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Table of Contents Biomedical Engineering Biochemistry....................................................................................................................................................................3 Biomaterials & Medical Devices........................................................................................................................................7 Biomedical Engineering..................................................................................................................................................11
Biotechnology................................................................................................................................................................34 Methods & Instrumentation...........................................................................................................................................39 Nanobiotechnology.......................................................................................................................................................42 Biomedical Science Cell Biology....................................................................................................................................................................49 Immunology..................................................................................................................................................................50 Lab Animals....................................................................................................................................................................50 Microbiology..................................................................................................................................................................53 Molecular Biology..........................................................................................................................................................54 Neuroscience.................................................................................................................................................................54 Toxicology......................................................................................................................................................................59 Pharmaceutical Science Biopharmaceuticals........................................................................................................................................................61 Bioprocessing.................................................................................................................................................................63 Clinical Trials..................................................................................................................................................................63 Drug Discovery & Development.....................................................................................................................................65 Management.................................................................................................................................................................67 Pharmaceutical Science..................................................................................................................................................68 Pharmacology................................................................................................................................................................68 Mathematics & Statistics for Biomedicine Bioinformatics................................................................................................................................................................70 Biostatistics & Epidemiology...........................................................................................................................................71 Computational Biology...................................................................................................................................................75 Mathematics for Biology & Medicine..............................................................................................................................77 Statistics for Biological Science.......................................................................................................................................79 General References..............................................................................................................................................................88 Title Index.............................................................................................................................................................................91 Author Index.........................................................................................................................................................................96 Sales Agents........................................................................................................................................................................103
Biomedical Sciences
Biomedical Imaging........................................................................................................................................................26
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Taylor & Francis Group
Advanced Practical Organic Chemistry
Applications of Supramolecular Chemistry Edited by
Hans-Jörg Schneider
Third Edition
Universitat des Saarlandes, Saarbrucken, Germany
John Leonard, Barry Lygo, and Garry Procter
Covering the most important supramolecular technologies within a single volume, this book provides a comprehensive introduction for both newcomers to the field and for specialists who are looking for new applications. Internationally recognized specialists in the different fields describe in detail the most promising but already established techniques, including biotechnology, decontamination, environmental control, biomedical analyses/ monitoring, supramolecular electronics, and intelligent materials. The text offers a complete overview of important applications in supramolecular chemistry, which hold particular promise for future developments.
With an emphasis on the most up-to-date techniques commonly used in organic synthesis, this third edition of a bestseller draws on the extensive experience of the authors and their association with some of the world’s leading laboratories of synthetic organic chemistry. Written mainly for graduate and advanced undergraduate students as well as industrial organic chemists, this book provides sufficient guidance to allow the researcher to carry out reactions under conditions that offer the highest chance of success. It offers fully updated information and re-drawn figures to illustrate the information at the highest possible standard. Figure slides are available upon qualifying course adoption. Print ISBN: 978-1-4398-6097-7 eBook ISBN: 978-1-4398-6098-4 January 2013, 6-1/8 x 9-1/4, 356 pp., Soft Cover Suggested Price: $69.95 / £44.99
Print ISBN: 978-1-4398-4014-6 eBook ISBN: 978-1-4665-5832-8 March 2012, 6-1/8 x 9-1/4, 453 pp. Suggested Price: $104.95 / £66.99
Amino Acid Chelation in Human and Animal Nutrition
Carbohydrate Chemistry
H. DeWayne Ashmead
Edited by
Albion Laboratories, Clearfield, Utah, USA
Gijsbert van der Marel
An examination of the increased bioavailability of amino acid chelates, this book assembles chemical, clinical, and nutritional studies explaining how the body responds to amino acid chelates. It presents analytical procedures for producing amino acid chelates that are used in research relating to mineral bioavailability. The chapters cover fundamentals of mineral nutrition, the chemistry of chelation, the history of nutritional chelates, absorption pathways, tissue metabolism and metabolic responses, nutrient uptake, and toxicity of amino acid chelates.
Leiden University, The Netherlands
Print ISBN: 978-1-4398-9767-6 eBook ISBN: 978-1-4398-9768-3 February 2012, 6-1/8 x 9-1/4, 269 pp. Suggested Price: $135.95 / £86.00
Amino Acids
Proven Synthetic Methods, Volume 2
Jeroen Codee Leiden University, The Netherlands Series: Carbohydrate Chemistry
This second volume in the series is a compilation of reliable protocols for the preparation of intermediates for carbohydrate synthesis or other substances and methods performed at the bench, which can be expected to be useful in the glycosciences. Written for graduate students and researchers in carbohydrate chemistry, biochemistry, medical chemistry, and glycobiology, this book explores carbohydrate chemistry from both academic and industrial points of views, offering contributions from world-renowned experts. It includes figures to aid in reader comprehension. Print ISBN: 978-1-4398-7594-0 January 2014, 6-1/8 x 9-1/4, 330 pp. Suggested Price: $149.95 / £95.00
Biochemistry and Nutrition
Chemical Genomics and Proteomics
Guoyao Wu
Second Edition
Texas A & M University, College Station,Texas, USA
This up-to-date book presents basic concepts and recent advances in amino acid biochemistry and nutrition, providing comprehensive coverage of developments over the past half-century. It includes information on dietary protein digestion, quality, and requirements, while addressing absorption, transport, synthesis, degradation of amino acids, and intracellular protein turnover in animals. The text integrates cell-, tissue-, and species-specific metabolic pathways of amino acids with health and disease in various organisms. The author also presents a critical analysis of amino acid supplementation to humans and other animals. Print ISBN: 978-1-4398-6189-9 eBook ISBN: 978-1-4398-6190-5 April 2013, 6-1/8 x 9-1/4, 503 pp. Suggested Price: $99.95 / £63.99
Biochemistry
Textbook
Edited by
Ferenc Darvas, András Guttman, and György Dormán Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics and lipidomics. This second edition has been updated to uniquely reflect this interdisciplinary feature as well as the remarkable developments that have occurred. The new edition also covers innovative applications from cell biology to drug discovery to, more recently, clinical diagnostics and medical practice. Print ISBN: 978-1-4398-3052-9 eBook ISBN: 978-1-4398-3059-8 January 2013, 6-1/8 x 9-1/4, 243 pp. Suggested Price: $159.95 / £99.00
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Chemical Reagents for Protein Modification Fourth Edition
CRC Handbook of Organic Photochemistry and Photobiology
Roger L. Lundblad
Third Edition, Two-Volume Set
Lundblad Biotechnology, Chapel Hill, North Carolina, USA
This volume is a catalog of the many chemicals known to affect the covalent modification of proteins. This includes not only chemicals used for the specific modification of amino acids in proteins, but also chemicals in the environment that modify proteins. The work builds on the previous editions but includes a change in format. Information is presented based on the chemical nature of the modifying material and on the amino acid residue modified. Much of the information is in tabular form to enable rapid location of cited material.
Biochemistry
Print ISBN: 978-1-4665-7190-7 May 2014, 7 x 10, 704 pp. Suggested Price: $159.95 / £99.00
Axel Griesbeck University of Cologne, Germany
Michael Oelgemöller James Cook University, Townsville, Queensland, Australia
Francesco Ghetti CNR Istituto Biofisica, Pisa, Italy
With a new editorship and expanded contents, the third edition of this bestselling handbook continues to provide an authoritative and unique resource for those working and studying in the areas of photochemistry and photobiology. Leading experts offer enlightening contributions on traditional topics, current trends, and future directions. New and updated topics in this edition include industrial and microphotochemistry, photoimmunology, artificial photosynthetic systems, phototoxicity of drugs, and much more. Print ISBN: 978-1-4398-9933-5 eBook ISBN: 978-1-4665-6125-0 March 2012, 7 x 10, 1694 pp. Suggested Price: $503.00 / £320.00
Chemistry of Heterocyclic Compounds Rakesh Kumar Parashar University of Delhi, India
This book addresses the structure, synthesis, and reactivity of heterocyclic compounds. It covers nomenclature, conformational aspects, aromatic stabilization, and biological activity of heterocyclic compounds. The book also contains discussions of biochemical processes involving destruction of heterocyclic rings. It provides problem sets that help readers to understand and apply the principles of heterocyclic reactivity and synthesis. The inclusion of more advanced material and references makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds, particularly in the pharmaceutical and agrochemical industries.
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Every Molecule Tells a Story Simon Anthony Cotton University of Birmingham, School of Chemistry, UK
Written by a seasoned teacher, speaker, and writer in the field of chemistry, this text provides guidance on chemicals that make life possible and enrich the senses, as well as those that endanger it. It combines the science and history of many molecules and deals with the chemistry of each substance in an interesting and easily understandable manner. Topics covered include substances found in air and water, food, hydrocarbons, acids and alkalis, natural killers, unnatural killers, destructive molecules, pleasure molecules, manmade healers, and more.
Print ISBN: 978-1-4665-1713-4 June 2013, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $89.95 / £57.99
Print ISBN: 978-1-4398-0773-6 eBook ISBN: 978-1-4398-0774-3 November 2011, 6-1/8 x 9-1/4, 280 pp. Suggested Price: $62.95 / £40.99
Computational Chemogenomics
Fluctuation Theory of Solutions
Edited by
Applications in Chemistry, Chemical Engineering, and Biophysics
Edgar Jacoby Novartis Pharma AG, Basel, Switzerland
This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity analysis. Both ligand-based and structure-based in silico approaches, as reviewed in this book, play important roles for all these applications. Computational chemogenomics is expected to increase the quality and productivity of drug discovery and lead to the discovery of new medicines. Print ISBN: 978-981-4411-39-4 November 2013, 6 x 9, 264 pp. Suggested Price: $149.95 / £95.00
Edited by
Paul E. Smith, Enrico Matteoli, and John P. O’ Connell Fluctuation Solution Theory (FST) is an exact theory that can be applied to any stable solution regardless of the number of components and their concentrations, and the types of molecules and their sizes. It is the most complete and accurate approach available for theoretically understanding solution mixture thermodynamic properties. This book outlines the general concepts and theoretical basis of FST and provides a range of applications described by experts in chemistry, chemical engineering, and biophysics. The text elucidates this rigorous and useful approach for understanding a wide array of solution properties. Print ISBN: 978-1-4398-9922-9 eBook ISBN: 978-1-4398-9923-6 February 2013, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $129.95 / £82.00
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Fundamental QSARs for Metal Ions
Hansen Solubility Parameters
John D. Walker, Michael C. Newman, and Monica Enache
Charles M. Hansen
Focusing on the field of metal ion bioactivity in Quantitative Structure Activity Relationships (QSAR), this book concentrates on the basic and essential applications of QSAR methods in metal ions for readers familiar with the field and statistics. It delineates the theoretical basis and provides a concrete introduction to studying the biological activity and toxicity of metal ions as they impact health and the environment. The book describes the applications of QSARs in characterizing the biological activity and toxicity of metal ions and provides parameters for the correlation of structure with inorganic biological activity.
In this new edition, Charles M. Hansen invites five renowned experts to share their innovative work on novel topics such as using statistical thermodynamics to confirm existing HSPs, reconciling HSP with other thermodynamic theories, predicting the behavior of carbon dioxide, environmental stress cracking, absorption and diffusion in polymers, and other insight on future applications in biological materials, controlled release, nanotechnology, and self-assembly. The book highlights recent findings on interactions with DNA, and other novel applications of HSPs, such as ozone-safe solvents, protective clothing, drug delivery systems, and petroleum applications.
Print ISBN: 978-1-4200-8433-7 eBook ISBN: 978-1-4200-8434-4 December 2012, 6-1/8 x 9-1/4, 302 pp. Suggested Price: $139.95 / £89.00
Print ISBN: 978-0-8493-7248-3 eBook ISBN: 978-1-4200-0683-4 June 2007, 7 x 10, 544 pp. Suggested Price: $210.00 / £133.00
Handbook of Lipid Bilayers
Introduction to Lipidomics
Second Edition
From Bacteria to Man
Derek Marsh
Claude Leray
Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany
This handbook provides the only one-stop resource for primary physicochemical data relating to phospholipid bilayers. Coverage includes both dynamic and structural properties of phospholipid bilayers, along with basic thermodynamic data. With more than twice as much data, this second edition contains new sections on phase diagrams with cholesterol, hydration isotherms, spontaneous curvature, and cubic phases. It also presents expanded information on glycolipids and includes more detailed introductory sections that explain important concepts and provide a broader framework for understanding the data.
A User’s Handbook, Second Edition
The first comprehensive book on lipidomics, this longawaited work inventories the huge variety of lipid molecules present in all aspects of life, detailing structures from animal, plant, and bacterial cells, marine ecosystems, and little-known structures from bibliographic data. A true text rather than just a catalog, it is highly informative and educational while simultaneously being anecdotal and interesting to read. Print ISBN: 978-1-4665-5146-6 eBook ISBN: 978-1-4665-5147-3 September 2012, 6-1/8 x 9-1/4, 339 pp., Soft Cover Suggested Price: $104.95 / £66.99
Print ISBN: 978-1-4200-8832-8 eBook ISBN: 978-1-4200-8833-5 February 2013, 8-1/2 x 11, 1174 pp. Suggested Price: $249.95 / £159.00
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Handbook of Vitamins
Introduction to Proteins
Fifth Edition
Structure, Function, and Motion
Edited by
Amit Kessel
Janos Zempleni, John W. Suttie, Jesse F. Gregory, III, and Patrick J. Stover
Es-is Technologies Ltd., Givatayim, Israel
Within the last few years, knowledge about vitamins has increased dramatically. This new edition of a bestseller presents comprehensive summaries that analyze the chemical, physiological, and nutritional relationships, as well as highlight newly identified functions, for all recognized vitamins. Keeping the tradition of the previous volumes, the Handbook of Vitamins, Fifth Edition provides an updated, contemporary perspective on vitamins in human nutrition. It contains substantial revisions throughout and a new chapter on vitamin– genome interactions. Print ISBN: 978-1-4665-1556-7 eBook ISBN: 978-1-4665-1557-4 July 2013, 7 x 10, 605 pp. Suggested Price: $149.95 / £95.00
Biochemistry
Charles M. Hansen Consulting, Hoersholm, Denmark
Nir Ben-Tal Tel Aviv University, Israel Series: Chapman & Hall/CRC Mathematical & Computational Biology
With more than 350 color images throughout, this text presents a unified, in-depth treatment of the relationship between the structure, dynamics, and function of proteins. Taking a structural–biophysical approach, the authors discuss the molecular interactions and thermodynamic changes that transpire in these highly complex molecules. They use numerous proteins as examples to illustrate the topics and principles and to show how proteins can be analyzed in multiple ways. The text refers to many everyday applications of proteins and enzymes in medical disorders, drugs, toxins, chemical warfare, and animal behavior. Downloadable questions for each chapter are available at CRC Press Online. Print ISBN: 978-1-4398-1071-2 eBook ISBN: 978-1-4398-1072-9 December 2010, 7 x 10, 654 pp. Suggested Price: $91.95 / £58.99
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Liposomes, Lipid Bilayers, and Model Membranes
Textbook
From Basic Research to Application
An Acid—Base Approach
Edited by
Michael B. Smith
Georg Pabst, Norbert Kucerka, Mu-Ping Nieh, and John Katsaras With contributions from leading researchers in their fields, this book provides a comprehensive collection of state-of-the-art lipid/model membrane research and industrial/technological applications all in one volume. It is divided into two sections. The first section covers recent lipid/model membrane research, while the second provides examples of how lipid systems have been successfully used in the pharmaceutical, textile, and food industries.
Biochemistry
Print ISBN: 978-1-4665-0709-8 March 2014, 7 x 10, 479 pp. Suggested Price: $149.95 / £95.00
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Organic Chemistry University of Connecticut, Storrs, USA
Most reactions in organic chemistry can be explained by variations of fundamental acid–base concepts. This volume provides a framework for understanding the subject that goes beyond mere memorization. Using several techniques to develop a relational understanding, this text helps students fully grasp the concepts at the root of organic chemistry. Chapters contain checklists of what students need to know before they begin to study a topic and concepts to be fully understood before moving to the next subject area, homework problems directly tied to each concept at the end of each chapter, embedded problems with answers throughout the material, and experimental details and mechanisms for key reactions. Print ISBN: 978-1-4200-7920-3 eBook ISBN: 978-1-4398-9462-0 October 2010, 7 x 10, 1592 pp. Suggested Price: $159.95 / £102.00
Mitochondrial Signaling in Health and Disease
PCR Technology
Edited by
Edited by
Sten Orrenius, Lester Packer, and Enrique Cadenas
Tania Nolan
Series: Oxidative Stress and Disease
Sigma Life Science Custom Products, Haverhill, UK
Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. This volume examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis. Topics include electron transport and energy production, mitochondrial biogenesis and dynamics, mitochondrial signaling, and apoptosis and autophagy. The book also explores pharmacology signaling and epigenetic signaling, with discussions on mitochondrial methylation and acetylation reactions. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction. Print ISBN: 978-1-4398-8002-9 eBook ISBN: 978-1-4398-8003-6 June 2012, 6-1/8 x 9-1/4, 528 pp. Suggested Price: $159.95 / £100.00
Current Innovations, Third Edition
Stephen A. Bustin Anglia Ruskin University, Cambridge, UK
A huge amount of innovation surrounds PCR as a molecular technique, as researchers continually think of new ways to tweak, adapt, and re-formulate concepts and applications. This volume provides a critical reference point for anyone wishing to use this technology. Topics include the purification and handling of PCR templates, the effect of the manufacture and purification of the oligonucleotide on PCR behavior, optimum buffer composition, probe options, and the design and optimization of qPCR assays. The book also explores the development and refinement of instrumentation and effective controls to protect against uncertainties due to reaction variability. Print ISBN: 978-1-4398-4805-0 eBook ISBN: 978-1-4398-4813-5 June 2013, 7 x 10, 457 pp. Suggested Price: $159.95 / £99.00
Textbook
Textbook
Organic Chemistry A Mechanistic Approach
Quantitative Understanding of Biosystems
Penny Chaloner
An Introduction to Biophysics
Imperial College, London, UK
This textbook classifies organic chemistry according to mechanism rather than classification of functional groups, with the intention of having students understand by means of problem solving. The emphasis is on the development of skills through a student-centered pedagogical approach. The inclusion of chromatography, spectroscopy, and spectrometry early in the book is an important concept. The book contains the customary chapters on biomolecules, but also presents chapters on industrially important processes and their economics, and environmental chemistry, areas in which every 21st-century-educated scientist should have familiarity. Print ISBN: 978-1-4822-0690-6 June 2014, 8-1/2 x 11, 1720 pp. Suggested Price: $129.95 / £82.00
Thomas M. Nordlund University of Alabama at Birmingham, USA
This color text clearly describes the biological physics of macromolecules, subcellular structures, and whole cells, including interactions with light. It provides a hands-on understanding of the movement of microorganisms, reviews the necessary mathematics, discusses quantum mechanics in biosystems, and describes the transition from discreet random walks to continuum diffusive motion. The text also contains standard exercises, advanced problems, and miniprojects. An accompanying CD-ROM includes “active” versions of Excel graphs and diagrams from the text, along with links to mathematical and biological/biochemical source data. Print ISBN: 978-1-4200-8972-1 eBook ISBN: 978-1-4200-8973-8 March 2011, 8-1/2 x 11, 583 pp. Suggested Price: $98.95 / £62.99
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Structural Glycobiology
Biomaterials
Edited by
Principles and Practices
Monash Institute of Pharmaceutical Sciences, Melbourne, Australia
Paul A. Ramsland Centre for Immunology, Burnet Institute, Melbourne, Australia
Structural glycobiology is a rapidly growing field of research that examines the structural and functional roles of carbohydrates. This book investigates how research findings have revealed key structural and associated biological information on carbohydrates and glycolipids. The first part presents well-established experimental approaches for the structural determination of carbohydrate–protein complexes and large glycoprotein assemblies. The second section focuses on theoretical and modeling-based approaches. The book then covers alternative and emerging techniques for yielding structural information on carbohydrates from complex biological samples. The final part discusses carbohydrates in medicine. Print ISBN: 978-1-4398-5460-0 eBook ISBN: 978-1-4398-5412-9 September 2012, 6-1/8 x 9-1/4, 347 pp. Suggested Price: $125.95 / £81.00
Edited by
Joyce Y. Wong, Joseph D. Bronzino, and Donald R. Peterson Most current applications of biomaterials involve structural functions, even in those organs and systems which are not primarily structural in their nature, or very simple chemical or electrical functions. Complex chemical functions such as those of the liver and complex electrical or electrochemical functions such as those of the brain and sense organs cannot be carried out by biomaterials at this time. With these basic concepts in mind, this book focuses on biomaterials consisting of different materials such as metals, ceramics, polymers, and composites. It highlights the impact of recent advances in the area of nanoand microtechnology on biomaterial design.
Biochemistry / Biomaterials & Medical Devices
Elizabeth Yuriev
Print ISBN: 978-1-4398-7251-2 eBook ISBN: 978-1-4398-7419-6 December 2012, 7 x 10, 281 pp. Suggested Price: $146.95 / £93.00
Biomaterials and Stem Cells in Regenerative Medicine
Textbook
Textbook of Organic Chemistry C. N. Pillai Indian Institute of Technology, Madras, India
Textbook of Organic Chemistry employs a deductive approach and reduces the need to learn by rote. Each chapter has been developed in a logical and interesting manner that facilitates easy reading and understanding. This approach has been developed and perfected by the author over the course of his tenure as a teacher of organic chemistry. Each chapter provides exercises that test the understanding of the student while strengthening the concepts discussed in the text. “Challenging Questions” are given for those students who want to delve deeper into the subject. Topics of current interest are suggested for preparing project reports. Print ISBN: 978-1-4665-5144-2 May 2012, 6 x 9, 640 pp. Suggested Price: $104.95 / £66.99
Edited by
Murugan Ramalingam, Seeram Ramakrishna, and Serena Best University of Cambridge, UK
This book brings together current knowledge on biomaterials and stem cells in the context of tissue engineering and regenerative medicine. It explores key scientific and clinical aspects, including the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications. Coverage ranges from fundamental principles to advances at the macro, micro, nano, and molecular scales. The book bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for multidisciplinary biomedical research. Print ISBN: 978-1-4398-7925-2 eBook ISBN: 978-1-4398-7926-9 July 2012, 6-1/8 x 9-1/4, 564 pp. Suggested Price: $159.95 / £100.00
Bacterial NanoCellulose A Sophisticated Multifunctional Material
Biomaterials for Stem Cell Therapy State of Art and Vision for the Future
Edited by
Edited by
Miguel Gama, Paul Gatenholm, and Dieter Klemm
Loredana De Bartolo
Series: Perspectives in Nanotechnology
Institute on Membrane Technology, Rende, Italy
The first book dedicated to the potential applications and unique properties of bacterial cellulose (BC), this seminal work covers the basic science, technology, and economic impact of this bulk chemical as well as the companies and patents that are driving the field. It reviews the biosynthesis and properties of BC, including genetics and characterization; discusses the advancing technology as it relates to product development, bioreactors, and production; and analyzes the economic impact of BC on a diverse range of industry applications, including materials and biomaterials, biological and polymer sciences, and electromechanical engineering. Print ISBN: 978-1-4398-6991-8 eBook ISBN: 978-1-4398-6992-5 November 2012, 6-1/8 x 9-1/4, 304 pp. Suggested Price: $135.95 / £86.00
Augustinus Bader Center for Biotechnology and Biomedicine (BBZ), Leipzig, Germany
This book provides state-of-the-art developments with a specific focus on the interaction of stem cells with biomaterials for constructing and regenerating tissues and organs integrating strategies from basic biology, to materials for remodeling, to production processes. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to: nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair, and cardiovascular therapy. All developments in the field reflecting the design and construction of the human body and its principal anatomy are discussed from a materials point of view. Print ISBN: 978-1-4665-7639-1 eBook ISBN: 978-1-4665-7640-7 January 2013, 6-1/8 x 9-1/4, 662 pp. Suggested Price: $199.95 / £127.00
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7
Biomaterials Science
Connective Tissue
An Integrated Clinical and Engineering Approach
Histophysiology, Biochemistry, Molecular Biology
Edited by
Nikolay Petrovich Omelyanenko, Leonid Ilyich Slutsky, and Sergey Pavlovich Mironov
Yitzhak Rosen Superior NanoBioSystems, Silver Spring, Maryland, USA
Noel Elman Cambridge, Massachusetts, USA
Biomaterials & Medical Devices
This book approaches biomaterials science not just from materials science and engineering perspectives, but also from the clinical side. It engages biomaterials engineers and physicians in a much-needed discussion that integrates both fields at many levels, helping them increase the rate of successful deployment of biomaterials, lower the side effects of such a deployment, and accumulate knowledge for improving current methodologies and meeting future challenges. Leading contributors address topics such as hemocompatibility, carcinogenesis, infections, and cellular mechanisms as well as signal transduction, clinical trials, MEMS, nanotechnology, FDA regulations, and ethical issues. Print ISBN: 978-1-4398-0404-9 eBook ISBN: 978-1-4398-0405-6 June 2012, 6-1/8 x 9-1/4, 310 pp. Suggested Price: $159.95 / £100.00
Bionanomaterials for Dental Applications Edited by
Mieczyslaw Jurczyk Poznan University of Technology, Poland
This book describes new biomaterials based on nanostructural chemically bonded bioceramics. They are widely used as general construction materials, but have also found new applications as biomaterials. These biomaterials are produced in situ and in vivo mainly using hydration reactions, which are reactions between phosphates, silicates, or aluminates and water. The text treats general and specific properties of these materials in detail and also describes the potential application area for these new materials.
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Print ISBN: 978-981-4303-83-5 eBook ISBN: 978-981-4303-84-2 October 2012, 6 x 9, 428 pp. Suggested Price: $149.95 / £95.00
This book brings together crucial knowledge of mammalian connective tissue (including human) and its components, both cellular and noncellular, in one authoritative reference. The breadth and depth of information has fundamental scientific significance as well as applied relevance in clinical medicine. The first half of the book covers the structure, classification, biochemical aspects, histogenesis, and cellular elements of connective tissue. The second half of the book reviews current data on the biochemistry and molecular biology of skeletal connective tissue, including bone and cartilage metabolism and regulation. Print ISBN: 978-1-4822-0358-5 December 2013, 8-1/2 x 11, 638 pp. Suggested Price: $169.95 / £108.00
Corrosion of Ceramic Materials Third Edition Ronald A. McCauley Rutgers, The State University of New Jersey, Piscataway, USA Series: Corrosion Technology
Filled with practical features and new information, this expanded and completely reorganized third edition helps readers address corrosion problems and create the most corrosion-resistant systems possible. Reflecting the many changes in the field since the publication of the second edition, the book includes new chapters on corrosion by biological sources as well as corrosion of architectural materials. This edition also contains more questions and examples, additional material on thermal and environmental barrier coatings, an expanded chapter on composites, and new literature sources. Print ISBN: 978-1-4398-2022-3 eBook ISBN: 978-1-4398-2023-0 January 2013, 6-1/8 x 9-1/4, 462 pp. Suggested Price: $159.95 / £99.00
Biosensors and Environmental Health
Engineering of Polysaccharide Materials
Edited by
by Phosphorylase-Catalyzed Enzymatic Chain-Elongation
Victor R. Preedy King’s College Hospital, London, UK
Vinood Patel University of Westminster, London, UK
This book provides key facts that can be applied to other areas of health and disease. It covers personal toxicity testing, soil and risk assessment, pesticide, insecticides, parasites, nitrate, endocrine disruptors, heavy metals, food contamination, whole cell bioreporters, bacterial biosensors, antibody-based biosensors, enzymatic aspects, amperometric and electrochemical aspects, quorum sensing, DNAbiosensors, cantilever biosensors, bioluminescence, and other methods and applications. The contributors are leading authorities and the book is essential reading for environmental scientists, toxicologists, medical doctors, health care professionals, pathologists, biologists, biochemists, chemists, physicists, and general practitioners as well as those interested in disease and sciences in general. Print ISBN: 978-1-57808-735-8 eBook ISBN: 978-1-4665-6566-1 August 2012, 6-1/8 x 9-1/4, 350 pp. Suggested Price: $125.95 / £81.00
Jun-ichi Kadokawa and Yoshiro Kaneko Kagoshima University, Japan
Polysaccharides and their related compounds are attracting attention due to their potential as new functional materials in many research fields such as medicine, pharmaceutics, foods, and cosmetics. Therefore, precision synthesis of new polysaccharides with well-defined structure is increasingly important. For this purpose, enzymatic method is a very powerful tool because the reaction proceeds in a manner that is highly stereo- and region-controlled. This book focuses on advances in the practical synthesis of polysaccharides by phosphorylase-catalyzed chainelongation from the perspective of polysaccharide engineering. Print ISBN: 978-981-4364-45-4 eBook ISBN: 978-981-4364-46-1 April 2013, 6 x 9, 142 pp. Suggested Price: $129.95 / £82.00
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Handbook of Harnessing Biomaterials in Nanomedicine
Textbook
Preparation, Toxicity, and Applications
Second Edition
Edited by
Edited by
Dan Peer
Jeffrey O. Hollinger
An Introduction to Biomaterials
Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers, lipids, and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nano-proteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; the use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book covers theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.
Series: Biomedical Engineering
The second edition of this popular text includes nine new chapters that provide a comprehensive and up-to-date framework for biomaterials education. A new chapter on the biology of wound healing sets the stage for the basic requirements of standardized biomaterials testing and explains the reactions between biomaterials and the living systems into which they are implanted. The book explains in vitro and in vivo testing paradigms and provides numerous examples in the chapters on experimental design, laboratory assays, and animal models. Emphasizing the importance of the regulatory process, it describes how innovation in the biomaterials process relates to patentability and inventorship.
Biomaterials & Medical Devices
Tel Aviv University, Israel
Print ISBN: 978-1-4398-1256-3 eBook ISBN: 978-1-4665-0628-2 November 2011, 7 x 10, 644 pp. Suggested Price: $125.95 / £51.99
Print ISBN: 978-981-4316-46-0 eBook ISBN: 978-981-4364-27-0 January 2012, 6 x 9, 424 pp. Suggested Price: $149.95 / £95.00
ISO 13485 Handbook of Oral Biomaterials Edited by
Jukka Pekka Matinlinna University of Hong Kong, Sai Ying Pun, China
The book introduces the latest advances in dental materials and biomaterials science. It contains a comprehensive introduction and covers ceramic, metallic, and polymeric oral biomaterials. The contributing authors are from all over the world and are distinguished in their disciplines. A solid primer for dental students, the book is also highly recommended for students of engineering and basic science who want to gain insight into contemporary biomaterials science. For medical practitioners, the book offers an invaluable opportunity to learn about the latest steps in dental biomaterials. Print ISBN: 978-981-4463-12-6 March 2014, 6 x 9, 600 pp. Suggested Price: $249.95 / £159.00
A Complete Guide to Quality Management in the Medical Device Industry Itay Abuhav Hinterforst, Switzerland
The United States and European Union now require the ISO 13485 standard certification for medical device manufacturers. Written by an experienced industry professional, this practical book provides a complete guide to the ISO 13485 standard certification for medical device manufacturing in terms of quality control. It covers all the requirements of ISO 13485 and offers a step-by-step comparison between ISO 13485 and ISO 9001, enabling a sound understanding of these new procedures. Print ISBN: 978-1-4398-6611-5 eBook ISBN: 978-1-4398-6612-2 October 2011, 6-1/8 x 9-1/4, 374 pp. Suggested Price: $146.95 / £93.00
9 Hydroxyapatite Coatings for Biomedical Applications
Marine Biomaterials
Edited by
Characterization, Isolation and Applications
Sam Zhang
Edited by
Nanyang Technological University, Singapore Series: Advances in Materials Science and Engineering
Se-Kwon Kim Pukyong National University, Busan, South Korea
With a bonelike structure that promotes osseointegration, hydroxyapatite (HA) coating can be applied to otherwise bioinactive implants to make their surfaces bioactive, thus achieving faster healing and recovery. This book explores developments in the processing, property characterization, and applications of hydroxyapatite, providing a timely resource for active researchers and newcomers to the field. HA experts from the United States, Japan, Singapore, and China present valuable insights on topics ranging from deposition processes to applications in orthopedic and dental implants and drug delivery.
Bringing together a wide range of research in this important area, this book includes the latest developments and applications of marine-derived biomaterials, from preliminary research to clinical trials. Essential reading for the novice and expert alike, it details the isolation and characterization of biomaterials and their biological activities, including antiviral, anti-allergic, and anticoagulant effects. The book also discusses the viability of low-cost marine biomaterials, biomedical applications such as tissue engineering and drug delivery, and commercialization of marine-derived products.
Print ISBN: 978-1-4398-8693-9 eBook ISBN: 978-1-4398-8694-6 May 2013, 6-1/8 x 9-1/4, 469 pp. Suggested Price: $219.95 / £140.00
Print ISBN: 978-1-4665-0564-3 eBook ISBN: 978-1-4665-0565-0 April 2013, 7 x 10, 840 pp. Suggested Price: $189.95 / £121.00
For more information and a complete list of titles, visit us at www.crcpress.com
The Medical Device R&D Handbook
Optical Techniques in Regenerative Medicine
Second Edition
Edited by
Edited by
Theodore R. Kucklick TRKD Medical Devices, Los Gatos, California, USA
Biomaterials & Medical Devices
Written for medical device designers, biomedical engineering students, physician entrepreneurs, and medical device entrepreneurs, this reference explains the basics on how to prototype and develop a medical device. It discusses the fundamentals of plastics, adhesives, medical needles, and rapid prototyping as well as tips and tools to save time and money. This updated and expanded second edition includes practical advice, information on intellectual property management, and insightful interviews from key opinion leaders and pioneers in the field. Extensive references at the end of each chapter enhance additional study. Print ISBN: 978-1-4398-1189-4 eBook ISBN: 978-1-4398-1195-5 December 2012, 6-1/8 x 9-1/4, 510 pp. Suggested Price: $179.95 / £113.00
Nanobiomaterials Development and Applications Edited by
Dong Kee Yi Gachon University, Gyeonggi-do, Republic of Korea
Georgia C. Papaefthymiou Villanova University, Pennsylvania, USA Series: Advances in Materials Science and Engineering
10
Nanobiotechnology serves as a bridge between nano and bio, with nanoscale materials providing the building blocks for the construction of the “bridge.” This book gives you a broad, interdisciplinary view of advances and applications in bionanomaterials. International contributors at the forefront of research in their disciplines explore a diverse set of topics. Coverage includes biomimetic synthesis, bioimaging and cancer diagnosis, virus-enabled manufacturing of functional nanomaterials, tumor targeting, cytotoxicity, and more. The book demonstrates the importance of bionanomaterials to biotechnology, biomedicine, and environmental remediation. Print ISBN: 978-1-4398-7641-1 eBook ISBN: 978-1-4398-7642-8 August 2013, 6-1/8 x 9-1/4, 490 pp. Suggested Price: $149.95 / £99.00
Stephen P. Morgan, Felicity R. Rose, and Stephen J. Matcher This practical book illustrates how to use optical imaging techniques and instrumentation for the fabrication, assessment, and longitudinal monitoring of regenerative medicine therapies. It covers optical coherence tomography, acousto-optic imaging, Raman spectroscopy, machine vision, bioluminescence, second harmonic generation microscopy, multi-photon microscopy, coherent anti-Stokes Raman scattering, fluorescence spectroscopy, and light scattering spectroscopy. Each chapter provides an overview of a particular technique, its advantages and limitations in terms of structural and functional information, and examples of applications in regenerative medicine. Print ISBN: 978-1-4398-5495-2 eBook ISBN: 978-1-4398-5496-9 August 2013, 7 x 10, 438 pp. Suggested Price: $129.95 / £82.00
Polymer and Polymer-Hybrid Nanoparticles From Synthesis to Biomedical Applications Stanislav Rangelov Asterios Pispas Polymeric and hybrid nanoparticles have received increased scientific interest in terms of basic research as well as commercial applications. This book covers an array of topics from polymer synthesis and macromolecular design to possible biomedical applications. The authors present a well-rounded picture of objects ranging from simple polymeric micelles to complex hybrid polymer-based nanostructures, detailing synthetic procedures, techniques for characterization and analysis, properties, and behavior in select solvents and dispersions. They summarize important developments in the field, condensing the relevant research into a comprehensive resource. Print ISBN: 978-1-4398-6907-9 eBook ISBN: 978-1-4398-6909-3 August 2013, 6-1/8 x 9-1/4, 499 pp. Suggested Price: $159.95 / £99.00
Nanomedical Device and Systems Design
Polymers for Vascular and Urogenital Applications
Challenges, Possibilities, Visions
Edited by
Edited by
Frank Boehm Independent Designer, Thunder Bay, Ontario, Canada
Shalaby W. Shalaby, Karen J.L. Burg, and Waleed Shalaby Series: Advances in Polymeric Biomaterials
This volume articulates the development and implementation of beneficial advanced nanomedical diagnostic and therapeutic devices and systems, which may have a strong potential toward enabling myriad paradigm shifts in the field of medicine. In addition, it presents conceptual and laboratory-derived examples of how sophisticated, highly efficient, minimally invasive, and cost-effective nanomedical diagnostic and therapeutic strategies might facilitate significantly increased accessibility to advanced medical procedures to assist those in both the developing and developed worlds. It also explores applications of nanomedicine in human augmentation, longevity, and space travel.
In a carefully crafted, multidisciplinary, skillfully focused format, this book covers attributes of polymers used for vascular, urological, and gynecological materials. It provides a brief analysis of how the use of polymers in vascular and urogenital applications has evolved in the past five decades and outlines their common and specific functional requirements. It features small, readable monographs that provide a brief description of the evolving role of a particular material, and present topics in highly integrated, well-balanced, authoritatively prepared segments on materials processing and in vitro and in vivo evaluation, complete with case studies.
Print ISBN: 978-0-8493-7498-2 November 2013, 7 x 10, 787 pp. Suggested Price: $179.95 / £114.00
Print ISBN: 978-1-4200-7694-3 eBook ISBN: 978-1-4200-7695-0 May 2012, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $189.95 / £120.00
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Edited by
Richard Schulz University of Pittsburgh, Pennsylvania, USA
Textbook
Ultrasonic and Electromagnetic NDE for Structure and Material Characterization Engineering and Biomedical Applications
Series: Rehabilitation Science in Practice Series
A collaboration between leading scientists, practitioners, and researchers at Carnegie Mellon University and the University of Pittsburgh, this book describes the development, evaluation, adoption, and commercialization of quality of life technologies. It takes an interdisciplinary team approach to the process of technology development for disabled and older persons and discusses the state of the art and future directions of technologies. The book provides direction on how to identify user needs and preferences, engage end-users in the design and development process, and evaluate and commercialize the technologies. Print ISBN: 978-1-4665-0534-6 eBook ISBN: 978-1-4665-0535-3 October 2012, 7 x 10, 334 pp. Suggested Price: $146.95 / £93.00
Edited by
Tribikram Kundu The University of Arizona, Tucson, USA
Most books on NDE focus either on the theoretical background or on advanced applications. Bridging the gap, this book brings together the principles, equations, and applications of ultrasonic and electromagnetic NDE in a single, authoritative resource. It begins with the fundamentals of mechanics and electromagnetic theory, derives the basic equations, and then, step by step, covers state-of-theart topics and applications. These include structural health monitoring, acoustic microscopy, terahertz imaging, and more. Written in plain language by some of the world’s leading experts, this book appeals to students as well as practicing engineers and researchers. Print ISBN: 978-1-4398-3663-7 eBook ISBN: 978-1-4398-3664-4 June 2012, 7 x 10, 890 pp. Suggested Price: $139.95 / £80.00
Textbook
Regenerative Engineering Edited by
Cato T. Laurencin and Yusuf Khan University of Connecticut Health Center, Farmington, USA
Regenerative engineering is the intersection of regenerative medicine and tissue engineering. Regenerative medicine focuses on the biological aspects of tissue regeneration via stem cells, factors, and cytokines, while tissue engineering focuses on the integration of materials science and life sciences. This book integrates these two areas, presenting each concept in the framework of regenerative engineering. Through the combination of fundamental lecturebased teaching and problem-based learning approaches, it is the goal of this textbook to develop students into future researchers capable of completing the translation of their work from the benchtop to the bedside. Print ISBN: 978-1-4398-1412-3 eBook ISBN: 978-1-4398-1413-0 June 2013, 7 x 10, 435 pp. Suggested Price: $99.95 / £63.99
Usability Testing of Medical Devices Michael E. Wiklund, P.E., Jonathan Kendler, and Allison Y. Strochlic Informative, practical, and engaging, this handbook covers how to conduct usability tests of medical devices. Recognizing that the intended readers are busy and disinclined to read lengthy textbooks, this book has been carefully designed to be concise and visual, allowing readers to jump from one section to another as needed. The book provides a general understanding of usability testing and reviews key concepts. It highlights the challenges of validating that protects against dangerous errors that could lead to patient injury and death. Print ISBN: 978-1-4398-1183-2 eBook ISBN: 978-1-4398-1184-9 December 2010, 6-1/8 x 9-1/4, 412 pp. Suggested Price: $79.95 / £51.99
Skin Bioscience Edited by
Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery
Toyoko Imae
Edited by
A Molecular Approach National Taiwan University of Science and Technology, Taipei
This book introduces skin bioscience with a specific focus on the molecular approach. Following the description of the fundamental structure and unique functionality of the skin, it examines the response of the skin to exterior stimulation. It also focuses on the beautification and regeneration of the skin. This book provides readers with the molecular knowledge of the skin and stimulates their interest in further investigation and development of skin bioscience. Print ISBN: 978-981-4364-95-9 October 2013, 6 x 9, 200 pp. Suggested Price: $149.95 / £95.00
Chengtie Wu, Jiang Chang, and Yin Xiao Bioceramics play an important role in repairing and regenerating defective or damaged bone. This volume reviews the latest advances in the field. Offering guidance for biomedical engineering researchers and material scientists, the book summarizes innovative concepts, bioceramic design, and methods for material synthesis and drug delivery. It covers design and fabrication of these materials, down to the nanoscale, and includes chapters on medical device engineering using these materials. The book is designed to enhance study and career development for those in this field and to facilitate further research and opportunities for new solutions. Print ISBN: 978-1-4665-5199-2 eBook ISBN: 978-1-4665-5200-5 March 2013, 6-1/8 x 9-1/4, 244 pp. Suggested Price: $189.95 / £99.95
For more information and a complete list of titles, visit us at www.crcpress.com
Biomaterials & Medical Devices / Biomedical Engineering
Quality of Life Technology Handbook
11
Advanced Materials for Joint Implants
Textbook
Giuseppe Pezzotti
Yang Cai
Biomedical Engineering
Kyoto Institute of Technology, Japan
Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
In an interdisciplinary approach that links orthopedic concepts and surface science, this book details cuttingedge research in bioceramics science, physical chemistry, biomedical optics, and nanomechanics. It covers some of the more conventional spectroscopic characterization techniques—including Raman and cathodoluminescence spectroscopy. These techniques have been used to unveil molecular scale phenomena of both chemical and mechanical origin occurring at the sliding surfaces of bioceramic joints. These concepts are of critical importance to researchers as they are relevant to the development of new biomaterials.
In everyday life, we often recognize patterns from adhoc sensors and make intuitive decisions. This process is known as ambient diagnostics. This textbook is written for emerging courses in biomedical engineering, electrical engineering, and computer science that explore intelligent software diagnostics from affordable devices, such as sensors on mobile phones, microphones, cameras, and gyroscopes. The text inspires readers to design and develop tools for personal health monitoring and diagnosis.
Print ISBN: 978-981-4316-88-0 eBook ISBN: 978-981-4364-39-3 September 2013, 6 x 9, 626 pp. Suggested Price: $179.95 / £114.00
Print ISBN: 978-1-4665-1041-8 February 2014, 6-1/8 x 9-1/4, 392 pp. Suggested Price: $99.95 / £63.99
Textbook
Advances in Therapeutic Engineering Edited by
Wenwei Yu, Subhagata Chattopadhyay, Teik-Cheng Lim, and U. Rajendra Acharya Therapeutic Engineering (TE) is a cutting-edge domain in today’s era of medical technology research. Through engineering algorithms that provide technological solutions, it aims to elevate the quality of life of disabled individuals. This volume describes various therapeutic processes and mechanisms currently applied to healthcare in a range of areas, including mobility, communications, hearing, vision, and mental health and cognition. From prosthetics to sensory substitution and medical robotics, the book will prove enlightening to researchers and practitioners in a host of disciplines who want to understand the recent advances achieved globally in the field of therapeutic engineering.
12
Ambient Diagnostics
Print ISBN: 978-1-4398-7173-7 eBook ISBN: 978-1-4398-7174-4 December 2012, 6-1/8 x 9-1/4, 496 pp. Suggested Price: $189.95 / £114.00
Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation Second Edition Robert B. Northrop University of Connecticut, Storrs, USA Series: Biomedical Engineering
This book helps biomedical engineers understand and design signal conditioning systems using analog integrated circuits. It explains the electronic components and subsystems—the “building blocks”—that are used in ECG, EEG, EMG, ERG, tomographic images, biochemical spectrograms, and other crucial medical applications. This second edition has been substantially updated and revised. It now features a glossary, new end-of-chapter problems, and three new chapters that address wireless patient monitoring using UHF telemetry; power amplifiers and their applications to biomedical instruments; and RFID, GPS, and ultrasonic tags used in ecological research. Print ISBN: 978-1-4398-6669-6 eBook ISBN: 978-1-4398-9883-3 March 2012, 7 x 10, 578 pp. Suggested Price: $125.95 / £81.00
Ambient Assisted Living
Articular Cartilage
Nuno M. Garcia, Joel Jose P.C. Rodrigues, Dirk Christian Elias, and Miguel Sales Dias
Kyriacos A. Athanasiou, Eric M. Darling, Grayson D. DuRaine, Jerry C. Hu, and A. Hari Reddi
Series: Rehabilitation Science in Practice Series
Written for students, practitioners, and users of Ambient Assisted Living (AAL), this comprehensive reference covers methods, concepts, systems, devices, and services that provide unobtrusive support for the daily needs of an assisted person. The reference also provides extensive coverage of applications, software, and information management for AAL, as well as coverage of the latest hardware and software for ergonomic design pertaining to AAL. A key concept covered within the reference is ambient intelligence, which refers to electronic environments that are sensitive and responsive to the presence of people. References are provided at the end of each chapter for additional study. Print ISBN: 978-1-4398-6984-0 April 2014, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $149.95 / £95.00
Articular cartilage injuries, known for their inability to heal, often degenerate inexplicably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. However, over the past two decades, there has been swift growth and development of new knowledge and technologies for cartilage formation, pathology, and repair. Written by worldclass experts, this book covers all the latest research and clinical applications related to cartilage tissue engineering, including the role of nanotechnology. Print ISBN: 978-1-4398-5324-5 eBook ISBN: 978-1-4398-5325-2 March 2013, 6-1/8 x 9-1/4, 439 pp. Suggested Price: $169.95 / £108.00
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Biochemical Sensors
Edited by
Mimicking Gustatory and Olfactory Senses
Stefano Federici and Marcia Scherer
Edited by
Series: Rehabilitation Science in Practice Series
Kiyoshi Toko
Assistive technology plays a fundamental role in facilitating the social integration of people with physical, sensory, communication, and cognitive disabilities. This handbook presents the assessment tools that are essential in a center for technical aid, where multidisciplinary teams match the technology to the person who needs it. The book also describes the roles of members of the assessment team and reviews cutting-edge technologies for rehabilitation and independent living. Emphasizing the well-being of the person with disabilities, it proposes an ideal model of the assessment process and outlines how the model can be applied in practice internationally.
