Manly

Series: Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences

Western EcoSystem Technology, Inc., Laramie, Wyoming, USA

This is a thoroughly revised, updated edition of a best-selling introductory textbook and primer. The third edition retains the author’s trademark clear, concise style and focus on examples in the biological and environmental sciences. New to this edition are fully updated references as well as additional examples and exercises from the social and environmental sciences. While not linking the book to any specific software package, the book now includes an appendix comparing and contrasting various statistical software packages, such as Stata, Statistica, SAS, and Genstat. Catalog no. C4142, ISBN: 978-1-58488-414-9 July 2004, 6-1/8 x 9-1/4, 224 pp., Soft Cover Suggested Price: $65.95 / £41.99

A Handbook of Statistical Analyses Using R Second Edition

Washington University, St. Louis, Missouri, USA

One of the few to offer a graduate-level introduction to Bayesian statistics for social scientists, this text provides detailed explanations of derivations and theories using a computationally oriented approach. This edition presents many new developments in the field, such as the deviance information criterion, hybrid MCMC algorithms, diagnostics, perfect sampling, and Bayesian nonparametrics. The author emphasizes applications commonly used in the social sciences, including regression models and covariates, and uses the most up-to-date MCMC package in WinBUGS and the new MCMCpack in R. He also supplies detailed advice and guidance on the mechanics of stochastic simulation. A solutions manual is available upon qualifying course adoption

Catalog no. C5629, ISBN: 978-1-58488-562-7 November 2007, 6-1/8 x 9-1/4, 752 pp. Suggested Price: $85.95 / £55.99

Textbook

Bayesian Methods

King’s College, University of London, UK

A Social and Behavioral Sciences Approach, Third Edition

Torsten Hothorn

Jeff Gill

Brian S. Everitt

Ludwig-Maximilians-Universität München, Germany

Like its bestselling predecessor, this second edition provides a guide to data analysis using the R system for statistical computing. This edition contains new chapters on graphical displays, generalized additive models, and simultaneous inference as well as a new section on generalized linear mixed models that completes the discussion on the analysis of longitudinal data where the response variable does not have a normal distribution. The authors include new examples and additional exercises in several chapters. They also offer a new version of the HSAUR package (HSAUR2), which is available from CRAN. Catalog no. C7933, ISBN: 978-1-4200-7933-3 July 2009, 6-1/8 x 9-1/4, 376 pp., Soft Cover Suggested Price: $62.95 / £40.99 Also available as an eBook

Washington University, St. Louis, Missouri, USA Series: Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences

This updated, bestselling book continues to be one of the only Bayesian statistics texts designed for social scientists. Incorporating new research and additional material, the third edition presents state-of-the-art guidance on Bayesian statistical computing. It emphasizes Markov chain Monte Carlo (MCMC) and computation with R and WinBUGS. Along with doubling the number of exercises, this edition covers time series, decision theory, nonparametric models, and mixture models. A solutions manual is available upon qualifying course adoption

Catalog no. K12896, ISBN: 978-1-4398-6248-3 May 2013, 7 x 10, 700 pp. Suggested Price: $75.95 / £48.99

Textbook

An Introduction to Generalized Linear Models Third Edition Annette J. Dobson University of Queensland, Herston, Australia

Adrian G. Barnett Queensland University of Technology, Kelvin Grove, Australia Chapman & Hall/CRC Texts in Statistical Science

Analysis of Messy Data Volume 1 Designed Experiments, Second Edition George A. Milliken and Dallas E. Johnson Kansas State University, Manhattan, USA

Including Stata, R, and WinBUGS code as well as chapters on Bayesian analysis, the third edition of a bestseller continues to provide a cohesive framework for statistical modeling. Emphasizing numerical and graphical methods, it enables readers to understand the unifying structure that underpins GLMs. The text discusses common concepts and principles of advanced GLMs, including nominal and ordinal regression, survival analysis, and longitudinal analysis. It contains numerous examples from business, medicine, engineering, and the social sciences and offers the data sets and solutions to the exercises online.

A bestseller for nearly 25 years, this book helps applied statisticians and researchers effectively analyze the kinds of nonstandard data sets encountered in the real world. Written by two long-time researchers and professors, this second edition has been fully updated to reflect the many developments that have occurred since the original publication. This edition includes several modern suggestions for multiple comparison procedures as well as additional examples of split-plot designs and repeated measures designs. It also uses SAS-GLM to analyze unbalanced effects models and SAS-MIXED and JMP to analyze data in random effects, mixed model, and repeated measures experiments.

Catalog no. C9500, ISBN: 978-1-58488-950-2 May 2008, 6-1/8 x 9-1/4, 320 pp., Soft Cover Suggested Price: $67.95 / £41.99

Catalog no. C3340, ISBN: 978-1-58488-334-0 March 2009, 7 x 10, 674 pp. Suggested Price: $97.95 / £61.99

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Textbook

Analysis of Mixed Data Edited by

Alexander R. de Leon

Bayesian Ideas and Data Analysis An Introduction for Scientists and Statisticians

Keumhee Carriè Carriere University of Alberta, Canada

Chapman & Hall/CRC Texts in Statistical Science

This is the first volume to date that provides a comprehensive, unified, and timely summary of the major advances in the field of mixed models. The book traces important developments, collates basic results, presents terminology and methodologies, and gives an overview of statistical research applications. It blends theory and methodology and illustrates concepts via data from different disciplines. Theoretical and data analyses exercises are included at the end of each chapter.

Emphasizing the use of WinBUGS and R to analyze real data, this text presents statistical tools to address scientific questions. It highlights foundational issues in statistics, the importance of making accurate predictions, and the need for scientists and statisticians to collaborate in analyzing data. The authors cover a large number of statistical models, explore numerical approximations via MCMC simulation, and include numerous exercises and real-world examples. The WinBUGS code provided offers a convenient platform to model and analyze a wide range of data.

Catalog no. K13979, ISBN: 978-1-4398-8471-3 January 2013, 7 x 10, 262 pp. Suggested Price: $89.95 / £57.99

Code and other materials are available on the books’ website, and figure slides are available upon qualifying course adoption

Catalog no. K10199, ISBN: 978-1-4398-0354-7 July 2010, 7 x 10, 516 pp. Suggested Price: $72.95 / £48.99

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Textbook

Applied Categorical and Count Data Analysis Wan Tang, Hua He, and Xin M. Tu University of Rochester, New York, USA Chapman & Hall/CRC Texts in Statistical Science

This self-contained text explains how to perform the statistical analysis of discrete data. It covers classic concepts and popular topics, such as contingency tables, logistic models, and Poisson regression models, along with modern areas that include models for zero-modified count outcomes, parametric and semiparametric longitudinal data analysis, reliability analysis, and methods for dealing with missing values. R, SAS, SPSS, and Stata programming codes are provided for all the examples, enabling readers to immediately experiment with the data in the examples. Figure slides are available upon qualifying course adoption

Catalog no. K10311, ISBN: 978-1-4398-0624-1 June 2012, 6-1/8 x 9-1/4, 384 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Bayesian Inference for Partially Identified Models Exploring the Limits of Limited Data Paul Gustafson University of British Columbia, Vancouver, Canada

Many observational studies in epidemiology and other disciplines face inherent limitations in study design and data quality, such as selection bias, unobserved variables, and poorly measured variables. Accessible to statisticians and researchers from various disciplines, this book presents an overview of Bayesian inference in partially identified models. It includes many examples to illustrate the methods and provides R code for their implementation on the book’s website. The author also addresses a number of open questions to stimulate further research in this area. Catalog no. K13182, ISBN: 978-1-4398-6939-0 June 2013, 6-1/8 x 9-1/4, 256 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Textbook

Applied Nonparametric Statistical Methods Fourth Edition

Textbook

Bayesian Methods for Data Analysis Third Edition

Peter Sprent

Bradley P. Carlin

Dundee University, Scotland

University of Minnesota, Minneapolis, USA

Nigel C. Smeeton Guy’s King & St. Thomas School of Medicine, London, UK Chapman & Hall/CRC Texts in Statistical Science

While preserving the clear, accessible style of previous editions, this fourth edition reflects the latest developments in computer-intensive methods that deal with intractable analytical problems and unwieldy data sets. This edition summarizes relevant general statistical concepts and introduces basic ideas of nonparametric or distribution-free methods. Designed experiments, including those with factorial treatment structures, are now the focus of an entire chapter. The book also expands coverage on the analysis of survival data and the bootstrap method. The new final chapter focuses on important modern developments. With numerous exercises, the text offers the student edition of StatXact at a discounted price. A solutions manual is available upon qualifying course adoption

Catalog no. C701X, ISBN: 978-1-58488-701-0 March 2007, 6-1/8 x 9-1/4, 544 pp. Suggested Price: $93.95 / £59.99

Statistical Theory and Methods

Ronald Christensen, Wesley O. Johnson, Adam J. Branscum, and Timothy E. Hanson

University of Calgary, Canada

Thomas A. Louis Johns Hopkins Bloomberg School of Public Health, Maryland, USA

This proven text provides an accessible introduction to the foundations and applications of Bayesian analysis. Broadening its scope to nonstatisticians, this edition concentrates more on hierarchical Bayesian modeling as implemented via MCMC methods and related data analytic techniques. It contains a readerfriendly introduction to hierarchical statistical modeling, a new chapter on Bayesian design that emphasizes Bayesian clinical trials, a completely revised and expanded section on ranking and histogram estimation, and a new case study on infectious disease modeling and the 1918 flu epidemic. This edition includes new data examples, corresponding R and WinBUGS code, and exercises. A solutions manual is available upon qualifying course adoption

Catalog no. C6978, ISBN: 978-1-58488-697-6 June 2008, 6-1/8 x 9-1/4, 552 pp. Suggested Price: $76.95 / £48.99 Also available as an eBook

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Textbook

Design and Analysis of Experiments with SAS

Flexible Imputation of Missing Data

John Lawson

Stef van Buuren

Brigham Young University, Provo, Utah, USA

TNO Quality of Life, Leiden, The Netherlands

Statistical Theory and Methods

Chapman & Hall/CRC Texts in Statistical Science

Series: Chapman & Hall/CRC Interdisciplinary Statistics

This textbook covers both classical ideas in experimental design and the latest research topics. It clearly discusses the objectives of a research project that lead to an appropriate design choice, the practical aspects of creating a design and performing experiments, and the interpretation of computer data analysis results. Using SAS 9.2 to illustrate the construction of experimental designs and analysis of data, the author presents many applications from the pharmaceutical, agricultural, industrial chemicals, and machinery industries. SAS code and ancillaries are available on the author’s website.

A practical guide for handling missing data, this book provides a flexible and accessible framework for multiple imputation along with strategies for obtaining effective solutions to these problems. The text is supported by many examples using real data taken from the author’s vast research involving missing data. All of the analyses can be replicated in R using the dedicated package MICE, which was developed by the author. Topics covered include multiple imputation, multivariate and univariate missing data, as well as issues of measurement, selection, and longitudinal data.

A solutions manual is available upon qualifying course adoption

Catalog no. K13103, ISBN: 978-1-4398-6824-9 March 2012, 6-1/8 x 9-1/4, 342 pp. Suggested Price: $89.95 / £57.99

Catalog no. C6060, ISBN: 978-1-4200-6060-7 May 2010, 6-1/8 x 9-1/4, 596 pp. Suggested Price: $99.95 / £66.99 Also available as an eBook

Exploratory Multivariate Analysis by Example Using R François Husson, Sébastien Lê, and Jérôme Pagès AGROCAMPUS OUEST, Rennes, France Series: Chapman & Hall/CRC Computer Science & Data Analysis

Full of real-world case studies and practical advice, this book focuses on four fundamental methods of multivariate exploratory data analysis that are most suitable for applications. It covers principal component analysis when variables are quantitative, correspondence analysis and multiple correspondence analysis when variables are categorical, and hierarchical cluster analysis. The authors take a geometric point of view that provides a unified vision for exploring multivariate data tables. All of the data sets and code are available on the book’s website.

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Also available as an eBook

Catalog no. K11614, ISBN: 978-1-4398-3580-7 November 2010, 6-1/8 x 9-1/4, 240 pp. Suggested Price: $87.95 / £56.99 Also available as an eBook

Gaussian Process Regression Analysis for Functional Data Jian Qing Shi University of Newcastle upon Tyne, UK

Taeryon Choi Korea University, Seoul, South Korea

This work presents nonparametric statistical methods for functional regression analysis, specifically the methods based on a Gaussian process prior in a functional space. The authors discuss functional data analysis, theoretical aspects based on the asymptotic properties of Gaussian process regression models, and new methodological developments for high dimensional data and variable selection. They also explore novel nonparametric statistical methods for curve prediction, curve clustering, functional ANOVA, and functional regression analysis of batch data, repeated curves, and non-Gaussian data. Some MATLAB® and C codes are available on the first author’s website. Catalog no. K11716, ISBN: 978-1-4398-3773-3 July 2011, 6-1/8 x 9-1/4, 216 pp. Suggested Price: $104.95 / £66.99 Also available as an eBook

Textbook

Extending the Linear Model with R

Textbook

Generalized Linear, Mixed Effects and Nonparametric Regression Models

An Introduction with R

Julian J. Faraway University of Bath, UK Chapman & Hall/CRC Texts in Statistical Science

Linear models form the foundation of a vast range of statistical methodologies. Julian J. Faraway’s critically acclaimed Linear Models with R thoroughly examined the different methods available, and showed in which situations each one applies. Following in those footsteps, his new book surveys the techniques that grow from the regression model, presenting three extensions to that framework: generalized linear models, mixed effect models, and nonparametric regression models. It provides a well-stocked toolbox of methodologies, and with its unique presentation of these very modern statistical techniques, holds the potential to break new ground in the way graduate-level courses in this area are taught. Catalog no. C424X, ISBN: 978-1-58488-424-8 December 2005, 6-1/8 x 9-1/4, 312 pp. Suggested Price: $93.95 / £48.99

Generalized Additive Models Simon Wood University of Bath, England, UK Chapman & Hall/CRC Texts in Statistical Science

Generalized Additive Models: An Introduction with R imparts a thorough understanding of the theory and practical applications of GAMs and related advanced models, enabling informed use of these flexible tools. The author’s approach is based on a framework of penalized regression splines, and he builds the necessary foundation through motivating chapters on linear and generalized linear models. Use of the freely available R software helps explain the theory and illustrates the practicalities of linear, generalized linear, and generalized additive models, as well as their mixed effect extensions. An R package containing the featured datasets is freely available on the Internet. Catalog no. C4746, ISBN: 978-1-58488-474-3 February 2006, 6-1/8 x 9-1/4, 410 pp. Suggested Price: $99.95 / £62.99

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Second Edition James W. Hardin University of South Carolina, Columbia, USA

Joseph M. Hilbe

Handbook of Parametric and Nonparametric Statistical Procedures Fifth Edition

California Institute of Technology, Pasadena, and Arizona State University, Tempe, USA

David J. Sheskin

This second edition of a bestseller incorporates comments and suggestions from a variety of sources, including the Statistics.com course on longitudinal and panel models taught by the authors. Along with doubling the number of endof-chapter exercises, this edition offers more thorough coverage of hypothesis testing and diagnostics, expands discussion of various models associated with GEE, and provides a new presentation of model selection procedures. Numerous examples are employed throughout the text, along with the software code used to create, run, and evaluate the models being examined.

Unsurpassed in accessibility, practicality, and scope, the fifth edition of this classic handbook provides up-to-date, in-depth coverage of more than 160 statistical procedures as well as both theoretical and practical statistical topics. Including two new chapters on statistical modeling, this updated fifth edition contains substantial new material on statistical quality control, meta-analysis and time series analysis. Each chapter presents at least one example of how to compute a statistical test and offers decision tables to help determine the appropriate test.

