Biomaterials and Medical Devices

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Contents Nanomaterials ............................................................3 Complex Tissue and Organs......................................10 Engineering Cells ......................................................12 Biotechnology............................................................14 Materials Science ......................................................18 Page 3

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Biomaterials Education ..............................................23 Industry Applications ................................................26 Forthcoming..............................................................29

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Nanomaterials New!

Nanobiomaterials Handbook Edited by

Balaji Sitharaman State University of New York at Stony Brook, USA

This volume provides a comprehensive overview of the field, offering a broad introduction for those new to the subject as well as a useful reference for advanced professionals. Analyzing major topics and disciplines in this arena, the book examines various synthesis and processing techniques important for developing nanobiomaterials, explores their unique nanoscopic physicochemical properties, discusses potential applications, and describes the interactions between bionanomaterials/biological systems and the biocompatibility issues associated with bionanomaterials. • Surveys the major topics and disciplines underlying the subject of nanobiomaterials • Examines state-of-the-art research and practice from around the world • Includes contributions by a team of world-renowned experts • Presents the unique challenges in the design, fabrication, and evaluation of bionanomaterials from a device-development and applications point of view • Explores the intersection of bionanomaterials with biological systems • Discusses issues related to the biocompatibility of bionanomaterials Selected Contents: Nanobiomaterials: Current and Future Prospects. Multifunctional Gold Nanoparticles for Cancer Therapy. Synthesis, Processing, and Characterization of Ceramic Nanobiomaterials for Biomedical Applications. Synthesis, Properties, Characterization, and Processing of Polymeric Nanobiomaterials for Biomedical Applications. Carbon-Based Nanomedicine. Synthetic and Toxicological Characteristics of Silica Nanomaterials for Imaging and Drug Delivery Applications. Peptide-Based SelfAssembled Nanofibers for Biomedical Applications. Electrostatically Self-Assembled Nanomaterials. … Catalog no. 94661, June 2011, 737 pp. ISBN: 978-1-4200-9466-4, $169.95 / £108.00 Also available as an eBook

Nanofabrication Handbook Edited by

Stefano Cabrini Lawrence Berkeley National Laboratory, California, USA

Satoshi Kawata Osaka University, Japan

“It is rich with illustrations and the authors of the individual chapters have made a real effort to introduce readers to the basic concepts in understandable terms while also capturing the current leading edge in their field. The amazing micrographs of prototype structures … offer an inspiring snapshot of the many and varied accomplishments of the researchers working in these technology development and application fields … a solid introduction to methods in current use in nanoscale research while the breadth of topics will also permit experienced practitioners to learn about methods and applications outside their own areas of experience.” —Donald Tennant, Cornell NanoScale Science and Technology Facility

“An impressive work covering all the important nanofabrication topics and contents … Highly recommended.” —Din Ping Tsai, National Taiwan University

• Introduces the central concepts of nanofabrication • Explains how to resolve problems that arise in the experimental phase • Covers a host of techniques, including electron beam lithography, focused ion beam, plasma-assisted pattern transfer, optical lithography, and soft x-ray lithography • Describes new and emerging methods, such as nanoimprint lithography, scanning probe lithography, two-photon lithography, self assembly, plasmonic nanolithography, and deterministic doping • Discusses how nanofabrication processes are used in NEMS, protein/cell analysis, photonics, and electronics Selected Contents: Standard Lithography. New Lithographic Techniques. Nanofabrication Applications.

Catalog no. 90526, March 2012, 546 pp. ISBN: 978-1-4200-9052-9, $129.95 / £82.00 Also available as an eBook

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Nanomaterials New Edition of a Bestseller!

Fundamentals of Microfabrication and Nanotechnology Third Edition (Three-Volume Set) Marc J. Madou University of California, Irvine, USA

Thoroughly revised and updated, this perennial bestseller lays the foundation for comprehensive theoretical and practical understanding of MEMS and NEMS. Expanded to three volumes to reflect the substantial growth in the field, this edition features recent developments in nano- and micromanufacturing techniques, DNA and protein arrays, fluidics, photonics, and actuators. Illustrated in color throughout, the text includes endof-chapter problems and worked-out examples, with many culled from recent literature and the author’s own work. Ancillaries are available upon qualifying course adoption.

“… easy to read, and I found some concepts explained in ways I hadn’t heard before … very informative, very good for teaching!” —Jorg P. Kutter, Technical University of Denmark

“… offers the widest and yet the most detailed coverage of all essential and fundamental aspects of microfabrication and nanotechnology. The author has done an excellent and remarkable job in synthesizing such diverse material under a single umbrella.” —Suman Chakraborty, IIT Kharagpur, India

“Once again, Professor Madou has made an incredible contribution to the MEMS/NEMS global community in writing this series of books.” —Nico de Rooij, Institute of Microengineering, EPFL

Catalog no. 3180, August 2011 1992 pp., ISBN: 978-0-8493-3180-0, $249.95 / £159.00

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Nanomaterials Also available as individual volumes Solid-State Physics, Fluidics, and Analytical Techniques in Micro- and Nanotechnology Selected Contents: Historical Note: The Ascent of Silicon, MEMS, and NEMS. Crystallography. Quantum Mechanics and the Band Theory of Solids. Silicon Single Crystal is Still King. Photonics. Fluidics. Electrochemical and Optical Analytical Techniques. Catalog no. 55119, July 2011 656 pp., ISBN: 978-1-4200-5511-5, $99.95 / £63.99 Also available as an eBook

Manufacturing Techniques for Microfabrication and Nanotechnology Selected Contents: LITHOGRAPHY: Photolithography. Next-Generation Lithographies and Lithography Research. PATTERN TRANSFER WITH SUBTRACTIVE TECHNIQUES: Dry Etching. Wet Chemical Etching and Wet Bulk Micromachining—Pools as Tools. Thermal Energy-Based Removing. Mechanical Energy-Based Removing. PATTERN TRANSFER WITH ADDITIVE TECHNIQUES: Physical and Chemical Vapor Deposition—Thin Film Properties and Surface Micromachining. Chemical, Photochemical and Electrochemical Forming Techniques. Thermal Energy-Based Forming Techniques—Thermoforming. Micro-Molding Techniques—LIGA. Catalog no. 55194, July 2011 670 pp., ISBN: 978-1-4200-5519-1, $99.95 / £63.99 Also available as an eBook

From MEMS to Bio-MEMS and Bio-NEMS Manufacturing Techniques and Applications Selected Contents: FROM TRADITIONAL MANUFACTURING TO NANOTECHNOLOGY: Nonlithography-Based (Traditional) and Lithography-Based (Nontraditional) Manufacturing Compared. Nature as an Engineering Guide Biomimetics. Nanotechnology: Top-Down and Bottom-Up Manufacturing Approaches Compared. Packaging, Assembly, and SelfAssembly. Selected Materials and Processes for MEMS and NEMS. Metrology and MEMS/NEMS Modeling. SCALING LAWS, ACTUATORS, AND POWER AND BRAINS IN MINIATURE DEVICES: Scaling Laws. Actuators. Power and Brains in Miniature Devices. MINIATURIZATION APPLICATION: MEMS and NEMS Applications. Catalog no. 5516X, July 2011 650 pp., ISBN: 978-1-4200-5516-0, $99.95 / £63.99 Also available as an eBook

Solutions manual, PowerPoint lecture slides, and electronic figures available upon qualifying course adoption.

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Nanomaterials Micro and Nano Techniques for the Handling of Biological Samples

New!

Simulations in Nanobiotechnology Edited by

Jaime Castillo-León, Winnie Edith Svendsen, and Maria Dimaki

Kilho Eom Korea University, Seoul, South Korea

Technical University of Denmark, Lyngby

The techniques and tools used to understand many biological problems must be able to handle biological material without damaging or altering its natural state. This book assesses various micro and nano techniques currently available to handle these materials. It shows how the techniques can effectively manipulate biological samples and highlights the advantages and shortcomings of each. The authors also help readers understand how the manipulation tools work and how to determine the appropriate tool for their needs. • Provides a comprehensive description of various techniques currently available for manipulating biological samples • Evaluates the advantages and limitations of each technique, helping readers to determine the appropriate tool for their needs and to understand how the manipulation tools work • Illustrates the use of the techniques in research and analytical laboratories Selected Contents: Interfacing Biological Material with Micro- and Nanodevices. Atomic Force Microscopy for Liquid Applications. Manipulation by Electrical Fields. Optical Manipulation Techniques. Ultrasonic Manipulation Techniques. 3D Biomanipulation Using Microgrippers. Magnetic Manipulation of Biological Structures. Microfluidic Manipulation of Biological Samples. Catalog no. K11354, August 2011, 255 pp. ISBN: 978-1-4398-2743-7, $129.95 / £82.00 Also available as an eBook

This book provides insights into computational simulations of biomolecules and nanomaterials collectively. It also examines the interactions between biomolecules and nanomaterials, such as DNA-wrapped nanotubes, nanobiosensors, and biomimetic materials. Expert contributors from around the world address the molecular dynamics of protein translocation, coarsegrained modeling of CNT-DNA interaction, multiscale modeling of nanowire resonator sensors, and the molecular dynamics simulation of protein mechanics. • Provides a quantitative understanding of the mechanical function of biological molecules and nanomaterials • Includes general computational schemes with various approaches from atomic simulations to continuum simulations • Addresses the theoretical/simulation side of nanobiotechnology and presents case studies Selected Contents: Molecular Dynamics of Protein Translocation. Coarse-Grained Modeling of DNA Translocation through Nanopore. Atomistic Simulation of Auger Process in Nanoparticle-Based Theragnostics. Coarse-Grained Modeling of CNTDNA Interaction. Molecular Dynamics of CNT-DNA Interaction. Modeling of CNT-DNA Hybrid Complex. Coarse-Grained Modeling of NanoCantilever-Based DNA Detection. Coarse-Grained Modeling of Micro- or Nano-Cantilever Sensors for Atomistic Detection. Continuum Modeling of CNTBased Molecular Recognitions. Multi-Scale Modeling of Nanowire Resonator Sensors. CauchyBorn Rule for Modeling Graphene Sheet. CoarseGrained Modeling of Single-Molecule Experiments. Coarse-Grained Modeling of Protein Dynamics. Molecular Dynamics Simulation of Protein Mechanics. Continuum Modeling of Large Protein Complex. Modeling of Biomimetic Adhesive.

