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Contents
Page 4
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Design and Rehabilitation......................................3 Signals, Sensors, and Instrumentation ..................6 Imaging................................................................12 Biotechnology ......................................................16 Nanotechnology ..................................................22 BioMEMS..............................................................27 Biomaterials and Biological Interfaces ..................28 Cell & Tissue Engineering ....................................36 Biomechanics ......................................................42 Biotransport..........................................................46 General Books in Bioengineering ........................47 Forthcoming ........................................................49
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Design and Rehabilitation From the Rehabilitation Science in Practice Series
Coming Soon!
New!
Ambient Assisted Living
Quality of Life Technology Handbook
Nuno M. Garcia, Joel José P.C. Rodrigues, Dirk Christian Elias, and Miguel Sales Dias Written for students, practitioners and users of Ambient Assisted Living (AAL), this comprehensive reference covers methods, concepts, systems, devices, and services that provide unobtrusive support for the daily needs of an assisted person. It also provides extensive coverage of applications, software, and information management for AAL, as well as coverage of the latest hardware and software for ergonomic design pertaining to AAL. A key concept covered within the reference is ambient intelligence, which refers to electronic environments that are sensitive and responsive to the presence of people. References are provided at the end of each chapter for additional study. • Covers the latest developments in Ambient Assisted Living (AAL) • Provides extensive coverage of applications, software, and information management for AAL • Includes coverage of the latest hardware and software for ergonomic design pertaining to AAL • Offers extensive references at the end of each chapter Selected Contents Enabling and Base Technologies for AAL Applications, Software and Information Management for AAL Designing and Applying AAL Technologies Scenarios and Solutions, Laws and Regulations, Individual and Human Rights
Edited by
Richard Schulz
University of Pittsburgh, Pennsylvania, USA
A collaboration between leading scientists, practitioners, and researchers at Carnegie-Mellon University and the University of Pittsburgh, this book is a comprehensive resource describing Quality of Life (QoL) technologies and their development, evaluation, adoption, and commercialization. It takes an interdisciplinary team approach to the process of technology development for disabled and older persons and discusses the state of the art and future directions of technologies. This work provides direction on how to identify user needs and preferences, engage end-users in the design and development process, and evaluate and commercialize the technologies. • Introduces an innovative model that conceptualizes QoL systems in terms of functional domain, adaptability, user involvement, and systems intelligence • Discusses the current state of the art as well as the future direction of technologies • Provides detailed how-to guidance for each step of the technology developmentcommercialization process in the field • Establishes a framework for a new interdisciplinary science and shows how work requires collaboration among engineers, clinicians, social scientists, and policy experts • Includes illustrations, figures, and tables to clarify concepts Selected Contents Introduction and Conceptual Foundations
Sociological Impacts of AAL
Design, Development, and Evaluation
Catalog no. K13212, January 2013, c. 450 pp. ISBN: 978-1-4398-6984-0, $149.95 / £95.00 Also available as an eBook
Core Technologies and Their Application Transforming Education and the Market Place Catalog no. K14561, October 2012, c. 336 pp. ISBN: 978-1-4665-0534-6, $139.95 / £89.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Design and Rehabilitation From the Rehabilitation Science in Practice Series
New!
New!
Assistive Technology for Blindness and Low Vision
Assistive Technology Assessment Handbook
Edited by
Edited by
Roberto Manduchi and Sri Kurniawan
Stefano Federici
University of Perugia, Italy
University of California, Santa Cruz, USA
Marcia Scherer
This book provides a comprehensive overview of the current state of the art in assistive technology for persons with visual impairment, as well as extensive coverage into promising new research directions. Beginning with a brief overview of the psychopathology of low vision and blindness, the text proceeds with in-depth descriptions of current technology to support independent mobility and orientation, information access (printed information, tactile information, and computers), and life activities (education, work, entertainment), as well as future directions related to the technology for blindness and visual impairment. • Provides a comprehensive overview of the state-of-the art in assistive technology for persons with visual impairment • Details devices such as screen readers, which give a blind person access to the Internet and computer interaction • Covers accessible GPS systems, which provide orientation to an unfamiliar environment • Includes contributions by world-class experts from different countries doing cutting edge research in this field • Contains extensive references at the end of each chapter Selected Contents Introduction. Vision and Vision Rehabilitation. Orientation and Mobility. Low Vision: Types of Vision Loss and Common Effects on Activities of Daily Life. Accessible Global Positioning Systems. Development, Evaluation, and Lessons Learned: A Case Study of Talking Signs® Remote Infrared Audible Signage. Evaluating the Effectiveness of Assistive Travel and Wayfinding Devices for Persons Who Are Blind or Visually Impaired. Sensory Substitution of Vision: Importance of Perceptual and Cognitive Processing. ... Catalog no. K13276, October 2012, c. 433 pp. ISBN: 978-1-4398-7153-9, $119.95 / £76.99 Also available as an eBook
4
Institute for Matching Person & Technology, Webster, New York, USA
"These colleagues are at the forefront of work within the field of assistive technology and have pioneered much of the current thinking resulting in both the delivery of services to individuals and transformational research. ... this book in the way it has brought together such a wide range of committed individuals has as its underpinning philosophy a commitment to listening to and responding positively to the voice of the individual participant." —from the Foreword by Dave J. Muller, Editor-in-Chief, Disability and Rehabilitation
This handbook presents the assessment tools that are essential in a center for technical aid where multidisciplinary teams match the technology to the person who needs it. The book also describes the roles of members of the assessment team—including the profession of psychotechnologist—and reviews cutting-edge technologies for rehabilitation and independent living. Emphasizing the well-being of the person with disabilities, it proposes an ideal model of the assessment process and outlines how the model can be applied in practice internationally. • Brings together in one handbook all the assessment tools needed in a center for technical aid • Describes the professional profiles, skills, and interactions of the multidisciplinary team members • Reviews recent technologies, including brain–computer interfaces and microswitches • Includes numerous black-and-white illustrations and a 16-page color insert • Contains a CD-ROM containing ancillary materials Catalog no. K11756, March 2012, 484 pp. ISBN: 978-1-4398-3865-5, $139.95 / £82.00 Also available as an eBook
Save when you order online at www.crcpress.com
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Design and Rehabilitation From the Rehabilitation Science in Practice Series
Paediatric Rehabilitation Engineering
Usability Testing of Medical Devices
From Disability to Possibility
Michael E. Wiklund, Jonathan Kendler, and Allison Y. Strochlic
Edited by
Wiklund Research & Design, Concord, Massachusetts, USA
Tom Chau
Bloorview Kids Rehab, Toronto, Ontario, Canada
Jillian Fairley
Toronto, Ontario, Canada
Written by international experts, this book provides a synopsis of advances in research in pediatric rehabilitation engineering. Offering a single comprehensive resource, each chapter details a particular area of technology or those developments of particular clinical relevance to pediatric rehabilitation. Each chapter also includes a conceptual description of the technology or underlying scientific principles, followed by a synthesis of relevant literature, recent research advances, selected clinical case studies (where applicable), and perspectives for future directions.
Informative, practical, and engaging, this handbook covers how to conduct usability tests of medical devices. Recognizing that the intended readers are busy and disinclined to read lengthy textbooks, this book has been carefully designed to be concise and visual, allowing readers to jump from one section to another as needed. The book provides a general understanding of usability testing and reviews key concepts. It highlights the challenges of validating that protects against dangerous errors that could lead to patient injury and death. Includes a CD-ROM with videos of mock usability tests
Catalog no. K10595, December 2010, 412 pp. ISBN: 978-1-4398-1183-2, $72.95 / £45.99 Also available as an eBook
• Offers international perspectives • Presents an accessible introduction to pediatric rehabilitation • Provides interdisciplinary resources for up-to-date research findings on physical and cognitive pediatric rehabilitation engineering • Includes extensive references at the end of each chapter
Ergonomics for Rehabilitation Professionals
Selected Contents
Edited by
Introduction to 21st Century Pediatric Rehabilitation Engineering Assistive Technology for Cognitive Rehabilitation in Children Mobile Robotics in the Treatment of Autism Advances in Pediatric Augmentative and Alternative Communication Upper Extremity Prosthetics for Children and Youth Virtual Reality Therapy in Pediatric Rehabilitation Innovations in Switch Access for Children and Youth with Profound Disabilities Physiological Access Modalities: Body Talk for Nonverbal Children Catalog no. K10416, December 2010, 366 pp. ISBN: 978-1-4398-0842-9, $145.95 / £93.00
Shrawan Kumar
University of North Texas, Fort Worth, USA
Designed to meet the diverse needs of therapists, this book presents a new approach to rehabilitation that integrates ergonomics concepts to address the wide range of problems commonly encountered by professionals. It addresses general concepts such as anthropometry and tissue mechanics and examines whole body biomechanics, demonstrating the ergonomic effects of physiological and biomechanical factors. The book also focuses on regional biomechanics, explaining the rationale for ergonomic intervention, and discusses the ergonomic paradigm in rehabilitation, including the use of physical demands analysis. Catalog no. 8146, April 2009, 640 pp. ISBN: 978-0-8493-8146-1, $107.95 / £69.99 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Signals, Sensors, and Instrumentation New Edition of Bestseller!
Also available as an eBook
Biomedical Signal and Image Processing
Heart Rate Variability (HRV) Signal Analysis
New!
Second Edition
Clinical Applications
Kayvan Najarian
Edited by
Virginia Commonwealth University, Richmond, USA
Markad V. Kamath and Adrian Upton
Robert Splinter
University of North Carolina at Charlotte, USA
"This is a great book, ideal for a biomedical signal and image processing course…. a great collection of topics ... highly recommended to any research and educator in this field." —Purang Abolmaesumi, University of British Columbia, Vancouver, Canada
"... balances the coverage of physics of biomedical imaging with biomedical image processing. … I was impressed by how clearly the concepts are explained. ... [includes] programming questions at the end of the chapter that will give the reader the opportunity to try out the signal processing techniques introduced." —Shahram Shirani, McMaster University, Hamilton, Ontario, Canada
"… an excellent bridge between the physiological significance of the methods, and the underlying mathematics. … covers a broad range of biomedical problems. … clear, well written, and easy to follow. … this is an excellent course text book, and also an excellent reference book for professionals." —Dr. Kristian Sandberg, Computational Solutions, Inc., Boulder, Colorado, USA
This book describes fundamental signal and image processing techniques that are used to process biomedical information. It also discusses application of these techniques in the processing of some of the main biomedical signals and images, such as EEG, ECG, MRI, and CT. New features of this edition include the technical updating of each chapter along with the addition of many more examples, the majority of which are MATLAB® based. Solutions manual available with qualifying course adoption
Selected Contents Introduction to Digital Signal and Image Processing Processing of Biomedical Signals Processing of Biomedical Images Catalog no. K13235, May 2012, 411 pp. ISBN: 978-1-4398-7033-4, $99.95 / £63.99
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McMaster University, Hamilton, Ontario, Canada
Mari A. Watanabe
St. Louis University, Missouri, USA
Written for graduate students and professionals dealing with heart rate variability (HRV), this cutting-edge reference reviews how minute variations in the beat-to-beat heart rate are regulated. It explores how these variations can be used as a window to understanding the central and peripheral mechanisms that modulate the autonomic nervous systems. Explaining how HRV is characterized through simple statistics and frequency analysis in healthy human subjects and patients with a variety of diseases, the book provides examples for methods that require mathematical techniques. The authors cite a variety of real-life medical situations and offer extensive end-of-chapter references. • Includes the latest research in HRV • Clarifies the basic physiology of each experimental study and pathology • Illustrates real-life situations in which HRV is applied • Uses examples of HRV to explain all mathematical techniques • Provides extensive references at the end of each chapter Selected Contents Heart Rate Variability: A Historical Perspective Section I Heart Rate Variability Techniques Section II Clinical Applications of Heart Rate Variability—Monitoring Section III Clinical Applications of Heart Rate Variability—Acute Care Section IV Clinical Applications of Heart Rate Variability—Chronic Disorders Catalog no. K12259, October 2012, 532 pp. ISBN: 978-1-4398-4980-4, $149.95 / £95.00
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Signals, Sensors, and Instrumentation New!
Biosignal Processing Principles and Practices Edited by
Hualou Liang
Drexel University, Philadephia, Pennsylvania, USA
Joseph D. Bronzino
Simsbury, Connecticut, USA
Donald R. Peterson
University of Connecticut, Farmington, USA
Providing state-of-the-art coverage of contemporary methods in biosignal processing, this volume emphasizes brain signal analysis. The topics covered reflect an ongoing evolution in biosignal processing. As biomedical data sets grow larger and more complicated, emerging signal processing methods to analyze and interpret these data have gained in importance. The book discusses the process for biosignal analysis and stimulates new ideas and opportunities for developing cutting-edge computational methods for biosignal processing, which will in turn accelerate laboratory discoveries into treatments for patients. • Discusses nonstationary and transient nature of signals by introducing time-frequency analysis and its applications to signal analysis and detection problems in bioengineering • Covers emerging methods for brain signal processing, each focusing on specific non-invasive imaging techniques • Explores a multivariate spectral analysis of EEG data using power, coherence, and second-order blind identification • Introduces a general linear modeling approach for the analysis of induced and evoked response in MEG • Presents the progress in groupwise registration algorithms for effective MRI medical image analysis • Examines the basis of optical imaging, fNIR instrumentation, and signal analysis in various cognitive studies • Reviews recent advances of causal influence measures for analyzing multivariate neural data Catalog no. K13271, October 2012, c. 201 pp. ISBN: 978-1-4398-7143-0, $99.95 / £63.99 Also available as an eBook
New!
Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation Second Edition Robert B. Northrop
University of Connecticut, Storrs, USA
This book helps biomedical engineers understand and design signal conditioning systems using analog integrated circuits. It explains the electronic components and subsystems—the "building blocks"—that are used in ECG, EEG, EMG, ERG, tomographic images, biochemical spectrograms, and other crucial medical applications. This second edition has been substantially updated and revised. It now features a glossary, new end-of-chapter problems, and three new chapters. • Introduces the basic mathematical tools used to describe noise and its propagation through linear systems • Describes, at a basic level, how to improve signal-to-noise ratios with signal averaging and linear filtering • Shows how op amps can be used to build instrumentation amplifiers, isolation amplifiers, active filters, and many other systems and subsystems used in biomedical instrumentation • Features three new chapters addressing power amplifiers; wireless patient monitoring; and RFID, GPS, and ultrasonic tags • Includes an extensive glossary • Provides end-of-chapter problems and examples that emphasize biomedical electronic applications Solutions manual available with qualifying course adoption
Selected Contents Sources and Properties of Biomedical Signals. Properties and Models of Semiconductor Devices Used in Analog Electronic Systems. The Differential Amplifier. General Properties of Electronic, Single-Loop Feedback Systems. ... Catalog no. K12982, March 2012, 578 pp. ISBN: 978-1-4398-6669-6, $119.95 / £76.99 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Signals, Sensors, and Instrumentation Biomedical Sensors and Instruments
Biological and Medical Sensor Technologies
Second Edition Tatsuo Togawa
Waseda University, Tokorozawa, Saitama, Japan
Edited by
Toshiyo Tamura
CMOS Emerging Technologies, Inc., Vancouver, British Columbia, Canada
Chiba University, Chiba, Japan
P. Åke Öberg
Linköping University, Sweden
The living body is a difficult object to measure: accurate measurements of physiological signals require sensors and instruments capable of high specificity and selectivity that do not interfere with the systems under study. As a result, detailed knowledge of sensor and instrument properties is required to be able to select the "best" sensor from one of the many designed to meet these challenges. From the underlying principles to practical applications, this updated edition of Biomedical Sensors and Instruments provides an easy-tounderstand introduction to the various kinds of biomedical sensors. The book presents state-ofthe-art discussions of sensors for the measurements of pressure, flow, motion, temperature, heat flow, evaporation, biopotential, biomagnetism, and chemical quantities.
Krzysztof Iniewski
Edited by a pioneer in the area of advanced semiconductor materials, this book contains contributions from experts who explore the development and use of sensors in biological and medical applications. It covers advanced sensing and communications, modeling of DNA-derivative architecture, and the use of enzyme and quartz crystal microbalance-based biosensors. The book also addresses biosensors in human behavior measurement, sweat rate wearable sensors, and the future of medical imaging, including developments in spatial and spectral resolution of semiconductor detectors. Contributors discuss application of high-resolution CdTe detectors in gamma ray imaging and recent advances in positron emission tomography technology. Selected Contents Part I: Sensors for Biological Applications
Selected Contents
Advanced Sensing and Communication in Biological World. Physics and Modeling of DNA-Derivative Architectures for LongWavelength Bio-Sensing. Label-Free Biosensors for Biomedical Applications: The Potential of Integrated Optical Biosensors and Silicon Photonics. Quartz Crystal Microbalance–Based Biosensors. Toward Printable Lab-on-a-Chip Technologies for Cell Analytics. Construction of Enzyme Biosensors Based on a Commercial Glucose Sensor Platform. Future Directions for Breath Sensors. Solid-State Gas Sensors for Clinical Diagnosis.
Fundamental Concepts
Part II: Sensors for Medical Applications
Pressure Measurements
Biosensors and Human Behavior Measurement: A State-of-the-Art Review. Sweat Rate Wearable Sensors. Future of Medical Imaging. Spatial and Spectral Resolution of Semiconductor Detectors in Medical Imaging. Advances in CMOS SSPM Detectors. High-Resolution CdTe Detectors and Their Application to Gamma-Ray Imaging. Recent Advances in Positron Emission Tomography Technology.