Kyushu University, Fukuoka, Japan
An exploration of the interdisciplinary nature of biomedical products fabrication, this book is the first comprehensive study of sensors for gustatory and olfactory senses. These devices are fabricated on the basis of nanotechnology, materials science, bioengineering, biomedical engineering, electronic engineering, sensor technology, information science, chemistry, and biology. Lucidly written and eminently informative, it is a top-class reference for students and researchers in a wide variety of scientific fields and also for those active in the fields of foods, perfumery, medicine, and robotics.
Print ISBN: 978-1-4398-3865-5 eBook ISBN: 978-1-4398-3866-2 March 2012, 7 x 10, 484 pp. Suggested Price: $146.95 / £86.00
Print ISBN: 978-981-4267-07-6 eBook ISBN: 978-981-4303-42-2 September 2013, 6 x 9, 582 pp. Suggested Price: $249.95 / £159.00
Assistive Technology for Blindness and Low Vision
Bioengineered Nanomaterials
Edited by
Roberto Manduchi and Sri Kurniawan University of California, Santa Cruz, USA
Atul Tiwari University of Hawaii at Manoa, Honolulu, USA
Ashutosh Tiwari Linköping University, Sweden
Series: Rehabilitation Science in Practice Series
This book provides a comprehensive overview of the current state of the art in assistive technology for persons with visual impairment, as well as coverage into promising new research directions. Beginning with a brief overview of the pathology and psychophysical aspects of low vision and blindness, the text proceeds with indepth descriptions of current technology to support independent mobility and orientation, information access (printed information, tactile information, and computers), and life activities (education, work, entertainment), as well as future directions related to the technology for blindness and visual impairment. Print ISBN: 978-1-4398-7153-9 eBook ISBN: 978-1-4398-7155-3 October 2012, 6-1/8 x 9-1/4, 441 pp. Suggested Price: $125.95 / £81.00
Textbook
Basic Transport Phenomena in Biomedical Engineering Third Edition Ronald L. Fournier University of Toledo, Ohio, USA
Exploring fundamental engineering and life science principles to uncover key concepts in biomedical engineering transport phenomena, this volume begins with a review of the basics of thermodynamics. It then examines the physical properties of body fluids and the cell membrane before moving on to topics such as properties of blood, solute transport, pharmacokinetic analysis, extracorporeal devices, tissue engineering, and bioartificial organs. Each chapter ends with problems to help clarify the material. Print ISBN: 978-1-4398-2670-6 eBook ISBN: 978-1-4398-9662-4 August 2011, 7 x 10, 483 pp. Suggested Price: $109.95 / £55.99
Edited by
Biomedical Engineering
Assistive Technology Assessment Handbook
This book presents in-depth information on bioengineered nanomaterials currently being developed in leading research laboratories around the world. In particular, the book focuses on nanomaterials for biomedical applications. Renowned international researchers discuss nanoemulsions as a vaccine adjuvant, bioceramic nanomaterials in medical applications, nanoporous membranes for cell encapsulation therapy, and inorganic nanoparticle materials for the controlled release of drugs. They also explore nanomedicine in brain tumor treatment, nanoparticles for the treatment of solid tumors and metastasis, and silver nanoparticles toxicity testing and bioapplications, among many other topics. Print ISBN: 978-1-4665-8595-9 eBook ISBN: 978-1-4665-8596-6 August 2013, 7 x 10, 436 pp. Suggested Price: $179.95 / £114.00
Biofluid Dynamics of Human Body Systems Megh R. Goyal University of Puerto Rico, Mayagüez, USA (Retired Professor)
An easy-to-understand, one-stop manual on the fluid mechanics of human body systems, this book offers basic knowledge and techniques necessary to understand, design, develop, and evaluate a medical device. It includes the basic principles and applications, types, and mechanics of flow dynamics through twelve human body systems. It covers the biofluid dynamics of the respiratory system, the brain, the urinary system, the digestive system, and the maternal fetal system; explains how drugs are transported through the human body; and provides information on instrumentation and measurements of body fluids. Print ISBN: 978-1-926895-46-8 eBook ISBN: 978-1-4822-0333-2 September 2013, 6-1/8 x 9-1/4, 628 pp. Suggested Price: $149.95 / £95.00
For more information and a complete list of titles, visit us at www.crcpress.com
13
Biofluid Mechanics
Biological and Medical Sensor Technologies
The Human Circulation, Second Edition
Edited by
Krishnan B. Chandran, Stanley E. Rittgers, and Ajit P. Yoganathan
Krzysztof Iniewski
This classroom-tested text teaches students how fluid mechanics are applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition includes improved figures, additional examples, and more problems at the end of each chapter. It also presents a new chapter on the computational fluid dynamic analysis of human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas.
Series: Devices, Circuits, and Systems
Textbook
Biomedical Engineering
Print ISBN: 978-1-4398-4516-5 eBook ISBN: 978-1-4398-9817-8 February 2012, 6-1/8 x 9-1/4, 451 pp. Suggested Price: $109.95 / £69.99
Edited by a pioneer in the area of advanced semiconductor materials, this book contains contributions from experts who explore the development and use of sensors in biological and medical applications. It covers advanced sensing and communications, modeling of DNAderivative architecture, and the use of enzyme and quartz crystal microbalancebased biosensors. The book also addresses biosensors in human behavior measurement, sweat rate wearable sensors, and the future of medical imaging, including developments in spatial and spectral resolution of semiconductor detectors. Contributors discuss application of high-resolution CdTe detectors in gamma ray imaging and recent advances in positron emission tomography technology. Print ISBN: 978-1-4398-8267-2 eBook ISBN: 978-1-4665-5257-9 February 2012, 6-1/8 x 9-1/4, 412 pp. Suggested Price: $159.95 / £100.00
Biofunctional Surface Engineering
Biomechanics
Edited by
Edited by
Martin Scholz
Donald R. Peterson
LEUKOCARE AG, Munich, Germany
The lack of effective sterilization techniques for biologics has spawned discussions about the reduction of regulatory requirements which might impose significant safety risks. On the other hand, novel and safe technologies enable the coupling, stabilization, and protection of effector molecules in a way that allows terminal sterilization without loss of function. This book provides a comprehensive overview on the state of the art and the future of “biofunctional surface engineering” and is of major interest for all those working in the fields of medicine and medical devices.
14
CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada
Print ISBN: 978-981-4411-60-8 January 2014, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00
Principles and Practices University of Connecticut, Farmington, USA
Joseph D. Bronzino Simsbury, Connecticut, USA
Biomechanics: Principles and Practices draws on material from the biomechanics section of The Biomedical Engineering Handbook, Fourth Edition, and includes additional chapters containing highly relevant, cutting-edge material dealing with cellular mechanics. Edited by Donald R. Peterson and Joseph D. Bronzino, this comprehensive reference brings together contributions by world-class experts in the field. Offering an overview of major research topics in biomechanics, this is a useful resource for practitioners, scientists, and researchers in biomechanics as well as bioengineering graduate students studying biomechanics, human performance engineering, and human factors. Print ISBN: 978-1-4398-7098-3 April 2014, 7 x 10, 400 pp. Suggested Price: $139.95 / £89.00
Textbook
Biological and Bioenvironmental Heat and Mass Transfer Ashim K. Datta Cornell University, Ithaca, New York, USA
Providing a foundation in heat and mass transport, this book covers engineering principles of heat and mass transfer. The author discusses biological content, context, and parameter regimes and supplies practical applications for biological and biomedical engineering, industrial food processing, environmental control, and waste management. The book contains end-of-chapter problems and sections highlighting key concepts and important terminology. It offers cross-references for easy access to related areas and relevant formulas, as well as detailed examples of transport phenomena and descriptions of physical processes. It covers mechanisms of diffusion, capillarity, convection, and dispersion.
Biomechanics of Artificial Organs and Prostheses Megh R. Goyal University of Puerto Rico, Mayagüez, USA (Retired Professor) Series: Advances in Bioengineering Research and Applications, Volume 2
Artificial organs are one of the world’s greatest advancements in medicine. This book covers cardiopulmonary bypass surgery; artificial hearts and pacemakers; stenting and ballooning; artificial lungs, kidneys, and knees; dental protheses; and more. It is a one-stop source of basic knowledge and techniques necessary to understand, design, develop, and evaluate artificial organs and prostheses. It covers the basic principles and applications, types and mechanics, and biomaterials. It is a must for physicians, scientists, and educators. Print ISBN: 978-1-926895-84-0 December 2013, 6-1/8 x 9-1/4, 402 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-0-8247-0775-0 eBook ISBN: 978-0-203-91018-4 March 2002, 8-1/2 x 11, 424 pp. Suggested Price: $115.95 / £77.99
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Applications in the Martial Arts Emeric Arus, Ph.D. International Sendo-Ryu Karatedo Federation, Astoria, New York, USA
This book provides an overview of human motion studies—biomechanics—using martial arts as extensive examples and references to fundamental theory. It covers in depth the anatomical foundation of biomechanics, the biomechanical and physiological foundation of human motion, and fundamentals of biomechanics. The book begins with musculoskeletal anatomy of the most important muscles and their functions. The author describes the biomechanical and physiological foundations of human motion. He covers kinematics and kinetics—the core of biomechanics—and includes examples for martial arts and sports activities that emphasize the concepts described. Print ISBN: 978-1-4665-6323-0 eBook ISBN: 978-1-4665-6324-7 December 2012, 6-1/8 x 9-1/4, 559 pp., Soft Cover Suggested Price: $83.95 / £51.99
Biomedical Photonics Handbook Therapeutic and Advanced Biophotonics, Second Edition Edited by
Tuan Vo-Dinh Duke University, Durham, North Carolina, USA
Biomedical photonics is defined as the science of harnessing light and other forms of radiant energy to address problems in medicine and biology. The field has experienced explosive growth due to the noninvasive or minimally invasive nature and cost-effectiveness of photonic modalities in medical diagnostics and therapy. This third volume of the Biomedical Photonics Handbook, Second Edition focuses on therapeutic and future trends. It is an authoritative reference source for those involved in the research, teaching, learning, and practice of medical technologies. Print ISBN: 978-1-4200-8516-7 May 2014, 7 x 9, 800 pp., Soft Cover Suggested Price: $189.95 / £121.00
Biomedical Applications of Mesoporous Ceramics
Biomedical Technology and Devices
Drug Delivery, Smart Materials and Bone Tissue Engineering
Second Edition
María Vallet-Regí, Miguel Manzano García, and Montserrat Colilla
James E. Moore Jr Duncan J. Maitland
This book provides a comprehensive overview of silicabased mesoporous materials with special attention given to their use in drug delivery systems, sophisticated stimuli-responsive materials, and bone tissue engineering. The text provides a comprehensive overview of the basic aspects of the properties of mesoporous materials, with a focus on textural properties such as surface and porosity. Starting from this consolidated knowledge, it then addresses various aspects of more sophisticated stimuliresponsive materials, where drugs can be encapsulated inside the porous framework and then released when desired. The final chapters are dedicated to bone tissue engineering.
Series: Handbook Series for Mechanical Engineering
Print ISBN: 978-1-4398-8307-5 eBook ISBN: 978-1-4398-8308-2 November 2012, 6-1/8 x 9-1/4, 231 pp. Suggested Price: $146.95 / £93.00
Print ISBN: 978-1-4398-5959-9 eBook ISBN: 978-1-4398-6061-8 June 2013, 7 x 10, 820 pp. Suggested Price: $189.95 / £121.00
Biomedical Engineering Fundamentals
Biomimetics
Second Edition
Yoseph Bar-Cohen
Fully revised since its original publication, this reference illuminates the equipment, devices, and techniques used in modern medicine to diagnose, treat, and monitor human illnesses. With topics ranging from basic procedures like blood pressure measurements to cutting-edge imaging equipment, biological tests, and genetic engineering, the book is organized to navigate smoothly from simple procedures and concepts to more sophisticated and complex ones. Each section contains a description of the technique, its technical considerations, and its use according to its applications and relevant body systems.
Nature-Based Innovation JPL/Caltech, Pasadena, California, USA
Joseph D. Bronzino Donald R. Peterson University of Connecticut, Farmington, USA Series: The Biomedical Engineering Handbook, Third Edition
This first volume of The Biomedical Engineering Handbook, Fourth Edition provides comprehensive coverage of the latest research findings. Known as the bible of biomedical engineering, the handbook set the standard against which all other references of this nature are measured and found wanting. The new edition features a new co-author, coverage of medical ethics, historical perspective, and updated coverage in all sections. It provides an important resource for biomedical engineers and students. Print ISBN: 978-1-4398-2518-1 March 2014, 7 x 10, 1210 pp. Suggested Price: $189.95 / £121.00
Edited by
Biomedical Engineering
Biomechanics of Human Motion
A review of the current state of the art of biomimetics, this book documents key biological solutions that provide a model for innovations in engineering and science. Leading experts explore a wide range of topics, including artificial senses and organs; mimicry at the cell–materials interface; modeling of plant cell wall architecture; biomimetic composites; artificial muscles; biomimetic optics; and the mimicking of birds, insects, and marine biology. The book also discusses applications of biomimetics in manufacturing, products, medicine, and robotics; biologically inspired design as a tool for interdisciplinary education; and the biomimetic process in artistic creation. Print ISBN: 978-1-4398-3476-3 eBook ISBN: 978-1-4398-3477-0 September 2011, 7 x 10, 788 pp. Suggested Price: $179.95 / £112.00
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Biosignal Processing Principles and Practices Edited by
Biomedical Engineering
Hualou Liang, Joseph D. Bronzino, and Donald R. Peterson
An Evaluation Guide for Professionals
This book provides state-of-the-art coverage of contemporary methods in biosignal processing, with emphasis on brain signal analysis. The topics covered in this book reflect an ongoing evolution in biosignal processing. As biomedical datasets grow larger and more complicated, emerging signal processing methods to analyze and interpret these data have gained in importance. This book discusses the process for biosignal analysis and stimulates new ideas and opportunities for developing cutting-edge computational methods for biosignal processing, which will in turn accelerate laboratory discoveries into treatments for patients.
Maria Laura Mele, Simone Borsci, Masaaki Kurosu, and Stefano Federici
Edited by
Series: Rehabilitation Science in Practice Series
This book provides the necessary tools for the evaluation of the interaction between the user who is disabled and the computer system that was designed to assist that person. The book creates an evaluation process that is able to assess the user’s satisfaction with a developed system. Presenting a new theoretical perspective in the human computer interaction evaluation of disabled persons, it takes into account all of the individuals involved in the evaluation process.
Print ISBN: 978-1-4398-7143-0 eBook ISBN: 978-1-4398-7144-7 October 2012, 7 x 10, 202 pp. Suggested Price: $119.95 / £70.99
Print ISBN: 978-1-4665-1113-2 November 2013, 6-1/8 x 9-1/4, 295 pp. Suggested Price: $149.95 / £95.00
Computational Biomechanics of the Musculoskeletal System
Design Controls for the Medical Device Industry
Edited by
Second Edition
Ming Zhang Yubo Fan
Marie B. Teixeira QA/RA Compliance Connection, Inc., Odessa, Florida, USA
Beihang University, Beijing, China
Focusing on orthopedic and rehabilitation engineering applications, this comprehensive reference collects the latest research and cutting-edge techniques used in computational biomechanics. The book is divided into chapters based on body part: foot and ankle joint, knee joint, lower limb, hip joint, spine, and upper extremity. Each chapter covers basic anatomy of the body part and details the scientific questions and medical problems that are addressed by modeling. The book discusses the computational model development and techniques used, related experimental studies for model setup and validation, and clinical applications.
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Computer Systems Experiences of Users with and Without Disabilities
Print ISBN: 978-1-4665-8803-5 May 2014, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $129.95 / £82.00
Computer Access for People with Disabilities A Human Factors Approach
This second edition of a bestseller provides a comprehensive review of design control requirements, as well as techniques to ensure your design control program follows current industry practice. The text assists you in developing a program that not only satisfies US FDA Quality System Regulation (QSR) and ISO 9001 and 13485 standards, but also meets third-party auditor/investigator expectations. The author’s continual participation in FDA QSR inspections and Notified Body ISO audits is reflected in practical updates to all chapters and appendices of the book. Print ISBN: 978-1-4665-0354-0 November 2013, 6-1/8 x 9-1/4, 205 pp. Suggested Price: $169.95 / £108.00
Devices for Mobility and Manipulation for People with Reduced Abilities
New York Institute of Technology, New York, USA
Teodiano Freire Bastos-Filho, Dinesh Kumar, and Sridhar Poosapadi Arjunan
Series: Rehabilitation Science in Practice Series
Series: Rehabilitation Science in Practice Series, 7
Providing the information clinicians need to know in order to provide effective alternative computer access solutions to individuals with disabilities, this book presents technology for individuals with physical, cognitive, and sensory impairments, and for older adults. The text covers text entry devices, pointing devices, switch access, automatic speech recognition, and web accessibility. The book draws on research from the fields of rehabilitation engineering, occupational therapy, and human-computer interaction (HCI) and emphasizes fundamental concepts and principles that remain true regardless of which specific operating system or product is being used.
Exploring the details of mobility and manipulative technologies, this volume provides insight into current research trends and discusses technologies that are under development. Each chapter covers one specific technology, starting with a general introduction, followed by technical details and an assessment from the user viewpoint— including the user benefits, user suitability, cost, reliability, and required infrastructure. Each chapter also provides illustrations or photographs of the devices, making it accessible to lay and clinical audiences. The book also identifies shortcomings, current research related to the technology, and possible development opportunities.
Print ISBN: 978-1-4665-5371-2 eBook ISBN: 978-1-4665-5372-9 January 2013, 6-1/8 x 9-1/4, 339 pp. Suggested Price: $99.95 / £63.99
Print ISBN: 978-1-4665-8645-1 April 2014, 6-1/8 x 9-1/4, 184 pp. Suggested Price: $139.95 / £89.00
Richard C. Simpson
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Diagnostic Endoscopy
From Bioimaging to Biosensors
Edited by
Noble Metal Nanoparticles in Biodetection
BC Cancer Research Centre, Vancouver, British Columbia, Canada Series: Series in Medical Physics and Biomedical Engineering, 29
Combining material from a SPIE course on diagnostic endoscopy with the authors’ graduate-level course on biomedical optics, this work covers basic optics, details of design, and biomedical uses. It is written for researchers and graduate students in medical optics and biomedical engineering. The book uses extensive examples and case studies to illustrate the basics of endoscopic optics, the pros and cons of white light endoscopy and fluorescence endoscopy for diagnostic applications, and various endoscopic microscopy and spectroscopy imaging modalities. Print ISBN: 978-1-4200-8346-0 December 2013, 6-1/8 x 9-1/4, 272 pp. Suggested Price: $99.95 / £63.99
Edited by
Chau Lai-Kwan National Chung Cheng University, Chia-Yi, Taiwan
Huan-Tsung Chang National Taiwan University, Taipei
This book provides a comprehensive overview of the use of noble metal nanoparticles for bioimaging and biosensing. It starts with a review on the synthesis, characterization, optical properties, and bioconjugation of noble metal nanoparticles, followed by an introduction of various biodetection techniques based on noble metal nanoparticles. In between these topics, microfabrication of biosensing chips and the use of microfluidics to enhance biosensing performance are discussed. Print ISBN: 978-981-4267-24-3 eBook ISBN: 978-981-4303-10-1 October 2012, 6 x 9, 322 pp. Suggested Price: $149.95 / £95.00
Encyclopaedia of Medical Physics
Textbook
Edited by
Ronald L. Huston
Fundamentals of Biomechanics
Slavik Tabakov, Franco Milano, Sven-Erik Strand, Cornelius Lewis, and Perry Sprawls Co-published by the EMITEL consortium and supported by the IOMP, this all-encompassing reference contains nearly 2,800 cross-referenced entries relating to medical physics and associated technologies. Featuring over 100 contributors who are specialists in their respective areas, the encyclopaedia describes new and existing methods and equipment in medical physics. It covers x-ray diagnostic radiology, MRI, nuclear medicine, radiation protection, radiotherapy, and ultrasound imaging. Most articles include references, further reading, images, graphs, formulas, and examples. Print ISBN: 978-1-4398-4652-0 eBook ISBN: 978-1-4822-2484-9 December 2012, 8-1/2 x 11, 908 pp. Suggested Price: $755.00 / £481.00
University of Cincinnati, Ohio, USA
This textbook provides a comprehensive survey of how the principles of mechanics are applied to human systems and organs. After a review of terminology, a summary of human anatomy, and a presentation of anthropometric data, the text discusses methods for biomechanical analyses including essential mathematics, mechanics, and modeling techniques. It then covers tissue biomechanics, kinematics, and dynamics of human body models, and applications such as lifting, walking, swimming, and accident victim simulation. Each chapter contains reference lists for more in-depth study and problems sets with solutions. Print ISBN: 978-1-4665-1037-1 eBook ISBN: 978-1-4822-1155-9 April 2013, 7 x 10, 470 pp. Suggested Price: $99.95 / £63.99
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Epidemiology of Electromagnetic Fields
Handbook of Clinical Nanomedicine
Edited by
From Bench to Bedside
Martin Roosli Swiss Tropical and Public Health Institution, Basel, Switzerland
Generally, all types of electromagnetic fields (EMF) are suspected to harm human health. A substantial number of epidemiological studies have addressed possible effects on human health. Nevertheless, there is an ongoing public and scientific controversy about possible health effects. This book gives an overview of epidemiological methods that have been used for EMF research. The first part of the book introduces epidemiological concepts and principles, along with appropriate examples and practical usage. The second part details the state of scientific knowledge for some controversial issues in EMF research. Print ISBN: 978-1-4665-6816-7 April 2014, 6-1/8 x 9-1/4, 350 pp. Suggested Price: $149.95 / £95.00
Biomedical Engineering
Haishan Zeng
Edited by
Raj Bawa, Gerald F. Audette, and Israel Rubinstein The handbook, divided into four sections, provides a comprehensive road map of basic research in nanomedicine as well as clinical applications and commercialization activities. Each of the 45-plus chapters contains 10–20 key words, extensive tables, color figures, future projections, and an extensive list of references. The handbook is essential reading for the novice and expert alike in fields such as medicine, law, biotechnology, pharmaceutical sciences, engineering, biomedicine, policy, future studies, ethics, intellectual property law, licensing, and toxicology. Print ISBN: 978-981-4316-17-0 May 2014, 6 x 9, 800 pp. Suggested Price: $495.00 / £315.00
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Handbook of Intelligent Scaffold for Tissue Engineering and Regenerative Medicine
Heart Rate Variability (HRV) Signal Analysis
Edited by
Edited by
Gilson Khang
Markad V. Kamath, Mari Watanabe, and Adrian Upton
Chonbuk National University, Jeonju, North Korea
Biomedical Engineering
Providing detailed knowledge about fullerene nanowhiskers and the related low-dimensional fullerene nanomaterials, this book introduces tubular nanofibers made of fullerenes, “fullerene nanotubes,” as well as the single crystalline thin film made of C60, called “fullerene nanosheet.” It is the first publication featuring the fullerene nanowhiskers made of C60, C70, C60 derivatives, and so forth. It demonstrates the synthetic method (liquid–liquid interfacial precipitation method) and the physical and chemical properties such as electrical, mechanical, optical, magnetic, thermodynamic, and surface properties of fullerene nanowhiskers, including their electronic device application. Print ISBN: 978-981-4267-85-4 eBook ISBN: 978-981-4267-86-1 February 2012, 6 x 9, 974 pp. Suggested Price: $499.95 / £318.00
Handbook of Medical Device Regulatory Affairs in Asia
This cutting-edge reference examines how beat-to-beat variations in heart rate and blood pressure provide a window into the health of the autonomic nervous system. The book consists of a how-to section, detailing classical and recent techniques that have been developed for analyzing heart-rate and blood pressure variability, and a practical applications section that discusses the utility of heart rate variability for various clinical situations- including patient monitoring in obstetrics, surgery, and intensive care units- and assessment of disease severity in chronic disorders such as stroke, depression, and Parkinson’s disease. Print ISBN: 978-1-4398-4980-4 eBook ISBN: 978-1-4665-7605-6 October 2012, 7 x 10, 532 pp. Suggested Price: $159.95 / £100.00
Hydrated Materials
Edited by
Applications in Biomedicine and the Environment
Jack Wong
Yoshitaka Nakanishi
Asia Regulatory Professional Association, Kwun Tong, Kowloon, Hong Kong
Raymond Tong Kaiyu Hong Kong Polytechnic University, Hung Hom, Kowloon
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Clinical Applications
With a focus on Asian countries, this handbook covers medical device regulatory systems in different regions, ISO standards for medical devices, clinical trial and regulatory requirements, and documentation for application. Each chapter provides substantial background materials relevant to the particular area to provide readers with a better understanding of regulatory affairs. With contributions from authors working with regulatory bodies around the world, the handbook explains the basics of the Asian market and how to best access it. It also guides product developers through the global regulatory environment. Print ISBN: 978-981-4411-21-9 eBook ISBN: 978-981-4411-22-6 March 2013, 6 x 9, 616 pp. Suggested Price: $149.95 / £95.00
Kumamoto University, Japan
Water covers more than 70% of the earth’s surface and is an essential and major component of all living matter. However, artificially hydrated materials, including hydrophilic materials, are far fewer than one might expect. Currently, these materials are in a state of development for applications in fields such as biomedicine, environmental engineering, and industrial engineering. So what do artificially hydrated materials hold for the future? This book is a great introduction to hydrated materials, presenting academic and practical content that gives a feel of theoretical as well as real-world problems. Print ISBN: 978-981-4463-22-5 January 2014, 6 x 9, 250 pp. Suggested Price: $149.95 / £95.00
Handbook of Personalized Medicine
Textbook
Advances in Nanotechnology, Drug Delivery and Therapy
Albert Folch
Edited by
Ioannis S. Vizirianakis Aristotle University of Thessaloniki, Greece
This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical settings that creates the fertile ground for the practical utility of personalized medicine decisions and enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, and information-based medicine.
Introduction to BioMEMS University of Washington, Seattle, USA
This classroom-tested book—in color throughout —covers the whole breadth of this dynamic field, including classical microfabrication, microfluidics, tissue engineering, cell-based and noncell-based devices, and implantable systems. It gives readers a real sense of how the field has grown by providing historical perspectives and covering the state of the art. The text contains problem sets, design challenges, key references, and over 400 color figures, most of which are from the original researchers. Downloadable PowerPoint slides are available for instructors. Print ISBN: 978-1-4398-1839-8 eBook ISBN: 978-1-4398-1840-4 August 2012, 7 x 10, 528 pp. Suggested Price: $93.95 / £59.99
Print ISBN: 978-981-4411-19-6 September 2013, 6 x 9, 400 pp. Suggested Price: $199.95 / £127.00
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Introduction to Physics in Modern Medicine Second Edition Suzanne Amador Kane Haverford College, Pennsylvania, USA
Fully updated, this volume builds on the bestselling original to provide medical and physics students with an exploration of the physics-related applications found in state-of-the-art medical centers. Requiring very little knowledge of physics, biology, or chemistry and keeping mathematics to a minimum, the application-dedicated chapters adhere to simple and self-contained qualitative explanations that make use of examples and illustrations. With an enhanced emphasis on digital imaging and computers in medicine, the text gives readers a fundamental understanding of the practical application of each. Supporting material includes an author-maintained website. Print ISBN: 978-1-58488-943-4 eBook ISBN: 978-1-58488-944-1 April 2009, 6-1/8 x 9-1/4, 448 pp., Soft Cover Suggested Price: $65.95 / £41.99
Textbook
A Laboratory Course in Tissue Engineering Melissa Kurtis Micou
Second Edition, Two Volume Set Spatial, Time, and Mechanical Measurement Edited by
John G. Webster University of Wisconsin-Madison, USA
Halit Eren Curtin University, Bentley, Australia Series: Electrical Engineering Handbook
Edited by renowned instrumentation experts, this new edition of a bestselling handbook brings together nearly 150 contributors covering all aspects of the design and implementation of instrumentation. It describes the use of instruments and techniques for performing practical measurements in engineering, physics, chemistry, and the life sciences. Organized according to measurement problem, each section addresses the different ways of making a measurement for a given variable. Each chapter is completely updated and presents basic information, a detailed mathematical treatment, advanced applications, evaluative options, and areas for future studies. Print ISBN: 978-1-4398-4883-8 January 2014, 7 x 10, 3600 pp. Suggested Price: $299.95 / £191.00
Also available as individual volumes
University of California, San Diego, USA
Dawn Kilkenny University of Toronto, Ontario, Canada
This book fills the need for a hands-on lab manual for tissue engineering instruction. Providing more than a semester’s worth of activities, it contains fifteen standalone experiments based on both classic and modern approaches. Experiments encompass a set of widely applicable techniques: cell culture, microscopy, histology, immunohistochemistry, mechanical testing, soft lithography, and common biochemical assays. In addition to teaching these specific techniques, the experiments emphasize engineering analysis, mathematical modeling, and statistical experimental design. To minimize lab costs, experiments use equipment commonly found in labs equipped for tissue culture. Print ISBN: 978-1-4398-7893-4 eBook ISBN: 978-1-4398-7894-1 August 2012, 6-1/8 x 9-1/4, 304 pp., Soft Cover Suggested Price: $62.95 / £40.99
Textbook
A Laboratory Manual in Biophotonics Vadim Backman, Adam Wax, and Hao Zhang The increasing use of optical techniques for biomedical applications has led to significant interest in biophotonics. From its basic concepts to more advanced topics and applications, this book provides a complete guide to biophotonics. The author offers both descriptive and quantitative perspectives as well as a comprehensive overview of major areas of research in the field. The text includes coverage of topics such as light tissue interaction, optical instrumentation, microscopic and macroscopic tissue imaging, tissue spectroscopy, therapeutic applications of optics, and molecular imaging. Print ISBN: 978-1-4398-1051-4 May 2014, 7 x 10, 500 pp. Suggested Price: $89.95 / £57.99
Measurement, Instrumentation, and Sensors Handbook
Biomedical Engineering
Textbook
Measurement, Instrumentation, and Sensors Handbook, Second Edition Spatial, Mechanical, Thermal, and Radiation Measurement Print ISBN: 978-1-4398-4888-3 January 2014, 7 x 10, 1640 pp. Suggested Price: $149.95 / £95.00
Measurement, Instrumentation, and Sensors Handbook, Second Edition Electromagnetic, Optical, Radiation, Chemical, and Biomedical Measurement Print ISBN: 978-1-4398-4891-3 January 2014, 7 x 10, 1954 pp. Suggested Price: $199.95 / £127.00
Mechanics of Cellular Bone Remodeling Coupled Thermal, Electrical, and Mechanical Field Effects Qing-Hua Qin Australian National University, Canberra, Acton, Australia
Research on bone remodeling has resulted in much new information and has led to improvements in design and biomedical practices. This volume presents a unified exploration of recent advances, giving readers a sound understanding of bone remodeling and its mathematical representation. Beginning with a description of the basic concept of bone remodeling from a mathematical point of view, the book details the development of each of the techniques and ideas. From there it progresses to the derivation and construction of multifield and cellular bone remodeling and shows how they arise naturally in response to external multifield loads. Print ISBN: 978-1-4665-6416-9 eBook ISBN: 978-1-4665-6417-6 January 2013, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $139.95 / £89.00
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19
Biomedical Engineering
Mechanobiology of the Endothelium
Medical Equipment Management
Edited by
Keith Willson
Helim Aranda-Espinoza
Principal Research Fellow, National Heart and Lung Institute, Imperial College, London, UK
The endothelium is an excellent example of where biology meets physics and engineering. It must convert mechanical forces into chemical signals to maintain homeostasis. It also controls the immune response, drug delivery through the vasculature, and cancer metastasis. Basic understanding of these processes is starting to emerge and the knowledge gained from research is now being used in applications from drug delivery to imaging modalities. This book reviews current knowledge in mechanobiology of the endothelium and its implications for the development of theranostic devices.
Keith Ison
Print ISBN: 978-1-4822-0724-8 February 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $139.95 / £89.00
Slavik Tabakov Consultant Medical Physicist, Department of Medical Physics, King’s College Hospital Foundation Trust and Programme Director, Medical Engineering and Physics, King’s College London, UK Series: Series in Medical Physics and Biomedical Engineering, 30
Offering insight into the problems and challenges of managing medical equipment within a healthcare system, this book helps readers develop an understanding of the business process and increase awareness of how maintenance of equipment is influenced by its design. It details the equipment management process: demonstration of need, funding, procurement, acceptance testing, asset register maintenance, user training and support, routine and breakdown maintenance, risk management, disinfection, incident reporting, device modifications and trials, and condemning and safe disposal of equipment. Print ISBN: 978-1-4200-9958-4 December 2013, 6-1/8 x 9-1/4, 334 pp. Suggested Price: $79.95 / £49.99
Medical Applications of Artificial Intelligence Edited by
Medical Robotics Handbook Sanja Dogramadzi University of the West of England, Bristol, UK
Arvin Agah University of Kansas, Lawrence, USA
Artificial Intelligence (AI) techniques have been successfully applied to the medical domain, and AI systems are being integrated into healthcare. Consistent and easily mass produced, AI systems can make providing healthcare more accurate, less expensive, more available, and more efficient. Organized into three sections—AI techniques, applications, and medical domains—this book covers the history, present, and future of AI systems in the medical system.
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Head of Medical Physics, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
Ravi Vaidyanathan University of Bristol, UK
The field of medical robotics is poised for significant growth in the immediate future. A wide range of new products are expected, from rehabilitation robots and service robots for the elderly and physically challenged to surgical mechanisms for minimally invasive surgery, new tools in informatics for immediate physician access to patient records, and tele-operated devices for field first aid. This comprehensive book serves as an introduction for those new to the field and as an invaluable desk reference for experienced professionals.
Print ISBN: 978-1-4398-8433-1 eBook ISBN: 978-1-4398-8434-8 November 2013, 7 x 10, 526 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4398-8143-9 April 2014, 7 x 10, 800 pp. Suggested Price: $179.95 / £114.00
Medical Devices and Systems
MEMS
Second Edition
Fundamental Technology and Applications
Edited by
Joseph D. Bronzino Donald R. Peterson University of Connecticut, Farmington, USA Series: The Biomedical Engineering Handbook, Third Edition
This is the second volume of The Biomedical Engineering Handbook, Fourth Edition. Providing comprehensive coverage of the latest research findings, this volume describes each type of sensor and discusses the important issues surrounding them. It looks at physical and chemical sensors and considers their applications in diagnosis and patient monitoring. The editors integrate medical ethics throughout the volume and examine emerging trends. Print ISBN: 978-1-4398-2525-9 March 2014, 7 x 10, 892 pp. Suggested Price: $189.95 / £121.00
Edited by
Vikas Choudhary Krzysztof Iniewski CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada Series: Devices, Circuits, and Systems
This book brings together groundbreaking research in MEMS technology and explores a wide range of novel applications enabled by the technology. International experts from industry and academia explain the theoretical background and share insights on applying the technology. Covering the historical evolution and recent trends, they examine gyroscopes, ambient energy harvesting, interconnects, resonators, micro hot-plate devices, wearable sensor assemblies, wireless microactuators, and much more. The contributors identify challenges and pose questions that need to be resolved, paving the way for further research and new applications. Print ISBN: 978-1-4665-1581-9 eBook ISBN: 978-1-4665-1582-6 June 2013, 7 x 10, 478 pp. Suggested Price: $149.95 / £95.00
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Micro- and Nanobubbles
Molecular Engineering
Fundamentals and Applications
Edited by
Hideki Tsuge
Joseph D. Bronzino Donald R. Peterson
Keio University, Tokyo, Japan
University of Connecticut, Farmington, USA
The field of micro- and nanobubbles has shown a strong potential for growth and is frequently highlighted in the news. Micro- and nanobubbles have many applications in a variety of fields including engineering, agriculture, environment, food, and medicine. This book is divided into three parts for the convenience of the readers: fundamentals, applications of microbubbles, and applications of nanobubbles. The book comprehensively discusses these topics and presents the possibility of micro- and nanobubbles as a new technology that can be utilized globally.
This book is the fourth volume of The Biomedical Engineering Handbook, Fourth Edition. This work has become the definitive “Bible” of the field of biomedical engineering. As such, it has served as a major reference for all practicing biomedical engineers and students. This volume has updated material throughout. In addition, it contains the majority of totally new sections such as Stem Cell Engineering and Personalized Medicine.
Print ISBN: 978-981-4463-10-2 March 2014, 6 x 9, 450 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4398-2527-3 March 2014, 7 x 10, 1480 pp. Suggested Price: $189.95 / £121.00
Microfluidics and Nanotechnology
Myocardial Tissue Engineering
Biosensing to the Single Molecule Limit
Edited by
Tatsuya Shimizu and Katsuhisa Matsuura
Biomedical Engineering
Edited by
Tokyo Women’s Medical University, Japan
Edited by
Eric Lagally Lagally Consulting, Seattle, Washington, USA
Krzysztof Iniewski CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada Series: Devices, Circuits, and Systems, 27
This book represents a snapshot of the state of the art from the world’s leading microfluidics and nanotechnology laboratories. The combination of different materials at both of these length scales is driving a powerful new set of scientific inquiries that have to date been impossible to address using other technologies. It focuses on the combination of soft materials (polymers, elastomers) with “hard” materials like semiconductors, metals, and glass to form integrated detection systems for biological and chemical targets. Print ISBN: 978-1-4665-9490-6 May 2014, 6-1/8 x 9-1/4, 328 pp. Suggested Price: $169.95 / £108.00
This book broadly summarizes myocardial tissue engineering and regenerative medicine, which consists of myocardial cell sources, cell therapy for damaged hearts, and tissue engineering technologies for fabricating beating hearts. It focuses on myocardial cell source, cardiac cells differentiated from embryonic stem (ES)/induced pluripotent stem (iPS) cells. Several chapters highlight innovative technologies developed to overcome the vascularization problem. Remarkable results obtained in the past and the present and challenges for the future in myocardial tissue engineering research field are described in the book. Print ISBN: 978-981-4411-31-8 January 2014, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00
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Microsurgery
Nanomedicine in Drug Delivery
Advances, Simulations, and Applications
Edited by
Arun Kumar, Heidi M. Mansour, Adam Friedman, and Eric R. Blough
Edited by
Toshio Fukuda Nagoya University, Japan
Carlos Tercero Nagoya University, Japan
This book explains, using the example of endovascular intervention, the development of in vitro simulators for biomedical applications based on the scientific context in the robotics area and the explanation of the medical procedure to be simulated. It presents modeling methods for in vitro representation of human tissue and for representing tissue integrity during endovascular surgery simulation. Additionally, applications of this in vitro vasculature modeling technology are presented: flow control for human blood pressure simulation, computer fluid dynamics simulations using vasculature morphology, catheter insertion robot control and vasculature imaging based on magnetic trackers, and tailor-made scaffolds for blood vessel regeneration.
Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit while limiting unwanted side effects. This book gives an overview of aspects of nanomedicine to help readers design and develop novel drug delivery systems and devices that build on nanoscale technologies. Contributors explore the use of nanoparticles in inhalation aerosols, nanodermatology, wound healing, bioimaging, anticancer drug delivery, ocular drug delivery, and more. They also discuss nanotoxicity and safety studies. Print ISBN: 978-1-4665-0616-9 eBook ISBN: 978-1-4665-0617-6 June 2013, 6-1/8 x 9-1/4, 469 pp. Suggested Price: $159.95 / £99.00
Print ISBN: 978-981-4364-69-0 eBook ISBN: 978-981-4364-70-6 April 2012, 6 x 9, 300 pp. Suggested Price: $179.95 / £114.00 For more information and a complete list of titles, visit us at www.crcpress.com
Nanotechnology for the Delivery of Therapeutic Nucleic Acids Edited by
Dan Peer
Edited by
Beth A. Winkelstein
The authors explore the state of the art in delivery strategies using lipids, polymers, chemical conjugates, nucleic acid (NA) aptamers, and proteins. They strongly emphasize issues and aspects that are of essence to the pharmaceutical industry in areas such as stability, general toxicity, immunetoxicity, pharmacokinetics, and the efficacy and validation of new drug targets in vivo by using unique approaches based on exquisite nanotechnology strategies. The contributing authors are world leaders in the field of nanotechnology for NA delivery and founders of different approaches.
This book presents state-of-the-art developments of orthopaedic biomechanics across tissues in the musculoskeletal system at all size scales and with direct relevance to engineering and clinical applications. Discussing the relationship between mechanical loading, function, and biological performance, it first reviews basic structure-function relationships for most major orthopaedic tissue types followed by the most relevant structures of the body. It then addresses multiscale modeling and biologic considerations. It concludes with a look at applications of biomechanics, focusing on recent advances in theory, technology, and applied engineering approaches.
Print ISBN: 978-981-4411-04-2 eBook ISBN: 978-981-4411-05-9 March 2013, 6 x 9, 240 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4398-6093-9 eBook ISBN: 978-1-4398-6094-6 December 2012, 7 x 10, 639 pp. Suggested Price: $189.95 / £120.00
Textbook
Patterns in Excitable Media
Tel Aviv University, Israel
Biomedical Engineering
Numerical Methods for Chemical Engineers Using Excel, VBA, and MATLAB Victor J. Law Tulane University, New Orleans, Louisiana, USA
Since many practical engineering problems must be solved numerically, this text provides instruction on using numerical methods and Excel®/VBA for chemical and biomolecular engineering problems covering a broad range of application areas. It also includes an introduction to MATLAB® that is made easier to learn after studying the programming tools in previous chapters. Each chapter contains examples that show in detail how a particular numerical method or programming methodology can be implemented. The chapters also contain end-of-chapter exercises with solutions provided.
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Orthopaedic Biomechanics
Print ISBN: 978-1-4665-7534-9 eBook ISBN: 978-1-4665-7940-8 March 2013, 6-1/8 x 9-1/4, 247 pp. Suggested Price: $59.95 / £38.99
Orthopaedic Biomaterials in Research and Practice Second Edition Kevin L. Ong Exponent Inc., Philadelphia, Pennsylvania, USA
Jonathan Black Clemson University (Professor Emeritus), South Carolina, USA
Scott Lovald Exponent Inc., Menlo Park, California, USA
Extensively revised, this text explores the biomaterials aspects of research and treatment of injuries, disabilities, and diseases of the musculoskeletal system, emphasizing properties of natural soft and hard tissues and the materials used to replace or treat them, and the interactions between native tissues and man-made (engineered) materials. It is intended for use in both teaching and self-study settings. The work introduces materials science as applied to medical research and treatment (biomaterials) for students and practitioners who may lack formal training in engineering.
Genesis, Dynamics and Control S. Sridhar Sitabhra Sinha Institue of Mathematical Sciences, Chennai, India
This book covers recent developments in the interdisciplinary field of dynamics and control of patterns in nonlinear biological systems described by excitable media models. Using examples of many reallife systems, it explores the impact of pattern dynamics on the structural and functional heterogeneities in the system. The book also discusses low-amplitude control schemes for eliminating patterns from an excitable medium, such as lifethreatening cardiac arrhythmia. Codes for numerical simulation are provided in the appendix. Print ISBN: 978-1-4665-5283-8 May 2014, 6-1/8 x 9-1/4, 310 pp. Suggested Price: $89.95 / £57.99
Textbook
Physical Chemistry for Engineering and Applied Sciences Frank R. Foulkes This book is the result of more than 30 years of teaching by the author of a one-semester course in physical chemistry to first-year students at the University of Toronto. The enrollment varied from 300 to 800 students per year over the years. The book is unique in that it provides the detailed development of the equations, which can be followed relatively easily even with only moderate mathematical skills and backgrounds. The book provides interesting and inspiring examples, as well as many problems and solutions. Print ISBN: 978-1-4665-1846-9 eBook ISBN: 978-1-4665-5115-2 September 2012, 7 x 10, 703 pp. Suggested Price: $89.95 / £59.99
Print ISBN: 978-1-4665-0350-2 January 2014, 7 x 10, 476 pp. Suggested Price: $179.95 / £114.00
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Fundamentals and Clinical Applications Edited by
Eduardo Moros Moffitt Cancer Center, Tampa, Florida, USA
Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of thermal therapy. An overview of the fundamentals shows how use of controlled heat in medicine and biology involves electromagnetics, acoustics, thermodynamics, heat transfer, and imaging sciences. The book discusses challenges in the use of thermal energy on living tissues and explores the genetic, cellular, and physiological responses that can be employed in the fight against cancer from the physicist/engineer’s perspective. It also highlights recent advances, including the treatment of solid tumors using image-guided thermal therapy, microbubbles, nanoparticles, and other cutting-edge techniques.
Textbook
Principles and Applications of Therapeutic Ultrasound in Healthcare Yufeng Zhou Nanyang Technological University, Singapore
Therapeutic uses of ultrasound include ablation of kidney stones and tumors and newer applications, such as drug delivery and denervation. Suitable as a textbook or as a quick reference for medical device engineers, research scientists, and healthcare professionals, this text systemically introduces the concepts, principles, construction, and application of therapeutic ultrasound devices. It discusses the fundamental physical principles of biomedical acoustics, ultrasound calibration methods, structures of commercially available therapeutic ultrasound systems, and various applications of ultrasound therapy in clinics. Print ISBN: 978-1-4665-1027-2 June 2014, 7 x 10, 392 pp. Suggested Price: $149.95 / £89.00
Print ISBN: 978-1-4398-4890-6 eBook ISBN: 978-1-4398-4892-0 December 2012, 8-1/2 x 11, 375 pp. Suggested Price: $159.95 / £100.00
Textbook
Physiology, Biophysics, and Biomedical Engineering
Pulmonary Nanomedicine Diagnostics, Imaging, and Therapeutics
Edited by
Edited by
Andrew W. Wood
Neeraj Vij
Swinburne University of Technology, Hawthorn, Victoria, Australia
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Series: Series in Medical Physics and Biomedical Engineering
This book explores engineered nanomaterials’ (ENM) pulmonary effects and familiarizes readers with unique aspects of nanomaterial application and research. Focusing on the diagnostic and therapeutic utilities of nanomaterials in different lung diseases, it discusses applications of nanotechnology for the treatment of airway diseases such as asthma, allergy, chronic obstructive pulmonary diseases, cystic fibrosis, and lung cancer. In an attempt to synchronize the efforts of pulmonary biologists, chemists, and clinicians in developing novel nano-based tools for airway diseases, the book also discusses the strategies to overcome the pathophysiological and technical barriers.