Catalog no. K13819, ISBN: 978-1-4398-8113-2 December 2012, 6-1/8 x 9-1/4, 278 pp. Suggested Price: $89.95 / £57.99

Western Connecticut State University, Danbury, USA

Catalog no. K12706, ISBN: 978-1-4398-5801-1 April 2011, 7 x 10, 1926 pp. Suggested Price: $169.95 / £115.00

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Generalized Latent Variable Modeling Multilevel, Longitudinal, and Structural Equation Models Anders Skrondal London School of Economics, UK

Handbook of Spatial Statistics Edited by

Alan E. Gelfand, Peter J. Diggle, Montserrat Fuentes, and Peter Guttorp Series: Chapman & Hall/CRC Handbooks of Modern Statistical Methods

Sophia Rabe-Hesketh University of California, Berkeley, USA Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability

Generalized Latent Variable Modeling: Multilevel, Longitudinal, and Structural Equation Models unifies and extends latent variable models, including multilevel or generalized linear mixed models, longitudinal or panel models, item response or factor models, latent class or finite mixture models, and structural equation models. Following a gentle introduction to latent variable modeling, the authors clearly explain a wide range of estimation and prediction methods. Exciting, realistic applications demonstrate how latent variable modeling can be used to solve problems in areas as diverse as medicine, economics, and psychology. Numerous displays, figures, and graphs make the text vivid and easy to read. Catalog no. C80007, ISBN: 978-1-58488-000-4 May 2004, 6-1/8 x 9-1/4, 528 pp. Suggested Price: $115.95 / £73.99

Based on the work of prominent researchers, this handbook provides broad, thorough coverage of this vibrant area, from historical to contemporary topics. It explores the modeling advances, computational approaches, and methodology that have emerged in recent years. The book focuses on continuous and discrete spatial variation, spatial point patterns, and spatio-temporal processes. It also covers multivariate spatial process models, spatial aggregation, spatial misalignment, and spatial gradients in depth. The theory and applications are illustrated with many real-world data examples. Catalog no. C7287, ISBN: 978-1-4200-7287-7 March 2010, 7 x 10, 619 pp. Suggested Price: $109.95 / £69.99 Also available as an eBook

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Hidden Markov Models for Time Series

Handbook of Markov Chain Monte Carlo

An Introduction Using R

Edited by

Steve Brooks, Andrew Gelman, Galin L. Jones, and Xiao-Li Meng Series: Chapman & Hall/CRC Handbooks of Modern Statistical Methods

Handbook of Markov Chain Monte Carlo brings together the major advances that have occurred in recent years while incorporating enough introductory material for new users of MCMC. Along with thorough coverage of the theoretical foundations and algorithmic and computational methodology, this comprehensive handbook includes substantial realistic case studies from a variety of disciplines. These case studies demonstrate the application of MCMC methods and serve as a series of templates for the construction, implementation, and choice of MCMC methodology. Figure slides are available upon qualifying course adoption

Catalog no. C7941, ISBN: 978-1-4200-7941-8 May 2011, 7 x 10, 619 pp. Suggested Price: $104.95 / £66.99

Statistical Theory and Methods

Generalized Estimating Equations

Walter Zucchini University of Gottingen, Germany

Iain L. MacDonald University of Cape Town, South Africa Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability

This book illustrates the wonderful flexibility of HMMs as general-purpose models for time series data. It presents an accessible overview of HMMs for analyzing time series data, from continuous-valued, circular, and multivariate series to binary data, bounded and unbounded counts, and categorical observations. It explores a variety of applications in animal behavior, finance, epidemiology, climatology, and sociology. The authors discuss how to employ the freely available computing environment R to carry out computations for parameter estimation, model selection and checking, decoding, and forecasting. They provide all of the data sets analyzed in the text online. Catalog no. C5734, ISBN: 978-1-58488-573-3 April 2009, 6 x 9, 288 pp. Suggested Price: $86.95 / £53.99 Also available as an eBook

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Hierarchical Modeling and Analysis for Spatial Data Sudipto Banerjee University of Minnesota, Minneapolis, USA

Alan E. Gelfand Duke University, Durham, North Carolina, USA

Bradley P. Carlin University of Minnesota, Minneapolis, USA Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability

Statistical Theory and Methods

Hierarchical Modeling and Analysis for Spatial Data is the first accessible, upto-date treatment of Bayesian methods, modeling, and data analysis for spatial and spatio-temporal data. Self-contained, it includes overviews of the necessary background material, exercises, and brief tutorial on using S+SpatialStats, geoR, and WinBUGS software for hierarchical spatial modeling. This book provides clear explanations, plentiful illustrations--some in full color--and lays the groundwork for using easily accessible software to immediately apply the techniques to your data. Catalog no. C410X, ISBN: 978-1-58488-410-1 December 2003, 6 x 9, 472 pp. Suggested Price: $104.95 / £66.99 Also available as an eBook

Incomplete Categorical Data Design Non-randomized Response Techniques for Sensitive Questions in Surveys Guo-Liang Tian The University of Hong Kong, People’s Republic of China

A Practical Guide Using Statistical Software Brady T. West, Kathleen B. Welch, and Andrzej T Galecki University of Michigan, Ann Arbor, USA

This easy-to-use resource provides a clear explanation of mixed modeling techniques and theories and demonstrates the use of popular statistical software procedures for fitting linear mixed models (LMMs). The authors fit LMMs based on both general and hierarchical model specifications, develop the modelbuilding process step-by-step, and demonstrate the estimation, testing, and interpretation of fixed-effect parameters and covariance parameters associated with random effects. These concepts are illustrated through examples of realworld data sets using R, SAS, SPSS, HLM, and Stata that enable comparison of model fitting options and results across the software procedures. A supporting website provides software code and the data sets discussed in the book. Catalog no. C4800, ISBN: 978-1-58488-480-4 November 2006, 7 x 10, 376 pp. Suggested Price: $99.95 / £62.99 Also available as an eBook

Textbook

Linear Models with R Julian J. Faraway University of Bath, UK Chapman & Hall/CRC Texts in Statistical Science

Man-Lai Tang Hong Kong Baptist University, People’s Republic of China

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Linear Mixed Models

Unlike the established randomized response (RR) technique, non-randomized response (NRR) techniques yield reproducible results in survey design and analysis. This book presents new techniques designed to overcome the bias inherent in posing sensitive questions in sociological or behavioral science surveys, without requiring a means of randomization. The authors provide a systematic introduction to NRR techniques that can overcome the limitations of RR techniques, combining the strengths of existing approaches, such as RR models, incomplete data design, expectation-maximization algorithm, data augmentation algorithm, and bootstrap method. Catalog no. K12579, ISBN: 978-1-4398-5533-1 February 2013, 6-1/8 x 9-1/4, 230 pp. Suggested Price: $89.95 / £57.99

In the first book that directly uses R to teach data analysis, Linear Models with R focuses on the practice of regression and analysis of variance. It clearly demonstrates the different methods available and more importantly, in which situations each one applies. It covers all of the standard topics, from the basics of estimation to missing data, factorial designs, and block designs, but it also includes discussion on topics, such as model uncertainty, rarely addressed in books of this type. The presentation incorporates an abundance of examples that clarify both the use of each technique and the conclusions one can draw from the results. All of the data sets used in the book are available for download from the Internet. Figure slides are available upon qualifying course adoption

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Catalog no. C4258, ISBN: 978-1-58488-425-5 August 2004, 6-1/8 x 9-1/4, 240 pp. Suggested Price: $91.95 / £48.99

Textbook

Textbook

Introduction to Statistical Limit Theory Alan M. Polansky Northern Illinois University, Dekalb, USA Chapman & Hall/CRC Texts in Statistical Science

Helping readers develop a good understanding of asymptotic theory, this text provides a thorough yet accessible treatment of common modes of convergence and their related tools used in statistics. The author explains as much of the background material as possible and incorporates detailed proofs and explanations of the results. The text includes many end-of-chapter exercises and experiments that range in level of difficulty from easy to advanced. Numerous examples illustrate the application of asymptotic theory to modern statistical problems. Figure slides are available upon qualifying course adoption

Catalog no. C6604, ISBN: 978-1-4200-7660-8 January 2011, 6-1/8 x 9-1/4, 645 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

Logistic Regression Models Joseph M. Hilbe California Institute of Technology, Pasadena, and Arizona State University, Tempe, USA Chapman & Hall/CRC Texts in Statistical Science

This text presents an overview of the full range of logistic models, including binary, proportional, ordered, and categorical response regression procedures. It illustrates how to apply the models to medical, health, environmental/ecological, physical, and social science data. Stata is used to develop, evaluate, and display most models while R code is given at the end of most chapters. The author examines the theoretical foundation of the models and describes how each type of model is established, interpreted, and evaluated as to its goodness of fit. Example data sets are available online in various formats and a solutions manual is available upon qualifying course adoption.

Catalog no. C7575, ISBN: 978-1-4200-7575-5 May 2009, 6-1/8 x 9-1/4, 656 pp. Suggested Price: $87.95 / £56.99 Also available as an eBook

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Longitudinal Data Analysis

Methods of Statistical Model Estimation

Edited by

Joseph M. Hilbe California Institute of Technology, Pasadena, and Arizona State University, Tempe, USA

Series: Chapman & Hall/CRC Handbooks of Modern Statistical Methods

Andrew Robinson

With contributions from some of the most prominent researchers in the field, this carefully edited collection provides a clear, comprehensive, and unified overview of recent developments in statistical methods for the analysis of longitudinal data. Focusing on both theory and applications, it addresses challenges that arise in analyzing longitudinal data, emphasizes statistical models and methods likely to endure in the future, highlights connections between various research threads in the statistical literature, and contains numerous examples and case studies drawn from a range of disciplines. Data sets, software programs, and other material are available on the editors’ website.

In many situations, standard statistical models may not be suitable for the data being studied; the researcher will need to construct a model that will provide appropriate parameter estimates. This book provides a step-by-step guide to estimating regression models using optimization, maximum likelihood, quadrature, and simulation. The text allows readers to develop their own R code for models relevant to the data they are studying. It begins with background material and basic models, building through to more complex situations, such as mixed effects models. It contains data from various disciplines, illustrating how the techniques can be applied to building models for real data problems.

Catalog no. C6587, ISBN: 978-1-58488-658-7 August 2008, 7 x 10, 632 pp. Suggested Price: $109.95 / £69.99

Catalog no. K12707, ISBN: 978-1-4398-5802-8 March 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $89.95 / £57.99

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Also available as an eBook

University of Melbourne, Parkville, Australia

Markov Chain Monte Carlo in Practice Nonparametric Statistical Tests

Edited by

W.R. Gilks Institute of Public Health, Cambridge, UK

A Computational Approach

S. Richardson

Markus Neuhauser

Imperial College, London, UK

Statistical Theory and Methods

Garrett Fitzmaurice, Marie Davidian, Geert Verbeke, and Geert Molenberghs

Koblenz University of Applied Sciences, Remagen, Germany

D.J. Spiegelhalter University of Cambridge, UK Series: Chapman & Hall/CRC Interdisciplinary Statistics

General state-space Markov chain theory has evolved to make it both more accessible and more powerful. Markov Chain Monte Carlo in Practice introduces MCMC methods and their applications while also providing some theoretical background. Considering the broad audience, the editors emphasize practice rather than theory and keep the technical content to a minimum. They offer step-by-step instructions for using the methods presented and show the importance of MCMC in real applications with examples ranging from the simple to the more complex in fields such as archaeology, astronomy, biostatistics, genetics, epidemiology, and image analysis. Catalog no. C5551, ISBN: 978-0-412-05551-5 December 1995, 6-1/8 x 9-1/4, 512 pp. Suggested Price: $125.95 / £79.99

This book provides a modern and accessible overview of computationally intensive nonparametric statistical methods. Presenting up-to-date and detailed information, the text focuses on the use of permutation and bootstrap methods to assess the significance of a statistic in a hypothesis test. It includes numerous real examples to illustrate the methods, and SAS programs are used throughout to apply them. In addition, a significant portion of the book is devoted to (recent) nonparametric tests for the comparison of independent groups with potentially unequal variances. Catalog no. K13006, ISBN: 978-1-4398-6703-7 December 2011, 6-1/8 x 9-1/4, 248 pp. Suggested Price: $93.95 / £59.99 Also available as an eBook

SAS and R Mendelian Randomization

Data Management, Statistical Analysis, and Graphics Ken Kleinman

Statistical Methods for Using Genes to Estimate Causal Associations

Harvard Medical School, Boston, Massachusetts, USA

Stephen Burgess and Simon G. Thompson Mendelian randomization is a way of assessing causal associations from observational data, which is especially important for medical scientists and epidemiologists who want to know the true causes of diseases. Covering this emerging area of research in biostatistics and epidemiology, this book examines the use of genetic variants as instrumental variables to assess causal associations. It also discusses statistical issues with instrumental variable analysis and explores practical applications of Mendelian randomization. The methods are illustrated with a variety of detailed worked examples using real data.

Eliminating the need to consult laborious documentation, this book presents an easy way to learn how to perform an analytical task in both SAS and R. It covers many common tasks, along with more complex applications. The text provides parallel examples in SAS and R to demonstrate how to use the software and derive identical answers regardless of software choice. It also gives insight into the process of statistical coding from beginning to end by supplying worked examples of complex coding tasks. The authors include an index for each software, allowing users to easily locate procedures. They offer the SAS and R data sets and code for download online.

Catalog no. K16638, ISBN: 978-1-4665-7317-8 June 2013, 6-1/8 x 9-1/4, 200 pp. Suggested Price: $59.95 / £34.99

Catalog no. C7057, ISBN: 978-1-4200-7057-6 July 2009, 7 x 10, 343 pp. Suggested Price: $79.95 / £49.99

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Also available as an eBook

Nicholas. J Horton Smith College, Northampton, Massachusetts, USA

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Textbook

Statistical Computing with R

Theory of Factorial Design

Maria L. Rizzo

University of California, Berkeley, USA

Bowling Green State University, Ohio, USA Chapman & Hall/CRC The R Series

Statistical Theory and Methods

This text covers the traditional core material of computational statistics, with an emphasis on using the R language via an examples-based approach. An excellent tutorial on R programming techniques used in practical computational problems, it illustrates every algorithm with at least one fully implemented example coded in R. The book also offers the source code for all examples online and contains numerous exercises. Key topics covered include the simulation of random variables from probability distributions, the visualization of multivariate data, Monte Carlo integration and variance reduction methods, Monte Carlo methods in inference, bootstrap and jackknife, MCMC methods, and density estimation. A solutions manual is available upon qualifying course adoption

Catalog no. C5459, ISBN: 978-1-58488-545-0 November 2007, 6-1/8 x 9-1/4, 416 pp. Suggested Price: $97.95 / £43.99

Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability

This self-contained book provides a rigorous, systematic, and up-to-date treatment of the modem theory of factorial design. It includes lots of examples, predominantly from engineering and agriculture, to illustrate the methods. The book incorporates a few exercises in each chapter to enable the book to be used for self-study or for a special topics course. Topics covered include a general theory of multi-stratum factorial design, design key for constructing factorial designs, new construction methods of resolution IV designs, and some results on their structures taken from the literature of projective geometry. Catalog no. K14573, ISBN: 978-1-4665-0557-5 June 2013, 6-1/8 x 9-1/4, 416 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Textbook

Statistical Inference An Integrated Approach, Second Edition

Time Series Modeling of Neuroscience Data

Helio S. Migon, Dani Gamerman, and Francisco Louzada-Neto

Tohru Ozaki Institute of Statistical Mathematics, Tokyo, Japan

Chapman & Hall/CRC Texts in Statistical Science

Series: Chapman & Hall/CRC Interdisciplinary Statistics

Unique in its presentation of topics from both classical and Bayesian perspectives, this second edition balances both sides elegantly and describes the relative strengths and weaknesses of the different approaches in each case. It covers all the key topics of standard inference courses, including point and interval estimation, hypothesis testing, prediction, approximation, and linear models. Along with real data examples and exercises for self-study, this edition offers numerous updates that reflect recent developments.