Catalog no. K11581, October 2011, 562 pp. ISBN: 978-1-4398-3504-3, $139.95 / £89.00 ßAlso available as an eBook

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Nanomaterials Nanotechnology in Tissue Engineering and Regenerative Medicine

Nano- and Biocomposites Edited by

Alan Kin-tak Lau

Edited by

University of Southern Queensland, Australia, and The Hong Kong Polytechnic University, Kowloon

Ketul Popat

Farzana Hussain

Colorado State University, Fort Collins, USA

Bringing together an unparalleled field of experts, this volume explores various aspects of nanotechnology and its applications in biomedical fields. The book uses an application-oriented approach to relate laboratory-based research to the development of technologies and their adoption in an industry environment, focusing chiefly on drug delivery, tissue engineering, and regenerative medicine. • Provides comprehensive information about cutting-edge research in tissue engineering and regenerative medicine • Relates laboratory research to the development of technologies that can be readily adaptable to an industrial environment • Includes references in each chapter to enhance further study Selected Contents: Atomic Force Microscope

Oregon State University, Corvallis, USA

Khalid Lafdi University of Dayton, Ohio, USA

This forward-thinking book is one of the first to meld research in biocomposites with advances in nanocomposite technology to provide an interdisciplinary resource on advanced materials for the biomedical industry. It covers nanostructured polymer composites, nano/bio composites, developments in tissue engineering, safer resins for tooth and bone repair, and improved artificial joints, along with potential opportunities for continued research. • Focuses on adopting current technologies to solve emerging problems in the area of bionanotechnology • Covers nanostructured polymer composites • Includes both nano and biocomposite materials technologies for advanced structural engineering and tissue engineering • Addresses real-life applications in industry

Lithography on Biomimetic Surfaces. NanofiberBased Integrative Repair of Orthopedic Soft Tissues. Polycaprolactone Nanowires for Controlling Cell Behavior at the Biointerface. Electrospun Nanofibers for Neural Applications. Mixed Monolayer System of Mercaptobenzoic Acid and Polyethylene Glycol for pH Sensing: Surface-Enhanced Raman Scattering Studies. Nano-Enabled Platforms for Metastatic Malignant Melanoma. Immune Response to Implanted Nanostructured Materials. Enhanced Cell Growth, Function, and Differentiation by TiO2 Nanotube Surface Structuring. Electrospun Pseudo Poly (Amino Acids) for Tissue Engineering Applications. Nanotechnologies for Peripheral Nerve Regeneration. Nanoscale Control of Cell–Substrate Adhesion. Nanofibrous Materials for Vascular Tissue Engineering and Regeneration. Engineering Soft Nanostructures for Guided Cell Response. Nanoparticles-Incorporated Scaffolds for Tissue Engineering Applications. Index.

MER COMPOSITES: Carbon Nanotube Polymer Composites. Processing, Properties, and Flow Behavior of Carbon Nanofiber-Based Polymeric Nanocomposites. Rheology in Polymer/Clay Nanocomposites: Mesoscale Structure Development and Soft Glassy Dynamics. Polymer/Graphite Nanocomposites. Polymer Nanocomposite Flammability and Flame Retardancy. NANO-BIO COMPOSITES: AnimalBased Fiber-Reinforced Biocomposites. Biopolymeric Nanofibers for Tissue Engineering. Potential Use of Polyhydroxyalkanoate (PHA) for Biocomposite Development. The Reductionist Approach to the Molecular and Supramolecular Structures of Elastin. Elastin and Elastin-Based Polymers. PLA-Based Bioand Nanocomposites. Nanomaterials Formulation and Toxicity Impact. Index.

Catalog no. K10090, November 2010, 302 pp. ISBN: 978-1-4398-0141-3, $125.95 / £80.99

Catalog no. 8027X, August 2009, 408 pp. ISBN: 978-1-4200-8027-8, $174.95 / £112.00

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Selected Contents: NANOSTRUCTURED POLY-

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Nanomaterials Nanotechnology and Tissue Engineering

Bionanotechnology II

The Scaffold

Global Prospects

Edited by

Edited by

Cato T. Laurencin

David E. Reisner

University of Virginia, Charlottesville, USA

The Nano Group, Inc., Farmington, Connecticut, USA

Lakshmi S. Nair

Reflecting the increasing importance of nanomedicine and biotechnology, this book covers biomimicry, stem cells, optical togs, and nanocoatings for medical implantable devices. Experts from Iran, Cuba, South Africa, United Kingdom, Canada, China, India, and Russia provide insights into the food and cosmetics industries as well as cardiac diagnosis, batteries, drug delivery, photonics, and DNA building blocks. They also discuss protein devices, quantum dots, bioanalysis, optics, nanomedicine, personalized medicine, and the business of emerging bionanotech companies. Catalog no. K10254, August 2011, 583 pp. ISBN: 978-1-4398-0463-6, $99.95 / £63.99 Also available as an eBook

University of Connecticut, Farmington, USA

With chapters written by world-famous researchers involved with various facets of nanostructured scaffolds, this is the first resource that brings together research and background information on a complete range of engineering processes that have led to the development of a number of highly useful tissues. It details the fundamental and advanced aspects of nanofabrication and includes an examination of cellular interactions at the nanoscale level. The book also discusses clinical implications and applications. Catalog no. 51822, June 2008, 384 pp. ISBN: 978-1-4200-5182-7, $169.95 / £108.00 Also available as an eBook

New!

Coming soon!

Self-Healing at the Nanoscale

Bionanomaterials for Dental Applications

Mechanisms and Key Concepts of Natural and Artificial Systems

Edited by

Mieczyslaw Jurczyk

Edited by

Poznan University of Technology, Poland

Vincenzo Amendola and Moreno Meneghetti Self-healing materials can repair damage caused by their activity, similar to how biological systems heal themselves after being wounded. This book presents a general strategy and key concepts of self-healing systems, repairing mechanisms at the nanoscale, and the role of nanostructures in these systems. The text covers natural and artificial systems, including nanostructured and macroscopic systems. It also reviews a series of systems that show potential for building self-healing devices.

Recently, chemical, physical, and mechanical processes for the fabrication of metal/alloyceramic nanocomposites with a unique microstructure have been developed. This book presents information about the structure and characteristics of new dental nanomaterials, corrosion behavior of metallic biomaterials and implants, as well as methods of surface improvement of implants by means of nanoengineering, which decides the biocompatibility of the insert. The text thoroughly explains the osseointegration from a biological viewpoint and early tissue response.

Catalog no. K12542, December 2011, 463 pp. ISBN: 978-1-4398-5473-0, $129.95 / £82.00

Catalog no. N10474, May 2012, c. 350 pp. ISBN: 978-981-4303-83-5, $149.95 / £95.00

Università di Padova, Italy

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Nanomaterials New!

Handbook of Harnessing Biomaterials in Nanomedicine Preparation, Toxicity, and Applications Edited by

Dan Peer Tel Aviv University, Israel

This book presents the theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications. It examines the use of nano-proteins, such as antibodies and peptides, as targeting agents for therapeutics and diagnosis and the use of nanocarrier-based biomaterials for the manipulation of stem cells. It also explores different aspects of toxicity of nanocarriers, including the immune response and liver toxicity, and success stories of biomaterials that have reached the clinics. Catalog no. N10498, January 2012, 424 pp. ISBN: 978-981-4316-46-0, $149.95 / £95.00

Nanocomposite Particles for Bio-Applications Materials and BioInterfaces Edited by

Tito Trindade and Ana Luisa Daniel da Silva Universidade de Aveiro, Portugal

This book provides a concise state of the art of the synthesis and properties of nanocomposite particles with interest for diverse bio-applications. Contributions are mainly related to the chemical design of nanocomposite particles, their properties and constituent materials, and the tailoring of bio-interfaces that may be relevant to the fields of clinical diagnosis and drug delivery procedures. The text includes many figures and a good survey of references that accompany each chapter. Catalog no. N10427, August 2011, 312 pp. ISBN: 978-981-4267-78-6, $149.95 / £95.00 Also available as an eBook

Also available as an eBook

Viral Nanoparticles Tools for Material Science and Biomedicine

Carbon Nanotubes

Edited by

From Bench Chemistry to Promising Biomedical Applications

Nicole F. Steinmetz

Edited by

Case Western Reserve University, Cleveland, Ohio, USA

Giorgia Pastorin

Marianne Manchester University of California, San Diego, La Jolla, USA

This work presents the applications of viral nanoparticles (VNPs) in areas ranging from materials science to biomedicine. It summarizes the many different VNP building blocks and describes chemistries that allow one to attach, entrap, or display functionalities on VNPs. The book outlines the strategies for the construction of 1-, 2-, and 3-D arrays; highlights the achievements in using VNPs as tools for novel biosensors and nanoelectronic devices; and describes efforts in designing VNPs for biomedical applications.

National University of Singapore

“This unique book comes at the right time when the scientific community and numerous organizations are divided on the potential applicability of carbon nanotubes. A concentrate of the most recent scientific discoveries written by highly recognized authors in the field. An excellent reference for inspiring scientists and students.” —Sylviane Muller, CNRS, France

Catalog no. N10419, January 2011, 156 pp. ISBN: 978-981-4241-68-7, $129.95 / £82.00 Also available as an eBook

Catalog no. N10424, August 2011, 284 pp. ISBN: 978-981-4267-45-8, $149.95 / £95.00 Also available as an eBook

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Nanomaterials / Complex Tissue and Organs Coming soon!