Showing how biophysics and biomedical engineering have advanced modern medicine, this text provides a multidisciplinary understanding of biological phenomena and the instrumentation for monitoring these phenomena. It also explores the application of physics and engineering methods to medicine and biology. The book includes a range of numerical problems with worked solutions and offers MATLAB® code for advanced mathematical analysis of physiological and clinical monitoring systems. A solutions manual is available with qualifying course adoption. Print ISBN: 978-1-4200-6513-8 eBook ISBN: 978-1-4398-9136-0 February 2012, 7 x 10, 782 pp. Suggested Price: $104.95 / £51.99
Print ISBN: 978-981-4316-48-4 eBook ISBN: 978-981-4364-14-0 August 2012, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00
Preventing Medical Device Recalls
Quality and Safety in Radiotherapy
Dev Raheja
Edited by
Based on the author’s extensive experience in the medical devices and manufacturing engineering industries, this book can save medical device companies millions of dollars by preventing many deaths and costly recalls. It is the first to show how to control safety risks, starting from specifications to safely retiring the products without harm to the environment. The book covers medical device requirements, preventing recalls during specification writing, risk assessment and management, preventing recalls during design and development, and much more. Print ISBN: 978-1-4665-6822-8 May 2014, 7 x 10, 400 pp., Soft Cover Suggested Price: $99.95 / £63.99
Todd Pawlicki, Peter Dunscombe, Arno J. Mundt, and Pierre Scalliet The first text to focus solely on quality and safety in radiotherapy, this work encompasses not only traditional technically oriented quality assurance activities, but also general approaches regarding quality and safety. It includes contributions from experts both inside and outside the field to discuss the processes and the people delivering the service. The contributors discuss Lean thinking, look at reactive and prospective error management techniques, and review various techniques to monitor, assure, and improve quality. The book also provides explicit details of quality control relating to equipment and patientspecific issues. Print ISBN: 978-1-4398-0436-0 eBook ISBN: 978-1-4398-0437-7 December 2010, 8-1/2 x 11, 643 pp. Suggested Price: $154.95 / £98.00
For more information and a complete list of titles, visit us at www.crcpress.com
Biomedical Engineering
Physics of Thermal Therapy
23
Rehabilitation Goal Setting
Scaffolds for Tissue Engineering
Theory, Practice and Evidence Richard Siegert
Biological Design, Materials and Fabrication
King’s College London, UK
Edited by
William Levack University of Otago, Wellington, New Zealand Series: Rehabilitation Science in Practice Series
Biomedical Engineering
Written to provide clinicians, educators, researchers, and students in rehabilitation with a comprehensive overview of the theory, practice, and evidence base of goal setting, this first-ofits kind reference provides an authoritative, state-of-the-art knowledge of the practice. The authors cover a broad range of different approaches to goal setting, with input from experts from North America, Europe, and Australia. Written under the assumption that rehabilitation is about understanding people in their social context and developing strategies for maximizing social participation, this book is applicable to patients with stroke, traumatic brain injury, neurological disorders, spinal cord injury, and other conditions. Print ISBN: 978-1-4398-6329-9 June 2014, 7 x 10, 600 pp. Suggested Price: $139.95 / £95.00
University of Trento, Italy
This book illustrates design principles for scaffolds for tissue engineering with particular relevance to the biological requirements needed to control and drive the biological cross-talk, and reviews materials, fabrication, and validation methods. The book is mainly addressed to graduate and post-graduate students who are approaching tissue engineering, or experienced researchers who wish to have condensed but comprehensive information on materials, fabrication techniques, biological principles, and design criteria. The contributors are among the scientific leaders in their respective fields. Print ISBN: 978-981-4463-20-1 May 2014, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00
Reliable Design of Medical Devices
Stem Cell Engineering
Third Edition
Edited by
Richard C. Fries
David Schaffer, Joseph D. Bronzino, and Donald R. Peterson
ISORel, Inc., Fitchburg, Wisconsin, USA
Following in the footsteps of the bestselling second edition, this book shows you how to improve reliability in the design of advanced medical devices. The organization of the book now mirrors the typical product development process, from the concept, feasibility, and design phases through to verification and validation, design transfer and manufacturing, and field activity. Updated throughout, it reflects recent changes in the medical device field, including software development and hardware test procedures. This practical, hands-on book guides you in preparing, designing, and testing medical devices more effectively.
24
Claudio Migliaresi and Antonella Motta
Print ISBN: 978-1-4398-9491-0 eBook ISBN: 978-1-4398-9494-1 September 2012, 6-1/8 x 9-1/4, 501 pp. Suggested Price: $189.95 / £120.00
Principles and Practices
With contributions from pioneers and experts, this book provides a broad overview of the challenges of stem cell engineering. It discusses advances made during the last decade that have led to increasingly defined culture systems for growing human ES cells, starting from co-culture with feeder cells in the presence of serum to growth on synthetic substrates in a defined medium. The book highlights recent advances in the understanding of the cellular and molecular composition of the hematopoietic stem cell niche, as well as approaches to build upon this basic information to direct stem cell differentiation into blood cell lineages. Print ISBN: 978-1-4398-7204-8 eBook ISBN: 978-1-4398-7418-9 November 2012, 7 x 10, 221 pp. Suggested Price: $119.95 / £70.99
Robotic Surgery
Supercritical Fluid Chromatography
Smart Materials, Robotic Structures, and Artificial Muscles
Advances and Applications in Pharmaceutical Analysis
Mohsen Shahinpoor and Siavash Gheshmi
Edited by
Textbook
University of Maine, Orono, USA
This text focuses on robotic surgery and biomimetic artificial muscles and their possible engineering, industrial, medical, and scientific applications. It presents the fundamentals of surgical robots, including the design of their geometrical configurations, kinematics, dynamics, and control. It also describes the designs of ophthalmic surgical robots and general laparoscopic surgical robots as well as applications of materials and systems that can be manufactured or fabricated to act like biomimetic artificial muscles, sensors, and actuators. Print ISBN: 978-981-4316-23-1 April 2014, 6 x 9, 300 pp. Suggested Price: $179.95 / £114.00
Gregory K. Webster AbbVie, Inc., North Chicago, Illinois, USA
When a drug is developed and brought to market, it is tested many times for impurities and degradants, enantiomeric purity, and analytical and preparative isolations. It is also tested during discovery and development and for under-regulated and unregulated methodologies. This book describes the use of SFC for each of these applications and discusses more in-depth topics, such as the use of SFC in mass spectrometric and polarographic detection. The book also sheds light on the role of SFC in drug development from natural products, the advancement of SFC with new technologies, and SFC’s use in pilot-scale operations as a chromatographic technique. Print ISBN: 978-981-4463-00-3 October 2013, 6 x 9, 450 pp. Suggested Price: $149.95 / £95.00
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Terahertz Biomedical Science and Technology
Systems Biology Mathematical Modeling and Model Analysis
Edited by
Andreas Kremling
This book focuses on biomedical application of terahertz (THz) waves. THz waves offer advantages because of their low energy (greater safety), long wavelength (higher resolution), and sensitivity to water molecules. It showcases the use of THz spectroscopy in elucidating biological behaviors as well as development of THz wave medical techniques such as skin drug absorption imaging and cancer diagnosis. The contents also include an overview on THz technology, encompassing generation and detection methods and imaging techniques. Overall, it provides a unique and timely summary of an important emerging field, from basic principles to state of the art applications and an outlook on the future.
Technical University Munich, Germany Series: Chapman & Hall/CRC Mathematical & Computational Biology
Drawing on the latest research in the field, this text presents many methods for modeling and analyzing biological systems, in particular cellular systems. It shows how to use predictive mathematical models to acquire and analyze knowledge about cellular systems. It also explores how the models are systematically applied in biotechnology. The book includes many analytical and numerical examples as well as exercises and a bibliography at the end of each chapter. MATLAB® code is available on the book’s CRC Press web page. Print ISBN: 978-1-4665-6789-4 November 2013, 6-1/8 x 9-1/4, 379 pp. Suggested Price: $79.95 / £49.99
Joo-Hiuk Son
Print ISBN: 978-1-4665-7044-3 June 2014, 7 x 10, 416 pp. Suggested Price: $149.95 / £95.00
Szycher’s Handbook of Polyurethanes
The Biomedical Photonics Handbook
Second Edition Edited by
Fundamentals, Devices, and Techniques, Second Edition
Michael Szycher, Ph.D
Edited by
Sterling Biomedical, Inc., Lynnfield, Massachusetts, USA
Tuan Vo-Dinh
Written as a reference for polyurethane technologists and end users, raw materials suppliers, and students in the field, this Second Edition covers the technical advances in the field over the past 10 years. Filled with tables, charts, and photographs, it includes new data on green polyurethanes, automotive applications, new coatings, new manufacturing equipment, new health-care uses, and other topics. Individuals from all major polyurethane intermediate suppliers and equipment manufacturers contributed to this updated handbook, and discuss current products and provide a comprehensive list of product portfolios.
Duke University, Durham, North Carolina, USA
Print ISBN: 978-1-4398-3958-4 eBook ISBN: 978-1-4398-6313-8 July 2012, 7 x 10, 1144 pp. Suggested Price: $210.00 / £133.00
Print ISBN: 978-1-4200-8512-9 May 2014, 7 x 10, 800 pp., Soft Cover Suggested Price: $189.95 / £121.00
Targeted Muscle Reinnervation
Tissue and Organ Regeneration
A Neural Interface for Artificial Limbs
Advances in Micro- and Nanotechnology
Edited by
Todd A. Kuiken, Aimee E. Schultz Feuser, and Ann K. Barlow
Biomedical Engineering
Textbook
Biomedical photonics is defined as the science of harnessing light and other forms of radiant energy to address problems in medicine and biology. The field has experienced explosive growth due to the noninvasive or minimally invasive nature and cost-effectiveness of photonic modalities in medical diagnostics and therapy. The Biomedical Photonics Handbook, Second Edition focuses on the fundamentals and advanced optical techniques and devices. It is an authoritative reference source for those involved in the research, teaching, learning, and practice of medical technologies.
Edited by
Series: Series in Medical Physics and Biomedical Engineering
Lijie Grace Zhang, Ali Khademhosseini, and Thomas Webster
Targeted muscle reinnervation (TMR) is a new approach to accessing motor control signals from peripheral nerves after amputation and providing sensory feedback to prosthesis users. This practical approach has many advantages over other neuralmachine interfaces for the improved control of artificial limbs. With contributions from renowned leaders in the field, including the developers of the technology, this book provides a template for the clinical implementation of TMR and a powerful resource for further research in this new area of science.
Edited by three of the top researchers in the field of tissue engineering and nanomedicine, with contributions from a team of pioneers and well-known leading experts in the biomedical field, this book presents the latest nano/microtechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. It covers and details cutting-edge research in nano/microfabrication techniques and biomaterials for various tissues/organs, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder, and cardiovascular tissue regenerations.
Print ISBN: 978-1-4398-6080-9 eBook ISBN: 978-1-4398-6081-6 July 2013, 6-1/8 x 9-1/4, 225 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-981-4411-67-7 October 2013, 6 x 9, 800 pp. Suggested Price: $169.95 / £108.00
For more information and a complete list of titles, visit us at www.crcpress.com
25
Tissue Engineering
Vascularization
Principles and Practices
Regenerative Medicine and Tissue Engineering
Edited by
John P. Fisher, Antonios G. Mikos, Joseph D. Bronzino, and Donald R. Peterson
Biomedical Engineering / Biomedical Imaging 26
With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nonobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters examine the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. It provides a very comprehensive overview of major research topics in tissue engineering.
Edited by
Eric M. Brey Illinois Institute of Technology, Chicago, USA
This book presents the latest research and science on the process of vessel assembly, with an emphasis on methods for controlling the process for therapeutic applications. It has a strong orientation toward regenerative medicine and tissue engineering applications, with contributions from engineers, basic scientists, and biologists. The book provides the reader with an understanding of the process of how blood vessels and methods for controlling this process are engineered in order to develop treatments for various pathologies and surgical situations.
Print ISBN: 978-1-4398-7400-4 eBook ISBN: 978-1-4398-7403-5 December 2012, 7 x 10, 771 pp. Suggested Price: $159.95 / £100.00
Print ISBN: 978-1-4665-8045-9 May 2014, 7 x 10, 450 pp. Suggested Price: $149.95 / £95.00
Tissue Engineering and Regenerative Medicine
Textbook
A Nano Approach
Webb’s Physics of Medical Imaging
Edited by
Second Edition
Murugan Ramalingam, ekka Vallittu, Ugo Ripamonti, and Wan-Ju Li
Edited by
This book bridges the gap between nanotechnology and regenerative medicine to facilitate the transition from lab to clinic. It compiles important aspects of basic science and fundamental principles for current nanotechnological innovations in biomaterials and cell, tissue, and organ engineering, and their clinical relevance, as well as future trends in regenerative medicine. The book is intended for a wide audience including students, researchers, professors, and industrial experts working in the fields of biomaterial science and engineering, nanoscience and nanotechnology, bioengineering, cell biology, biomedical sciences, tissue engineering, and nanomedicine.
Institute of Cancer Research/Royal Marsden NHS Foundation Trust, London, UK
Print ISBN: 978-1-4398-8185-9 eBook ISBN: 978-1-4398-8186-6 September 2012, 6-1/8 x 9-1/4, 592 pp. Suggested Price: $159.95 / £100.00
M.A. Flower Series: Series in Medical Physics and Biomedical Engineering
Since the publication of the best-selling first edition, the technology and clinical applications of medical imaging have changed significantly. Gathering these developments into one volume, this comprehensive second edition presents the basic physics, modern technology, and up-to-date examples of clinical application across all the modalities of medical imaging. It now covers state-ofthe-art detector technology and computer processing used in medical imaging. Along with many new examples and figures, this edition includes new chapters on medical image processing and multimodality imaging. Print ISBN: 978-0-7503-0573-0 eBook ISBN: 978-1-4200-1241-5 June 2012, 7 x 10, 864 pp. Suggested Price: $93.95 / £51.99
Transport Phenomena in Biomedical Engineering Principles and Practices Edited by
Robert A. Peattie, Robert J. Fisher, Joseph D. Bronzino, and Donald R. Peterson This book couples the concepts of transport phenomena with chemical reaction kinetics and thermodynamics to introduce the field of reaction engineering. This is essential information needed to design and control engineering devices, particularly flow reactor systems. Each chapter is somewhat self-contained. Similar concepts are brought forth and reinforced through applications and discussions. However, to further enhance the benefits obtained by the reader, the book first examines some elementary concepts, the most relevant being control volume selection and flow reactors. It then provides a comprehensive treatment with an overview of major research topics related to transport phenomena pertaining to biomedical engineering. Print ISBN: 978-1-4398-7462-2 eBook ISBN: 978-1-4398-7463-9 November 2012, 7 x 10, 197 pp. Suggested Price: $129.95 / £80.00
Adaptive Optics for Biological Imaging Edited by
Joel A. Kubby University of California-Santa Cruz, USA
Written by international leaders in the field, this comprehensive reference presents a complete overview of the core principles, state-of-the-art methods, and emerging applications of adaptive optics in biological imaging. It emphasizes the use of adaptive optics to correct wavefront aberrations caused by light propagation in biological samples. Accessible to readers without a background in optics, the book describes the fundamentals, components, and systems used in adaptive optics. It also covers optics systems as well as newer applications in this rapidly expanding field. Print ISBN: 978-1-4398-5018-3 eBook ISBN: 978-1-4398-5019-0 April 2013, 7 x 10, 388 pp. Suggested Price: $99.95 / £63.99
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Advanced Biophotonics
Textbook
Edited by
Biomedical Signal and Image Processing
Ruikang K. Wang
Second Edition
Tissue Optical Sectioning University of Washington, Seattle, USA
Kayvan Najarian
Valery V. Tuchin
Virginia Commonwealth University, Richmond, USA
Saratov State University, Russia
Robert Splinter
Series: Series in Optics and Optoelectronics
Print ISBN: 978-1-4398-9581-8 eBook ISBN: 978-1-4398-9582-5 July 2013, 7 x 10, 733 pp. Suggested Price: $199.95 / £127.00
Written for senior-level and first-year graduate students in biomedical signal and image processing, this book describes fundamental signal and image processing techniques that are used to process biomedical information. The book also discusses application of these techniques in the processing of some of the main biomedical signals and images, such as EEG, ECG, MRI, and CT. New features of this edition include the technical updating of each chapter along with the addition of many more examples, the majority of which are MATLAB® based. Print ISBN: 978-1-4398-7033-4 eBook ISBN: 978-1-4665-0655-8 May 2012, 6-1/8 x 9-1/4, 411 pp. Suggested Price: $119.95 / £70.99
Textbook
Textbook
Applied Medical Image Processing
Biosignal and Medical Image Processing
A Basic Course, Second Edition
Third Edition
Wolfgang Birkfellner
John L. Semmlow
Medical University of Vienna, Austria
With data sets and MATLAB on an accompanying CDROM, the second edition of this bestseller gives more attention to the subject of color space and includes more examples from radiology, internal medicine, surgery, and radiation therapy. The book addresses problems with handling voxels, 3D data sets, spatial transforms in three dimensions, and data fusion. It shows how to visualize large data sets from modern CT systems, manufacture patient-specific prostheses, plan dose distributions, incorporate multimodal image data for therapy monitoring, and perform computer-aided neurosurgical interventions. ®
Print ISBN: 978-1-4665-5557-0 January 2014, 7 x 10, 454 pp. Suggested Price: $79.95 / £49.99
Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
This third edition of a bestseller offers comprehensive coverage of the major approaches in biomedical signal and image processing. It provides a complete set of signal processing tools, including diagnostic decisionmaking tools, and classification methods. Thoroughly revised and updated, it supplies important new material on nonlinear methods for describing and classifying signals, including entropy-based methods and scaling methods. This edition covers data “cleaning” methods commonly used in such areas as heart rate variability studies, along with actual examples. It also includes new end-ofchapter problems. Print ISBN: 978-1-4665-6736-8 January 2014, 7 x 10, 620 pp. Suggested Price: $119.95 / £76.99
Artificial Human Sensors Edited by
Clinical Application of Computer-Guided Implant Surgery
Peter Wide
Andreas Parashis
Science and Applications Orebro University, Sweden
Biomedical Imaging
University of North Carolina at Charlotte, USA
Despite a number of books on biophotonics imaging for medical diagnostics and therapy, the field still lacks a comprehensive imaging book that describes state-of-the-art biophotonics imaging approaches intensively developed in recent years. Addressing this shortfall, Advanced Biophotonics presents contemporary methods and applications of biophotonics imaging. Gathering research otherwise scattered in numerous physical, chemical, biophysical, and biomedical journals, the book helps researchers, bioengineers, and medical doctors understand major recent bioimaging technologies and the underlying biophotonics science.
Tufts University, Boston, Massachusetts, USA
As the elderly population increases, the importance of creating sophisticated information support to humans with limited sensing performance has also grown. This book discusses human and artificial sensing in conjunction with human perception capabilities (auditory, taste, smell, vision, and touch). It also discusses the fusion of this sensing information to find answers to questions such as how we can increase our human “fuzzy” decision capability (perception). The book presents intelligent new technologies that can enhance the natural sensing, perception, and mobility abilities of humans, allowing them to have healthier, more productive, and safer lives.
Panagiotis Diamantopoulos
Print ISBN: 978-981-4241-58-8 eBook ISBN: 978-981-4267-64-9 March 2012, 6 x 9, 220 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4822-0541-1 eBook ISBN: 978-1-4822-0542-8 September 2013, 8-1/2 x 11, 176 pp. Suggested Price: $179.95 / £114.00
University of Sussex, UK
Enhanced with color photos, this book covers the practical application of computer-guided implants (CGIP) in a simple but detailed manner. Using actual images from clinical cases, it helps readers understand the treatment pathway, radiographic guides, virtual teeth, imaging techniques, and computer software used for CGIP. Step by step, it explores diagnosis and treatment planning, applying the specialized software, and using the necessary instruments and surgical guides. It also explores the strengths and weaknesses of CGIP and discusses literature related to its accuracy and clinical relevance.
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Coherent Raman Scattering Microscopy
Correction Techniques in Emission Tomography
Edited by
Edited by
Ji-Xin Cheng Purdue University, West Lafayette, Indiana, USA
Mohammad Dawood, Xiaoyi Jiang, and Klaus Schäfers
Xiaoliang Sunney Xie
Series: Series in Medical Physics and Biomedical Engineering
Harvard University, Cambridge, Massachusetts, USA Series: Series in Cellular and Clinical Imaging
Biomedical Imaging
Edited by pioneers in the field and with contributions from a distinguished team of experts, this full-color book explains how CRS can be used to obtain a point-by-point chemical map of live cells and tissues. It discusses the principles of nonlinear optical spectroscopy and presents the theories of contrast mechanisms pertinent to CRS microscopy. The text provides important technical aspects of CRS microscopy, including microscope construction, detection schemes, and data analyses. It also covers applications that demonstrate how CRS microscopy has become a valuable tool in biomedicine. Print ISBN: 978-1-4398-6765-5 eBook ISBN: 978-1-4398-6766-2 October 2012, 7 x 10, 610 pp. Suggested Price: $159.95 / £100.00
Comprehensive Brachytherapy
Print ISBN: 978-1-4398-1298-3 eBook ISBN: 978-1-4398-1301-0 April 2012, 6-1/8 x 9-1/4, 287 pp. Suggested Price: $125.95 / £81.00
Physical and Clinical Aspects
Emerging Imaging Technologies in Medicine
Edited by
Edited by
Jack Venselaar, Ali S. Meigooni, Dimos Baltas, and Peter J. Hoskin
Mark A. Anastasio
Brachytherapy delivers a highly localized dose to a target region using radionuclides implanted in or very near to the tumor. This book provides a complete overview of the field and covers related delivery modalities such as electronic brachytherapy. Along with exploring new clinical protocols, it discusses major advances under development, including imaging and robotics, and strategies for improved dosimetry, Monte Carlo-based dose calculation, and optimization. The first part of the text offers a detailed understanding of the underlying physics, design, and implementation of the techniques. The second part provides a practical guide for practitioners.
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Written by an interdisciplinary team of medical doctors, computer scientists, physicists, engineers, and mathematicians, this volume presents various correction methods used in emission tomography to generate and enhance images. Topics include nuclear medicine imaging, hybrid emission tomography, and optical imaging. An important aspect of the book is the exploration of new and sophisticated motion correction techniques in PET imaging. The contributors illustrate basic principles as well as recent advances, such as model-based iterative algorithms and 4D methods.
Print ISBN: 978-1-4398-4498-4 eBook ISBN: 978-1-4398-4499-1 November 2012, 8-1/2 x 11, 535 pp. Suggested Price: $210.00 / £133.00
Washington University, St. Louis, Missouri, USA
Patrick La Riviere University of Chicago, Illinois, USA
This book offers a comprehensive survey of emerging medical imaging technologies that show great promise for routine clinical use. Each chapter provides a detailed discussion of the physics/technology and addresses improvements in terms of dose, sensitivity, and/or specificity, which are limitations of current imaging approaches. The book reflects the major advances in computer hardware, nanofabrication, and laser technology that have led to developments in phase-contrast imaging, photoacoustic imaging, and optical imaging. It covers multimodality imaging, including PET/MRI, as well as three-dimensional microscopy. Print ISBN: 978-1-4398-8041-8 eBook ISBN: 978-1-4398-8042-5 December 2012, 8-1/2 x 11, 361 pp. Suggested Price: $179.95 / £113.00
Cone Beam Computed Tomography
The Fluorescent Protein Revolution
Edited by
Edited by
Chris C. Shaw
Richard N. Day
The University of Texas M.D. Anderson Cancer Center, Houston, USA
Indiana University, Indianapolis, USA
This volume shows how cone beam computed tomography (CT) is used to provide highly customized radiation treatment with less radiation exposure, fewer side effects, higher doses to the tumor, and lower doses to normal structures. The book focuses on image acquisition, reconstruction, and processing/display, along with issues surrounding image quality, artifacts, radiation dose, and perception. Each application-oriented chapter describes implementation and special characteristics of the system used. The book also examines the latest research developments, the fundamental limitations of the technology, and future advances.
Florida State University, Tallahassee, USA
Print ISBN: 978-1-4398-4626-1 January 2014, 8-1/2 x 11, 284 pp. Suggested Price: $179.95 / £114.00
Michael W. Davidson Series: Series in Cellular and Clinical Imaging
This reference discusses major advances in the development of novel imaging techniques that exploit new probes. It describes the photophysical properties of new fluorescent probes, particularly the important red fluorescent probes from corals. The book gives a detailed account of stateof-the-art imaging methods that exploit the characteristics of new probes. It also illustrates the applications of fluorescent probes in a variety of optical techniques, including superresolution microscopy. Many figures throughout the text further clarify concepts. Print ISBN: 978-1-4398-7508-7 May 2014, 6-1/8 x 9-1/4, 280 pp. Suggested Price: $129.95 / £82.00
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Image Analysis and Modeling in Ophthalmology
Edited by
Edited by
Corey Neu Guy Genin
E. Y. K. Ng, U. Rajendra Acharya, Jasjit S. Suri, and Aurelio Campilho
This encyclopedic handbook covers the entire spectrum of imaging techniques used in biomechanics, from the macroscopic to the sub-microscopic. It presents optimal imaging technologies to study deformation, stress, and constitutive behavior of proteins, cells, and tissues. It also addresses challenges in bridging across multiple length scales. The book discusses imaging morphology—how small can we go in vivo and in vitro—and explores beyond morphology, including coupling or extending imaging technology with biological and functional (mechanical) information.
Successful thermal modeling of the human eye helps in the early diagnosis of eye abnormalities such as inflammation, cataracts, diabetic retinopathy, and glaucoma—all leading causes of blindness. This book presents a unified work of eye imaging and modeling techniques that have been proposed and applied to ophthalmologic problems. It delves into various morphological, texture, higher order spectra, and wavelet transformation techniques used to extract important diagnostic features from images, which can then be analyzed by a data scientist for automated diagnosis.
Print ISBN: 978-1-4665-8813-4 May 2014, 8-1/2 x 11, 1000 pp. Suggested Price: $199.95 / £127.00
Print ISBN: 978-1-4665-5930-1 January 2014, 7 x 10, 412 pp. Suggested Price: $199.95 / £127.00
Handbook of Photomedicine
Image Processing
Edited by
Tensor Transform and Discrete Tomography with MATLAB®
Michael R. Hamblin and Ying-Ying Huang Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, USA
Providing the most comprehensive, up-to-date coverage of this exciting biomedical field, this handbook gathers together a large team of international experts to give readers a complete account of the application of light in healthcare and medical science. The book progresses logically from the history and fundamentals of photomedicine to diverse therapeutic applications of light, known collectively as phototherapies. It facilitates understanding of human diseases caused by light, the rationale for photoprotection, and major applications of phototherapy in clinical practice. Print ISBN: 978-1-4398-8469-0 eBook ISBN: 978-1-4398-8470-6 October 2013, 8-1/2 x 11, 886 pp. Suggested Price: $199.95 / £127.00
Artyom M. Grigoryan San Antonio, Texas, USA
Merughan M. Grigoryan Yerevan, Armenia
Focusing on mathematical methods in computer tomography, this book introduces novel approaches to help solve the problem of image reconstruction on the Cartesian lattice. Specifically, it discusses methods of image processing along parallel rays to more accurately reconstruct images from a finite number of projections and avoid overradiating the body during a CT scan. The book presents several new concepts and methods, including methods of transferring the geometry of rays from the plane to the Cartesian lattice, the point map of projections, the particle and its field function, and the statistical model of averaging. Print ISBN: 978-1-4665-0994-8 eBook ISBN: 978-1-4665-0995-5 October 2012, 6-1/8 x 9-1/4, 466 pp. Suggested Price: $159.95 / £100.00
Human Eye Imaging and Modeling
Image Processing and Acquisition using Python
Edited by
Ravishankar Chityala
E. Y. K. Ng, Jen Hong Tan, U. Rajendra Acharya, and Jasjit S. Suri
University of Minnesota, Minneapolis, USA
Advanced image processing and mathematical modeling techniques are increasingly being used for the early diagnosis of eye diseases. This comprehensive reference details the latest advances and computer-based techniques in imaging and modeling of the human eye. Featuring contributions by wellknown experts in the field, it covers imaging of fundus and infrared images, diagnosis of diabetes retinopathy and glaucoma, estimation of tear evaporation of dry eye, computer simulation of the human eye based on principles of heat transfer, various bioheat equations to predict interior temperatures based on the surface temperatures, and more. Print ISBN: 978-1-4398-6993-2 eBook ISBN: 978-1-4665-6620-0 June 2012, 6-1/8 x 9-1/4, 430 pp. Suggested Price: $199.95 / £127.00
Biomedical Imaging
Handbook of Imaging in Biological Mechanics
Sridevi Pudipeddi SriRav Scientific Solutions, Minneapolis, Minnesota, USA Series: Chapman & Hall/CRC Mathematical and Computational Imaging Sciences Series
The book is designed for upper-level under-graduates, graduate students, and researchers in various STEM disciplines interested in performing efficient and cost-effective image acquisition and processing. The concepts of image processing are presented with examples written using Python, long recognized as one of the easiest languages for non-programmers to learn. The book is supplemented with a Python module to perform these image processing operations. Print ISBN: 978-1-4665-8375-7 January 2014, 6-1/8 x 9-1/4, 392 pp. Suggested Price: $79.95 / £49.99
For more information and a complete list of titles, visit us at www.crcpress.com
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Biomedical Imaging
Image Processing in Radiation Therapy
Introduction to Medical Imaging Management
Edited by
Bernard Rubenzer
Kristy K. Brock
Waukesha, Wisconsin, USA
University of Michigan, Ann Arbor, USA
This comprehensive book provides an in-depth overview of all the basics pertaining to the knowledge and skills necessary to become a department or imaging center supervisor or manager. The text follows a natural progression from transitioning into a management position and dealing with former peers through the most sophisticated skills uniquely applicable to medical imaging management. Covering all aspects of the profession—operations, human resources, finance, and marketing—this reference is a must-have for any potential, new, or less experienced imaging manager.
Images from CT, MRI, PET, and other medical instrumentation have become central to the radiotherapy process in the past two decades, thus requiring medical physicists, clinicians, dosimetrists, radiation therapists, and trainees to integrate and segment these images efficiently and accurately in a clinical environment. This book presents an upto-date, detailed treatment of techniques and algorithms for the registration, segmentation, reconstruction, and evaluation of imaging data. It describes how these tools are used in radiation planning, treatment delivery, and outcomes assessment. Print ISBN: 978-1-4398-3017-8 eBook ISBN: 978-1-4398-3018-5 August 2013, 8-1/2 x 11, 286 pp. Suggested Price: $129.95 / £82.00
Imaging for Plastic Surgery
Knowledge-Driven Medicine
Edited by
A Machine Learning Approach
Luca Saba, Warren Rozen, Alberto A. Burgos, and Diego Ribuffo Preoperative imaging is increasingly being adopted for preoperative planning in plastic surgery. Accurate preoperative analysis can reduce the length of operations and maximize surgical design and dissection technique. This book comprehensively covers the techniques, potentialities, and present and future applications of medical imaging technology as applied to plastic and reconstructive surgery, with the most world-renowned scientists in this field. The book comprises four main sections, covering imaging principles; face, head, and neck; breast; extremities and trunk; and others. The editors and contributors are world-class experts in plastic surgery imaging.
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Print ISBN: 978-1-4398-9183-4 eBook ISBN: 978-1-4398-9184-1 January 2013, 6-1/8 x 9-1/4, 200 pp. Suggested Price: $89.95 / £57.99
Print ISBN: 978-1-4665-5111-4 January 2014, 7 x 10, 500 pp. Suggested Price: $189.95 / £108.00
Edited by
R. Bharat Rao, Glenn Fung, and Romer Rosales Series: Chapman & Hall/CRC Data Mining and Knowledge Discovery Series
Focusing on recent, novel machine learning automatic algorithms, this reference provides the first source on the use of machine learning methods in designing computeraided diagnosis (CAD) systems. It proposes a framework for CAD problems, presents the technical issues involved when building classifiers, and provides the appropriate machine learning techniques to address these problems. The book also includes results and concrete examples for different diseases and imaging modalities. It provides a useful tool for researchers and students in the biomedical sciences and machine learning as well as for advanced courses on CAD and/or medical informatics. Print ISBN: 978-1-4398-3887-7 June 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $89.95 / £54.99
Imaging in Cellular and Tissue Engineering
Textbook
Edited by
The Basics
Hanry Yu
Christakis Constantinides
National University of Singapore
Nur Aida Abdul Rahim National University of Singapore Series: Series in Cellular and Clinical Imaging
As the field of tissue engineering moves from creating simple outer body parts to more sophisticated internal organs, researchers need to evaluate and control how well the tissues are engineered and integrated into the living body. Suitable for both experts and newcomers in bioengineering and biomedical imaging, this book shows researchers how to apply imaging techniques to next-generation engineered cells and tissues. It helps them assess the suitability of specific imaging modalities for applications with various functional requirements. Print ISBN: 978-1-4398-4803-6 eBook ISBN: 978-1-4398-4804-3 May 2013, 7 x 10, 298 pp. Suggested Price: $149.95 / £95.00
Magnetic Resonance Imaging University of Cyprus, Nicosia
Magnetic Resonance Imaging (MRI) is one of the most powerful diagnostic techniques available, detecting everything from a torn meniscus to cancer. An MRI teaching primer, this text addresses the basic principles at a level suitable for undergraduate and graduate students. Developed from the author’s courses at Johns Hopkins University and the University of Cyprus, the book illustrates physical principles using a series of diagrams and includes homework exercises, case studies, and questions. An ideal textbook, it can also be used by researchers in labs, diagnostic centers, and hospitals with MRI. Print ISBN: 978-1-4822-1731-5 March 2014, 7 x 10, 208 pp., Soft Cover Suggested Price: $69.95 / £44.99
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Medical Imaging
Metalloproteins
Principles and Practices
Structure, Functions, and Interactions
Edited by
Edited by
Mostafa Analoui, Joseph D. Bronzino, and Donald R. Peterson
Art E. Cho, Korea University, Korea, and William A. Goddard III
Print ISBN: 978-1-4398-7102-7 eBook ISBN: 978-1-4398-7103-4 November 2012, 7 x 10, 454 pp. Suggested Price: $119.95 / £70.99
California Institute of Technology, Pasadena, USA
Metal ions in metalloproteins are critical to the protein’s function, structure, and stability. Because numerous essential biological functions require metal ions and most of these functions involve metalloproteins, understanding metalloproteins and how to manipulate them is of great importance in the biological and medical fields. This book examines current research on metalloproteins and the interplay between theory and experiment, detailing the role of theoretical modeling in the field and explaining how it aids experiments. The text also presents the current state of computational protein modeling, enabling researchers to adopt computation as an integral component of their studies. Print ISBN: 978-1-4398-1318-8 June 2014, 6-1/8 x 9-1/4, 240 pp. Suggested Price: $129.95 / £82.00
Medical Imaging Technology and Applications
Microarray Image and Data Analysis
Edited by
Theory and Practice
Troy Farncombe
Edited by
McMaster University, Hamilton, Ontario, Canada
Kris Iniewski CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada Series: Devices, Circuits, and Systems
The book has two intentions. First, it assembles the latest research in the field of medical imaging technology in one place. Detailed descriptions of current stateof-the-art medical imaging systems (comprised of x-ray CT, MRI, ultrasound, and nuclear medicine) and data processing techniques are discussed. Information is provided that will give interested engineers and scientists a solid foundation from which to build with additional resources. Secondly, it exposes the reader to myriad applications that medical imaging technology has enabled.
Luis Rueda Series: Digital Imaging and Computer Vision, 8
This book provides an overview of microarray image analysis, covering different types of microarrays such as cDNA, protein, tissue, and low and high-density oligonucleotide arrays. Broad in scope, the book covers the most important aspects of microarray image analysis, including gridding, segmentation, quantification, normalization, clustering, and network analysis. Print ISBN: 978-1-4665-8682-6 March 2014, 6-1/8 x 9-1/4, 488 pp. Suggested Price: $99.95 / £63.99
Print ISBN: 978-1-4665-8262-0 eBook ISBN: 978-1-4665-8263-7 October 2013, 6-1/8 x 9-1/4, 732 pp. Suggested Price: $149.95 / £95.00
Medical Infrared Imaging Principles and Practices Edited by
Mary Diakides, Joseph D. Bronzino, and Donald R. Peterson This book explores new ideas, concepts, and technologies such as dynamic thermal imaging, thermal texture mapping, and thermal multispectral imaging commonly used in the clinical environment. The coverage ranges from historical background, concepts, clinical applications, standards, and infrared technology. Of interest to the medical and biomedical engineering communities, the book can provide many opportunities for developing and conducting multidisciplinary research in many areas of medical infrared imaging. Print ISBN: 978-1-4398-7249-9 eBook ISBN: 978-1-4398-7250-5 December 2012, 7 x 10, 638 pp. Suggested Price: $129.95 / £75.99
Biomedical Imaging
This book offers a selective review of key imaging modalities focusing on modalities with established clinical utilization. It provides a detailed overview of x-ray imaging and computed tomography, fundamental concepts in signal acquisition and processes, followed by an overview of functional MRI (fMRI) and chemical shift imaging. It also covers topics in Magnetic Resonance Microscopy (MRM), the physics of instrumentation and signal collection, and their application in clinical practice. The selection of topics provides readers with an appreciation of the depth and breadth of the field and the challenges ahead of the technical and clinical community of researchers and practitioners.
31 Monte Carlo Calculations in Nuclear Medicine Second Edition Applications in Diagnostic Imaging Edited by
Michael Ljungberg, Sven-Erik Strand, and Michael A. King Series: Series in Medical Physics and Biomedical Engineering
From first principles to current computer applications, this book covers the applications of Monte Carlo calculations in nuclear medicine and critically reviews them from a diagnostic perspective. New chapters in this edition cover codes and applications in pre-clinical PET and SPECT. The book explains how Monte Carlo methods and software packages can be applied to evaluate scatter in SPECT and PET imaging, collimation, and image deterioration. A guide for researchers developing methods to improve image resolution, it also demonstrates how Monte Carlo techniques can be used to simulate complex imaging systems. Print ISBN: 978-1-4398-4109-9 eBook ISBN: 978-1-4398-4110-5 November 2012, 6-1/8 x 9-1/4, 357 pp. Suggested Price: $135.95 / £86.00
For more information and a complete list of titles, visit us at www.crcpress.com
Multi-Detector CT Imaging Handbook
MRI
Two Volume Set
Essentials for Innovative Technologies
Edited by
Giuseppe Placidi University of L’Aquila, Italy
Luca Saba University of Cagliari, Italy
Jasjit S. Suri Global Biomedical Technologies, Inc., Roseville, California, USA
Biomedical Imaging
This book covers the engineering and clinical benefits in diagnosis of human pathologies, including the protocols and potential of advanced tomography scanning with very high quality CT images. With contributions from world-class experts, the book examines all aspects of CT technologies related to the neck and brain, the cardiovascular system, the thorax, the abdomen and GI system, the pelvis and urinary system, and the musculoskeletal system. It also provides coverage of CAD applications to CT along with a discussion of the potential dangers of CT in terms of over-radiation, particularly related to children. Print ISBN: 978-1-4398-9399-9 November 2013, 8-1/2 x 11, 1272 pp. Suggested Price: $279.95 / £178.00
Also available as individual volumes
Multi-Detector CT Imaging Abdomen, Pelvis, and CAD Applications Print ISBN: 978-1-4398-9397-5 eBook ISBN: 978-1-4398-9398-2 November 2013, 8-1/2 x 11, 689 pp. Suggested Price: $179.95 / £114.00
Multi-Detector CT Imaging Principles, Head, Neck, and Vascular Systems Print ISBN: 978-1-4398-9380-7 eBook ISBN: 978-1-4398-9384-5 November 2013, 8-1/2 x 11, 583 pp. Suggested Price: $179.95 / £114.00
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This book describes innovative methods to improve magnetic resonance imaging (MRI) beyond its current limitations. The author proposes smart encoding methods and acquisition sequences to deal with frequency displacement due to residual static magnetic field inhomogeneity, motion, and undersampling. After a concise review of basic mathematical tools and the physics of MRI, the book describes each limitation and then proposes solutions for overcoming it. Requiring few or no hardware modifications, these speculative methods represent building blocks for more advanced MRI applications. The book also looks to the future of MRI. Print ISBN: 978-1-4398-4040-5 eBook ISBN: 978-1-4398-4062-7 May 2012, 6-1/8 x 9-1/4, 216 pp. Suggested Price: $109.95 / £51.99
Ophthalmology Imaging and Applications Edited by
E. Y. K. Ng, U. Rajendra Acharya, Rangaraj M. Rangayyan, and Jasjit S. Suri Emphasizing the latest methods and techniques, this book covers all aspects of multi-model ophthalmology imaging and applications. Edited by and featuring contributions by world-class researchers in the field, this book offers a unified work of eye imaging and modeling techniques that have been proposed and applied to ophthalmologic problems. The book focuses on theory, basic principles, and results derived from research and presented them in an accessible manner to appeal to a wide audience of eyecare professionals and researchers. This volume is intended as a companion to Image Analysis and Modeling in Ophthalmology. Print ISBN: 978-1-4665-5913-4 May 2014, 7 x 10, 504 pp. Suggested Price: $199.95 / £127.00
Monte Carlo Techniques in Radiation Therapy
Optical Imaging Techniques in Cell Biology
Edited by
Second Edition
Joao Seco Massachusetts General Hospital, Boston, USA
Frank Verhaegen Maastro Clinic, Maastricht, Netherlands
This book explores the use of Monte Carlo methods for modeling various features of internal and external radiation sources. It addresses applications of the Monte Carlo particle transport simulation technique in radiation therapy, mainly focusing on external beam radiotherapy and brachytherapy. Along with presenting mathematical and technical aspects of the methods, the book discusses the modeling of medical linacs and other irradiation devices; issues specific to electron, photon, and proton ion beams and brachytherapy; and the optimization of treatment planning, radiation dosimetry, and quality assurance. Print ISBN: 978-1-4665-0792-0 eBook ISBN: 978-1-4665-0794-4 March 2013, 8-1/2 x 11, 342 pp. Suggested Price: $149.95 / £95.00
Guy Cox University of Sydney, New South Wales, Australia
This reference on optical imaging techniques covers the field from the basics of the optical microscope to highly advanced techniques such as Förster resonant energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM). Using a uniform style and format, it provides an understanding of the underlying principles, so readers can learn the benefits and limitations of each technique described. Topics covered include: optical contrasting techniques, fluorescence and fluorescence microscopes, three-dimensional imaging, the confocal microscope, nonlinear microscopy, advanced fluorescence techniques, and breaking the diffraction limit. Chapters include suggestions for further reading. Print ISBN: 978-1-4398-4825-8 eBook ISBN: 978-1-4398-4828-9 June 2012, 6-1/8 x 9-1/4, 316 pp. Suggested Price: $159.95 / £100.00
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Optical Nanoscopy and Novel Microscopy Techniques
Quantifying Morphology and Physiology of the Human Body Using MRI
Edited by
Edited by
Peng Xi
L. Tugan Muftuler
Peking University Hospital, Beijing, China
Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, USA
Print ISBN: 978-1-4665-8629-1 May 2014, 6-1/8 x 9-1/4, 500 pp. Suggested Price: $149.95 / £95.00
Series: Series in Medical Physics and Biomedical Engineering
This book is an indispensable reference for readers who would like to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms. It presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems. With internationally renowned experts sharing their insight on the latest developments, the book goes beyond conventional MRI contrast mechanisms to include new techniques that measure electromagnetic and mechanical properties of tissues. Print ISBN: 978-1-4398-5265-1 eBook ISBN: 978-1-4398-5268-2 May 2013, 6-1/8 x 9-1/4, 525 pp. Suggested Price: $169.95 / £108.00
Optical, Acoustic, Magnetic, and Mechanical Sensor Technologies
Second Harmonic Generation Imaging
Edited by
Edited by
Krzysztof Iniewski
Francesco S. Pavone
CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada
Universita degli Studi di Firenze, Sesto Fiorentino, Italy
Series: Devices, Circuits, and Systems
University of Wisconsin-Madison, USA
Biomedical Imaging
Many new methods in light and super-resolution microscopy have been developed over the last few years. This edited volume overviews the latest advances in microscopy, complete with experimental methods and data analysis of the results.
Paul J. Campagnola
Although there have been extensive developments in computing and communications needs of integrated microsystems, the sensors required to conduct advanced and integrated tasks are only now seeing transformational change. With their huge potential interfacing applications for biological and medical fields, sensors will soon become ubiquitous. Focusing heavily on practical applications but remaining light on physics and math, this book addresses the developments necessary to make truly integrated sensors a reality in physical, biological, optical, and chemical sensing, as well as future micro- and nanotechnologies.
Series: Series in Cellular and Clinical Imaging
Print ISBN: 978-1-4398-6975-8 eBook ISBN: 978-1-4398-6978-9 January 2012, 6-1/8 x 9-1/4, 357 pp. Suggested Price: $159.95 / £100.00
Print ISBN: 978-1-4398-4914-9 eBook ISBN: 978-1-4398-4915-6 June 2013, 7 x 10, 476 pp. Suggested Price: $149.95 / £95.00
Physics of Mammographic Imaging
Surface Imaging for Biomedical Applications
Edited by
Edited by
Mia K. Markey
Ahmad Fadzil Mohamad Hani
The University of Texas at Austin, USA
Universiti Teknologi Petronas, Perak, Malaysia
A comprehensive treatment of developments in this field, this book covers the fundamentals of image formation, image interpretation, analysis, and modeling. It includes coverage of the use of mammographic imaging in the detection, diagnosis, treatment planning, and monitoring of breast cancer. Expert authors give a balanced summary of core topics such as digital mammography, contrast-enhanced mammography, stereomammography, breast tomosynthesis, and breast CT. The book highlights the use of mammographic imaging with complementary breast imaging modalities such as ultrasound, MRI, and nuclear medicine techniques. It discusses critical issues such as computer-aided diagnosis, perception, and quality assurance.
A range of medical imaging devices can be used to diagnose skin abnormalities and related diseases as well as for interventional and non-invasive procedures. This book focuses on the various aspects of medical imaging devices and techniques including processing and pattern recognition. The book is structured in a reader-friendly fashion, with chapters designed according to the various measurement parameters related to surface imaging such as skin coloring, thickness, roughness, and body surface.
Second-harmonic generation (SHG) serves as the basis for a microscope imaging contrast mechanism that visualizes cell and tissue structure and function. This book gives a complete overview of the principles underlying this technique and its current applications, including use in molecular sensing. Covering practical issues related to instrumentation and methods, the text offers detailed reviews of the capabilities and use of SHG in biomedical research, from imaging of cancer and skin disorders to self-assembled gels, holographic SHG imaging, and tissue engineering applications.