• The organization of topics makes it easy to find the best possible choice of sensors for each measurement situation • More than 300 updated figures and tables facilitate an intuitive understanding • Numerous examples of sensor applications demonstrate practical methods of research • References at the end of each chapter provide convenient sources for further study
Flow Measurement Motion and Force Measurement Temperature, Heat Flow, and Evaporation Measurements Bioelectric and Biomagnetic Measurements Chemical Measurements Catalog no. 9078X, March 2011, 423 pp. ISBN: 978-1-4200-9078-9, $139.95 / £89.00 Also available as an eBook
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Catalog no. K13895, February 2012, 412 pp. ISBN: 978-1-4398-8267-2, $149.95 / £95.00 Also available as an eBook
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Signals, Sensors, and Instrumentation Healthcare Sensor Networks Challenges Toward Practical Implementation
Electromagnetic Fields in Biological Systems
Edited by
Edited by
Daniel Tze Huei Lai and Rezaul Begg
University of Illinois at Chicago, USA
Victoria University, Melbourne, Australia
Marimuthu Palaniswami
University of Melbourne, Parkville, Victoria, Australia
From network deployment to secure monitoring, this book addresses the latest developments in healthcare sensor networks—medical monitoring devices implanted on the body or in the surrounding infrastructure. The text discusses fundamental concepts and provides examples of clinical applications, including sensors to monitor physical activity in children and wearable gait assistants for people with Parkinson’s. Each chapter details a separate challenge in design and implementation. Addressing topics ranging from sensor hardware and the demand for higher data bandwidth to portability and cost, the book highlights the key areas that require further research for HSNs to become a technological and commercially viable reality. • Presents new solutions to human motion monitoring with sensors • Addresses challenges in implementing HSNs, such as user acceptance and expectations • Explores low-power data communications using wireless transmissions through the human body • Highlights novel security measures for protecting confidential patient data • Discusses prospect of continuous sensor network operation based on energy harvesting technology • Offers practical case studies of healthcare sensor networks in use • Includes more than 140 illustrations Selected Contents Sensor Networks in Healthcare: A New Paradigm for Improving Future Global Health. Healthcare and Accelerometry: Applications for Activity Monitoring, Recognition, and Functional Assessment. Intrabody Communication Using Contact Electrodes in Low-Frequency Bands. ... Catalog no. K11159, September 2011, 462 pp. ISBN: 978-1-4398-2181-7, $149.95 / £95.00 Also available as an eBook
James C. Lin
Spanning static fields to terahertz waves, this volume explores the range of consequences electromagnetic fields have on the human body Topics discussed include essential interactions and field coupling phenomena; electric field interactions in cells, focusing on ultrashort, pulsed high-intensity fields; dosimetry or coupling of ELF fields into biological systems; and the historical developments and recent trends in numerical dosimetry. It also discusses mobile communication devices and the dosimetry of RF radiation into the human body, exposure and dosimetry associated with MRI and spectroscopy, and available data on the interaction of terahertz radiation with biological tissues, cells, organelles, and molecules. • Presents the contributions of a panel of international experts • Examines the interaction of electromagnetic fields and waves with biological systems • Spans a variety of topics, from static fields to terahertz waves • Focuses on induced fields and absorbed energy • Spotlights advanced experimental and computational techniques Selected Contents Coupling of Electromagnetic Fields into Biological Systems. Pulsed Electric Fields in Biological Cells and Membranes. Static, Low-Frequency, and Pulsed Magnetic Fields in Biological Systems. Interaction of Extremely Low–Frequency Electromagnetic Fields with Biological Systems. Electromagnetic Field Coupling into Biological Systems. Medical Devices and Systems Exposure and Dosimetry. Terahertz Radiation: Sources, Applications, and Biological Effects at a Tissue, Cellular, and Molecular Level. Index. Catalog no. K12740, October 2011, 458 pp. ISBN: 978-1-4398-5999-5, $149.95 / £95.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Signals, Sensors, and Instrumentation Epileptic Seizures and the EEG Measurement, Models, Detection and Prediction Andrea Varsavsky, Iven Mareels, and Mark Cook
Robert B. Northrop University of Connecticut, Storrs, USA
A study of epilepsy from an engineering perspective, this volume begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis, and modeling of the epileptic brain. It introduces the EEG and provides an explanation of the type of brain activity likely to register in EEG measurements, offering an overview of how these EEG records are and have been analyzed in the past. The book focuses on the problem of seizure detection and surveys the physiologically based dynamic models of brain activity. Finally, it addresses the fundamental question: can seizures be predicted? Catalog no. K10604, December 2010, 370 pp. ISBN: 978-1-4398-1200-6, $145.95 / £93.00 Also available as an eBook
Epilepsy The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics Edited by
Ivan Osorio, Hitten Zaveri, Mark G. Frei, and Susan Arthurs Integrating the studies of epilepsy, neurosciences, computational neurosciences, mathematics, physics, engineering, and medicine, this volume provides the first means to a clear, structured, and enriching multidisciplinary perspective for developing students, researchers, and clinicians in the field of epilepsy. The text gives up to date information on the state of current research, possible future research, and clinical directions in the fields of epilepsy and seizure dynamics. Clear illustrations that illustrate the patterns of brain electrophysiology and behavioral manifestations are provided to aid comprehension. The authors include extensive references in each chapter to enhance further study. Catalog no. K11766, May 2011, 546 pp. ISBN: 978-1-4398-3885-3, $189.95 / £121.00 Also available as an eBook
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Introduction to Complexity and Complex Systems Written for students and professionals in the fields of biomedical engineering, systems biology, biophysics, and physiology, this unique reference covers complexity issues within living systems. Topics include human responses to coping with complex systems, the Law of Unintended Consequences, the relation of complexity to evolution, the complexity inherent in invertebrate immune systems, and the complexity inherent in economic systems. A comprehensive glossary provides acronyms and terms relating to complex, nonlinear biological systems. Dynamic models and homework questions are also included to further aid in understanding. Catalog no. K11775, December 2010, 551 pp. ISBN: 978-1-4398-3901-0, $83.95 / £53.99 Also available as an eBook
Advanced Electroporation Techniques in Biology and Medicine Andrei G. Pakhomov, Damijan Miklavcic, and Marko S. Markov During the last several decades, intense study has taken place on the effects of electromagnetic fields on living tissues. Reflecting this inquiry, this book discusses the theoretical and experimental evidence of these electromagnetic fields and electric pulses and examines their importance in medicine and biology. The authors present the basic techniques applied in electroporation and the advanced methods for creation of nanopores, highlighting their basic science and clinical applications. Topics include nano electroporation, classic electroporaiton, experimental evidence for electroporation of living cells, and electroporation for cancer and wound healing. Catalog no. K11005, June 2010, 528 pp. ISBN: 978-1-4398-1906-7, $145.95 / £93.00 Also available as an eBook
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Signals, Sensors, and Instrumentation Semiconductor Radiation Detection Systems Edited by
Krzysztof Iniewski
CMOS Emerging Technologies, Inc., Vancouver, British Columbia, Canada
Semiconductor Radiation Detection Systems addresses the design of semiconductor detectors and integrated circuits in the context of medical imaging using ionizing radiation. It includes exciting opportunities in X-ray detection, Computer Tomography (CT), bone dosimetry, and nuclear medicine applications such as PET and SPECT. In addition to medical imaging, the book explores other applications of semiconductor radiation detection systems in areas related to security, such as luggage scanning, dirty bomb detection, and border control. Catalog no. K10214, May 2010, 400 pp. ISBN: 978-1-4398-0385-1, $159.95 / £99.00 Also available as an eBook
Basic Introduction to Bioelectromagnetics Second Edition Cynthia Furse, Douglas A. Christensen, and Carl H. Durney University of Utah, Salt Lake City, USA
This revised and updated edition facilitates the process of interdisciplinary research by introducing life scientists to the basic concepts of electromagnetic fields. The book outlines elements of EM that are helpful to life scientists working with physicists and electrical engineers. Each concept is presented with an associated application and discussion. Example applications include MRI, NMR, ultrasound, hyperthermia, neural stimulation, and cardiac pacing/defibrillation. With the liberal use of diagrams and graphs, this text covers the entire frequency spectrum through optical frequencies from a qualitative perspective beneficial to life scientists. Catalog no. 55429, March 2009, 288 pp. ISBN: 978-1-4200-5542-9, $107.95 / £69.99 Also available as an eBook
Signals and Systems Analysis in Biomedical Engineering
New!
Second Edition
Edited by
Robert B. Northrop
Peter Wide
University of Connecticut, Storrs, USA
The interdisciplinary field of biomedical engineering requires its practitioners to know and master not only engineering skills, but also a diversity of material in the biological sciences. This text helps biomedical engineering students and professionals strengthen their skills in the network of applied mathematics that ties together these diverse disciplines. Based on the author's 30 years of experience in teaching as well as his personal research on neurosensory systems, this book, now in its second edition, provides a ready source of information on the specialized mathematical techniques most useful in describing and analyzing biomedical signals. Solutions manual available with qualifying course adoption
Catalog no. K10633, March 2010, 654 pp. ISBN: 978-1-4398-1251-8, $104.95 / £66.99
Artificial Human Sensors Science and Applications
Orebro University, Sweden
"... a thought-provoking overview of the intriguing field of machine sensing and perception based on an ever-evolving human-instrument partnership. It discusses new intelligent technologies that enhance the natural sensing, perception, and mobility abilities of humans, allowing them to have a healthier, more productive, safer and overall better life." — Prof. Emil Petriu, University of Ottawa, Canada
This book discusses human and artificial sensing in conjunction with human perception capabilities. It also discusses the fusion of this sensing information to find answers to questions such as how we can increase our human "fuzzy" decision capability (perception). Catalog no. N10431, March 2012, 220 pp. ISBN: 978-981-4241-58-8, $149.95 / £95.00 Also available as an eBook
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Imaging New!
New!
Image Processing
Human Eye Imaging and Modeling
Tensor Transform and Discrete Tomography with MATLAB®
Edited by
Artyom M. Grigoryan San Antonio, Texas, USA
Merughan M. Grigoryan Yezeman, Armenia
The book is devoted to the problem of image reconstruction from a finite number of projections. It describes in detail 2-D discrete Fourier transform, including properties, fast algorithms, and applications of Fourier transform methods in image processing. It also presents traditional methods of 2D computerized tomography, including Fourier transform-based methods of filtered back projection and algebraic methods. The text shows readers new approaches and new forms of image representation, which can be used effectively in image processing and computerized tomography. All solutions of the image reconstruction problem are accomplished with examples and MATLAB®-based codes. • Presents novel methods in image tomography and new mathematical concepts, including wide-ray direction orthogonal functions • Describes the exact reconstruction of images on 2-D Cartesian grid from their projections • Details programs for image reconstruction • Includes homework problems in each chapter Selected Contents Discrete 2-D Fourier Transform Direction Images Image Sampling Along Directions Main Program of Image Reconstruction Reconstruction for Prime Size Image Method of Particles Methods of Averaging Projections Bibliography Appendices Index Catalog no. K14749, September 2012, c. 456 pp. ISBN: 978-1-4665-0994-8, $149.95 / £95.00 Also available as an eBook
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E.Y.K. Ng, Jen Hong Tan, U. Rajendra Acharya, and Jasjit S. Suri Advanced image processing and mathematical modeling techniques are increasingly being used for the early diagnosis of eye diseases. This comprehensive reference details the latest advances and computer-based techniques in imaging and modeling of the human eye. Featuring contributions by well-known experts in the field, it covers imaging of fundus and infrared images, diagnosis of diabetes retinopathy and glaucoma, estimation of tear evaporation of dry eye, computer simulation of the human eye based on principles of heat transfer, various bioheat equations to predict interior temperatures based on the surface temperatures, and more. • Discusses theory, principles, and the results of human eye imaging • Addresses diabetic eye anomalies and glaucoma imaging • Examines recent developments in ocular thermography • Introduces a novel edge-based smoothed finite element method in the modeling of bioheat transfer for the eye • Presents a non-contact thermal imaging technique as the basis of tear evaporimetry and dry eye diagnosis • Explores state-of-the-art modalities and medical applications • Includes more than 170 black-and-white illustrations and a 32-page color insert Selected Contents Section I: Automated Identification of Diabetes Retinopathy Using Artificial Intelligence Techniques. VAMPIRE: Vessel Assessment and Measurement Platform for Images of the Retina. Formal Design and Development of a Glaucoma Classification System.... Section II: Biomechanical Modeling of the Human Eye with a Focus on the Cornea. Modeling Retinal Laser Surgery in Human Eye. A Geometric Model of the 3D Human Eye and Its Optical Simulation. ... Catalog no. K13217, June 2012, 430 pp. ISBN: 978-1-4398-6993-2, $189.95 / £121.00
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Imaging Lung Imaging and Computer Aided Diagnosis Edited by
Ayman El-Baz
University of Louisville, Kentucky, USA
Jasjit S. Suri
Global Biomedical Technologies, Inc., California, USA
There is an urgent need for new technology to diagnose small, malignant lung nodules early as well as large nodules located away from large diameter airways because current technology— namely, needle biopsy and bronchoscopy—fail to diagnose those cases. This book brings together researchers in pulmonary image analysis to discuss state-of-the-art image processing techniques for detecting and diagnosing lung cancer at an early stage. The book addresses variables and discrepancies in scans and proposes ways of evaluating small lung masses more consistently to allow for more accurate measurement of growth rates and analysis of shape and appearance of the detected lung nodules. • Presents the latest advances in lung imaging • Offers unique chapters dealing with 3D imaging related to pulmonary studies • Discusses the diagnosis of detected lung nodules as well as shape and appearance analysis of lung nodules • Provides extensive references at the end of each chapter for further study • Includes a 16-page color insert and more than 700 black-and-white illustrations Selected Contents A Novel Three-Dimensional Framework for Automatic Lung Segmentation from Low- Dose Computed Tomography Images. Incremental Engineering of Lung Segmentation Systems. 3D MGRF-Based Appearance Modeling for Robust Segmentation of Pulmonary Nodules in 3D LDCT Chest Images. Ground-Glass Nodule Characterization in High-Resolution Computed Tomography Scans. Four-Dimensional Computed Tomography Lung Registration Methods. Pulmonary Kinematics via Registration of Serial Lung Images. Acquisition and Automated Analysis of Normal and Pathological Lungs in Small Animals Using Computed Microtomography. ...
MRI Essentials for Innovative Technologies Giuseppe Placidi
University of L'Aquila, Italy
"The deep physical insight into the relationship between spin dynamics and gradient field modulation expressed in this book paves the way to a completely new family of pulse sequences that may represent a new line of development for MRI. As a whole, this excellent book should be found on the bookshelves of all those specializing in the field of magnetic resonance." —From the Foreword by Antonello Sotgiu, Professor and Chairman, Department of Health Sciences, University of L'Aquila, Italy
"... complete, readable and usable both for research and for specialized learning purposes in areas of advanced MRI imaging techniques. Dr. Placidi indicates a path useful to both physicists and engineers for implementation, and to radiologists and clinicians in thinking of possible new ways to apply the suggested methods." —From the Foreword by Roberto Passariello, M.D., Professor and Chairman, Department of Radiological Sciences, Policlinico Umberto I, Sapienza University of Rome, Italy
This book describes innovative methods to improve magnetic resonance imaging (MRI) beyond its current limitations. The author proposes smart encoding methods and acquisition sequences to deal with frequency displacement due to residual static magnetic field inhomogeneity, motion, and undersampling. After a concise review of basic mathematical tools and the physics of MRI, the book describes each limitation and then proposes solutions for overcoming it. Requiring few or no hardware modifications, these speculative methods represent building blocks for more advanced MRI applications. Includes more than 80 black-and-white illustrations and a six-page color insert
Catalog no. K11872, May 2012, 216 pp. ISBN: 978-1-4398-4040-5, $89.95 / £49.99 Also available as an eBook
Catalog no. K12032, August 2011, 496 pp. ISBN: 978-1-4398-4557-8, $189.95 / £114.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Imaging Coming Soon!
Coherent Raman Scattering Microscopy
New!
Medical Infrared Imaging Principles and Practices
Edited by
Ji-Xin Cheng and Xiaoliang Sunney Xie Covering technical advances and biological applications, this authoritative compendium describes the major developments in platforms and laser sources leading to the routine use of coherent Raman microscopes. It presents the full spectrum of basic and clinical applications of real-time vibrational imaging for in vitro and in vivo systems, showing how these techniques have proven instrumental in disease studies. Edited by one of the pioneers in the field and with contributions from a distinguished team of experts, the book examines existing methods and potential future applications in nanomaterials and live cell imaging. Catalog no. K13060, November 2012, c. 620 pp. ISBN: 978-1-4398-6765-5, $149.95 / £95.00
Mary Diakides, Joseph D. Bronzino, and Donald R. Peterson This book explores new ideas, concepts, and technologies such as dynamic thermal imaging, thermal texture mapping, and thermal multispectral imaging commonly used in the clinical environment. The coverage ranges from historical background, concepts, clinical applications, standards, and infrared technology. Of interest to the medical and biomedical engineering communities, the book can provide many opportunities for developing and conducting multidisciplinary research in many areas of medical infrared imaging. Catalog no. K13338, October 2012, c. 638 pp. ISBN: 978-1-4398-7249-9, $99.95 / £63.99 Also available as an eBook
New!
Medical Imaging
Coming Soon!
Physics of Mammographic Imaging
Principles and Practices Edited by
Mostafa Analoui, Joseph D. Bronzino, and Donald R. Peterson
Edited by
Mia K. Markey
The University of Texas, Austin, USA
Offering a selective review of key imaging modalities, this book focuses on those with established clinical utilization. It provides a detailed overview of x-ray imaging and computed tomography, fundamental concepts in signal acquisition and processes, followed by an overview of functional MRI (fMRI) and chemical shift imaging. It also covers topics in magnetic resonance microcopy, the physics of instrumentation and signal collection, and their application in clinical practice. The selection of topics provides readers with an appreciation of the depth and breadth of the field and the challenges ahead of the technical and clinical community of researchers and practitioners.