Due to recent advances in methodology that offer significant improvements over conventional methods, there is increasing interest in the use of time series models for the study of neuroscience data such as EEG, MEG, fMRI, and NIRS. This book presents an overview of time series models for the study of neuroscience data. Accessible to applied statisticians as well as quantitatively trained neuroscientists, the book is supported by many real examples to illustrate the methods and provides useful instructions for computational problems, enabling readers to develop their own computational toolbox to apply the methods to real data.

Figure slides are available upon qualifying course adoption

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Ching-Shui Cheng

Catalog no. K13686, ISBN: 978-1-4398-7880-4 June 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $89.95 / £57.99

Catalog no. C4602, ISBN: 978-1-4200-9460-2 January 2012, 6-1/8 x 9-1/4, 574 pp. Suggested Price: $99.95 / £63.99 Also available as an eBook

Textbook

Statistical Methods for Handling Missing Data Jae Kwang Kim Jun Shao Chapman & Hall/CRC Texts in Statistical Science

With advances in computing power, there have been substantial developments in computational methods for handling missing data. This text presents an introduction to the theory, applications, and computational aspects of missing data analysis. It covers the three main methodological approaches: likelihoodbased, nonparametric, and quasi-randomization. The text includes many real examples and integrates computer code where appropriate. It also provides exercises at the end of each chapter. A solutions manual is available upon qualifying course adoption

Catalog no. K12249, ISBN: 978-1-4398-4963-7 June 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $89.95 / £57.99 Also available as an eBook

Using R for Data Management, Statistical Analysis, and Graphics Nicholas J. Horton Smith College, Northampton, Massachusetts, USA

Ken Kleinman Harvard Medical School, Boston, Massachusetts, USA

This book presents an easy way to learn how to perform an analytical task in R, without having to navigate through its extensive, idiosyncratic, and sometimes unwieldy software documentation and vast number of add-on packages. Showing how to efficiently use the powerful R system, the authors cover data management, descriptive summaries, inferential procedures, regression analysis, multivariate methods, and the creation of graphics. The text includes convenient indices organized by topic and R syntax and contains many example analyses. Data sets and code are available for download on the book’s website. Catalog no. K11360, ISBN: 978-1-4398-2755-0 July 2010, 6-1/8 x 9-1/4, 297 pp., Soft Cover Suggested Price: $65.95 / £41.99 Also available as an eBook

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CRC Handbook of Chemistry and Physics 93rd Edition Edited by

Textbook

Technical Writing A Practical Guide for Engineers and Scientists Phillip A. Laplante

National Institute of Standards and Technology, Boulder, Colorado, USA

The Pennsylvania State University, Malvern, USA

Mirroring the growth and direction of science for a century, the handbook, now in its 93rd edition, continues to be the most accessed and respected scientific reference in the world. An authoritative resource consisting tables of data, its usefulness spans every discipline. This edition includes 17 new tables in the Analytical Chemistry section, a major update of the CODATA Recommended Values of the Fundamental Physical Constants and updates to many other tables. The book puts physical formulas and mathematical tables used in labs every day within easy reach. The 93rd edition is the first edition to be available as an eBook.

Written by a renowned engineer and widely published technical author, this guide enables readers to write, edit, and publish materials of a technical nature, including books, articles, reports, and electronic media. Complementing the traditional writer’s reference manuals and other books on technical writing, it helps readers understand the practical considerations in writing technical content. Drawing on his own work, the author presents many first-hand examples of writing, editing, and publishing technical materials. These examples illustrate how a publication originated as well as various challenges and solutions.

An instructor’s manual is available upon qualifying course adoption

Catalog no. K11106, ISBN: 978-1-4398-2085-8 July 2011, 6-1/8 x 9-1/4, 250 pp., Soft Cover Suggested Price: $41.95 / £26.99

Catalog no. K13784, ISBN: 978-1-4398-8049-4 June 2012, 8-1/2 x 11, 2664 pp. Suggested Price: $169.95 / £108.00

Series: What Every Engineer Should Know

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Textbook

Entrepreneurship in Chemistry and the Life Sciences Cedric Pearce

Understanding Nanomedicine

General References

William M. Haynes

An Introductory Textbook Rob Burgess

Science entrepreneurship has unique aspects when compared to many other businesses. Research scientists are fortunate because they are exposed to new ideas and breakthroughs before anyone else, and since they are usually the first to develop new technologies, they have the potential of being first to market. However, scientists typically are not trained to think of discoveries as potential business opportunities and many are lost even though they might have a significant impact on society. This book is designed to help chemistry and life scientists start their own businesses. For graduates, this book provides a background of new companies and how they operate. Full of examples, it is an excellent introduction to the process of successfully identifying new scientific discoveries with commercial potential and establishing businesses based on new technology. Catalog no. K15334, ISBN: 978-1-4665-5476-4 June 2013, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $39.95 / £25.99

Medical Nanotechnologies Incorporated, Richardson, Texas, USA

This book comprehensively covers a broad range of therapeutic and diagnostic applications of nanotechnology, providing descriptions of cutting-edge discoveries along with historical perspectives. The text focuses on nanomaterials and nanoparticles, the sectors that hold the most promise for the future of medicine. The author looks at how nanotechnology can impact cancer treatment, clinical neuroscience, tissue engineering, drug delivery, and diagnostics. He also discusses the worldwide governmental regulatory impact on nanomedicine. Catalog no. N10477, ISBN: 978-981-4316-38-5 June 2012, 6 x 9, 524 pp. Suggested Price: $149.95 / £95.00 Also available as an eBook

Also available as an eBook

Nobel Laureates The Art and Science of Chemistry in Biomedical Research Volume 1 Vassil St. Georgiev National Institutes of Health, Bethesda, Maryland, USA

Providing detailed summaries, this reference reviews the biomedical research conducted over the last 110 years for which most of the Nobel Prizes in Chemistry have been awarded. It encompasses not only the initial discoveries made in each particular field of science that were honored with a Nobel Prize but also the contributions of countless other scientists before and after the prize was given that greatly expanded the field to the present day. Presented in full color throughout, the text also presents historical and socioeconomic context associated with the Nobel Prizes, including brief remarks on historical events. Catalog no. K14401, ISBN: 978-1-4665-0173-7 January 2013, 8-1/2 x 11, 1944 pp. Suggested Price: $349.95 / £223.00 Also available as an eBook

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91


A A Handbook of Statistical Analyses Using R, Second Edition....84 Adaptive and Flexible Clinical Trials........................................59 Adaptive Design Methods in Clinical Trials, Second Edition....60

Biomedical Technology and Devices, Second Edition..............17 BioMEMS: Science and Engineering Perspectives....................17

B

Adaptive Motion Compensation in Radiotherapy...................70

Bacterial NanoCellulose: A Sophisticated Multifunctional Material....................................................................................9

Adaptive Optics for Biological Imaging...................................30

Basic Pharmacokinetics, Second Edition..................................64

Advanced Bayesian Methods for Medical Test Accuracy..........70

Bayesian Adaptive Methods for Clinical Trials..........................72

Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery.............................................14

Bayesian Analysis Made Simple: An Excel GUI for WinBUGS...72

Advanced Biophotonics: Tissue Optical Sectioning.................14 Advanced Drug Delivery Nanoparticles..................................61 Advanced Materials for Joint Implants....................................14

Bayesian Disease Mapping: Hierarchical Modeling in Spatial Epidemiology, Second Edition.....................................72 Bayesian Ideas and Data Analysis: An Introduction for Scientists and Statisticians.......................................................85

Title Index

Advanced Practical Organic Chemistry, Third Edition...............3

Bayesian Inference for Partially Identified Models: Exploring the Limits of Limited Data.......................................85

Advanced Risk Analysis in Engineering Enterprise Systems......83

Bayesian Methods for Data Analysis, Third Edition..................85

Advances in Chromatography, Volume 49..............................37

Bayesian Methods in Health Economics..................................72

Advances in Chromatography, Volume 50..............................38

Bayesian Methods: A Social and Behavioral Sciences Approach, Second Edition......................................................84

Advances in Chromatography, Volume 51..............................38 Advances in Cognitive Engineering and Neuroergonomics.....53 Advances in Natural Medicines, Nutraceuticals and Neurocognition......................................................................61 Advances in Russian and International Neurotechnology........53 Advances in Therapeutic Engineering.....................................14 Age-Period-Cohort Analysis: New Models, Methods, and Empirical Applications............................................................70 Alzheimer’s Disease: Targets for New Clinical Diagnostic and Therapeutic Strategies ...........................................................54 Ambient Assisted Living..........................................................14 Amino Acid Chelation in Human and Animal Nutrition............3 Amino Acids: Biochemistry and Nutrition.................................3 An Introduction to Bayesian Biostatistics.................................76

Bayesian Methods: A Social and Behavioral Sciences Approach, Third Edition..........................................................84 Bayesian Phylogenetics: Methods, Computational Algorithms, and Applications..................................................68 Benefit Risk Analysis in Pharmaceutical Research and Development.........................................................................72

Analytical Chemistry for Technicians, Fourth Edition...............38 Applications of Proteomics to Cell Signaling...........................45 Applications of Supramolecular Chemistry................................3 Applied Categorical and Count Data Analysis.........................85 Applied Medical Image Processing: A Basic Course.................71

Biopharmaceutical Supply Chains: Distribution, Regulatory, Systems and Structural Changes Ahead..................................63 Biophysics for Beginners: A Journey through the Cell Nucleus...........................................................................46 Biosensors and Environmental Health.....................................10 Biosensors and Molecular Technologies for Cancer Diagnostics.............................................................................18 Biosensors Based on Nanomaterials and Nanodevices............18 Biosensors: Theory and Applications.......................................10 Bioseparation Technology.......................................................32 Biosignal Processing: Principles and Practices..........................19 Biostatistics: A Computing Approach......................................72 Biotechnological Applications of Microalgae: Biodiesel and Value Added Products.............................................................33 Biotechnology Fundamentals.................................................33

Biotechnology Operations: Principles and Practices................33

Biodefense Research Methodology and Animal Models, Second Edition.......................................................................47

Biolgical and Biomedical Coatings Handbook...........................9

Biotechnology of Plasma Proteins.............................................4

Boron Science: New Technologies and Applications...............33

C Cadmium Telluride Quantum Dots: Advances and Applications.....................................................42

Biological and Biomedical Coatings Handbook: Applications....9

Cancer Nanotechnology: Principles and Applications in Radiation Oncology................................................................42

Biological and Biomedical Coatings Handbook: Processing and Characterization...............................................9

Carbohydrate Chemistry: Proven Synthetic Methods, Volume 1..................................................................................4

Biological and Medical Sensor Technologies...........................41 Biological Computation..........................................................81

Carbohydrate Chemistry: Proven Synthetic Methods, Volume 2..................................................................................4

Biologically Inspired Robotics..................................................13

Carbohydrate-Modifying Biocatalysts.......................................4

Biomaterials and Stem Cells in Regenerative Medicine..............9

Carbon Nanotubes: From Bench Chemistry to Promising Biomedical Applications..........................................................10

Biomaterials for MEMS.............................................................9 Biomaterials for Stem Cell Therapy: State of Art and Vision for the Future...............................................................42

Applied Medical Statistics Using SAS.......................................71 Applied Nonparametric Statistical Methods, Fourth Edition....85

Biomaterials: Principles and Practices......................................10

Applied Optics Fundamentals and Device Applications: Nano, MOEMS, and Biotechnology........................................32

Biomechanics of Human Motion: Applications in the Martial Arts.............................................................................16

Applied Survey Data Analysis..................................................71

Biomechanics of the Upper Limbs: Mechanics, Modeling and Musculoskeletal Injuries, Second Edition.................................13 Biomechanics: Principles and Practices...................................16

Articular Cartilage...................................................................15

Biomechatronics in Medicine and Healthcare.........................16

Artificial Human Sensors: Science and Applications.................71

Biomedical Applications of Mesoporous Ceramics: Drug Delivery, Smart Materials and Bone Tissue Engineering...........16

Artificial Neural Networks in Biological and Environmental Analysis..................................................................................38

Bionanotechnology II: Global Prospects..................................18

Biochemical Sensors: Mimicking Gustatory and Olfactory Senses....................................................................................15

Biomaterials Science: An Integrated Clinical and Engineering Approach.................................................................................3

Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition..............................................59

Bionanomaterials for Dental Applications...............................10 Bionanotechnology................................................................18

Biotechnology of Fungal Genes..............................................33

Biological and Bioenvironmental Heat and Mass Transfer.......16

Analysis of Questionnaire Data with R.....................................71

Biomimicry: Architecture and Design......................................46

Bioactive Natural Products: Detection, Isolation, and Structural Determination, Second Edition.................................3

Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation, Second Edition..........................15

Analysis of Mixed Data...........................................................85

Biomimetics: Nature-Based Innovation...................................18

Biotechnology in Agriculture and Food Processing: Opportunities and Challenges................................................33

Biofluid Mechanics: The Human Circulation, Second Edition..15

Analysis of Messy Data Volume 1: Designed Experiments, Second Edition.......................................................................84

Biomimetics and Ocean Organisms: An Engineering Design Perspective.................................................................18

Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery.......65

An Introduction to Generalized Linear Models, Third Edition...........................................................................84

Analysis of Capture-Recapture Data........................................83

92

Augmenting Cognition...........................................................54 A-Z of Error-Free Research......................................................71

Causal Inference.....................................................................73 Cell Culture Technology for Pharmaceutical and Cell-Based Therapies................................................................................59 Cellular Potts Models: Mutiscale Extensions and Biological Applications............................................................................81 Chemical Components of Tobacco and Tobacco Smoke, Second Edition.......................................................................58 Chemical Genomics and Proteomics, Second Edition...............4 Chemical Modification of Biological Polymers........................52 Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds............................................................65 Chemistry Companion.............................................................4 Chemistry of Heterocyclic Compounds.....................................5

Biomedical Engineering Handbook, Fourth Edition: Four Volume Set.....................................................................13

Chemistry of Natural Products: A Laboratory Handbook.........65

Biomedical Engineering Principles, Second Edition.................16

Chirality in Biological Nanospaces: Reactions in Active Sites.....5

Assistive Technology Assessment Handbook...........................15

Biomedical Photonics Handbook, Second Edition...................17

Chitosan-Based Hydrogels: Functions and Applications............5

Assistive Technology for Blindness and Low Vision..................15

Biomedical Photonics Handbook, Second Edition: Therapeutic and Advanced Biophotonics................................17

Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions..............................53

Biomedical Sensors and Instruments, Second Edition.............17

Clinical Nanomedicine Handbook..........................................19

Biomedical Signal and Image Processing, Second Edition.......30

Clinical Trial Data Analysis Using R..........................................73

Asbestos: Risk Assessment, Epidemiology, and Health Effects, Second Edition................................................58

Astrocytes: Wiring the Brain....................................................54 Atlas of Fish Histology.............................................................47 Atlas of the Neonatal Rat Brain...............................................54