Print ISBN: 978-1-4822-1578-6 March 2014, 6-1/8 x 9-1/4, 312 pp. Suggested Price: $159.95 / £99.00
Print ISBN: 978-1-4398-7544-5 eBook ISBN: 978-1-4398-7546-9 November 2012, 8-1/2 x 11, 317 pp. Suggested Price: $189.95 / £120.00
For more information and a complete list of titles, visit us at www.crcpress.com
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Targeted Molecular Imaging Edited by
Michael J. Welch Washington University, Saint Louis, Missouri, USA
William C. Eckelman University of California, San Diego, La Jolla, USA
Biomedical Imaging / Biotechnology 34
This work is a comprehensive account of state-ofthe-art disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery. The book includes examples from human studies with discussions related to imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases. The book is a valuable tool for readers involved with targeted molecular imaging, medicinal chemistry, pharmacology, radiology, and medical physics. Print ISBN: 978-1-4398-4195-2 eBook ISBN: 978-1-4398-4196-9 February 2012, 8-1/2 x 11, 388 pp. Suggested Price: $179.95 / £113.00
Tomosynthesis Imaging Edited by
Ingrid Reiser The University of Chicago, Illinois, USA
Stephen Glick The University of Massachusetts, Worcester, USA
This cutting-edge book presents a comprehensive overview of tomosynthesis, a new three-dimensional x-ray imaging technique that provides improved visualization of complex anatomic structures over conventional radiography as well as CT and MR imaging. The text covers technical aspects and clinical applications and offers detailed discussions of system design and image reconstruction strategies. It provides readers with an in-depth understanding of the process of image formation and the practical tools necessary to tailor their tomosynthesis systems for new clinical applications.
Applications of Microbial Engineering Edited by
Vijai Kumar Gupta, Monika Schmoll, Minna Maki, Maria Tuohy, and Marcio Antonio Mazutti Applications of Microbial Engineering provides a better understanding of industrially important genetically manipulated and engineered prokaryotic and eukaryotic cell systems. The content of this book are based on the most recent developments in microbial engineering. The contributions by specialists on the respective topics provide a profound scientific basis for further research. This book is a valuable resource for researchers as well as students dealing with microbiology and biotechnology. Print ISBN: 978-1-4665-8577-5 eBook ISBN: 978-1-4665-8578-2 June 2013, 6-1/8 x 9-1/4, 504 pp. Suggested Price: $179.95 / £114.00
Biomass Processing Technologies Vladimir Strezov Macquarie University, Sydney, Australia
This book is a thoroughly up-to-date treatment of all the available technologies for biomass conversion. Each chapter looks at the viability and implementation of each technology with examples of existing equipment and plants. Additionally, a chapter on the economics of biomass processing is included. The book could be used as a supplementary text for senior undergraduate courses on biomass processing. Print ISBN: 978-1-4665-6616-3 June 2014, 6-1/8 x 9-1/4, 525 pp. Suggested Price: $99.95 / £63.99
Print ISBN: 978-1-4398-7870-5 February 2014, 8-1/2 x 11, 259 pp. Suggested Price: $169.95 / £108.00
Vibrational Spectroscopy for Tissue Analysis
Biosurfactants
Ihtesham ur Rehman, Zanyar Movasaghi, and Shazza Rehman
Edited by
Series: Series in Medical Physics and Biomedical Engineering
This book presents a variety of vibrational spectroscopic techniques, focusing on Raman and Fourier transform infrared (FTIR) spectroscopy and their use in noninvasive optical tissue diagnosis. It covers the most recent research in this area to create a unique database of different chemical bands and their assignments of spectral bands. The text explores the spectroscopic investigation of different tissues and samples, including breast tissue, lung tissue, and brain tissue. Based on their years of experience with various applications, the authors provide definitions of peak frequencies as well as other aspects of spectroscopy that could be helpful to a wide range of scientists. Print ISBN: 978-1-4398-3608-8 eBook ISBN: 978-1-4398-3609-5 September 2012, 6-1/8 x 9-1/4, 356 pp. Suggested Price: $169.95 / £104.00
Research Trends and Applications Catherine N. Mulligan, Ackmez Mudhoo, and Sanjay K. Sharma Institute of Engineering and Technology, Rajasthan, India
Biosurfactants have the properties of reducing surface tension, stabilizing emulsions, and promoting foaming, and are generally non-toxic and biodegradable. Interest in microbial surfactants has been steadily increasing in recent years due to their diversity, environmentally friendly nature, possibility of large-scale production, selectivity, performance under extreme conditions, and potential applications in environmental protection. This book provides an up-to-date, coherently written, and objectively presented set of book chapters from eminent international researchers who are actively involved in academic and technological research in the area of biosurfactants. Print ISBN: 978-1-4665-1823-0 January 2014, 6-1/8 x 9-1/4, 362 pp. Suggested Price: $159.95 / £95.00
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Biotechnological Applications of Microalgae
Biotechnology of Fungal Genes
Biodiesel and Value-Added Products
Edited by
Edited by
V. K. Gupta and M. Ayyachamy National University of Ireland, Galway
Durban University of Technology, South Africa
This book presents the latest developments and recent research trends focusing on potential biotechnological applications of microalgae. It gives an analysis of microalgal biology, ecology, biotechnology, and biofuel production capacity as well as a thorough discussion on the value-added products that can be generated from diverse microalgae. Chapters cover strain selection, growth characteristics, large-scale culturing, enumeration methods, and biomass harvesting and dewatering techniques. They also describe extraction, identification, and transesterification of microalgal lipids, and microalgae involvement in CO2 sequestration and phycoremediation.
This volume focuses on filamentous fungi and highlights the advances of the past decade, both in methodology and in the understanding of genomic organization and regulation of gene and pathway expression. The approaches and techniques of molecular biology enable us to ask and answer fundamental questions about many aspects of fungal biology, and open the way to the directed manipulation of fungal genetics. Moreover, this book describes the development of fungal genes and the ways in which these advancements are being exploited in species of economic importance either in biotechnology or in biochemistry. Print ISBN: 978-1-57808-787-7 eBook ISBN: 978-1-4665-0517-9 March 2012, 6 x 9, 400 pp. Suggested Price: $146.95 / £93.00
Print ISBN: 978-1-4665-1529-1 eBook ISBN: 978-1-4665-1530-7 May 2013, 6-1/8 x 9-1/4, 255 pp. Suggested Price: $169.95 / £108.00
Biotechnology in Agriculture and Food Processing
Biotechnology of Plasma Proteins
Opportunities and Challenges
Roger L. Lundblad
Parmjit S. Panesar Sant Longowal Institute of Engineering & Technology, India
Satwinder S. Marwaha Punjab Biotechnology Incubator, India
An instructive and comprehensive overview of the use of biotechnology in various agriculture and food applications, this book discusses the current status of applications for improving quality and productivity of agriculture and food products. It discusses plant tissue culture techniques, genetic engineering in food ingredient production, bio-fertilizers, bio-pesticides, enzymes, genetically modified foods, etc. The book is divided into four parts: fundamental concepts, biotechnology in agriculture, biotechnology in food processing and biotechnological management of crop residues, and waste/by products of agro industries. Print ISBN: 978-1-4398-8836-0 eBook ISBN: 978-1-4398-8838-4 July 2013, 6-1/8 x 9-1/4, 637 pp. Suggested Price: $199.95 / £127.00
Biotechnology
Faizal Bux
Lundblad Biotechnology, Chapel Hill, North Carolina, USA
Discussing the role of plasma proteins in current biotechnology, this book describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, and mass spectrometry, as well as updates not published since 1975. Print ISBN: 978-1-4398-5026-8 eBook ISBN: 978-1-4398-5027-5 August 2012, 6-1/8 x 9-1/4, 460 pp. Suggested Price: $159.95 / £100.00
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Biotechnology in Medical Sciences
Bulbous Plants
Firdos Alam Khan
Edited by
Manipal University, Dubai, United Arab Emirates
Kishan Gopal Ramawat
This book is a comprehensive overview of all the important aspects of medical biotechnology intended for interested, scientifically oriented laypersons who want a relatively low-level presentation of important biotechnology medical specialties such as bacteriology, immunology, recombinant DNA, molecular diagnostics, gene therapy, synthetic biology, tissue engineering, bioethics, IP issues, vaccines, and more.
M.L. Sukhadia University (retired professor), Udaipur, India
Print ISBN: 978-1-4822-2367-5 May 2014, 7 x 10, 480 pp., Soft Cover Suggested Price: $119.95 / £76.99
Biotechnology
Jean-Michel Merillon University of Bordeaux, Villenave d’Ornon, France
Bulbous plants are those with organs for nutrient storage and these include tubers, corms, and bulbs. They can be ornamental or edible, herbaceous or perennial. Important examples of such plants are potato, sweet potato, yam, arrowroot, and dahlias. This book focuses mainly on economically important food crops, their propagation strategies, plant growth and development, tuber quality, and crop protection. Print ISBN: 978-1-4665-8967-4 December 2013, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $129.95 / £82.00
For more information and a complete list of titles, visit us at www.crcpress.com
Cancer Biomarkers Non-Invasive Early Diagnosis and Prognosis Edited by
Debmalya Barh, Angelo Carpi, Mukesh Verma, and Mehmet Gunduz Fatih University Medical School, Anakara, Turkey
Biotechnology
This book classifies available tumor markers according to their principal characteristics and relative methodologies. It presents and discusses the use of the principal tumor markers available for the management of specific cancers (brain, head and neck, oral, gastrointestinal, lung and mesotelioma, urological, gynecological, thyroid, hematological, and melanoma). Each chapter focuses on one type of cancer and is written by physicians or scientists from various countries who blend their clinical experience and scientific expertise in new technologies to provide a definitive account of cancer biomarker discoveries. Print ISBN: 978-1-4665-8428-0 January 2014, 7 x 10, 992 pp. Suggested Price: $209.95 / £134.00
CMOS Nanoelectronics Innovative Devices, Architectures, and Applications Edited by
Nadine Collaert
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Encyclopedia of Biotechnology in Agriculture and Food Edited by
Dennis R. Heldman, Dallas G. Hoover, and Matthew B. Wheeler Focusing on the science and applications of molecular biology to agriculture and foods, this encyclopedia describes the new tools for use in the production of raw agricultural materials and the manufacturing of food products. Two hundred entries cover areas such as cloned animals, genetically modified and drought-resistant plants, biodiversity, and nutritionally enhanced foods. It explores media coverage of biotechnology, associated governmental regulations, consumer acceptance, and environmental issues. Illustrations and comprehensive references complement the text. This reference is also available in an online format. Print ISBN: 978-0-8493-5027-6 July 2010, 8-1/2 x 11, 784 pp. Suggested Price: $463.00 / £295.00
Fundamentals of Biofilm Research Second Edition Zbigniew Lewandowski Montana State University, Bozeman, USA
IMEC, Leuven, Belgium
Haluk Beyenal
This book covers one of the most important device architectures that have been widely researched to extend the transistor scaling: FinFET. Starting with theory, the book discusses the advantages and the integration challenges of this device architecture. It addresses in detail the topics such as high-density fin patterning, gate stack design, and source/drain engineering, which have been considered challenges for the integration of FinFETs. The book also addresses circuit-related aspects, including the impact of variability on SRAM design, ESD design, and high-T operation. It discusses a new device concept: the junctionless nanowire FET.
Washington State University, Pullman, USA
Print ISBN: 978-981-4364-02-7 eBook ISBN: 978-981-4364-03-4 September 2012, 6 x 9, 438 pp. Suggested Price: $149.95 / £95.00
This second edition is a substantial revision of a wellregarded book in biofilm research. Biofilms have taken on added importance in the past several years due to concerns regarding microbial contamination as well as biofilms in water distribution systems and hospital/medical environments. The book includes updates in every chapter and adds three new chapters, namely: Optical Imaging of Biofilms, Biofilms and Microbially Influenced Corrosion, and Biofilms and Microbial Fuel Cells. Another key feature is the incorporation of energy conversion into a number of relevant chapters. Print ISBN: 978-1-4665-5959-2 January 2014, 7 x 10, 660 pp. Suggested Price: $189.95 / £121.00
Electroanalysis with Carbon Paste Electrodes
Genetics, Genomics, and Breeding of Bananas
Ivan Svancara, Kurt Kalcher, Alain Walcarius, and Karel Vytras
Edited by
Series: Analytical Chemistry
Series: Genetics, Genomics and Breeding of Crop Plants
Because of their simple preparation and low expense, carbon pastes as well as carbon paste electrodes are widely used in a myriad of instrumental measurements. With an emphasis on practical applications, this book provides a comprehensive overview of carbon paste electrodes. The text offers a systematic presentation of the individual procedures that are used for determining hundreds of various substances. With a list of up-to-date references, this handy reference source includes specific experimental data and serves as a practical guide for experimental laboratory work. As a result, it is suitable for researchers as well as for students in the field.
Musa is one of three genera in the family of Musaceae. Over 50 species of Musa exist, including bananas and plantains. This book assembles the latest information on the genomic research of this genus. A group of leading experts in Musa genetics, genomics, and breeding provide basic as well as advanced information for those interested in learning more about the banana genome. The accessible style is easily understood by students and researchers, making the book an ideal springboard for those looking to do expanded research into this crop.
Print ISBN: 978-1-4398-3019-2 eBook ISBN: 978-1-4398-3020-8 March 2012, 7 x 10, 666 pp. Suggested Price: $135.95 / £86.00
Michael Pillay, George Ude, and Chittaranjan Kole
Print ISBN: 978-1-57808-788-4 eBook ISBN: 978-1-4665-0516-2 March 2012, 6 x 9, 350 pp. Suggested Price: $125.95 / £81.00
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Handbook of Biofunctional Surfaces
Microspheres and Microcapsules in Biotechnology
Edited by
Design, Preparation and Applications
Wolfgang Knoll
Edited by
Austrian Institute of Technology, Vienna
Guanghui Ma and Zhi-Guo Su
Print ISBN: 978-981-4316-63-7 eBook ISBN: 978-981-4364-18-8 May 2013, 6 x 9, 1184 pp. Suggested Price: $500.00 / £318.00
Chinese Academy of Sciences, Beijing
This book focuses on new microspheres and microcapsules specifically designed and prepared for application in the fields of biotechnology and biopharmaceuticals involving bioreaction, bioseparation, bioformulation, biodetection, and other new bioapplications. It provides a deep knowledge about the principles of design, preparation methods, and application results of new microspheres and microcapsules for each bioapplication area. The book also presents problems that need to be studied further and comments on the future prospects of microspheres and microcapsules. Print ISBN: 978-981-4316-47-7 eBook ISBN: 978-981-4364-62-1 January 2013, 6 x 9, 552 pp. Suggested Price: $249.95 / £159.00
Inside the Photon A Journey towards Health
Multifunctional Molecular Materials
Tony Fleming
Edited by
Biophotonics Research Institute, Highett, Australia
Lahcene Ouahab
Elizabeth Bauer
Biotechnology
It is still the very beginning of generating a better understanding of what is needed to make an organism tolerate implants, to guarantee the bidirectional communication between microelectronic devices and living tissue or to simply construct an interactive biocompatibility of surfaces in general. This book describes the design, synthesis, assembly and characterization, and the bio-(medical) application of interfacial layers on solid substrates with molecularly or supra-molecularly controlled architectures. Experts in the field describe their contributions that have been developed in recent years.
Laboratoire Sciences Chimiques de Rennes, France
Biophotonics Research Institute, Highett, Australia
This book describes the newly discovered layer of biophotonics underlying all atomic chemistry and biochemistry. As with the variety of snowflakes, the range in biological species within flora for instance is dependent on this biophotonic layer of interaction within atomic and biomolecular structures. The book examines the phonon, the quantum of acoustic or vibrational energy, and alongside the photon. Hence the ‘biophonon’ sits aside the biophoton as an element within biological structures. Sounds can create structure in the same way biophotons can use structure to communicate. Print ISBN: 978-981-4241-40-3 November 2013, 6 x 9, 250 pp. Suggested Price: $149.95 / £95.00
This book provides a comprehensive overview on multifunctional molecular materials that involve coexistence or interplay or synergy between multiple physical properties focusing on electrical conductivity, magnetism, single-molecule magnets behavior, chirality, spin crossover, and luminescence. The book’s coverage ranges from transition metals and lanthanide coordination complexes to genuine organic materials. The book also discusses some potentialities of applications of these materials in molecule-based devices. Print ISBN: 978-981-4364-29-4 eBook ISBN: 978-981-4364-30-0 January 2013, 6 x 9, 314 pp. Suggested Price: $149.95 / £95.00
37 Labs on Chip Principles, Design, and Technology
Noninvasive Molecular Markers in Gynecologic Cancers
Eugenio Iannone
Edited by
Dianax Study Group Founder and President, Milano, Italy
Debmalya Barh
Series: Devices, Circuits, and Systems
This book provides a complete reference for the complex field of labs-on-chip for applications in biotechnology. The book presents (LOC) in an accurate and complete technical form, all the elements related to LOC technology and applications. It is useful both to the professional who wants to approach a new field and to the specialist of one particular aspect who wants to gain an overall view. It is based on realistic applications matured in a long work with medical researchers, and includes strong theoretical explanations of design techniques alongside technology issues. Print ISBN: 978-1-4665-6072-7 June 2014, 7 x 10, 800 pp. Suggested Price: $189.95 / £121.00
Institute of Integrative Omics and Applied Biotechnology (IIOAB), Purba Medinipur, West Bengal, India
In cancer treatment, non-invasive diagnosis can avoid complications of biopsy and other unfavorable impacts on patient health. DNA, methylation, SNPs, miRNA, mRNA, protein, autoantibodies, metabolite, and omics-based markers from remote media such as blood, plasma, and urine are emerging as noninvasive molecular markers with high specificity and sensitivity toward several cancers. In many instances, these markers are also emerging as next-generation personalized diagnostics and targets or therapeutics for personalized cancer treatment. This book classifies the available molecular tumor markers according to their principal characteristics and relative methodologies. Print ISBN: 978-1-4665-6938-6 May 2014, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $149.95 / £95.00
For more information and a complete list of titles, visit us at www.crcpress.com
OMICS
Probiotics
Applications in Biomedical, Agricultural, and Environmental Sciences
Immunobiotics and Immunogenics
Edited by
Haruki Kitazawa, Julio Villena, and Susana Alvarez
Debmalya Barh, Vasudeo Zambare, and Vasco Azevedo
Biotechnology
Featuring contributions from active researchers around the world, this book explores current and emerging fields such as glycomics, miRNA, metagenomics, and environomics and their various applications. In one volume, it examines a wide range of applications across the life sciences, demonstrating the real diversity of omics. This timely book discusses toxicogenomics in the assessment of environmental pollutants, plant metabolomics, nutrigenomics and its therapeutic applications, microalgal omics, omics for biofuel development, omics approaches for crop improvement and environmental sustainability, breast cancer biomarkers, and much more. Print ISBN: 978-1-4665-6281-3 eBook ISBN: 978-1-4665-6283-7 March 2013, 7 x 10, 713 pp. Suggested Price: $169.95 / £108.00
OMICS Applications in Crop Science Edited by
Debmalya Barh Institute of Integrative Omics and Applied Biotechnology (IIOAB), Purba Medinipur, West Bengal, India
The omics era in plant science started when genome sequencing commenced, and since then several plant genomes have been completely sequenced and extraction of the genomic information has been implemented for production of highyielding and disease/stress-resistant plants. With the advent of high-throughput omics technologies, the number of complete plant genome sequences is rapidly increasing. This genomic information, along with transcriptomics-, porteomics-, and metabolomics-based approaches, is leading plant sciences toward the nextgeneration green revolution. This book incorporates the latest research in this important field.
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Print ISBN: 978-1-4665-8525-6 January 2014, 7 x 10, 702 pp. Suggested Price: $189.95 / £121.00
Edited by
Written by international experts, this book reviews recent, cutting-edge research on the use of immunoregulatory probiotics (immunobiotics) and their bioactive compounds (immunogenics) to prevent disease and improve health. Each chapter provides critical insight, reviews current research, discusses future perspective, and stimulates discussion. The book also discusses novel applications of immunobiotics, such as their use in respiratory infections and regulation of the interaction between inflammation and coagulation, as well as their effect on hematopoiesis. Print ISBN: 978-1-4822-0684-5 eBook ISBN: 978-1-4822-0685-2 September 2013, 6-1/8 x 9-1/4, 412 pp. Suggested Price: $129.95 / £82.00
RNA Nanotechnology Edited by
Bin Wang Marshall University, Huntington, West Virginia, USA
A comprehensive volume, this books details details the traditional approaches and the latest developments in the field of RNA-related technology. It targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications. Print ISBN: 978-981-4411-64-6 November 2013, 6 x 9, 450 pp. Suggested Price: $149.95 / £95.00
Omics Technologies and Crop Improvement
Stem Cell Engineering Handbook
Edited by
Edited by
Noureddine Benkeblia
Xuejun Wen
Department of Life Scienses, University of West Indies, Kingston, Jamaica
Clemson University, Charleston, South Carolina, USA
Omics technologies are modern approaches that give insight into the plant genome and its analysis, using DNA-based methods for variety identification, RNA interference, elicitor biotechnology, and marker-assisted selection and breeding applications in some major crops. This book reviews data on food sciences and omics and introduces researchers to the benefits of using these technologies. It covers a wide range of crop science categories and is organized to give a broad view on how omics can help crop science and horticulture.
Stem cell engineering allows scientists to manipulate stem cells artificially for the purpose of studying and controlling their survival, potency, proliferation, migration, specific differentiation, plasticity, immunocompatibility, fate in vivo, and other properties. This new area holds great promise for researchers using stem cells for testing the safety and effects of new drugs, for the treatment of disease, and for the regeneration of injured tissues. This volume brings researchers from engineering, chemistry, physics, and biology together to discuss basic and advanced topics in this burgeoning field.
Print ISBN: 978-1-4665-8668-0 June 2014, 7 x 10, 850 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4200-9005-5 June 2014, 7 x 10, 1000 pp. Suggested Price: $189.95 / £121.00
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Viral Diagnostics
Textbook
Edited by
Analytical Chemistry for Technicians
Robert S. Marks, Leslie Lobel, and Amadou Sall
Fourth Edition
With an emphasis on the newer technologies in development, this book covers a spectrum of topics in the diagnostics and monitoring of viral ailments. The book emphasizes optical fiber and electrochemical immunosensors, reverse genetics, and luminescent molecular imprints of neutrophil biomarkers. The contributors comprise experts from the fields of epidemiology, biotechnology, and virology, as well as industry, technologies, and the clinics. With coverage of viruses ranging from influenza to emerging ebola, this text provides readers with a survey of various aspects of the field as well as a glimpse of future possibilities.
John Kenkel
Print ISBN: 978-981-4364-43-0 February 2014, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00
Emeritus, Southeast Community College, Lincoln, Nebraska, USA
Covering classic quantitative analysis and related experiments, this thoroughly updated fourth edition is designed to be a powerful training tool for chemistry-based laboratory technicians. Emphasizing the practical aspects, the book begins with an introduction to analytical science and follows with a practical approach to the complex world of sophisticated electronic instrumentation commonly used in real-world laboratories. Providing a foundation for the two key qualities—the analytical mindset and a basic understanding of the analytical instrumentation—this book helps prepare individuals for success on the job. Print ISBN: 978-1-4398-8105-7 eBook ISBN: 978-1-4665-9544-6 August 2013, 7 x 10, 537 pp. Suggested Price: $99.95 / £49.99
Advances in Chromatography
CMOS
Volume 52 Edited by
Front-End Electronics for Radiation Sensors
Eli Grushka
Angelo Rivetti
Hebrew University of Jerusalem, Israel
Istituto Nazionale di Fisica Nucleare, Torino, Italy
Nelu Grinberg
Series: Devices, Circuits, and Systems
Boehringer-Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut, USA Series: Advances in Chromatography, 52
For more than four decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 52, the series editors have invited established, well-known chemists from across the globe to offer cutting-edge reviews on their areas of expertise. The clear presentation of topics and vivid illustrations for which this series has become known makes the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill. Print ISBN: 978-1-4822-2350-7 March 2014, 6-1/8 x 9-1/4, 264 pp. Suggested Price: $169.95 / £108.00
This book offers a comprehensive treatment of frontend electronics for radiation detection. It discusses the fundamental principles of signal processing for radiation detectors and describes circuits at the level of functional building blocks, omitting transistor-level implementation. It also covers important systemlevel topics commonly found in the world of front-end electronics for radiation sensors. The book develops the topics in detail, with a constant focus on practical problems and real implementation examples that provide insights and stimuli for more experienced engineers already working in the field. Print ISBN: 978-1-4665-6310-0 June 2014, 6-1/8 x 9-1/4, 500 pp. Suggested Price: $179.95 / £114.00
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Advances in Chromatography, Volume 51
Dynamic Force Spectroscopy and Biomolecular Recognition
Print ISBN: 978-1-4665-6965-2 eBook ISBN: 978-1-4665-6966-9 July 2013, 6-1/8 x 9-1/4, 328 pp. Suggested Price: $229.95 / £146.00
Edited by
Anna Rita Bizzarri and Salvatore Cannistraro Universita Della Tuscia, Viterbo, Italy
Advances in Chromatography, Volume 50 Edited by
Print ISBN: 978-1-4398-5844-8 eBook ISBN: 978-1-4398-5845-5 January 2012, 6-1/8 x 9-1/4, 465 pp. Suggested Price: $200.00 / £153.00
Biotechnology / Methods & Instrumentation
Advances and Applications
Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. This book covers the most recent ideas and advances in the field of DFS applied to biorecognition. Leading experts in the field offer their perspectives on such important topics as atomic force microscopy, force spectroscopy, interaction geometries, and immobilization strategies. Print ISBN: 978-1-4398-6237-7 eBook ISBN: 978-1-4398-6238-4 January 2012, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $135.95 / £86.00
For more information and a complete list of titles, visit us at www.crcpress.com
Forensic DNA Analysis
Textbook
Current Practices and Emerging Technologies
David M. Jameson
Edited by
Jaiprakash G. Shewale Genetic Systems, Life Technologies Corporation, Foster City, California, USA
Ray H. Liu Forensic Science Review, Vancouver, Washington, USA
Methods & Instrumentation
Application areas in the field of forensic DNA analysis include paternity testing, forensic casework, family lineage studies, identification of human remains, and DNA databasing. This volume explores the fundamental principles and the application of technologies for each aspect of forensic DNA analysis. Topics include methods and the best practices for DNA isolation from forensic biological samples and human remains, messenger RNA and small (micro) RNA profiling, real-time polymerase chain reaction (PCR) methods, capillary electrophoresis (CE), next-generation short tandem repeat (STR) genotyping kits, and mitochondrial DNA (mtDNA) sequence analysis.
University of Hawaii, Manoa, USA
A concise introduction to fundamental principles, this book presents the most important aspects of fluorescence spectroscopy, particularly as they are applied to biology, biochemistry, and biophysics. The author focuses on the essential aspects of fluorescence to encourage readers to design experiments, begin their own fluorescence measurements, and access the literature with greater comprehension. After a general definition of the field and an overview of the nature of light and absorption by biomolecules, the text covers instrumentation, emission spectra, excitation spectra, polarization, anisotropy, quenching, time-resolved methods, and FRET. Print ISBN: 978-1-4398-0604-3 February 2014, 6-1/8 x 9-1/4, 309 pp. Suggested Price: $79.95 / £49.99
Print ISBN: 978-1-4665-7126-6 eBook ISBN: 978-1-4665-7136-5 August 2013, 7 x 10, 445 pp. Suggested Price: $99.95 / £63.99
Identifying Microbes by Mass Spectrometry Proteomics Edited by
Charles H. Wick Edgewood Chemical Biological Center, Aberdeen Proving Ground, Maryland, USA
40
Introduction to Fluorescence
This book is a comprehensive resource on using mass spectrometry proteomics (MSP), a powerful new technique combining hardware and software, as a highly accurate means for the detection, identification, and classification of microbes including unknown or unsequenced bacteria, viruses, and fungi. Chapters describe various mass analyzers, methods for analyzing MS data files, genomic approaches, sample collection and processing, software and bioinformatics, and examples of application of the method. This book also surveys commercially available MS-based platforms suitable for MSP and discusses future trends in these groundbreaking techniques. Print ISBN: 978-1-4665-0494-3 eBook ISBN: 978-1-4665-0496-7 September 2013, 6-1/8 x 9-1/4, 289 pp. Suggested Price: $139.95 / £89.00
Introduction to GC-MS Coupling Stéphane Bouchonnet Without neglecting the fundamental theory, this book emphasizes the practical aspects of gas chromatographymass spectrometry (GC-MS). It discusses important topics such as choosing the most successful device for a given application and the problems usually encountered by novice users and ways to solve them. Additional topics include acquisition modes in GC-MS, quadrupolar analyzer performance, quantification by GC-MS, spectra databases for GC-MS, dissociation mechanisms, and mass spectra interpretation. The book supports theoretical demonstrations with numerous examples and figures to assist with reader assimilation. Print ISBN: 978-1-4665-7251-5 eBook ISBN: 978-1-4665-7252-2 February 2013, 6-1/8 x 9-1/4, 228 pp., Soft Cover Suggested Price: $79.95 / £49.99
Textbook
Textbook
Introduction to Experimental Biophysics
Introduction to Instrumentation in Life Sciences
Biological Methods for Physical Scientists
Prakash Singh Bisen
Jay Nadeau
Anjana Sharma
McGill University, Montreal, Quebec, Canada
Defense Research & Development Establishment, Gwalior, India Rani Durgavati University, Jabalpur, India
A practical companion for physical scientists investigating wet laboratory experiments and biological research areas, this book gives a clear understanding of what is experimentally feasible. Introducing basic terminology and concepts, the text begins with simple, fundamental methods and builds gradually to more advanced techniques. Organized into three main sections addressing genes, proteins, and expression systems, this book employs a straight-forward structure allowing readers to follow the process involved in the production of nucleic acids and proteins and the different levels of purification required for each type of analysis.
Addressing aspects of instrumentation that hold the keys for cutting-edge research and innovative applications, this book is designed to serve a wide range of students and researchers in diversified fields of life sciences, including pharmacy, biotechnology, microbiology, biochemistry, and environmental sciences. The book is unique in its broad subject coverage, incorporating fundamental techniques as well as applications of modern molecular and proteomic tools that are the basis for state-of-the-art research. It includes well-illustrated diagrams to explain the principles and theories behind the instruments described.
Print ISBN: 978-1-4398-2953-0 eBook ISBN: 978-1-4398-2954-7 September 2011, 7 x 10, 672 pp., Soft Cover Suggested Price: $98.95 / £62.99
Print ISBN: 978-1-4665-1240-5 eBook ISBN: 978-1-4665-1242-9 September 2012, 7 x 10, 383 pp., Soft Cover Suggested Price: $83.95 / £51.99
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LC-NMR
Second Edition
Expanding the Limits of Structure Elucidation
Stephen Shrader
Nina C. Gonnella
Shrader Laboratories, Inc., Detroit, Michigan, USA
Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut, USA
Mass spectrometry has clearly become an integral part of the organic chemistry laboratory. This book provides an introduction to mass spectrometry and its applications suitable for undergraduates and organic chemists who wish to add mass spectrometry to their repertoire of useful analytical tools. Basic principles of mass spectrometry, the processes that occur in the instrument, interpretation of mass spectra, and the other techniques such as GC-MS and LCMS are described in easy-to-understand language. The examples provided in the text represent a cross section of organic chemistry.
Series: Chromatographic Science Series
Print ISBN: 978-1-4665-9584-2 November 2013, 6-1/8 x 9-1/4, 189 pp., Soft Cover Suggested Price: $79.95 / £49.99
Ion Mobility Spectrometry
This book presents a comprehensive overview of key concepts in HPLC and NMR required to achieve definitive structure elucidation at low levels of analytes. It provides guidance in setting up LC-NMR systems, discussion of LC methods compatible with NMR, and an update on recent hardware and software advances. It describes numerous NMR collection strategies and presents an overview of NMR experiments and techniques used in structure elucidation. It also discusses a range of applications with pharmaceutical and academic utility, exploring novel technologies as well as future directions. Print ISBN: 978-1-4398-7506-3 eBook ISBN: 978-1-4398-7507-0 March 2013, 6-1/8 x 9-1/4, 301 pp. Suggested Price: $129.95 / £82.00
Third Edition
Linear and Chiral Dichroism in the Electron Microscope
G.A. Eiceman, Z. Karpas, and Herbert H. Hill, Jr.
Edited by
Beginning with a thorough discussion of the fundamental theories and physics of ion mobility, this third edition continues with a detailed description of the technology and applications. It discusses the recent advances in instrumentation and newly pioneered applications. Each chapter is thoroughly updated, with new information on present trends in IMS and coverage of FAIMS and DMS/MS. Significant expansion to the Biological and Biomedical section is provided, with an emphasis on LC ESI Mobility MS or ESI Mobility MS, including IMS TOF. Print ISBN: 978-1-4398-5997-1 December 2013, 6-1/8 x 9-1/4, 436 pp. Suggested Price: $149.95 / £95.00
Peter Schattschneider Vienna University of Technology, Austria
Methods & Instrumentation
Introductory Mass Spectrometry
This book describes energy loss magnetic chiral dichroism (EMCD), a phenomenon in energy loss spectroscopy discovered in 2006. EMCD is the equivalent of XMCD but is based on fast probe electrons in the electron microscope. A spatial resolution of 2 nm has been demonstrated, and the latticeresolved mapping of atomic spins appears feasible. EMCD is, thus, a promising technique for magnetic studies on the nanometer and sub-nanometer scale, providing the technical and logistic advantages of electron microscopy, such as in situ chemical and structural information, easy access, and low cost. Print ISBN: 978-981-4267-48-9 eBook ISBN: 978-981-4303-17-0 March 2012, 6 x 9, 278 pp. Suggested Price: $149.95 / £95.00
41 Laboratory Protocols in Applied Life Sciences
Mass Spectrometry for the Novice
Prakash Singh Bisen
John Greaves
Defense Research & Development Establishment, Gwalior, India
University of California, Irvine, USA
This manual includes details of methodologies used in diverse disciplines of life sciences including biotechnology, pharmaceutical sciences, medical sciences, and related fields. It provides the comprehensive information required to build a firm foundation in the life sciences. Due emphasis is given to techniques encountered in practical classes and high-throughput techniques involved in modern eras of commercialization and product inventories. Well illustrated to explain the theories behind each exercise, this book covers both basic techniques and new, advanced techniques that continue to evolve and change.
Mount Sinai School of Medicine, New York, USA
Print ISBN: 978-1-4665-5314-9 February 2014, 7 x 10, 1844 pp. Suggested Price: $179.95 / £114.00
John Roboz Using simple language, color figures, clever cartoons, and assuming no prior knowledge, this book provides an understandable introduction to mass spectrometry. It presents novice users with detailed descriptions of principles of instrument operations and analytical strategies. The book focuses on commonly used instrument systems and analytical strategies covering chemical, environmental, biological, and medical research, helping novices make informed choices. A unique and brief chapter summarizes the absolute essentials (a set of take-home messages). A series of diverse examples from the literature is provided. Print ISBN: 978-1-4200-9418-3 eBook ISBN: 978-1-4200-9420-6 October 2013, 6-1/8 x 9-1/4, 309 pp., Soft Cover Suggested Price: $69.95 / £44.99
For more information and a complete list of titles, visit us at www.crcpress.com
Phenomics
Quantitative Proteome Analysis
Edited by
Methods and Applications
John M. Hancock Cambridge University, UK
Methods & Instrumentation / Nanobiotechnology 42
Phenomics is the new discipline of using standardized measurement techniques to characterize the phenotypic effects of random or systematic genome modifications (e.g. randomly generated mutations or systematic gene knockouts). This approach is now being used in an increasing range of species and systems. In this book, experts working in phenomics in most of the major species and systems that are currently being studied present overviews of the field from their different, but overlapping, perspectives. Print ISBN: 978-1-4665-9095-3 December 2013, 6-1/8 x 9-1/4, 340 pp. Suggested Price: $129.95 / £82.00
Practical Guide and Spectral Atlas for Interpretive Near-Infrared Spectroscopy Second Edition Jerry Workman, Jr. Unity Scientific LLC, Brookfield, Connecticut, USA
Lois Weyer Landenberg, Pennsylvania, USA
Interpretive spectroscopy provides a basis for the establishment of cause-andeffect relationships between spectrometer response and the chemical properties of the samples. Without established cause-effect relationships, the measured data will have no true predictive significance. This interpretive process is key for achieving an analytical understanding of the measurement. The popular first edition of this text delivered a unique focus on structure correlation and interpretation of spectra for the practitioner. The thoroughly updated and revised second edition continues the tradition and includes a full library of color spectra in a larger format to ensure clarity and reader comprehension.
Edited by
Kazuhiro Imai Musashino University, Tokyo, Japan
Sam Li Fong Yau National University of Singapore
This book focuses on the advantages and disadvantages of each of the commonly used quantitative proteomic methods in terms of accuracy, sensitivity, and reproducibility. It also concentrates on the effective applications of these methods that resulted in many discoveries of the role of the proteins expressed in living cells and biological fluids. The first part of the book focuses on the description of advantages and disadvantages of each of the commonly used quantitative proteomic methods in terms of accuracy, sensitivity, and, especially, reproducibility. The second part of the book focuses on providing concise descriptions of the effective applications of these methods to demonstrate how they have resulted in many important discoveries of the roles of the proteins expressed in living cells. Print ISBN: 978-981-4316-51-4 eBook ISBN: 978-981-4316-98-9 August 2013, 6 x 9, 312 pp. Suggested Price: $199.95 / £127.00
Atomic Force Microscopy in Nanobiology Edited by
Kunio Takeyasu Kyoto University, Japan
Edited by Dr. Takeyasu, with contributions from leading scientists in the field of nanobiology, this book provides an overview of modern atomic force microscopy (AFM) technologies. It covers basic AFM protocols, newly developed technologies, and recent applications of AFM technologies in biological sciences. There are many nanotechnology books that focus on materials, instruments, and applications in engineering and medicine, but only a few of them are directed toward basic biological sciences. This book bridges that gap.
Print ISBN: 978-1-4398-7525-4 eBook ISBN: 978-1-4398-7526-1 April 2012, 8-1/2 x 11, 326 pp. Suggested Price: $200.00 / £133.00
Print ISBN: 978-981-4411-58-5 January 2014, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00
Practical Guide to ICP-MS
Bionanotechnology
A Tutorial for Beginners, Third Edition
Maheshwar Sharon
Robert Thomas
Madhuri Sharon
Scientific Solutions, Gaithersburg, Maryland, USA Series: Practical Spectroscopy
Presenting an in-depth discussion of the fundamental principles, analytical advantages, and practical capabilities of ICP-MS, this volume offers key concepts in a readerfriendly format suitable for novices. Written by an insider with more than 25 years of experience in product development, customer support, and technical marketing for an ICP-MS instrument vendor, the book highlights this powerful ultra trace-element technique as a practical solution to real-world problems. The new edition covers new technologies and applications, and discusses nonstandard sampling accessories and much more. Print ISBN: 978-1-4665-5543-3 eBook ISBN: 978-1-4665-5544-0 April 2013, 6-1/8 x 9-1/4, 446 pp. Suggested Price: $99.95 / £63.99
IIT Bombay (Retired), Birla College, Nanotechnology Research Center, India Monad Nanotech Pvt. Limited, Mumbai, India
Highlighting the human applications of the science, this volume discusses the fundamental concepts and underlying science of bionanotechnology, and the bionanomachines that result from research into this exciting new field. Distilling the authors’ research and groundbreaking original experimentation, chapters cover bionanomachines and their use with and manipulation of DNA, RNA, proteins, carbohydrates, and lipids. Welldocumented and authoritative, this book offers students and scientists alike the foundational information required to advance this powerful and potentially lifealtering field. Print ISBN: 978-1-4398-5214-9 May 2012, 6 x 9, 300 pp. Suggested Price: $89.95 / £51.99
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Biophysics for Beginners
Cancer Nanotechnology
A Journey through the Cell Nucleus Helmut Schiessel
Principles and Applications in Radiation Oncology
Leiden University, The Netherlands
Edited by
Print ISBN: 978-981-4241-65-6 September 2013, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00
Sang Hyun Cho Georgia Institute of Technology, Atlanta, USA
Sunil Krishnan University of Texas MD Anderson Cancer Center, Houston, USA
This comprehensive volume demonstrates how the unique physicochemical properties of nanoparticles lead to novel strategies for cancer treatment and detection. After an introduction to the first principles of radiation physics and radiation biology, the book discusses fabrication of nanoparticles, safety of nanoparticles, and the quantification of nanoparticle accumulation within tissues. Successive chapters highlight the computational and experimental techniques that underlie the use of nanoparticles for imaging and treating tumors. The book concludes with regulatory issues related to human use and a summary of envisioned clinical translation. Print ISBN: 978-1-4398-7875-0 eBook ISBN: 978-1-4398-7876-7 January 2013, 8-1/2 x 11, 284 pp. Suggested Price: $169.95 / £108.00
Biosensors Based on Nanomaterials and Nanodevices
Cellular In Vitro Testing
Edited by
Edited by
Jun Li
John Haycock, Arti Ahluwalia, and J. Malcolm Wilkinson
Kansas State University, Manhattan, USA
Nianqiang Wu West Virginia University, Morgantown, USA Series: Nanomaterials and their Applications
This book is a useful source for readers, from beginners to expert researchers, to get a quick overview of exciting potentials and critical challenges of emerging biosensors based on nanomaterials and nanodevices for future health monitoring, disease diagnosis, and therapeutic treatments. The book highlights developments in biosensors based on nanomaterials and nanodevices in about 10 to 15 chapters on focused topics. With an emphasis on the unique signal transducing mechanisms and potential applications of nanoscale biosensors, it is intended to serve as a comprehensive source for researchers, graduate students, and industrial engineers in this area.
Methods and Protocols
Focusing on new 3-D in vitro methods, this book brings together examples of leading-edge work being conducted internationally for improving in vitro cell culture methods. It highlights the use of systems for enabling cell culture under laminar flow and the use of 3-D scaffolds for providing cells with a structure which replicates the function of the extracellular matrix and encouraging interactions more akin to an in vivo environment. Chapters cover state-of-the-art protocols for bioreactor systems, in vitro toxicity methods, non-invasive imaging, 3-D cell cultures, stem cell usage, and the integration and use of novel scaffolds. Print ISBN: 978-981-4364-97-3 February 2014, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4665-5151-0 December 2013, 7 x 10, 520 pp. Suggested Price: $159.95 / £99.00
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Cadmium Telluride Quantum Dots
Chemotherapy-Induced Neuropathic Pain
Advances and Applications
Edited by
Robert B. Raffa, Richard Langford, Joseph V. Pergolizzi, Jr., Frank Porreca, and Ronald J. Tallarida
Edited by
John Donegan and Yury Rakovich Trinity College Dublin, Ireland
Among nanomaterials, CdTe holds special technological importance as the only known II–VI material that can form conventional p–n junctions. This makes CdTe very important for the development of novel optoelectronic devices such as light-emitting diodes, solar cells, and lasers. This book focuses on CdTe quantum dots and addresses their synthesis, assembly, optical properties, and applications in biology and medicine. It makes for a very informative reading for anyone involved in nanotechnology and will also benefit those scientists who are looking for a comprehensive account on the current state of quantum dot–related research. Print ISBN: 978-981-4316-05-7 October 2013, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00
Nanobiotechnology
This textbook gives compact introductions to the basics of the field (in areas such as molecular cell biology and statistical physics) and then presents in-depth discussions of more advanced biophysics subjects, progressing to state-of-the-art experiments and their theoretical interpretations. The book is unique by offering a general introduction to biophysics, yet at the same time restricting itself to processes that occur inside the cell nucleus and that involve biopolymers (DNA, RNA, and proteins). This creates an accessible read for beginners and a springboard for specialists who wish to continue their study in more detail.
Written for pain management practitioners, oncologists, pharmacologists, and primary care practitioners as well as students in these fields, this reference provides insight into the chemotherapy-induced neuropathic pain that a significant number of cancer survivors suffer. It reviews the basic and clinical research into the normal physiology of pain transmission pathways, neuropathic pain pathology, the chemotherapeutic drug mechanisms of action and adverse effects, and chemotherapy-induced neuropathy. The book covers both basic science and clinical research and provides unique insight into current drug discovery efforts. Print ISBN: 978-1-4398-6218-6 eBook ISBN: 978-1-4398-6219-3 July 2012, 6-1/8 x 9-1/4, 233 pp. Suggested Price: $149.95 / £95.00
For more information and a complete list of titles, visit us at www.crcpress.com
The Clinical Nanomedicine Handbook
Electrokinetic Particle Transport in Micro-/Nanofluidics
Sara Brenner
Direct Numerical Simulation Analysis
University at Albany, State University of New York, USA
Nanobiotechnology
Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers, and scientists, this volume discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty, examining nanotechnology’s potential to solve medical problems. It explores nanotechnology applications for infectious diseases, in dermatology, ophthalmology, urology, in preventive medicine and public health, and in vascular medicine and surgery. The book also examines therapeutic applications and targeted delivery of nanomedicines and nanopharmaceutical products. Print ISBN: 978-1-4398-3478-7 eBook ISBN: 978-1-4398-3479-4 October 2013, 7 x 10, 365 pp. Suggested Price: $199.95 / £127.00
Consumers and Nanotechnology Deliberative Processes and Methodologies Harald Throne-Holst, Eivind Soto, Pal Strandbakken, and Gerd Scholl In recent years, questions about democratic influence on science and technology have received much attention. The lesson from the European unrest over GMO is that consumer-citizens will react negatively to being forced to accept the introduction of new, partly untested technologies. A number of political bodies have started to involve citizens and to consider their concerns, attitudes, hopes, and worries in the early stages of the coming nano revolution. This volume assembles the contributions of experts who analyze a number of these deliberations, mainly in the European Union and the United States. The book analyzes citizen-oriented deliberations along with more stakeholderoriented deliberations.