With Biological Applications

Polymers for Vascular and Urogenital Applications

Edited by

Edited by

Michelle L. Oyen

Shalaby W. Shalaby

University of Cambridge, UK

Poly-Med Inc., Anderson, South Carolina, USA

Handbook of Nanoindentation

“Michelle Oyen has done a superb job compiling experts in the field of nanoindentation. This book spans a wide variety of topics ranging from the fundamental theory and instrumentation of nanoindentation to its application in biological materials including soft tissues, mineralized tissues, and cell structures. This book is an excellent resource for students and researchers alike.” —Lisa Pruitt, University of California, Berkeley

Catalog no. N10404, October 2010, 358 pp. ISBN: 978-981-4241-89-2, $149.95 / £95.00 Also available as an eBook

Handbook of Materials for Nanomedicine Edited by

Vladimir Torchilin and Mansoor M. Amiji Northeastern University, Boston, Massachusetts, USA

The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover major information about these materials, both on experimental levels and already applied in patients. The book covers organic and polymeric nanostructures, dendrimer-based nanomaterials, lipid-based structures, polymeric amphiphiles, inorganic nanostructures, silicabased gold nanoshells, metal oxide nanoarchitectures, fluorescent quantum dots, and lipid coated microbubbles and nanodroplets.

Karen J.L. Burg Clemson University, South Carolina, USA

Waleed Shalaby Chadds Ford, Pennsylvania, USA

This book covers attributes of polymers used for vascular, urological, and gynecological materials. It provides a brief analysis of how the use of polymers in vascular and urogenital applications has evolved in the past five decades and outlines their common and specific functional requirements. The book features small, readable monographs that provide a brief description of the evolving role of a particular material and discuss materials processing and in vitro and in vivo evaluation, complete with case studies. • Provides contributions from authors representing a diverse technical group of clinicians with strong science or engineering backgrounds and research interests • Supplies a comprehensive link between polymeric biomaterials and their application in the urinogenital area • Describes the evolving role of a particular family of materials • Discusses recent developments in applications and the rationale for present and future clinical significance Selected Contents: History and Evolution of Synthetic Vascular and Urinogenital Materials. Common and Specific Functional Requirements for Vascular and Urinogenital Applications. Polymers for Specific Devices for Vascular Applications. Polymers for Specific Urinogenital Applications. Polymers for Devices for Common Use in Vascular and Urinogenital Applications.

Catalog no. 76949, April 2012, c. 268 pp. ISBN: 978-1-4200-7694-3, $179.95 / £114.00 Also available as an eBook

Catalog no. N10412, September 2010, 868 pp. ISBN: 978-981-4267-55-7, $399.95 / £254.00 Also available as an eBook

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Complex Tissue and Organs Tissue Engineering

Rice University, Houston, Texas, USA

Regenerative Medicine and Biomaterials for the Repair of Connective Tissues

Joseph D. Bronzino

Edited by

Trinity College, Hartford, Connecticut, USA

C. Archer and J. Ralphs

John P. Fisher University of Maryland, College Park, USA

Antonios G. Mikos

Bringing together a diverse group of international contributors with backgrounds in academia, clinical medicine, and industry, this volume surveys advances in this relatively young area. Divided into three sections, it discusses the fundamental concepts of tissue engineering, enabling technologies, and tissue engineering applications. The book also examines strategies that incorporate scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques that are being applied in regenerative medicine. Catalog no. 9026, May 2007, 600 pp. ISBN: 978-0-8493-9026-5, $104.95 / £66.99

Cardiff University, UK

The biomaterials and biomechanics for soft tissue repair have been underrepresented in the past; in particular, the natural connection between cartilage, tendons, and ligaments is often not made. This book addresses the gap by exploring the natural association of cartilage, tendons, and ligaments. It reviews the different structures and biomechanics and discusses practical techniques and biomaterials that are being used to repair connective tissues. Catalog no. N10011, February 2010, 600 pp. ISBN: 978-1-4398-0110-9, $249.95 / £159.00

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New!

Handbook of Intelligent Scaffold for Tissue Engineering and Regenerative Medicine Edited by

Gilson Khang Chonbuk National University, Jeonju, North Korea

Providing detailed knowledge about fullerene nanowhiskers and the related low-dimensional fullerene nanomaterials, this book introduces tubular nanofibers made of fullerenes, “fullerene nanotubes,” as well as the single crystalline thin film made of C60, called “fullerene nanosheet.” It demonstrates the synthetic method (liquid–liquid interfacial precipitation method); covers physical and chemical properties, such as electrical, mechanical, optical, magnetic, thermodynamic, and surface properties; and explores the application of fullerene nanowhiskers in electronic devices. Catalog no. N10464, February 2012, 974 pp. ISBN: 978-981-4267-85-4, $499.95 / £318.00 Also available as an eBook

Biointegration of Medical Implant Materials Science and Design Edited by

C.P. Sharma Sree Chitra Tirunal Institute for Medical Sciences and Technology, India

This volume explores recent research into material and tissue interaction and integration. The first section discusses the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. The second part reviews techniques in drug delivery, including inorganic nanoparticles for targeted drug delivery and alginate-based drug delivery devices. The third section covers the biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long-term use, and rapid prototyping in biomedical engineering. Catalog no. N10181, August 2010, 384 pp. ISBN: 978-1-4398-3064-2, $229.95 / £146.00

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Engineering Cells Coming soon!

Edited by

Biomaterials and Stem Cells in Regenerative Medicine

Jiro Nagatomi

Edited by

Clemson University, South Carolina, USA

Murugan Ramalingam

This handbook not only presents cutting-edge research findings across various fields and organ systems, but also provides elementary chapters on mechanics and molecular analysis techniques to encourage cross-field understanding and appropriate planning.

Seeram Ramakrishna

Mechanobiology Handbook

University of Strasbourg, France

Aided by the continuous advancement of research tools in both mechanics and biology, more sophisticated experiments and analyses are possible—thus fueling the growth of the field of mechanobiology. Considering the complexity of the mechanics and the biology of the human body, most of the world of biomechanics remains to be studied. Since the field is still developing, the Mechanobiology Handbook does not force one unified theory, but brings out many different viewpoints and approaches to stimulate further research questions. • Presents research data and viewpoints from diverse fields of mechanobiology • Includes background information in mechanics and cell biology • Explores application areas such as tissue engineering • Contains references at the end of each chapter to facilitate further study Selected Contents: Basic Science Tools for Mechanobiology Research. Literature Review of Mechanobiology: Research Findings and Theories. Cardiovascular Systems. Musculoskeletal Systems. Other Organ Systems. Frontiers of Mechanobiology. Index. Catalog no. 91212, March 2011, 563 pp. ISBN: 978-1-4200-9121-2, $169.95 / £109.00 Also available as an eBook

National University of Singapore

Serena Best University of Cambridge, UK

This book bridges the gap in experimental approaches and understanding among the key areas of biomedical research. It provides important aspects dealing with the basic science involved in structure and properties, techniques and technological innovations in processing and characterizations, and applications of biomaterials and stem cells in tissue regeneration. Coverage ranges from fundamental principles to current technological advancements at the macro/micro/nano/molecular scales. • Provides a self-contained resource for understanding the current perspectives on biomaterials and stem cells in regenerative medicine • Offers extensive coverage of a range of biomaterials and their interaction with stem cells and other cellular elements • Covers different length scales, including micro and nano levels • Supplies an integrated approach to the organization of materials science and engineering, micro/nanotechnology, bioengineering, and biomedical sciences • Incorporates useful figures and tables with current data Selected Contents: Identification and Application of Polymers as Biomaterials for Tissue Engineering and Regenerative Medicine. Hydrogel as Stem Cell Niche for In Vivo Applications in Regenerative Medicine. Fabrication and Application of Gradient Hydrogels in Cell and Tissue Engineering. Smart Biomaterial Scaffold For In Situ Tissue Regeneration. Fabrication of 3D Scaffolds and Organ Printing for Tissue Regeneration. Natural Membranes as Scaffold for Biocompatible Aortic Valve Leaflets. …

Catalog no. K13711, June 2012, c. 608 pp. ISBN: 978-1-4398-7925-2, $149.95 / £95.00 Also available as an eBook

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Engineering Cells New!

Stem Cells and Revascularization Therapies Edited by

Hyunjoon Kong University of Illinois at UrbanaChampaign, USA

Gene and Cell Therapy Therapeutic Mechanisms and Strategies, Third Edition Edited by

Nancy Smyth Templeton

Andrew J. Putnam

Gradalis Inc., Carrollton, Texas, USA

University of California, Irvine, USA

The latest edition of Gene and Cell Therapy provides comprehensive coverage of all aspects of the tools and technologies that are currently available in the field. This third edition features 12 additional chapters that address gene and cell therapies for diabetes and cardiovascular disease, relevant nanotechnologies, siRNA therapeutics, dendrimers, clinical trials, human embryonic stem cell research, tissue engineering, and novel polymers. All chapters in the text have been substantially updated and revised to reflect the current information in the field.

Lawrence B. Schook University of Illinois at Urbana-Champaign, USA

In the last few decades, significant advancements in the biology and engineering of stem cells have enabled progress in their clinical application to revascularization therapies. Some strategies involve the mobilization of endogenous stem cell populations and others employ cell transplantation. This book focuses on the fundamentals and applied studies in stem cell biology and provides perspectives associated with the development of revascularization strategies. Catalog no. K10180, December 2011, 342 pp. ISBN: 978-1-4398-0323-3, $149.95 / £95.00

Catalog no. 8768, October 2008, 1120 pp. ISBN: 978-0-8493-8768-5, $259.95 / £165.00 Also available as an eBook

Also available as an eBook

Coming soon!