Chemotherapy-Induced Neuropathic Pain..............................54

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Coherent Raman Scattering Microscopy.................................73 Colloids and Interfaces in Life Sciences and Bionanotechnology, Second Edition.......................................34 Comprehensive Brachytherapy: Physical and Clinical Aspects.......................................................................31 Computational and Visualization Techniques for Structural Bioinformatics using Chimera.................................................68 Computational Neuroscience: Simulated Demyelinating Neuropathies and Neuronopathies.........................................54

H

Dynamics of the Chemostat: A Bifurcation Theory Approach...............................................................................82

E Electroanalysis with Carbon Paste Electrodes..........................34 Electrokinetic Particle Transport in Micro-/Nanofluidics: Direct Numerical Simulation Analysis......................................38

Handbook of Active Materials for Medical Devices: Advances and Applications.....................................................10 Handbook of Analysis of Oligonucleotides and Related Products.....................................................................35 Handbook of Analytical Validation..........................................39

Electromagnetic Fields in Biological Systems...........................20

Handbook of Applied Statistics in Pharmacology....................83

Emergent Patterns and the Brain..............................................5

Handbook of Aqueous Solubility Data, Second Edition.............6

Emerging Imaging Technologies in Medicine.........................74

Handbook of Biochemistry and Molecular Biology, Fourth Edition...........................................................................6

Encyclopaedia of Medical Physics...........................................20

Handbook of Biofunctional Surfaces.......................................35

Computational Systems Biology of Cancer.............................69

Encyclopedia of Biotechnology in Agriculture and Food (Print Version).........................................................................34

Computer Access for People with Disabilities: A Human Factors Approach....................................................19

Encyclopedia of Chromatography, Third Edition.....................39

Handbook of Dynein..............................................................46

Engineering Aspects of Food Biotechnology...........................34

Handbook of Forensic Toxicology for Medical Examiners........58

Engineering of Polysaccharide Materials: by PhosphorylaseCatalyzed Enzymatic Chain-Elongation.....................................8

Handbook of Harnessing Biomaterials in Nanomedicine: Preparation, Toxicity, and Applications...................................11

Entrepreneurship in Chemistry and the Life Sciences..............91

Handbook of Intelligent Scaffold for Tissue Engineering and Regenerative Medicine...........................................................21

Computer Vision: From Surfaces to 3D Objects......................19 Concussive Brain Trauma: Neurobehavioral Impairment & Maladaptation, Second Edition...............................................55 Consumers and Nanotechnology: Deliberative Processes, Social Barriers and Methodologies..........................................42 Controversial Statistical Issues in Clinical Trials........................60

Epidemiology: Study Design and Data Analysis, Second Edition.......................................................................74

Correction Techniques in Emission Tomography.....................31

Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics..................................55

CRC Handbook of Chemistry and Physics, 93rd Edition..........91

Essentials of Functional MRI....................................................74

CRC Handbook of Organic Photochemistry and Photobiology, Third Edition - Two Volume Set................................................5

Essentials of Law and Ethics for Pharmacy Technicians, Third Edition...........................................................................67

CRC World Dictionary of Medicinal and Poisonous Plants: Common Names, Scientific Names, Eponyms, Synonyms, and Etymology (5 Volume Set)...............................................58

Event History Analysis with R..................................................74

Current Pharmacy Review.......................................................67

Extending the Linear Model with R: Generalized Linear, Mixed Effects and Nonparametric Regression Models.............86

Current Research in Animal Physiology...................................49 Current Research in Pharmaceutical Technology.....................65 Cytokines...............................................................................46

D Data Mining for Bioinformatics...............................................69 Data Mining in Biomedical Imaging, Signaling, and Systems...........................................................................81 Dermatokinetics of Therapeutic Agents..................................65 Design and Analysis of Bridging Studies.................................60 Design and Analysis of Experiments with SAS.........................86 Design Controls for the Medical Device Industry....................19 Design of Biomedical Devices and Systems, Second Edition...19 Development of Medical Garments and Apparel for the Elderly and the Disabled................................................5 Diagnostic Endoscopy............................................................20 Dictionary of Alkaloids, Second Edition with CD-ROM............65 Dictionary of Marine Natural Products with CD-ROM.............61 Differential Equations and Mathematical Biology, Second Edition.......................................................................81 Disposable Bioprocessing Systems..........................................64 DNA Liquid-Crystalline Dispersions and Nanoconstructions....42 DNA Nanotechnology............................................................42

Exploratory Multivariate Analysis by Example Using R.............86

F

Handbook of Lipid Bilayers, Second Edition..............................6 Handbook of Markov Chain Monte Carlo...............................87 Handbook of Microbiological Media, Fourth Edition...............51 Handbook of Near-Infrared Analysis, Third Edition..................39 Handbook of Parametric and Nonparametric Statistical Procedures, Fifth Edition.........................................................87

Handbook of Spatial Statistics.................................................87

Flavonoids and Related Compounds: Bioavailability and Function.................................................................................66

Handbook of Statistical Analyses Using Stata, Fourth Edition..75

Flexible Imputation of Missing Data.......................................86 Flexible Parametric Survival Analysis Using Stata: Beyond the Cox Model...........................................................74 Fluctuation Theory of Solutions: Applications in Chemistry, Chemical Engineering, and Biophysics......................................6 Fluorescent Protein Revolution...............................................81

Handbook of Statistical Analyses using SAS, Third Edition.......75

Handbook of Statistics in Clinical Oncology, Third Edition......75 Handbook of Therapeutic Biomarkers in Cancer.....................46 Hansen Solubility Parameters: A User’s Handbook, Second Edition.........................................................................6 Hazardous Drugs in Healthcare, Pharmaceutical and Veterinary Facilities: Strategies in Achieving Compliance.........................68

Forensic Toxicology: Medico-Legal Case Studies.....................58

Healthcare Sensor Networks: Challenges Toward Practical Implementation......................................................................21

From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection.................................................20

Heart Rate Variability (HRV) Signal Analysis: Clinical Applications...............................................................21

From MEMS to Bio-MEMS and Bio-NEMS: Manufacturing Techniques and Applications..................................................20

Hidden Markov Models for Time Series: An Introduction Using R.........................................................87

Functional Fold: Amyloid Structures in Nature........................53

Hierarchical Modeling and Analysis for Spatial Data................88

Fundamental QSARs for Metal Ions...........................................6

Human Error in Medicine, Second Edition..............................62

Fundamentals of Biomechanics..............................................21

Human Eye Imaging and Modeling........................................75

Fundamentals of Nanotechnology..........................................43

G Gaussian Process Regression Analysis for Functional Data.......86

Drug Delivery and Targeting: For Pharmacists and Pharmaceutical Scientists........................................................67

Gene Biotechnology, Third Edition.........................................34

Dynamic Force Spectroscopy and Biomolecular Recognition............................................................................38

Handbook of Laboratory Animal Science, Volume III: Animal Models, Third Edition.............................................................49

Handbook of SAS® DATA Step Programming..........................74

Dose Finding by the Continual Reassessment Method............73

Drugs of Natural Origin: A Treatise of Pharmacognosy, Sixth Revised Edition..............................................................61

Handbook of Laboratory Animal Science, Volume II, Third Edition: Animal Models.................................................49

Feedback Control in Systems Biology.....................................20

Game-Theoretical Models in Biology......................................82

Drug Delivery Systems, Third Edition......................................66

Handbook of Laboratory Animal Science, Volume I, Third Edition: Essential Principles and Practices.......................49

Fermentation Microbiology and Biotechnology, Third Edition...........................................................................51

Dopamine – Glutamate Interactions in the Basal Ganglia........55

Drug Delivery Systems for Cardiovascular Diseases.................61

Handbook of Biomedical Optics.............................................21

Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications...........................................................62 Hydroxyapatite Coatings for Biomedical Applications.............11 Hyphenated and Alternative Methods of Detection in Chromatography....................................................................39

I

Generalized Additive Models: An Introduction with R.............86 Generalized Estimating Equations, Second Edition..................87 Generalized Latent Variable Modeling: Multilevel, Longitudinal, and Structural Equation Models........................87

IACUC Handbook, Second Edition..........................................49 Ibuprofen: A Critical Bibliographic Review, 2nd Edition...........66 Image Analysis and Modeling in Opthalmology.....................75

Genetic Engineering: Recent Developments in Applications...21

Image Processing in Radiation Therapy...................................31

Genetics, Genomics, and Breeding of Bananas.......................35

Image Processing: Tensor Transform and Discrete Tomography with MATLAB®...................................................22

Dynamic Prediction in Clinical Survival Analysis......................73

Genome Annotation...............................................................69

Dynamical Models in Medicine...............................................82

Green Tea Polyphenols: Nutraceuticals of Modern Life...........61

Title Index

Cluster Randomised Trials.......................................................73 CMOS Nanoelectronics: Innovative Devices, Architectures, and Applications...............................................34

Incomplete Categorical Data Design: Non-randomized Response Techniques for Sensitive Questions in Surveys.........88

Dynamics of Biological Systems..............................................82

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93


Infectious Diseases and Pathology of Reptiles: Color Atlas and Text........................................................................................50 Inflammation, Lifestyle and Chronic Diseases: The Silent Link........................................................................46 Informatics in Medical Imaging..............................................75 Instrumental Data for Drug Analysis, Third Edition 6 Volume Set..........................................................................58 Integrated Microsystems: Electronics, Photonics, and Biotechnology........................................................................35 Interval-Censored Time-to-Event Data: Methods and Applications............................................................................76

Laboratory Swine, Second Edition..........................................48 Laboratory Xenopus sp...........................................................49

Modeling and Control for Micro/Nano Devices and Systems...........................................................................43 Modelling and Quantitative Methods in Fisheries, Second Edition.......................................................................83

Laboratory Zebrafish..............................................................49

Modelling Survival Data in Medical Research, Second Edition.......................................................................77

Lactic Acid Bacteria: Microbiological and Functional Aspects, Fourth Edition.........................................................................36

Molecular Detection of Human Bacterial Pathogens...............52

Law of Regenerative Medicine and Tissue Engineering...........22 LC-NMR: Expanding the Limits of Structure Elucidation.........40

Molecular Detection of Human Fungal Pathogens..................52 Molecular Motors in Bionanotechnology................................36

Title Index

Learning Bio-Micro-Nanotechnology......................................23

Monte Carlo Calculations in Nuclear Medicine, Second Edition: Applications in Diagnostic Imaging...............31

Introduction to Biomaterials, Second Edition............................7

Leonard; John...........................................................................3

Monte Carlo Techniques in Radiation Therapy........................31

Introduction to Biomedical Engineering Technology, Second Edition.......................................................................22

Life at the Nanoscale: Atomic Force Microscopy of Live Cells................................................................................43

MRI: Essentials for Innovative Technologies.............................77

Introduction to Bio-Ontologies...............................................69

Linear and Chiral Dichroism in the Electron Microscope.........40

Introduction to Experimental Biophysics: Biological Methods for Physical Scientists...............................39

Linear Mixed Models: A Practical Guide Using Statistical Software.................................................................................88

Introduction to GC-MS Spectrometry.....................................39

Linear Models with R..............................................................88

Introduction to Instrumentation in Life Sciences.....................35

Logistic Regression Models.....................................................88

Introduction to Lipidomics: From Bacteria to Man....................7

Longitudinal Data Analysis......................................................89

Introduction to Medical Imaging Management......................76

Lung Imaging and Computer Aided Diagnosis.......................77

Introduction to Nanoscience..................................................43

Lygo; Barry...............................................................................3

Introduction to Nanoscience and Nanotechnology................43 Introduction to Natural Products Chemistry...........................66 Introduction to Nutrition and Metabolism, Fourth Edition........7

M Making and Using Antibodies: A Practical Handbook, Second Edition.......................................................................62

Introduction to Physics in Modern Medicine, Second Edition.......................................................................22

Manipulative Tenants: Bacteria Associated with Arthropods....51

Introduction to Proteins: Structure, Function, and Motion........7

Marine Biomaterials: Characterization, Isolation and Applications............................................................................11

Introduction to Stata for Health Researchers, Third Edition.....76 Introduction to Statistical Data Analysis for the Life Sciences...........................................................................83

Marine Pharmacognosy: Trends and Applications...................66 Markov Chain Monte Carlo in Practice...................................89

Introduction to Statistical Limit Theory...................................88

Mass Transport of Nanocarriers..............................................23

Introduction to Statistical Methods for Clinical Trials...............76

Materials Science of DNA.......................................................11

Introduction to Statistics and Data Analysis for Bioinformatics using R............................................................69

Math Unlimited: Essays in Mathematics..................................83

Introduction to Stochastic Processes with Applications to Biology, Second Edition..........................................................82

Mechanics of Cellular Bone Remodeling: Coupled Thermal, Electrical, and Mechanical Field Effects...................................23

Introduction to Systems Biology: Design Principles of Biological Circuits...................................................................82

Mechanobiology Handbook...................................................24

Ion Mobility Spectrometry, Third Edition................................40

94

Laboratory Rat, Second Edition...............................................48 Laboratory Small Ruminant....................................................48

ISO 13485: A Complete Guide to Quality Management in the Medical Device Industry...............................................11

J, K Joint Models for Longitudinal and Time-to-Event Data: With Applications in R............................................................76 Knowledge-Driven Medicine: A Machine Learning Approach...............................................................................22

L Laboratory Animal Pocket Reference Series: 13-Volume Set....48 Laboratory Biosecurity Handbook...........................................51 Laboratory Canine..................................................................48 Laboratory Cat.......................................................................48

Measurement, Instrumentation and Sensors Handbook..........23

Medical Biostatistics, Third Edition..........................................77 Medical Device R&D Handbook, Second Edition....................24 Medical Equipment Management..........................................24 Medical Imaging: Principles and Practices..............................77 Medical Infrared Imaging: Principles and Practices.................77 Medical Instruments and Devices: Principles and Practices.....24 Medical Nanotechnology and Nanomedicine.........................24 MEMS: Packaging and Technology.........................................24 Mendelian Randomization: Statistical Methods for Using Genes to Estimate Causal Associations..........................89

Multi-Detector CT Imaging Handbook...................................78 Multifunctional Molecular Materials........................................35 Multiobjective Optimization Methodology: A Jumping Gene Approach.....................................................69 Multiple Comparisons Using R................................................60 Multiple Testing Problems in Pharmaceutical Statistics............78 Multiporphyrin Arrays: Fundamentals and Applications..........11 Multivariate Statistical Methods: A Primer, Third Edition.........84 Multivariate Survival Analysis and Competing Risks................78

N Nanoantenna: Plasmon-Enhanced Spectroscopies for Biotechnological Applications.................................................43 Nanobiomaterials Handbook..................................................25 Nanobiotechnology Handbook..............................................25 Nanobrain: Making an Intelligent Molecular Machine............44 Nanocomposite Particles for Bio-Applications: Materials and Bio-Interfaces..........................................................................25 Nanoelectronics: Devices, Circuits, and Systems.....................44 Nanofabrication Handbook....................................................12 Nanoimaging.........................................................................78 Nanomaterials for Electrochemical Sensing and Biosensing....25 Nanomedicine and Cancer Therapies.....................................44 Nanomedicine and Drug Delivery..........................................44 Nanomedicine in Drug Delivery.............................................25 Nanomedicine: A Soft Matter Perspective...............................26 Nanomedicine: Principles and Practices..................................26 Nanoneurosurgery.................................................................55 Nanostructures and Nanoconstructions based on DNA..........44 Nanotechnology: The Whole Story.........................................44 Neural Bases of Multisensory Processes...................................57 Neurobiological Basis of Suicide.............................................55 Neurobiology of Depression...................................................56 Neurobiology of Sensation and Reward..................................56