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Print ISBN: 978-981-4316-16-3 eBook ISBN: 978-981-4364-34-8 April 2013, 6 x 9, 272 pp. Suggested Price: $149.95 / £95.00
Electrochemical Biosensors Edited by
Serge Cosnier Université Joseph Fourier, Grenoble Cedex, France Series: Pan Stanford Series on the High-Tech of Biotechnology
This book provides an overview of biosensors based on amperometry, conductimetry, potentiometry, square-wave voltammetry, impedance, and electrochemiluminescence and describes the use of ultramicroelectrodes for the realtime monitoring and understanding of exocytosis. Areas of particular interest are the use of silver and gold nanoparticles for signal amplification, photocurrent transduction, and aptamer design. Moreover, advanced insights in the innovative concept of self-powered biosensors derived from biofuel cells are also discussed. Print ISBN: 978-981-4411-46-2 December 2013, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00
Shizhi Qian Department of Mechanical and Aerospace Engineering, Old Dominion University, Norfolk, Virginia, USA
Ye Ai Bioscience Division, Los Alamos National Laboratory, New Mexico, USA Series: Surfactant Science
This book provides a fundamental understanding of the electrokinetic particle transport in micro-/nanofluidics, involving electrophoresis, dielectrophoresis, electroosmosis, and induced-charge electroosmosis. It emphasizes the direct numerical simulation of electrokinetic particle transport phenomena, plus several supportive experimental studies. The authors use COMSOL Multiphysics® to conduct all the numerical simulations presented and include the corresponding script files in the book. The book is suitable as a resource for researchers in micro-/nanofluidics and as a supplementary textbook for courses in electrokinetic transport phenomena in micro-/nanofluidics. Print ISBN: 978-1-4398-5438-9 eBook ISBN: 978-1-4398-5439-6 June 2012, 6 x 9, 398 pp. Suggested Price: $135.95 / £86.00
Extracellular Vesicles in Health and Diseases Edited by
Paul Harrison, Chris Gardiner, and Ian L. Sargent This book stems from the first international meeting on Microvesicles and Nanovesicles in Health and Disease held at Magdalen College, Oxford in 2010. The meeting brought together a range of experts from around the world to discuss advances in this field. Key to the study of these vesicles is the availability of methodologies for their measurement in biological fluids. A main focus of the meeting was on a range of exciting new technologies which have been developed for this purpose. Print ISBN: 978-981-4411-98-1 December 2013, 6 x 9, 500 pp. Suggested Price: $199.95 / £127.00
Textbook
From MEMS to Bio-MEMS and Bio-NEMS Manufacturing Techniques and Applications Marc J. Madou University of California, Irvine, USA
This book details manufacturing techniques applicable to bio-nanotechnology. After reviewing MEMS techniques, materials, and modeling, the author covers nanofabrication, genetically engineered proteins, artificial cells, nanochemistry, and self-assembly. He also discusses scaling laws in MEMS and NEMS, actuators, fluidics, and power and brains in miniature devices. He concludes with coverage of various MEMS and NEMS applications. This color text offers end-of-chapter problems, worked examples throughout, extensive references, and PowerPoint slides for download. Print ISBN: 978-1-4200-5516-0 eBook ISBN: 978-1-4398-9182-7 June 2011, 8-1/2 x 11, 650 pp. Suggested Price: $109.95 / £69.99
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Handbook of Chemotherapeutic Engineering
Horizons in Clinical Nanomedicine
Concepts, Feasibility, Safety, and Prospects — A Tribute to Shu Chien’s 80th Birthday
Edited by
Feng Si-shen, Stanford Chong, and Jenny Rompas This book is a collection of the major publications of the authors in the emerging area of chemotherapeutic engineering. It describes and demonstrates the concept, feasibility, safety, and prospect of chemotherapeutic engineering through a full spectrum of proof-of-concept experiments from design, characterization, in vitro cellular uptake, cytotoxicity, to in vivo pharmacokinetics, biodistribution, and xenograft tumor model of the various nanocarriers, such as prodrugs, micelles, liposomes, and nanoparticles of biodegradable polymers. Print ISBN: 978-981-4463-14-0 November 2013, 9 x 6, 1000 pp. Suggested Price: $500.00 / £318.00
Handbook of Dynein
Aristotle University of Thessaloniki, Greece
Nanomedicine—the application of nanotechnology to health sciences—has the potential to address many important medical problems by exploiting the improved and novel physical/chemical characteristics of nanostructured materials and devices. This book provides a comprehensive overview on the forefront of developments of nanotechnology in various domains of clinical medicine, such as cardiology, oncology, pharmacology, immunology, dermatology, virology, hematology, orthopaedics, embryology and congenital defects, dentistry, and tissue engineering. It also discusses the toxicology aspects of the engineered nanomaterials. Print ISBN: 978-981-4411-56-1 January 2014, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00
Textbook
Edited by
Keiko Hirose National Institute of Advanced Industrial Science & Technology, Ibaraki, Japan
Learning Bio-MicroNanotechnology Mel I. Mendelson
Linda A. Amos
Loyola Marymount University, Los Angeles, California, USA
MRC Laboratory of Molecular Biology, Cambridge, UK
A primary text for undergraduate nanotechnology courses, this book is designed for students who lack a cross-disciplinary background and knowledge of microand nano-technology. Clearly and concisely written, it contains many examples, questions, and problems divided into three hierarchical learning skills: understanding, analyzing, and evaluating the concepts. The author attempts to break down the boundaries between biology, chemistry, physics, engineering, and ethics. He accomplishes this by co-mingling the vocabulary and concepts of these disciplines around bio-applications. Copiously illustrated, this new text leans heavily towards biological and biomedical applications and includes a comprehensive chapter on ethics.
This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give readers a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. This is a useful handbook for frontline researchers as well as a textbook for advanced students. Print ISBN: 978-981-4303-33-0 eBook ISBN: 978-981-4303-34-7 February 2012, 6 x 9, 350 pp. Suggested Price: $199.95 / £127.00
Print ISBN: 978-1-4200-8203-6 eBook ISBN: 978-1-4200-8204-3 January 2013, 7 x 10, 611 pp. Suggested Price: $89.95 / £57.99
Handbook of Safety Assessment of Nanomaterials
Mass Transport of Nanocarriers
From Toxicological Testing to Personalized Medicine
Edited by
Edited by
Bengt Fadeel Karolinska Institutet, Stockholm, Sweden Series: Pan Stanford Series on Biomedical Nanotechnology
This handbook, written by leading international experts, provides an overview of the state of the art of safety assessment of nanomaterials in context of their application in nanomedicine. The volume includes a historical perspective on the development of nanomedicine(s) and their regulation, and a personal view of the future of (nano)medicine by Patrick Hunziker, president of the European Society of Nanomedicine. The volume includes a series of chapters on organ-specific toxicities of nanomaterials, including pulmonary and cardiovascular toxicity, neurotoxicity, dermatotoxicity, and reproductive toxicity, as well as a discussion on immunotoxicity and genotoxicity.
Nanobiotechnology
Edited by
Varvara Karagkiozaki and Stergios Logothetidis
Rita Elena Serda University of Texas Health Science Center, Houston, USA
This book describes barriers from the macro to the nanoscale, starting with endothelial and mucosal barriers, and ending with cellular organelles. Experimental approaches to track nanoparticles in vitro and in vivo are presented, as well as the ability to tailor-make nanoparticles for specific functions. Several model types of nanoparticles are presented, as well the impact of particle attributes on biological transport. Print ISBN: 978-981-4364-41-6 eBook ISBN: 978-981-4364-42-3 December 2012, 6 x 9, 476 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-981-4463-36-2 January 2014, 6 x 9, 500 pp. Suggested Price: $249.95 / £159.00
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45
Textbook
Molecular Motors in Bionanotechnology Keith Firman and James Youell University of Portsmouth, UK
Nanobiotechnology
Many techniques have evolved to study and characterize molecular motors at the single-molecule level, such as the use of molecular tweezer devices for single-molecule studies. This book describes a wide range of molecular motors, from chemical to biological. It introduces readers to the concepts and benefits of each technique and looks at structural information and how this helps us to understand function. The book also examines how some of these motors are being used or may be used in the future as part of a synthetic biology approach to building devices and sensors. Print ISBN: 978-981-4267-02-1 eBook ISBN: 978-1-4665-1719-6 March 2013, 6 x 9, 212 pp. Suggested Price: $149.95 / £95.00
Edited by
Yubing Xie University at Albany, College of Nanoscale Science and Engineering, New York, USA
Offering a uniquely thorough overview of nanobiotechnology and its place in today’s advancements in applied science, this comprehensive survey combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science, bioanalysis, and bioenergy to address the full scope of current and future developments. World class experts discuss the role of nanobiotechnology in bioanalysis, biomolecular nanotechnology, biosensors, and the use of nanotechnology in biofuels. Extensive references within each chapter facilitate further investigation into the field. Print ISBN: 978-1-4398-3869-3 eBook ISBN: 978-1-4398-3870-9 November 2012, 7 x 10, 692 pp. Suggested Price: $179.95 / £113.00
Multiporphyrin Arrays
NanoCellBiology
Fundamentals and Applications Edited by
Multimodal Imaging in Biology & Medicine
Dongho Kim
Edited by
Institute for NanoBio Molecular Assemblies, Seoul, South Korea
Bhanu P. Jena Douglas J. Taatjes
This book provides a comprehensive review of the fundamentals and applications of multiporphyrin arrays ranging from basic spectroscopic features to a wide range of promising applications such as molecular wires, switches, sensors, artificial photosynthetic devices, and dye-sensitized solar cells based on a variety of multiporphyrin architectures using covalent and/or noncovalent molecular assemblies. Particularly, it focuses on energy and electron transfer processes occurring in multiporphyrin arrays in various environments such as singlemolecule level, composite materials, LB films, and solid surface to provide better understanding of photofunctional molecular architectures.
46
The Nanobiotechnology Handbook
This book provides a comprehensive understanding of the discovery of a new cellular structure the “porosome,” which is the universal secretory machinery in cells; the protein assembly, biomineralization, and biomolecular interactions; the molecular evolution of protein structure; the use of magnetic nanoparticles for transformative application in medicine and therapy, and the new and novel imaging approach of electrical impedance spectroscopy in biology. It be used for college courses in nanomedicine, nano cell biology, advanced nanotechnology, and biotechnology at the undergraduate and graduate level.
Print ISBN: 978-981-4316-60-6 eBook ISBN: 978-981-4364-28-7 January 2012, 6 x 9, 828 pp. Suggested Price: $249.95 / £159.00
Print ISBN: 978-981-4411-79-0 December 2013, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00
Nanoantenna
Nanofabrication Handbook
Plasmon-Enhanced Spectroscopies for Biotechnological Applications
Edited by
Stefano Cabrini
Edited by
Lawrence Berkeley National Laboratory, Berkeley, California, USA
Marc Lamy de la Chapelle
Satoshi Kawata
Université Paris 13, Bobigny, France
Annemarie Pucci
Osaka University, Japan
This book concentrates on the various fields related to the development of a nanobiosensor and presents the latest information from renowned experts. It focuses on the enhanced spectroscopy, including SERS, SEIRA/SEIRS, and nearfield optics, and the related physical processes (optical properties of metallic nanoparticles, plasmon resonance, field enhancement, etc.). Some applications in the biological and medical field are presented to show the potential of such techniques as sensors if combined with functionalization.
This comprehensive handbook presents a unique collection of new and important approaches to nanofabrication, from electron beam lithography, focused ion beam, and optical lithography to two-photon lithography, self-assembly, and plasmonic nanolithography. Contributors from leading research facilities and academic institutions offer hands-on instructions and examples and pave the way for future research. The practical information provided in the book gives readers a foundation to enter the complex world of nanofabrication and helps them to select the proper fabricating technique for their experiments.
Print ISBN: 978-981-4303-61-3 eBook ISBN: 978-981-4303-62-0 January 2013, 6 x 9, 452 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4200-9052-9 eBook ISBN: 978-1-4200-9053-6 February 2012, 8-1/2 x 11, 546 pp. Suggested Price: $135.95 / £86.00
Kirchhoff-Institut für Physik, Heidelberg, Germany
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Edited by
Martin Pumera
Nanomedicine and Drug Delivery Edited by
Mathew Sebastian, Neethu Ninan, and A. K. Haghi
Nanyang Technological University, Singapore
Series: Advances in Nanoscience and Nanotechnology
Nanotechnology brings new possibilities for the development of sensors, biosensors, and novel electrochemical bioassays. Nanoscale materials have been extensively used in a wide variety of configurations—as electrode surfaces to promote electrochemical reaction, as “wires” to enzymes connecting their redox centers to electrode surface, as nanobarcodes for biomolecules, or as tags to amplify the signal of a biorecognition event. Nanomaterial-based electrochemical sensors have been used in many areas, including cancer diagnostics and the detection of infectious organisms. This book reviews important achievements in the field of nanomaterial-based electrochemical sensors and biosensors.
This forward-looking book focuses on the recent advances in nanomedicine and drug delivery. It outlines the extraordinary new tools that have become available in nanomedicine and presents an integrated set of perspectives that describe where we are now and where we should be headed to put nanomedicine devices into applications as quickly as possible, while also considering the possible dangers of nanomedicine.
Print ISBN: 978-981-4364-90-4 December 2013, 6 x 9, 250 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-926895-17-8 eBook ISBN: 978-1-4665-6007-9 July 2012, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $149.95 / £95.00
Nanomedicine
Nanoparticles
A Soft Matter Perspective
Drug Inhalation Therapy
Edited by
Edited by
Dipanjan Pan
Akira Tsuda
This book provides a broad introduction to soft matters for nanomedicinal applications, with a deeper discussion of the individual modalities for molecular imaging. It includes a general introduction to the opportunities provided by this technology in chemistry, materials, biology, and nanomedicine. It is designed and written with the perspective that anyone, with or without previous knowledge of nanotechnology, would benefit. Print ISBN: 978-1-4665-7282-9 April 2014, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $129.95 / £82.00
Harvard University, Cambridge, Massachusetts, USA
Peter Gehr University of Bern, Switzerland
Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Therefore, nanoparticles, compared to larger micrometer particles, are considered to behave differently when they interact with cells. This book describes the sequence of events that airborne nanoparticles encounter in the lungs when they move from air to the bloodstream. This includes deposition, events occurring on the alveolar surface (including retention and clearance, and interaction with surfactant and with alveolar lining fluid), crossing the air-blood tissue barrier, and finally getting into the bloodstream. Print ISBN: 978-1-4398-9279-4 June 2014, 6-1/8 x 9-1/4, 500 pp. Suggested Price: $179.95 / £114.00
Nanomedicine and Cancer Therapies
Nanoparticles in Humans
Edited by
Edited by
Mathew Sebastian, Neethu Ninan, and Eldho Elias
Lev S. Ruzer
Nanotechnology has the power to radically change the way cancer is diagnosed, imaged, and treated. The holistic approach to cancer involves noninvasive procedures that emphasize restoring the health of human energy fields. Presenting a wealth of information and research about the most potent cancer healing therapies, this forward-thinking book explores how nanomedicine, holistic medicine, and other cancer therapies play important roles in treatment of this disease. Topics include nanobiotechnology for antibacterial therapy and diagnosis, mitochondrial dysfunction and cancer, antioxidants and combinatorial therapies, and optical and mechanical investigations of nanostructures for biomolecular detection. Print ISBN: 978-1-926895-18-5 eBook ISBN: 978-1-4665-6008-6 July 2012, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $149.95 / £95.00
Experiments, Methods and Strategies Lawrence Berkeley National Laboratory, California, USA
Series: Advances in Nanoscience and Nanotechnology
Nanobiotechnology
Nanomaterials for Electrochemical Sensing and Biosensing
This book uniquely uses graphs and diagrams to build an understanding of the methods for measuring the surface area and local deposition of nanoparticles in lungs and the effectiveness of respirators in case of nanoparticle exposure. It begins by discussing radon and health. It reviews spectrometry and measurement of nanoparticle activity in the lungs. It describes the assessment of nanoparticle surface area by measuring unattached fraction of radon progeny, explores the unattached radon progeny as an experimental tool, and addresses the impact of dosage on health effects. Print ISBN: 978-981-4463-16-4 May 2014, 6 x 9, 250 pp. Suggested Price: $149.95 / £95.00
For more information and a complete list of titles, visit us at www.crcpress.com
47
Nanopatterning and Nanoscale Devices for Biological Applications
Nanostructures in Biological Systems
Edited by
Aleš Iglic, Damjana Drobne, and Veronika Kralj-Iglic
Krzysztof Iniewski CMOS Emerging Technologies Research Inc., Vancouver, British Columbia, Canada
Seila Selimovic Harvard Medical School, Cambridge, Massachusetts, USA Series: Devices, Circuits, and Systems
Nanobiotechnology
Nano- and microscale techniques and devices have had a steadily growing influence on research in life sciences and bioengineering, leading to the emergence of microfluidics for biological applications and nanobioengineering as a new research focus. This book is designed to serve as an introduction to the field for graduate students in biological engineering and related disciplines. The chapters include plenty of detail to awaken the interest of any reader, yet are written with the beginning researcher in mind and provide sufficient background information. It is also suitable for advanced researchers, as a review of the latest published studies.
The book surveys recent theoretical and experimental results on nanostructures in biological systems and explores possible applications. A unifying approach starting from the single-particle energy, deriving free energy of the system and determining the equilibrium by minimizing the free energy, is applied in describing electrical and elastic phenomena. The authors present potential clinical uses of in hemostasis, inflammation, and spreading of cancer. They also cover interactions between biological membranes and inorganic nanostructures. Print ISBN: 978-981-4267-20-5 September 2013, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4665-8631-4 June 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $129.95 / £82.00
Nanotechnology Nanoscience and Nanoengineering
The Whole Story
Advances and Applications
This book communicates, in easy-to-understand language, the sometimes tough-to-understand concepts of nanotechnology, providing a comprehensive reference for technically interested/trained laymen in the general public who want to learn more about this revolutionary, high-impact field of technology. The amount and level of math used in the pedagogy of the text has been minimized to cater to a general audience. The book includes behind-the-scenes stories of Nobel-prize-winning scientists—complete with eureka moments—as well as back-of-the-envelope calculations showing the real numbers of nanotechnology. Thematic figures have been created to pique the interest and guide readers.
Edited by
Ajit D. Kelkar, Daniel J.C. Herr, and James G. Ryan
48
Theory and Applications
This book provides readers with selected recent breakthroughs in six nanotechnology platforms that exhibit high impact potential. These platforms include nanoelectronics, nanobiology, nanomedicine, nanomodeling, nanomanufacturing and related applications, and nanosafety. The chapters are designed to convey synergistic advances in understanding and application opportunities that can be achieved through an interdisciplinary approach to exploring each platform. Across each platform runs thematic threads that help to reinforce the need for a multidisciplinary approach to understanding and leveraging nanoworld phenomena. Print ISBN: 978-1-4822-3119-9 May 2014, 6-1/8 x 9-1/4, 224 pp. Suggested Price: $159.95 / £99.00
Nanostructures and Nanoconstructions Based on DNA Yuri M. Yevdokimov, V.I. Salyanov, and S.G. Skuridin
Ben Rogers, Jesse Adams, and Sumita Pennathur
Print ISBN: 978-1-4398-9780-5 eBook ISBN: 978-1-4665-0210-9 March 2013, 6-1/8 x 9-1/4, 395 pp. Suggested Price: $69.95 / £44.99
Nanotechnology and Human Health Edited by
Ineke Malsch Malsch Techno Valuation, Utrecht, The Netherlands
Series: Liquid Crystals Book Series
Claude Emond
This reference covers information currently available on the specific properties of metallic nanoparticles and compares their properties with those related to nano-objects formed by biological molecules. Containing more DNA physics and molecular biology than other published books, it also presents the details of formation and physicochemical peculiarities of DNA nanostructures and DNA-based nanoconstructions. The authors discuss how nucleic acid molecules and their complexes with chemical and biologically active compounds are of great interest in the development of various nanoscale systems and devices of practical importance.
Addressing medium- and long-term expectations for human health, this book reviews current scientific and technical developments in nanotechnology for biomedical, agrofood, and environmental applications. This collection of perspectives on the ethical, legal, and societal implications of bionanotechnology provides unique insight into contemporary technological developments. Readers with a technical background will benefit from the overview of the state-of-the-art research in the field, while readers with a social science background will benefit from the discussion of realistic prospects of nanotechnology. The text also includes a glossary as well as extensive end-of-chapter references.
Print ISBN: 978-1-4665-0569-8 eBook ISBN: 978-1-4665-0570-4 June 2012, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $146.95 / £93.00
Print ISBN: 978-0-8493-8144-7 eBook ISBN: 978-0-8493-8145-4 August 2013, 6-1/8 x 9-1/4, 376 pp. Suggested Price: $139.95 / £89.00
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Responsible Nanobiotechnology
Understanding Biophotonics
Philosophy and Ethics Armin Grunwald
Fundamentals, Advances and Applications
Karlsruhe Institute of Technology, Germany
Edited by
Print ISBN: 978-981-4316-80-4 eBook ISBN: 978-981-4364-33-1 October 2012, 6 x 9, 400 pp. Suggested Price: $149.95 / £95.00
Kevin Tsia Major advancements in biophotonics have successfully permeated biochemistry and cell/molecular biology as well as numerous preclinical applications. This book presents the fundamentals of optics and biophotonics to newcomers who are interested in this multidisciplinary research field. With contributions from leading experts, the text highlights current advancements in preclinical diagnostics using optical microscopy and spectroscopy, including multiphoton microscopy, nanoscopy, and endomicroscopy. The book also introduces a number of emerging techniques and toolsets for biophotonics applications, such as nanoplasmonics, microresonators for molecular detection, and subcellular optical nanosurgery. Print ISBN: 978-981-4411-77-6 January 2014, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00
RNA Nanotechnology and Therapeutics
Biology of Oral Cancer
Edited by
Prakash S. Bisen, Zakir Khan, and Saurabh Bundela
Peixuan Guo and Farzin Haque Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world’s foremost experts in nanomedicine, this comprehensive, state-ofthe-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. In addition, the text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, RNA chemistry for nanoparticle synthesis, and conjugation and labeling. Print ISBN: 978-1-4665-0566-7 eBook ISBN: 978-1-4665-0583-4 July 2013, 7 x 10, 611 pp. Suggested Price: $179.95 / £114.00
Key Apoptotic Regulators
Cancer is a class of disease or disorders characterized by uncontrolled division of cells and the ability of these cells to invade other tissues. One new approach in dealing with cancer is through apoptotic regulators, which is the process of controlling cell growth by abnormally prolonging cell survival, facilitating the accumulation of transforming mutations and promoting resistance. This book uses oral cancers as the specific means to demonstrate this technique with this particular type of cancer, which is quite prevalent in India and other parts of Asia. Print ISBN: 978-1-4665-7558-5 eBook ISBN: 978-1-4665-7562-2 July 2013, 6-1/8 x 9-1/4, 292 pp. Suggested Price: $139.95 / £89.00
49
Self-Assembled Peptide Nanostructures
Handbook of Therapeutic Biomarkers in Cancer
Advances and Applications in Nanobiotechnology
Edited by
Edited by
Sherry X. Yang National Cancer Institute, Bethesda, Maryland, USA
Janet E. Dancey
Jaime Castillo, Luigi Sasso, and Winnie Edith Svendsen
Ontario Institute for Cancer Research, Toronto, Canada
This book introduces readers to the theory and mechanisms of peptide self-assembly processes. The authors present the more common peptide self-assembled building blocks and discuss how researchers from different fields can apply self-assembling principles to bionanotechnology applications. The advantages and challenges are mentioned together with examples that reflect the state of the art of the use of self-assembled peptide building blocks in nanotechnology. Print ISBN: 978-981-4316-94-1 eBook ISBN: 978-981-4364-47-8 November 2012, 6 x 9, 324 pp. Suggested Price: $149.95 / £95.00
Nanobiotechnology / Cell Biology
This book comprehensively reviews the considerations of nanotechnology elaborated in philosophy, ethics, and the social sciences and systematizes and develops them further. It focuses on the issues of ethical responsibility regarding chances and risks of nanotechnology and its possible applications in the fields of synthetic nanoparticles, synthetic biology, animal enhancement, and human enhancement. The book has been, thus, put in the context of the keywords “responsible innovation” and “reflective sciences,” which have been central concepts in the debates about the relationship between science and society for the last few years.
In this volume a team of internationally recognized experts provide an in-depth description of therapeutic biomarkers across a broad area of cancer research and oncology. With a wealth of information to specific therapies, each chapter focuses on a class of targeted chemotherapy agents. The book describes established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions. This volume is an essential handbook for health professionals and scientists researching current applicable biomarkers in oncology. Print ISBN: 978-981-4364-65-2 eBook ISBN: 978-981-4364-66-9 June 2013, 6 x 9, 518 pp. Suggested Price: $179.95 / £114.00
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Cell Biology / Immunology / Lab Animals 50
Trends in Biophysics
Neuroviral Infections
From Cell Dynamics Toward Multicellular Growth Phenomena
Two Volume Set
Edited by
Sunit K. Singh
Pavel Kraikivski
Centre for Cellular and Molecular Biology, Hyderabad, India
This book covers a wide scope of biological approaches to such biological phenomena as cell division, motility, collective cell behavior, multicellular structures, morphogenesis, and tumor development. It presents recent advances in biophysical studies of living cells and describes how a combination of quantitative live cell observations, detailed biochemical and biophysical data, and mathematical modeling are capable of answering many important biological questions to achieve a more complete understanding of such complex phenomena.
Daniel Ruzek
Print ISBN: 978-1-926895-36-9 eBook ISBN: 978-1-4665-8410-5 April 2013, 6-1/8 x 9-1/4, 294 pp. Suggested Price: $129.95 / £82.00
Edited by
Biology Centre ASCR- Institute of Parasitology, Ceske Budejovice, Czech Republic
Neurotropic viruses—viral infections of the central nervous system—are often lethal. Understanding these diseases involves understanding the interaction between the nervous system and the immune system. This book provides indepth information about each individual virus, the disease it causes, and the mechanisms of spread of the disease. Addressing both clinical and basic science aspects, this two-volume set covers such diseases as polio, measles, rabies, herpes, West Nile, Japanese encephalitis, and varicella-zoster. The authors also include detailed discussions of molecular pathogenesis and host-pathogen immune interaction as well as disease detection, treatment, and prevention. Print ISBN: 978-1-4398-6852-2 February 2013, 6-1/8 x 9-1/4, 909 pp. Suggested Price: $329.95 / £210.00
Connexin Cell Communication Channels
Also available as individual volumes
Roles in the Immune System and Immunopathology
Neuroviral Infections
Edited by
General Principles and DNA Viruses
Ernesto Oviedo-Orta, Brenda R. Kwak, and William Howard Evans
Print ISBN: 978-1-4665-6719-1 eBook ISBN: 978-1-4665-6722-1 February 2013, 6-1/8 x 9-1/4, 390 pp. Suggested Price: $159.95 / £99.00
Plasma membrane-associated channels known as gap junctions, along with their protein building blocks—connexins—have an important functional role in a range of immunological processes. This volume assembles and synthesizes four decades of the most important research carried out in this field. The contributors focus on the latest progress made on translating the knowledge gained for specific treatment modalities. Topics include approaches for reducing scarring and cardiac arrhythmia, combating inflammation in the central nervous system, and enhancing epithelial tissue repair. The book informs and updates specialists, clinical practitioners, and those studying the potential for commercial applications.
Neuroviral Infections RNA Viruses and Retroviruses Print ISBN: 978-1-4665-6720-7 eBook ISBN: 978-1-4665-6723-8 February 2013, 6-1/8 x 9-1/4, 519 pp. Suggested Price: $159.95 / £99.00
Print ISBN: 978-1-4398-6257-5 eBook ISBN: 978-1-4398-6258-2 March 2013, 6-1/8 x 9-1/4, 380 pp. Suggested Price: $149.95 / £99.00
Flow Cyclometry A Practical Guide Edited by
Albert D. Donnenberg Hillman Cancer Center, Pittsburgh, Pennsylvania, USA
Fiona Elizabeth Craig University of Pittsburgh, Pennsylvania, USA
Highlighting one of the most powerful analytic and preparative techniques in cell biology, this book compiles six lectures by recognized experts in the field. It covers the design of a flow cytometry experiment, rare event analysis, functional assays, assays of cell proliferation, solid tissue experiments, and imaging in flow cytometry. Written in an easy-to-read style and accompanied by expert commentary, each topic is chosen and discussed with regard to its relevance in the field, importance in biomedical research, and frequency of misuse in scientific literature. Print ISBN: 978-1-4398-0034-8 May 2014, 6-1/8 x 9-1/4, 512 pp. Suggested Price: $149.95 / £95.00
Biodefense Research Methodology and Animal Models Second Edition Edited by
James R. Swearengen National Biodefense Analysis and Countermeasures Center, Frederick, Maryland, USA
Since the publication of the first edition of this volume, significant advances have been made in animal model development for biological research and the ramifications of the FDA’s Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, this volume spans the spectrum of coverage from basic research to advanced development of medical countermeasures. Topics discussed include a history of biological agents as weapons, concepts and strategies involved in biowarfare and bioterrorism, animal models in biodefense research, and infectious disease aerobiology. The book also presents studies involving a range of specific diseases and toxins. Print ISBN: 978-1-4398-3632-3 eBook ISBN: 978-1-4398-3633-0 February 2012, 6-1/8 x 9-1/4, 415 pp. Suggested Price: $135.95 / £86.00
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Critical Care Management for Laboratory Mice and Rats
Infectious Diseases and Pathology of Reptiles
F. Claire Hankenson
Color Atlas and Text
Series: Laboratory Animal Pocket Reference
Due to the unique nature of developing animal models of human diseases and disorders, many of the standard approaches to veterinary care cannot be applied to the laboratory animal. The first comprehensive resource for common treatment approaches to emergencies and critical cases in laboratory animal medicine, this book shows readers how to administer patient-tailored care based upon knowledge of the characteristics of the animal species, the human disease model of research interest, and practical, economic, and regulatory factors. Print ISBN: 978-0-8493-2499-4 October 2013, 6-1/8 x 9-1/4, 271 pp., Soft Cover Suggested Price: $59.95 / £38.99
Edited by
Elliott Jacobson University of Florida, College of Veterinary Medicine, Gainesville, USA
Featuring 1,200 high-quality, color photos of normal anatomy and histology, as well as gross, light, and electron microscopic images of pathogens and diseases, this exceptionally comprehensive atlas provides definitive information on every known infectious disease affecting reptiles. Beginning with a thorough review of reptile biology, anatomy, and histology, leading authorities address specific topics such as immunology, circulating inflammatory cells, necropsy techniques, pathogen identification and isolation, molecular diagnosis, and serodiagnostics. The atlas also catalogs specific pathologies due to viruses, bacteria, fungi, and parasites. Print ISBN: 978-0-8493-2321-8 eBook ISBN: 978-1-4200-0403-8 April 2007, 8-1/2 x 11, 736 pp. Suggested Price: $210.00 / £134.00
Handbook of Laboratory Animal Science
Non-Clinical Vascular Infusion Technology
Volume III, Third Edition Animal Models
Two Volume Set Science and Techniques
Edited by
Edited by
Jann Hau
Owen P. Green
University of Copenhagen & Rigshospitalet, Denmark
LeVerts Ltd., Peterborough, UK
Steven J. Schapiro
Guy Healing
The University of Texas MD Anderson Cancer Center, Bastrop, USA
AstraZeneca, Cheshire, UK
Building upon the success of the bestselling Handbook of Laboratory Animal Science and complementing Volumes I and II of the third edition, this new volume completes the task of providing a comprehensive overview of animal models in all biomedical disciplines. The book covers most of the important lab animal science bases. As with Volume II, the book focuses on the pertinent comparative aspects of the many different contexts in which animals are used as well as on the spontaneous genetic mutants and the genetically modified animal models available within different research areas.
This two-volume set contains The Techniques of Non-Clinical Vascular Infusion Technology, Second Edition and The Science of Non-Clinical Vascular Infusion Technology. The first volume provides complete instructions for a wide range of infusion techniques delivered to multiple species. With sections devoted to rats, mice, rabbits, dogs, minipigs, nonhuman primates, and juvenile animals, this thorough text gives step-by-step instructions for the use of a variety of techniques and equipment. The second volume brings together the knowledge underlying practices from around the world to help refine the procedures and enhance the understanding of infusion technology.
Print ISBN: 978-1-4665-5512-9 January 2014, 7 x 10, 320 pp. Suggested Price: $119.95 / £76.99
Print ISBN: 978-1-4398-7440-0 January 2014, 6-1/8 x 9-1/4, 520 pp. Suggested Price: $179.95 / £114.00
Also available as individual volumes
The IACUC Handbook Second Edition Edited by
Jerald Silverman, Mark A. Suckow, and Sreekant Murthy Since its establishment by USDA regulation in the 1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premiere US instrument for animal welfare supervision. The IACUC Handbook provides a foundation for those attempting to understand and implement the various responsibilities of this committee. This new edition features comprehensive updates for all pertinent federal laws, regulations, and policies. It incorporates revised suggestions on best-practice compliance from experienced professionals. With concise, easy-to-find information, it remains the reference of choice for researchers and professionals.
Non-Clinical Vascular Infusion Technology, Volume I: The Science Print ISBN: 978-1-4398-7449-3 eBook ISBN: 978-1-4398-7450-9 September 2013, 6-1/8 x 9-1/4, 215 pp. Suggested Price: $79.95 / £49.99
Non-Clinical Vascular Infusion Technology, Volume II: The Techniques Print ISBN: 978-1-4398-7445-5 December 2013, 6-1/8 x 9-1/4, 344 pp. Suggested Price: $119.95 / £76.99
Print ISBN: 978-0-8493-4010-9 eBook ISBN: 978-1-4665-1168-2 October 2006, 7 x 10, 680 pp. Suggested Price: $93.95 / £59.99
For more information and a complete list of titles, visit us at www.crcpress.com
Lab Animals
University of Pennsylvania, Philadelphia, USA
51
Laboratory Animal Pocket Reference Series
The Laboratory Mouse
13-Volume Set
Second Edition
Edited by
Peggy J. Danneman
Mark A. Suckow
The Jackson Laboratory, Bar Harbor, Maine, USA
The Laboratory Animal Pocket Reference Series discusses procedures that ensure laboratory animals receive the best, most humane, and most responsible care possible. The 13 volumes are compact and comb-bound to lay flat for use in the laboratory. The contents of each include important biological features, husbandry, management, veterinary care, regulatory concerns, and commonly used and new procedures, as well as an invaluable list of suppliers. Each book in the series can be purchased individually or as part of the set.
University of Notre Dame, Indiana, USA
Print ISBN: 978-0-8493-2560-1 March 2000, 7-1/2 x 9-1/4, 167 pp. Suggested Price: $649.95 / £414.00
Lab Animals
The Laboratory Canine Garrett Field Eli Lilly and Company, Indianapolis, Indiana, USA
Todd A. Jackson Bristol-Myers Squibb, Evansville, Indiana, USA Series: Laboratory Animal Pocket Reference
Print ISBN: 978-0-8493-2893-0 October 2006, 6-1/8 x 9-1/4, 184 pp., Soft Cover Suggested Price: $59.95 / £38.99
The Laboratory Cat
Cory Brayton Johns Hopkins University, Baltimore, Maryland, USA Series: Laboratory Animal Pocket Reference
Print ISBN: 978-1-4398-5421-1 eBook ISBN: 978-1-4398-5422-8 September 2012, 6-1/8 x 9-1/4, 256 pp., Soft Cover Suggested Price: $59.95 / £38.99
The Laboratory Nonhuman Primate Jeffery D. Fortman and B. Taylor Bennett University of Illinois, Chicago, USA
Terry A. Hewett University of California, Davis, USA Series: Laboratory Animal Pocket Reference
Print ISBN: 978-0-8493-2562-5 eBook ISBN: 978-0-8493-7699-3 September 2001, 6-1/8 x 9-1/4, 288 pp., Soft Cover Suggested Price: $59.95 / £38.99
The Laboratory Rabbit Second Edition Mark A. Suckow and Valerie Schroeder
Brent J. Martin
University of Notre Dame, Indiana, USA
Medical University of Ohio, Toledo, USA
Fred A. Douglas
Series: Laboratory Animal Pocket Reference
Purdue University, West Lafayette, Indiana, USA
Print ISBN: 978-0-8493-2567-0 November 1997, 6-1/8 x 9-1/4, 160 pp., Soft Cover Suggested Price: $59.95 / £38.99
The Laboratory Ferret
52
Mark A. Suckow
C. Andrew Matchett, Rena Marr, Felipe M. Berard, Andrew G. Cawthon, and Sonya P. Swing Series: Laboratory Animal Pocket Reference
Series: Laboratory Animal Pocket Reference
Print ISBN: 978-1-4200-9105-2 eBook ISBN: 978-1-4200-9106-9 April 2010, 6-1/8 x 9-1/4, 148 pp., Soft Cover Suggested Price: $59.95 / £38.99
The Laboratory Rat Second Edition Patrick Sharp and Jason Villano
Print ISBN: 978-1-4398-6181-3 eBook ISBN: 978-1-4398-6182-0 March 2012, 6-1/8 x 9-1/4, 123 pp., Soft Cover Suggested Price: $59.95 / £38.99
Series: Laboratory Animal Pocket Reference
The Laboratory Guinea Pig, Second Edition
The Laboratory Small Ruminant
Donna J. Clemons Jennifer L. Seeman Covance Laboratories Inc., Madison, Wisconsin, USA Series: Laboratory Animal Pocket Reference
Print ISBN: 978-1-4398-3556-2 June 2011, 6-1/8 x 9-1/4, 172 pp., Soft Cover Suggested Price: $59.95 / £38.99
Print ISBN: 978-1-4398-2986-8 eBook ISBN: 978-1-4398-2987-5 December 2012, 6-1/8 x 9-1/4, 399 pp., Soft Cover Suggested Price: $59.95 / £38.99
Matthew J. Allen SUNY Health Science Center, Syracuse, New York, USA
Gary L. Borkowski Consultant, Saint Louis, Missouri, USA Series: Laboratory Animal Pocket Reference
Print ISBN: 978-0-8493-2568-7 March 1999, 6-1/8 x 9-1/4, 176 pp., Soft Cover Suggested Price: $59.95 / £38.99
The Laboratory Swine
The Laboratory Hamster and Gerbil
Second Edition
Karl J. Field
Axel K. Hansen
Bristol Myers Veterinary Sciences, Flemington, New Jersey, USA
Amber L. Sibold Consultant, East Hanover, New Jersey, USA Series: Laboratory Animal Pocket Reference
Print ISBN: 978-0-8493-2566-3 December 1998, 6-1/8 x 9-1/4, 168 pp., Soft Cover Suggested Price: $59.95 / £38.99
Peter J. A. Bollen University of Southern Denmark, Odense University of Copenhagen, Frederiksberg, Denmark
Aage K Olsen Alstrup Aarhus University Hospital, Aarhus, Denmark Series: Laboratory Animal Pocket Reference
Print ISBN: 978-1-4398-1528-1 February 2010, 6-1/8 x 9-1/4, 138 pp., Soft Cover Suggested Price: $59.95 / £38.99
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Edited by
Angela Courtney University of California, Davis, USA
An easy-to-understand pocket manual, this indispensible reference compiles key and important clinical medical information unique to the rhesus macaque and the cynomolgus macaque. The chapter authors denote specific treatments for other nonhuman primate species where applicable. Practical and user-friendly, this book mirrors the knowledge gained by completing a residency in clinical primate medicine. It provides formulary and drug dosages, special precautions, and important notations. It discusses diseases and clinical problems and outlines treatment based on current medicine and explains common procedures with full-color illustrations for quick reference. Print ISBN: 978-1-4398-6728-0 eBook ISBN: 978-1-4398-6729-7 October 2012, 6-1/8 x 9-1/4, 251 pp., Soft Cover Suggested Price: $99.95 / £63.99
Rearing Animal and Plant Pathogen Vectors Edited by
Karl Maramorosch Rutgers of Cook College, New Brunswick, New Jersey, USA
Farida Mahmood This book provides an integrated description of methods used to rear vectors of human, higher animal, and plant pathogens in the laboratory. It deals with diverse subject areas, and contains descriptions of standard, as well as highly specialized, methods used by medical, veterinary, entomology, and plant pathology experts. The text brings together the standard breeding and manipulation methods developed in America, Europe, Asia, and Africa. It describes the cultivating, handling, sterile techniques, and cell culture as well as safety measures to prevent contamination and escape of insects, ticks, nematodes, and fungal vectors.
Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix jacchus) Craig D. Hardman and Ken W. S. Ashwell University of New South Wales, Sydney, Australia
Written for international neuroscientists engaged in research of neurological disorders such as Parkinson’s disease, multiple sclerosis, and Alzheimer’s disease, as well as professionals working in laboratories conducting pharmacokinetic studies, this book is the first comprehensive stereotaxic atlas of all parts of the marmoset brain, including upto-date data on cortical areas. The atlas provides precise stereotaxic co-ordinates, functionally important chemoarchitectural information, and estimates for the numbers of neurons within important brain regions and nuclei. It also provides information for assessing the efficacy of treatments in marmoset models. Print ISBN: 978-1-4398-3778-8 eBook ISBN: 978-1-4398-3779-5 January 2012, 8-1/2 x 11, 515 pp. Suggested Price: $179.95 / £114.00
Suturing Principles and Techniques in Laboratory Animal Surgery Manual and DVD John J. Bogdanske, Scott Hubbard-Van Stelle, Margaret Rankin Riley, and Beth M. Schiffman
Lab Animals / Microbiology
Pocket Handbook of Nonhuman Primate Clinical Medicine
This color manual and accompanying DVD introduce the basic principles of, and the materials and instruments required for, suturing and wound closure on animals in a research or veterinary facility. It covers instrumentation holding and handling; needle types and applications; and suture material, packaging, and applications. It also provides in-depth coverage of various suture patterns and associated principles for proper knot tying, including step-by-step descriptions, video clips with narration, and handouts for each suture pattern. Print ISBN: 978-1-4665-5343-9 June 2013, 6-1/8 x 9-1/4, 123 pp., DVD Suggested Price: $59.95 / £38.99
Print ISBN: 978-1-4665-9821-8 January 2014, 6-1/8 x 9-1/4, 375 pp. Suggested Price: $129.95 / £82.00
53 Rodent Laparoscopy and Colonoscopy
Cancer Causing Viruses and Their Inhibitors
Szczepan Baran
Edited by
Veterinary Bioscience Institute, Harleysville, Pennsylvania, USA
Satya Prakash Gupta
Marcel Perret-Gentil Laboratory Animal Resource Center, San Antonio, Texas, USA
Intended for researchers as well as the clinical veterinarian serving pet owners in the general public, this comprehensive text represents the definitive work on rodent laparoscopy and colonoscopy. Providing step-by-step instruction, it details how to select, obtain, and care for the equipment; how to perform the procedures; and how to implement these procedures in clinical practice for financial benefit. The first and only book on the subject, it includes precise anatomical images not available anywhere else. Print ISBN: 978-1-4398-8718-9 June 2014, 6-1/8 x 9-1/4, 128 pp. Suggested Price: $69.95 / £44.99
Meerut Institute of Engineering and Technology, India
The WHO International Agency for Research on Cancer estimated that in 2002 17.8 percent of human cancers were caused by infection. Oncoviruses play a key role in the development of certain cancers by contributing to genetic changes. This book presents a plethora of research into the cancercausing viruses and their inhibitors. The contributors review different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The discoveries presented in this volume will enable researchers and clinicians to access historical and present approaches to anti-viral therapies. Print ISBN: 978-1-4665-8977-3 June 2014, 6-1/8 x 9-1/4, 488 pp. Suggested Price: $149.95 / £95.00
For more information and a complete list of titles, visit us at www.crcpress.com
Microbiology / Molecular Biology / Neuroscience 54
Human Respiratory Viral Infections
Vitamin-Binding Proteins
Edited by
Edited by
Sunit K. Singh Centre for Cellular and Molecular Biology, Hyderabad, India
Krishnamurti Dakshinamurti Shyamala Dakshinamurti
Respiratory viral infections are a major cause of morbidity and mortality. Acute respiratory infections are the most frequent illnesses of the human host. Most infections are caused by viruses and bacteria; the proportion caused by viruses is much greater. This book presents recent advances in respiratory viral research in a multidisciplinary fashion. The spectrum of discussion ranges from the basic virology of viruses infecting the respiratory system to their pathogenesis, epidemiology, immunology, and management strategies.
Minor changes in the chemical structure of vitamins can cause major differences in their binding to proteins and in their biological activity at the cell, tissue, and organ levels. Illuminating new areas of vitamin function, this book explores the interface of physiological vitamin function and pharmacological vitamin action. It summarizes the current knowledge base with regard to vitamin-binding proteins, addressing the effects that lead to both normal physiological activity and pharmacological effects with significant therapeutic potential in a wide spectrum of disease processes.
Print ISBN: 978-1-4665-8320-7 May 2014, 7 x 10, 696 pp. Suggested Price: $169.95 / £108.00
Print ISBN: 978-1-4398-8016-6 eBook ISBN: 978-1-4398-8020-3 July 2013, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $119.95 / £76.99
Functional Consequences
Amyloid Structures in Nature
Advances in Natural Medicines, Nutraceuticals and Neurocognition
Edited by
Edited by
Suzi Jarvis and Anika Mostaert
Con Kerry Kenneth Stough
The Functional Fold
Trinity College, Dublin, Ireland
Bringing together a wide variety of examples of functional amyloid in a single volume, this book explores the importance of amyloid fibrils in fungi, bacteria, algae, invertebrate, and vertebrate animals for providing environmental protection, structural integrity, and regulating biochemical processes. It highlights many of the extraordinary examples of functional amyloid found to date. It provides an exciting perspective for the study of amyloid deposits as important and useful protein structures widespread in nature. Print ISBN: 978-981-4267-40-3 eBook ISBN: 978-981-4267-62-5 August 2012, 6 x 9, 184 pp. Suggested Price: $149.95 / £95.00
Swinburne University of Technology, Hawthorne, Australia
Andrew Scholey Swinburne University, Melbourne, Australia
Great strides have been made in the field of natural medicine with respect to neurocognition. Bringing together the work of contributors from around the globe, this book examines developments related to cognitive aging; the neurocognitive effects of isolated compounds, including N-acetylcysteine and lipoic acid; the effect of supplementation with multivitamins on cognitive health; and the impact of agents that improve metabolic activity in the context of neurocognitive function. It also examines the effects of essential fatty acids, Traditional Chinese Medicine, Indian herbs, and herbal extracts on intelligence, memory, cognition, and brain functioning. Print ISBN: 978-1-4398-9360-9 eBook ISBN: 978-1-4398-9362-3 January 2013, 6-1/8 x 9-1/4, 369 pp. Suggested Price: $149.95 / £95.00
Viking DNA
Amyotrophic Lateral Sclerosis
The Wirral and West Lancashire Project
Advances and Perspectives of Neuro-Nanomedicine
Stephen E. Harding, Mark Jobling, and Turi King
Lina Machtoub
This book details a genetic survey that has taken place focusing on men from old families from Wirral and West Lancashire. These “Viking hot spots” in North West England exhibit many archaeological and historical features proving a clear Viking presence. The book explains—with the help of full color illustrations—what DNA is and how DNA methods can be used to probe both individual and population ancestry, and how information such as Henry VIII’s tax rolls can be used to help establish the volunteer base for specific regions of northern England. Print ISBN: 978-1-4665-9085-4 December 2010, 8.2 x 9.7, 166 pp., Soft Cover Suggested Price: $33.95 / £15.99
University of Innsbruck, Austria
Yu Kasugai University of Innsbruck, Austria
Recently, the implication of biocompatible nanotechnologies has set the stage for an evolutionary leap in diagnostic imaging and therapy. In this scope, the book presents a comprehensive overview of the possible causes, diagnostic criteria, and treatment assessments of amyotrophic lateral sclerosis, and presents the recent findings using innovative, highly sensitive, and novel diagnostic molecular imaging approaches. In addition, the book offers new perspectives of an innovative and recently developed approach in neuroimaging using surfaceenhanced nanoimaging microscopy, which can be a promising technique for early diagnosis and treatment assessments. Print ISBN: 978-981-4463-04-1 March 2014, 6 x 9, 250 pp. Suggested Price: $149.95 / £95.00
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Edited by
John T. Landrum Florida International University, Miami, USA
John Nolan Waterford Institute of Technology, Cork, Ireland
This book presents an up-to-date, thorough volume devoted to the chemistry, pathobiology, visual science, and medical and public health significance of the macular carotenoids. With contributions from leading experts from around the world, this book covers a range of topics, from macular anatomy and molecular genetics to retinal disease epidemiology, pathogenesis, risk factors, and carotenoid supplementation clinical trials. Advancing our understanding of how the macular carotenoids prevent vision loss, this book provides a valuable reference for researchers and clinicians involved in the treatment and prevention of retinal disease. Print ISBN: 978-1-4665-0204-8 eBook ISBN: 978-1-4665-0205-5 October 2013, 6-1/8 x 9-1/4, 272 pp. Suggested Price: $149.95 / £95.00
Computational Neuroscience Simulated Demyelinating Neuropathies and Neuronopathies Diana Ivanova Stephanova Institute of Biophysics and Biomedical Engineering, Sofia, Bulgaria
Bozhidar Dimitrov Kolev Institute for Population and Human Studies, Sofia, Bulgaria
This book covers the computer simulation of demyelinating neuropathies and neuronopathies and compares models with clinical findings. Through the approximation of nerve excitation and conduction, the authors show how the versatile structure of nerve fibers relates to different modes of focal prospects, inward and outward currents, conduction velocity, and errant transmission. They also explain how mathematical models elucidate fine distinctions between hereditary and acquired neuronal diseases, including Charcot-Marie-Tooth, chronic inflammatory demyelinating polyneuropathy, Guillain-Barre syndrome, multifocal motor neuropathy, and amyotrophic lateral sclerosis.