Cellular Response to Biomaterials

Regenerative Medicine, Stem Cells and the Liver

Edited by

Edited by

L. Di Silvio

David C. Hay

Kings College London, UK

MRC Centre for Regenerative Medicine, University of Edinburgh, Scotland

Examining the response of cells to a wide range of biomaterials with specific medical applications, this volume considers cell responses to a variety of polymers and ceramics and discusses degradable polymers and biocompatibility. It looks at cell responses and regenerative medicine, including vascular grafts, nerve repair, and Bioglass®, and explores the effect of surfaces and proteins on cell response. The book also reviews nano-engineered surfaces, the influence of plasma proteins on bone cell adhesion, and surface modification of titanium implants. Catalog no. WP9373, January 2009, 500 pp. ISBN: 978-1-4200-9373-5, $289.95 / £153.00

Researchers have been working to find solutions to cure failing human liver function. Given the ability of stem cells to self-renew and differentiate into specialized cell liver types, they represent an attractive strategy to replace lost liver function. This book collates recent research in this field. It outlines the complex nature of human liver disease and examines the potential that stem cell-based approaches have to offer. Catalog no. N10558, May 2012, c. 200 pp. ISBN: 978-1-57808-739-6, $99.95 / £63.99 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

13


Biotechnology

Buy the set & save

Biological and Biomedical Coatings Handbook Two-Volume Set Edited by

Sam Zhang Nanyang Technological University, Singapore

Important in today’s nanotechnology, biological and biomedical coatings have been studied extensively and are receiving much attention from researchers. A timely reference for experts and newcomers, this handbook explores the latest developments in films and coatings for biological and biomedical applications. The book covers a wide array of material types, including sol-gel, bio-ceramics, polymers, glass, nanomaterials, and chitosan. It also addresses various processes for developing and implementing these coatings, including CVD and PVD, drug delivery, released-control coatings, and spectroscopy. • Covers processing, properties, and performance • Discusses sol-gels, bio-ceramics, polymers, glasses, nanomaterials, and other materials • Explores CVD and PVD • Includes information on drug delivery and released-control coatings • Presents cutting-edge developments from world leaders in films and coatings research • Serves as a simplified introductory stepping stone for new entrants to the field • Gives experts up-to-date figures, tables, plots, and images to aid their own work Catalog no. K11126, May 2011, 976 pp. ISBN: 978-1-4398-2125-1, $249.95 / £159.00 Also available as an eBook

Also available as individual volumes

Processing and Characterization

Applications

Selected Contents: Bonelike Mineral and

Selected Contents: Sol-Gel Derived

Organically Modified Bonelike Mineral Coatings. Synthesis and Characterization of Hydroxyapatite Nanocoatings by Sol–Gel Method for Clinical Applications. Hydroxyapatite and Other Biomedical Coatings by Electrophoretic Deposition. Thermal Sprayed Bioceramic Coatings: Nanostructured Hydroxyapatite (HA) and HA-Based Composites. Nanostructured Titania Coatings for Biological Applications: Fabrication and Characterization. Hydrothermal Crystallization with Microstructural SelfHealing Effect on Mechanical and Failure Behaviors of Plasma-Sprayed Hydroxyapatite Coatings. Bioceramic Coating on Titanium by Physical and Chemical Vapor Deposition. Coating of Material Surfaces with Layerby- Layer Assembled Polyelectrolyte Films. Bioactive Glass-Based Coatings and Modified Surfaces: Strategies for the Manufacture, Testing, and Clinical Applications for Regenerative Medicine.

Hydroxyapatite Coatings on Metallic Implants: Characterization, In Vitro and In Vivo Analysis.Amorphous Carbon Coatings for Biological Applications. Biomedical Applications of CarbonBased Materials. Impedance Spectroscopy on Carbon-Based Materials for Biological Application. Control of Drug Release from Coatings: Theories and Methodologies. Release-Controlled Coatings. Orthopedic and Dental Implant Surfaces and Coatings. Piezoelectric Zinc Oxide and Aluminum Nitride Films for Microfluidic and Biosensing Applications. Medical Applications of SputterDeposited Shape Memory Alloy Thin Films. Bioactive Coatings for Implanted Devices.

Catalog no. K12269, May 2011, 456 pp. ISBN: 978-1-4398-4995-8, $139.95 / £89.00

Catalog no. K12270, May 2011, 520 pp. ISBN: 978-1-4398-4996-5, $139.95 / £89.00 Also available as an eBook

Also available as an eBook

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Biotechnology New!

OMICS Biomedical Perspectives and Applications

Healthcare Biotechnology

Edited by

A Practical Guide

Debmalya Barh

Dimitris Dogramatzis

Institute of Integrative Omics and Applied Biotechnology, West Bengal, India

Dogramatzis Pharmacy, Athens, Greece

Kenneth Blum and Margaret Anne Madigan

“The section on marketing is also particularly strong and well thought through. … provides insight into the biotechnology business sector.”

LifeGen, San Diego, California, USA

“… this book will be intensively useful to scientists from both academia and industry, teachers and professors, health professionals, and mostly students, who should be encouraged to study and learn from its wisdom.” —Debasis Bagchi, University of Houston College of Pharmacy

A reflection of the explosion of research and development in this field, this book explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. It collates recent developments in the field into a state-of-the-art framework for this discipline. A select panel of experts discusses their cuttingedge omics research and novel technologies, supplying a basic platform of methods and applications as well as a multi-omics approach to future endeavors in the fertile areas of omics research. • Provides technical background for omics fields, including bioinformatics, nutrigenomics, toxicology, stem cell research, magnetic nanoparticles, high-throughput screening, and safety in diagnostic imaging • Includes omics research in genetics and immunology • Discusses computational and systems biology • Focuses on the application of specific omics technologies to the discovery of omicsbased diagnostic and therapeutic modalities for disease treatment • Highlights the exponential growth in omics based on bioinformatics and other biotechnologies Selected Contents: Methodology and Application. Empirical Research. Computational and Systems Biology. Therapeutics. Future Perspective.

—British Journal of Biomedical Science

This guide focuses on the management of healthcare-related biotech, from conception through the product’s regulatory approval and entire life cycle. The book provides a practical, applicable resource to assist all health-care related biotech professionals in their day-to-day activities from the lab to the boardroom. It offers a comparison with the pharmaceutical industry, covers intellectual property protection and management, examines R&D and biomanufacturing, explores clinical trial design and regulations, and includes tips on running the business. • Offers a practical, step-by-step guide for both graduate students and industry professionals • Provides end-of-chapter problems and appropriate essays for each subject covered • Includes many illustrations and tables • Contains extensive references at the end of each chapter • Presents a business plan outline Selected Contents: THE HEALTHCARE BIOTECHNOLOGY INDUSTRY: Bioeconomy. INTELLECTUAL PROPERTY: Intellectual Property Management. Biolicensing. FUNDING: Biofinance. Biopartnering. NEW PRODUCT DEVELOPMENT: Biodrug Research. Biomanufacturing. MARKETING: Biomarketing Planning. Biopromotion. Biopricing. Biosupply Chain. Product Life Cycle Management. RUNNING THE BUSINESS: Biobusiness Models. Biosimilars Model. Biocompany Life Cycle.

Catalog no. K12108, December 2010, 689 pp. ISBN: 978-1-4398-4746-6, $104.95 / £66.99 Also available as an eBook

Catalog no. K12277, November 2011, 613 pp., ISBN: 978-1-4398-5008-4, $139.95 / £89.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Biotechnology

Porous Media

Biotechnology Operations

Applications in Biological Systems and Biotechnology

Principles and Practices

Edited by

Michael J. Roy

Kambiz Vafai

University of Wisconsin, Madison, USA

University of California, Riverside, USA

Applying the author’s experience teaching the subject and working in industry and government, this book introduces key biotechnology developments and covers critical elements, such as project management, regulatory affairs, quality assurance, biomanufacturing, quality control, nonclinical safety testing, and clinical evaluation. The author discusses these subjects in relation to development planning, process and pathways, management of integrated projects, and the business and economic aspects of development. Using simple language and explanatory figures, the text describes the functional areas that must be successfully integrated to safely and efficiently bring a biotechnology product to market. • Provides an introduction to each key biotechnology development subject, all compiled in one volume • Incorporates an integrated approach, tying together the seven key functional areas • Emphasizes the need to both plan and integrate an operations program, supplying the information required to successfully lead such efforts • Uses relatively simple language, clarifies jargon, and uses diagrams to describe processes, making concepts easy to understand

Presenting state-of-the-art research advancements, this volume explores innovative approaches to effectively apply existing porous media technologies to biomedical applications. World-class scientists and engineers cover various transport processes, mechanical behavior, and material properties of biological tissues from a porous media point of view. They also present pertinent aspects of experimental work and numerical techniques. • Explores state-of-the-art research advances related to the applications of porous media in biological systems and biotechnology • Covers various transport processes, mechanical behavior, and material properties of biological tissues from a porous media point of view • Presents experimental work and numerical techniques • Discusses the modeling of several phenomena, including flow changes in cerebral aneurysms, biomass growth, marine systems, and tissue homeostasis and repair

Selected Contents: Introduction to Biotechnology Operations: Planning for Success. Project Management. Regulatory Affairs. Regulatory Compliance. Quality Systems. Biomanufacture. Quality Control. Nonclinical Studies. Clinical Trials. Glossary. Additional Reading. Practical Problems and Questions. Catalog no. K11486, March 2011, 416 pp. ISBN: 978-1-4398-3027-7, $99.95 / £63.99

Selected Contents: A General Set of Bioheat Equations Based on the Volume Averaging Theory. Mathematical Models of Mass Transfer in Tissue for Molecular Medicine with Reversible Electroporation. Hydrodynamics in Porous Media with Applications to Tissue Engineering. Biomedical Implications of the Porosity of Microbial Biofilms. Influence of Biofilms on Porous Media Hydrodynamics. Using Porous Media Theory to Determine the Coil Volume Needed to Arrest Flow in Brain Aneurysms. Lagrangian Particle Methods for Biological Systems. …

Catalog no. 65416, August 2010, 632 pp. ISBN: 978-1-4200-6541-1, $149.95 / £95.00 Also available as an eBook

Also available as an eBook

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Biotechnology Transdermal and Intradermal Delivery of Therapeutic Agents

Macroporous Polymers

Application of Physical Technologies

Bo Mattiasson

Production Properties and Biotechnological/ Biomedical Applications Edited by Lund University, Sweden

Ajay K Banga

Ashok Kumar

Mercer University, Atlanta, Georgia, USA

Indian Institute of Technology, Kampur, India

Transdermal delivery is an important part of drug delivery systems and the use of physical enhancement methods to penetrate the skin barrier is where the field is headed. This book reviews the strategies available for the delivery of compounds into and through the skin. It also focuses on technological developments in the domain of nanotechnology that can be exploited to enhance the transdermal delivery of drugs.