A comprehensive treatment of developments in this field, this book covers the fundamentals of image formation, image interpretation, analysis, and modeling. It examines of the use of mammographic imaging in the detection, diagnosis, treatment planning, and monitoring of breast cancer. Expert authors give a balanced summary of core topics such as digital mammography, contrast-enhanced, stereomammography, breast tomosynthesis, and breast CT. The book highlights the use of mammographic imaging with complementary breast imaging modalities such as ultrasound, MRI, and nuclear medicine techniques. It discusses critical issues such as computer-aided diagnosis, informatics, PACS, perception, and quality assurance.
Catalog no. K13254, October 2012, c. 445 pp. ISBN: 978-1-4398-7102-7, $99.95 / £63.99 Also available as an eBook
Catalog no. K13500, November 2012, c. 319 pp. ISBN: 978-1-4398-7544-5, $179.95 / £114.00 Also available as an eBook
University of Connecticut, Farmington, USA
14
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Imaging Coming Soon!
Emerging Imaging Technologies in Medicine
Automated Image Detection of Retinal Pathology
Edited by
Herbert Jelinek
Mark A. Anastasio
Washington University, St. Louis, Missouri, USA
Patrick La Riviere
University of Chicago, Illinois, USA
Catalog no. K13780, December 2012, c. 363 pp. ISBN: 978-1-4398-8041-8, $169.95 / £108.00 Also available as an eBook
New!
Correction Techniques in Emission Tomography
Medical University of Vienna, Austria
Michael J. Cree
University of Waikato, Hamilton, New Zealand
Catalog no. 7556, October 2009, 384 pp. ISBN: 978-0-8493-7556-9, $149.95 / £96.00 Also available as an eBook
New!
Webb's Physics of Medical Imaging Second Edition
Edited by
Edited by
Mohammad Dawood, Xiaoyi Jiang, and Klaus Schäfers
M.A. Flower
European Institute for Molecular Imaging, Münster, Germany
Catalog no. K10659, April 2012, 287 pp. ISBN: 978-1-4398-1298-3, $119.95 / £76.99 Also available as an eBook
Coming Soon!
Monte Carlo Calculations in Nuclear Medicine Second Edition, Applications in Diagnostic Imaging Edited by
Michael Ljungberg and Sven-Erik Strand
Institute of Cancer Research/Royal Marsden NHS Foundation Trust, UK
Catalog no. IP743, June 2012, 864 pp. ISBN: 978-0-7503-0573-0, $89.95 / £49.99 Also available as an eBook
New!
Vibrational Spectroscopy for Tissue Analysis Ihtesham ur Rehman Zanyar Movasaghi
Queen Mary University of London, UK
Shazza Rehman
St. George's Healthcare NHS Trust, West Yorkshire, UK
Michael A. King
Catalog no. K11629, October 2012, c. 336 pp. ISBN: 978-1-4398-3608-8, $159.95 / £99.00 Also available as an eBook
Catalog no. K11910, November 2012, c. 360 pp. ISBN: 978-1-4398-4109-9, $129.95 / £82.00 Also available as an eBook
New!
Lund University Hospital, Sweden
University of Massachusetts Medical Center, Worcester, USA
Coming Soon!
Comprehensive Brachytherapy Physical and Clinical Aspects Edited by
From Bioimaging to Biosensors Noble Metal Nanoparticles in Biodetection Edited by
Chau Lai-Kwan
National Chung Cheng University, Chia-Yi, Taiwan
Jack Venselaar, Dimos Baltas, Ali Soleimani-Meigooni, and Peter J. Hoskin
Huan-Tsung Chang
Catalog no. K11997, November 2012, c. 536 pp. ISBN: 978-1-4398-4498-4, $199.95 / £127.00 Also available as an eBook
Catalog no. N10569, September 2012 ISBN: 978-981-4267-24-3, $149.95 / £95.00 Also available as an eBook
National Taiwan University, Taipei
For more information and complete contents, visit www.crcpress.com
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Biotechnology New!
New!
Introduction to Instrumentation in Life Sciences
Process Validation in Manufacturing of Biopharmaceuticals
Prakash S. Bisen
Defense Research & Development Establishment, Gwalior, India
Anjana Sharma
Edited by
Rani Durgavati University, Jabalpur, India
Anurag S. Rathore
Designed to serve a multitude section of students and researchers diversified in the field of life sciences, pharmacy, biotechnology, microbiology, biochemistry, and environmental sciences, this book addresses the different aspects of instrumentation that hold the key for cuttingedge research and innovative application. The authors emphasize techniques encountered both in the practical classes and also in high through put techniques involved in modern era of commercialization and product inventories. It includes well illustrated diagrams to explain the principles and theories behind these instruments. • Provides a comprehensive overview of techniques and usage of key instrumentation needed in biotechnology and life sciences • Contains unique coverage of chromatography and spectroscopy • Includes a CD-ROM with color illustrations • Supplies exercises at the end of each chapter Selected Contents Microscopy Micrometry Electrochemical Techniques Chromatography Spectroscopy Centrifugation Electrophoresis X-Ray Microanalysis Techniques with Radioisotopes Fermentation Conductivity Meters Glossary Index Catalog no. K14893, September 2012, c. 392 pp. Soft Cover, ISBN: 978-1-4665-1240-5 $79.95 / £49.99 Also available as an eBook
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Third Edition Indian Institute of Technology, New Delhi
Gail Sofer
SofeWare Associates, Austin, Texas, USA
Written by experienced authorities in process validation, this book explores strategies for selecting the most appropriate quality control processes. It offers practical guidelines, recommendations, and an abundance of industrial case studies that demonstrate various techniques and approaches in the validation of biopharmaceutical processes. This third edition of the text addresses the numerous changes made in the pharmaceutical industry as well as the many modifications that have been made to regulations. In addition, the authors also cover advances in biotechnology. • Presents process characterization techniques for scaling down unit operations used in biopharmaceutical manufacturing • Provides practical methods to test raw materials and in-process samples • Overviews the new validation paradigm of process development, process qualification, and continuous monitoring • Discusses background and industry commentary on the final version of the FDA 2011 Guidance for Industry on Process Validation Principles and Practices, issued in final form on January 24, 2011 • Considers potential risks from adventitious agents • Stresses the importance of taking a risk-based approach towards computerized system compliance and how it adds value to the product and process that is commensurate with cost • Presents strategies for a team approach to ensure process validation is carried out according to current expectations Catalog no. K12321, May 2012, 531 pp. ISBN: 978-1-4398-5093-0, $169.95 / £108.00 Also available as an eBook
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Biotechnology
New!
Biotechnology of Plasma Proteins
New!
Microspheres and Microcapsules in Biotechnology
Roger L. Lundblad
Design, Preparation and Applications
Discussing the role of plasma proteins in current biotechnology, this book describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, and mass spectrometry, as well as updates not published since 1975.
Edited by
Lunblad Biotechnology, Chapel Hill, North Carolina, USA
Catalog no. K12286, July 2012, 460 pp. ISBN: 978-1-4398-5026-8, $149.95 / £95.00 Also available as an eBook
Guanghui Ma and Zhi-Guo Su
Chinese Academy of Sciences, Beijing, PR of China
This book focuses on the new microspheres and new microcapsules especially designed and prepared for the applications in biotechnology and biopharmaceuticals, including bio-reaction, bioseparation, bio-formulation, bio-detection, and other new bio-applications. The book provides deep knowledge about the principle of design, preparation methods, and application results of new microsphere and microcapsules for each bioapplication area; identifies problems that need to be studied further; and discusses future prospects. Catalog no. N10573, October 2012, c. 450 pp. ISBN: 978-981-4316-47-7, $149.95 / £95.00 Also available as an eBook
New!
Ocular Drug Delivery Systems Barriers and Application of Nanoparticulate Systems Edited by
Deepak Thassu and Gerald J. Chader Written for academic and industrial researchers in the field of ophthalmology, this book presents research on the development of currently marketed devices and recent trends for the future delivery of drugs topically to the posterior eye. As the only book to cover drug delivery barriers and the application of nano-medicines to the eye, it includes chapters on ocular physiology and the application of nanoparticles-based delivery systems to enhance drug efficacy. Contributors include leading eye researchers, surgeons, and pharmacologists from academia, the National Eye Institute, and leading ophthalmic companies such as Pfizer, Allergan, and Novartis. Catalog no. K12138, October 2012, c. 464 pp. ISBN: 978-1-4398-4800-5, $169.95 / £108.00 Also available as an eBook
Micro and Nano Techniques for the Handling of Biological Samples Jaime Castillo-León, Winnie Edith Svendsen, and Maria Dimaki
Technical University of Denmark, Lyngby
The techniques and tools used to understand many biological problems must be able to handle biological material without damaging or altering its natural state. This book assesses various micro and nano techniques currently available to handle these materials. It shows how the techniques can effectively manipulate biological samples, and highlights the advantages and shortcomings of each. The authors also help readers understand how the manipulation tools work and how to determine the appropriate tool for their needs. Catalog no. K11354, August 2011, 255 pp. ISBN: 978-1-4398-2743-7, $129.95 / £82.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Biotechnology From Esteemed Author Syed Imtiaz Haider
New!
Quality Operations Procedures for Pharmaceutical, API, and Biotechnology Syed Imtiaz Haider and Erfan Syed Asif This book classifies the various aspects of quality operations as separately designed operating procedures and provides a systematic description for each element. Addressing local and international compliance, the authors present technical solutions to fulfill the needs of quality assurance and quality control systems of all grades. The text presents standard operating procedures for documentation guidelines, validation guidelines, handling of materials in microbiological labs, process simulation testing, conducting internal audits, and chemical and biological testing. • Provides a valuable tool for quality control and quality assurance personnel • Presents standard operation procedures for the most common systems in quality assurance and quality control • Addresses local and international regulatory compliance issues • Contains ready-to-use key performance indicator templates on a CD-ROM Selected Contents Handling of Sampled Material. Control of Incoming Materials used in Production. Control of Bulk and Intermediate Products. Checking of Finished Products. Destruction of Disposal Samples after Complete Testing and Reference Samples after Expiry. Recording the Analysis and Controlling the Analytical Registers and Records. Testing of Finished Products. Microbiological Monitoring Program. Clothing in Microbiology Laboratory. Microbiological Media Handling. General Cleaning and Sanitation of Microbiological Laboratory. Managing Primary and Secondary Reference Standards in the Quality Control Laboratory. Handling of Raw/Packaging Materials and Finished Samples in Reference Room. Catalog no. K14029, June 2012, 584 pp. ISBN: 978-1-4398-8690-8, $129.95 / £82.00 Also available as an eBook
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Biotechnology A Comprehensive Training Guide for the Biotechnology Industry Syed Imtiaz Haider and Anika Ashtok
Julphar Gulf Pharmaceutical Industries, United Arab Emirates
Filled with expert advice, this guide provides concise information covering the concepts and techniques needed to ensure product consistency, potency, efficacy, and safety in the biotechnology and biopharmaceutical industries. A valuable quality tool for both new and existing manufacturers, this text presents step-by-step guidance for optimizing research and maximizing expenditures so as to gain a competitive advantage. It discusses ways to avoid delays to market, reduce product and process failures, develop skilled employees, and maintain both local and international regulatory compliance. • Provides a training manual for the development, manufacturing, auditing, and validation of biopharmaceuticals • Includes a CD-ROM that can be tailored to add changes and in-house training requirements • Incorporates both local and international regulatory compliance • Offers step-by-step guidance on training new and existing staff on biotechnology concepts Selected Contents Microbial Growth Text. Culturing Microorganisms. Bioreactor Configurations Text. Bioreactor Design Features Text. Lyophilization: Growing with Biotechnology Text. Shear Effects in Culture Text. Energy Input in Bioreactors Text. Downstream Processing Text. Mammalian Cell Cultures Text. Plant Cell Cultures Text. Fermentation Text. Characteristics of Cells in Culture Text. Cell Lysis Text. Cells Fractionation Text. Centrifugation Text. Homogenization Text. Refolding of Inclusion Bodies Text. Solubilization and Refolding of Proteins Text. Inclusion Bodies Solubilization Text. Sludge Treatment Text. Freeze Drying Text. Vacuum Drying Text. Diafilteration Text. ... Catalog no. 84488, April 2009, 868 pp. Soft Cover, ISBN: 978-1-4200-8448-1 $107.95 / £69.99 Also available as an eBook
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Biotechnology From Esteemed Author Syed Imtiaz Haider
Quality Control Training Manual Comprehensive Training Guide for API, Finished Pharmaceutical and Biotechnologies Laboratories Syed Imtiaz Haider Syed Erfan Asif Written to help companies comply with GMP, GLP, and validation requirements imposed by the FDA and regulatory bodies worldwide, this book presents cost-effective training courses that cover how to apply advances in the life sciences to produce commercially viable biotech products and services in terms of quality, safety, and efficacy. This book and its accompanying CD-ROM comprise detailed text, summaries, test papers, and answers to test papers, providing an administrative solution for management. • Provides the FDA, Health Canada, WHO, and EMEA guidelines directly applicable to pharmaceutical laboratory-related issues • Offers generic formats and styles that can be customized to any organization and help management build quality into routine operations to comply with regulatory requirements • Contains ready-to-use training courses that supply a good source of training material for experienced and inexperienced practitioners in the biotechnology/biopharmaceutical industries • Includes a CD-ROM with downloadable training courses that can be adopted and directly customized to a particular organization • Supplies ready-to-use test papers that allow end users to record all raw data up to the issuance of the attached certificate Selected Contents Preface. Analytical Methods, Techniques and Quality Measures for General. Pharmaceutical Products. Analytical Methods and Techniques for Biological Products. Laboratory Training Manual. Assessment of Training Procedures. ... Catalog no. K12268, February 2011, 484 pp. ISBN: 978-1-4398-4994-1, $139.95 / £89.00 Also available as an eBook
Cleaning Validation Manual A Comprehensive Guide for the Pharmaceutical and Biotechnology Industries Syed Imtiaz Haider Syed Erfan Asif With over 20 easy-to-use template protocols for cleaning validation of extensively used equipments, this book provides technical solutions to assist in fulfilling the training needs of finished pharmaceutical manufacturers. Drawing on the authors’ more than two decades of experience, the text offers hands-on training based on current approaches and techniques. The manual is organized as a database to support those involved in the development, manufacturing, auditing, and validation of bio-pharmaceuticals on a pilot scale, that can lead to scaled-up production. It also provides exclusive training guidelines in a CD-ROM to enable the users to amend or adapt processes as necessary. • Supplies a basic education of cleaning validation • Offers an advanced approach to validation professionals who are already in the field to implement and execute a thorough cleaning validation program • Includes 23 easy-to-use template protocols for cleaning validation of extensively and most commonly used equipments, with sampling points identified through pictures • Covers a wide range of active ingredients, including their level of solubility in water and potency/toxicity so as to provide an easy way for validation professionals to create a worst-case matrix for different equipment • Provides a complete tool to understand, learn, think, and implement a validation program Catalog no. K11299, May 2010, 608 pp. ISBN: 978-1-4398-2660-7, $145.95 / £93.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Biotechnology OMICS
Healthcare Biotechnology
Biomedical Perspectives and Applications
A Practical Guide Dimitris Dogramatzis Dogramatzis Pharmacy, Athens, Greece
Edited by
Debmalya Barh
Institute of Integrative Omics and Applied Biotechnology, West Bengal, India
Kenneth Blum and Margaret A. Madigan
"The section on marketing is also particularly strong and well thought through. ... provides insight into the biotechnology business sector." —British Journal of Biomedical Science
LifeGen, Inc., San Diego, California, USA
“… this book will be intensively useful to scientists from both academia and industry, teachers and professors, health professionals, and mostly students, who should be encouraged to study and learn from its wisdom.” —From the Foreword by Debasis Bagchi, Department of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy
A reflection of the explosion of research and development in this field, this book explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. Catalog no. K12277, November 2011, 613 pp. ISBN: 978-1-4398-5008-4, $139.95 / £89.00 Also available as an eBook
Biotechnology Operations
Focusing on the management of health-care related biotechnology, this text is a practical guide assisting all healthcare related biotech professionals in their day-to-day activities. It contains chapters on bioeconomy, biolicensing, biofinance, biopartnering, biodrug research, biomarket planning, biopromotion, product life cycle management, and biobusiness models. Written by a well-established registered pharmacist, this reference is appropriate for graduate students and industry professionals. Catalog no. K12108, December 2010, 689 pp. ISBN: 978-1-4398-4746-6, $104.95 / £66.99 Also available as an eBook
Porous Media
Principles and Practices
Applications in Biological Systems and Biotechnology
Michael J. Roy
Edited by
University of Wisconsin-Madison, USA
Applying the author's experience teaching the subject and working in both industry and government, this book introduces key biotechnology developments and covers critical elements, such as project management, regulatory affairs, quality assurance, biomanufacturing, quality control, nonclinical safety testing, and clinical evaluation. The author discusses these subjects in relation to development planning, process and pathways, management of integrated projects, and the business and economic aspects of development. Using simple language and explanatory figures, it describes the functional areas that must be successfully integrated to safely and efficiently bring a biotechnology product to market. Catalog no. K11486, March 2011, 416 pp. ISBN: 978-1-4398-3027-7, $99.95 / £63.99 Also available as an eBook
20
Kambiz Vafai
University of California, Riverside, USA
Presenting recent research advancements, this volume explores innovative approaches to effectively apply existing porous media technologies to biomedical applications. In each peerreviewed chapter, world-class scientists and engineers address significant problems and discuss exciting research in biological systems. They cover various transport processes, mechanical behavior, and material properties of biological tissues from a porous media point of view. The book also presents pertinent aspects of experimental work and numerical techniques and discusses the modeling of several phenomena, including flow changes in cerebral aneurysms, biomass growth, marine systems, and tissue homeostasis and repair. Catalog no. 65416, August 2010, 632 pp. ISBN: 978-1-4200-6541-1, $149.95 / £95.00 Also available as an eBook
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Biotechnology Coming Soon! New!