Methods for Studying Nucleic Acid/Drug Interactions............36

Neuromorphic Olfaction........................................................56

Methods of Statistical Model Estimation.................................89

Neurons and the DHA Principle..............................................56

Micro and Nano Techniques for the Handling of Biological Samples..................................................................................36

Neuropeptides in Neuroprotection and Neuroregeneration...62 Neurotechnology: Premises, Potential, and Problems.............56

Microbial Detection and Identification by Mass Spectrometry.................................................................40

Neuroviral Infections: General Principles and DNA Viruses......45

Laboratory Guinea Pig, Second Edition...................................48

Microbial Limit and Bioburden Tests: Validation Approaches and Global Requirements,Second Edition...............................52

Neuroviral Infections: Two Volume Set...................................45

Laboratory Hamster and Gerbil...............................................48

Microfabricated Cortical Neuroprostheses..............................55

Laboratory Manual in Biophotonics........................................13

Microfluidics and Nanofluidics Handbook: Chemistry, Physics, and Life Science Principles........................43

Laboratory Course in Tissue Engineering................................22 Laboratory Ferret....................................................................48

Laboratory Mouse, Second Edition.........................................48 Laboratory Nonhuman Primate..............................................48

Microspheres and Microcapsules in Biotechnology: Design, Preparation and Applications.....................................36

Laboratory Protocols in Applied Life Sciences.........................40

Microsurgery: Advances, Simulations and Applications...........25

Laboratory Protocols in Applied Life Sciences.........................40

Mitochondrial Signaling in Health and Disease.......................47

Laboratory Rabbit, Second Edition..........................................48

Neuroviral Infections: RNA Viruses and Retroviruses................45

Nobel Laureates: The Art and Science of Chemistry in Biomedical Research Volume 1...............................................91 Nonparametric Statistical Tests: A Computational Approach...............................................................................89 Numerical Methods for Chemical Engineers Using Excel, VBA, and MATLAB...............................................26 Nutritional Genomics: The Impact of Dietary Regulation of Gene Function on Human Disease..........................................53

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Q

Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging..............................................................47

Obstructive Airway Diseases: Role of Lipid Mediators..............62

Quality and Safety in Radiotherapy.........................................28

Stem Cells and Revascularization Therapies............................37

Occupational Physiology........................................................26

Quality Control Training Manual: Comprehensive Training Guide for API, Finished Pharmaceutical and Biotechnologies Laboratories............................................................................28

Stereotactic Radiosurgery and Radiotherapy...........................32

Ocular Drug Delivery Systems: Barriers and Application of Nanoparticulate Systems........................................................62 OMICs Technologies: Tools for Food Science..........................63 OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences..........................................................36 OMICS: Biomedical Perspectives and Applications..................37 Optical Imaging Techniques in Cell Biology, Second Edition.......................................................................79 Optical Techniques in Regenerative Medicine.........................26 Optimal Design for Nonlinear Response Models.....................79 Organic Chemistry: An Acid—Base Approach...........................7 Organic Chemist’s Desk Reference, Second Edition..................7 Orthopaedic Biomechanics.....................................................26

Quality Operations Procedures for Pharmaceutical, API, and Biotechnology........................................................................59 Quantifying Morphology and Physiology of the Human Body Using MRI...............................................................................32 Quantitative Biology: From Molecular to Cellular Systems......70 Quantitative Pharmacology: An Introduction to Integrative Pharmacokinetic-Pharmacodynamic Analysis..........................64 Quantitative Proteome Analysis: Methods and Applications....41 Quantitative Understanding of Biosystems: An Introduction to Biophysics.................................................28

R Randomized Clinical Trials of Nonpharmacological Treatments.............................................................................60

P

Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix jacchus).................................50 Stochastic Modelling for Systems Biology, Second Edition......70 Structural Glycobiology............................................................8 Support Vector Machines and Their Application in Chemistry and Biotechnology.................................................................37 Suturing Principles in Laboratory Animal Surgery...................50 Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition...............................51 Szycher’s Handbook of Polyurethanes, Second Edition...........29

T Targeted Molecular Imaging...................................................32 Targeted Muscle Reinnervation...............................................29

Parkinson’s Disease, Second Edition........................................56

Recent Advances in Microbiology...........................................52

Technical Writing: A Practical Guide for Engineers and Scientists.........................................................................91

PAT Applied in Biopharmaceutical Process Development And Manufacturing: An Enabling Tool for Quality-by-Design.........59

Red Blood Cell Aggregation....................................................28

Techniques of Non-Clinical Vascular Infusion Technology.......51

Regenerative Engineering.......................................................14

Textbook of Drug Design and Discovery, Fourth Edition.........67

Patient-Focused Network Integration in BioPharma: Strategic Imperatives for the Years Ahead..............................................64

Regenerative Medicine, Stem Cells and the Liver....................47

Textbook of Organic Chemistry................................................8

Regression Models as a Tool in Medical Research....................79

The Image Processing Handbook, Sixth Edition......................31

Reliable Design of Medical Devices, Third Edition...................28 Responsible Nanobiotechnology: Philosophy and Ethics.........45

The Physiology of Bioelectricity in Development, Tissue Regeneration and Cancer.......................................................27

RNA Nanotechnology and Therapeutics...................................8

The Structure of Biological Membranes, Third Edition............47

PCR Technology: Current Innovations, Third Edition................8 Personalized Medicine: Principles and Practices......................37 Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy..........................................................................41 Pharmaceutical Dosage Forms and Drug Delivery, Second Edition.......................................................................68 Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition.........................................................66 Pharmaceutical Process Scale-Up............................................64 Pharmacogenomics of Alcohol and Drugs of Abuse................63 Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Fourth Edition.............................67

S Safety Pharmacology in Pharmaceutical Development: Approval and Post Marketing Surveillance, Second Edition.....67 Sample Size Calculations in Clinical Research, Second Edition.......................................................................80 SAS and R: Data Management, Statistical Analysis, and Graphics.................................................................................89

Theory of Drug Development.................................................81 Theory of Factorial Design......................................................90 Time Series Modeling of Neuroscience Data...........................90 Tissue Engineering and Regenerative Medicine: A Nano Approach...................................................................29 Tissue Engineering: Principles and Practices............................29 Topical Nail Products and Ungual Drug Delivery....................63

Scalable Green Chemistry: Case Studies from the Pharmaceutical Industry.........................................................64

Toxicologic Pathology: Nonclinical Safety Assessment............59

Physics and Chemistry at Low Temperatures..........................27

Science and Techniques of Non-Clinical Vascular Infusion Technology, Two Volume Set..................................................50

Transdermal and Intradermal Delivery of Therapeutic Agents: Application of Physical Technologies.......................................63

Physics for Diagnostic Radiology, Third Edition.......................27

Science of Non-Clinical Vascular Infusion Technology.............50

Translational Medicine: The Future of Therapy.......................63

Physics of Mammographic Imaging........................................79

Second Harmonic Generation Imaging...................................32

Physics of Thermal Therapy: Fundamentals and Clinical Applications............................................................................27

Self-Assembled Peptide Nanostructures: Advances and Applications in Nanobiotechnology........................................45

Transport Phenomena in Biomedical Engineering: Principles and Practices...........................................................30

Physiology, Biophysics, and Biomedical Engineering...............27

Self-Healing at the Nanoscale: Mechanisms and Key Concepts of Natural and Artificial Systems.......................12

Pharmacy: What It Is and How It Works, Third Edition............68 Physical Chemistry for Engineering and Applied Sciences.......27

Pocket Handbook of Nonhuman Primate Clinical Medicine....50 Polymer and Polymer-Hybrid Nanoparticles: From Synthesis to Biomedical Applications.............................12

Simulations in Nanobiotechnology.........................................45 Skin Bioscience: A Molecular Approach....................................8

Polymers for Vascular and Urogenital Applications..................12

Spike Timing: Mechanisms and Function................................57

Practical Guide and Spectral Atlas for Interpretive Near-Infrared Spectroscopy, Second Edition...........................41

Statistical and Computational Methods in Brain Image Analysis...............................................................80

Practical Guide to Clinical Data Management, Third Edition...........................................................................60

Statistical Computing with R..................................................90

Practical Guide to ICP-MS: A Tutorial for Beginners, Third Edition...........................................................................41 Practical Statistical Methods: A SAS Programming Approach...............................................................................79

Statistical Evaluation of Diagnostic Performance: Topics in ROC Analysis............................................................80

Transcranial Brain Stimulation.................................................57

TRP Channels.........................................................................57

U Ultrasonic and Electromagnetic NDE for Structure and Material Characterization: Engineering and Biomedical Applications....12 Understanding Nanomedicine: An Introductory Textbook......91 Usability Testing of Medical Devices.......................................12 Using R for Data Management, Statistical Analysis, and Graphics.................................................................................90

V Vibrational Spectroscopy for Tissue Analysis............................41

Statistical Inference: An Integrated Approach, Second Edition.......................................................................90

Viral Diagnostics: Advances and Applications..........................37

Statistical Methods for Handling Missing Data........................90

Viral Hemorrhagic Fevers........................................................57

Practical Statistics for Medical Research..................................79

Statistical Thinking in Epidemiology.......................................80

Principles of Neural Coding....................................................57

Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition ................................................70

Viral Nanoparticles: Tools for Material Science and Biomedicine.....................................................................30

Prion Biology: Research and Advances....................................52

Vitamin-Binding Proteins: Functional Consequences...............53

W

Statistics for Biomedical Engineering......................................29

Process Validation in Manufacturing of Biopharmaceuticals, Third Edition...........................................................................68

Statistics for Epidemiology......................................................80

Procter; Garry...........................................................................3

Statistics of Medical Imaging..................................................80

Pulmonary Nanomedicine: Diagnostics, Imaging, and Therapeutics...........................................................................28

Stem Cell Engineering: Principles and Practices......................29

Title Index

O

Webb’s Physics of Medical Imaging, Second Edition...............30 Wireless Body Area Networks: Technology, Implementation, and Applications.....................................................................30

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95


A Abuhav; Itay...........................................................................11 Acharya; U. Rajendra..................................................14, 75, 81 Adams; Jesse...........................................................................44 Aggarwal; Bharat B.................................................................46 Ai; Ye......................................................................................38 Ajbar; Abdelhamid..................................................................82 Alamo; Cecilio........................................................................56 Alhumaizi; Khalid....................................................................82 Allen; Linda J. S.......................................................................82 Allen; Matthew J.....................................................................48 Allman; A.R.............................................................................51 Alon; Uri.................................................................................82 Altman; Douglas G.................................................................79

Author Index

Amendola; Vincenzo...............................................................12 Amos; Linda A........................................................................46 Analoui; Mostafa....................................................................77 Anastasio; Mark A...................................................................74 Anderson; Iain A.....................................................................18 Anderson; Stewart..................................................................72 Arthurs; Susan........................................................................55 Arus, Ph.D.; Emeric.................................................................16 Ascione; Alfred N....................................................................17 Ashmead; H. DeWayne.............................................................3 Ashwell; Ken W. S...................................................................50

Cawthon; Andrew G...............................................................48 Cazes; Jack..............................................................................39

Béringue; Vincent...................................................................52

Chader; Gerald J.....................................................................62

Berry; Scott M........................................................................72

Chakraborty; Suman...............................................................42

Best; Serena..............................................................................9

Chan; T.M..............................................................................69

Bidlack; Wayne R....................................................................53

Chandran; Krishnan B.............................................................15

Birkfellner; Wolfgang..............................................................71

Chang; Huan-Tsung...............................................................20

Bisen; Prakash Singh.........................................................35, 40

Chang; Jing............................................................................14

Bizzarri; Anna Rita...................................................................38

Chang; Mark..........................................................................60

Blough; Eric............................................................................25

Chattopadhyay; Subhagata....................................................14

Blum; Kenneth.......................................................................37

Chen; Din...............................................................................73

Blunt; John W.........................................................................61

Chen; Ding-Geng (Din)..........................................................76

Boas; David A.........................................................................21

Chen; Ming-Hui.....................................................................68

Bogdanske; John J...................................................................50

Cheng; Ching-Shui.................................................................90

Bogner; Marilyn Sue...............................................................62

Cheng; Ji-Xin..........................................................................73

Bohlin; Lars.............................................................................61

Cheung; Ying Kuen................................................................73

Bollen; Peter J. A.....................................................................48

Chiao; Jung-Chih......................................................................9

Bonilla; Jose V.........................................................................35

Chiao; Mu................................................................................9

Borkowski; Gary L...................................................................48

Chi-Leung; Hui.........................................................................5

Bouchonnet; Stéphane...........................................................39

Chin; Richard..........................................................................59

Bourtzis; Kostas......................................................................51

Cho; Sang Hyun.....................................................................42

Boutron; Isabelle.....................................................................60

Choi; Taeryon.........................................................................86

Bradley; Richard.....................................................................19

Choudhary; Vikas...................................................................24

Brahmachari; Goutam............................................................65

Chough; Keumhee Carrière....................................................85

Branscum; Adam J. ................................................................85

Chow; Shein-Chung.........................................................60, 80

Brayton; Cory.........................................................................48

Chowriappa; Pradeep.............................................................69

Brenner; Sara..........................................................................19

Christensen; Ronald................................................................85

Bretz; Frank............................................................................60

Chung; Moo K.......................................................................80

Bretz; Frank............................................................................78

Ciurczak; Emil W.....................................................................39

Brock; Kristy Kay.....................................................................31

Ciurczak; Emil W.....................................................................41

Broemeling; Lyle D.................................................................70

Clemons; Donna J..................................................................48

Bronzino; Joseph D........... 10, 13, 16, 19,24, 26, 29, 30, 37, 77

Clontz; Lucia..........................................................................52

Brooks; Steve..........................................................................87

Codee; Jeroen...........................................................................4

Backman; Vadim.....................................................................13

Broom; Mark..........................................................................82

Colegate; Steven M..................................................................3

Bader; Augustinus...................................................................42

Broström; Göran.....................................................................74

Colilla; Montserrat..................................................................16

Badilescu; Simona...................................................................17

Bryce; C. F. A..........................................................................51

Collaert; Nadine.....................................................................34

Bagchi; Debasis......................................................................53

Buckingham; John..................................................................65

Collett; David.........................................................................77

Baggaley; Keith H...................................................................65

Buerk; Donald G.....................................................................10

Cook; Thomas D.....................................................................76

Baio; Gianluca........................................................................72

Burg; Karen J.L. ......................................................................12

Cooper; Caroline......................................................................7

Baltas; Dimos..........................................................................31

Burgess; Rob...........................................................................91

Cosentino; Carlo.....................................................................20

Bandos; Andriy I.....................................................................80

Burgess; Stephen....................................................................89

Courtney; Angela...................................................................50

Bandyopadhyay; Anirban.......................................................44

Burkowski; Forbes J.................................................................68

Cox; Guy................................................................................79

Banerjee; Sudipto...................................................................88

Burns; Donald A.....................................................................39

Crowder; Martin J...................................................................78

Banerjee; Sudipto...................................................................88

Burns; Mark D........................................................................58

Crowley; John.........................................................................75

Banga; Ajay K.........................................................................63

Bustin; Stephen A.....................................................................8

Crozier; Alan...........................................................................66

Bar-Cohen; Yoseph.................................................................18

Bux; Faizal..............................................................................33

Asif; Erfan Syed.......................................................................59 Asif; Syed Erfan.......................................................................28 Athanasiou; Kyriacos A...........................................................15 Atlas; Ronald M......................................................................51 Ayyachamy; M.......................................................................33 Azevedo; Vasco.......................................................................36

B

96

Berard; Felipe M. ...................................................................48 Berglund; Patricia A................................................................71