Lund University, Sweden

Catalog no. K10285, May 2011, 309 pp. ISBN: 978-1-4398-0509-1, $129.95 / £82.00 Also available as an eBook

Igor Yu. Galeaev Presented in a systematic way, this book addresses the production, characterization, and application of macroporous polymers. The text considers traditional production methods, including phase separation polymerication, leaching, foaming, and double emulsion, as well as emerging ones, such as cryogelation. The chapters also discuss various applications of macroporous gels for the separation of biomolecules and for the cultivation of mammalian cells in bioreactors and tissue engineering. Catalog no. 84615, December 2009, 525 pp. ISBN: 978-1-4200-8461-0, $139.95 / £89.00 Also available as an eBook

Colloids in Drug Delivery Edited by

Drug Device Combination Products Delivery Technologies and Applications

Monzer Fanun

Edited by

Al-Quds University, East Jerusalem, Israel

A. Lewis Biocompatibles, UK

Colloidal systems have the potential to increase the shelf life and improve efficacy of a drug, thus reducing the required dosage concentrations and the frequency of administration. In this book, an international panel of scientists and researchers presents recent findings on the application of colloidal properties in drug delivery systems. The book promotes the understanding and improved design of novel and advanced drug delivery applications.

Drug delivery systems represent a vast area of research and development within biomaterials and medicine and the demand for sophisticated drug delivery devices continues to drive novel product development. Illustrating how effective drug delivery can be achieved by means other than oral tablets, this book provides a thorough analysis of the fundamentals, applications, and technologies of drug-device combination products for use throughout the human body. The book includes background information, areas of application, and the development of drug device combination products.

Catalog no. K10958, March 2010, 652 pp. ISBN: 978-1-4398-1825-1, $169.95 / £108.00 Also available as an eBook

Catalog no. N10136, January 2010 ISBN: 978-1-4398-2479-5, $244.99 / £155.00 For more information and complete contents, visit www.crcpress.com

17


Materials Science New!

Coming soon!

Materials in Biology and Medicine

Biomaterials Science An Integrated Clinical and Engineering Approach

Edited by

Sunggyu Lee Ohio University, Athens, USA

Edited by

David Henthorn

Yitzhak Rosen

St. Louis University, Missouri, USA

Superior NanoBioSystems, Washington, D.C., USA

With peer-reviewed chapters written by a select group of academic and industry experts, this comprehensive yet accessible book covers the most advanced materials used in biology and medicine. The book focuses on biomaterials and bioinspired materials, functional and responsive materials, controlling biology with materials, and the development of devices and enabling technologies. It will help readers tackle challenges of novel materials, carry out new process and product development projects, and create new methodologies for applications that enhance the quality of life. • Illustrates the emerging technological advances in the field • Provides the necessary scientific background of all application areas covered • Explains the technological details underlying the applications • Promotes novel process and product development efforts using green chemistry and engineering • Emphasizes the enhancement and modifications of the functionality of materials Selected Contents: Introduction: Materials in Biology and Medicine. Biomaterials. Hydrophilic Polymers for Biomedical Applications. Hydrogels. Polyanhydrides. Functional Biomaterials. Molecularly Imprinted Polymers. Functionalization of Carbon Nanotubes. Animal Cell Culture. Tissue Engineering. Bioactive Devices. Cell Encapsulation. BioMEMS. Immobilized Enzyme Technology. Biocompatibility-Imparting Nanofilm Coating. Catalog no. K13848, March 2012, 260 pp. ISBN: 978-1-4398-8169-9, $169.95 / £108.00 Also available as an eBook

Noel Elman Cambridge, Massachusetts, USA

Rather than approach biomaterials science from just a materials science and engineering perspective, this book also covers the clinical side. The book engages biomaterials engineers and physicians in a much-needed discussion that integrates both fields at many levels to increase the rate of successful deployment of biomaterials, lower the side effects of such a deployment, and accumulate knowledge for improving current methodologies and meeting future challenges. Leading contributors address hemocompatibility, carcinogenesis, infections, cellular mechanisms, signal transduction, clinical trials, MEMS, nanotechnology, FDA regulations, and ethical issues. • Discusses hemocompatibility • Covers biomaterials and carcinogenesis and infections • Includes coverage of clinical trials of biomaterial designs • Details the implementation of nanotechnology and MEMs in biomaterials • Addresses ethical issues and FDA standards Selected Contents: Overview. Hemocompatibility. Biomaterials and Carcinogenesis. Biomaterials and Infections. Cellular Mechanisms, Signal Transduction and the Development of New Biomaterials. Clinical Trials of Biomaterials: Design and Objectives. Tissue Engineering. Nanotechnology, MEMS, and Biomaterials: Making Them Work Together. Biomaterials: Setting the Standards and the FDA. Ethical Issues. Summary.

Catalog no. K10223, May 2012, c. 328 pp. ISBN: 978-1-4398-0404-9, $149.95 / £95.00 Also available as an eBook

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Materials Science New! New!

Biomimetics Nature-Based Innovation Yoseph Bar-Cohen JPL/Caltech, Pasadena, California, USA

A review of the current state of the art of biomimetics, this book documents key biological solutions that provide a model for innovations in engineering and science. Leading experts explore a wide range of topics, including artificial senses and organs; mimicry at the cell–materials interface; modeling of plant cell wall architecture; biomimetic composites; artificial muscles; biomimetic optics; and the mimicking of birds, insects, and marine biology. The book also discusses applications of biomimetics in manufacturing, products, medicine, and robotics; biologically inspired design as a tool for interdisciplinary education; and the biomimetic process in artistic creation. • Explores a wide range of topics from artificial senses and muscles to biomimetics in manufacturing, medicine, and robotics • Outlines the challenges to biomimetic-related innovation and offers a vision for the future • Addresses gaps in the current literature • Provides extensive end-of-chapter references for further reading Selected Contents: Introduction: Nature as a Source for Inspiration of Innovation. Artificial Senses and Organs—Natural Mechanisms and Biomimetic Devices. Biomimicry at the Cell–Material Interface. Multiscale Modeling of Plant Cell Wall Architecture and Tissue Mechanics for Biomimetic Applications. Biomimetic Composites. Electroactive Polymer Actuators as Artificial Muscles. Refreshable Braille Displays Actuated by Electroactive Polymers. Biological Optics. Biomimicry of the Ultimate Optical Device—The Plant. … Catalog no. K11566, September 2011, 788 pp. ISBN: 978-1-4398-3476-3, $159.95 / £99.00

Materials Science of DNA Edited by

Jung-II Jin Korea University, Seoul, South Korea

James Grote AFRL/RXPS, Wright Patterson Air Force Base, Ohio, USA

As interest continues to grow, DNA is expected to become central to nanobiotechnology because of its structural and chemical characteristics. With chapters written by experts in their respective fields, this text chiefly focuses on the rapidly growing fields of nanoscience, nanotechnology, and biotechnology. It is the first to address the materials science facet of DNA, rather than its chemical, biochemical, or biological aspects. The book includes tables, graphs, equations, and a CD-ROM to provide an understanding of DNA and the great potential of this biopolymer as advanced material. • Focuses on the materials science of DNA rather than on chemical, biochemical, or biological aspects • Provides a comprehensive description of DNA and the high potential of this biopolymer as an advanced material • Includes an eight-page color insert Selected Contents: Materials Science of DNA: An Introduction. Nanostructures and Nanomaterials via DNA-Based Self-Assembly. Intercalation of Organic Ligands as a Tool to Modify the Properties of DNA. DNA and Carbon-Based Nanomaterials: Preparation and Properties of Their Composites. Electrical and Magnetic Properties of DNA. DNA Ionic Liquid. DNA-Surfactant Thin-Film Processing and Characterization. Applications of DNA to Photonics and Biomedicals. DNA-Based Thin-Film Devices. Nucleic Acids-Based Biosensors. Materials Science of DNA—Conclusions and Perspectives.

Catalog no. K11352, December 2011, 338 pp. ISBN: 978-1-4398-2741-3, $119.95 / £76.99 Also available as an eBook

Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Materials Science Chitosan-Based Hydrogels

New!

Polyurethane Shape Memory Polymers

Functions and Applications Edited by

W.M. Huang

Kangde Yao, Junjie Li, Fanglian Yao, and Yuji Yin

Nanyang Techological University, Singapore

Bin Yang

Tianjin University, People's Republic of China

Helvoet Rubber & Plastic Technologies Pte Ltd., Singapore

This work details the latest progress in the research and development of chitosan-based biomaterials, providing the foundation for future research. The book introduces the formation and chemical structure of chitosan-based hydrogels. It also discusses the relationship between their structure and functions, which provides a theoretical basis for the design of biomaterials. In addition, many real-world examples illustrate the potential application of chitosan-based hydrogels in various fields, including materials science, biotechnology, pharmaceuticals, regenerative medicine, and cell engineering. • Presents the latest developments and real-world examples of chitosan-based hydrogels • Describes their formation and chemical structure • Highlights the relationship between their structure and functions • Discusses the application of chitosan-based hydrogels in drug release systems, tissue engineering, and pharmaceuticals • Chronicles the development of chitin and chitosan

Yong Qing Fu

Selected Contents: From Chitin to Chitosan.

of Polyurethane Shape Memory Polymer. Effects of Moisture on Glass Transition Temperature and Applications. Electrically Conductive Polyurethane Shape Memory Polymers. Effects of Moisture on Electrically Conductive Polyurethane Shape Memory Polymers. Magnetic and Conductive Polyurethane Shape Memory Polymers. Shape Memory Polymer Nanocomposites. Porous Polyurethane Shape Memory Polymers. Shape Memory Effects at Micro and Nanoscales. Wrinkling atop Shape Memory Polymers. Medical Applications of Polyurethane Shape Memory Polymers. Mechanisms of Multi-Shape and Temperature Memory Effects. Future of Polyurethane Shape Memory Polymers.