Biotechnology of Fungal Genes Edited by
V. K. Gupta and M. Ayyachamy
National University of Ireland, Galway, Ireland
Focusing on filamentous fungi, this book highlights the advances of the past decade, both in methodology and in the understanding of genomic organization and regulation of gene and pathway expression. Catalog no. N10536, March 2012, 400 pp. ISBN: 978-1-57808-787-7, $139.95 / £89.00 Also available as an eBook
CMOS Nanoelectronics Innovative Devices, Architectures, and Applications Edited by
Viral Diagnostics Advances and Applications Edited by
Robert S. Marks, Leslie Lobel, and Amadou Sall Covering a spectrm of topics, this book examines the diagnostics and monitoring of viral ailments with an emphasis on the newer technologies in development, such as optical fiber and electrochemical immunosensors, reverse genetics, luminescent molecular imprints of neutrophil biomarkers and many others. Catalog no. N10588, November 2012, c. 400 pp. ISBN: 978-981-4364-43-0, $149.95 / £95.00 Also available as an eBook
Coming Soon!
Bioseparation Technology Neeraj Mishra and Akhilesh Dubey
This book covers one of the most important device architectures that have been widely researched to extend the transistor scaling: FinFET.
Designed for those with a background in engineering or biology, this text explores the fundamentals of the emerging field of bioseparation technology.
Catalog no. N10509, August 2012, 300 pp., ISBN: 978-981-4364-02-7, $149.95 / £95.00 Also available as an eBook
Catalog no. N10039, December 2012, c. 300 pp. Soft Cover, ISBN: 978-1-4398-0172-7 $49.95 / £31.99
Nadine Collaert
IMEC, Leuven, Belgium
Coming Soon! New!
Handbook of Biofunctional Surfaces
Handbook of Multifunctional Molecular Materials
Edited by
Edited by
Wolfgang Knoll
Lahcene Ouahab
This book describes the design, synthesis, assembly and characterization, and the bio(medical) application of interfacial layers on solid substrates with molecularly or supra-molecularly controlled architectures.
This book provides a comprehensive overview of multifunctional molecular materials that involve coexistence or interplay or synergy between multiple physical properties. It focuses on electrical conductivity, magnetism, single-molecule magnets behavior, chirality, spin crossover, and luminescence.
Catalog no. N10502, September 2012, c. 800 pp. ISBN: 978-981-4316-63-7, $425.00 / £270.00 Also available as an eBook
Catalog no. N10510, December 2012, c. 400 pp. ISBN: 978-981-4364-29-4, $249.95 / £159.00 Also available as an eBook
Austrian Institute of Technology, Vienna
For more information and complete contents, visit www.crcpress.com
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Nanotechnology
Coming Soon!
Learning Bio-MicroNanotechnology Mel I. Mendelson
Coming Soon!
The Nanobiotechnology Handbook
Loyola Marymount University, Los Angeles, California, USA
Edited by
A primary text for undergraduate nanotechnology courses, this book is designed for students who lack a cross-disciplinary background and knowledge of micro- and nanotechnology. Clearly and concisely written, it contains many examples, questions, and problems divided into three hierarchical learning skills: understanding, analyzing, and evaluating the concepts. The author attempts to break down the boundaries between biology, chemistry, physics, engineering and ethics. He accomplishes this by co-mingling the vocabulary and concepts of these disciplines around bio-applications. Copiously illustrated, this new text leans heavily towards biological and biomedical applications and includes a comprehensive chapter on ethics.
University at Albany, State University of New York, USA
• Breaks down the barriers between biology, chemistry, physics, engineering, and ethics with cross-disciplinary coverage
Yubing Xie
Offering a uniquely thorough overview of nanobiotechnology and its place in today’s advancements in applied science, this comprehensive survey combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science, bioanalysis, and bioenergy to address the full scope of current and future developments. World-class experts discuss the role of nanobiotechnology in bioanalysis, biomolecular nanotechnology, biosensors, and biofuels. Extensive references within each chapter facilitate further investigation into the field. • Draws on the expertise of world-class contributors from a number of different countries
• Emphasizes ethics throughout the text
• Provides a thoroughly comprehensive overview of all major aspects of nanobiotechnology
• Includes extensive references at the end of each chapter
• Details the role of nanobiotechnology in bioanalysis
Solutions manual available with qualifying course adoption
• Covers the use of nanotechnology in bioenergy and biofuels
Selected Contents Thinking Small and Big Biomolecules and Cells Molecular Chemistry Bit of Physics Engineering Bits and Bytes Seeing Small Things Nanoelectronics Microelectromechanical Systems Nanotechnology and Cancer Risks: Nano or Mega? Ethics and Social Relevance Self-Assembled Future Appendices Catalog no. 82035, October 2012, c. 614 pp. ISBN: 978-1-4200-8203-6, $89.95 / £57.99 Also available as an eBook
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• Offers extensive references within each chapter to facilitate further study Selected Contents Biomimetic Nanotechnology Nanobiofabrication Nanobioprocessing Biomolecular and Cellular Manipulation and Detection Biomedical Nanotechnology Nanobiotechnology Impacts Catalog no. K11758, November 2012, c. 664 pp. ISBN: 978-1-4398-3869-3, $169.95 / £108.00 Also available as an eBook
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Nanotechnology New!
Handbook of Nanoscience, Engineering, and Technology
Nanofabrication Handbook
Third Edition Edited by
Lawrence Berkeley National Laboratory, Berkeley, California, USA
William A. Goddard III
Satoshi Kawata
California Institute of Technology, Pasadena, USA
Donald W. Brenner and Gerald J. Iafrate North Carolina State University, Raleigh, USA
Sergey Edward Lyshevski
Rochester Institute of Technology, New York, USA
Praise for Previous Editions “This book gives the reader access to a huge wealth of ideas that may spur new ideas in the area of nanotechnology they are working in.” —IEEE Electrical Insulation Magazine
In his 1959 address, "There is Plenty of Room at the Bottom," Richard P. Feynman speculated about manipulating materials atom by atom and challenged the technical community "to find ways of manipulating and controlling things on a small scale." This visionary challenge has now become a reality, with recent advances enabling atomistic-level tailoring and control of materials. Exemplifying Feynman’s vision, Handbook of Nanoscience, Engineering, and Technology, Third Edition continues to explore innovative nanoscience, engineering, and technology areas. Along with updating all chapters, this third edition extends the coverage of emerging nano areas even further. Two entirely new sections on energy and biology cover nanomaterials for energy storage devices, photovoltaics, DNA devices and assembly, digital microfluidic lab-on-a-chip, and much more. This edition also includes new chapters on nanomagnet logic, quantum transport at the nanoscale, terahertz emission from Bloch oscillator systems, molecular logic, electronic optics in graphene, and electromagnetic metamaterials. With contributions from top scientists and researchers around the globe, this color handbook presents a unified, up-to-date account of the most promising technologies and developments in the nano field. It sets the stage for the next revolution of nanoscale manufacturing— where scalable technologies are used to manufacture large numbers of devices with complex functionalities.
Edited by
Stefano Cabrini
Osaka University, Japan
“... a broad topical introduction to nanofabrication methods and applications. It is rich with illustrations and the authors of the individual chapters have made a real effort to introduce readers to the basic concepts in understandable terms while also capturing the current leading edge in their field. The amazing micrographs of prototype structures that are documented throughout the pages offer an inspiring snapshot of the many and varied accomplishments of the researchers working in these technology development and application fields … a solid introduction to methods in current use in nanoscale research ... the breadth of topics will also permit experienced practitioners to learn about methods and applications outside their own areas of experience.” —Donald Tennant, Director of Operations, Cornell NanoScale Science and Technology Facility
“An impressive work covering all the important nanofabrication topics and contents … Highly recommended.” —Professor Din Ping Tsai, National Taiwan University
This comprehensive handbook presents a unique collection of new and important approaches to nanofabrication, from electron beam lithography, focused ion beam, and optical lithography to two-photon lithography, self assembly, and plasmonic nanolithography. Contributors from leading research facilities and academic institutions offer hands-on instructions and examples and pave the way for future research. The practical information provided in the book gives readers a foundation to enter the complex world of nanofabrication and helps them select the proper fabricating technique for their experiments. Catalog no. 90526, February 2012, 546 pp. ISBN: 978-1-4200-9052-9, $129.95 / £82.00 Also available as an eBook
Catalog no. K12751, June 2012, 1093 pp. ISBN: 978-1-4398-6015-1, $149.95 / £95.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Nanotechnology Nanotechnology Understanding Small Systems, Second Edition
Simulations in Nanobiotechnology
Ben Rogers
Reno, Nevada, USA
Edited by
Sumita Pennathur
Kilho Eom
University of California, Santa Barbara, USA
Korea University, Seoul, South Korea
Jesse Adams
Nevada Nano, Inc., Reno, USA
"... takes the revolutionary concepts and techniques that have traditionally been fodder for graduate study and makes them accessible for all. Covering subjects ranging from materials science to mechanics and biotechnology to photonics, [the authors] deftly introduce the reader to each topic and quickly explain why it is important on the nanoscale. An exciting feature is the ‘back of the envelope’ examples, where the reader is walked through ‘quick and dirty’ calculations to illustrate and understand (mathematically) the complex concepts discussed. ... this outstanding introduction to the broad field of nanotechnology provides a solid foundation for further study. Summing Up: Highly recommended.” —N.M. Fahrenkopf, University at Albany, in CHOICE
Working from the ground up, this unique work provides a detailed yet accessible introduction to the world’s fastest growing field. Through realworld examples, problems, illustrations, and applications, the authors accomplish the delicate task of keeping the book engaging while not glossing over real explanations of complex concepts. They take a systems approach, demonstrating how an understanding of the various areas underlying nanotechnology come together to create systems with unique functions and characteristics. Solutions manual available with qualifying course adoption
Selected Contents Big Picture and Principles of the Small World. Introduction to Miniaturization. Introduction to Nanoscale Physics. Nanomaterials. Nanomechanics. Nanoelectronics. Nanoscale Heat Transfer. Nanophotonics. Nanoscale Fluid Mechanics. Nanobiotechnology. Index. Catalog no. K12225, July 2011, 421 pp. ISBN: 978-1-4398-4920-0, $99.95 / £63.99 Also available as an eBook
Until recently, computational studies of biomolecules and nanomaterials have considered the two subjects separately. This book provides insights into computational simulations of biomolecules and nanomaterials collectively. It also examines novel modeling concepts at the nanobio-interface: interactions between biomolecules and nanomaterials, such as DNA-wrapped nanotubes, nanobiosensors, and biomimetic materials. Expert contributors from around the world address such important topics as the molecular dynamics of protein translocation, coarse-grained modeling of CNT-DNA interaction, multi-scale modeling of nanowire resonator sensors, and the molecular dynamics simulation of protein mechanics. • Provides a quantitative understanding of the mechanical function of biological molecules and nanomaterials • Includes general computational schemes with various approaches from atomic simulations to continuum simulations • Addresses the theoretical/simulation side of nanobiotechnology • Presents case studies to clarify material Selected Contents Introduction. Molecular Dynamics of Protein Translocation. Coarse-Grained Modeling of DNA Translocation through Nanopore. Atomistic Simulation of Auger Process in Nanoparticle-Based Theragnostics. CoarseGrained Modeling of CNT-DNA Interaction. Molecular Dynamics of CNT-DNA Interaction. Modeling of CNT-DNA Hybrid Complex. Coarse-Grained Modeling of Nano-CantileverBased DNA Detection. Coarse-Grained Modeling of Micro- or Nano-Cantilever Sensors for Atomistic Detection. Continuum Modeling of CNT -Based Molecular Recognitions. MultiScale Modeling of Nanowire Resonator Sensors. Cauchy-Born Rule for Modeling Graphene Sheet. Coarse-Grained Modeling of SingleMolecule Experiments. ... Catalog no. K11581, October 2011, 562 pp. ISBN: 978-1-4398-3504-3, $139.95 / £89.00 Also available as an eBook
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Nanotechnology Bionanotechnology
From David E. Reisner
Maheshwar Sharon
IIT Bombay (retired), Birla College, Nanotechnology Research Center, India
Madhuri Sharon
Monad Nanotech Pvt. Limited, Mumbai, India
Highlighting the human applications of the science, this volume discusses the fundamental concepts and underlying science of bionanotechnology, and the bionanomachines that result from research into this exciting new field. Distilling the author’s research and groundbreaking original experimentation, chapters cover bionanomachines and their use with and manipulation of DNA, RNA, proteins, carbohydrates and lipids. Well-documented and authoritative, this book offers students and scientists alike the foundational information required to advance this powerful and potentially life-altering field. Catalog no. K12393, May 2012, 300 pp. ISBN: 978-1-4398-5214-9, $79.95 / £49.99
New!
Nanostructures and Nanoconstructions based on DNA Yuri M. Yevdokimov, V.I. Salyanov, and S.G. Skuridin
Engelhardt Institute of Molecular Biology, Moscow, Russian Federation
Written for chemists, physicists, molecular biologists, and students in related fields, this reference focuses on information presently available on the specific properties of metallic nanoparticles. It compares their properties with those related to nanoobjects formed by biological molecules. It also discloses details of formation and physicochemical peculiarities of the DNA nanostructures and DNA-based nanoconstructions. Timely in publication, the reference contains more DNA physics and molecular biology than other published titles. Catalog no. K14579, June 2012, 250 pp. ISBN: 978-1-4665-0569-8, $139.95 / £89.00 Also available as an eBook
Bionanotechnology II Global Prospects Edited by
David E. Reisner
The Nano Group, Inc., Farmington, Connecticut, USA
A blend of information from the Biomedical Engineering Handbook and new material, this volume draws on the experience of experts from countries around the world. Reflecting the increasing importance of nanomedicine and biotechnology, this book covers topics such as biomimicry, stem cells, optical togs, and nanocoatings for medical implantable devices. It provides insights into the food and cosmetics industries, as well as cardiac diagnosis, batteries, drug delivery, photonics, and DNA building blocks. It also discusses protein devices, quantum dots, bioanalysis, optics, nanomedicine, personalized medicine, and the business of emerging bionanotech companies. Catalog no. K10254, August 2011, 583 pp. ISBN: 978-1-4398-0463-6, $99.95 / £63.99 Also available as an eBook
Bionanotechnology Global Prospects Edited by
David E. Reisner
The Nano Group, Inc., Farmington, Connecticut, USA
As the impact of nanotechnology continues to grow, it is important for the modern biomedical engineer to have a deeply rooted understanding of bionanotechnologies. Featuring chapters drawn from the third edition of the bestselling Handbook of Biomedical Engineering as well as new contributions, this book takes a broad survey of the current research and activities that are shaping this burgeoning field. Covering both technical and non-technical areas, the book discusses the role of nanotechnology in novel medical devices, bioanalytical technologies, and nano-biomaterials as well as intellectual property issues unique to nanotechnologies. Catalog no. 7528, July 2008, 368 pp. ISBN: 978-0-8493-7528-6, $104.95 / £66.99 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Nanotechnology Nano- and Biocomposites Edited by
Alan Kin-tak Lau
University of Southern Queensland, Australia and The Hong Kong Polytechnic University, Kowloon
Coming Soon!
Consumers and Nanotechnology
Farzana Hussain
Deliberative Processes, Social Barriers and Methodologies
Khalid Lafdi
Harald Throne-Holst, Eivind Soto, Pal Strandbakken, and Gerd Scholl
Oregon State University, Corvallis, USA University of Dayton, Ohio, USA
Catalog no. 8027X, August 2009, 408 pp. ISBN: 978-1-4200-8027-8, $174.95 / £112.00 Also available as an eBook
Catalog no. N10492, November 2012, c. 300 pp. ISBN: 978-981-4316-16-3, $149.95 / £95.00 Also available as an eBook
Coming Soon!
New!
Nanomedicine and Drug Delivery
Self-Assembled Peptide Nanostructures
Edited by
Advances and Applications in Nanobiotechnology
Mathew Sebastian
Edited by
Neethu Ninan
Winnie Edith Svendsen, Jaime Castillo-León, and Luigi Sasso
Point Pleasant, New Jersey, USA Mahatma Gandhi University, Kerala, India
A. K. Haghi
University of Guilan, Iran
Catalog no. N10640, July 2012, 270 pp. ISBN: 978-1-926895-17-8, $149.95 / £95.00 Also available as an eBook
Technical University of Denmark, Lyngby
Catalog no. N10551, November 2012, c. 250 pp. ISBN: 978-981-4316-94-1, $149.95 / £95.00 Also available as an eBook
New! New!
Responsible Nanobiotechnology Philosophy and Ethics Armin Grunwald
Karlsruhe Institute of Technology, Germany
Catalog no. N10506, July 2012, 300 pp. ISBN: 978-981-4316-80-4, $149.95 / £95.00 Also available as an eBook
Understanding Nanomedicine An Introductory Textbook Rob Burgess
Medical Nanotechnologies Incorporated, Richardson, Texas, USA
Catalog no. N10477, June 2012, 524 pp. ISBN: 978-981-4316-38-5, $149.95 / £95.00 Also available as an eBook
New! New!