Barh; Debmalya................................................................36, 37 Barillot; Emmanuel.................................................................69 Barnett; Adrian.......................................................................84 Baskurt; Oguz.........................................................................28 Bates; Declan..........................................................................20 Bauer; Sebastian.....................................................................69 Bawa; Raj................................................................................26 Begg; Rezaul...........................................................................21 Bender; David A.......................................................................7 Benedict, Ph.D.; Stanley H......................................................32 Benkeblia; Noureddine...........................................................63 Bennett; B. Taylor...................................................................48 Ben-Tal; Nir..............................................................................7

C

D da Silva; Ana Luisa Daniel.......................................................25

Cabrini; Stefano......................................................................12

Dakshinamurti; Krishnamurti..................................................53

Cadenas; Enrique....................................................................47

Dakshinamurti; Shyamala.......................................................53

Calzone; Laurence..................................................................69

Dancey; Janet E......................................................................46

Campagnola; Paul J................................................................32

Danguy; André.......................................................................47

Campilho; Aurelio...................................................................75

Danneman; Peggy J................................................................48

Cannistraro; Salvatore.............................................................38

Darling; Eric M.......................................................................15

Cannon; John B......................................................................66

Darvas; Ferenc..........................................................................4

Cao; Dong-Sheng...................................................................37

Dasgupta; Amitava.................................................................63

Carlin; Bradley P..........................................................72, 85, 88

Datta; Ashim K.......................................................................16

Castillo; Jaime.........................................................................45

Davidian; Marie......................................................................89

Castillo-León; Jaime................................................................36

Davidson; Michael W..............................................................81

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Flower; M A............................................................................30 Forsythe; Chris........................................................................53

De Bartolo; Loredana..............................................................42

Fortman; Jeffery D..................................................................48

de la Chapelle; Marc Lamy.....................................................42

Foulkes; Frank R......................................................................27

de Leon; Alexander R..............................................................85

Frei; Mark G...........................................................................55

Demain; Arnold L...................................................................51

Freivalds; Andris......................................................................13

DeMets; David L.....................................................................76

Friedman; Adam.....................................................................25

Dendy; Philip Palin.................................................................27

Fries; Richard C.................................................................19, 28

Der; Geoff........................................................................71, 75

Frokjaer; Sven.........................................................................66

Desu; Hari R............................................................................67

Frydenberg; Morten...............................................................76

Diakides; Mary........................................................................77

Fuentes; Montserrat................................................................87

Dias; Miguel Sales...................................................................14

Fukuda; Toshio.......................................................................25

Diggle; Peter..........................................................................87

Fung; Glenn...........................................................................22

DiLorenzo; Patricia M.............................................................57 Dimaki; Maria.........................................................................36 Dmitrienko; Alex.....................................................................78 Dobson; Annette J..................................................................84 Dodson; Ronald F...................................................................58 Donegan; John.......................................................................42 Dormán; György......................................................................4 Douglas; Fred A......................................................................48 Draghici; Sorin........................................................................69 Drăghici; Sorin........................................................................70 Dua; Sumeet....................................................................69, 81 Dubey; Akhilesh......................................................................32 Dufrene; Yves.........................................................................42 Dunscombe; Peter..................................................................28 DuRaine; Grayson D...............................................................15 Dutta; Joydeep.......................................................................43 Dwivedi; Yogesh.....................................................................55

E

G

H Haddon; Malcolm..................................................................83 Haghi; A. K.............................................................................44 Haider; Syed Imtiaz..........................................................28, 59 Hale; Kelly S............................................................................53 Hammar; Samuel P.................................................................58 Handfield; Robert...................................................................63 Handfield; Robert...................................................................64 Hanrahan; Grady....................................................................38 Hansen; Charles M...................................................................6 Hanson; Timothy E.................................................................85 Hardin; James W.....................................................................87 Hardisty; Jerry F.......................................................................59 Hardman; Craig D..................................................................50

Gabrielsson; Johan............................................................64, 67

Harper; Claudia......................................................................49

Gad; Shayne C.......................................................................67

Hau; Jann...............................................................................49

Galecki; Andrzej T...................................................................88

Hay; David C..........................................................................47

Gama; Miguel..........................................................................9

Hayes; Richard J......................................................................73

Gamerman; Dani....................................................................90

Haynes; William M..................................................................91

García; Miguel Manzano........................................................16

Hazelwood; Vikki....................................................................16

Garcia; Nuno M......................................................................14

He; Hua..................................................................................85

Garvey; Paul R........................................................................83

He; Weixuan...........................................................................62

Gatenholm; Paul.......................................................................9

He; Yan.....................................................................................6

Gaudioso; Jennifer..................................................................51

Healing; Guy....................................................................50, 51

Gelfand; Alan E.................................................................87, 88

Heaton; Brian.........................................................................27

Gelman; Andrew....................................................................87

Hedaya; Mohsen A.................................................................64

Genten; Franck ......................................................................47

Heeringa; Steven G.................................................................71

Georgiev; Vassil St..................................................................91

Heiss; John D..........................................................................55

Ghetti; Francesco......................................................................5

Heldman; Dennis R.................................................................34

Gilks; W.R...............................................................................89

Hernan; Miguel A...................................................................73

Gill; Jeff...................................................................................84

Herold; Keith E.......................................................................18

Ebadi; Manuchair ..................................................................56

Gilthorpe; Mark S...................................................................80

Hewett; Terry A......................................................................48

Eckelman; William C...............................................................32

Giordano; James ....................................................................56

Hilbe; Joseph M..........................................................87, 88, 89

Eiceman; G.A..........................................................................40

Globig; Sabine........................................................................65

Hill, Jr.; Herbert H...................................................................40

Ekstrøm; Claus Thorn.............................................................83

Goins; Beth A.........................................................................78

Hillery; Anya M.......................................................................67

El-Baz; Ayman.........................................................................77

Gonnella; Nina C....................................................................40

Hiremath; Shobha Rani R........................................................61

Elias; Dirk Christian.................................................................14

Good; Phillip I.........................................................................71

Hirose; Keiko..........................................................................46

Elias; Eldho.............................................................................44

Gopinath; Chirukandath.........................................................59

Hjorth; Stephan......................................................................64

Elman; Noel..............................................................................3

Gordon; Paul M.K...................................................................69

Hoering; Antje........................................................................75

El-Mansi; E. M. T.....................................................................51

Gottfried; Jay A.......................................................................56

Hollinger; Jeffrey O...................................................................7

Enache; M................................................................................6

Green; Owen P.................................................................50, 51

Holmgren; Eric B....................................................................81

Eom; Kilho..............................................................................45

Green; Sherril L.......................................................................49

Hoover; Dallas G.....................................................................34

Eren; Halit...............................................................................23

Griesbeck; Axel.........................................................................5

Hornyak; Gabor L...................................................................43

Everitt; Brian S............................................................71, 75, 84

Grigoryan; Artyom M.............................................................22

Horton; Nicholas J............................................................89, 90

F Falissard; Bruno......................................................................71 Faraway; Julian J...............................................................86, 88 Federici; Stefano.....................................................................15 Fedorov; Valerii V....................................................................79 Felli; James..............................................................................72 Field; Garrett..........................................................................48 Field; Karl J.............................................................................48 Firman; Keith..........................................................................36 Fischer-Cripps; Anthony Craig..................................................4 Fisher; John P..........................................................................29 Fisher; Robert J.......................................................................30 Fitzmaurice; Garrett................................................................89

Grigoryan; Merughan M........................................................22

Hoskin; Peter J........................................................................31

Grinberg; Nelu.................................................................37, 38

Hosmane; Narayan S..............................................................33

Grote; James...........................................................................11

Hothorn; Torsten..............................................................60, 84

Grunwald; Armin ...................................................................45

Hovgaard; Lars.......................................................................66

Grunwald; Peter.......................................................................4

Howard; Gary C.....................................................................62

Grushka; Eli......................................................................37, 38

Hsiao; Chin-Fu........................................................................60

Guha; Sushovan.....................................................................46

Hu; Jerry C..............................................................................15

Guo; Peixuan............................................................................8

Hu; Wei-Shou.........................................................................59

Gupta; V. K.............................................................................33

Hubbard-Van Stelle; Scott.......................................................50

Gustafson; Paul.......................................................................85

Hunter Jr.; William..................................................................65

Gutierrez-Galvez; Augustin.....................................................56

Hunter; Ross...........................................................................46

Guttman; András......................................................................4

Hupe; Philippe........................................................................69

Guttorp; Peter........................................................................87

Husson; Francois.....................................................................86 Huston; Ronald L....................................................................21

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Author Index

Dawood; Mohammad............................................................31 Day; Richard N.......................................................................81

97


I

Koenig; Stefan........................................................................64

Lin; James C............................................................................20

Kole; Chittaranjan...................................................................35

Liu; Aiyi..................................................................................80

Kolev; Bozhidar Dimitrov........................................................54

Liu; Dongyou.........................................................................52

Kong; Hyunjoon ....................................................................37

Liu; Jen-pei.............................................................................60

Konofaos; Nikos......................................................................44

Liu; Yunhui.............................................................................13

Kováč; Pavol..............................................................................4

Ljungberg; Michael................................................................31

Kraitchman; Dara L.................................................................47

Lloyd; Andrew W....................................................................67

Krishnan; Sunil..................................................................42, 46

Lobel; Leslie............................................................................37

Jackson; Todd A......................................................................48

Krishnaswamy; N R.................................................................65

Lopez-Munoz; Francisco.........................................................56

Jacobson; Elliott......................................................................50

Krogsgaard-Larsen; Povl.........................................................67

Louis; Thomas A.....................................................................85

Jain; Parijat...............................................................................6

Krull; Ira S...............................................................................39

Louzada-Neto; Francisco........................................................90

Jarvis; Suzi..............................................................................53

Kuang; Yang...........................................................................82

Low; Duncan..........................................................................59

Jewell; Nicholas P....................................................................80

Kubby; Joel A..........................................................................30

Lundblad; Roger L..........................................................4, 6, 52

Jiang; Xiaoyi...........................................................................31

Kucklick; Theodore R..............................................................24

Jin; Jung-II...............................................................................11

Kuiken; Todd..........................................................................29

Johnson; Dallas E....................................................................84

Kumar Parashar; Rakesh............................................................5

Johnson; Wesley O. ................................................................85

Kumar; Arun...........................................................................25

Jones; D.S...............................................................................81

Kundu; Tribikram....................................................................12

Jones; Galin............................................................................87

Kuo; Lynn...............................................................................68

Jones; Susan...........................................................................55

Kurniawan; Sri........................................................................15

Imae; Toyoko............................................................................8 Imai; Kazuhiro........................................................................41 Indrayan; Abhaya...................................................................77 Iniewski; Krzysztof......................................................24, 35, 41 Ison; Keith..............................................................................24

J

Author Index

Juneja; Lekh R.........................................................................61 Jurczyk; Mieczyslaw................................................................10 Juul; Svend.............................................................................76

K

98

L

M Ma; Guanghui........................................................................36 Macdonald; Fiona.....................................................................6 MacDonald; Iain L..................................................................87 Madigan; Margaret A.............................................................37 Madou; Marc J........................................................................20 Madsen; Ulf............................................................................67 Mahato; Ram I..................................................................67, 68

La Riviere; Patrick....................................................................74

Maibach; Howard I.................................................................63

Lahtinen; Sampo....................................................................36

Maitland; Duncan...................................................................17

Lai; Daniel Tze Huei................................................................21

Man; K.F.................................................................................69

K. Hansen; Axel......................................................................48

Lai-Fan; Wong..........................................................................5

Manchester; Marianne............................................................30

Kadokawa; Jun-ichi...................................................................8

Lai-Kwan; Chau......................................................................20

Manduchi; Roberto................................................................15

Kagadis; George C..................................................................75

Lambert; Paul C......................................................................74

Manly; Bryan F.J......................................................................84

Kaiyu; Raymond Tong............................................................16

Lamm; Ehud...........................................................................81

Mansour; Heidi M...................................................................25

Kalcher; Kurt...........................................................................34

Lamoureux; Victor S...............................................................49

Marco; Santiago.....................................................................56

Kamath; Markad V..................................................................21

Land; Kenneth C....................................................................70

Markey; Mia K........................................................................79

Kane; Suzanne Amador..........................................................22

Langer; Steve G......................................................................75

Markram; Henry.....................................................................54

Kaneko; Yoshiro........................................................................8

Langford; Richard...................................................................54

Marks; Robert S......................................................................37

Kapoor; Mahendra P...............................................................61

Langman; Loralie J. ................................................................63

Marr; Rena.............................................................................48

Karpas; Z................................................................................40

Lantada; Andres Diaz..............................................................10

Marsh; Derek............................................................................6

Kaser; Matthew R...................................................................62

Laplante; Phillip A...................................................................91

Martin; Brent J........................................................................48

Kateb; Babak..........................................................................55

Laud; Purushottam.................................................................76

Marwaha; S.S. .......................................................................33

Kaufman; Peter B....................................................................34

Laurencin; Cato T...................................................................14

Matcher; Steve ......................................................................26

Kavanagh; Brian D..................................................................32

Law; Victor J...........................................................................26

Matchett; C. Andrew..............................................................48

Kawata; Satoshi......................................................................12

Lawrence; Christian ...............................................................49

Matchett; Christian C.............................................................58

Kelly; William N......................................................................68

Lawson; Andrew B..................................................................72

Mathiassen; Svend Erik...........................................................26

Kendler; Jonathan...................................................................12

Lawson; John..........................................................................86

Matson; Robert S....................................................................59

Kenkel; John...........................................................................38

Le; Sebastien .........................................................................86

Matteoli; Enrico........................................................................6

Kessel; Amit..............................................................................7

Lee; J. Jack..............................................................................72

Mazzoleni; Ilaria......................................................................46

Khan; Firdos Alam..................................................................33

Lei; Tianhu..............................................................................80

McCrea; Rachel S...................................................................83

Khan; Jamil.............................................................................30

Leonov; Sergei L.....................................................................79

Meigooni; Ali S.......................................................................31

Khan; Yusuf............................................................................14

Leray; Claude...........................................................................7

Meiselman; Herbert J..............................................................28

Khang; Gilson.........................................................................21

Levin; Michael........................................................................64

Mendelson; Mel I...................................................................23

Khriachtchev; Leonid..............................................................27

Lewis; Cornelius......................................................................20

Meneghetti; Moreno..............................................................12

Kilkenny; Dawn......................................................................22

Lewis; Paul O..........................................................................68

Menezes; Jose C.....................................................................59

Kim; Dongho..........................................................................11

Li Fong Yau; Sam....................................................................41

Meng; Xiao-Li.........................................................................87

Kim; Jae Kwang......................................................................90

Li; Arthur................................................................................74

Mentzer; Mark A.....................................................................32

Kim; Se-Kwon...................................................................11, 66

Li; Guangyong........................................................................42

Mercanzini; André..................................................................55

King; M. A..............................................................................31

Li; Hong-Dong.......................................................................37

Micou; Melissa Kurtis..............................................................22

King; Paul H...........................................................................19

Li; Jun.....................................................................................18

Migon; Helio S.......................................................................90

Kleinman; Ken..................................................................89, 90

Li; Junjie....................................................................................5

Mikos; Antonios G..................................................................29

Klemm; Dieter..........................................................................9

Li; Wan-Ju...............................................................................29

Milano; Franco.......................................................................20

Knoll; Wolfgang......................................................................35

Liang; Hualou.........................................................................19

Milliken; George A..................................................................84

Kobayashi; Katsumi................................................................83

Liang; Yizeng..........................................................................37

Mills, III; Terry.........................................................................58

Koch; Mel...............................................................................59

Lim; Teik-Cheng.....................................................................14

Milne; Christopher-Paul .........................................................63