Chitosan Derivatives. Bioactivities of Chitosan and Its Derivatives. Formation of Chitoan-Based Hydrogels Network. Environment–Stimuli Response of Chitosan-Based Hydrogels. Chitosan-Based Gels for Drug Delivery System. Application of ChitosanBased Gels in Pharmaceuticals. Enzyme Immobilization on Chitosan-Based Supports. Application of Chitosan-Based Biomaterials in Tissue Engineering. Future. Index.

Catalog no. K11120, July 2011, 521 pp. ISBN: 978-1-4398-2114-5, $189.95 / £121.00 Also available as an eBook

Heriot Watt University, Edinburgh, Scotland, UK

“… a comprehensive overview on polyurethane shape memory polymer research. Due to the authors’ long-term research experience, I am optimistic that Polyurethane Shape Memory Polymers will be a success story. Everyone who wants to learn about these fascinating materials or get inspired will find plenty of information and a valuable source of inspiration.” —Thorsten Pretsch, BAM Federal Institute for Materials Research and Testing, Germany

• Covers fabrication and processing as well as thermomechanical and shape memory properties • Provides extensive information on various types of shape memory polymer composites, such as electrically conductive PU SMPs • Addresses the moisture-responsive phenomenon and characterization • Offers broad coverage of recent and developing applications of PU SMPs Selected Contents: Thermomechanical Behavior

Catalog no. K11723, September 2011, 383 pp. ISBN: 978-1-4398-3800-6, $179.95 / £114.00 Also available as an eBook

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Materials Science New!

Multiporphyrin Arrays Fundamentals and Applications

Biomaterials for MEMS Edited by

Mu Chiao

Edited by

University of British Columbia, Vancouver, Canada

Dongho Kim

Jung-Chih Chiao

Institute for NanoBio Molecular Assemblies, Seoul, South Korea

University of Texas at Arlington, USA

This book provides a comprehensive review of the fundamentals and applications of multiporphyrin arrays, ranging from basic spectroscopic features to a wide range of promising applications such as molecular wires, switches, sensors, artificial photosynthetic devices, and dye-sensitized solar cells. It focuses on energy and electron transfer processes occurring in multiporphyrin arrays in various environments, including single-molecule level, composite materials, LB films, and solid surface, to provide a better understanding of photofunctional molecular architectures.

This guide is for practicing engineers, researchers and students interested in MEMS devices and biomaterials and biomedical applications. It is also suitable for engineers and researchers interested in MEMS and its applications but who do not have the necessary background in biomaterials. The book highlights important features and issues of biomaterials that have been used in MEMS and biomedical areas, including the fabrication of devices using biomaterials, biocompatible coatings and issues, thin-film biomaterials and MEMS for tissue engineering, and applications involving MEMS and biomaterials.

Catalog no. N10500, January 2012, 300 pp. ISBN: 978-981-4316-60-6, $249.95 / £159.00

Catalog no. N10421, March 2011, 292 pp. ISBN: 978-981-4241-46-5, $149.95 / £95.00

Also available as an eBook

Also available as an eBook

New!

Handbook of Active Materials for Medical Devices Advances and Applications Edited by

Andres Diaz Lantada

Metals for Biomedical Devices Edited by

M. Niinomi Tohoku University, Japan

This handbook covers biodevices, mainly implantable or quirurgical, for the diagnosis or treatment of different pathologies that benefit from the use of active materials as sensors or actuators. The research presented in this book helps further development of medical devices, based on the additional functionalities of active or “intelligent” materials in sensors and actuators. The main results covered may help with the industrial expansion of this kind of materials as part of more complex systems.

Given their widespread use in medical devices, it is vital that the fundamentals and behavior of metals are understood. In meeting such a need, this volume reviews techniques in metal processing methods and the critical aspects of their behavior that might affect production and application. The text reviews the current status and selection of metals for biomedical devices before moving on to cover mechanical behavior, degradation, and testing. A final section discusses cardiovascular and orthopedic uses and the use of next-generation biomaterials.

Catalog no. N10471, September 2011, 350 pp. ISBN: 978-981-4303-36-1, $249.95 / £159.00

Catalog no. N10188, May 2010, 432 pp. ISBN: 978-1-4398-3107-6, $229.95 / £145.00

Universidad Politecnica de Madrid, Spain

Also available as an eBook

For more information and complete contents, visit www.crcpress.com

21


Materials Science Biobased Surfactants and Detergents

Degradation Rate of Bioresorbable Materials

Synthesis, Properties, and Applications

Prediction and Evaluation

Edited by

Douglas G. Hayes, Dai Kitamoto, Daniel K.Y. Solaiman, and Richard D. Ashby

Edited by

F.J. Buchanan Queen's University Belfast, Northern Ireland, UK

This book provides an overview of biobased surfactants under development, exploring R&D in the industrial sector. Several chapters describe the state of the art in biosurfactants and natural amphiphiles synthesized by microorganisms, including their synthesis and applications. An additional focus area is on the application of biobased surfactants as lung surfactants. Other chapters describe the chemical and enzymatic synthesis and applications consisting of polyols derived from nature.

Bioresorbable materials can be employed to provide significant advances in drug delivery systems and medical implants. The rate of material degradation is critical to performance of implants and the controlled release of drugs. The first section of this volume provides an overview of bioresorbable materials and the biological environment. The book then reviews degradation mechanisms and bioresorption test methods. It also discusses factors influencing bioresorption and explores clinical applications.

Catalog no. N10253, January 2010, 515 pp. ISBN: 978-1-893997-67-7, $225.00 / £146.00

Catalog no. WP7971, October 2008, 320 pp. ISBN: 978-1-4200-7971-5, $269.95 / £142.00

Natural-Based Polymers for Biomedical Applications

Biomedical Composites

Edited by

Edited by

L. Ambrosio University of Naples Federico II, Italy

This book provides a thorough review of the recent progress and future trends in composites for biomedical applications. It concentrates on the research and applications of this increasingly popular family of materials. The book begins with an introduction to the material, focusing on the properties, fabrication and design of composites. It then discusses particular applications and biocompatibility of biocomposites. The final group of chapters analyzes the mechanical behavior and failure of biocomposites and their future potential. Catalog no. N10042, December 2009, 648 pp. ISBN: 978-1-4398-0178-9, $249.95 / £160.00

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Rui L. Reis, Nuno M. Neves, João F. Mano, Manuela E. Gomes, Alexandra P. Marques, and Helena S. Azevedo This work comprehensively reviews the important subject of natural origin biopolymers. The first part discusses the sources, properties, modification, and processing of natural-based polymers. In the second section, surface aspects are reviewed. The next two parts cover natural origin materials for tissue engineering and regenerative medicine, including scaffolds, hydrogels, and injectable systems. The book then reviews the sustained release of molecules. The final section focuses on the biocompatibility of naturalbased polymers. Catalog no. WP7607, September 2008, 760 pp. ISBN: 978-1-4200-7607-3, $334.95 / £184.00

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Biomaterials Education New!

Introduction to Biomedical Engineering Technology Second Edition Laurence Street Rosedale, British Colombia, Canada

Thoroughly revised and updated, this second edition describes current technological devices, the physiological and anatomical basis of their function, their practical applications, and their locations in hospitals. Written by an experienced BMET, this accessible text discusses tools and test equipment, the integration of equipment within the hospital system, and various kinds of hardware related to medical equipment. It also incorporates real-life examples of the work that BMETs do. • Covers a wider range of devices • Includes an expanded section on equipment management • Describes the day-to-day work of BMETs using extensive examples • Offers chapter summaries and questions to aid in reader comprehension • Contains more than 360 illustrations, along with a 16-page insert of photographs of real-life equipment problems • Lists normal medical values, biomedical associations, test equipment manufacturers, helpful Internet resources, and more in the appendices Solutions manual available upon qualifying course adoption

Selected Contents: Introduction. Diagnostic Devices: Part One. Diagnostic Devices: Part Two. Diagnostic Devices: Part Three. Diagnostic Imaging. Treatment Devices: Part One. Treatment Devices: Part Two. Treatment Devices: Part Three. Biomedical Engineering Technologist (BMET) Work. Testers and Tools. Batteries, Radiation, and Computers. Technology Management. Appendices. Index. Catalog no. K12781, October 2011, 391 pp. ISBN: 978-1-4398-6058-8, $89.95 / £56.99 Also available as an eBook

Biomedical Engineering Principles Second Edition Arthur B. Ritter, Vikki Hazelwood, and Antonio Valdevit Stevens Institute of Technology, Hoboken, New Jersey, USA

Alfred N. Ascione Alcatel-Lucent Technologies, New Jersey, USA

Praise for the First Edition: “… an excellent textbook for a class. … For practicing engineers without biomedical engineering background, the book provides an excellent resource to explain the many intricacies of biomedical engineering and provides sufficient background material to make the subject understandable.” —Richard C. Fries, IEEE Engineering in Medicine and Biology Magazine, December 2006

• Includes new chapters on capstone design in biomedical engineering and entrepreneurship • Contains new coverage of systems biology and computational biology • Provides extensively revised and updated chapters on the emerging field of tissue engineering • Offers extensive examples and in-chapter problems Solutions manual available upon qualifying course adoption

Selected Contents: Introduction: Modeling of Physiological Processes. Cell Physiology and Transport. Principles and Biomedical Applications of Hemodynamics. A Systems Approach to Physiology. The Cardiovascular System. Biomedical Signal Processing. Signal Acquisition and Processing. Techniques for Physiological Signal Processing. Examples of Physiological Signal Processing. Principles of Biomechanics. Practical Applications of Biomechanics. Biomaterials. Principles of Biomedical Capstone Design. Unmet Clinical Needs. Entrepreneurship: Reasons why Most Good Designs Never Get to Market. An Engineering Solution in Search of a Biomedical Problem to Solve. Tissue Engineering. Future Trends in BME.