Molecular Motors in Bionanotechnology
Nanomedicine and Cancer Therapies Edited by
Keith Firman and James Youell University of Portsmouth, UK
Mathew Sebastian, Neethu Ninan, and Eldho Elias
Catalog no. N10568, August 2012, 300 pp. ISBN: 978-981-4267-02-1, $149.95 / £95.00 Also available as an eBook
Catalog no. N10641, July 2012, 250 pp. ISBN: 978-1-926895-18-5, $149.95 / £95.00 Also available as an eBook
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BioMEMS From MEMS to Bio-MEMS and Bio-NEMS Manufacturing Techniques and Applications Marc J. Madou
University of California, Irvine, USA
This text details manufacturing techniques applicable to bio-nanotechnology. After reviewing MEMS techniques, materials, and modeling, the author covers nanofabrication, genetically engineered proteins, artificial cells, nanochemistry, and self-assembly. He also discusses scaling laws in MEMS and NEMS, actuators, fluidics, and power and brains in miniature devices. He concludes with coverage of various MEMS and NEMS applications. Solutions manual, PowerPoint® lecture slides, and electronic figures available upon qualifying course adoption
Catalog no. 5516X, June 2011, 650 pp. ISBN: 978-1-4200-5516-0, $99.95 / £63.99 Also available as an eBook
Fundamentals of Microfabrication and Nanotechnology Third Edition, Three-Volume Set
Biomedical Microsystems Ellis Meng
University of Southern California, Los Angeles, USA
Written by an active researcher named one of Technology Review’s Young Innovators Under 35, this book begins with an introduction to the benefits of miniaturization. It introduces materials, fabrication technology, and the necessary components of all bioMEMS. The author covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering. Detailed examples, exercises, and illustrations help clarify the concepts. Solutions manual available with qualifying course adoption
Catalog no. 51229, September 2010, 408 pp. ISBN: 978-1-4200-5122-3, $94.95 / £59.99 Also available as an eBook
Catalog no. 3180, August 2011, 1992 pp. ISBN: 978-0-8493-3180-0, $249.95 / £159.00
BioMEMS Science and Engineering Perspectives Simona Badilescu and Muthukumaran Packirisamy Concordia University, Montreal, Canada
Covering often overlooked areas in the field of bioMEMS, this volume spans topics associated with biomolecules and complex biological entities, as well as subjects directly linked to the design, fabrication, and characterization of devices. Unlike other references, this text aids in the fundamental physiochemical understanding of biological processes relevant to the performance of various biosensing devices. Solutions manual available with qualifying course adoption
Catalog no. K10877, April 2011, 368 pp. ISBN: 978-1-4398-1699-8, $99.95 / £63.99 Also available as an eBook
New!
Introduction to BioMEMS Albert Folch
University of Washington, Seattle, USA
“The field has been waiting for a true textbook that provides a practical, historical, authoritative and comprehensive introduction to bioMEMS. It has finally arrived, courtesy of Albert Folch, complete with PowerPoint lectures and thoughtful homework questions. I highly recommend it.” —David J. Beebe, University of Wisconsin–Madison
“A comprehensive, colorful textbook on the important field of bioMEMS.” —Albert van den Berg, University of Twente
“... a monumental achievement ...” —Mehmet Toner, Helen Andrus Benedict Professor of Bioengineering, Harvard Medical School
Catalog no. K10966, August 2012, 528 pp., ISBN: 978-1-4398-1839-8, $89.95 / £57.99 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Biomaterials and Biological Interfaces New!
Coming Soon!
Biomaterials Science
The Medical Device R&D Handbook
An Integrated Clinical and Engineering Approach
Second Edition Edited by
Theodore R. Kucklick TRKD Medical Devices, Los Gatos, California, USA
Edited by
Yitzhak Rosen
New Edition a Bestseller!of
Superior NanoBioSystems, Silver Spring, Maryland, USA
Praise for the First Edition:
Noel Elman
“This is the first in its class of multidisciplinary books for medical device innovators, reaching across several disciplines to capture what innovators need.”
Cambridge, Massachusetts, USA
"… offers a good overview of biomaterials as medical devices, drug delivery and tissue engineering systems. The emphasis is on integrating clinical and engineering approaches. In particular, the book covers various applications of biomaterials in unmet clinical needs in variety of fields … covers areas such as regulatory challenges and commercialization issues." —From the Foreword by Robert Langer, Massachusetts Institute of Technology, Boston, USA
"This book is essential when designing, developing and studying biomedical materials. … provides an excellent review—from a patient, disease, and even genetic point of view—of materials engineering for the biomedical field." —Fanny Raisin-Dadre, BioInteractions Ltd., Berkshire, UK
"The success of current and emerging biomedical technologies centers on multiple factors including device design, host foreign body reaction to the biomaterial, regulatory reviews, market needs, and patient-centered factors such as co-morbidity and underlying pathologies. The later point needs to be further emphasized in biomaterial education and training. This book highlights these critical elements in carefully selected case studies that are relevant and up to date. The advancement of biomaterials and medical devices require a multidisciplinary team approach including clinical insights. Drs. Rosen, Elman, and Horowitz effectively brought these interwoven topics together in this well presented reference book." —W. John Kao, University of Wisconsin–Madison, USA
Rather than approaching biomaterials science from just a materials science and engineering perspective, this book also covers the clinical side. Leading contributors address such topics as hemocompatibility, cellular mechanisms, signal transduction, clinical trials, nanotechnology, FDA regulations, and ethical issues. Catalog no. K10223, June 2012, 310 pp. ISBN: 978-1-4398-0404-9, $149.95 / £95.00 Also available as an eBook
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—Michael Gertner, MD, Co-Director, Surgical Innovation Program at Stanford University
“... a resource that will help medical device innovators develop better products, and more focused companies, more quickly.” —Randy Williams, Founder, The Keiretsu Forum
“Finally, a real manual that for the first time supports efficient medical device development.” —Peter H. Muller, President, Interform Product Development
Written for medical device designers, biomedical engineering students, physician entrepreneurs, and medical device entrepreneurs, this reference explains the basics on how to prototype and develop a medical device. It discusses the basics of plastics, adhesives, medical needles, and rapid prototyping as well as tips and tools to save time and money. This updated and expanded second edition includes practical advice and interviews from key opinion leaders and pioneers in the field. • Explains basics of prototyping medical devices • Provides practical advice and examples from key opinion leaders and pioneers • Offers extensive references at the end of each chapter • Includes tips on time and money saving techniques Selected Contents Medical Plastics. Medical Metals. Medical Adhesives. Specialized Materials. Catheter Forming Operations. Balloon Forming. Catheter Building. Rapid Prototyping. Medical Molding. Medical Illustration. Regulatory Affairs. Needles and Cannulae. In Vitro and In Vivo Studies. Patents and Intellectual Property. Using Industrial Design. ... Catalog no. K10598, December 2012, c. 440 pp. ISBN: 978-1-4398-1189-4, $139.95 / £89.00 Also available as an eBook
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Biomaterials and Biological Interfaces Nanobiomaterials Handbook
New!
Edited by
Szycher's Handbook of Polyurethanes
Balaji Sitharaman
Second Edition
State University of New York at Stony Brook, USA
Nanobiomaterials exhibit distinctive characteristics which make them suitable for a variety of biological applications. This volume provides a comprehensive overview of the field, offering a broad introduction for those new to the subject as well as a useful reference for advanced professionals. Analyzing major topics and disciplines in this arena, the book examines various synthesis and processing techniques important for developing nanobiomaterials, explores their unique nanoscopic physicochemical properties, discusses potential applications, and provides a detailed overview of the interactions between bionanomaterials/biological systems and the biocompatibility issues associated with bionanomaterials. • Surveys the major topics and disciplines underlying the subject of nanobiomaterials • Examines state-of-the-art research and practice around the world • Includes contributions by a team of worldrenowned experts • Presents the unique challenges in the design, fabrication, and evaluation of bionanomaterials from a device-development and applications point of view • Explores the intersection of bionanomaterials with biological systems • Discusses issues related to the biocompatibility of bionanomaterials
Edited by
Michael Szycher, Ph.D "The book can be highly recommended to practitioners." —Polymer News
"... a valuable resource ... brings together information from a wide variety of academic and commercial sources. ... contains a wealth of information from the patent literature which reflects the commercial importance of polyurethanes and provides direction for future research and development activities." —Andrew M. Reed, Ph.D., President, AMRAR, LLC
"... covers all the arms of the polyurethane family. The patent and general references allows further in depth studies to be carried out ..." —Ian Clemitson, Retired Industrial Chemist, Bellmere, Qld, Australia
Catalog no. K11811, July 2012, 1144 pp. ISBN: 978-1-4398-3958-4, $199.95 / £127.00 Also available as an eBook
New!
Polymers for Vascular and Urogenital Applications Edited by
Selected Contents
Shalaby W. Shalaby, Karen J.L. Burg, and Waleed Shalaby
Nanobiomaterials: Current and Future Prospects. Multifunctional Gold Nanoparticles for Cancer Therapy. Synthesis, Processing, and Characterization of Ceramic Nanobiomaterials for Biomedical Applications. Synthesis, Properties, Characterization, and Processing of Polymeric Nanobiomaterials for Biomedical Applications. Carbon-Based Nanomedicine. Synthetic and Toxicological Characteristics of Silica Nanomaterials for Imaging and Drug Delivery Applications. Peptide-Based SelfAssembled Nanofibers for Biomedical Applications. Electrostatically Self-Assembled Nanomaterials. ...
In a carefully crafted, multidisciplinary, skillfully focused format, this book covers attributes of polymers used for vascular, urological, and gynecological materials. It provides a brief analysis of how the use of polymers in vascular and urogenital applications has evolved in the past five decades and outlines their common and specific functional requirements. It features small, readable monographs that provide a description of the evolving role of a particular material, and present topics in highly integrated, well-balanced, authoritatively prepared segments on materials processing and in vitro and in vivo evaluation, complete with case studies.
Catalog no. 94661, June 2011, 737 pp. ISBN: 978-1-4200-9466-4, $169.95 / £108.00 Also available as an eBook
Catalog no. 76949, May 2012, 270 pp. ISBN: 978-1-4200-7694-3, $179.95 / £114.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Biomaterials and Biological Interfaces Coming Soon!
Materials and Processes for Medical Devices Mel Schwartz Written for students and professionals in materials science and biomedical engineering, this book discusses and reviews materials for use in various medical device applications. It covers nanomaterials, composites, shape memory alloys, plastics, ceramics, and ferrous materials. The book also covers chemistry, metallurgy, coatings, thin films, and corrosion. It discusses material properties such as fatigue strength, hardness, and tensile strength. The book covers cutting-edge research including nanotechnology, material selection, processing methods, current and emerging fabrication technologies, software, as well as case histories. Devices and materials currently used in the industry are described and explained by the developers who made them. Catalog no. K11412, November 2012, c. 716 pp. ISBN: 978-1-4398-2875-5, $149.95 / £95.00 Also available as an eBook
Coming Soon!
Bacterial Cellulose
Reliable Design of Medical Devices Third Edition Richard C. Fries
Isorel, Inc., Fitchburg, Wisconsin, USA
The medical device industry is constantly changing; as a result, texts regarding the reliability of these devices must keep pace with changes. With an emphasis on safety and analysis of hazards and risks, this new third edition addresses changes in software methodology and discusses the latest thinking on software reliability. The added material and new discussions provide working engineers with assistance in preparing, designing, and testing a product. Discussions on hazard analysis and tools such as FMEA and FTA provide direction in assuring that the new device is safe and effective. Every chapter has been completely updated and three new chapters have been added. Catalog no. K14218, September 2012, 501 pp. ISBN: 978-1-4398-9491-0, $179.95 / £114.00 Also available as an eBook
Coming Soon!
Advances in Therapeutic Engineering
A Sophisticated Multifunctional Material
Edited by
Edited by
Miguel Gama, Paul Gatenholm, and Dieter Klemm The first book dedicated to the potential applications and unique properties of bacterial cellulose (BC), this seminal work covers the basic science, technology, and economic impact of this bulk chemical as well as the companies and patents that are driving the field. It reviews the biosynthesis and properties of BC, including genetics and characterization; discusses the advancing technology as it relates to product development, bioreactors, and production; and analyzes the economic impact of BC on a diverse range of industry applications, including materials and biomaterials, biological and polymer sciences, and electromechanical engineering. Catalog no. K13216, November 2012, c. 304 pp. ISBN: 978-1-4398-6991-8, $129.95 / £82.00 Also available as an eBook
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New!
Wenwei Yue, Subhagata Chattopadhyay, Teik-Cheng Lim, and Rajendra Acharya This comprehensive, edited book brings together topics in therapeutic and rehabilitative engineering, ranging from prosthetics to sensory substitution and medical robotics. Drawing on the expertise of a multidisciplinary field of contributors, it discusses both diagnostic and therapeutic aspects of health care and rehabilitation, including healthcare informatics, biomedical signal processing, sensors, and robotic prosthetics. Presenting a system-level approach to therapeutic engineering, it explores the current state and future directions of this rapidly advancing and cutting-edge field. Catalog no. K13287, December 2012, c. 456 pp. ISBN: 978-1-4398-7173-7, $179.95 / £109.00 Also available as an eBook
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Biomaterials and Biological Interfaces Textbooks for Your Lectures and Lab Courses
An Introduction to Biomaterials Second Edition Edited by
Jeffrey O. Hollinger
Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
The second edition of this popular text includes nine new chapters that provide a comprehensive and up-to-date educational framework for biomaterials education. A new chapter on the biology of wound healing sets the stage for the basic requirements of standardized biomaterials testing and explains the reactions between biomaterials and the living system into which it is implanted. The book explains in vitro and in vivo testing paradigms and provides numerous examples in the chapters on experimental design, laboratory assays, and animal models. Emphasizing the importance of the regulatory process, it describes how innovation in biomaterials relates to patentability and inventorship. • Covers wound healing biology and host response to implanted biomaterials • Examines the regulatory process, including standardized product testing • Reviews the innovativeness of biomaterials, with inventorship and patents in mind • Considers experimental design, basic scientific methods, and statistics • Includes extensive references for further study • Contains end-of-chapter questions and answers Solutions manual available with qualifying course adoption
Selected Contents Consensus Definitions, Fundamental Concepts, and a Standardized Approach to Applied Biomaterials Sciences Biology, Biomechanics, Biomaterial Interactions: Wound Healing Biology Biology, Biomechanics, Biomaterial Interactions: Cellular Mechanics Biology, Biomechanics, Biomaterial Interactions: Materials–Host Interactions Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property: Standardized Materials Testing Catalog no. K10637, November 2011, 644 pp. ISBN: 978-1-4398-1256-3, $119.95 / £48.99 Also available as an eBook
A Laboratory Course in Biomaterials Wujing Xian
University of Illinois at Urbana-Champaign, USA
A teaching tool for instructors in biomaterials and bioengineering, this volume is a comprehensive laboratory textbook. It trains readers in laboratory skills, data analysis, problem solving, and scientific writing. It integrates a variety of principles that include materials science, chemistry, biochemistry, molecular and cell biology, and engineering. Providing detailed descriptions, explanations, and illustrations of experiments, the text also includes a series of questions and answers at the end of each chapter to clarify concepts. Many of the experiments presented are adapted from research papers to reflect the recent progress in biomaterials and bioengineering. • Presents detailed, step-by-step descriptions of lab procedures and explanations for the underlying principles • Contains user-friendly graphic illustrations for the experiments • Provides a series of questions and answers at the end of each chapter to clarify concepts and induce critical thinking • Includes text boxes with in-depth information, case studies, and lab tips • Offers information on equipment, reagents, and supplies for instructors Selected Contents Basic Laboratory Skills. Module I. Drug Delivery: Controlled Release of Encapsulated Protein from PLGA Microspheres. Module II. Natural Biomaterials: Collagen and Chitosan. Basic Laboratory Skills II. Cell Culture and Microscopy. Module III. Biocompatibility Testing: Cytotoxicity and Adhesion. Module IV. Tissue Engineering: Organotypic Cultures of Skin Equivalents. Module V. Bioceramics: Porous Hydroxyapatite Composite. Appendix: Answers. Index. Catalog no. 75829, June 2009, 216 pp. Soft Cover, ISBN: 978-1-4200-7582-3 $64.95 / £41.99
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Biomaterials and Biological Interfaces
ISO 13485
Biological and Biomedical Coatings Handbook Two-Volume Set Edited by
Sam Zhang Nanyang Technological University, Singapore
Important in today’s nanotechnology, biological and biomedical coatings have been studied extensively and are receiving much attention from researchers. A timely reference for both experts and newcomers, this handbook explores the latest developments in films and coatings for biological and biomedical applications. The text covers a wide array of material types, including sol-gel, bio-ceramics, polymers, glass, nanomaterials, and chitosan. It also addresses various processes for developing and implementing these coatings, including CVD and PVD, drug delivery, released-control coatings, and spectroscopy. • Presents cutting-edge developments from world leaders in films and coatings research • Covers processing, properties, and performance • Discusses sol-gels, bio-ceramics, polymers, glasses, nanomaterials, and other materials • Explores CVD and PVD • Includes information on drug delivery and released-control coatings • Serves as a simplified introductory stepping stone for new entrants to the field • Gives experts up-to-date figures, tables, plots, and images to aid their own work Catalog no. K11126, May 2011, 976 pp. ISBN: 978-1-4398-2125-1, $249.95 / £159.00 Also available as an eBook
Also available as individual volumes Processing and Characterization Catalog no. K12269, May 2011, 456 pp. ISBN: 978-1-4398-4995-8, $139.95 / £89.00 Also available as an eBook
Applications
Catalog no. K12270, May 2011, 520 pp. ISBN: 978-1-4398-4996-5, $139.95 / £89.00 Also available as an eBook
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A Complete Guide to Quality Management in the Medical Device Industry Itay Abuhav
Hinterforst, Switzerland
The United States and European Union now require the ISO 13485 Standard certification for medical device manufacturers. Written by an experienced industry professional, this practical book provides a complete guide to the ISO 13485 Standard certification for medical device manufacturing in terms of quality control. It covers all the requirements of ISO 13485 and offers a step-by-step comparison between the ISO 13485 and ISO 9001, enabling a sound understanding of these new procedures. Catalog no. K12946, October 2011, 374 pp. ISBN: 978-1-4398-6611-5, $129.95 / £82.00 Also available as an eBook
New!