Endothelial Cell Plasticity in the Normal and Injured Central Nervous System Edited by
Esperanza Meléndez Herrera, Bryan V. Phillips-Farfán, and Gabriel Gutiérrez Ospina Highlighting the importance of endothelial cells as key players in the functioning of the nervous system under both normal and pathological conditions, this book reviews the newest findings in this exciting new area of investigation. The contributors demonstrate that endothelial cells are an essential and dynamic cell population in the central nervous system, with multiple and complex roles, not only in the maintenance of homeostasis, but also in the regulation of important processes. Topics discussed include neurogenesis, neural control of reproduction, aging, neurodegeneration, and tumor invasion. Print ISBN: 978-1-4665-9921-5 May 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $129.95 / £82.00
Handbook of H+-ATPases
Neuroscience
Carotenoids and Retinal Disease
Edited by
Suguru Nakamura Murray State University, Kentucky, USA
This handbook on vacuolar and plasma membrane H+-ATPases is the first to focus on an essential link between vacuolar H+-ATPase and the glycolysis metabolic pathway to understand the mechanism of diabetes and the metabolism of cancer cells. It presents recent findings on the structure and function of vacuolar H+-ATPase in glucose promoting assembly and signaling. It also describes the regulatory mechanisms of vacuolar H+-ATPase in yeast cells, neural stem cells, kidney cells, cancer cells, and under diabetic conditions. Print ISBN: 978-981-4411-91-2 February 2014, 6 x 9, 350 pp. Suggested Price: $199.95 / £127.00
Print ISBN: 978-1-4665-7832-6 eBook ISBN: 978-1-4665-7836-4 January 2013, 6-1/8 x 9-1/4, 148 pp. Suggested Price: $69.95 / £44.99
55 Humanoid Robotics and Neuroscience
EEG/ERP Analysis
Science, Engineering and Society
Methods and Applications
Edited by
Edited by
Gordon Cheng
Nidal Kamel Aamir Saeed Malik
Series: Frontiers in Neuroengineering Series
ATR Computational Neuroscience Labs, Saraku-gun, Kyoto, Japan
Universiti Teknologi Petronas, Malaysia
This book covers EEG/ERP processing and analysis and their various applications. It explains the different techniques used for preprocessing the EEG/ERP data for artifacts removal and the advanced techniques used for signal enhancement, source localization, data fusion, classification, and quantitative EEG. It also demonstrates successful clinical applications of EEG/ERP in areas such as epilepsy, brain injury, brain source localization, psychiatry, BCI, cognitive distraction, sleep deprivation, and others. The book gives clinicians an understanding of technical issues and theoretical approaches involved in EEG/ERP, and engineers an understanding of clinical applications.
With contributions from prominent scientists, this volume presents a scientific understanding of humans with a view toward developing better-engineered systems and machines for society. It covers dexterous robotic hand control, humanoid vision and locomotion, motor control and learning of motor skills, and cognitive aspects of the humanoid robot. The book also discusses the impact of robotic systems and devices on society as a whole. Print ISBN: 978-1-4200-9366-7 March 2014, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $99.95 / £63.99
Print ISBN: 978-1-4822-2469-6 June 2014, 6-1/8 x 9-1/4, 425 pp. Suggested Price: $159.95 / £99.00 For more information and a complete list of titles, visit us at www.crcpress.com
Itch
Neuroadaptive Systems
Mechanisms and Treatment
Theory and Applications
Edited by
Edited by
Earl E. Carstens
Magdalena Fafrowicz, Tadeusz Marek, Waldemar Karwowski, and Dylan Schmorrow
University of California, Davis, USA
Tasuku Akiyama Series: Frontiers in Neuroscience, 56
Neuroscience
Written by leading, internationally-known scholars in itch research and treatment, this volume presents the most current update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cell lymphomas, and systemic diseases such as kidney and liver disease and cancer. The book is designed for basic researchers, clinicians who study and treat itch, pharmaceutical companies interested in developing itch treatments, and anyone else interested in learning about itch. Print ISBN: 978-1-4665-0543-8 February 2014, 6-1/8 x 9-1/4, 418 pp. Suggested Price: $159.95 / £99.00
Print ISBN: 978-1-4398-5745-8 eBook ISBN: 978-1-4398-5799-1 October 2012, 7 x 10, 410 pp. Suggested Price: $135.95 / £86.00
Methods in Brain Connectivity Inference through Multivariates Time Series Analysis
The Neurobiological Basis of Suicide
Edited by
Koichi Sameshima University of Sao Paulo, Brazil
Luiz Antonio Baccala University Sao Paulo, Brazil Series: Frontiers in Neuroengineering Series
56
With contributions from international professionals and researchers, this book is one of the first texts to address the emerging field of neuroadaptive systems and presents the state-of-the-art developments in the field. It discusses neuroscience and human factors, as well as brain activity measurement. Topics covered include operator functional state (OFS) and neuroadaptive systems; psychological constructs versus neuronal mechanisms; object recognition versus object-directed grasping; mental fatigue, sleeplessness, and neural mechanisms of control; and attentional network and error related negativity associated with sleep deprivation.
Time series analysis approaches offer information into how brain areas effectively interact. Written by leading international authors, this book addresses the use of time series data in brain connectivity interference studies in clinical, behavioral, and experimental neurosciences. The text incorporates multidisciplinary work in applied mathematics, statistics, and animal and human experiments at the forefront of the field. Each contributor provides codes and data examples to back up their methodological descriptions, providing readers with hands-on experience with each proposed method and an appreciation of their merits and limitations. Print ISBN: 978-1-4398-4572-1 February 2014, 6-1/8 x 9-1/4, 280 pp. Suggested Price: $159.95 / £99.00
Multiple Sclerosis Rehabilitation
Edited by
Yogesh Dwivedi University of Illinois at Chicago, USA Series: Frontiers in Neuroscience
Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of less clinical value. With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding the suicide pathophysiology. This volume discusses how and why neurobiological factors are crucial in understanding the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications. Print ISBN: 978-1-4398-3881-5 eBook ISBN: 978-1-4398-3882-2 June 2012, 6-1/8 x 9-1/4, 482 pp. Suggested Price: $149.95 / £95.00
From Impairment to Participation
Neurobiology of Body Fluid Homeostasis
Edited by
Transduction and Integration
Marcia Finlayson
Edited by
Queen’s University, Kingston, Ontario, Canada Series: Rehabilitation Science in Practice Series
This comprehensive resource guides health and rehabilitation practitioners as they engage in the rehabilitation process with people with multiple sclerosis (MS). The first section offers an overview of MS basics, and the next two describe MS rehabilitation to manage impairments and enhance activity and participation. The final section discusses contextual factors that may influence MS rehabilitation efforts. The text provides a broad-based perspective on the disease, describes how it influences everyday life, and suggests strategies that can be employed by rehabilitation practitioners to enable people with MS to fully engage in everyday life. Print ISBN: 978-1-4398-2884-7 eBook ISBN: 978-1-4398-2885-4 August 2012, 7 x 10, 603 pp. Suggested Price: $159.95 / £100.00
Laurival Antonio De Luca Jr., Jose Vanderlei Menani, and Alan Kim Johnson Series: Frontiers in Neuroscience
Filled with rich examples of integrative neurobiology and regulatory physiology, this volume is drawn from the proceedings at the Body-Fluid Homeostasis: Transduction and Integration symposium held in Brazil in 2011. It provides updated research using human and animal models for the control of bodily fluids, thirst, and salt appetite. It explores neural and endocrine control of body fluid balance, arterial pressure, thermoregulation, and ingestive behavior. The contributors discuss recent developments in molecular genetics, cell biology, and behavioral plasticity, and review key aspects of brain serotonin and steroid and peptide control of fluid consumption and arterial pressure. Print ISBN: 978-1-4665-0693-0 eBook ISBN: 978-1-4665-0696-1 October 2013, 6-1/8 x 9-1/4, 336 pp. Suggested Price: $139.95 / £89.00
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Neurobiology of Chemical Communication Edited by
Carla Mucignat-Caretta
Neuropeptides in Neuroprotection and Neuroregeneration Edited by
University of Padova, Italy
Fred Nyberg
Series: Frontiers in Neuroscience
University of Uppsala, Sweden
Print ISBN: 978-1-4665-5341-5 February 2014, 6-1/8 x 9-1/4, 592 pp. Suggested Price: $149.95 / £95.00
Neuromorphic Olfaction Edited by
With contributions from a stellar panel of experts, this book discusses neuropeptides and their role in neurodegeneration and neuroprotection. The contributors describe important features of the endogenous neuropeptide systems that relate to their formation, receptor signaling, and inactivation. The book includes topics of enormous interest in the field with chapters focused on design and development of peptide-like drugs, peptidomimetics, and mechanisms of peptide transport over biological barriers, oxidative stress, and cognitive enhancement. Print ISBN: 978-1-4398-3062-8 eBook ISBN: 978-1-4398-3063-5 June 2012, 6-1/8 x 9-1/4, 319 pp. Suggested Price: $159.95 / £100.00
Neurotechnology Premises, Potential, and Problems
Neuroscience
The release of pheromones is one of various forms of nonverbal communication many animals use to transmit messages to other members of the same species. Their complex molecular structure allows these chemical messages to contain a great deal of often very specific information. This book provides an overview of recent findings in the field of pheromones and chemical signals in vertebrate and invertebrate species. It includes chapters on how chemical signals work on different species and covers non-mammalian species and mammalian pheremones in general and in particular species.
Edited by
Krishna C. Persaud
James Giordano
The University of Manchester, UK
Santiago Marco and Agustin Gutierrez-Galvez University of Barcelona and Institute for Bioengineering of Catalonia, Spain Series: Frontiers in Neuroengineering Series
Center for Neurotechnology Studies, Potomac Institute for Policy Studies, Arlington, Virginia, USA and Human Science Center, Ludwig-Maximilians University, Munich, Germany Series: Advances in Neurotechnology
With biological components of chemical sensing systems becoming well understood in terms of their structure and function, it is now possible to consider biomimetic models of olfaction and how they may be translated into functional engineering devices. This book presents an innovative interdisciplinary biomimetic approach to olfaction, addressing biology, hardware, software, and sensors. The text explores contributions to the realization of novel chemical sensing systems inspired by biological pathways and describes cuttingedge research on engineering aspects of olfaction, odor coding of neurons, chemical sensor arrays, and biologically modeled sensor robots.
New technologies that allow us to investigate mechanisms and functions of the brain have shown considerable promise in treating brain disease and injury. These emerging technologies also provide a means to assess and manipulate human consciousness, cognitions, emotions, and behaviors, bringing with them the potential to transform society. This volume explores the technical, moral, legal, and sociopolitical issues that arise in and from today’s applications of neuroscience and technology and discusses their implications for the future. Topics addressed include neurotechnology in education, neuroimaging and tissue implantation technology neuroprostheses, cyborg technology, and more.
Print ISBN: 978-1-4398-7171-3 eBook ISBN: 978-1-4398-7172-0 April 2013, 6-1/8 x 9-1/4, 238 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4398-2586-0 eBook ISBN: 978-1-4398-2628-7 April 2012, 6-1/8 x 9-1/4, 354 pp. Suggested Price: $119.95 / £77.00
Neurons and the DHA Principle
Neurotechnology in National Security and Defense
Raymond C. Valentine University of California at Davis, USA Professor Emeritus, UC Davis and Visiting Scholar, University of California, Santa Barbara, USA
David L. Valentine University of California, Santa Barbara, USA
In Alzheimer’s disease and other neurodegenerative disorders, DHA-enriched membranes of neurons become dysfunctional and energetically wasteful, triggering premature death of neurons. Recent discoveries have highlighted the role of omega-3 fatty acid DHA in brain health and degeneration as well as the molecular biology of this fatty acid in neurons. This text explores this process and proposes a new model for understanding the basis of these diseases. Using examples from the world of animal cells, the book illustrates how DHA acts both as an essential building block of neurons while also leading to their demise. Print ISBN: 978-1-4398-7486-8 eBook ISBN: 978-1-4398-7487-5 October 2012, 6-1/8 x 9-1/4, 287 pp. Suggested Price: $169.95 / £100.00
Practical Considerations, Neuroethical Concerns Edited by
James Giordano Center for Neurotechnology Studies, Potomac Institute for Policy Studies, Arlington, Virginia, USA and Human Science Center, Ludwig-Maximilians University, Munich, Germany Series: Advances in Neurotechnology
While neurotechnology exploration has been underway for several years, public debate on these issues is just beginning. National policy must address the ethical, legal, and social issues that arise from this research and its applications in humans. This book examines emerging national-level medical research with extraordinary implications across medicine, national security, and defense. It will help readers to gain a foundation of knowledge on all sides of this topic, so that they may begin to address the difficult challenges that may arise regarding applications of neurotechnology. Print ISBN: 978-1-4822-2833-5 April 2014, 6-1/8 x 9-1/4, 224 pp., Soft Cover Suggested Price: $69.95 / £44.99
For more information and a complete list of titles, visit us at www.crcpress.com
57
Parkinson’s Disease
Spike Timing
Second Edition
Mechanisms and Function
Edited by
Edited by
Ronald F. Pfeiffer, Zbigniew K. Wszolek, and Manuchair Ebadi
Patricia M. DiLorenzo
Neuroscience
In recent years, considerable advances have been made in our knowledge and understanding of Parkinson’s disease (PD). In particular, there has been an explosion of information regarding genetic contributions to the etiology of PD and an increased awareness of the importance of the non-motor features of the disease. Theories regarding the pathogenesis and pathophysiology of PD have also been refined, and new treatment modalities and advances implemented. Reflecting these changes, this second edition features chapters devoted to genetic aspects of PD, non-motor features of the disease, and aspects of the pathophysiology, pathogenesis, and treatment of PD. Print ISBN: 978-1-4398-0714-9 eBook ISBN: 978-1-4398-0715-6 October 2012, 8-1/2 x 11, 1308 pp. Suggested Price: $250.00 / £159.00
Principles of Neural Coding Edited by
Rodrigo Quian Quiroga University of Leicester, UK
Stefano Panzeri University of Glasgow, UK and Italian Institute of Technology, Asti
Written by renowned experts in the field, this book provides a comprehensive and up-to-date overview of neural coding. It describes the basic principles, covers some of the major developments in the area, and presents a complete view of how neurons in the brain encode information. The text not only contains the most important experimental findings, but also explores the main methodological aspects for studying neural coding. In addition, the book describes alternative approaches based on simulations with neural networks and in silico modeling.
58
Print ISBN: 978-1-4398-5330-6 eBook ISBN: 978-1-4398-5331-3 May 2013, 7 x 10, 663 pp. Suggested Price: $149.95 / £95.00
Binghamton University, New York, USA
Jonathan D. Victor Weill Medical College of Cornell University, New York, USA Series: Frontiers in Neuroscience
Neuronal communication forms the basis for all behavior, from movement to thought processes. Among the many mechanisms that support these functions, spike timing is among the most powerful. This volume examines the function of spike timing in sensory, motor, and integrative processes. The first section of the book describes the foundation for quantitative analysis and theory. It examines the information contained in spike timing, how it can be quantified, and how neural systems can extract it. The second section explores how input-output relationships are reflected in spike timing across a range of sensory systems. Print ISBN: 978-1-4398-3815-0 eBook ISBN: 978-1-4398-3816-7 May 2013, 6-1/8 x 9-1/4, 442 pp. Suggested Price: $149.95 / £95.00
The Textbook of Nanoneuroscience and Nanoneurosurgery Edited by
Babak Kateb Cedars Sinai Medical Center, West Hollywood, California, USA
John D. Heiss National Institutes of Health, Bethesda, Maryland, USA
Providing a state-of-the-art review of this quickly evolving field, this groundbreaking volume presents current information about nanoplatforms and their use in neurosurgery, neurology, neuroscience, and neuroradiology. The text focuses on the educational gap across different disciplines, emphasizing the importance of integrating nanotechnology into clinical practice. The contributors review currently available nanoplatforms developed for cancer imaging, drug delivery, and therapeutics for neurological disorders. They also address regulatory guidelines and safety issues. Print ISBN: 978-1-4398-4941-5 eBook ISBN: 978-1-4398-4942-2 July 2013, 7 x 10, 602 pp. Suggested Price: $299.95 / £191.00
Rational Basis for Clinical Translation in Stroke Therapy
The Neuroscience of Handwriting
Edited by
Applications for Forensic Document Examination
Giuseppe Micieli Director of the Department of Emergency Neurology, IRCCS, Pavia, Italy
Diana Amantea Department of Pharmacobiology, University of Calabria, Rende, Italy Series: Frontiers in Neurotherapeutics Series
During the last decades, numerous promising drugs that provided neuroprotection in the laboratory setting failed to translate into the clinic because of their toxicity or lack of efficacy. However, these apparently disappointing results have provided valuable lessons to improve research strategies and enhance their clinical translation. In this scenario, by bringing together the experience developed by stroke researchers and clinicians, the book provides a precious tool for improving stroke patients’ treatment and management. Print ISBN: 978-1-4665-9497-5 May 2014, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $149.95 / £95.00
Michael P. Caligiuri University of California-San Diego, La Jolla, USA
Linton A. Mohammed Rile, Hicks, & Mohammed, San Bruno, California, USA
Bridging the gap between theory and practice, this volume examines the essential neuroscientific principles underlying normal and pathological hand motor control and handwriting. The book discusses fundamental principles in the neuroanatomy and neurochemistry of hand motor control and their application to research in handwriting. It examines the epidemiology, pathophysiology, and motor characteristics of neurogenerative diseases and their effects on handwriting and also describes the impact of psychotropic medications, substance abuse, and aging. The authors present new findings on the kinematic analyses of genuine, disguised, and forged signatures and include their laboratory research on authentic and forged signatures. Print ISBN: 978-1-4398-7140-9 eBook ISBN: 978-1-4398-7141-6 February 2012, 6-1/8 x 9-1/4, 267 pp. Suggested Price: $146.95 / £93.00
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Transcranial Brain Stimulation Edited by
Carlo Miniussi, Walter Paulus, and Paolo M. Rossini
Computational Methods for Reproductive and Developmental Toxicology Edited by
Recent years have seen the introduction and rapid development of non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES). This book reviews these recent advances made in the understanding of brain stimulation techniques. The text presents the wide range of possible brain stimulation applications in combination with neuroimaging and discusses what new information can be gained from using this technique on the dynamics of brain functions, hierarchical organization, and effective connectivity. With this timely resource, the authors aim to make a substantial impact on many areas of clinical and basic neuroscience. Print ISBN: 978-1-4398-7570-4 eBook ISBN: 978-1-4398-7571-1 December 2012, 6-1/8 x 9-1/4, 465 pp. Suggested Price: $159.95 / £99.00
Viral Hemorrhagic Fevers Edited by
Sunit K. Singh Centre for Cellular and Molecular Biology, Hyderabad, India
Daniel Ruzek Biology Centre ASCR- Institute of Parasitology, Ceske Budejovice, Czech Republic
Viral hemorrhagic fevers (VHFs) are a group of febrile illnesses caused by RNA viruses from several viral families. These infectious viruses lead to a potentially lethal disease syndrome characterized by fever, malaise, vomiting, mucosal and gastrointestinal bleeding, edema, and hypotension. The four viral families known to cause VHF disease in humans naturally reside in an animal reservoir host or arthropod vector. This volume presents the most current information on each virus. It examines the fevers caused by these viruses, their mechanisms for spreading, their molecular pathogenesis, host pathogen immune interactions, and detection, treatment, and prevention. Print ISBN: 978-1-4398-8429-4 eBook ISBN: 978-1-4398-8431-7 July 2013, 7 x 10, 596 pp. Suggested Price: $149.95 / £95.00
Donald R. Mattison National Institute of Health, Bethesda, Maryland, USA Series: QSAR in Environmental and Health Sciences
Building from the perspective of reproductive and developmental biology, this volume provides a timely, comprehensive overview of computational approaches in reproductive and developmental toxicology. The book reviews the complexity of reproductive and developmental processes and the large number of chemicals in the environment and in drug development to which adults of reproductive age are exposed or treated. It highlights the need to determine those that represent potential hazards and strategies for evaluating that information. The text includes legislative initiatives focusing on the identification of reproductive and developmental hazards while reducing use of animals. Print ISBN: 978-1-4398-6107-3 May 2013, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $159.95 / £99.00
CRC World Dictionary of Medicinal and Poisonous Plants Common Names, Scientific Names, Eponyms, Synonyms, and Etymology, Five-Volume Set Umberto Quattrocchi Universita di Palermo, Italy
Written as a reference to be used within university, departmental, public, institutional, herbaria, and arboreta libraries, this book provides the first starting point for better access to data on medicinal and poisonous plants. Following on the success of the author’s CRC World Dictionary of Plant Names and the CRC World Dictionary of Grasses, the author provides the names of thousands of genera and species of economically important plants. It serves as an indispensable time-saving guide for all those involved with plants in medicine, food, and cultural practices as it draws on a tremendous range of primary and secondary sources. This authoritative lexicon is much more than a dictionary. It includes historical and linguistic information on botany and medicine throughout each volume. Print ISBN: 978-1-4200-8044-5 May 2012, 8-1/2 x 11, 3960 pp. Suggested Price: $1295.00 / £825.00
The Chemical Components of Tobacco and Tobacco Smoke
Environmental Risk Assessment
Second Edition
A Toxicological Approach
Alan Rodgman
Ted Simon
Winston-Salem, North Carolina, USA
Ted Simon LLC, Winston, Georgia, USA
Thomas A. Perfetti
Risk assessment is of increasing importance as health and safety regulations grow and become more complicated. Focusing on environmental risk assessment, this book looks at various factors relating to exposure and toxicity, human health, and risk. The book is aimed at practitioners and students who need to know more about understanding, developing, conducting, and interpreting risk assessments. It provides sufficient background to enable readers to probe for themselves the science underlying the key issues in environmental risk.
Perfetti and Perfetti, LLC, Winston-Salem, North Carolina, USA
Adding to the progress reported in the First Edition from the early 1800s to late 2008, The Chemical Components of Tobacco and Tobacco Smoke, Second Edition provides nearly 7,000 references on almost 9,600 components. The authors discuss the controversies over the extrapolation of the biological effect of a specific component administered individually by one route versus its biological effect when the component is in a highly complex mixture and is administered by a different route. They also cite studies in which cigarette design technologies were developed to control the per-cigarette mainstream smoke yield of Federal Trade Commission–defined tar and one or more specific tobacco smoke components of concern.
Neuroscience / Toxicology
Series: Frontiers in Neuroscience
Print ISBN: 978-1-4665-9829-4 January 2014, 6 x 9, 416 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4665-1548-2 eBook ISBN: 978-1-4665-1552-9 February 2013, 8-1/2 x 11, 2332 pp. Suggested Price: $299.95 / £191.00
For more information and a complete list of titles, visit us at www.crcpress.com
59
Textbook
Forensic Toxicology
Third Edition
Mechanisms and Pathology
Edited by
Robert H. Powers
Harry Salem
Connecticut Department of Public Safety, Hartford, USA
US Army Chemical and Biological Center, Aberdeen, Maryland
Dorothy E. Dean
Sidney A. Katz
Summit County Medical Examiner’s Office, Akron, Ohio, USA
Toxicology 60
Inhalation Toxicology
This book goes beyond the simple analysis of identifying the substance to provide an understanding of the mechanisms of action of drugs and their physiologic and pathologic consequences on an affected organ system. This is the step that allows a forensic pathologist to determine cause of death. A significant section of the book is dedicated to an overview of organ system physiology and pathology, and the toxins/toxic mechanisms impacting those systems. Where appropriate, the book presents case histories, photographs of gross pathology, and photomicrographs. Print ISBN: 978-1-4665-8194-4 May 2014, 8-1/2 x 11 Suggested Price: $139.95 / £89.00
Rutgers University, Camden, New Jersey, USA
Fully updated with new research and discoveries since the last edition, this third edition emphasizes the relationship between the respiratory system and toxicology of inhaled substances. Filled with contributions from internationally recognized scientists from academic, industrial, and governmental sectors, the book presents chapters on the updated testing procedures and equipment guidelines for Europe and North America. This edition includes new material on nonoparticles, the use of microelectronics for studying inhalation toxicology, and emergency response strategies. Print ISBN: 978-1-4665-5273-9 June 2014, 7 x 10, 768 pp. Suggested Price: $179.95 / £114.00
Forensic Toxicology
Kidney
Medico-Legal Case Studies
Toxicological Assessment
Kalipatnapu N. Rao
Edited by
University of Pittsburgh Medical Center, Pennsylvania, USA
Sang Geon Kim
Modern technology using state-of-the-art equipment can now identify almost any toxin relevant to a legal issue. Tracking the progression of toxicology findings from the laboratory to the courtroom, this volume prepares practicing toxicologists to write reports and testify at depositions and in court. Topics include determining serum/blood ethanol levels, ethylene glycol poisoning, plant and animal toxins, alcohol intoxication, synergistic effects of alcohol and drugs, prescription drug overdose, toxic torts, and workers’ compensation issues. Written in an accessible style, this volume is essential for forensic toxicologists who need to understand how to best present the science of toxicology in the forensic arena.
Seoul National University, South Korea
Print ISBN: 978-1-4398-6681-8 eBook ISBN: 978-1-4398-6682-5 February 2012, 6-1/8 x 9-1/4, 289 pp. Suggested Price: $104.95 / £66.99
Print ISBN: 978-1-4665-8811-0 eBook ISBN: 978-1-4665-8812-7 September 2013, 6-1/8 x 9-1/4, 234 pp. Suggested Price: $99.95 / £63.99
Handbook of Toxicology
Nanotoxicology
Third Edition Edited by
Progress toward Nanomedicine, Second Edition
Michael J. Derelanko
Edited by
Honeywell International Inc., Morristown, New Jersey, USA
Nancy A. Monteiro-Riviere
Carol Auletta
Bridging the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments, this book describes major areas of progress in the laboratory and clinic. In the first section, aspects of cellular organelles are discussed. The second section covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. In the third section, the recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally, the book discusses clinical implications of acute and chronic renal toxicity.
Kansas State University, Manhattan, USA
Huntington Life Sciences, East Millstone, New Jersey, USA
C. Lang Tran
This third edition of a classic volume contains contributions from experts who provide both fundamental and applied information. Providing a fresh perspective on several topics, this edition contains completely rewritten chapters on immunotoxicology and endocrine, reproductive, and developmental toxicology. Chapters on neurotoxicology and inhalation and regulatory toxicology have been updated and consolidated. The format of the book is designed to allow working toxicologists to locate basic information quickly. A separate glossary is included with terms presented both alphabetically and by toxicological subspecialty.
Institute of Occupational Medicine, Edinburgh, UK
Print ISBN: 978-1-4398-9013-4 February 2014, 8-1/2 x 11, 1000 pp. Suggested Price: $169.95 / £108.00
Revised and updated, this second edition of Nanotoxicology covers the principles of nanotechnology and its potential adverse effects on human health. With a focus on different pathways of hazard exposure, the book examines the interaction of nanomaterials with biological systems, including membrane transfer, screening methods, and impact on major organs via dermal, oral, and respiratory routes. Print ISBN: 978-1-4822-0387-5 March 2014, 6-1/8 x 9-1/4, 512 pp. Suggested Price: $169.95 / £108.00
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Natural Products Interactions on Genomes
Toxicologic Pathology
Edited by
Edited by
Siva Somasundaram
Pritam S. Sahota, James A. Popp, Jerry F. Hardisty, and Chirukandath Gopinath
Written for students, researchers, and professionals in fields related to biology, biomedical science, naturopathic and herbal medicine, pharmacy, and medical chemistry, this timely reference focuses on the recent developments of the human genome interacting with various natural products. As traditional references only cover information on natural products specific to certain metabolic pathways, this book offers a collection of all genomic interactions with various natural products and discusses the product’s use in prevention and/or treatment of disease. An interactive Web tool is provided as well, that automatically updates literature of natural products and its interacting metabolic pathways. Print ISBN: 978-1-4398-7231-4 May 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $149.95 / £95.00
Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, this book presents histopathologic descriptions of lesions observed in drug development. Each section contains information related to the lesion to assist the pathologist in making a determination of its origin, and potential biological significance, as well as its relevance while assessing human risk. Organ-based chapters include a description of light microscopic and electron microscopic description of pathological lesions, differential diagnoses, and biological consequences, pathogenesis and/ or mechanism of lesion formation, and expected clinical pathology correlates. This book is also a valuable reference for toxicologists to assist in understanding compound-related pathological findings and to provide background for interaction with pathologists. Print ISBN: 978-1-4398-7210-9 eBook ISBN: 978-1-4398-7212-3 April 2013, 7 x 10, 1015 pp. Suggested Price: $259.95 / £172.00
Ovarian Toxicology Second Edition Edited by
Patricia B. Hoyer The University of Arizona, College of Medicine, Tucson, USA
Researchers have substantially contributed to our understanding of the impact of xenobiotics and environmental factors on ovarian function. This volume substantially updates newly investigated ovotoxicants as well as improved mechanistic insights that have emerged since the first edition. Topics include ovarian physiology and the metabolism of xenobiotics; the effect of pesticides, heavy metals, phthalates, BPA, and cigarette smoking on the ovaries; ovarian cancer; and epidemiology and human health risk assessment for environmental chemicals and pharmaceuticals. The book is essential for those who would benefit from a survey of the impact of xenobiotic chemicals on ovarian function. Print ISBN: 978-1-4665-0406-6 eBook ISBN: 978-1-4665-0407-3 September 2013, 6-1/8 x 9-1/4, 387 pp. Suggested Price: $159.95 / £99.00
Applying Genomic and Proteomic Microarray Technology in Drug Discovery Second Edition Robert S. Matson QuantiScientifics, LLC, Irvine, California, USA
Microarrays play an increasingly significant role in drug discovery. Updated and revised to reflect recent progress in the field, the second edition of this volume discusses omics-driven applications, the commercialization of the microarray platform, and solid-supports (substrates) and surface chemistries currently used in the creation of nucleic acid and protein microarrays. It examines different approaches to producing microarrays that achieve spot equality with the same number of molecules properly oriented. It also explores the development of the gene expression microarray and representative applications and the development of protein microarray technology. Print ISBN: 978-1-4398-5563-8 eBook ISBN: 978-1-4398-5564-5 March 2013, 6-1/8 x 9-1/4, 322 pp. Suggested Price: $149.95 / £95.00
Seafood and Freshwater Toxins Pharmacology, Physiology, and Detection, Third Edition Edited by
Jen-pei Liu, Shein-Chung Chow, and Chin-Fu Hsiao
University of Santiago, Lugo, Spain
This book provides an overview of the current state of knowledge from several perspectives. Incorporating toxicology, chemistry, ecology, and economics, the book covers the biological aspects of the bloom and the effects and actions of each toxin, with emphasis on human response. It discusses the use of animals, receptors, antibodies, and aptamers as tools for method development. It highlights the legal and economic perspectives of toxic incidence in industrial activity and international regulation and monitoring programs. Print ISBN: 978-1-4665-0514-8 March 2014, 7 x 10, 1220 pp. Suggested Price: $249.95 / £159.00
Design and Analysis of Bridging Studies Edited by
Luis M. Botana
Toxicology / Biopharmaceuticals
Series: Clinical Pharmacognosy Series
Nonclinical Safety Assessment
Series: Chapman & Hall/CRC Biostatistics Series
Taking into account the International Conference Harmonisation E5 framework for bridging studies, this book covers the regulatory requirements, scientific and practical issues, and statistical methodology for designing and evaluating bridging studies and multiregional clinical trials. For bridging studies, the authors explore ethnic sensitivity, the necessity of bridging studies, types of bridging studies, and the assessment of similarity between regions based on bridging evidence. For multiregional clinical trials, the text considers regional differences, assesses the consistency of treatment effect across regions, and discusses sample size determination for each region. Print ISBN: 978-1-4398-4634-6 eBook ISBN: 978-1-4398-4635-3 July 2012, 6-1/8 x 9-1/4, 287 pp. Suggested Price: $104.95 / £66.99
For more information and a complete list of titles, visit us at www.crcpress.com
61
Encyclopedia of Biopharmaceutical Statistics
A Practical Guide to Human Research and Clinical Trials
Third Edition
M.U.R. Naidu and P. Usha Rani
Edited by
Shein-Chung Chow Duke University, School of Medicine, Durham, North Carolina, USA
Biopharmaceuticals 62
Widely used by pharmaceutical scientists, clinical researchers, and biostatisticians, the third edition of this definitive reference includes 89 new chapters, bringing the total number of chapters to 230. It provides updated information on changes in regulatory requirements for drug review/approval processes and reflects recent developments in statistical design and methodology. This edition also covers new topics, including adaptive design in clinical research, translational medicine, statistical genetics, biomarker development, target clinical trials, follow-on biologics, and Traditional Chinese Medicine.
Nizam’s Institute of Medical Sciences, Hyderabad, India
Designed to be a teaching aid and reference guide, this book focuses on ethics, regulations, and guidelines for human research and clinical trials. Conducting a successful clinical trial requires not only a strong basic knowledge, but also hands-on practical training. The book explains the intricate details of the subject to readers by citing concrete cases, exercises, and templates along with the theoretical aspects. Prof. M.U.R Naidu and his co-authors address all aspects of clinical trials from clinical research, drug development, and quality to methodology, biostatistics, and pharmacovigilance. Print ISBN: 978-1-4665-9117-2 January 2013, 6-1/8 x 9-1/4, 350 pp. Suggested Price: $139.95 / £89.00
Print ISBN: 978-1-4398-2245-6 eBook ISBN: 978-1-4822-1866-4 May 2010, 8-1/2 x 11, 1504 pp. Suggested Price: $848.00 / £540.00
Fermentation Microbiology and Biotechnology
Probiotic Bacteria
Third Edition
Fundamentals, Therapy and Technological Aspects
Edited by
Edited by
E.M.T. El-Mansi, C.F.A. Bryce, Arnold L. Demain, and A.R. Allman
J. Paulo Sousa e Silva
Exploring the diverse array of metabolic pathways employed for the production of primary and secondary metabolites and biopharmaceuticals, this volume addresses the whole spectrum of fermentation biotechnology, from fermentation kinetics and dynamics to protein and co-factor engineering. The third edition extends the spectrum of the book to reflect the multidisciplinary and buoyant nature of this subject area. Four new chapters are included: Functional Genomics, Solid-State Fermentations, Applications of Metabolomics to Microbial Cell Factories, and Current Trends in Culturing Complex Plant Tissues for the Production of Metabolites and Elite Genotypes.
Instituto Piaget – ISEIT, Viseu, Portugal
University of Porto, Portugal
Ana Cristina Freitas Complied by an expert editorial team with noteworthy and remarkable experience, this book covers technological aspects related to probiotics, not only in terms of delivery modes but also in terms of protection technologies. It includes discussions of their therapeutic and physiologic implications and benefits, and provides a contemporary update and a holistic review of the topic. It focuses on the technological aspects of probiotic products, brings together the information needed for their successful development, and examines the international picture regarding regulatory issues.
Print ISBN: 978-1-4398-5579-9 eBook ISBN: 978-1-4398-5581-2 December 2011, 7 x 10, 555 pp. Suggested Price: $146.95 / £93.00
Print ISBN: 978-981-4411-62-2 February 2014, 6 x 9, 300 pp. Suggested Price: $149.95 / £95.00
Fungal Enzymes
Quality Operations Procedures for Pharmaceutical, API, and Biotechnology
Edited by
Maria de Lourdes T. M. Polizeli Mahendra Rai Amravati Univeristy, Maharashtra, India
This book presents a detailed account of different enzymes including pectinolytic and amylolytic systems, invertases, cellulases and hemicellulases, pectinases, proteases, laccases, phytases, alpha-glucuronidases, mannanases, and lipases produced by different fungi. It also deals with many applications, including the transesterification and production of biodiesel. The text incorporates different approaches to diverse enzyme systems—for a better understanding of the substrates involved in catalysis—as well as different processes of enzyme production, purification processes, gene and metabolic regulations, and engineering of enzymes. Print ISBN: 978-1-4665-9454-8 eBook ISBN: 978-1-4665-9455-5 July 2013, 6-1/8 x 9-1/4, 464 pp. Suggested Price: $129.95 / £82.00
Syed Imtiaz Haider Erfan Syed Asif This book classifies the various aspects of quality operations as separately designed operating procedures and provides a systematic description for each element. Addressing local and international compliance, the author presents technical solutions to fulfill the needs of quality assurance and quality control systems of all grades. The text presents standard operating procedures for documentation guidelines, validation guidelines, handling of materials in microbiological labs, process simulation testing, conducting internal audits, and chemical and biological testing. An accompanying CD-ROM offers valuable key performance indicator templates. Print ISBN: 978-1-4398-8690-8 eBook ISBN: 978-1-4398-8692-2 June 2012, 7 x 10, 584 pp. Suggested Price: $135.95 / £86.00
www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Regenerative Medicine, Stem Cells and the Liver
Bayesian Adaptive Methods for Clinical Trials
David C. Hay
Scott M. Berry, Bradley P. Carlin, J. Jack Lee, and Peter Muller
The regenerative capacity of the liver has been recognized for centuries, but when it is overwhelmed by insulting stimuli or is chronically damaged, its regenerative capability is substantially reduced or lost. Researchers have been working to find solutions to cure failing human liver function. Given the ability of stem cells to self-renew and differentiate into specialized cell liver types, they represent an attractive strategy to replace lost liver function. This book begins by outlining the complex nature of human liver disease and proceeds to examine the potential that stem cell-based approaches have to offer. Print ISBN: 978-1-57808-739-6 eBook ISBN: 978-1-4665-1385-3 April 2012, 6-1/8 x 9-1/4, 200 pp. Suggested Price: $104.95 / £66.99
Series: Chapman & Hall/CRC Biostatistics Series
Written by leading pioneers of Bayesian clinical trial designs, this book explores the growing role of Bayesian thinking in clinical trial analysis. Covering phase I, II, and III clinical trials, it establishes the basic principles before extending them to specific phases and endpoints. The authors also discuss special topics that span different phases of the process, including the use of historical data, equivalence studies, multiplicity and multiple comparisons, and subgroup analysis. They provide many detailed examples drawing on real data sets. Along with other materials, the R and WinBUGS codes used throughout are available on supporting websites. Print ISBN: 978-1-4398-2548-8 eBook ISBN: 978-1-4398-2551-8 July 2010, 6-1/8 x 9-1/4, 323 pp. Suggested Price: $104.95 / £65.99
Biosimilars
Textbook
Batch Processing Modeling and Design
Design and Analysis of Follow-on Biologics
Urmila Diwekar
Shein-Chung Chow
Vishwamitra Research Institute, Clarendon Hills, Illinois, USA
The book describes various unit operations in batch and bioprocessing and design methods for these units. Numerical methods are necessary to solve these design problems. The time-dependent nature of batch processes result in challenging scheduling and planning problems. Further, every unit encounters optimal control problems. This book provides basics to solve these problems. It is intended as a textbook for grad-level batch process courses as well as reference book for researchers and practitioners. Print ISBN: 978-1-4398-6119-6 January 2014, 6-1/8 x 9-1/4, 274 pp. Suggested Price: $149.95 / £95.00
Duke University School of Medicine, Durham, North Carolina, USA Series: Chapman & Hall/CRC Biostatistics Series
Written by a top biostatistics researcher, this is the first book entirely devoted to the statistical design and analysis of biosimilarity and interchangeability of biosimilar products. It includes comparability tests of important quality attributes at critical stages of the manufacturing processes of biologic products. The book focuses on the scientific factors and practical issues related to the design and analysis of biosimilar studies. It covers most of the statistical questions encountered in various study designs at different stages of research and development of biological products. Print ISBN: 978-1-4665-7969-9 eBook ISBN: 978-1-4665-7970-5 July 2013, 6-1/8 x 9-1/4, 444 pp. Suggested Price: $89.95 / £57.99
Process Validation in Manufacturing of Biopharmaceuticals
Causal Inference Miguel A. Hernan and James M. Robins Harvard School of Public Health, Boston, Massachusetts, USA
Third Edition Edited by
Anurag S. Rathore Indian Institute of Technology, New Delhi
Gail Sofer SofeWare Associates, Austin, Texas, USA Series: Biotechnology and Bioprocessing
Written by experienced authorities in process validation, this book explores strategies for selecting the most appropriate quality control processes. It offers practical guidelines, recommendations, and an abundance of industrial case studies that demonstrate various techniques and approaches in the validation of biopharmaceutical processes. This third edition of the text addresses the numerous changes made in the pharmaceutical industry as well as the many modifications that have been made to regulations. In addition, the authors cover advances in biotechnology.
The application of causal inference methods is growing exponentially in fields that deal with observational data. Written by pioneers in the field, this practical book presents an authoritative yet accessible overview of the methods and applications of causal inference. With a wide range of detailed, worked examples using real epidemiologic data as well as software for replicating the analyses, the text provides a thorough introduction to the basics of the theory for non-time-varying treatments and the generalization to complex longitudinal data. Print ISBN: 978-1-4200-7616-5 June 2014, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $49.95 / £31.99
Print ISBN: 978-1-4398-5093-0 eBook ISBN: 978-1-4398-5094-7 May 2012, 6-1/8 x 9-1/4, 531 pp. Suggested Price: $174.95 / £113.00 For more information and a complete list of titles, visit us at www.crcpress.com
Biopharmaceuticals / Bioprocessing / Clinical Trials
MRC Centre for Regenerative Medicine, University of Edinburgh, UK
63
Clinical and Statistical Considerations in Personalized Medicine
Handbook of Statistics in Clinical Oncology
Edited by
Edited by
Claudio Carini, Sandeep M Menon, and Mark Chang
John Crowley
Series: Chapman & Hall/CRC Biostatistics Series
Clinical Trials
Personalized medicine has the potential to change the way we think about, identify, and manage health problems. In the pharmaceutical industry, it is already having an exciting impact on both clinical research and patient care. This impact will continue to grow as our understanding and technologies improve. With contributions from well-known industry leaders in clinical development, this book covers the practical aspects of personalized medicine, focusing on issues that have direct application in the industry. Topics include designs for targeted therapy, adaptive designs, evidence-based adaptive statistical decisions, and design strategies for maximizing the efficiency of clinical oncology. Print ISBN: 978-1-4665-9386-2 April 2014, 6-1/8 x 9-1/4, 376 pp. Suggested Price: $89.95 / £57.99
Design and Analysis of Cross-Over Trials Third Edition Byron Jones Novartis Pharma AG, Basel, Switzerland
Michael G. Kenward Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability, 98
Since the publication of the second edition, there has been significant research and development in cross-over trials, which continue to be an important design technique in the pharmaceutical industry. This new edition has been updated with recent references and new material on analysis of small trials, analysis of baseline measurements, bioequivalence, cross-over trials in early phase drug development, and adaptive cross-over trials. The book includes numerous real examples, including some new data sets to illustrate the methods described, with SAS code available for their implementation.