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Mitra; Sushanta K...................................................................42 Mittra; James..........................................................................63 Moher; David.........................................................................60 Molenberghs; Geert...............................................................89 Molina, M.D.; D. K.................................................................58 Molyneux; Russell J...................................................................3 Moore; James ........................................................................17 Moore; John J.........................................................................43 Morgan; Byron J. T.................................................................83 Morgan; Stephen...................................................................26 Moros; Eduardo .....................................................................27 Mostaert; Anika......................................................................53 Moulton; Lawrence H.............................................................73 Movasaghi; Zanyar.................................................................41 Muftuler; L. Tugan..................................................................32 Muller; Peter...........................................................................72 Mundt; Arno J........................................................................28 Munro; Murray H. G...............................................................61 Murff; Samuel James...............................................................68 Murphy; Martin J....................................................................70 Murray; Micah M...................................................................57 Murthy; S Narasimha..................................................63, 61, 65 Murthy; Sreekant....................................................................49

N

P Packer; Lester.........................................................................47 Packirisamy; Muthukumaran..................................................17 Padgett; Lakshmi....................................................................79 Pages; Jerome.........................................................................86 Palaniswami; Marimuthu........................................................21 Pan; Dipanjan.........................................................................26 Panesar; P. S...........................................................................33 Panzeri; Stefano......................................................................57 Parker; Rolland S.....................................................................55 Pastorin; Giorgia.....................................................................10 Patel; Vinood..........................................................................10 Paulus; Walter.........................................................................57 Pavone; Francesco S...............................................................32 Pawlicki; Todd .......................................................................28 Peace; Karl E...........................................................................73 Peace; Karl E...........................................................................76 Pearce; Cedric........................................................................91 Peattie; Robert A.....................................................................30 Peer; Dan...............................................................................11 Pennathur; Sumita..................................................................44 Perfetti; Thomas A..................................................................58 Pergolizzi, Jr.; Joseph V............................................................54 Persaud; Krishna C..................................................................56 Peterson; Donald R.......... 10, 13, 16, 19, 24, 26, 29, 30, 37, 77 Pezzotti; Giuseppe..................................................................14

Nadeau; Jay............................................................................39

Pfeiffer; Ronald F.....................................................................56

Nagatomi; Jiro........................................................................24

Phillips; William T....................................................................78

Nagy; John.............................................................................82

Pillai; C. N................................................................................8

Najarian; Kayvan....................................................................30

Pillai; K. Sadasivan..................................................................83

Nandi; Nilashis.........................................................................5

Pillay; Michael........................................................................35

Narang; Ajit S...................................................................67, 68

Pinto; Cesar Ariel....................................................................83

Neu; Björn .............................................................................28

Pispas; Asterios.......................................................................12

Neuhauser; Markus................................................................89

Pitris; Constantinos.................................................................21

Newman; Michael C.................................................................6

Placidi; Giuseppe....................................................................77

Ng; E. Y. K. ............................................................................75

Plank; Michael........................................................................81

Niazi; Sarfaraz K.....................................................................64

Polansky; Alan M....................................................................88

Ninan; Neethu.......................................................................44

Popp; James A........................................................................59

Noel; Rebecca........................................................................72

Porreca; Frank.........................................................................54

Nolan; Tania.............................................................................8

Preedy; Victor R......................................................................10

Norde; Willem........................................................................34

Preedy; Victor R......................................................................46

Nordlund; Thomas M.............................................................28

Preziosi; Luigi..........................................................................81

Northrop; Robert B.................................................................15

Priyadarshy; Satyam...............................................................42

Nyberg; Fred..........................................................................62

Prokscha; Susanne..................................................................60 Pucci; Annemarie....................................................................42

O

Pullar; Christine E...................................................................27

O’ Connell; John P....................................................................6

Pumera; Martin......................................................................25

Oberg; P. Ake.........................................................................17

Putnam; Andrew J..................................................................37

Oelgemöller; Michael...............................................................5

Putter; Hein............................................................................73

Ohno-Machado; Lucila...........................................................80 Okubo; Tsutomu....................................................................61

Q

Rainsford; Kim D.....................................................................66 Rakovich; Yury........................................................................42 Ramachandra; Renuka............................................................54 Ramakrishna; Seeram...............................................................9 Ramalingam; Murugan.......................................................9, 29 Ramanujam; Nimmi...............................................................21 Ramaswamy; H. N..................................................................83 Ramsland; Paul A......................................................................8 Ranade; Vasant V....................................................................66 Rangelou; Stanislav ................................................................12 Rankin Riley; Margaret............................................................50 Rao; Kalipatnapu N.................................................................58 Rao; R. Bharat.........................................................................22 Rao; Theertham......................................................................61 Rasooly; Avraham...................................................................18 Rathore; Anurag S..................................................................68 Ravaud; Philippe.....................................................................60 Ray; Abhijit ............................................................................62 Raychaudhuri; Siba P..............................................................53 Reddi; A. Hari.........................................................................15 Rehman; Ihteshamur..............................................................41 Rehman; Shazza.....................................................................41 Reisner; David E......................................................................18 Renaud; Philippe ...................................................................55 Richardson; S..........................................................................89 Ripamonti; Ugo......................................................................29 Ritchie; Gary E........................................................................41 Ritter; Arthur B.......................................................................16 Rittgers; Stanley E...................................................................15 Rizopoulos; Dimitris ...............................................................76 Rizzo; Maria L.........................................................................90 Roberson; James Conrad........................................................58 Roberts; Andrew D.................................................................65 Robins; James M.....................................................................73 Robinson; Andrew..................................................................89 Robinson; Peter N...................................................................69 Rockette; Howard E................................................................80 Rodgman; Alan.......................................................................58 Rodrigues; Joel Jose P.C...........................................................14 Rodriguez; Raymond L...........................................................53 Rogers; Ben............................................................................44 Rosales; Romer.......................................................................22 Rose; Felicity R........................................................................26 Rosen; Yitzhak..........................................................................3 Rosner; Gary L........................................................................76 Rossini; Paolo M.....................................................................57 Roy; Michael J.........................................................................33 Roy; Sashwati.........................................................................53 Royston; Patrick .....................................................................74 Ruano; Gualberto ..................................................................37 Rubenzer; Bernard..................................................................76

Ollis, Jr.; Robert J.....................................................................58

Qian; Shizhi............................................................................38

Rudolph; Alan S......................................................................54

Olsen Alstrup; Aage K.............................................................48

Qin; Qing-Hua........................................................................23

Russ; John C...........................................................................31

Orrenius; Sten........................................................................47

Quattrocchi; Umberto............................................................58

Ruzek; Daniel ...................................................................45, 57

Osorio; Ivan............................................................................55

Quiroga; Rodrigo Quian.........................................................57

Rychtar; Jan............................................................................82

Ouahab; Lahcene...................................................................35 Ouwehand; Arthur C..............................................................36 Ozaki; Tohru...........................................................................90 Ozturk; Sadettin.....................................................................59

Author Index

Miniussi; Carlo........................................................................57 Mishra; Neeraj .......................................................................32

S

R Rabe-Hesketh; Sophia.......................................................75, 87

Saba; Luca..............................................................................78

Radvansky; Gabriel A..............................................................53

Saboktakin; Mohammed Reza ...............................................61

Raffa; Robert B........................................................................54

Sadeghi; Saman........................................................................5

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99


Author Index 100

Sahota; Pritam S.....................................................................59

Smith; David S........................................................................22

Thassu; Deepak .....................................................................62

Salerno; Reynolds M...............................................................51

Smith; Martyn R.....................................................................29

Thomas; Robert......................................................................41

Sall; Amadou..........................................................................37

Smith; Michael B......................................................................7

Thompson; Michael..................................................................5

Salminen; Seppo....................................................................36

Smith; Paul E............................................................................6

Thompson; Simon G..............................................................89

Salyanov; V.I.....................................................................42, 44

Sofer; Gail...............................................................................68

Throne-Holst; Harald..............................................................42

Samuelsson; Gunnar...............................................................61

Soh; Jung...............................................................................69

Tian; Guo-Liang......................................................................88

Santos; Dana M................................................................21, 52

Sørensen; Helle.......................................................................83

Tibbals; H.F.............................................................................43

Sashegyi; Andreas...................................................................72

Soto; Eivind............................................................................42

Tibbals; Harry F.......................................................................24

Sasso; Luigi.............................................................................45

Spencer; Jeremy P. E...............................................................66

Toko; Kiyoshi..........................................................................15

Sau-Fun; Ng.............................................................................5

Spiegelhalter; David...............................................................89

Toomingas; Allan....................................................................26

Scalliet; Pierre.........................................................................28

Splinter; Robert......................................................................30

Tor; Yitzhak.............................................................................36

Scemes; Eliana........................................................................54

Sprawls; Perry.........................................................................20

Tornqvist; Ewa Wigaeus..........................................................26

Schäfers; Klaus........................................................................31

Spray; David C.......................................................................54

Trindade; Tito.........................................................................25

Schaffer; David.......................................................................29

Sprent; Peter..........................................................................85

Tringali; Corrado....................................................................65

Schapiro; Steven J...................................................................49

Srinivas; Iyer...........................................................................45

Tsvetkova; Larisa ....................................................................53

Schattschneider; Peter............................................................40

Srivastava; Punit Kumar..........................................................62

Tu; Xin M...............................................................................85

Scherer; Marcia......................................................................15

Srivatsa; G. Susan...................................................................35

Tu; Yu-Kang............................................................................80

Schiessel; Helmut....................................................................46

Stanney; Kay M......................................................................53

Tuchin; Valery V......................................................................14

Schiffman; Beth M..................................................................50

Steinmetz; Nicole F.................................................................30

Tyler; Christopher W...............................................................19

Schlesinger; David J................................................................32

Stephanova; Diana Ivanova....................................................54

Schneider; Hans-Jörg................................................................3

Stough; Con Kerry Kenneth....................................................61

Scholey; Andrew.....................................................................61

Strand; Sven-Erik..............................................................20, 31

U Ude; George...........................................................................35 Undey; Cenk..........................................................................59

Scholl; Gerd............................................................................42

Strandbakken; Pal...................................................................42

Schook; Lawrence B...............................................................37

Strandberg; Kenneth M..........................................................67

Schreiner; Steven....................................................................24

Street; Laurence......................................................................22

Schroeder; Valerie...................................................................48

Strochlic; Allison Y...................................................................12

Schultz; Aimee E.....................................................................29

Stroman; Patrick W.................................................................74

Vach; Werner..........................................................................79

Scianna; Marco.......................................................................81

Stromgaard; Kristian...............................................................67

Valdevit; Antonio....................................................................16

Sebastian; Mathew.................................................................44

Su; Zhi-Guo............................................................................36

Valentine; David L...................................................................56

Sebastian; Mathew.................................................................44

Subramanian; Thyagarajan.....................................................54

Valentine; Raymond C............................................................56

Seco; Joao..............................................................................31

Suckow; Mark A...............................................................48, 49

Vallet-Regí; María....................................................................16

Seeman; Jennifer L..................................................................48

Sujatha; R...............................................................................83

Vallittu; Pekka.........................................................................29

Segev; Idan............................................................................54

Sun; Dong..............................................................................13

van Buuren; Stef.....................................................................86

Semenov; S.V..........................................................................42

Sun; Jianguo...........................................................................76

van de Weert; Marco..............................................................66

Sensen; Christoph W..............................................................69

Suri; Jasjit S.................................................................75, 77, 78

van der Marel; Gijsbert.............................................................4

Serda; Rita Elena.....................................................................23

Svancara; Ivan........................................................................34

van Houwelingen; Hans..........................................................73

Shalaby; Shalaby W................................................................12

Svendsen; Winnie Edith....................................................36, 45

Venselaar; Jack........................................................................31

Shalaby; Waleed ....................................................................12

Swarbrick; James....................................................................67

Verbeke; Geert........................................................................89

Shalliker; R. Andrew................................................................39

Swartz; Michael E...................................................................39

Verhaegen; Frank....................................................................31

Shankar; Latha........................................................................42

Swearengen; James R.............................................................47

Vert; Jean-Philippe .................................................................69

Shao; Jun................................................................................80

Swindle; M. Michael...............................................................51

Vicente; Antonio A..................................................................34

Shao; Jun................................................................................90

Swing; Sonya P.......................................................................48

Victor; Jonathan D..................................................................57

Sharma; Anjana......................................................................35

Szabo; Laszlo F........................................................................65

Vij; Neeraj...............................................................................28

Sharon; Madhuri....................................................................18

Szycher, Ph.D; Michael...........................................................29

Villano; Jason..........................................................................48

Sharon; Maheshwar................................................................18 Sharp; Patrick.........................................................................48 Sheskin; David J......................................................................87 Shi; Jian Qing.........................................................................86 Sibold; Amber L......................................................................48 Silverman; Jerald.....................................................................49 Simon; Mathew J....................................................................58 Simpson; Richard C................................................................19 Singh; Sunit K...................................................................45, 57 Sitharaman; Balaji...................................................................25 Skrondal; Anders....................................................................87 Skuridin; S.G.....................................................................42, 44 Sleeman; B.D..........................................................................81 Small; Michael .......................................................................82 Smeeton; Nigel C...................................................................85

T Tabakov; Slavik.......................................................................20 Tabakov; Slavik.......................................................................24 Tagawa; Tatsuo.......................................................................17 Tallarida; Ronald J...................................................................54

Unger; Ron.............................................................................81 Upton; Adrian.........................................................................21

V

Vincent; Julian........................................................................18 Vo-Dinh; Tuan........................................................................17 von Wright; Atte.....................................................................36 Vytras; Karel............................................................................34

W

Tamhane; Ajit C......................................................................78

Walcarius; Alain......................................................................34

Tamura; Toshiyo.....................................................................17

Walker; John D.........................................................................6

Tan; Jen Hong.........................................................................75

Wall; Michael E.......................................................................70

Tang; K.S................................................................................69

Wallace; Mark T......................................................................57

Tang; Man-Lai .......................................................................88

Wang; Hansheng....................................................................80

Tang; Wan..............................................................................85

Wang; Perry G........................................................................62

Teixeira; Jose A........................................................................34

Wang; Ruikang K....................................................................14

Teixeira; Marie B.....................................................................19

Wanunu; Meni........................................................................36

Tercero; Carlos........................................................................25

Watanabe; Mari......................................................................21

Terwinghe; Eddy.....................................................................47

www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-561-994-0555 • +44 (0) 1235 400 524


Wax; Adam.............................................................................13

Zhang; Hao............................................................................14

Webster; John G.....................................................................23

Zhang; Helen H......................................................................34

Wegrzyn; Renee D..................................................................54

Zhang; Mingjun.....................................................................42

Weiner; Daniel........................................................................67

Zhang; Sam........................................................................9, 11

Welch; Kathleen B..................................................................88

Zhao; Weimin.........................................................................66

Welch; Michael J...............................................................32, 34

Zhu; Michael X.......................................................................57

West; Brady T....................................................................71, 88

Zinovyev; Andrei....................................................................69

Westfall; Peter.........................................................................60

Zotov; Mikhail V.....................................................................53

Weyer; Lois.............................................................................41

Zou; Kelly H............................................................................80

Wheeler; Matthew B...............................................................34

Zucchini; Walter.....................................................................87

Wick; Charles H......................................................................40 Wide; Peter.............................................................................71 Wiklund; Michael E.................................................................12 Wilkinson; Darren J.................................................................70

Winkelstein; Beth A.................................................................26 Wong; Joyce Y.........................................................................10 Wood; Andrew W...................................................................27 Wood; Simon.........................................................................87 Woodward; Mark....................................................................74 Woodward; Phil......................................................................72 Workman, Jr.; Jerry..................................................................41