Materials in Biology and Medicine Edited by
Sunggyu Lee
Ohio University, Athens, USA
David Henthorn
St. Louis University, Missouri, USA
"… a timely addition to the field … cutting-edge articles by leading experts review critical areas covering biomaterials and biomimetic materials, materials function and response modification, and medical device development. Each application-oriented chapter provides the relevant scientific and engineering background with extensive references for further study and research. The contributors use multiple examples to provide rich insights into a broad array of biomaterial applications for a target audience consisting of graduate students, materials scientists, research engineers, and academic physicians and surgeons." —Dr. Sunil K. Kesavan, Akebono Inc. Farmington Hills, Michigan, USA
Catalog no. K13848, March 2012, 260 pp. ISBN: 978-1-4398-8169-9, $169.95 / £108.00 Also available as an eBook
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Biomaterials and Biological Interfaces Chitosan-Based Hydrogels Biomimetics Nature-Based Innovation Yoseph Bar-Cohen JPL/Caltech, Pasadena, California, USA
A review of the current state of the art of biomimetics, this book documents key biological solutions that provide a model for innovations in engineering and science. Leading experts explore a wide range of topics, including artificial senses and organs; mimicry at the cell–materials interface; modeling of plant cell wall architecture; biomimetic composites; artificial muscles; biomimetic optics; and the mimicking of birds, insects, and marine biology. The book also discusses applications of biomimetics in manufacturing, products, medicine, and robotics; biologically inspired design as a tool for interdisciplinary education; and the biomimetic process in artistic creation. Catalog no. K11566, September 2011, 788 pp. ISBN: 978-1-4398-3476-3, $159.95 / £99.00 Also available as an eBook
Materials Science of DNA Edited by
Jung-II Jin
Korea University, Seoul, South Korea
James Grote
AFRL/RXPS, Wright Patterson Air Force Base, Ohio, USA
Functions and Applications Edited by
Kangde Yao, Junjie Li, Fanglian Yao, and Yuji Yin Tianjin University, People's Republic of China
This work details the latest progress in the research and development of chitosan-based biomaterials, providing the foundation for future research. The book introduces the formation and chemical structure of chitosan-based hydrogels. It also discusses the relationship between their structure and functions, which provides a theoretical basis for the design of biomaterials. In addition, many real-world examples illustrate the potential application of chitosan-based hydrogels in various fields, including materials science, biotechnology, pharmaceuticals, regenerative medicine, and cell engineering. Catalog no. K11120, July 2011, 521 pp. ISBN: 978-1-4398-2114-5, $189.95 / £121.00 Also available as an eBook
Design of Biomedical Devices and Systems Second Edition Paul H. King
Vanderbilt University, Nashville, Tennessee, USA
Richard C. Fries
As interest continues to grow, DNA is expected to become focal to nanobiotechnology because of its structural and chemical characteristics. With chapters written by experts in their respective fields, this text chiefly focuses on the rapidly growing fields of nanoscience, nanotechnology, and biotechnology. It is the first to address the materials science facet of DNA, rather than its chemical, biochemical, or biological aspects. It includes tables, graphs, equations, and an ancillary CD-ROM to provide understanding of DNA and the great potential of this biopolymer as advanced material.
Isorel, Inc., Fitchburg, Wisconsin, USA
Catalog no. K11352, December 2011, 338 pp. ISBN: 978-1-4398-2741-3, $119.95 / £76.99 Also available as an eBook
Catalog no. 61798, August 2008, 424 pp. ISBN: 978-1-4200-6179-6, $129.95 / £82.99 Also available as an eBook
The second edition of a bestseller, this book provides a comprehensive overview of biomedical device and system design—including topics related to databases, process analysis, and device improvement—from a strong design perspective. It covers all aspects of design that must be considered for complex biomedical projects. This second edition features information on device definition and reliability, as well as testing and hardware verification and each chapter has been updated to reflect the latest advances in the field.
For more information and complete contents, visit www.crcpress.com
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Biomaterials and Biological Interfaces Designing Usability into Medical Products
Biomaterials Fabrication and Processing Handbook
Michael E. Wiklund
Edited by
Wiklund Research & Design, Inc., Concord, Massachusetts, USA
Stephen B. Wilcox
Paul K. Chu
City University of Hong Kong, Kowloon
Design Science, Philadelphia, Pennsylvania, USA
Xuanyong Liu
"This book should be on the shelf of anyone involved in the development of medical products. Today devices are getting more and more complex while caregivers as a whole are much less experienced. User centered interface design has to make up the difference and this book gives you a plan."
Comprehensive in scope, this volume focuses on a variety of production and processing aspects of the latest biomaterials. It discusses how scaffolds are used in tissue engineering and describes common implant materials, such as hard tissue, blood-contacting, and soft tissue. The book also examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bio-MEMS. With contributions from renowned international experts and extensive reference lists in each chapter, this book provides detailed, practical guidance on producing biomaterials and employing them in biomedicine.
—Nicholas Barker, Vice President - Design, Datascope Corp
Advocating a user-centered approach to medical technology design, this book covers the essential processes and specific techniques necessary to produce safe, effective, usable, and appealing medical systems and products. Catalog no. 2843, February 2005, 376 pp. ISBN: 978-0-8493-2843-5, $139.95 / £89.00 Also available as an eBook
Shanghai Institute of Ceramics, China
Catalog no. 7973, March 2008, 720 pp. ISBN: 978-0-8493-7973-4, $169.95 / £108.00 Also available as an eBook
Biomaterials
Biomaterials A Nano Approach
Joyce Y. Wong
Seeram Ramakrishna, Murugan Ramalingam, T.S. Sampath Kumar, and Winston O. Soboyejo
Joseph D. Bronzino
From a multi-disciplinary point of view, this book examines basic concepts, various processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications. It spans their historical development and reviews recent advances in the field. It describes how basic concepts in nanotechnology are applied to the processing of novel nanobiomaterials, including nanostructured metals and alloys. Presenting illustrative examples and a variety of applications, this text offers a solid framework for understanding present and future trends of biomaterials in human health care systems. Catalog no. 47817, June 2010, 372 pp. ISBN: 978-1-4200-4781-3, $99.95 / £69.99
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Boston University, Massachusetts, USA Trinity College, Hartford, Connecticut, USA
To make sure medical devices placed inside the body are safe, reliable, economical, and biologically and physiologically compatible, the modern biomedical engineer must have a broad knowledge of currently available materials and the properties that affect their in-service performance. In chapters drawn from the third edition of the bestselling Biomedical Engineering Handbook, Biomaterials surveys the wide variety of biomaterials in present use as well as materials resulting from novel micro- and nanoscale technologies. Catalog no. 7888, June 2007, 296 pp. ISBN: 978-0-8493-7888-1, $104.95 / £66.99 Also available as an eBook
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Biomaterials and Biological Interfaces Coming Soon! Coming Soon!
Corrosion of Ceramic Materials Third Edition Ronald A. McCauley
Rutgers, The State University of New Jersey, Piscataway, USA
Catalog no. K11066, December 2012, c. 432 pp. ISBN: 978-1-4398-2022-3, $159.95 / £99.00 Also available as an eBook
Advances in the Engineering of Polysaccharide Materials by PhosphorylaseCatalyzed Enzymatic Chain-Elongation Jun-ichi Kadokawa and Yoshiro Kaneko Kagoshima University, Japan
Catalog no. N10553, December 2012, c. 200 pp. ISBN: 978-981-4364-45-4, $129.95 / £82.00 Also available as an eBook
Ultrasonic and Electromagnetic NDE for Structure and Material Characterization
New!
Engineering and Biomedical Applications
Giuseppe Pezzotti
Edited by
Tribikram Kundu
The University of Arizona, Tucson, USA
Advanced Materials for Joint Implants Kyoto Institute of Technology, Japan
Catalog no. N10574, August 2012, 400 pp. ISBN: 978-981-4316-88-0, $179.95 / £114.00 Also available as an eBook
Catalog no. K11655, June 2012, 890 pp. ISBN: 978-1-4398-3663-7, $149.95 / £95.00 Also available as an eBook
New!
Bionanomaterials for Dental Applications Edited by
Mieczyslaw Jurczyk
Multiporphyrin Arrays Fundamentals and Applications Edited by
Dongho Kim
Poznan University of Technology, Poland
Institute for NanoBio Molecular Assemblies, Seoul, South Korea
Catalog no. N10474, August 2012, 350 pp. ISBN: 978-981-4303-83-5, $149.95 / £95.00 Also available as an eBook
Catalog no. N10500, January 2012, 828 pp. ISBN: 978-981-4316-60-6, $249.95 / £159.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Cell & Tissue Engineering Textbooks for Your Lectures and Lab Courses
Coming Soon!
Tissue Engineering Principles and Practices
A Laboratory Course in Tissue Engineering Melissa Kurtis Micou University of California, San Diego, USA
Johh P. Fisher
University of Maryland, Kensington, USA
Dawn Kilkenny
University of Toronto, Ontario, Canada
Antonios G. Mikos
Rice University, Houston, Texas, USA
Joseph D. Bronzino
Simsbury, Connecticut, USA
Donald R. Peterson
University of Connecticut, Farmington, USA
With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nonobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage and dental tissue engineering, and vascular and neural engineering. It provides a comprehensive overview of major research topics in tissue engineering. • Includes contributions from experts and pioneers • Covers emerging topics such as regenerative medicine • Discusses the impact of tissue engineering products could have on the future of medicine Selected Contents Fundamentals: Strategic Directions. Calcium Phosphates. Protein Based Biomaterials. Synthetic Biomaterials. Morphogens. Signal Expression. Embryonic Stem Cells. Hematopoietic Stem Cells. Mesenchymal Stem Cells. Enabling Technologies: Nanobiomaterials. Biomimetics. Molecular Biology Techniques. Biomaterial Mechanics. Mechanical Conditioning. Micropatterned Surfaces. Drug Delivery. Gene Therapy. Cell Engineering. Cell Encapsulation. Cocultures. Bioreactors. Shear Forces. Vascularization. Bioimaging. Modeling. Applications: Bone Engineering. Craniofacial Engineering. Tendon & Ligament Engineering. Cartilage Tissue Engineering. TMJ Engineering. ... Catalog no. K13429, December 2012, c. 768 pp. ISBN: 978-1-4398-7400-4, $149.95 / £95.00 Also available as an eBook
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New!
"The book is well-organized to teach cell culture and tissue engineering experiments to novice and experienced students. There is a quantitative emphasis in the book that strengthens the ‘engineering’ part of tissue engineering." —Ann Saterbak, Rice University, Houston, Texas, USA
A hands-on lab manual for tissue engineering instruction, this book contains 15 standalone experiments based on both classic and modern approaches. Experiments encompass a set of widely applicable techniques: cell culture, microscopy, histology, immunohistochemistry, mechanical testing, soft lithography, and common biochemical assays. In addition to these specific techniques, the experiments emphasize engineering analysis, mathematical modeling, and statistical experimental design. • Contains fifteen stand-alone experiments, allowing instructors to customize their courses • Presents experiments using equipment commonly found in labs equipped for tissue culture and minimizing the cost of reagents • Includes prelab and postlab questions for each experiment • Emphasizes engineering analysis, mathematical modeling, and statistical design of experiments • Describes multiple formats useful for the presentation of results, including technical posters, extended abstracts, and technical reports • Includes more than 70 illustrations Solutions manual available with qualifying course adoption
Selected Contents Getting Started in the Lab. Lab Safety. Essential Lab Skills for Tissue Engineers. Isolation of Primary Chondrocytes from Bovine Articular Cartilage. Measuring and Modeling Growth of a Cell Population. ... Catalog no. K13694, August 2012, 304 pp. Soft Cover, ISBN: 978-1-4398-7893-4 $59.95 / £38.99 Also available as an eBook
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Cell & Tissue Engineering Coming Soon!
New!
Tissue Engineering and Regenerative Medicine
Biomaterials and Stem Cells in Regenerative Medicine
A Nano Approach
Murugan Ramalingam
Edited by
Edited by University of Strasbourg, France
Murugan Ramalingam
Seeram Ramakrishna
Pekka Vallittu
Serena Best
Ugo Ripamonti
This book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It explores key scientific and clinical aspects, including the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications. The text bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for multidisciplinary biomedical research.
University of Strasbourg, France University of Turku, Finland University of Witwatersand, Parktown, South Africa
Wan-Ju Li
University of Wisconsin, Madison, USA
This book bridges the gap between nanotechnology and regenerative medicine to facilitate their transition from lab to the clinic. It compiles important aspects of the basic science and fundamental principles to current nanotechnological innovations in biomaterials, cell, tissue, and organ engineering, and their clinical relevance, as well as future trends in regenerative medicine. It is intended for a wide audience including students, researchers, professors, and industrial experts working in the tields of biomaterial science and engineering, nanoscience and nanotechnology, bioengineering, cell biology, biomedical sciences, tissue engineering, and nanomedicine. • Provides a self-contained book for understanding the current perspectives and nanotechnological advances on tissue engineering and regenerative medicine • Offers extensive coverage of a range of biomaterials, cells, and their interaction for the development of tissues and organs in the context of regenerative medicine • Provides vision for global healthcare systems at the nanoscale level • Supplies integrated approach to the organization of nanotechnology, biomaterials, bioengineering, and biomedical sciences in the form of multidisciplinary program • Incorporates useful figures and tables with current technical/clinical data
National University of Singapore, Singapore University of Cambridge, UK
• Provides a self-contained resource for understanding the current perspectives on biomaterials and stem cells in regenerative medicine • Offers extensive coverage of a range of biomaterials and their interaction with stem cells and other cellular elements • Covers different length scales, including macro, micro, nano, and molecular • Supplies an integrated, multidisciplinary approach to biomedical research, bridging the gap among materials science and engineering, micro- and nanotechnology, bioengineering, and biomedical sciences • Incorporates useful figures and tables with current data Selected Contents
Nanobiomaterials An Overview. Cells and Nanobiomaterial Interaction. Biomechanics of Cells and Tissues. ...
Identification and Application of Polymers as Biomaterials for Tissue Engineering and Regenerative Medicine. Hydrogel as Stem Cell Niche for In Vivo Applications in Regenerative Medicine. Fabrication and Application of Gradient Hydrogels in Cell and Tissue Engineering. Smart Biomaterial Scaffold for In Situ Tissue Regeneration. Fabrication of 3D Scaffolds and Organ Printing for Tissue Regeneration. ...
Catalog no. K13868, October 2012, c. 600 pp. ISBN: 978-1-4398-8185-9, $149.95 / £95.00 Also available as an eBook
Catalog no. K13711, July 2012, 564 pp. ISBN: 978-1-4398-7925-2, $149.95 / £95.00 Also available as an eBook
Selected Contents
For more information and complete contents, visit www.crcpress.com
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Cell & Tissue Engineering Stem Cells and Revascularization Therapies
Coming Soon!
Edited by
Principles and Practices
Hyunjoon Kong and Lawrence B. Schook
Stem Cell Engineering Edited by
University of Illinois UrbanaChampaign, USA
Andrew J. Putnam
David Schaffer
University of California, Berkeley, USA
University of California, Irvine, USA
Joseph D. Bronzino
In the last few decades, significant advancements in the biology and engineering of stem cells have enabled progress in their clinical application to revascularization therapies. Some strategies involve the mobilization of endogenous stem cell populations, and others employ cell transplantation. As a result, both techniques have benefited from multidisciplinary efforts to create biomaterials and other biomedical tools that can improve and control the fate of stem cells, and advance our understanding of them.