Catalog no. K10621, May 2011, 540 pp. ISBN: 978-1-4398-1232-7, $99.95 / £63.99 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

23


Biomaterials Education For the Lab

New!

For the Classroom

An Introduction to Biomaterials

A Laboratory Course in Biomaterials

Second Edition Edited by

Wujing Xian

Jeffrey O. Hollinger

University of Illinois at UrbanaChampaign, USA

Carnegie Mellon University, Pittsburgh, Pennsylvania, USA

A teaching tool for instructors in biomaterials and bioengineering, this laboratory textbook trains readers in laboratory skills, data analysis, problem solving, and scientific writing. It integrates a variety of principles that include materials science, chemistry, biochemistry, molecular and cell biology, and engineering. Providing detailed descriptions, explanations, and illustrations of experiments, the text also includes a series of questions and answers at the end of each chapter to clarify concepts. Many of the experiments presented are adapted from research papers in biomaterials and bioengineering. • Presents detailed, step-by-step descriptions of lab procedures and explanations for the underlying principles • Contains user-friendly graphic illustrations for the experiments • Provides a series of questions and answers at the end of each chapter to clarify concepts and induce critical thinking • Includes text boxes with in-depth information, case studies, and lab tips • Offers information on equipment, reagents, and supplies for instructors

The second edition of this popular text includes nine new chapters that provide a comprehensive and up-to-date educational framework for biomaterials education. The book explains in vitro and in vivo testing paradigms and provides numerous examples in the chapters on experimental design, laboratory assays, and animal models. Emphasizing the importance of the regulatory process, it describes how innovation in the biomaterials process relates to patentability and inventorship. • Covers wound healing biology and host response to implanted biomaterials • Examines the regulatory process, including standardized product testing • Reviews the innovativeness of biomaterials, with inventions and patents in mind • Considers experimental design, basic scientific methods, and statistics • Includes extensive references for further study • Contains end-of-chapter questions and answers

Selected Contents: Basic Laboratory Skills. Module I. Drug Delivery: Controlled Release of Encapsulated Protein from PLGA Microspheres. Module II. Natural Biomaterials: Collagen and Chitosan. Basic Laboratory Skills II. Cell Culture and Microscopy. Module III. Biocompatibility Testing: Cytotoxicity and Adhesion. Module IV. Tissue Engineering: Organotypic Cultures of Skin Equivalents. Module V. Bioceramics: Porous Hydroxyapatite Composite. Appendix: Answers. Index.

Fundamental Concepts, and a Standardized Approach to Applied Biomaterials Sciences. Biology, Biomechanics, Biomaterial Interactions: Wound Healing Biology. Biology, Biomechanics, Biomaterial Interactions: Cellular Mechanics. Biology, Biomechanics, Biomaterial Interactions: Materials– Host Interactions. Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property: Standardized Materials Testing. Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property: Statistics. Biomaterials Compositions. Biomaterials Applications. Index.

Catalog no. 75829, June 2009, 216 pp. Soft Cover ISBN: 978-1-4200-7582-3, $64.95 / £41.99

Solutions manual available upon qualifying course adoption

Selected Contents: Consensus Definitions,

Catalog no. K10637, November 2011, 644 pp. ISBN: 978-1-4398-1256-3, $119.95 / £48.99 Also available as an eBook

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Biomaterials Education BioMEMS Science and Engineering Perspectives Simona Badilescu and Muthukumaran Packirisamy Concordia University, Montreal, Canada

Covering often overlooked areas in the field of bioMEMS, this volume spans topics associated with biomolecules and complex biological entities as well as subjects directly linked to the design, fabrication, and characterization of devices. Unlike other books, this text aids in the fundamental physiochemical understanding of biological processes relevant to the performance of various biosensing devices. Useful for upperlevel undergraduate and graduate students enrolled in engineering programs, the book includes problems in each chapter and case studies that provide real-life examples. • Provides a concise overview of bioMEMS principles • Incorporates modern applications • Covers fabrication techniques • Includes examples and problems in each chapter • Offers references, review questions, and case studies to aid with reader application Solutions manual available upon qualifying course adoption

Selected Contents: Introduction. Substrate Materials Used in BioMEMS Devices. Biomolecules and Complex Biological Entities: Structure and Properties. Engineering of Bioactive Surfaces. Methods of Study and Characterization of SurfaceModified Substrates. Biosensing Fundamentals. Fabrication of BioMEMS Devices. Introduction to Microfluidics. BioMEMS: Life Science Applications.

Catalog no. K10877, April 2011, 368 pp. ISBN: 978-1-4398-1699-8, $99.95 / £63.99 Also available as an eBook

Biomaterials A Nano Approach Seeram Ramakrishna, Murugan Ramalingam, T.S. Sampath Kumar, and Winston O. Soboyejo From a multidisciplinary point of view, this book examines basic concepts, various processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications. It spans their historical development and reviews recent advances in the field. It describes how basic concepts in nanotechnology are applied to the processing of novel nanobiomaterials, including nanostructured metals and alloys. Presenting illustrative examples and a variety of applications, this text offers a solid framework for understanding present and future trends of biomaterials in human health care systems. • Focuses on the application of nanobiomaterials as a key component in next-generation biomaterials • Covers a range of nanobiomaterials and their potential applications • Discusses materials used for biomedical applications, including tissue engineering and drug delivery • Describes the biological and environmental effects of nanomaterials • Presents case studies that demonstrate the vital role of nanobiomaterials • Includes exercises, illustrative examples, and useful tables Selected Contents: Overview of Biomaterials. Basics of Human Biology. Degradation and Corrosion of Biomaterials. Failure and Tribology of Biomaterials. Nanoscale Phenomena. Metallic Biomaterials. Ceramic Biomaterials. Polymeric Biomaterials. Composite Biomaterials. Nanobiomaterials for Tissue Engineering. Glossary. Exercises. References.

Catalog no. 47817, June 2010, 372 pp. ISBN: 978-1-4200-4781-3, $99.95 / £69.99

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Biomaterials Education / Industry Applications Biomaterials Fabrication and Processing Handbook

Biomedical Microsystems

Edited by

Paul K. Chu

Ellis Meng

City University of Hong Kong, Kowloon

University of Southern California, Los Angeles, USA

Xuanyong Liu

Written by an active researcher named one of Technology Review’s Young Innovators Under 35, this book begins with an introduction to the benefits of miniaturization. It introduces materials, fabrication technology, and the necessary components of all bioMEMS. The author covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering. Detailed examples, exercises, and illustrations help clarify the concepts. • Presents a rigorous, in-depth treatment of bioMEMS materials, methods, processes, and concepts • Emphasizes practical knowledge useful for application to real-world problems • Describes research and commercialized bioMEMS devices as well as emerging applications • Includes detailed examples, laboratory exercises, and a variety of homework problems • Contains numerous illustrations of concepts, processes, and devices Solutions manual available upon qualifying course adoption

Selected Contents: Introduction. BioMEMS Materials. Microfabrication Methods and Processes for BioMEMS. Microfluidics. Lab-on-a-Chip or Micro Total Analysis Systems. Sensing and Detection Methods. Applications to Cells, Nucleic Acids, and Proteins. Clinical Monitoring. MEMS Implants and Bioelectric Interfaces. Index.

Catalog no. 51229, September 2010, 408 pp. ISBN: 978-1-4200-5122-3, $94.95 / £59.99 Also available as an eBook

Shanghai Institute of Ceramics, People’s Republic of China

Comprehensive in scope, this volume focuses on a variety of production and processing aspects of biomaterials. It discusses how scaffolds are used in tissue engineering and describes common implant materials. The book also examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bioMEMS. With contributions from renowned international experts and extensive reference lists in each chapter, this book provides detailed, practical guidance on producing biomaterials and employing them in biomedicine. • Focuses on a variety of fabrication and processing aspects of biomaterials • Discusses how scaffolds are used in tissue engineering • Examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bioMEMS • Describes common implant materials, such as hard tissue, blood contacting, and soft tissue • Explains how to improve the blood compatibility of biomaterials using a novel antithrombin–heparin covalent complex and how to modify the surface of biomaterials using plasma immersion ion implantation and deposition Selected Contents: Tissue Engineering Scaffold Materials. Drug Delivery Systems. Nanobiomaterials and Biosensors. Other Biomaterials. Index.

Catalog no. 7973, March 2008, 720 pp. ISBN: 978-0-8493-7973-4, $169.95 / £108.00 Also available as an eBook

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Industry Applications New!

ISO 13485 A Complete Guide to Quality Management in the Medical Device Industry Itay Abuhav Hinterforst, Switzerland

Written by an experienced industry professional, this practical book provides a complete guide to the ISO 13485 Standard certification for medical device manufacturing in terms of quality control. It covers all the requirements of ISO 13485 and offers a step-by-step comparison between the ISO 13485 and ISO 9001, enabling a sound understanding of these new procedures. • Presents from-the-trenches advice from a quality manager to quality managers and other organizational parties • Interprets the ISO 13485 Standard requirements in detail • Refers to the harmonization of regulatory requirements with the quality management system and the integration of risk management activities throughout the realization processes (with reference to the ISO 14791 standard) • Provides a large number of examples of how to implement the requirements drawn from various sectors • Puts words into actions, translating the requirements and objectives into feasible activities and tasks • Includes a full and comprehensive reference to the interrelations between the different clauses and subclauses of the standard • Compares the ISO 13485 requirements alongside the ISO 9001 requirements using tables that present both of the standards requirements Selected Contents: Scope. Normative References. Terms and Definitions Requirements. Quality Management System. Management Responsibility. Resource Management. Product Realization. Measurement, Analysis, and Improvement. Catalog no. K12946, October 2011, 374 pp. ISBN: 978-1-4398-6611-5, $129.95 / £82.00

Usability Testing of Medical Devices Michael Wiklund, Jonathan Kendler, and Allison Y. Strochlic Wiklund Research & Design, Concord, Massachusetts, USA

This practical guide covers how to conduct usability tests of medical devices. Recognizing that the intended readers are busy and disinclined to read lengthy references, this book has been carefully designed to be concise and visual, allowing readers to jump from one section to another as needed. The book provides a general understanding of usability testing and reviews key concepts. It highlights the challenges of protecting against dangerous errors that could lead to patient injury and death. • Provides a singular source of guidance on conducting a usability test in an industryspecific manner • Presents the information in a highly visual format, making it appealing to marketers, engineers, and regulatory affairs specialists • Draws on the experience of a widely recognized authority in the medical industry on usability testing of medical devices • Includes a CD-ROM that contains videos of mock usability tests, demonstrating the techniques described in the book • Supplies sample test plans for practitioners who would prefer to “plug” content into an authoritative template Selected Contents: Risk Management and Usability Testing. The Commercial Imperative. Testing Costs. Anatomy of a Usability Test. Types of Tests. Writing a Test Plan. Choosing a Participant Sample and Recruiting Participants. Test Environments. Adding Realism. Selecting Tasks. Conducting the Test. Interacting with Test Participants. Documenting the Test. Analyzing Test Data. Reporting Results. Validation Testing. Resources. Index.