64
Print ISBN: June 2014, 6-1/8 x 9-1/4, 480 pp. Suggested Price: $99.95 / £63.99
Design and Analysis of Non-Inferiority Trials Mark D. Rothmann, Brian L. Wiens, and Ivan S.F. Chan Series: Chapman & Hall/CRC Biostatistics Series
The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the issues involved in the design of a noninferiority trial. Using examples from real clinical trials, the book discusses general and regulatory issues and illustrates how they affect analysis. Each chapter begins with a non-technical introduction, so the subject is easily understood by those without prior knowledge of non-inferiority clinical trials. The book also provides detailed mathematical approaches along with their mathematical properties. Print ISBN: 978-1-58488-804-8 eBook ISBN: 978-1-58488-805-5 July 2011, 6-1/8 x 9-1/4, 454 pp. Suggested Price: $98.95 / £62.99
Third Edition Chief Executive Officer, Cancer Research and Biostatistics, Seattle, Washington, USA
Antje Hoering Senior Biostatistician, Cancer Research and Biostatistics, Seattle, Washington, USA Affiliate Assistant Professor, Department of Biostatistics, University of Washington, Seattle, USA Affiliate Investigator, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials. Accessible to statisticians in clinical trials as well as oncologists interested in clinical trial methodology, the book presents up-to-date statistical approaches to the design and analysis of oncology clinical trials. New topics in this edition include trial designs for targeted agents, Bayesian trial design, and the inclusion of high-dimensional data and imaging techniques. This edition also contains numerous figures and examples to better explain concepts. Print ISBN: 978-1-4398-6200-1 eBook ISBN: 978-1-4398-6201-8 March 2012, 6-1/8 x 9-1/4, 657 pp. Suggested Price: $125.95 / £81.00
Patient-Reported Outcomes Measurement, Implementation and Interpretation Joseph C. Cappelleri, Kelly H. Zou, Andrew G. Bushmakin, Jose M. Alvir, Demissie Alemayehu, and Tara Symonds Series: Chapman & Hall/CRC Biostatistics Series
Covering conceptual and statistical methods, this book discusses the issues related to measuring and interpreting patient reported outcomes (PROs). It begins with a review and background information and then covers measurement scales, validity and reliability, item response theory, and missing data. The book also describes various statistical analysis techniques, including exploratory, cross-sectional, and longitudinal data analysis, and highlights the practical interpretation and application of the techniques in clinical and pharmaceutical settings. SAS code for all methods is available in an appendix and online. Print ISBN: 978-1-4398-7367-0 December 2013, 6-1/8 x 9-1/4, 350 pp. Suggested Price: $99.95 / £63.99
Quantitative Evaluation of Safety in Drug Development Design, Analysis and Reporting Edited by
Qi Jiang and H. Amy Xia Amgen Inc, Thousand Oaks, California, USA Series: Chapman & Hall/CRC Biostatistics Series
Drug safety has always been important, but it’s taken on increasing criticality and scrutiny in recent years. This book covers the most state-of-the-art methods in drug safety assessment. In addition, statistical methods for drug safety assessment are still evolving and new methods are under development. This book is designed to bring the most-advanced knowledge and statistical methodology to the statistical/clinical/safety community, share best practices, and stimulate further research and methodology development in the drug safety area. Print ISBN: 978-1-4665-5545-7 June 2014, 6-1/8 x 9-1/4, 275 pp. Suggested Price: $99.95 / £63.99
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Randomized Phase II Cancer Clinical Trials
Dictionary of Antibiotics & Related Substances
Sin-Ho Jung
with CD-ROM, Second Edition
Series: Chapman & Hall/CRC Biostatistics Series
Suitable for cancer clinicians and biostatisticians, this book explains how to properly select and accurately use diverse statistical methods for designing and analyzing phase II trials. The author first reviews the statistical methods for single-arm phase II trials since some methodologies for randomized phase II trials stem from single-arm phase II trials and many phase II cancer clinical trials still use single-arm designs. The book then presents methods for randomized phase II trials and describes statistical methods for both single-arm and randomized phase II trials. Print ISBN: 978-1-4398-7185-0 eBook ISBN: 978-1-4398-7186-7 May 2013, 6-1/8 x 9-1/4, 244 pp. Suggested Price: $89.95 / £57.99
Edited by
Barrie W. Bycroft Nottingham University, Nottingham, UK
David J. Payne GlaxoSmithKline, Collegeville, Pennsylvania, USA
Updated and expanded since its original publication, this reference covers the different classes of antibiotics, ranging from traditional antibiotics such as penicillin, which are in the process of becoming obsolete, to the latest semisynthetic and synthetically created drugs. This second edition to a popular first offers a unique comprehensive source of data on important groups of compounds created by drug companies today. There are approximately 10,000 antibiotics known, and this revised edition of the successful compilation will cover all of the different classes. Print ISBN: 978-1-4398-3952-2 August 2013, 8-1/2 x 11, 2117 pp. Suggested Price: $795.00 / £442.00
Alzheimer’s Disease Targets for New Clinical Diagnostic and Therapeutic Strategies Edited by
Michael E. Swartz
Renee D. Wegrzyn, PhD
Cambridge, Massachusetts, USA
Adlyfe, Inc., Rockville, Maryland, USA
Ira S. Krull
Alan S. Rudolph, PhD, MBA Center for Neuroengineering, Duke University, Durham, North Carolina, USA Series: Frontiers in Neuroscience
In recent years, a tremendous amount of effort has been focused on better understanding the fundamentals of Alzheimer’s disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. This volume provides a detailed synopsis of the current state of the art of diagnostics and therapeutics and identifies emerging technologies and molecules that show promise in the management and treatment of AD. Examining current hypotheses and suggesting possible new approaches to therapeutic clinical applications, this volume paves the way for a robust pipeline of therapeutics to combat not only AD, but a whole host of other neurodegenerative diseases. Print ISBN: 978-1-4398-2708-6 eBook ISBN: 978-1-4398-2709-3 April 2012, 6-1/8 x 9-1/4, 298 pp. Suggested Price: $149.95 / £95.00
Chitin and Chitosan Derivatives Advances in Drug Discovery and Developments Edited by
Northeastern University, Boston, Massachusetts, USA
Written for practitioners in both the drug and biotechnology industries, this handbook carefully compiles the current regulatory requirements to correctly and properly validate a new or modified analytical method. The Handbook of Analytical Validation is designed to teach readers how to fully and correctly adapt new or modified analytical methods to meet regulatory requirements. The contents offer the latest regulatory requirements for submitting applications for new drugs or other applications, as regards analytical method validation. The chapters apply to both small molecules in the conventional pharmaceutical industry, as well as the biotech industry. Print ISBN: 978-0-8247-0689-0 eBook ISBN: 978-1-4200-1448-8 April 2012, 6-1/8 x 9-1/4, 220 pp. Suggested Price: $139.95 / £93.00
Handbook of Metallonutraceuticals Edited by
Yashwant Vishnupant Pathak University of South Florida, Tampa, USA
Jayant N. Lokhande
Se-Kwon Kim Pukyong National University, Busan, South Korea
This book presents current trends in chitin and chitosan derivatives, with major implications of modified chitin and chitosan derivatives for drug discovery and delivery. The current and potential applications of their derivatives in the fileds of biomedicine, nutrition, food processing, pharmacology, microbiology, agriculture, and cosmetics are vast and exciting. They are also used in various applications ranging from antibiotics and surgical sutures to dietary supplements, food and pet foods, and cloth for socks and undergarments. Applications towards drug discovery and development from preliminary research to clinical trials will be presented in this state-of-the-art publication. Print ISBN: 978-1-4665-6628-6 December 2013, 7 x 10, 527 pp. Suggested Price: $179.95 / £114.00
Handbook of Analytical Validation
Sterling Botanical, Anaheim, California, USA Series: Nutraceuticals, 3
Reviewing the health applications of selected metallic elements and the inorganic, organic, and bio-chemistry underlying the formulation of metallonutraceuticals, this comprehensive work provides a detailed description of the fundamentals and end-use applications of a series of metals vital to the metabolic and nutritional activities of human beings. Assuming a basic understanding of the role of metals in human physiology, it addresses various production issues including scaling up, processing, and automation from different scientific perspectives, as well as FDA regulations, institutional regulations, and ethics for industrial operations and corporate transactions. Print ISBN: 978-1-4398-3698-9 April 2014, 6-1/8 x 9-1/4, 336 pp. Suggested Price: $149.95 / £95.00
For more information and a complete list of titles, visit us at www.crcpress.com
Clinical Trials / Drug Discovery & Development
Duke University, Durham, North Carolina, USA
65
Making and Using Antibodies Edited by
Pharmaceutical Industry Practices on Genotoxic Impurities
Gary C. Howard
Edited by
A Practical Handbook, Second Edition The Gladstone Institutes, San Francisco, California, USA
Matthew R. Kaser Bell & Associates, San Francisco, California, USA
Drug Discovery & Development
This second edition of a popular text provides clear guidance on all aspects of how to make and use antibodies for research, and commercial and industrial applications. All chapters are revised, updated, or expanded. New material in the book includes western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present clear descriptions of basic methods for making and using antibodies and describe basic laboratory techniques in detail. Each chapter includes introductory material, allowing for a better understanding of each concept. Practical examples are also included. Print ISBN: 978-1-4398-6908-6 eBook ISBN: 978-1-4398-6910-9 July 2013, 6-1/8 x 9-1/4, 458 pp., Soft Cover Suggested Price: $149.95 / £95.00
Ocular Drug Delivery Systems Barriers and Application of Nanoparticulate Systems
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA Series: Chromatographic Science Series
This book provides readers with the current framework of genotoxicity impurity control employed in the pharmaceutical industry in response to the regulatory guidelines recently published by the FDA and EMEA. The text presents an overview of the regulatory guidelines and practical implications relevant to the pharmaceutical industry, rationales of control approaches, genotoxicity evaluation testing, and analytical methods for testing. It presents real-life case studies of genotoxic impurity control in drug substance development, drug product development, and drug degradation for clinical development and commercial manufacturing stages. Print ISBN: 978-1-4398-7420-2 May 2014, 6-1/8 x 9-1/4, 264 pp. Suggested Price: $129.95 / £82.00
Pharmacogenomics of Alcohol and Drugs of Abuse Edited by
Amitava Dasgupta
Edited by
University of Texas, Houston, USA
Deepak Thassu Actavis SSL R&D, Owings Mills, Maryland, USA
66
Heewon Lee
Loralie J. Langman
Gerald J. Chader
Mayo Clinic, Rochester, Minnesota, USA
University of Southern California Medical School, Doheny Eye Institute, Los Angeles, USA
Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in alcohol response is vital for professionals involved in alcohol rehabilitation programs. This volume focuses on how pharmacogenomic principles are applied to alcohol and drug testing and treatment and discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the text presents the genetic aspects of alcohol metabolism and drugs of abuse, including marijuana, cocaine, and amphetamine. It also covers methodologies in pharmacogenomic testing.
Written for academic and industrial researchers in the field of ophthalmology, this book presents research on the development of currently marketed devices and recent trends in the topical delivery of drugs to the posterior of the eye. Examining drug delivery barriers and the application of nano-medicines to the eye, it includes chapters on ocular physiology and the application of nanoparticles-based delivery systems to enhance drug efficacy. Contributors include leading eye researchers, surgeons, and pharmacologists from academia, the National Eye Institute, and leading ophthalmic companies such as Pfizer, Allergan, and Novartis. Print ISBN: 978-1-4398-4800-5 eBook ISBN: 978-1-4398-4801-2 October 2012, 6-1/8 x 9-1/4, 473 pp. Suggested Price: $179.95 / £113.00
Phage Display In Biotechnology and Drug Discovery Second Edition Edited by
Sachdev S. Sidhu University of Toronto, Ontario, Canada
Clarence Ronald Geyer Series: Drug Discovery Series
Until recently, the only source for information on the impact of phage display technology on drug discovery research has been laboratory manuals. A thorough reference guide and textbook, Phage Display in Biotechnology and Drug Discovery changes that scenario. It presents the theory and methods behind phage display technology, applications for peptide phage display, protein phage display, and the crucial role of phage display in the development of antibodies. Highlighting the role that phage display has and will continue to play in the discovery and development of protein therapeutics, this book provides a comprehensive overview that will excite anyone interested in recombinant antibodies.
Print ISBN: 978-1-4398-5611-6 eBook ISBN: 978-1-4398-5612-3 April 2012, 6-1/8 x 9-1/4, 252 pp. Suggested Price: $159.95 / £100.00
Theory of Drug Development Eric B. Holmgren Series: Chapman & Hall/CRC Biostatistics Series
This book focuses on the efficient development of drugs and the quantification of evidence in drug development. It presents a formal quantitative framework for understanding drug development that goes beyond simply describing the properties of the statistics in individual studies. Examining the drug development process from the perspectives of both drug companies and regulatory agencies, the author provides a rationale for underpowered phase 2 trials based on the notion of efficiency and develops a framework for evaluating the strength of evidence generated by clinical trials. Print ISBN: 978-1-4665-0746-3 eBook ISBN: 978-1-4665-0747-0 October 2013, 6-1/8 x 9-1/4, 261 pp. Suggested Price: $89.95 / £57.99
Print ISBN: 978-1-4398-3649-1 June 2014, 6-1/8 x 9-1/4, 800 pp. Suggested Price: $169.95 / £108.00 www.crcpress.com • e-mail: orders@crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524
Biopharmaceutical Supply Chains
Second Edition Daryl S. Paulson
Distribution, Regulatory, Systems and Structural Changes Ahead
BioSciences Laboratories, Inc., Bozeman, Montana, USA
Robert Handfield
Highlighting techniques for testing antibacterial compounds, this new edition of a bestselling handbook provides tips and tools for navigating the ins and outs of FDA approval procedures. It offers strategies for the servicing of expanding markets, outlines testing protocols, presents a range of testing techniques, and reviews their efficacy and appropriate uses. It also demonstrates specific methods for testing the effectiveness and safety of preinjection and preoperative washes, healthcare and food workers’ hand washes and sanitizers, and other surgical scrubs.
North Carolina State University, Raleigh, USA
Print ISBN: 978-1-4398-1322-5 June 2014, 6 x 9, 376 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4398-9970-0 eBook ISBN: 978-1-4398-9979-3 June 2012, 6-1/8 x 9-1/4, 272 pp. Suggested Price: $83.95 / £51.99
Topical Nail Products and Ungual Drug Delivery Edited by
S Narasimha Murthy The University of Mississippi, University, USA
Howard I. Maibach Department of Dermatology, University of California School of Medicine, San Francisco, USA
Presenting crucial information on the state of the science in trans-ungual drug delivery, this comprehensive overview provides a useful tool to assist in the development of products to treat and solve nail diseases. A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies. Discussing existing techniques, ongoing research, new approaches, and basic concepts in trans-ungual drug delivery, this book summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail. Print ISBN: 978-1-4398-1129-0 eBook ISBN: 978-1-4398-1131-3 September 2012, 6-1/8 x 9-1/4, 282 pp. Suggested Price: $135.95 / £86.00
Translational Medicine
Essential Management Skills for Pharmacy and Business Managers Titus De Silva This book helps pharmacists and non-pharmacist managers successfully manage the challenges of the competitive pharmacy environment, enabling them to accomplish the goals of patient-focused healthcare and improved management roles in hospital-based pharmacies and retail operations. The book presents a wealth of information and management skills for resolving issues at the workplace. Topics have been chosen to include skills in all sectors of the pharmacy environment and the author uses case studies to illustrate skills required to resolve day to day issues encountered in the pharmacy. Print ISBN: 978-1-4665-8258-3 eBook ISBN: 978-1-4665-8259-0 May 2013, 6-1/8 x 9-1/4, 464 pp. Suggested Price: $59.95 / £38.99
67 Patient-Focused Network Integration in BioPharma
The Future of Therapy?
Strategic Imperatives for the Years Ahead
Edited by
James Mittra University of Edinburgh, UK
Robert Handfield
Christopher-Paul Milne Tufts University, Boston, Massachusetts, USA
This book brings together a range of academic, industry, and practitioner perspectives on translational medicine (TM). It enhances conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure. In recognition of the various implications TM has for public health policy and commercial innovation, the book addresses the major systemic aspects of the field. The contributors explore the dynamic interactions and key challenges in translating new science into viable therapies for the clinic, which includes recognizing the importance of social, commercial, and regulatory environments in addition to good science. Print ISBN: 978-981-4316-99-6 eBook ISBN: 978-981-4364-84-3 April 2013, 6 x 9, 294 pp. Suggested Price: $149.95 / £95.00
The global pharmaceutical industry has been subjected to many challenges in the last decade, including more blockbuster drugs reaching the end of their patent life, increased regulation, pricing pressure, channel pressure, counterfeiting, and challenges in clinical trials management. This book covers the major themes and changes in the biopharmaceutical supply chain. It provides an overview of the key challenges and discusses how leading biopharma companies are dealing with these challenges. Bringing together leading researchers and industry executives, it is a must-read for those who want to learn more about achieving success in this industry.
Drug Discovery & Development / Management
Topical Antimicrobials Testing and Evaluation
North Carolina State University, Raleigh, USA
The biopharmaceutical industry as we know it today is going through a massive change that is sending shudders to the huge populations who are facing healthcare uncertainty. This book argues that patient-focused network integration is the only way for organizational evolution to occur. It discusses how to align enterprises with the patient at the center. It details the historical context of the biopharmaceutical value chain, explains the current set of challenges facing the industry, and provides a thorough presentation of the author’s unique and sustainable agenda for change. Print ISBN: 978-1-4665-5546-4 eBook ISBN: 978-1-4665-5548-8 June 2013, 6-1/8 x 9-1/4, 200 pp. Suggested Price: $69.95 / £44.99
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Pharmaceutical Accumulation in the Environment
Textbook
Prevention, Control, Health Effects, and Economic Impact
Second Edition
Edited by
Walter E. Goldstein
Pharmaceutical Science / Pharmacology 68
Goldstein Consulting Company, Las Vegas, Nevada, USA
This book describes health impact concerns, present and predicted, technologies in place and in development, and offers steps leading to proposed solutions. It suggests ways to manage risks to meet challenges that include private enterprise initiatives and public sector involvement. It proposes the type of controls needed to address pharmaceutical contamination, stressing bioreactors of particular types, augmented by process modifications needed. The book covers the impact and changes needed at sites such as hospitals, pharmaceutical factories, waste treatment plants, water purification sites, farms, and households. Print ISBN: 978-1-4665-1745-5 May 2014, 6-1/8 x 9-1/4, 224 pp. Suggested Price: $129.95 / £82.00
Scalable Green Chemistry
Basic Pharmacokinetics Mohsen A. Hedaya Associate Professor, Kuwait University, Safat Series: Pharmacy Education Series
Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. Accessible to a wide variety of readers, this volume demonstrates the quantitative pharmacokinetic relations and the interplay between pharmacokinetic parameters. Accompanying the book is a CD-ROM with self-instructional tutorials and pharmacokinetic and pharmacokineticpharmacodynamic simulations, allowing visualization of concepts for enhanced comprehension. This learning tool received an award from the American Association of Colleges of Pharmacy for innovation in teaching. Print ISBN: 978-1-4398-5073-2 eBook ISBN: 978-1-4398-9685-3 February 2012, 6-1/8 x 9-1/4, 595 pp. Suggested Price: $93.95 / £59.99
Case Studies from the Pharmaceutical Industry
Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds
Edited by
Edited by
Stefan Koenig
Goutam Brahmachari
Sepracor Inc., Marlborough, Massachusetts, USA
Packed with real-world examples, this book illustrates the 12 principles of green chemistry. These diverse case studies demonstrate to scientists and students that beyond the theory, the challenges of green chemistry in pharmaceutical discovery and development remain an ongoing endeavor. By informing and welcoming additional practitioners to this mission, the negative environmental impact of pharmaceutical products will continue to be minimized. Green chemistry is the methodology by which chemical production in this industry can become more efficient, adding environmental stewardship to the noble mission of treating human disease. Print ISBN: 978-981-4316-49-1 eBook ISBN: 978-981-4364-81-2 September 2013, 6 x 9, 350 pp. Suggested Price: $149.95 / £95.00
Visva-Bharati University, West Bengal, India
Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, this volume presents cutting-edge research in the chemistry of bioactive natural products and helps the reader understand how natural product research continues to make significant contributions in the discovery and development of new medicinal entities. The reference presents chemistry and pharmaceutical potential of natural products in modern drug discovery processes, and covers the synthesis and semi-synthesis of potentially bioactive natural products. It features chemical advances in naturally occurring organic compounds and describes their spectral properties, chemical transformations, and structure-activity relationships. Print ISBN: 978-1-4398-9167-4 eBook ISBN: 978-1-4398-9168-1 February 2013, 7 x 10, 584 pp. Suggested Price: $149.95 / £95.00
Thin Layer Chromatography in Drug Analysis
Textbook
Edited by
A Laboratory Handbook
Lukasz Komsta, Monika Waksmundzka-Hajnos, and Joseph Sherma
N R Krishnaswamy
Series: Chromatographic Science Series
It is a well-established fact that thin layer chromatography (TLC) finds broad application in drug quality control, and, despite the slight trend to replace it by other methods, many analyses are much better solved by use of TLC. This carefully structured monograph presents the most important information about pharmaceutical applications of TLC, including analysis of bulk drug material and pharmaceutical formulations, degradation studies, analysis of biological samples, optimization of the separation of drug classes, and lipophilicity estimation. Print ISBN: 978-1-4665-0715-9 December 2013, 7 x 10, 1067 pp. Suggested Price: $239.95 / £152.00
Chemistry of Natural Products Sri Sathya Sai Institute of Higher Learning, (Retired), Anantapur, Andhra Pradesh, India
This book is a companion to Chemistry of Natural Products: A Unified Approach, Second Edition. It contains a judicious mix of both spectroscopic and chemical methods of characterization of natural products. The main objective is to provide students with experimental details for the successful isolation of different types of natural products. All the experiments have been successfully class-tested. Several experimental procedures described in it are unique in the sense that they are not readily available in other books on practical organic chemistry. Additional experiments have been added to the revised edition as explained in the accompanying preface to the new edition. Print ISBN: 978-1-4665-0524-7 July 2012, 6-1/8 x 9-1/4, 216 pp. Suggested Price: $83.95 / £51.99
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Second Edition
Hormesis in Health and Disease Edited by
Suresh I. S. Rattan
Charles Dickson
Department of Molecular Biology and Genetics, Aarhus University, Denmark
Hickory, North Carolina, USA
Eric Le Bourg
Written by an author with more than 40 years of teaching experience in the field, this book responds to a critical classroom need for material on directed laboratory investigations in biological and pharmaceutical chemistry. This manual supplies 75 experiments in 22 major subject areas, including carbohydrates, lipids, and proteins in biochemistry; tannins, balsams, and alkaloids in natural products areas; and analgesics, steroids, and anesthetics in pharmaceutical chemistry. Print ISBN: 978-1-4822-2508-2 February 2014, 6-1/8 x 9-1/4, 144 pp., Soft Cover Suggested Price: $79.95 / £49.99
Université Paul-Sabatier, Centre de recherché sur la cognition animale, UMR CNRS 5169, Toulouse, France Series: Oxidative Stress and Disease
There is now a large amount of data available for human beings showing positive hormetic effects of mild stresses from physical, chemical, nutritional, and mental sources. However, these data are dispersed in the literature and not always interpreted as hormetic effects, thus restricting their full apprehension and application. A comprehensive discussion of the research, this book is composed of four sections: (1) History and terminology; (2) Evidence for hormesis in humans; (3) Molecular mechanisms of hormesis; and (4) Ethical and legal aspects, and risk assessment. Print ISBN: 978-1-4822-0545-9 May 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $129.95 / £82.00
Freshwater Phytopharmaceutical Compounds
Marine Pharmacognosy
Santhanam Ramesh, Rajabalaya Rajan, and Ramasamy Santhanam
Edited by
Producing a variety of structurally novel bioactive compounds or secondary metabolites, freshwater plants provide a diverse and unique source of bioactive lead compounds for the discovery of modern drugs. These include antibiotics, mycotoxins, alkaloids, and phenolic compounds. Bringing together biological and pharmaceutical disciplines, this reference presents key information on freshwater flora, including common names, classification, global distribution, habitats, and biology, all organized according to the activities of their bioactive compounds. These broad activities range from antimicrobial, antiviral, and anticancer to analgesic, cytotoxicity, and immunomodulatory activity.
Trends and Applications Se-Kwon Kim Pukyong National University, Busan, South Korea
Marine pharmacognosy is a dynamic field that has been systematically investigated over the last 50 years. The potential of the field is shown by the number of publications and patents that are increasing every year. This book presents the latest comprehensive studies of marine-derived medicinal substances for biological, medical, and industrial applications. Marine flora and fauna has been the source of molecules used as pharmaceuticals, cosmeceuticals, nutraceuticals, molecular probes, fine chemicals, and agrochemicals. Bringing together a global team of experts, this book provides a current snapshot of the importance of marine products in health formulation.
Print ISBN: 978-1-4665-8455-6 eBook ISBN: 978-1-4665-8456-3 August 2013, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $149.95 / £95.00
Print ISBN: 978-1-4398-9229-9 eBook ISBN: 978-1-4398-9230-5 December 2012, 7 x 10, 454 pp. Suggested Price: $159.95 / £99.00
Handbook of Aqueous Solubility Data Second Edition
Pharmaceutical Formulation Development of Peptides and Proteins
Samuel H. Yalkowsky, Yan He, and Parijat Jain
Second Edition
The second edition of this landmark volume continues the tradition of providing an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. It adds 2,000 new solubility values, bringing the total count to over 18,000 data points for more than 4,000 organic compounds. It includes data for pharmaceuticals, pollutants, nutrients, herbicides, pesticides, and agricultural, industrial, and energy-related compounds. Each compound is identified by a sequential number along with molecular formula, compound name, synonyms, molecular weight, CASR number, melting point, and boiling point if available.
Edited by
Print ISBN: 978-1-4398-0245-8 eBook ISBN: 978-1-4398-0246-5 April 2010, 7 x 10, 1620 pp. Suggested Price: $463.00 / £295.00
Pharmacology
Experiments in Pharmaceutical Chemistry
Lars Hovgaard, Sven Frokjaer, and Marco van de Weert Rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential pose a challenge for pharmaceutical scientists who have to formulate these compounds as drug products. This book focuses on general pharmaceutical developmental aspects of peptides and proteins. The general principles of production, purification, degradation mechanisms, and analysis are discussed. Several chapters address the formulation design of peptides and proteins, including protein modification and alternative administration strategies. This second edition also includes chapters on the immunogenicity of protein pharmaceuticals and the biosimulation of pharmacokinetics and pharmacodynamics. Print ISBN: 978-1-4398-5388-7 eBook ISBN: 978-1-4398-5389-4 November 2012, 6-1/8 x 9-1/4, 392 pp. Suggested Price: $169.95 / £104.00
For more information and a complete list of titles, visit us at www.crcpress.com
69
Pharmacokinetic and Pharmacodynamic Data Analysis Concepts and Applications, Fourth Edition Johan Gabrielsson Swedish University of Agricultural Sciences, Uppsala
Daniel Weiner West Virginia University, Morgantown, USA
Pharmacology / Bioinformatics
According to a review in the European Journal of Pharmaceutical Science, this book raises the stature of PK/PD modeling to its highest level. This essential professional resource is regarded as the most comprehensive and practical guide to the design, analysis, and interpretation of kinetic and dynamic experiments. It provides the expertise needed to resolve commonly appearing problems with a pedagogic yet accessible approach. For many years a staple in both undergraduate and graduate classrooms , this updated edition adds case studies to support basic concepts in PK/PD. This edition includes a CD with all exercises and WinNonlin model/command files. Print ISBN: 978-9-19-765100-4 July 2007, 1250 pp. Suggested Price: $219.95 / £141.00
Methods, Computational Algorithms, and Applications Edited by
Ming-Hui Chen, Lynn Kuo, and Paul O. Lewis Series: Chapman & Hall/CRC Mathematical & Computational Biology
Unique in its coverage of Bayesian phylogenics, this book covers advances in statistics as applied to the field of phylogenetics and coalescence-based population genetics. It is designed for statisticians who are working in phylogenetic or population genetic applications and biologists who are interested in the latest approaches to Bayesian modeling. The book includes contributions from the chief experts working in this area and provides a comprehensive overview of current research and directions for future exploration. Print ISBN: 978-1-4665-0079-2 April 2014, 6-1/8 x 9-1/4, 600 pp. Suggested Price: $99.95 / £63.99
Quantitative Pharmacology
Bioinformatics Ethics
An Introduction to Integrative Pharmacokinetic-Pharmacodynamic Analysis
Gary Skuse
Johan Gabrielsson Swedish University of Agricultural Sciences, Uppsala
Stephan Hjorth AstraZeneca R&D, Mölndal, Sweden
70
Bayesian Phylogenetics
Pharmacokinetics (PK) and pharmacodynamics (PD) comprise traditionally distinct disciplines within pharmacology, the study of the interaction of drugs with the body. This book shows that by deliberately, intimately, and systematically integrating these disciplines our understanding of drugs and the efficiency and effectiveness of drug discovery and development may be greatly enhanced. The book is therefore written with a broad audience in mind and focuses on concepts. Pharmacologists of all sorts, safety scientists, pharmacokineticists, medicinal chemists, clinicians, statisticians, veterinarians, animal science professionals, project leaders and students of medical, pharmaceutical and veterinary sciences are the primary targets.
Rochester Institute of Technology, New York, USA
Highlighting the many challenges of bioinformatics, specifically data access, security, confidentiality, and propriety, this timely book considers the changing ethical demands of those responsible for sensitive data. Practitioners increasingly engage in human healthrelated work—from clinical trials to genetic testing—all of which bring a minefield of issues. Examining a range of relevant issues, the book covers decision making in terms of access, implementation, and validation; application in the military and civilian arenas; and potential abuses and criminal uses, including sale of personal information to insurance companies. Print ISBN: 978-1-4398-1565-6 May 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $59.95 / £38.99
Print ISBN: 978-1-4665-6031-4 May 2012, 6-1/2 x 9-1/2, 264 pp. Suggested Price: $139.95 / £89.00
Safety Pharmacology in Pharmaceutical Development Approval and Post Marketing Surveillance, Second Edition Shayne C. Gad Gad Consulting Services, Cary, North Carolina, USA
Safety pharmacology is the evaluation and study of the pharmacological effects of a potential drug that are unrelated to the desired therapeutic effect. These effects often present a hazard— particularly in individuals with compromised or limited organ system functions. This volume covers safety pharmacology from the regulatory requirements down to the studies that must be done to justify them. Using the author’s more than 30 years of direct experience, the book incorporates tricks and practical insights for making studies work and understanding why they fail.
Data Mining for Bioinformatics Sumeet Dua and Pradeep Chowriappa Louisiana Tech University, Ruston, USA
Data Mining for Bioinformatics enables researchers to meet the challenge of mining vast amounts of biomolecular data to discover real knowledge. Covering theory, algorithms, and methodologies, as well as data mining technologies, it presents a thorough discussion of data-intensive computations used in data mining applied to bioinformatics. The book explains data mining design concepts to build applications and systems. Showing how to prepare raw data for the mining process, the text is filled with heuristics that speed the data mining process. Print ISBN: 978-0-8493-2801-5 eBook ISBN: 978-1-4200-0430-4 November 2012, 6-1/8 x 9-1/4, 348 pp. Suggested Price: $93.95 / £59.99
Print ISBN: 978-1-4398-4567-7 eBook ISBN: 978-1-4398-4568-4 April 2012, 6-1/8 x 9-1/4, 213 pp. Suggested Price: $159.95 / £100.00
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Polytope Projects
Edited by
Octavian Iordache
James Devillers
Polystochastic, Montreal, Canada
CTIS, Rillieux La Pape, France
How do you know what works and what doesn’t? This book contains case studies highlighting the power of polytope projects for complex problem solving. Any sort of combinational problem characterized by a large variety of possibly complex constructions and deconstructions based on simple building blocks can be studied in a similar way. Although the majority of case studies are related to chemistry, the method is general and equally applicable to other fields for engineering or science.
The honey bee is critically important for ecosystem function and biodiversity maintenance through its pollinating activity. This book provides a collection of computational methods to those primarily interested in the study of the ecology, ethology, and ecotoxicology of bees. Avoiding mathematical jargon, it presents numerous case studies to enable readers to understand the appropriateness but also the limitations of models in theoretical and applied bee research. Written by an international team of experts, this book covers the main types of modeling approaches that can be used in terrestrial ecology and applied ecotoxicology. Print ISBN: 978-1-4665-1787-5 January 2014, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $119.95 / £76.99
Print ISBN: 978-1-4822-0464-3 eBook ISBN: 978-1-4822-0465-0 October 2013, 6-1/8 x 9-1/4, 236 pp. Suggested Price: $129.95 / £82.00
Managing Your Biological Data with Python
RNA-seq Data Analysis
Allegra Via Kristian Rother
Eija Korpelainen
A Practical Approach CSC - IT Center for Science, Espoo, Finland
Adam Mickiewicz University, Poznan, Poland
Jarno Tuimala, Garry Wong, and Panu Somervuo
Anna Tramontano
Series: Chapman & Hall/CRC Mathematical & Computational Biology
University of Rome La Sapienza, Italy Series: Chapman & Hall/CRC Mathematical & Computational Biology, 52
For end-users of bioinformatics databases and tools, this book explains how to independently manage large biological data sets with Python. It covers basic aspects of computer usage as well as the simple programming of Python, showing how to use Python for biological data analysis, web interfacing of databases and scripts, and much more. The text includes many exercises and coding examples, making it ideal for self-study and classroom use. Code is also available on the authors’ website. Print ISBN: 978-1-4398-8093-7 January 2014, 6-1/8 x 9-1/4, 560 pp., Soft Cover Suggested Price: $59.95 / £38.99
RNA-seq offers unprecedented information about transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. This self-contained guide enables researchers to examine differential expression at gene, exon, and transcript level and to discover novel genes, transcripts, and whole transcriptomes. Each chapter starts with theoretical background, followed by descriptions of relevant analysis tools. The book also provides examples using both command line tools and open source graphical software, such as R, for non-computer-savvy wet lab biologists. Print ISBN: 978-1-4665-9500-2 June 2014, 7 x 10, 300 pp. Suggested Price: $69.95 / £44.99
71
Multiobjective Optimization Methodology
Applied Medical Statistics Using SAS
A Jumping Gene Approach
Geoff Der
K.S. Tang, T.M. Chan, R.J. Yin, and K.F. Man Series: Industrial Electronics
Deriving engineering designs from multiobjective optimization techniques is a challenging task, particularly when design criteria conflict performance requirements. The first book to focus on jumping genes outside bioscience and medicine, Multiobjective Optimization Methodology: A Jumping Gene Approach introduces jumping gene algorithms designed to supply viable, adequate solutions to multiobjective problems quickly and with low computational cost. Reviewing state-of-the-art multiobjective optimization techniques, it covers the fundamental concept, theoretical justification, simulation verifications, and applications of the jumping gene in evolutionary computation. The book provides the technical know-how to obtain crucial trade-off solutions between convergence and diversity. Print ISBN: 978-1-4398-9919-9 eBook ISBN: 978-1-4398-9921-2 May 2012, 6-1/8 x 9-1/4, 279 pp. Suggested Price: $146.95 / £93.00
Bioinformatics / Biostatistics & Epidemiology
In Silico Bees
University of Glasgow, Scotland
Brian S. Everitt Professor Emeritus, Institute of Psychiatry, King’s College, London (Retired), UK
Designed for medical statisticians, this intermediate-level reference explores the use of SAS for analyzing medical data. A chapter on visualizing data includes a detailed account of graphics for investigating data and smoothing techniques. The book also includes chapters on measurement in medicine, epidemiology/observational studies, metaanalysis, Bayesian methods, and handling missing data. The book maintains an example-based approach, with SAS code and output included throughout and available online. Print ISBN: 978-1-4398-6797-6 eBook ISBN: 978-1-4398-6798-3 October 2012, 6-1/8 x 9-1/4, 559 pp. Suggested Price: $93.95 / £59.99
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Applied Meta-Analysis with R Ding-Geng (Din) Chen University of Rochester, New York, USA
Karl E. Peace Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, USA Series: Chapman & Hall/CRC Biostatistics Series
Biostatistics & Epidemiology
This book provides detailed, step-by-step explanations of the implementation of meta-analysis methods using R. Each chapter gives examples of real studies compiled from the literature. After presenting the data and necessary background for understanding the applications, various methods for analyzing meta-data are introduced. The authors then develop analysis code using the appropriate R packages and functions. This systematic approach helps readers thoroughly understand the analysis methods and R implementation, enabling them to use R and the methods to analyze their own meta-data. Print ISBN: 978-1-4665-0599-5 eBook ISBN: 978-1-4665-0600-8 May 2013, 6-1/8 x 9-1/4, 342 pp. Suggested Price: $89.95 / £57.99
Bayesian Disease Mapping
Gianluca Baio Department of Statistical Science, University College London, UK Series: Chapman & Hall/CRC Biostatistics Series
Health economics is concerned with the study of the cost-effectiveness of health care interventions. This book provides an overview of Bayesian methods for the analysis of health economic data. After an introduction to the basic economic concepts and methods of evaluation, it presents Bayesian statistics using accessible mathematics. The next chapters describe the theory and practice of costeffectiveness analysis from a statistical viewpoint, and Bayesian computation, notably MCMC. The final chapter presents three detailed case studies covering cost-effectiveness analyses using individual data from clinical trials, evidence synthesis and hierarchical models and Markov models. The text uses WinBUGS and JAGS with datasets and code available online. Print ISBN: 978-1-4398-9555-9 eBook ISBN: 978-1-4398-9556-6 November 2012, 6-1/8 x 9-1/4, 243 pp. Suggested Price: $93.95 / £59.99
Hierarchical Modeling in Spatial Epidemiology, Second Edition
Benefit-Risk Assessment in Pharmaceutical Research and Development
Andrew B. Lawson
Edited by
Medical University of South Carolina, Charleston, USA Series: Chapman & Hall/CRC Interdisciplinary Statistics
This second edition provides an up-to-date, cohesive account of the full range of Bayesian disease mapping methods and applications. A biostatistics professor and WHO advisor, the author illustrates the use of Bayesian hierarchical modeling in the geographical analysis of disease through a range of real-world datasets. This edition includes new chapters on regression and ecological analysis, putative hazard modeling, and disease map surveillance as well as new appendices featuring examples of INLA and CAR models. It also presents expanded material on case event modeling and spatiotemporal analysis.
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Bayesian Methods in Health Economics
Print ISBN: 978-1-4665-0481-3 eBook ISBN: 978-1-4665-0482-0 March 2013, 6-1/8 x 9-1/4, 396 pp. Suggested Price: $89.95 / £57.99
Andreas Sashegyi, James Felli, and Rebecca Noel Series: Chapman & Hall/CRC Biostatistics Series
Bringing together the expertise of 15 contributors from academia and the industry, this book offers an easyto-read guide to the various facets of benefit-risk assessment in the major stages of pharmaceutical R&D, from early clinical development to late-stage development to regulatory review to post-launch assessment. Suitable for those in both technical and managerial roles, it enables readers to communicate more effectively across their development chain as well as rationally and thoughtfully embed benefit-risk assessment into their R&D processes. Print ISBN: 978-1-4398-6794-5 November 2013, 6-1/8 x 9-1/4, 220 pp. Suggested Price: $89.95 / £57.99
Bayesian Methods in Epidemiology
Textbook
Lyle D. Broemeling
Basic and Advanced Statistical Modeling Using SPSS
Broemeling and Associates, Medical Lake, Washington, USA Series: Chapman & Hall/CRC Biostatistics Series
Written by a biostatistics expert with over 20 years of experience in the field, this book is the first to introduce epidemiology from a Bayesian perspective. It shows epidemiologists how Bayesian models and techniques are useful in studying the association between disease and exposure to risk factors. With many examples and end-of-chapter exercises, the book employs the software package WinBUGS to carry out the analyses and offers the code in the text and for download online. Print ISBN: 978-1-4665-6497-8 eBook ISBN: 978-1-4665-6498-5 August 2013, 6-1/8 x 9-1/4, 464 pp. Suggested Price: $89.95 / £57.99
Biostatistics in Action Florin Vaida and Anya Umlauf University of California, San Diego, USA
Designed for medical researchers without a background in statistics, this text takes readers easily from basic boxplots and t-tests to linear and logistic regression and survival analysis to more complex generalized linear and nonlinear models and longitudinal data analysis. With many examples and data drawn from real biomedical research, the book focuses on practical statistical analyses using SPSS. It requires no prior statistical background and only assumes familiarity with elementary mathematics. A solutions manual and figures slides are available with qualifying course adoption. Print ISBN: 978-1-4398-7984-9 May 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $89.95 / £57.99
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Joint Models for Longitudinal and Time-to-Event Data
Epidemiology Study Design and Data Analysis, Third Edition
With Applications in R
Mark Woodward
Erasmus University Medical Center, Rotterdam, Netherlands
University of Oxford, UK; University of Sydney, Australia; and Johns Hopkins University, Baltimore, Maryland, USA Series: Chapman & Hall/CRC Texts in Statistical Science
Updated and expanded, this popular text focuses on the quantitative aspects of epidemiological research. It shows students how statistical principles and techniques can help solve epidemiological problems. Along with more exercises and examples using both Stata and SAS, this third edition includes a new chapter on risk scores and clinical decision rules, a new chapter on computer-intensive methods, and new sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines. Supporting materials are available on the book’s CRC Press web page. Print ISBN: 978-1-4398-3970-6 December 2013, 7 x 10, 816 pp. Suggested Price: $99.95 / £49.99
Handbook of Survival Analysis
Dimitris Rizopoulos Series: Chapman & Hall/CRC Biostatistics Series
Longitudinal studies often investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest. An example is prostate cancer studies where longitudinal PSA level measurements are collected in conjunction with the time-to-recurrence. This book provides a full treatment of joint models for longitudinal and timeto-event data. The content is explanatory rather than mathematically rigorous and emphasizes applications. All illustrations put forward are available in the R programming language via the freely available package JM written by the author. Print ISBN: 978-1-4398-7286-4 eBook ISBN: 978-1-4398-7287-1 June 2012, 6-1/8 x 9-1/4, 275 pp. Suggested Price: $83.95 / £51.99
Textbook
Edited by
Medical Biostatistics
John P. Klein, Hans C. van Houwelingen, Joseph G. Ibrahim, and Thomas H. Scheike
Third Edition
Series: Chapman & Hall/CRC Handbooks of Modern Statistical Methods
Series: Chapman & Hall/CRC Biostatistics Series
Survival analysis is an area of statistics that deals with timeto-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, this handbook presents modern techniques and research problems in lifetime data analysis. The book focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Print ISBN: 978-1-4665-5566-2 July 2013, 7 x 10, 656 pp. Suggested Price: $99.95 / £63.99
Abhaya Indrayan The third edition of this acclaimed reference focuses on the statistical aspects of medicine with a medical perspective, showing how biostatistics is a useful tool to manage some medical uncertainties. This edition includes several new topics, provides expanded coverage of many other topics and includes software illustrations. The author presents step-by-step explanations of statistical methods with the help of numerous real-world examples. Guide charts at the beginning of the book enable quick access to the relevant statistical procedure, and the comprehensive index at the end makes it easier to locate terms of interest. Print ISBN: 978-1-4398-8414-0 eBook ISBN: 978-1-4665-1391-4 August 2012, 6-1/8 x 9-1/4, 1024 pp. Suggested Price: $135.95 / £86.00
Interval-Censored Time-to-Event Data
Textbook
Methods and Applications
Modelling Survival Data in Medical Research
Edited by
Second Edition
Ding-Geng (Din) Chen, Jianguo Sun, and Karl E. Peace
David Collett
Series: Chapman & Hall/CRC Biostatistics Series
Series: Chapman & Hall/CRC Texts in Statistical Science
A practical guide for biomedical researchers, clinicians, biostatisticians, and graduate students in biostatistics, this volume covers the latest developments in the analysis and modeling of interval-censored time-toevent data. Top researchers from academia, biopharmaceutical industries, and government agencies show how up-to-date statistical methods are used in biopharmaceutical and public health applications. The book presents data from actual clinical trials and biomedical research, including breast cancer and HIV data sets. It also offers easy access to computational methods and R software packages.
Profusely illustrated with examples and written in an easyto-follow style, this practical guide begins with an introduction to survival analysis and a description of four studies that lead to survival data. Subsequent chapters then use those data sets and others to illustrate various analytical techniques applicable to such data. This second edition features a more detailed treatment of parametric models, accelerated failure time models, and analysis of intervalcensored data. It also illustrates methods using SAS to generate and examine output in detail.
Print ISBN: 978-1-4665-0425-7 eBook ISBN: 978-1-4665-0428-8 July 2012, 6-1/8 x 9-1/4, 433 pp. Suggested Price: $104.95 / £66.99
Biostatistics & Epidemiology
Textbook
UK Transplant, Bristol
Print ISBN: 978-1-58488-325-8 March 2003, 6-1/8 x 9-1/4, 408 pp., Soft Cover Suggested Price: $87.95 / £55.99
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Multivariate Survival Analysis and Competing Risks Martin J. Crowder Imperial College, University of London, UK Series: Chapman & Hall/CRC Texts in Statistical Science
Biostatistics & Epidemiology
Suitable for graduate students and researchers in statistics and biostatistics as well as those in the medical field, epidemiology, and social sciences, this book introduces univariate survival analysis and extends it to the multivariate case. It also covers competing risks and counting processes and provides many real-world examples, exercises, and R code. The text discusses survival data, survival distributions, frailty models, parametric methods, multivariate data and distributions, copulas, continuous failure, parametric likelihood inference, and non- and semi-parametric methods. Print ISBN: 978-1-4398-7521-6 eBook ISBN: 978-1-4398-7522-3 April 2012, 6-1/8 x 9-1/4, 417 pp. Suggested Price: $104.95 / £66.99
Regression Models as a Tool in Medical Research Werner Vach Institute of Medical Biometry and Medical Informatics, Freiburg, Germany
While regression models have become standard tools in medical research, understanding how to properly apply the models and interpret the results is often challenging for beginners. This text presents the fundamental concepts and important aspects of regression models most commonly used in medical research, including the classical regression model for continuous outcomes, the logistic regression model for binary outcomes, and the Cox proportional hazards model for survival data. The author emphasizes adequate use, correct interpretation of results, appropriate presentation of results, and avoidance of potential pitfalls. Print ISBN: 978-1-4665-1748-6 eBook ISBN: 978-1-4665-1750-9 November 2012, 6-1/8 x 9-1/4, 495 pp. Suggested Price: $93.95 / £59.99
Optimal Design for Nonlinear Response Models
Statistical Analysis of Human Growth and Development
Valerii V. Fedorov
Yin Bun Cheung
Quintiles, Durham, North Carolina, USA
Series: Chapman & Hall/CRC Biostatistics Series
Sergei L. Leonov AstraZeneca, Wilmington, Delaware, USA Series: Chapman & Hall/CRC Biostatistics Series
Drawing on the authors’ many years of experience in academia and the pharmaceutical industry, this book discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. While the focus is on nonlinear models, the book begins with an explanation of the key ideas, using linear models as examples. Applying the linearization in the parameter space, it then covers nonlinear models and locally optimal designs as well as minimax, optimal on average, and Bayesian designs. The authors also discuss adaptive designs, focusing on procedures with non-informative stopping.
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Textbook
Print ISBN: 978-1-4398-2151-0 eBook ISBN: 978-1-4398-2152-7 July 2013, 6-1/8 x 9-1/4, 402 pp. Suggested Price: $89.95 / £57.99
Designed for nonstatisticians and statisticians new to the analysis of growth and development data, this book is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. It collects methods scattered throughout the literature and explains how to use them to solve common research problems. It also discusses how well a method addresses a specific scientific question and how to interpret and present the analytic results. Stata codes are available on the book’s CRC Press web page. Print ISBN: 978-1-4398-7154-6 eBook ISBN: 978-1-4398-7156-0 November 2013, 6-1/8 x 9-1/4, 378 pp. Suggested Price: $99.95 / £63.99
Practical Statistics for Medical Research
Statistical and Computational Methods in Brain Image Analysis
Douglas G. Altman
Moo K. Chung
Textbook
University of Oxford, UK Series: Chapman & Hall/CRC Texts in Statistical Science
Practical Statistics for Medical Research is a problembased text for medical researchers, medical students, and others in the medical arena who need to use statistics but have no specialized mathematics background. The author draws on twenty years of experience as a consulting medical statistician to provide clear explanations to key statistical concepts, with a firm emphasis on practical aspects of designing and analyzing medical research. Using real data and including dozens of interesting data sets, this bestselling text gives special attention to the presentation and interpretation of results and the many real problems that arise in medical research. Print ISBN: 978-0-412-27630-9 November 1990, 6-1/8 x 9-1/4, 624 pp. Suggested Price: $115.95 / £72.99
University of Wisconsin-Madison, USA Series: Chapman & Hall/CRC Mathematical and Computational Imaging Sciences Series
The massive amount of nonstandard high-dimensional brain imaging data being generated is often difficult to analyze using current techniques. This challenge in brain image analysis requires new computational approaches and solutions. Unfortunately, few research papers or books in the field describe the quantitative techniques with detailed illustrations of actual imaging data and computer codes. Using MATLAB® and case study data sets, this is the first book to explicitly explain how to perform statistical analysis on brain imaging data. Print ISBN: 978-1-4398-3635-4 eBook ISBN: 978-1-4398-3636-1 July 2013, 6-1/8 x 9-1/4, 400 pp. Suggested Price: $99.95 / £63.99
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Textbook
Textbook
Statistics for Epidemiology
Algorithms for NextGeneration Sequencing
University of California, Berkeley, USA Series: Chapman & Hall/CRC Texts in Statistical Science
Written by one of the top biostatisticians in the field, this volume fills a substantial niche by explaining the ideas behind the analysis of epidemiological data. Requiring only knowledge of fundamental mathematics, it covers the basic material for analyzing data that arise from simple epidemiological studies, including case-control and matched studies. Methodologically, it describes stratification techniques for handling confounding and interaction and the logistic regression model. The author uses a case-study approach, following a few simple examples through several method chapters rather than introducing a different example at each stage. Print ISBN: 978-1-58488-433-0 August 2003, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $104.95 / £65.99
Textbook
Survival Analysis in Medicine and Genetics
Wing-Kin Sung National University of Singapore Series: Chapman & Hall/CRC Mathematical & Computational Biology
Due to advances in sequencing technology, we can view hundreds of millions of short reads in a few days. Sequencing technology enables us to study our genome on a large scale, but it also introduces new challenges, such as how to process vast amounts of data efficiently and how to summarize so much data. This text describes the algorithms for processing next-generation sequencing data. It also presents case studies that illustrate applications of next-generation sequencing. Print ISBN: 978-1-4665-6550-0 May 2014, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $79.95 / £49.99
Analysis of Complex Diseases A Mathematical Perspective Guanyu Wang
Jialiang Li
Fairfax, Virginia, USA
National University of Singapore
Since the clarification of the human genome, the massive accumulation of data makes it necessary to design computer models to evaluate genetic and epigenetic characteristics in terms of healthy and pathologic reactions. These models will play essential roles in future diagnostics and therapy planning of diseases. This book demonstrates the importance of physical thinking and mathematical analysis in understanding such complex systems. Taking an interdisciplinary look at this translational subject, the book explains how mathematical modeling and analysis are critical to the future of diagnostics and therapeutics in medicine.