Donald R. Peterson
Simsbury, Connecticut, USA
• Explores how to define, isolate, and characterize various stem and progenitor cell populations for neovascularization • Summarizes some especially useful model systems and approaches used to regulate angiogenesis, vasculogenesis, and arteriogenesis, and explores their impact on formation of functional vessels in vivo • Focuses on stem cell homing to sites of injury and inflammation, and strategies to exploit this mobilization phenomenon • Covers stem cell transplantation topics, including recreating features of endogenous stem cell niches to maintain the multipotency of transplanted cells and combinatorial delivery of cells and molecular factors Selected Contents Stem Cell Isolation and Purification Technologies In vitro Stem Cell Culture Technologies Stem Cell Mobilization Strategies Stem Cell Transplantation Strategies Catalog no. K10180, December 2011, 342 pp. ISBN: 978-1-4398-0323-3, $149.95 / £95.00 Also available as an eBook
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University of Connecticut, Farmington, USA
With contributions from pioneers and experts, this book provides a broad overview of the challenges of stem cell engineering. It discusses advances made during the last decade that have led to increasingly defined culture systems for growing human ES cells, starting from co-culture with feeder cells in the presence of serum to growth on synthetic substrates in defined medium. The book highlights recent advances in the understanding of the cellular and molecular composition of the hematopoietic stem cell niche, as well as approaches to build upon this basic information to direct stem cell differentiation into blood cell lineages. • Covers the temporal evolution of cell differentiation state and overall tissue structure in the early developing embryo as well as some parallels with embryonic stem cell differentiation within embryoid bodies • Discusses how mechanical cues regulate cellular processes such as proliferation and migration, as well as highlight parallels for how what has been learned about the mechanobiology of tumors can be applied to stem cells. • Describes recent efforts to develop culture systems that can support the indefinite expansion of human embryonic stem cells, potentially by emulating the microenvironment that pluripotent cells experience during their brief window of existence in early embryogenesis. • Details a number of important considerations in the application of stem cell therapies to the central nervous system • Provides an in-depth analysis of the design of stem cell based cardiac therapies, as well as natural and synthetic biomaterials for the differentiation and importantly for the implantation of cells to enhance their viability and engraftment Catalog no. K13309, November 2012, c. 224 pp. ISBN: 978-1-4398-7204-8, $99.95 / £63.99 Also available as an eBook
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Cell & Tissue Engineering
Nanyang Technology University, Singapore
The Physiology of Bioelectricity in Development, Tissue Regeneration and Cancer
Herbert J. Meiselman
Edited by
Red Blood Cell Aggregation Oguz Baskurt
Koc University, Turkey
Björn Neu
University of Southern California, Los Angeles, USA
Red blood cell (RBC) aggregation, a normally occurring phenomenon and a major factor affecting blood rheology, is an important area of study within bioengineering. This volume is the first to comprehensively review the topic. It provides extensive coverage of the determinants and mechanisms of RBC aggregation. It also examines methods to measure and modify RBC aggregation and discusses comparative data in other mammals. Written by leading researchers, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells. • Provides extensive coverage of the basic mechanisms of RBC aggregation and supporting experimental evidence • Covers the in vivo hemodynamic mechanisms influenced by RBC aggregation, including pathophysiological and clinical consequences • Presents methods to measure RBC aggregation for research and clinical purposes • Describes experimental methods to modify RBC aggregation (in vitro and in vivo) and related hemodynamic methodology • Discusses comparative data on RBC aggregation and related evolutionary concepts • Contains more than 150 illustrations • Includes extensive references at the end of each chapter for additional study Selected Contents Introduction. Determinants of Red Blood Cell Aggregation. Mechanism of Red Blood Cell Aggregation. Measurement of Red Blood Cell Aggregation. Effect of Red Blood Cell Aggregation on In Vitro Blood Rheology. Effect of Red Blood Cell Aggregation on Tube Flow. In Vivo Hemodynamics and Red Blood Cell Aggregation. Alterations in Red Blood Cell Aggregation. Comparative Aspects of Red Blood Cell Aggregation. Index. Catalog no. K11945, September 2011, 318 pp. ISBN: 978-1-4398-4180-8, $119.95 / £82.00 Also available as an eBook
Christine E. Pullar
University of Leicester, UK
Exploring their role in the physiology of development and wound repair and pathophysiologies, such as cancer, this book describes the importance of biological electric fields and their use as tools to influence tissue repair, regeneration, and cancer. The text considers the generation and measurement of these fields, intercellular communication regarding local electrical guidance cues, and the role of bioelectricity in tissue development, regeneration, wound repair, and cancer. Catalog no. K11686, March 2011, 342 pp. ISBN: 978-1-4398-3723-8, $119.95 / £76.99 Also available as an eBook
3D Cell-Based Biosensors in Drug Discovery Programs Microtissue Engineering for High Throughput Screening William S. Kisaalita
University of Georgia, Athens, USA
Written by one of the foremost experts in this field, this book provides the latest information— from theory to practice—on challenges and opportunities for incorporating 3D cell-based biosensors or assays in drug discovery programs. It supplies a historical perspective and defines the problem 3D cultures can solve. It also discusses how genomics and combinatorial chemistry have changed the way drug are discovered and presents data from the literature to underscore the less-than-desirable pharmaceutical industry performance under the new paradigm. Catalog no. 73494, June 2010, 404 pp. ISBN: 978-1-4200-7349-2, $135.95 / £87.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Cell & Tissue Engineering Nanotechnology in Tissue Engineering and Regenerative Medicine Edited by
The Metabolic Pathway Engineering Handbook Two-Volume Set
Ketul Popat
Colorado State University, Fort Collins, USA
Christina Smolke
Referred to as "nanomedicine" or "nanobiomedicine," the application of nanotechnology to medicine can impact diagnosis, monitoring, and treatment of diseases, as well as the control and understanding of biological systems. Bringing together an unparalleled field of experts, this volume explores various aspects of nanotechnology and its applications in biomedical fields. The book uses an application-oriented approach to relate laboratory-based research to the development of technologies that are easily adaptable to an industry environment, focusing chiefly on drug delivery, tissue engineering, and regenerative medicine.
Christina Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer’s yeast, is regarded as one of the brilliant new minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metabolic pathway engineering. With a wealth of cutting-edge material, this work is an invaluable resource for those seeking to add their own contributions. Organized by topic, this reference is available as two volumes that can be purchased individually or as a set. • Presents a thorough and complete overview of the burgeoning field of metabolic pathway engineering • Focuses on the future areas of metabolic engineering and the impact of new technologies • Contains extensive references in each chapter • Features contributions from well-established experts in various subfields of metabolic engineering
Catalog no. K10090, November 2010, 302 pp. ISBN: 978-1-4398-0141-3, $125.95 / £80.99 Also available as an eBook
New!
Optical Imaging Techniques in Cell Biology Second Edition Guy Cox
University of Sydney, New South Wales, Australia
Praise for the First Edition “… represents an excellent resource for those wishing to gain a grounding in a broad range of optical techniques … written in a highly knowledgeable, enthusiastic and accessible manner … comprehensively covers virtually the entire field of microscopy. … a valuable addition to the bookshelf of many research laboratories … can quickly and easily provide a clear understanding of commonly used techniques and underlying concepts. Students, technicians, and researchers will find it useful ...” —Mark Prescott, Department of Biochemistry and Molecular Biology, Monash University, in Australian Biochemist
Catalog no. K12150, June 2012, 316 pp. ISBN: 978-1-4398-4825-8, $149.95 / £95.00 Also available as an eBook
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Stanford University, California, USA
Catalog no. 3923, August 2009, 1259 pp. ISBN: 978-0-8493-3923-3, $269.95 / £165.00 Also available as an eBook
Also available as individual volumes
Fundamentals Edited by
Christina Smolke
Stanford University, California, USA
Catalog no. K10164, July 2009, 678 pp. ISBN: 978-1-4398-0296-0, $174.95 / £112.00 Also available as an eBook
Tools and Applications Edited by
Christina Smolke
Stanford University, California, USA
Catalog no. 77651, July 2009, 581 pp. ISBN: 978-1-4200-7765-0, $174.95 / £112.00 Also available as an eBook
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Cell & Tissue Engineering Nanotechnology and Tissue Engineering The Scaffold Edited by
Cato T. Laurencin University of Virginia, Charlottesville, USA
Coming Soon!
Handbook of Therapeutic Biomarkers in Cancer Edited by
Lakshmi S. Nair
Sherry X. Yang and Janet E. Dancey
With chapters written by world-famous researchers involved with various facets of nanostructured scaffolds, this is the first resource that brings together research and background information on a complete range of engineering processes that have led to the development of a number of highly useful tissues. It details the fundamental and advanced aspects of nanofabrication and includes an examination of cellular interactions at the nanoscale level. The book also discusses clinical implications and applications, making it a critical resource for clinicians, engineers, and other scientists seeking to advance the field.
Catalog no. N10578, December 2012, c. 450 pp. ISBN: 978-981-4364-65-2, $179.95 / £114.00 Also available as an eBook
University of Connecticut, Farmington, USA
Catalog no. 51822, June 2008, 384 pp. ISBN: 978-1-4200-5182-7, $169.95 / £108.00 Also available as an eBook
New!
Regenerative Medicine, Stem Cells and the Liver
This book provides an in-depth description of biomarkers across a broad area of cancer research and oncology with a wealth of information to specific therapies. The focus of each chapter is on a class of targeted and chemotherapy agents, established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions. The book serves as a handbook for use by health professionals and scientists on current applicable biomarkers in oncology.
Handbook of Intelligent Scaffold for Tissue Engineering and Regenerative Medicine Edited by
Gilson Khang
When the liver is overwhelmed by insulting stimuli or is chronically damaged, its regenerative capability is substantially reduced or lost. Researchers have been working together to find solutions to cure failing human liver function. Given the ability of stem cells to self-renew and differentiate into specialized cell liver types, they represent an attractive strategy to replace lost liver function. The book begins by outlining the complex nature of human liver disease and then examines the potential that stem cell based approaches have to offer.
Providing detailed knowledge about fullerene nanowhiskers and the related low-dimensional fullerene nanomaterials, this book introduces tubular nanofibers made of fullerenes, "fullerene nanotubes," as well as the single crystalline thin film made of C60, called "fullerene nanosheet." It is the first publication featuring the fullerene nanowhiskers made of C60, C70, and C60 derivatives and so forth. It demonstrates the synthetic method (liquid–liquid interfacial precipitation method) and the physical and chemical properties such as electrical, mechanical, optical, magnetic, thermodynamic, and surface properties for the fullerene nanowhiskers, including their electronic device application.
Catalog no. N10558, April 2012, 200 pp. ISBN: 978-1-57808-739-6, $99.95 / £63.99 Also available as an eBook
Catalog no. N10464, February 2012, 974 pp. ISBN: 978-981-4267-85-4, $499.95 / £318.00 Also available as an eBook
David C. Hay
MRC Centre for Regenerative Medicine, University of Edinburgh, UK
For more information and complete contents, visit www.crcpress.com
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Biomechanics Coming Soon!
Coming Soon!
Biomechanics of Human Motion
Orthopaedic Biomechanics
Applications in the Martial Arts Emeric Arus
Beth A. Winkelstein University of Pennsylvania, Philadelphia, USA
International Sendo-Ryu Karatedo Federation, Astoria, New York, USA
This book provides an overview of human motion studies (biomechanics) using martial arts as extensive examples and references to fundamental theory. It covers in-depth the anatomical foundation of biomechanics, the biomechanical and physiological foundation of human motion, and fundamentals of biomechanics. The book begins with musculoskeletal anatomy of the most important muscles and their functions. The author describes the biomechanical and physiological foundations of human motion. He covers kinematics and kinetics—the core of biomechanics—and includes examples for martial arts and sports activities that emphasize the concepts described. • Examines biomechanics and human motion studies through the lens of martial arts • Includes examples from a number of different schools such as judo and karate • Emphasizes sports biomechanics • Contains end-of-chapter problems and extensive references Selected Contents The Anatomical Foundations of Biomechanics: Introduction. The Anatomy of Human Motion. Functional Anatomy and Biomechanics. The Biomechanical and Physiological: Foundations of Human Motion. The Concept of Muscular Mechanics. Movement Control (Muscular Physiology). The Fundamentals of Biomechanics: Kinematics in Linear Motion. Kinematics in Angular Motion. Kinetics in Linear Motion. Kinetics in Angular Motion. Martial Arts Biomechanics: The Biomechanics of Throwing Arts. The Biomechanics of Striking, Kicking Arts. The Defense and Attack on Vital Points (Kyusho). Fingers Manipulation. The Biomechanics of the Sword Art. Catalog no. K15991, December 2012, c. 480 pp. Soft Cover, ISBN: 978-1-4665-6323-0 $79.95 / £49.99 Also available as an eBook
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Edited by
This book presents state-ofthe-art developments in orthopedic biomechanics across tissues in the musculoskeletal system at all size scales and with direct relevance to engineering and clinical applications. Discussing the relationship between mechanical loading, function, and biological performance, it first reviews basic structure-function relationships for most major orthopedic tissue types followed by the most-relevant structures of the body. It then addresses multiscale modeling and biologic considerations. It concludes with a look at applications of biomechanics, focusing on recent advances in theory, technology and applied engineering approaches. • Presents state-of-the-art findings and techniques of orthopedic biomechanics • Integrates basic biomechanics and clinical-relevant applications • Covers the entire body, addressing issues across several tissues and anatomic structures • Includes applications of biomechanics Selected Contents Structure and Function of Orthopaedic Tissues: Bone Biomechanics. Tendon and Ligament Biomechanics. Intervertebral Disc Cell Mechanics and Mechanobiology. Multiscale Perspective on Structure, Mechanics, and Function of Skeletal Muscle. Musculoskeletal Structures: Skull Biomechanics. Temporomandibular Joint: Structure, Function, and Current Perspectives. Spine Biomechanics. Joint Mechanics of the Shoulder. Biomechanics of Wrist and Hand. Lower Limb Structure, Function, and Locomotion Biomechanics. Biologic Considerations and Clinically Related Orthopedic Biomechanics: Musculoskeletal Cell Mechanics. Biomechanics of Musculoskeletal System Growth and Development. Gender and Aging: Considerations for Orthopedics. Computational Approaches to Studying Normal and Pathological Mechanobiology of Whole Joints and Their Tissues. Clinical Gait Analysis. Injury Biomechanics. ... Catalog no. K12804, December 2012, c. 632 pp. ISBN: 978-1-4398-6093-9, $179.95 / £114.00 Also available as an eBook
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Biomechanics Biofluid Mechanics The Human Circulation, Second Edition Krishnan B. Chandran
Mechanobiology Handbook
University of Iowa, Iowa City, USA
Edited by
Stanley E. Rittgers
Jiro Nagatomi
University of Akron, Ohio, USA
Ajit P. Yoganathan
Georgia Institute of Technology, Atlanta, USA
“... the book provides a good platform in fluid mechanics prior to progressing to the physiological applications which make it an appropriate textbook for BME students.” —Professor Tim McGloughlin, Centre for Applied Biomedical Engineering Research and Department of Mechanical Aeronautical and Biomedical Engineering, University of Limerick
This classroom-tested text teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition includes improved figures, additional examples, and more problems at the end of each chapter. It also presents a new chapter on the computational fluid dynamic analysis of the human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas. • Provides a classroom-tested textbook for a first course on fluid mechanics in human circulation, focusing on the heart and major arteries • Reviews fluid and solid mechanics and normal cardiovascular physiology • Explains how to model steady and unsteady flows • Evaluates the design and development of artificial heart valves, stent implants, and vascular grafts • Describes various considerations and approaches involved in the computational modeling of cardiovascular diseases and therapies Includes end-of-chapter references and problems as well as numerous figures selected from the publications of many eminent researchers Solutions manual available with qualifying course adoption
Catalog no. K12006, February 2012, 451 pp. ISBN: 978-1-4398-4516-5, $104.95 / £66.99 Also available as an eBook
Clemson University, South Carolina, USA
At appropriate levels, mechanical stimuli are necessary for growth and maintenance of healthy tissues and organs. Mechanobiology examines effects of mechanical force stimuli on cellular biological functions. The past two decades have seen a dramatic increase in the level of research in mechanobiology. Collecting the cutting-edge research findings from a diverse range of scientists, the Mechanobiology Handbook presents basic materials in mechanics and cell biology. It is a reference for those new to the field and is designed to stimulate new ways of thinking in current mechanobiology researchers. • Presents research data and viewpoints from diverse fields of mechanobiology • Includes background information in mechanics and cell biology • Explores application areas such as tissue engineering • Contains references at the end of each chapter to facilitate further study Selected Contents Basic Science Tools for Mechanobiology Research An Introductory Guide to Solid Mechanics Fluid Mechanics Molecular Analysis in Mechanobiology Literature Review of Mechanobiology: Research Findings and Theories Cardiovascular Systems Musculoskeletal Systems Other Organ Systems Frontiers of Mechanobiology Index Catalog no. 91212, March 2011, 563 pp. ISBN: 978-1-4200-9121-2, $169.95 / £109.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Biomechanics Biomechanics of the Upper Limbs
Microfluidics and Nanofluidics Handbook
Mechanics, Modeling and Musculoskeletal Injuries, Second Edition
Two-Volume Set
Andris Freivalds
Pennsylvania State University, University Park, USA
Over the past two decades, the growth in computer-related jobs has led to considerable increase in the number of work-related musculoskeletal disorders in the upper limbs. Now in its second edition, Biomechanics of the Upper Limbs: Mechanics, Modeling and Musculoskeletal Injuries is now expanded to include recent findings regarding job stressors and a variety of ergonomic solutions. This comprehensive text provides up-to-date research on the biomechanics of the upper limbs and the mechanics of neuromuscular systems. It covers risk factors for various disorders and tools used to identify their causes. • Provides numerous examples in each chapter • Features downloadable PowerPoint® slides, sample exams, and other background material on a supporting website • Includes an instructor’s manual with complete solutions • Contains end-of-chapter references to enhance further study Selected Contents Introduction to Biomechanics Structure of the Musculoskeletal System Neuromuscular Physiology and Motor Control Modeling of Muscle Mechanics Models of the Upper Limbs
Edited by
Sushanta K. Mitra University of Alberta, Edmonton, Canada
Suman Chakraborty
Indian Institute of Technology (IIT), Kharagpur, India
A comprehensive, two-volume handbook on microfluidics and nanofluidics, this text covers fundamental aspects, fabrication techniques, introductory materials on microbiology and chemistry, measurement techniques, and applications with special emphasis on the energy sector. Each chapter begins with introductory coverage to a subject and then focuses in on advanced techniques and concepts, making it valuable to students and practitioners. Figures, tables, and equations illustrate the concepts. Catalog no. K10859, September 2011, 1766 pp. ISBN: 978-1-4398-1671-4, $279.95 / £178.00 Also available as an eBook
Also available as individual volumes
Fabrication, Implementation, and Applications Selected Contents Experimental and Numerical Methods: ImageBased Photonic Techniques for Microfluidics. Recent Developments in Microparticle Image Velocimetry. Near-Surface Particle-Tracking Velocimetry. ... Catalog no. K10860, September 2011, 641 pp. ISBN: 978-1-4398-1672-1, $179.95 / £109.00 Also available as an eBook
Instrumentation
Chemistry, Physics, and Life Science Principles
Job and Worksite Analysis
Selected Contents
Hand Tools
Physics and Transport Phenomena: An Overview of Continuum Description of Fluid Flow and Transport Processes. Microscale Gas Flow Dynamics and Molecular Models for Gas Flow and Heat Transfer. Calculations of Rarefied Gas Flows in Free-Molecular and Transitional Regimes. Ideal Gas Flows through MicroChannels—Revisited. ...