Catalog no. K10595, December 2010, 412 pp. ISBN: 978-1-4398-1183-2, $72.95 / £45.99 Also available as an eBook

Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Industry Applications Designing Usability into Medical Products

Handbook of Human Factors in Medical Device Design

Michael E. Wiklund

Edited by

Wiklund Research & Design, Concord, Massachusetts, USA

Matthew B. Weinger

Stephen B. Wilcox

Vanderbilt University, Nashville, Tennessee, USA

Design Science, Philadelphia, Pennsylvania, USA

Michael E. Wiklund

“This book should be on the shelf of anyone involved in the development of medical products. Today, devices are getting more and more complex while caregivers as a whole are much less experienced. User-centered interface design has to make up the difference and this book gives you a plan.”

Daryle J. Gardner-Bonneau

Wiklund Research & Design, Concord, Massachusetts, USA

—Nicholas Barker, Datascope Corp

Advocating a user-centered approach to medical technology design, this book covers the essential processes and specific techniques necessary to produce safe, effective, usable, and appealing medical systems and products. The authors discuss specific design and evaluation methods and tools and present case studies of user-friendly medical technologies and corporate human factors programs. • Presents case-specific guidance on designing user interfaces that will help prevent human error • Provides access to authoritative viewpoints and advice on proven methods for developing user-centered medical products • Includes illustrations that substantiate the design guidance • Contains case studies of human factor programs that illustrate how to approach the task, what the pitfalls are, and how to learn from them • Offers specific design recommendations, such as how to design intuitive control panels • Demonstrates real user-centered design approaches that have led to design excellence and marketplace success Selected Contents: General Principles and Processes. Design Methods and Guidance. Corporate Human Factors Programs. Product Design Case Studies.

Bonneau and Associates, Portage, Michigan, USA

“… interesting, well-written, and achieves the goal of raising the reader’s awareness of important design issues. I loved the book and now that I’ve told my colleagues they want to read it as well … even a reader with experience in equipment design will most definitely gain new insights into the man-machine interface of medical devices.” —Jonathan A. Gaev, Biomedical Engineering Online

Promoting the user-centric design of safe, effective, and usable medical devices, this handbook offers information on general and specific design guidelines. It explores fundamental topics, general human factors principles, the design of specific interface elements, specific types of devices, and devices for particular use environments. It also addresses issues involved in designing medical devices for use outside institutional settings by caregivers, including patients, who may have minimal training and/or health literacy. The book contains product design case studies, examples, tables, illustrations, and cross-references for finding information quick and easy. Selected Contents: General Principles. Basic Human Abilities. Environment of Use. Anthropometry and Biomechanics. Documentation. Testing and Evaluation. Controls. Visual Displays. Connections and Connectors. Alarms. Software User Interface. Workstation. Signs, Symbols, and Markings. Packaging. Device Life Cycle. Hand Tools. Mobile Medical Devices. Home Health Care. Intercultural Design. Catalog no. ER562X, December 2010, 844 pp. ISBN: 978-0-8058-5627-9, $135.95 / £87.00 Also available as an eBook

Catalog no. 2843, February 2005, 376 pp. ISBN: 978-0-8493-2843-5, $139.95 / £89.00 Also available as an eBook

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Forthcoming

The Nanobiotechnology Handbook Edited by

Yubing Xie University at Albany, New York, USA

Offering a uniquely thorough overview of nanobiotechnology and its place in today’s advancements in applied science, this comprehensive survey combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science, bioanalysis, and bioenergy to address the full scope of current and future developments. World-class experts discuss the role of nanobiotechnology in bioanalysis, biomolecular nanotechnology, biosensors, and the use of nanotechnology in biofuels. Extensive references within each chapter facilitate further investigation into the field. Catalog no. K11758, October 2012, c. 1000 pp. ISBN: 978-1-4398-3869-3, $169.95 / £108.00 Also available as an eBook

The Biomedical Engineering Handbook Fourth Edition (Four-Volume Set)

A Laboratory Course in Tissue Engineering Edited by

Melissa Kurtis Micou University of California, San Diego, USA

Dawn Kilkenny University of Toronto, Ontario, Canada

This hands-on lab manual for tissue engineering (TE) instruction contains classic TE experiments as well as modern TE techniques, emphasizing the importance of engineering analysis, mathematical modeling, and statistical design of experiments. It includes over 20 stand-alone experiments that provide more than a semester’s worth of activities, allowing instructors to customize their courses. Along with pre-lab and discussion questions for each experiment, the text presents experiments that use equipment commonly found in labs equipped for tissue culture. Catalog no. K13694, August 2012, c. 256 pp. Soft Cover ISBN: 978-1-4398-7893-4, $59.95 / £38.99 Also available as an eBook

The Medical Device R&D Handbook Second Edition

Joseph D. Bronzino

Edited by

Trinity College, Hartford, Connecticut, USA

Theodore R. Kucklick

Donald R. Peterson University of Connecticut, Farmington, USA

Now in its fourth edition, this handbook presents a substantial revision, with all sections updated to offer the latest research findings. New sections address drugs and devices, personalized medicine, and stem cell engineering. This edition also includes a historical overview and a special section on medical ethics. The set provides complete coverage of biomedical engineering fundamentals, medical devices and systems, computer applications in medicine, and molecular engineering. Catalog no. K11205, October 2012, c. 4500 pp. ISBN: 978-1-4398-2533-4, $279.95 / £178.00 Also available as an eBook

TRKD Medical Devices, Los Gatos, California, USA

Written for medical device designers, biomedical engineering students, physician entrepreneurs, and medical device entrepreneurs, this reference explains the basics on how to prototype and develop a medical device. It discusses the basics of plastics, adhesives, medical needles, and rapid prototyping as well as tips and tools to save time and money. This updated and expanded second edition includes practical advice and interviews from key opinion leaders and pioneers in the field. Extensive references at the end of each chapter enhance additional study. Catalog no. K10598, August 2012, c. 550 pp. ISBN: 978-1-4398-1189-4, $139.95 / £89.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Forthcoming Advances in Therapeutic Engineering

Bacterial Cellulose A Sophisticated Multifunctional Material

Edited by

University of Minho, Braga, Portugal

Wenwei Yue, Subhagata Chattopadhyay, Teik-Cheng Lim, and Rajendra Acharya

Catalog no. K13216, September 2012, c. 250 pp. ISBN: 978-1-4398-6991-8, $99.95 / £63.99

Catalog no. K13287, September 2012, c. 488 pp. ISBN: 978-1-4398-7173-7, $179.95 / £109.00

Also available as an eBook

Also available as an eBook

Miguel Gama

Advances in the Engineering of Polysaccharide Materials

Reliable Design of Medical Devices

by PhosphorylaseCatalyzed Enzymatic Chain-Elongation

Third Edition Richard C. Fries Isorel, Inc., Fitchburg, Wisconsin, USA

Jun-ichi Kadokawa and Yoshiro Kaneko

Catalog no. K14218, September 2012, c. 416 pp. ISBN: 978-1-4398-9491-0, $179.95 / £114.00

Kagoshima University, Japan

Also available as an eBook

Catalog no. N10553, October 2012, c. 200 pp. ISBN: 978-981-4364-45-4, $129.95 / £82.00 Also available as an eBook

Materials and Processes for Medical Devices

Regenerative Engineering Edited by

Cato T. Laurencin and Yusuf Khan

Edited by

University of Connecticut Health Center, Farmington, USA

Consultant, Clearwater, Florida, USA

Catalog no. K10724, September 2012, c. 400 pp. ISBN: 978-1-4398-1412-3, $99.95 / £63.99

Catalog no. K11412, October 2012, c. 472 pp. ISBN: 978-1-4398-2875-5, $149.95 / £95.00

Also available as an eBook

Also available as an eBook

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Contracts for Engineers

Technical Writing

Intellectual Property, Standards, and Ethics

A Practical Guide for Engineers and Scientists

Robert D. Hunter

Phillip A. Laplante

Robert D. Hunter Associates, Austin, Texas, USA

The Pennsylvania State University, Malvern, USA

• Enhance your ability to communicate contractual issues to lawyers and better understand the consequent legal advice • Get background on common law contracts and their relationship to sales contracts in the Uniform Commercial Code • Gain insight into ethics for both individuals and organizations through real-world examples

• Learn how to write, edit, and publish books, articles, reports, and electronic media • Understand the practical considerations in writing technical content. • Look at first-hand examples of writing, editing, and publishing technical materials

Catalog no. K12434, September 2011, 368 pp. ISBN: 978-1-4398-5286-6, $69.95 / £44.99

Catalog no. K11106, July 2011, 250 pp. Soft Cover ISBN: 978-1-4398-2085-8, $39.95 / £25.99 Also available as an eBook

Also available as an eBook

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CRC Press Taylor & Francis Group


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