Author Index

Willson; Keith.........................................................................24

Wszolek; Zbigniew K..............................................................56 Wu; Chengtie.........................................................................14 Wu; Guoyao.............................................................................3 Wu; Joseph C..........................................................................47 Wu; Nianqiang.......................................................................18 Wu; William............................................................................34

X Xi; Ning..................................................................................42 Xiao; Yin.................................................................................14 Xie; Xiaoliang Sunney.............................................................73 Xie; Yubing.............................................................................25 Xu; Qing-Song.......................................................................37 Xu; Rensheng.........................................................................66

Y Yalkowsky; Samuel H................................................................6 Yang; Sherry X........................................................................46 Yang; Yang.............................................................................70 Yao; Fanglian............................................................................5 Yao; Kangde.............................................................................5 Ye; Yang.................................................................................66 Yeagle; Philip L.......................................................................47 Yevdokimov; Yuri M..........................................................42, 44 Yin; R.J....................................................................................69 Yin; Yuji....................................................................................5 Yogananda; C. S.....................................................................83 Yoganathan; Ajit P...................................................................15 Youell; James..........................................................................36 Yu; Wenwei............................................................................14 Yuce; Mehmet R.....................................................................30 Yuriev; Elizabeth.......................................................................8

Z Zambare; Vasudeo..................................................................36 Zaveri; Hitten P.......................................................................55 Zchori-Fein; Einat...................................................................51 Zeng; Haishan........................................................................20

For more information and a complete list of titles, visit us at www.crcpress.com

101


Notes 102

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Visit us online at

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In the Americas Sales Office - CRC Press 6000 Broken Sound Parkway, NW, Suite 300, Boca Raton, FL 33487, U.S.A. Within the Continental USA - Tel: 800-272-7737 • Fax: 800-374-3401 • orders@taylorandfrancis.com Outside the Continental USA - Tel: 561-994-0555 • Fax: 561-361-6018 • international.orders@taylorandfrancis.com Dennis Weiss Tel: 561-998-2510 Fax: 561-998-2580 e-mail: dennis.weiss@taylorandfrancis.com

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Customer Services Book orders should be addressed to the appropriate overseas agent or the Customer Service Department at Bookpoint:

Taylor & Francis Bookpoint 130 Milton Park, Abingdon, Oxon OX14 4SB Tel: +44 (0) 1235 400 524 Fax: +44 (0) 1235 400 525 e-mail (UK): uktrade@tandf.co.uk e-mail (international): international@tandf.co.uk

Standing Orders

If you would like to receive books on our improved preselective standing order system, or if you would like to have further information about this service, please contact your area manager or Customer Services Department.

Foreign Rights Adele Parker e-mail: adele.parker@tandf.co.uk

Exhibitions

103

Katie Gilbert Exhibitions Manager Tel: +44 (20) 7017 6310 e-mail: katie.gilbert@tandf.co.uk

Caribbean and The West Indies

Australia and New Zealand

Middle East and North Africa

Jasmina Basic Area Sales Manager Milton Park Sales Office Tel: +44 (0) 20 7017 6187 Fax: +44 (0) 20 7017 6748 e-mail: jasmina.basic@tandf.co.uk

CRC Press and Marcel Dekker only Libraries may wish to order from their local bookseller, Palgrave Macmillan or DA Information Services Pty Ltd 648 Whitehorse Road, Mitcham Victoria, Australia Tel: +61 3 9210 7804 Fax: +61 3 9210 7788 www.dadirect.com.au

Jasmina Basic Area Sales Manager – Middle East and Africa Milton Park Sales Office Tel: +44 (0) 20 7017 6187 Fax: +44 (0) 20 7017 6748 e-mail: jasmina.basic@tandf.co.uk Zoe Kaviani IPS (Middle East) Ltd P.O. Box 27533 Dubai, UAE Tel: +971 4 238 4001 Fax: +971 4 238 4005 e-mail: itpme@emirates.net.ae Website: http://www.ipsme.com

Australasia Joanne Blackford Milton Park Sales Office Tel: +44 (0) 20 7017 6053 Fax: +44 (0) 20 7017 6748 e-mail: joanne.blackford@tandf.co.uk

Australia Palgrave Macmillan Level 1, 15-19 Claremont Street, South Yarra Melbourne, Vic 3141, Australia Tel: +61 3 9825 1111 Fax: +61 3 9825 1010 e-mail: palgrave@macmillan.com.au www.palgravemacmillan.com.au

Sales Agents

Senior Vice President of Sales

Australia Europa Publications (non-exclusive) James Bennett 3 Narabang Way, Belrose, NSW 2085 Australia Tel: +02 9986 7064 Fax: +02 9986 7030 www.bennett.com.au

Rest of Africa Jasmina Basic Area Sales Manager – Middle East and Africa Milton Park Sales Office


Sub-Saharan Africa (excluding South Africa and Botswana) Julian Russ Tula Publishing Ltd Aristotle House Aristotle Lane Oxford OX2 6TR Tel: +44 (0) 1865 553606 Fax: +44 (0) 1865 517999 e-mail: julian@tulapublishing.co.uk

For all Taylor & Francis Group imprints please order from our Singapore Sales Office Singapore Sales Office Taylor & Francis Asia Pacific 240 MacPherson Road #08-01 Pines Industrial Building Singapore 348574 Tel: +65 6741 5166 Fax: +65 6742 9356 e-mail: sales@tandf.com.sg

Botswana

Hong Kong

Sales Agents

Arthur Oageng Book Promotions/Horizon Books Botswana Gaborone International Finance Park Plot 113-114, Unit 33, Kgale Mews 2, Suite 3 Gaborone, Botswana Tel: +267 393 1194 Fax: +267 392 4908 e-mail: arthur.oageng@online.co.bw

South Africa, Namibia, Lesotho and Swaziland Michelle Symington Book Promotions/Horizon Books PO Box 6836 Roggebaai 8012 South Africa Tel: +27 21 469 8900 Fax: +27 21 469 8903 Fax2Email: 0865314387 e-mail: enquiries@bookpro.co.za

South Asia Ryan Cooper International Sales Manager Milton Park Sales Office Tel: +44 (0) 20 7017 6113 Fax: +44 (0) 20 7017 6748 e-mail: ryan.cooper@tandf.co.uk

India

104

East and Southeast Asia

Taylor & Francis Books India Pvt Ltd. 912 Tolstoy House 15-17, Tolstoy Marg New Delhi 110 001 Tel: +91 (0) 11 2371 2131 +91 (0) 11 2335 1453 Fax: +91 (0) 11 2371 2132 e-mail: inquiry@tandfindia.com

Pakistan M. Anwer Iqbal Book Bird Mian Chambers, 3 Temple Road PO Box 518, Lahore, Pakistan Tel: +92 42 636 7275 Fax: +92 42 636 1370 e-mail: bookbird@brain.net.pk

Japan United Publishers Services Limited 1-32-5 Higashi-shinagawa Shinagawa-ku, Tokyo 140-0002 Tel: +81 (0) 3 5479 7251 Fax: +81 (0) 3 5479 7307 e-mail: info@ups.co.jp Editorial Office

Korea Se-Yung Jun ICK (Information & Culture Korea) 473-19 Seokyo-dong, Mapo-ku Seoul, Korea 121-896 Tel: +82 2 3141-4791 Fax: +82 2 3141-7733 e-mail: cs.ick@ick.co.kr

Taylor & Francis Asia Pacific 23/F., China Online Centre 333 Lockhart Road Wanchai Hong Kong Tel: +852 3966 7002 Jeffrey Lim Books Sales Director Singapore Sales Office e-mail: jeffrey.lim@tandf.com.sg Andrew Kwan Manager e-mail: andrew.kwan@tandf.com.sg

China

Taylor & Francis Asia Pacific Room 1108B, Culture Square No. 59 Jia, Zhongguancun St. Haidian District Beijing 100872 P.R. China Tel: +86 10 82502670 Fax: +86 10 82502566 Jeffrey Lim Books Sales Director Singapore Sales Office e-mail: jeffrey.lim@tandf.com.sg Cynthia Ji Sales Manager e-mail: cynthia.ji@tandf.com.sg

Shanghai Region

Chris Ye Account Manager Room 1410, Jinjiang Xiangyang Tower 993 Nanjing West Road Shanghai 200041 P.R. China Tel: +86 21 22111595 e-mail: chris.ye@tandf.com.sg

Guangdong Region

Cherry Wang Sales Executive e-mail: cherry.wang@tandf.com.sg

Singapore and Indonesia

Mohamed Feroz Assistant Sales Manager Singapore Sales Office e-mail: mohamed.feroz@tandf.com.sg

Malaysia and Brunei

Taylor & Francis Publishing Services Taylor & Francis Asia Pacific No. 23-2, Jalan PJS 8/18 Dataran Mentari 46150 Petaling Jaya Selangor Darul Ehsan Malaysia Tel: +60 (3) 5630 1361 Fax: +60 (3) 5630 1732 David Yeong General Manager Mobile: +60 (0)16 331 9912 e-mail: david.yeong@tandf.com.sg

Thailand

Taylor & Francis Asia Pacific Jeffrey Lim Books Sales Director e-mail: jeffrey.lim@tandf.com.sg Nonglak Sawaithong Account Manager Tel : +66 2 639 1333 ext. 3612 e-mail: s.nonglak@tandf.com.sg

Taiwan

Taylor & Francis Asia Pacific Room 629, 6F, No. 6, Sec. 4, Hsinyi Road Da-an District Taipei 106 Taiwan (R.O.C.) Jeffrey Lim Books Sales Director e-mail: jeffrey.lim@tandf.com.sg Jason Lin Sales Manager Tel: +886 (2) 2551 1266 ext. 6275 e-mail: jason.lin@tandf.com.sg

Philippines, Vietnam and Indo-China Jeffrey Lim Books Sales Director Singapore Sales Office e-mail: jeffrey.lim@tandf.com.sg

Israel and the Palestinian Territories Ryan Cooper International Sales Manager Milton Park Sales Office Tel: +44 (0) 20 7017 6113 Fax: +44 (0) 20 7017 6748 e-mail: ryan.cooper@tandf.co.uk and Rodney Franklin Franklin’s International PO BOX 3772 7, Tel Aviv 61376, Israel Tel: +972 356 00724 Fax: +972 356 00479 e-mail: rodneyf@netvision.net.il

Europe Belgium, The Netherlands, France and Luxembourg Liza Walraven Area Sales Manager Taylor & Francis P.O. Box 447 2300 AK Leiden The Netherlands Tel. 0031 (0) 715243084 F: 0031 (0) 71 523 4571 Mobile: 0031 (0)623849668 e-mail: liza.walraven@informa.com

Nordic Countries Eva Nyika Sales Representative Taylor & Francis Scandinavia Kungsbroplan 3 A, 1st Floor P.O Box 3255 SE-103 65 Stockholm, Sweden e-Mail eva.nyika@tandf.co.uk

Germany, Austria and Switzerland Gabriela Mauch Area Sales Manager

Taylor & Francis Group (Books Ltd)

Karlshofstr. 22 70599 Stuttgart, Germany Tel: +49 (0)711 7207231 Fax: +49 (0)711 7220668 Mobile +49 (0)173 9059469 e-mail: gabriela.mauch@tandf.co.uk

Spain, Portugal, Italy, and Greece Philip Veysey Area Sales Manager Príncipe de Vergara 109, 28002 Madrid, Spain Tel: +34 91 700 0688 Fax: +34 91 141 2304 Mobile: +34 68 777 3678 e-mail: philip.veysey@informa.com

Eastern Europe Marek Lewinson (Humanities and Social Sciences) Bohaterewicza 3/45 03-982 Warsaw, Poland Tel/fax: +48 (0) 22 6714819 Mobile: +48 (0) 602 707 037 e-mail: mlewinso@it.com.pl Radek Janousek (Science and Technology) Pod Nouzovem 972/21 197 00 Prague, Czech Republic Tel: +42 (0) 28 658 49888 Mobile: +42 (0) 602294014 e-mail: radek@mareklewinson.com

England and Wales London and Eastern England James Whittle Area Representative Mobile: 07802 536233 e-mail: james.whittle@tandf.co.uk

West Midlands, Southern England, the South West and South Wales John Blake Area Representative Mobile: 07889 263 857 e-mail: john.blake@tandf.co.uk

North and Northwest England, East Midlands and North Wales Lucy Pink Area Representative Mobile: 07860 633156 e-mail: lucy.pink@tandf.co.uk

North of England, Scotland, Ireland and Northern Ireland Nick Pepper Area Representative Mobile: 07825 748476 e-mail: nick.pepper@tandf.co.uk

Library Supply Nigel Berkeley Library Supply and London Key Accounts Manager Mobile: 07795 968206 e-mail: nigel.berkeley@tandf.co.uk

Online Retailers Rod Abraham Assistant UK Sales Manager Mobile: 07860 380 814 Fax: 01372 273 744 e-mail: rod.abraham@tandf.co.uk


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Environmental Science & Engineering

US: Catalog no. CATAGL • ISBN: 978-0-8493-3864-9

US: Catalog no. CATEVE • ISBN: 978-0-8493-3874-8

http://issuu.com/CRCPress/docs/annualcat_aglife_2013

http://issuu.com/CRCPress/docs/annualcat_envsci_eng_2013

Biomedical Sciences

Ergonomics & Human Factors, Industrial Engineering & Manufacturing

US: Catalog no. CATBMS • ISBN: 978-0-8493-3866-3 http://issuu.com/CRCPress/docs/annualcat_biomed_2013

• Information about ancillary materials for textbooks • Status of eBook availability

US: Catalog no. CATHFI • ISBN: 978-0-8493-3875-5 http://issuu.com/CRCPress/docs/annualcat_erg_indeng_man_2013

Business, Management, & Public Administration US: Catalog no. CATBMP • ISBN: 978-0-8493-9175-0 http://issuu.com/CRCPress/docs/annualcat_bus_pub_admin_2013

Chemistry & Chemical Engineering US: Catalog no. CATSPC • ISBN: 978-0-8493-3867-0 http://issuu.com/CRCPress/docs/annualcat_chem_chemeng_2013

Civil & Mechanical Engineering US: Catalog no. CATMCE • ISBN: 978-0-8493-3880-9 http://issuu.com/CRCPress/docs/annualcat_civil_mecheng_2013

Food Science & Nutrition US: Catalog no. CATFSN • ISBN: 978-0-8493-3876-2 http://issuu.com/CRCPress/docs/annualcat_foodsci_2013

Forensic Science, Law Enforcement, & Homeland Security US: Catalog no. CATFSC • ISBN: 978-0-8493-3877-9 http://issuu.com/CRCPress/docs/annualcat_foren_lawenf_homsec_2013

Mathematics & Statistics US: Catalog no. CATMTS • ISBN: 978-0-8493-3879-3

Computer Science, Information Technology, & Game Development

http://issuu.com/CRCPress/docs/annualcat_math_stats_2013

US: Catalog no. CATITB • ISBN: 978-0-8493-3878-6

US: Catalog no. CATMSN • ISBN: 978-0-8493-3885-4

http://issuu.com/CRCPress/docs/annualcat_compsci_it_gamedev_2013

Medicine http://issuu.com/CRCPress/docs/annualcat_med_2013

Electrical Engineering

Physics & Materials Science

US: Catalog no. CATEEC • ISBN: 978-0-8493-3869-4

US: Catalog no. CATPHY • ISBN: 978-0-8493-9176-7

http://issuu.com/CRCPress/docs/annualcat_eleceng_2013

http://issuu.com/CRCPress/docs/annualcat_physics_matsci_2013

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