Musculoskeletal Disorders and Risk Factors
The Office Environment Catalog no. 91190, February 2011, 564 pp. ISBN: 978-1-4200-9119-9, $119.95 / £76.99 Also available as an eBook
Catalog no. K10862, September 2011, 1125 pp. ISBN: 978-1-4398-1676-9, $179.95 / £109.00 Also available as an eBook
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Biomechanics Principles of Biomechanics Ronald L. Huston
University of Cincinnati, Ohio, USA
Presenting the fundamental concepts that are required for further research in this field, this volume emphasizes biodynamic modeling and human body models. Catalog no. DK494X, December 2008, 442 pp. ISBN: 978-0-8493-3494-8, $115.95 / £73.99 Also available as an eBook
Applied Biomedical Engineering Mechanics Dhanjoo N. Ghista
Wayland, Massachusetts, USA
Exploring the latest innovations, this text highlights advances in tissue, musculoskeletal, locomotive, orthopedic, occupational, ergonomic, sports, cardiovascular, cardiac, and pulmonary biomechanics. Catalog no. DK8315, July 2008, 552 pp. ISBN: 978-0-8247-5831-8, $149.95 / £96.00 Also available as an eBook
Biomechanics Principles and Applications, Second Edition
Foot and Ankle Motion Analysis Clinical Treatment and Technology Gerald F. Harris
Marquette University, Milwaukee, Wisconsin, USA
Peter A. Smith
Shriners Hospital for Children, Chicago, Illinois, USA
Richard A. Marks
Medical College of Wisconsin, Milwaukee, USA
Originating as a one-day workshop sponsored by the Shriner’s Hospitals and the National Institutes of Health, this text is a single source reference for the latest assessment technologies and their clinical applications. Catalog no. 3971, August 2007, 704 pp. ISBN: 978-0-8493-3971-4, $209.95 / £134.00 Also available as an eBook
Biomechanics and Exercise Physiology Quantitative Modeling Arthur T. Johnson University of Maryland, College Park, USA
Using numerous worked examples to demonstrate what and when to calculate, this text covers more than just the fundamentals of exercise physiology. It demonstrates the vast amount of physiological material that can be quantitatively predicted and describes how to translate this information into applications. Catalog no. DK5813, March 2007, 688 pp. ISBN: 978-1-57444-906-8, $135.95 / £87.00
Donald R. Peterson University of Connecticut, Farmington, USA
Biomechatronics in Medicine and Healthcare
Joseph D. Bronzino
Edited by
Edited by
Trinity College, Hartford, Connecticut, USA
Drawn from the third edition of the widely acclaimed Biomedical Engineering Handbook, this is a comprehensive presentation of the current principles and applications of biomechanics integrating both systems and subsystems models. Catalog no. 8534, September 2007, 352 pp. ISBN: 978-0-8493-8534-6, $104.95 / £66.99 Also available as an eBook
Raymond Tong Kaiyu
Hong Kong Polytechnic University, Hung Hom, Kowloon
This book presents experts’ insights into the emerging technologies and developments that are being or will be utilized in the medical profession to meet a variety of clinical challenges. Catalog no. N10425, August 2011, 250 pp. ISBN: 978-981-4241-61-8, $149.95 / £95.00 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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Biotransport Coming Soon!
Basic Transport Phenomena in Biomedical Engineering
Transport Phenomena in Biomedical Engineering
Third Edition
Principles and Practices
Ronald L. Fournier
Edited by
University of Toledo, USA
Exploring fundamental engineering and life science principles to uncover key concepts in biomedical engineering transport phenomena, this volume begins with a review of the basics of thermodynamics. It then examines the physical properties of body fluids and the cell membrane before moving on to topics such as properties of blood, solute transport, pharmacokinetic analysis, extracorporeal devices, tissue engineering, and bioartificial organs. Each chapter ends with problems to help clarify the material. • Provides an introductory level text for students in bioengineering, chemical engineering, mechanical engineering, and the life sciences • Presents a basic understanding and the theories of transport in biological systems and then builds on this knowledge base to show real-world applications in the development and design of artificial organs, drug delivery systems, and tissue engineering • Includes numerous examples with a discussion of the numerical methods used to solve the problems
Robert A. Peattie, Robert J. Fisher, Joseph D. Bronzino, and Donald R. Peterson This book couples the concepts of transport phenomena with chemical reaction kinetics and thermodynamics to introduce the field of reaction engineering. This is essential information needed to design and control engineering devices, particularly flow reactor systems. Similar concepts are brought forth and reinforced through applications and discussions. To further enhance the benefits obtained by the reader, the book first examines some elementary concepts. It provides a comprehensive treatment with an overview of major research topics related to transport phenomena pertaining to biomedical engineering. Catalog no. K13460, November 2012, c. 180 pp. ISBN: 978-1-4398-7462-2, $149.95 / £95.00 Also available as an eBook
Advances in Numerical Heat Transfer Volume Three
• Contains an extensive bibliography of the research literature that supports the material in the text
Edited by
• Supplies numerous illustrations, with homework problems at the end of each chapter
E.M. Sparrow
Solutions manual available with qualifying course adoption
Selected Contents Introduction. A Review of Thermodynamic Concepts. Physical Properties of the Body Fluids and the Cell Membrane. The Physical and Flow Properties of Blood. Solute Transport in Biological Systems. Pharmacokinetic Analysis. Extracorporeal Devices. Tissue Engineering. Bioartificial Organs. Index. Catalog no. K11304, August 2011, 483 pp. ISBN: 978-1-4398-2670-6, $89.95 / £44.99 Also available as an eBook
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W.J. Minkowycz
University of Illinois at Chicago, USA University of Minnesota, Minneapolis, USA
With contributions from renowned international researchers who cover both fundamentals and applications, this volume provides a definitive treatment of the numerical simulation of bioheat transfer and fluid flow. It covers novel modeling techniques and numerical simulation for solving problems in biomedical engineering. The book presents various forms of the bioheat equation appropriate for several thermal therapies. It also discusses tumor detection and treatment, shows how nanoparticles can be used to improve the efficacy of tumor treatment, and includes a case study describing the thermal ablation of an enlarged prostate. Catalog no. 95218, March 2009, 400 pp. ISBN: 978-1-4200-9521-0, $174.95 / £112.00 Also available as an eBook
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General Books in Bioengineering Introduction to Biomedical Engineering Technology
Biologically Inspired Robotics
Second Edition
Yunhui Liu
Laurence J. Street
Rosedale, British Columbia, Canada
Thoroughly revised and updated, this second edition describes current technological devices, the physiological and anatomical basis of their function, their practical applications, and their common locations in hospitals. Written by an experienced biomedical engineering technologist, the text discusses tools and test equipment, examines the integration of equipment within the hospital system, and presents an overview of various kinds of hardware related to medical equipment. Throughout, it incorporates real-life examples of the work that biomedical engineering technologists do, preparing students for situations they will encounter on the job.
Edited by The Chinese University of Hong Kong
Dong Sun
City University of Hong Kong, Kowloon
Solutions manual available with qualifying course adoption
This reference contains cutting-edge material— considerably expanded and with additional analysis—from the 2009 IEEE International Conference on Robotics and Biomimetics. The 16 chapters cover biologically inspired robot design and control, micro/nano robots for bio-systems and biomedicine, biological measurement and actuation, and applications of robotics technology to biological problems. A state-of-the-art resource for graduate students and researchers in control engineering, robotics, and biomedical engineering, this text helps readers understand the technology and principles in this emerging field. It includes a wealth of illustrations and equations.
Catalog no. K12781, October 2011, 391 pp. ISBN: 978-1-4398-6058-8, $89.95 / £56.99 Also available as an eBook
Catalog no. K12555, December 2011, 340 pp. ISBN: 978-1-4398-5488-4, $99.95 / £63.99 Also available as an eBook
Biomedical Engineering Principles Second Edition Arthur B. Ritter, Vikki Hazelwood, Antonio Valdevit, and Alfred N. Ascione Praise for the Previous Edition “[Provides] not only an in-breadth overview on current BME fields, but also an in-depth analysis of specific selected topics that are supported by appropriate mathematical models, equations, quantitative data charts and tables.” —Biomedical Engineering Online
“... an excellent resource to explain the many intricacies of biomedical engineering ...” —Richard C. Fries, PE, CRE, Baxter Healthcare, Inc., in IEEE Engineering in Medicine and Biology Magazine Solutions manual and figure slides available with qualifying course adoption
Catalog no. K10621, May 2011, 540 pp. ISBN: 978-1-4398-1232-7, $99.95 / £63.99 Also available as an eBook
Dynamics of Biological Systems Michael Small
Hong Kong Polytechnic University
With exercises and projects in each chapter, this classroom-tested text shows how to apply a variety of mathematical and computational techniques to model and analyze the temporal and spatial phenomena of biological systems. The mathematical models and computer simulations offer insight into cardiac pacemakers, artificial electrical defibrillation, pandemics, pattern formation, flocking behavior, the interaction of autonomous agents, and hierarchical and structured network topologies. MATLAB® implementations of algorithms and case studies are available on the author’s website. Solutions manual available with qualifying course adoption
Catalog no. K12463, August 2011, 284 pp. ISBN: 978-1-4398-5336-8, $79.95 / £49.99 Also available as an eBook
For more information and complete contents, visit www.crcpress.com
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General Books in Bioengineering Introduction to Molecular Biology, Genomics and Proteomics for Biomedical Engineers
Biology for Engineers Arthur T. Johnson University of Maryland, College Park, USA
Introducing the field of biology to today’s engineering students, this entry-level text minimizes unnecessary memorization of connections and classifications and emphasizes concepts, technology, and the utilization of living things. Filled with practical examples, the book discusses biological responses from the perspectives of psychology, human factors, genetics, plant and animal physiology, imaging, control systems, actuary, and medicine. Offering numerous tables of useful information, it covers the scaling of biological responses and attributes as well as different types of applications related to biological systems. Solutions manual available with qualifying course adoption
Catalog no. 77635, September 2010, 775 pp. ISBN: 978-1-4200-7763-6, $104.95 / £66.99 Also available as an eBook
Robert B. Northrop and Anne N. Connor “... a solid introduction and a foundation that the interested student might use as a basis for further study at a more advanced level.” —Books-On-Line
This introductory text is written for engineers and scientists with little background in molecular biology, genomics, and proteomics, who are working with, or planning to work with, living systems. The authors assume familiarity with basic calculus, physics, and linear algebra. They describe the very complex biochemical relations that permit life to exist, highlighting the specialized organic molecules in living organisms, and how they interact and react. Catalog no. 61194, October 2008, 480 pp. ISBN: 978-1-4200-6119-2, $107.95 / £69.99
Coming Soon!
Clinical Procedures for Medical Technology Specialists Laurence J. Street
Chilliwack General Hospital, Rosedale, British Columbia, Canada
Physics of Thermal Therapy Fundamentals and Clinical Applications Edited by
Eduardo Moros
Moffitt Cancer Center, Tampa, Florida, USA
—Ahmet Turkmen, PhD, MS, BS, University of Wisconsin, in Biomedical Instrumentation & Technology
Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of thermal therapy. An overview of the fundamentals shows how use of controlled heat in medicine and biology involves electromagnetics, acoustics, thermodynamics, heat transfer, and imaging sciences. The book discusses challenges in the use of thermal energy on living tissues and explores genetic, cellular, and physiological responses that will help in combating cancer. It also highlights recent advances, including the treatment of solid tumors using image-guided thermal therapy, microbubbles, nanoparticles, and other cutting-edge techniques.
Catalog no. 81993, October 2010, 344 pp. ISBN: 978-1-4200-8199-2, $72.95 / £45.99 Also available as an eBook
Catalog no. K12209, December 2012, c. 424 pp. ISBN: 978-1-4398-4890-6, $149.95 / £95.00 Also available as an eBook
“... describes more than 80 diagnostic and therapeutic clinical procedures from a wide variety of medical specializations. … I can recommend the book to all paramedical staff including biomedical equipment technicians and all those involved in medical technology management. ... a very good encyclopedic resource to learn about various procedures … All procedure descriptions are formatted in a similar manner and supported with the information in the introduction chapter and the appendices.”
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Forthcoming! The Biomedical Engineering Handbook Four-Volume Set, Fourth Edition Joseph D. Bronzino and Donald R. Peterson Catalog no. K11205, April 2013, c. 4500 pp. ISBN: 978-1-4398-2533-4, $309.95 / £197.00 Also available as individual volumes
Biomedical Engineering Fundamentals, Fourth Edition Catalog no. K11198, April 2013, c. 1200 pp., Soft Cover, ISBN: 978-1-4398-2518-1, $189.95 / £121.00
Medical Devices and Systems, Fourth Edition Catalog no. K11201, April 2013, c. 1200 pp., Soft Cover, ISBN: 978-1-4398-2525-9, $189.95 / £121.00
Tissue Engineering and Artificial Organs, Fourth Edition Catalog no. K11204, April 2013, c. 1200 pp., Soft Cover, ISBN: 978-1-4398-2530-3, $189.95 / £121.00
Molecular Engineering, Fourth Edition Catalog no. K11202, January 2013, c. 1200 pp. ISBN: 978-1-4398-2527-3, $189.95 / £121.00 Set and individual volumes available as eBooks
Medical Instruments and Devices, Principles and Practices Edited by
Steven Schreiner, Joseph D. Bronzino, and Donald R. Peterson Catalog no. K13272, February 2013, c. 400 pp. ISBN: 978-1-4398-7145-4, $99.95 / £63.99 Also available as an eBook
Measurement,Instrumentation, and Sensors Handbook Second Edition, Two-Volume Set Edited by
John G. Webster and Halit Eren Catalog no. K12205, May 2013, c. 2700 pp. ISBN: 978-1-4398-4883-8, $249.95 / £159.00 Also available as individual volumes
Spatial, Time, and Mechanical Measurement, Second Edition Catalog no. K12208, May 2013, c. 1250 pp. ISBN: 978-1-4398-4888-3, $149.95 / £95.00
Electromagnetic, Optical, Radiation, Chemical, and Biomedical Measurement, Second Edition Catalog no. K12210, May 2013, c. 1250 pp. ISBN: 978-1-4398-4891-3, $149.95 / £95.00 Set and individual volumes available as eBooks
Regenerative Engineering Edited by
Cato T. Laurencin and Yusuf Khan
University of Connecticut Health Center, Farmington, USA
Catalog no. K10724, April 2013, c. 400 pp. ISBN: 978-1-4398-1412-3, $99.95 / £63.99 Also available as an eBook
Fundamentals of Biomechanics Ronald L. Huston
University of Cincinnati, Ohio
Catalog no. K14776, March 2013, c. 500 pp. ISBN: 978-1-4665-1037-1, $99.95 / £63.99
For more information and complete contents, visit www.crcpress.com
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Forthcoming Biomechanics
Biomaterials
Principles and Practices
Principles and Practices
Edited by
Edited by
Donald R. Peterson and Joseph D. Bronzino
Joyce Y. Wong, Joseph D. Bronzino, and Donald R. Peterson
Catalog no. K13252, February 2013, c. 350 pp. ISBN: 978-1-4398-7098-3, $139.95 / £89.00 Also available as an eBook
Catalog no. K13339, December 2012, c. 272 pp. ISBN: 978-1-4398-7251-2, $139.95 / £89.00 Also available as an eBook
Biomimetics and Ocean Organisms
Nanomedicine
An Engineering Design Perspective
Raj Bawa, Joseph D. Bronzino, and Donald R. Peterson
Iain A. Anderson and Julian Vincent
Principles and Practices
Catalog no. K11710, February 2013, c. 400 pp. ISBN: 978-1-4398-3762-7, $169.95 / £108.00
Catalog no. K13710, February 2013, 300 pp. ISBN: 978-1-4398-7923-8, $139.95 / £89.00 Also available as an eBook
OMICS
RNA Nanotechnology and Therapeutics
Applications in Biomedical, Agricultural, and Environmental Sciences Edited by
Debmalya Barh, Vasudeo Zambare, and Vasco Azevedo
Peixuan Guo
University of Cincinnati, Ohio, USA
Catalog no. K14577, June 2013, c. 400 pp. ISBN: 978-1-4665-0566-7, $179.95 / £114.00 Also available as an eBook
Catalog no. K15973, January 2013, c. 350 pp. ISBN: 978-1-4665-6281-3, $169.95 / £108.00 Also available as an eBook
MEMS Packaging and Technology
Nanotechnology and Human Health
Edited by
Ineke Malsch
Vikas Choudhary and Krzysztof Iniewski Catalog no. K15054, February 2013, c. 400 pp. ISBN: 978-1-4665-1581-9, $149.95 / £95.00 Also available as an eBook
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Malsch Techno Valuation, Utrecht, Netherlands
Catalog no. 8144, March 2013, c. 300 pp. ISBN: 978-0-8493-8144-7, $139.95 / £89.00 Also available as an eBook
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From the Rehabilitation Science in Practice Series
CRC Press/Taylor & Francis is pleased to announce the launch of an innovative series— Rehabilitation Science in Practice. This series will publish books and monographs based on cutting-edge research and development within all viable areas of the rehabilitation sciences. The publisher and the series editors are committed to providing high quality books to a global audience of practitioners, researchers, scientists, and clinicians. As we are fully aware of the rapidly evolving nature of the subject and its long-lasting impact on the quality of human life, the team of editors is committed to making this series the most comprehensive and accurate resource in the field of rehabilitation science.
CALL FOR AUTHORS The publisher and series editors are actively seeking timely proposals from authors for technical books, handbooks, and references on topics including: • • • • • • •
Rehabilitation engineering Pediatric rehabilitation engineering Telemedicine Telerehabilitation Quality of life technology Multiple sclerosis rehabilitation Rehabilitation robotics
• • • • • • •
Assistive technologies Healthcare engineering Mobility enhancement Manipulation ability Cognitive function Neuro trauma Remote patient monitoring
Contact Michael Slaughter Executive Editor CRC Press/Taylor & Francis Group, LLC Phone: 415.897.1238 • Fax: 415.320.2254 • E-mail: michael.slaughter@taylorandfrancis.com Marcia J. Scherer Institute for Matching Person & Technology Phone/Fax: 585.671.3461 • E-mail: IMPT97@aol.com Dave Muller Chief Executive, Suffolk New College E-mail: davemuller@suffolk.ac.uk
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