Shuangge Ma Yale University, New Haven, Connecticut, USA Series: Chapman & Hall/CRC Biostatistics Series
Using real data sets throughout, this text introduces the latest methods for analyzing high-dimensional survival data. With an emphasis on the applications of survival analysis techniques in genetics, it presents a statistical framework for burgeoning research in this area and offers a set of established approaches for statistical analysis. The book reveals a new way of looking at how predictors are associated with censored survival time and extracts novel statistical genetic methods for censored survival time outcome from the vast amount of research results in genomics. Print ISBN: 978-1-4398-9311-1 eBook ISBN: 978-1-4665-9572-9 June 2013, 6-1/8 x 9-1/4, 381 pp. Suggested Price: $99.95 / £63.99
Biostatistics & Epidemiology / Computational Biology
Nicholas P. Jewell
Print ISBN: 978-1-4665-7221-8 December 2013, 6-1/8 x 9-1/4 Suggested Price: $129.95 / £82.00
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Writing Dissertation and Grant Proposals
Bioinformatics Database Systems
Epidemiology, Preventive Medicine and Biostatistics
Jason T.L. Wang
Lisa Chasan-Taber
New Jersey Institute of Technology, Newark, USA
Katherine G. Herbert University of Montclair, New Jersey, USA
University of Massachusetts, Amherst, USA
The scientific proposal-writing process can be a daunting experience for graduate students and young researchers. This book covers all aspects of the process, from structure and style to obtaining research grant funding. Organized much like a research proposal, the book covers identifying a research topic, drafting a hypothesis, conducting a literature review, describing methods for data collection and analysis, and presenting the proposal. The final section describes strategies for putting together a winning NIH proposal and responding to reviewer comments. Concepts are illustrated with examples, applications, exercises, and checklists of guidelines. Print ISBN: 978-1-4665-1206-1 April 2014, 6-1/8 x 9-1/4, 464 pp., Soft Cover Suggested Price: $59.95 / £38.99
This book explains the world of database systems to bioinformatics and cheminformatics database users. It begins with a survey of popular databases, including primary genetic and protein sequence, phylogenetic, structure and pathway, and microarray databases. The text discusses information management and modeling issues in these databases, addressing data quality issues as well as efforts in the data cleaning field to combat such problems. From drug discovery to the structure of various molecular components of the cell, the authors present new applications and case studies illustrating concepts in database systems. Print ISBN: 978-1-4398-1247-1 May 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $79.95 / £49.99
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Computational and Visualization Techniques for Structural Bioinformatics using Chimera
Textbook
Forbes J. Burkowski
Scottsdale Community College, Arizona, USA
University of Waterloo, Ontario, Canada Series: Chapman & Hall/CRC Mathematical & Computational Biology
Computational Biology
This book emphasizes computer programs that analyze protein structural data with program output generating data files and visual feedback in the form of a molecular display. The theoretical part of the text considers both the mathematical models related to molecular structure and the computational strategies that work with these models to derive results. The practical part of the text presents UCSF Chimera as a “workbench” that provides a Python programming environment and the ability to see program output in the molecular display. The accompanying CD-ROM includes Python code, color figures, and session files for Chimera. Print ISBN: 978-1-4398-3661-3 April 2014, 6-1/8 x 9-1/4, 256 pp. Suggested Price: $79.95 / £49.99
A Computational Model of Immune Response Filippo Castiglione IAC “M Picone”, Rome, Italy
Franco Celada Hospital for Joint Diseases, New York, USA
This book describes a computational model of the immune system reaction, C-ImmSim. The book presents the basic model as well as the various customizations to implement the description of different diseases and the way they have been used to produce new knowledge either from hypothesis or from experimental data. The book can be used as a practical guide to implement a computational model with which to study a specific disease and to try to address realistic clinical questions.
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Print ISBN: 978-1-4665-9748-8 June 2014, 6-1/8 x 9-1/4, 152 pp. Suggested Price: $99.95 / £63.99
Dynamical Models in Medicine Yang Kuang Arizona State University, Tempe, USA
John Nagy Series: Chapman & Hall/CRC Mathematical & Computational Biology
This book presents the medical and biological background of several diseases, explores specific issues for modeling, and discusses existing modeling methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of models. The book provides end-of-chapter exercises and projects, and problems with answers to test reader assimilations. The book is divided into three main sections that address mathematical oncology, mathematical immunology and virology, and dynamic diseases. Print ISBN: 978-1-58488-990-8 June 2014, 6-1/8 x 9-1/4, 500 pp. Suggested Price: $79.95 / £49.99
Genome Annotation Jung Soh, Paul M.K. Gordon, and Christoph W. Sensen Series: Chapman & Hall/CRC Mathematical & Computational Biology
This thorough overview explores automated genome analysis and annotation from its origins to the challenges of next-generation sequencing data analysis. It explains how current analysis strategies were developed, including sequencing strategies, statistical models, and early annotation systems. The authors then present visualization techniques for displaying integrated results as well as state-of-the-art annotation tools, including MAGPIE, Ensembl, Bluejay, and Galaxy. They also discuss the pipelines for the analysis and annotation of complex, next-generation DNA sequencing data. MAGPIE and Bluejay are available on a CD-ROM. Print ISBN: 978-1-4398-4117-4 eBook ISBN: 978-1-4398-4118-1 August 2012, 6-1/8 x 9-1/4, 270 pp. Suggested Price: $93.95 / £59.99
Computational Systems Biology of Cancer
Handbook of SAS® DATA Step Programming
Emmanuel Barillot, Laurence Calzone, Philippe Hupe, Jean-Philippe Vert, and Andrei Zinovyev
Arthur Li
Series: Chapman & Hall/CRC Mathematical & Computational Biology
This handbook shows readers how best to manage and manipulate data by using the DATA step in SAS, helping them avoid common problems when creating SAS data sets. The author explains that learning syntax does not solve all problems; rather, a thorough comprehension of SAS processing is needed for successful programming. He also guides readers through a programming task. In most of the examples, the author first presents strategies and steps for solving the problem, then offers a solution, and finally gives a more detailed explanation of the solution.
Drawn from the authors’ decade-long work in the cancer computational systems biology laboratory at Institut Curie, this self-contained guide explains how to apply computational systems biology approaches to cancer research. Suitable for readers in both computational and life sciences, the book provides proven techniques and tools for cancer bioinformatics and systems biology research. It explores how computational systems biology can help fight cancer in three essential aspects: categorizing tumors, finding new targets, and designing improved and tailored therapeutic strategies. Print ISBN: 978-1-4398-3144-1 eBook ISBN: 978-1-4398-3145-8 August 2012, 6-1/8 x 9-1/4, 461 pp. Suggested Price: $83.95 / £51.99
City of Hope National Medical Center, Los Angeles County, California, USA
Print ISBN: 978-1-4665-5238-8 eBook ISBN: 978-1-4665-5239-5 April 2013, 6-1/8 x 9-1/4, 275 pp. Suggested Price: $59.95 / £38.99
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Statistical Methods for QTL Mapping
Alpan Raval
Zehua Chen
Institute of Mathematical Sciences, Claremont Graduate University, California, USA
National University of Singapore
Animesh Ray School of Applied Life Sciences, Keck Graduate Institute, Claremont, California, USA Series: Chapman & Hall/CRC Mathematical & Computational Biology
With many examples throughout and clear explanations of key concepts, this book focuses on the concept of molecular and genetic interaction networks as a paradigm for interpreting the complexity of molecular biology at a genomic scale. The authors describe the experimental methods used to discover and test networks of interaction among biological molecules. They also present computational methods for predicting the interaction networks, discuss general mechanisms of network formation and evolution, and explore the application of network approaches to important problems in biology and medicine. Print ISBN: 978-1-58488-463-7 eBook ISBN: 978-1-4200-1036-7 April 2013, 6-1/8 x 9-1/4, 335 pp. Suggested Price: $79.95 / £49.99
Series: Chapman & Hall/CRC Mathematical & Computational Biology
While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. This book brings together many recent statistical techniques that address the data complexity of QTL mapping. It emphasizes the modern statistical methodology for QTL mapping as well as the statistical issues that arise during this process. The book gives the necessary biological background for statisticians without training in genetics and, likewise, covers statistical thinking and principles for geneticists. Print ISBN: 978-1-4398-6830-0 November 2013, 6-1/8 x 9-1/4, 308 pp. Suggested Price: $89.95 / £57.99
Textbook
Next Generation Sequencing Platforms, Resources and Data Analysis Edited by
Statistics and Data Analysis for Microarrays Using R and Bioconductor Second Edition Sorin Drăghici
Jennifer S. McDowall
Wayne State University, Detroit, Michigan, USA
European Bioinformatics Institute, Hinxton, UK
Elizabeth Campbell Series: Chapman & Hall/CRC Mathematical & Computational Biology
This volume presents both technical details and biologically based case studies that help put the technology of next generation sequencing (NGS) into perspective. It guides readers through the many different platforms of NGS technology, explaining the potential benefits and problems. The book also covers the data resources available and data analysis, including current resequencing protocols. The remainder of the book presents case studies from leading experts who provide a pragmatic problem solving focus for a variety of biological and medical research subjects. Print ISBN: 978-1-4398-7545-2 June 2014, 6-1/8 x 9-1/4, 306 pp. Suggested Price: $69.95 / £44.99
Quantitative Graph Theory Mathematical Foundations and Applications
Series: Chapman & Hall/CRC Mathematical & Computational Biology
Richly illustrated in color, this bestselling text provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that explains the basics of R and microarray technology as well as how to choose and apply the proper data analysis tool to specific problems. Now using R and Bioconductor, this edition has been expanded with fourteen new chapters and 600 more pages. R code is available on a CD-ROM. Print ISBN: 978-1-4398-0975-4 eBook ISBN: 978-1-4398-9677-8 December 2011, 6-1/8 x 9-1/4, 1036 pp. Suggested Price: $93.95 / £59.99
Cellular Potts Models Multiscale Extensions and Biological Applications Marco Scianna and Luigi Preziosi
Edited by
Politecnico di Torino, Italy
Matthias Dehmer Frank Emmert-Streib
Series: Chapman & Hall/CRC Mathematical & Computational Biology
Series: Discrete Mathematics and Its Applications
This work shows how the cellular Potts model can be used as a framework for model building and how extended models can achieve even better biological practicality, accuracy, and predictive power. It focuses on ways to integrate and interface the basic cellular Potts model at the mesoscopic scale with approaches that accurately model microscopic dynamics. These extensions are designed to create a nested and hybrid environment, where the evolution of a biological system is realistically driven by the constant interplay and flux of information between the different levels of description.
This book presents methods for analyzing graphs and networks quantitatively. Incorporating interdisciplinary knowledge from graph theory, information theory, measurement theory, and statistical techniques, it covers a wide range of quantitative graph-theoretical concepts and methods, including those pertaining to random graphs. Through its broad coverage, the book fills a gap in the contemporary literature of discrete and applied mathematics, computer science, systems biology, and related disciplines. Print ISBN: 978-1-4665-8451-8 June 2014, 6-1/8 x 9-1/4, 450 pp. Suggested Price: $89.95 / £57.99
Print ISBN: 978-1-4665-1478-2 eBook ISBN: 978-1-4665-1479-9 March 2013, 6-1/8 x 9-1/4, 301 pp. Suggested Price: $99.95 / £63.99
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Computational Biology / Mathematics for Biology & Medicine
Introduction to Biological Networks
77
Game-Theoretical Models in Biology Mark Broom City University, London, UK
Jan Rychtar University of North Carolina at Greensboro, USA Series: Chapman & Hall/CRC Mathematical & Computational Biology
Mathematics for Biology & Medicine 78
Covering the major topics of evolutionary game theory, this text presents both abstract and practical mathematical models of real biological situations. Suitable for readers studying and working at the interface of mathematics and the life sciences, it shows how evolutionary game theory is used in the modeling of diverse biological phenomena. The authors discuss the static aspects of game theory in a mathematically rigorous way that is appealing to mathematicians. In addition, they explore many applications of game theory to biology, making the text useful to biologists as well.
Modeling and Control for Micro/Nano Devices and Systems Edited by
Ning Xi, Mingjun Zhang, and Guangyong Li Series: Automation and Control Engineering, 54
The first to address this emerging field, this book provides experts’ cutting-edge knowledge of micro/ nanotechnology, energy, and bio-systems. The editors offer an integrated view from theory to practice, covering topics ranging from sensors to energy devices and control of biology systems in cellular and molecular levels. The book also features case studies for modeling of micro/nano devices and systems, and explains how the models can be used for control and optimization. Readers benefit from learning new techniques, and applying those techniques to their own research.
Print ISBN: 978-1-4398-5321-4 eBook ISBN: 978-1-4398-5322-1 March 2013, 6-1/8 x 9-1/4, 520 pp. Suggested Price: $79.95 / £39.99
Print ISBN: 978-1-4665-5405-4 November 2013, 6-1/8 x 9-1/4, 175 pp. Suggested Price: $139.95 / £89.00
An Introduction to Physical Oncology
Stochastic Dynamics for Systems Biology
Towards Transitional Application of Multiscale Cancer Modeling
Christian Mazza
Vittorio Cristini and Zhihui Wang University of New Mexico, Albuquerque, USA
This book provides a description of the rapid development of a new field, physical oncology, which aims at quantifying the role of physical transport processes over multiple scales in cancer growth. The book presents a theoretical multiscale modeling framework for the integration of processes spanning from molecular signaling, to individual and collective cellular behavior, and to complex spatiotemporal dynamics at the tissue and organ levels. This is followed by a detailed discussion for the incorporation of experimental and patient data into the modeling. Finally, multiscale modeling approaches are illustrated through several applications spanning from breast cancer and mammary gland development, to lymphoma and leukemia growth, to the investigation of biobarriers to chemotherapeutic drugs, and in particular to nanoparticle-based delivering strategies.
University of Fribourg, Switzerland
Michel Benaim Neuchatel University, Switzerland Series: Chapman & Hall/CRC Mathematical & Computational Biology, 54
This book describes the stochastic dynamics modeling of gene expression processes not only at the cell level but also at higher organization levels, such as in morphogenesis. The book is one of the first to provide a systematic study of the many models used in the life sciences. Designed as a reference for mathematical biologists, systems biologists, biophysicists, and biomedical engineers, it can also be used as a text in advanced courses and includes exercises. Print ISBN: 978-1-4665-1493-5 March 2014, 6 x 9, 264 pp. Suggested Price: $79.95 / £49.99
Print ISBN: 978-1-4665-5134-3 June 2014, 7 x 10, 300 pp. Suggested Price: $89.95 / £57.99
Textbook
An Introduction to Systems Biology Design Principles of Biological Circuits Uri Alon Weizmann Institute of Science, Rehovot, Israel Series: Chapman & Hall/CRC Mathematical & Computational Biology
Highlighting simple, recurring circuit elements that make up a network, this book presents current design principles that govern the structure and behavior of biological networks such as gene circuits. It provides a quantitative theory for which circuits are found in a given environment and a mathematical framework for understanding and designing biological circuits. Requiring only knowledge of basic mathematics, it includes a review of necessary background material and introduces the concepts, principles, and mathematical tools that will drive future developments in the field. Print ISBN: 978-1-58488-642-6 eBook ISBN: 978-1-4200-1143-2 July 2006, 7 x 10, 320 pp., Soft Cover Suggested Price: $65.95 / £41.99
Synthetic Gene Network Modeling, Analysis and Robust Design Methods Bor-Sen Chen National Tsing Hua University, Hsinchu, Taiwan
Yu-Chao Wang National Tsing Hua University, Hsinchu, Taiwan
This book develops a rational design and systematic approach to construct a gene network with desired behaviors. In order to achieve this goal, the registry of standard biological parts and experimental techniques are introduced at first. Then these biological components are characterized by a standard modeling method and collected in the component libraries, which can be efficiently reused in engineering synthetic gene networks. Based on the system theory, some design specifications are provided to engineer the synthetic gene networks to robustly track the desired trajectory by employing the component libraries. Print ISBN: 978-1-4665-9269-8 February 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $129.95 / £82.00
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Analysis of Capture-Recapture Data
Cesar Ariel Pinto
Byron J. T. Morgan
Old Dominion University, Norfolk, Virginia, USA
University of Kent, Canterbury, UK
Paul R. Garvey
Rachel S. McCrea
The MITRE Corporation, Bedford, Massachusetts, USA
University of Kent, Canterbury, UK
Series: Statistics: A Series of Textbooks and Monographs
Series: Chapman & Hall/CRC Interdisciplinary Statistics
Focusing on the modeling, analysis, and management of risk in today’s complex engineering enterprise systems, this book provides advanced methods for tackling risk problems at the enterprise level. The text presents a risk analytical framework for engineering enterprise systems and covers capability portfolio risk management, functional dependency network analysis, and extreme-event theory. It also discusses prioritization systems in highly networked enterprise environments and examines how to measure risks of extreme latencies in complex queuing networks.
Written for researchers and graduate students in statistics, demography, and the social sciences, this reference provides an overview of capture-recapture—the statistical methods used to estimate population size. It covers model development and examines the technicalities of model diagnostics, an often overlooked aspect in practice. The authors provide examples to demonstrate the statistical nuances that are encountered with complex modeling. They use real-world data sets throughout the text and include stand-alone software programs, such as R and WinBUGS. Chapters contain exercises to assist with reader assimilation of the material.
Print ISBN: 978-1-4398-2614-0 eBook ISBN: 978-1-4398-2615-7 October 2012, 6-1/8 x 9-1/4, 464 pp. Suggested Price: $104.95 / £66.99
Age-Period-Cohort Analysis
Print ISBN: 978-1-4398-3659-0 April 2014, 6-1/8 x 9-1/4, 256 pp. Suggested Price: $79.95 / £49.99
Textbook
New Models, Methods, and Empirical Applications
Analysis of Categorical Data with R
Yang Yang
Christopher R. Bilder
University of North Carolina, Chapel Hill, USA
Kenneth C. Land Duke University, Durham, North Carolina, USA
University of Nebraska, Lincoln, USA
Thomas M. Loughin Simon Fraser University, Surrey, British Columbia, Canada
Series: Chapman & Hall/CRC Interdisciplinary Statistics
Series: Chapman & Hall/CRC Texts in Statistical Science
This book explores the ways in which statistical models, methods, and research designs can be used to open new possibilities for APC analysis. Within a single, consistent HAPC-GLMM statistical modeling framework, the authors synthesize APC models and methods for three research designs: age-by-time period tables of population rates or proportions, repeated crosssection sample surveys, and accelerated longitudinal panel studies. They show how the empirical application of the models to various problems leads to many fascinating findings on how outcome variables develop along the age, period, and cohort dimensions.
Written for students and researchers in statistics and biostatistics, this book presents a modern introduction to categorical data analysis, with R integrated into the text as a data analysis method and a learning tool. The book includes many detailed worked examples to illustrate methods, with R code and data available for all of them. It also includes many exercises throughout the text and is supplemented by a solutions manual and website with code, data, and video lectures. Unlike other books on the subject, topics such as missing data and Bayesian methods are covered.
Print ISBN: 978-1-4665-0752-4 eBook ISBN: 978-1-4665-0753-1 February 2013, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $79.95 / £49.99
Print ISBN: 978-1-4398-5567-6 June 2014, 7 x 10, 416 pp. Suggested Price: $89.95 / £49.99
Analysis of Mixed Data Age-Period-Cohort Models Approaches and Analyses with Aggregate Data
Methods & Applications Edited by
Alexander R. de Leon University of Calgary, Alberta, Canada
Keumhee Carrière Chough
Robert M. O’Brien University of Oregon, Eugene, USA
University of Alberta, Edmonton, Canada
Series: Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences
A comprehensive source on mixed data analysis, Analysis of Mixed Data: Methods & Applications offers a complete and up-to-date introduction to and summary of the fundamental advances and developments in the field. It presents modern methods, and case studies are used extensively throughout the book to illustrate interesting applications from economics, medicine and health, marketing, and genetics. All chapters include illustrative examples, many drawn from real-life case studies, and ample cross-references between chapters are included to enable readers to connect the book’s various topics and research strands and to facilitate self-study.
One of the first to do so, this book integrates the major approaches to APC analysis for aggregate-level data, such as uniform crime reports, vital statistics, and census data. It connects the traditional methods of constrained estimation, estimation using cohort (or age or period) characteristics, estimable functions, the overidentification approach of Winship and Harding, variance decomposition, and a sufficient condition for age, period, or cohort effects. Print ISBN: 978-1-4665-5153-4 May 2014, 6 x 9, 224 pp. Suggested Price: $79.95 / £49.99
Statistics for Biological Science
Advanced Risk Analysis in Engineering Enterprise Systems
Print ISBN: 978-1-4398-8471-3 eBook ISBN: 978-1-4398-8472-0 January 2013, 7 x 10, 262 pp. Suggested Price: $89.95 / £57.99
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79
Analysis of Variance for Functional Data Jin-Ting Zhang National University of Singapore Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability, 127
Steven G. Heeringa, Brady T. West, and Patricia A. Berglund Series: Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences
Statistics for Biological Science
This self-contained book presents up-to-date hypothesis testing methods for functional data analysis. Useful for statistical researchers and practitioners analyzing functional data, it gives both a theoretical and applied treatment of functional data analysis supported by easy-to-use MATLAB® code. The book covers the reconstruction of functional observations, functional ANOVA, functional linear models with functional responses, ill-conditioned functional linear models, diagnostics of functional observations, heteroscedastic ANOVA for functional data, and testing equality of covariance functions. Data sets and MATLAB are available on the author’s website.
With many examples and exercises based on major realworld survey data sets, this book provides a practical statistical overview of the analysis of complex sample survey data. It presents many methods and models for survey data analysis, including the linear regression, generalized linear, Cox proportional hazards, and discrete time models. It also explores new developments in advanced statistical techniques, such as multilevel analysis of survey data. The authors show how design characteristics are easily incorporated into the statistical methods and software for survey estimation and inference. Although Stata is used for most examples in the text, other software code is also offered on the book’s website.
Print ISBN: 978-1-4398-6273-5 eBook ISBN: 978-1-4398-6274-2 June 2013, 6-1/8 x 9-1/4, 412 pp. Suggested Price: $99.95 / £63.99
Print ISBN: 978-1-4200-8066-7 eBook ISBN: 978-1-4200-8067-4 April 2010, 6-1/8 x 9-1/4, 487 pp. Suggested Price: $87.95 / £55.99
Textbook
The A-Z of Error-Free Research
Applied Categorical and Count Data Analysis Wan Tang, Hua He, and Xin M. Tu Series: Chapman & Hall/CRC Texts in Statistical Science
This self-contained text explains how to perform the statistical analysis of discrete data. It covers classic concepts and popular topics, such as contingency tables, logistic models, and Poisson regression models, along with modern areas that include models for zero-modified count outcomes, parametric and semiparametric longitudinal data analysis, reliability analysis, and methods for dealing with missing values. R, SAS, SPSS, and Stata programming codes are provided for all the examples, enabling readers to immediately experiment with the data in the examples.
80
Applied Survey Data Analysis
Phillip I. Good Consultant, Huntington Beach, California, USA
This practical book begins with an overview of when—and when not—to use statistics. It guides readers through the planning and data collection phases and presents various data analysis techniques, including methods for sample size determination. The author then covers techniques for developing models that provide a basis for future research. He also discusses reporting techniques to ensure research efforts get the proper credit. The book concludes with case-control and cohort studies. R code is included to implement the methods. Print ISBN: 978-1-4398-9737-9 August 2012, 5-1/2 x 8-1/2, 269 pp., Soft Cover Suggested Price: $52.95 / £33.99
Print ISBN: 978-1-4398-0624-1 eBook ISBN: 978-1-4398-0625-8 June 2012, 6-1/8 x 9-1/4, 384 pp. Suggested Price: $93.95 / £59.99
Textbook
Applied Nonparametric Statistical Methods
Bayesian Inference for Partially Identified Models
Fourth Edition
Exploring the Limits of Limited Data
Peter Sprent
Paul Gustafson
Dundee University, Scotland
University of British Columbia, Vancouver, Canada
Nigel C. Smeeton
Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability
Guy’s King & St. Thomas School of Medicine, London, UK Series: Chapman & Hall/CRC Texts in Statistical Science
While preserving the clear, accessible style of previous editions, this fourth edition reflects the latest developments in computer-intensive methods that deal with intractable analytical problems and unwieldy data sets. This edition summarizes relevant general statistical concepts and introduces basic ideas of nonparametric or distribution-free methods. Designed experiments, including those with factorial treatment structures, are now the focus of an entire chapter. The book also expands coverage on the analysis of survival data and the bootstrap method. The new final chapter focuses on important modern developments. With numerous exercises, the text offers the student edition of StatXact at a discounted price.
Many observational studies in epidemiology and other disciplines face inherent limitations in study design and data quality, such as selection bias, unobserved variables, and poorly measured variables. Accessible to statisticians and researchers from various disciplines, this book presents an overview of Bayesian inference in partially identified models. It includes many examples to illustrate the methods and provides R code for their implementation on the book’s website. The author also addresses a number of open questions to stimulate further research in this area. Print ISBN: 978-1-4398-6939-0 June 2014, 6-1/8 x 9-1/4, 256 pp. Suggested Price: $89.95 / £57.99
Print ISBN: 978-1-58488-701-0 March 2007, 6-1/8 x 9-1/4, 544 pp. Suggested Price: $98.95 / £62.99
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Textbook
Textbook
Bayesian Methods
Design and Analysis of Experiments with SAS
A Social and Behavioral Sciences Approach, Third Edition
John Lawson
Washington University, St. Louis, Missouri, USA
Series: Chapman & Hall/CRC Texts in Statistical Science
Series: Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences
This textbook covers both classical ideas in experimental design and the latest research topics. It clearly discusses the objectives of a research project that lead to an appropriate design choice, the practical aspects of creating a design and performing experiments, and the interpretation of computer data analysis results. Using SAS 9.2 to illustrate the construction of experimental designs and analysis of data, the author presents many applications from the pharmaceutical, agricultural, industrial chemicals, and machinery industries. SAS code and ancillaries are available on the author’s website.
This updated, bestselling book continues to be one of the only Bayesian statistics texts designed for social scientists. Incorporating new research and additional material, the third edition presents state-of-the-art guidance on Bayesian statistical computing. It emphasizes Markov chain Monte Carlo (MCMC) and computation with R and WinBUGS. Along with doubling the number of exercises, this edition covers time series, decision theory, nonparametric models, and mixture models. A solutions manual is available with qualifying course adoption. Print ISBN: 978-1-4398-6248-3 June 2014, 7 x 10, 700 pp. Suggested Price: $75.95 / £48.99
Print ISBN: 978-1-4200-6060-7 eBook ISBN: 978-1-4200-6064-5 May 2010, 6-1/8 x 9-1/4, 596 pp. Suggested Price: $104.95 / £69.99
Dynamic Documents with R and knitr
Textbook
Bayesian Methods for Data Analysis
Yihui Xie Iowa State University, Ames, USA
Third Edition
Series: Chapman & Hall/CRC The R Series
Bradley P. Carlin University of Minnesota, Minneapolis, USA
Thomas A. Louis Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA Series: Chapman & Hall/CRC Texts in Statistical Science
This proven text provides an accessible introduction to the foundations and applications of Bayesian analysis. Broadening its scope to nonstatisticians, this edition concentrates more on hierarchical Bayesian modeling as implemented via MCMC methods and related data analytic techniques. It contains a readerfriendly introduction to hierarchical statistical modeling, a new chapter on Bayesian design that emphasizes Bayesian clinical trials, a completely revised and expanded section on ranking and histogram estimation, and a new case study on infectious disease modeling and the 1918 flu epidemic. This edition includes new data examples, corresponding R and WinBUGS code, and exercises. Print ISBN: 978-1-58488-697-6 eBook ISBN: 978-1-4398-8934-3 June 2008, 6-1/8 x 9-1/4, 552 pp. Suggested Price: $79.95 / £51.99
Suitable for both beginners and advanced users, this book shows you how to write reports in simple languages such as Markdown. The reports range from homework, projects, exams, books, blogs, and web pages to any documents related to statistical graphics, computing, and data analysis. While familiarity with LaTeX and HTML is helpful, the book requires no prior experience with advanced programs or languages. For beginners, the text provides enough features to get started on basic applications. For power users, the last several chapters enable an understanding of the extensibility of the knitr package. Print ISBN: 978-1-4822-0353-0 eBook ISBN: 978-1-4822-0354-7 July 2013, 6-1/8 x 9-1/4, 216 pp., Soft Cover Suggested Price: $59.95 / £38.99
81 Textbook
Essential Statistics
Textbook
Fourth Edition
Design and Analysis of Experiments with R
D.G. Rees Oxford Brookes University, UK
Edited by
John Lawson Brigham Young University, Provo, Utah, USA Series: Chapman & Hall/CRC Texts in Statistical Science
One of the first texts to use R to illustrate the construction of experimental designs and analysis of data, this book covers both classical ideas in experimental design and the latest research topics. It clearly discusses the objectives of a research project that lead to an appropriate design choice, the practical aspects of creating a design and performing experiments, and the interpretation of the results of computer data analysis. It also includes many applications from the pharmaceutical, agricultural, industrial chemicals, and machinery industries. A solutions manual is available for qualifying instructors.
Statistics for Biological Science
Brigham Young University, Provo, Utah, USA
Jeff Gill
An introductory text for students taking a first course in statistics, Essential Statistics, Fourth Edition thoroughly updates and enhances the hugely successful third edition. It presents new information on modern statistical techniques, such as Analysis of Variance, and software such as Minitab. The author writes in his trademark easy-to-follow style and emphasizes the principles and assumptions underlying the statistical methods. Keeping complex mathematical theory to a minimum, he presents a wealth of fully explained, worked examples. End-of-chapter worksheets relate to a variety of fields and illustrate the relevance of the methods to a broad range of disciplines. Print ISBN: 978-1-58488-007-3 December 2000, 6-1/8 x 9-1/4, 384 pp., Soft Cover Suggested Price: $75.95 / £48.99
Print ISBN: 978-1-4398-6813-3 June 2014, 6-1/8 x 9-1/4, 596 pp. Suggested Price: $99.95 / £63.99
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Event History Analysis with R Göran Broström Professor emeritus of statistics, Centre for Population Studies, Umeå University, Sweden Series: Chapman & Hall/CRC The R Series
Statistics for Biological Science
With an emphasis on social science applications, this book presents an introduction to survival and event history analysis. It focuses on practical applications in the fields of demography, epidemiology, and econometrics. The text includes a wide range of real examples, with data available online and supported by a dedicated R package for performing all of the analyses. Keeping mathematical details to a minimum, the author covers key topics, including both discrete and continuous time data, parametric proportional hazards, and accelerated failure times. He also describes how to use methods that are not available in other software for survival analysis.
Stef van Buuren TNO Quality of Life, Leiden, The Netherlands Series: Chapman & Hall/CRC Interdisciplinary Statistics
A practical guide for handling missing data, this book provides a flexible and accessible framework for multiple imputation along with strategies for obtaining effective solutions to these problems. The text is supported by many examples using real data taken from the author’s vast research involving missing data. All of the analyses can be replicated in R using the dedicated package MICE, which was developed by the author. Topics covered include multiple imputation, multivariate and univariate missing data, as well as issues of measurement, selection, and longitudinal data.
Print ISBN: 978-1-4398-3164-9 eBook ISBN: 978-1-4398-3167-0 April 2012, 6-1/8 x 9-1/4, 236 pp. Suggested Price: $83.95 / £51.99
Print ISBN: 978-1-4398-6824-9 eBook ISBN: 978-1-4398-6825-6 March 2012, 6-1/8 x 9-1/4, 342 pp. Suggested Price: $93.95 / £59.99
Textbook
Textbook
Exercises and Solutions in Statistical Theory
Foundational and Applied Statistics for Biologists Using R
Lawrence L. Kupper, Brian. H Neelon, and Sean M. O’Brien
Ken A. Aho
Series: Chapman & Hall/CRC Texts in Statistical Science
Taking a biological perspective, this text provides an introduction to foundational topics in science, probability, and mathematical statistics for advanced undergraduate and graduate students in biology and related fields. It offers comprehensive background material in probability and mathematical statistics, emphasizing Bayesian methods and biological applications throughout. The author discusses relevant issues in the philosophy of science as well as the design of effective experiments. He also uses an R package specifically developed to demonstrate ideas presented in the book.
This book helps readers obtain an in-depth understanding of statistical theory by working on and reviewing solutions to interesting and challenging exercises of practical importance. Unlike similar books, this one incorporates many exercises that apply to real-world settings and provides much more thorough solutions. The exercises and selected detailed solutions cover from basic probability theory through to the theory of statistical inference. By mastering the theoretical statistical strategies necessary to solve the exercises, readers will be prepared to successfully study even higher-level statistical theory.
82
Flexible Imputation of Missing Data
Print ISBN: 978-1-4665-7289-8 eBook ISBN: 978-1-4665-7291-1 June 2013, 6-1/8 x 9-1/4, 388 pp., Soft Cover Suggested Price: $59.95 / £38.99
Idaho State University, Pocatello, USA
Print ISBN: 978-1-4398-7338-0 December 2013, 7 x 10, 616 pp. Suggested Price: $69.95 / £44.99
Textbook
Textbook
Extending the Linear Model with R
Generalized Additive Models
Generalized Linear, Mixed Effects and Nonparametric Regression Models
Simon Wood
Julian J. Faraway University of Bath, UK Series: Chapman & Hall/CRC Texts in Statistical Science
Linear models form the foundation of a vast range of statistical methodologies. This volume surveys the techniques that grow from the regression model, presenting three extensions to that framework: generalized linear models, mixed effect models, and nonparametric regression models. It provides a wellstocked toolbox of methodologies, and with its unique presentation of these very modern statistical techniques, holds the potential to break new ground in the way graduate-level courses in this area are taught. Print ISBN: 978-1-58488-424-8 eBook ISBN: 978-0-203-49228-4 December 2005, 6-1/8 x 9-1/4, 312 pp. Suggested Price: $98.95 / £51.99
An Introduction with R University of Bath, UK Series: Chapman & Hall/CRC Texts in Statistical Science
Generalized Additive Models: An Introduction with R imparts a thorough understanding of the theory and practical applications of GAMs and related advanced models, enabling informed use of these flexible tools. The author’s approach is based on a framework of penalized regression splines, and he builds the necessary foundation through motivating chapters on linear and generalized linear models. Use of the freely available R software helps explain the theory and illustrates the practicalities of linear, generalized linear, and generalized additive models, as well as their mixed effect extensions. An R package containing the featured datasets is freely available on the Internet. Print ISBN: 978-1-58488-474-3 February 2006, 6-1/8 x 9-1/4, 410 pp. Suggested Price: $104.95 / £65.99
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Generalized Estimating Equations
Handbook of Markov Chain Monte Carlo
Second Edition
Edited by
University of South Carolina, Columbia, USA
Joseph M. Hilbe California Institute of Technology, Pasadena, and Arizona State University, Tempe, USA
This second edition of a bestseller incorporates comments and suggestions from a variety of sources, including the Statistics.com course on longitudinal and panel models taught by the authors. Along with doubling the number of end-of-chapter exercises, this edition offers more thorough coverage of hypothesis testing and diagnostics, expands discussion of various models associated with GEE, and provides a new presentation of model selection procedures. Numerous examples are employed throughout the text, along with the software code used to create, run, and evaluate the models being examined. Print ISBN: 978-1-4398-8113-2 eBook ISBN: 978-1-4398-8114-9 December 2012, 6-1/8 x 9-1/4, 277 pp. Suggested Price: $93.95 / £59.99
Textbook
Generalized Linear Models for Categorical and Continuous Limited Dependent Variables Michael Smithson The Australian National University, Canberra
Edgar C. Merkle University of Missouri, Columbia, USA Series: Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences
Designed for graduate students and researchers in the behavioral, social, health, and medical sciences, this text employs generalized linear models, including mixed models, for categorical and limited dependent variables. Categorical variables include both nominal and ordinal variables. Discrete or continuous limited dependent variables have restricted support, whether through censorship or truncation or by their nature. The book incorporates examples of truncated counts, censored continuous variables, and doubly bounded continuous variables, such as percentages.
Steve Brooks, Andrew Gelman, Galin Jones, and Xiao-Li Meng Series: Chapman & Hall/CRC Handbooks of Modern Statistical Methods
Handbook of Markov Chain Monte Carlo brings together the major advances that have occurred in recent years while incorporating enough introductory material for new users of MCMC. Along with thorough coverage of the theoretical foundations and algorithmic and computational methodology, this comprehensive handbook includes substantial realistic case studies from a variety of disciplines. These case studies demonstrate the application of MCMC methods and serve as a series of templates for the construction, implementation, and choice of MCMC methodology. Print ISBN: 978-1-4200-7941-8 eBook ISBN: 978-1-4200-7942-5 May 2011, 7 x 10, 619 pp. Suggested Price: $109.95 / £69.99
Handbook of Missing Data Methodology Geert Molenberghs, Garrett Fitzmaurice, Michael G. Kenward, Anastasios Tsiatis, and Geert Verbeke Series: Chapman & Hall/CRC Handbooks of Modern Statistical Methods
Written by a team of leading researchers in the field, this handbook presents a comprehensive overview of the state of the art in the theory and applications of missing data analysis. It covers historical developments, Bayesian and likelihood methods, semiparametric methods, multiple imputation, sensitivity analysis, and other special topics. Accessible to graduate students and researchers, each chapter provides sufficient background material, worked examples, case studies, and software, where applicable. Print ISBN: 978-1-4398-5461-7 June 2014, 7 x 10, 672 pp. Suggested Price: $99.95 / £63.99
Print ISBN: 978-1-4665-5173-2 eBook ISBN: 978-1-4665-5175-6 September 2013, 6-1/8 x 9-1/4, 308 pp. Suggested Price: $89.95 / £57.99
83 Handbook of Spatial Statistics
A Handbook of Applied Statistics in Pharmacology
Edited by
Katsumi Kobayashi
Series: Chapman & Hall/CRC Handbooks of Modern Statistical Methods
National Institute of Technology and Evaluation, Tokyo, Japan
K. Sadasivan Pillai Frontier Life Sciences Services, Chennai, India
Statistics plays an important role in pharmacology and related subjects such as toxicology and drug discovery and development. Improper statistical tool selection for analyzing the data obtained from studies may result in wrongful interpretation of the performance or safety of drugs. This book communicates statistical tools in simple language. The examples used are similar to those that scientists encounter regularly in their research area. The authors provide cognitive clues for selection of appropriate tools to analyze the data obtained from the studies and explain how to interpret the result of the statistical analysis. Print ISBN: 978-1-57808-752-5 eBook ISBN: 978-1-4665-1540-6 October 2012, 6-1/8 x 9-1/4, 230 pp. Suggested Price: $93.95 / £59.99
Statistics for Biological Science
James W. Hardin
Alan E. Gelfand, Peter Diggle, Peter Guttorp, and Montserrat Fuentes
Based on the work of prominent researchers, this handbook provides broad, thorough coverage of this vibrant area, from historical to contemporary topics. It explores the modeling advances, computational approaches, and methodology that have emerged in recent years. The book focuses on continuous and discrete spatial variation, spatial point patterns, and spatio-temporal processes. It also covers multivariate spatial process models, spatial aggregation, spatial misalignment, and spatial gradients in depth. The theory and applications are illustrated with many real-world data examples. Print ISBN: 978-1-4200-7287-7 eBook ISBN: 978-1-4200-7288-4 March 2010, 7 x 10, 619 pp. Suggested Price: $115.95 / £72.99
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A Handbook of Statistical Analyses using R
A Handbook of Statistical Graphics Using SAS
Third Edition
Geoff Der
Brian S. Everitt Professor Emeritus, Institute of Psychiatry, King’s College, London, UK
Torsten Hothorn Universitaet Zuerich, Switzerland
Statistics for Biological Science
One of the leading references on analyzing data using R, this third edition has been updated with much more descriptive text to support the computer code. Along with many new references, datasets, and exercises, this edition also includes new chapters on Bayesian methods, missing data and imputation, and spatial methods. The book is supported by an R package and provides all the data and code online. Print ISBN: 978-1-4822-0458-2 June 2014, 6-1/8 x 9-1/4, 425 pp., Soft Cover Suggested Price: $64.95 / £39.99
A Handbook of Statistical Analyses using SAS Third Edition Geoff Der University of Glasgow, Scotland
Brian S. Everitt
84
University of Glasgow, Scotland
Brian S. Everitt Professor Emeritus, Institute of Psychiatry, King’s College, London (Retired), UK
This handbook shows how to use SAS to create many different types of useful statistical graphics for exploring data and diagnosing fitted models. The book focuses on the relatively new SAS ODS graphics, including graphs that are produced routinely via ODS and more tailored graphics. Each chapter deals graphically with several sets of data from a wide variety of areas and includes exercises. Print ISBN: 978-1-4665-9903-1 April 2014, 6-1/8 x 9-1/4, 250 pp. Suggested Price: $69.95 / £44.99
Hidden Markov Models for Time Series An Introduction Using R Walter Zucchini University of Gottingen, Germany
Iain L. MacDonald University of Cape Town, South Africa
King’s College, London, UK
Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability, 110
Remaining the go-to resource for learning how to use SAS for many kinds of statistical analysis, this third edition of a bestseller explains how to conduct a range of statistical analyses using the latest version of SAS. It illustrates each type of analysis with numerous real-world data examples, such as environmental causes of diseases, hypertension treatment, and gastric cancer treatment. This edition presents the new graphics procedures of SAS 9.2. It also includes more end-of-chapter exercises and selected answers in the appendix, along with a solutions manual that provides SAS code, output, and comments. The SAS programs and data sets used in the book are available online.
This book illustrates the wonderful flexibility of HMMs as general-purpose models for time series data. It presents an accessible overview of HMMs for analyzing time series data, from continuous-valued, circular, and multivariate series to binary data, bounded and unbounded counts, and categorical observations. It explores a variety of applications in animal behavior, finance, epidemiology, climatology, and sociology. The authors discuss how to employ the freely available computing environment R to carry out computations for parameter estimation, model selection and checking, decoding, and forecasting. They provide all of the data sets analyzed in the text online.
Print ISBN: 978-1-58488-784-3 December 2008, 6-1/8 x 9-1/4, 392 pp., Soft Cover Suggested Price: $68.95 / £43.99
Print ISBN: 978-1-58488-573-3 eBook ISBN: 978-1-4200-1089-3 April 2009, 6 x 9, 288 pp. Suggested Price: $91.95 / £55.99
Handbook of Statistical Analyses Using Stata
Implementing Reproducible Research
Fourth Edition
Edited by
Brian S. Everitt King’s College, London, UK
Victoria Stodden, Friedrich Leisch, and Roger D. Peng
Sophia Rabe-Hesketh
Series: Chapman & Hall/CRC The R Series
University of California, Berkeley, USA
In many of today’s research fields, including biomedicine, computational tools are increasingly being used so that the results can be reproduced. Researchers are now encouraged to incorporate software, data, and code in their academic papers so that others can replicate their research results. Edited by three pioneers in this emerging area, this book is the first one to explore this groundbreaking topic. It presents various computational tools useful in research, including cloud computing, data repositories, virtual machines, R’s Sweave function, XML-based programming, and more. It also discusses legal issues and case studies.
Fully updated, the fourth edition of this highly acclaimed and perpetually bestselling text demonstrates how a wide variety of statistical analyses, including descriptive statistics, graphics, and model estimation and diagnostics, can be performed using Stata version 9. The authors present many of Stata’s novel features, including a new mixed-models estimation command and a new matrix language. This edition also contains additional exercises that use various data sets and numerous examples of real-life data, enabling a better understanding of the methodology. The book offers selected solutions in an appendix as well as a solutions manual with qualifying course adoptions. Print ISBN: 978-1-58488-756-0 eBook ISBN: 978-1-4665-8057-2 November 2006, 6 x 9, 352 pp., Soft Cover Suggested Price: $75.95 / £48.99
Print ISBN: 978-1-4665-6159-5 March 2014, 6-1/8 x 9-1/4, 448 pp. Suggested Price: $79.95 / £49.99
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Non-Randomized Response Techniques for Sensitive Questions in Surveys Guo-Liang Tian
Textbook
Introduction to Statistical Data Analysis for the Life Sciences Claus Thorn Ekstrom Helle Sørensen
The University of Hong Kong
University of Copenhagen, Denmark
Man-Lai Tang
Developed from the authors’ courses at the University of Copenhagen, this text provides a computational toolbox that enables readers to perform actual analysis for real data sets and gain the confidence and skills to undertake progressively more sophisticated analyses. Though accessible with any statistical software, the text encourages a reliance on R. The authors provide a short tutorial for those new to the software and include R commands and output at the end of each chapter. Data sets are available on a supporting website.
Hong Kong Baptist University Series: Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences
A self-contained, systematic introduction, this book shows you how to draw valid statistical inferences from survey data with sensitive characteristics. It guides you in applying the non-randomized response approach in surveys and new nonrandomized response designs. The techniques covered integrate the strengths of existing approaches, including randomized response models, incomplete categorical data design, the EM algorithm, the bootstrap method, and the data augmentation algorithm. All R codes for the examples are available online. Print ISBN: 978-1-4398-5533-1 eBook ISBN: 978-1-4398-5534-8 August 2013, 6-1/8 x 9-1/4, 319 pp. Suggested Price: $89.95 / £57.99
Introduction to Ecological Sampling Edited by
Bryan F.J. Manly Western EcoSystem Technology, Inc., Laramie, Wyoming, USA
Jorge A. Navarro Alberto Universidad Autonoma Deucatan, Merida, Yucatan, Mexico Series: Chapman & Hall/CRC Applied Environmental Statistics
Accessible to ecological researchers, this book is the first to introduce ecological sampling methods from a statistical viewpoint. It starts with classic random sampling methods and then covers more advanced forms of sampling, including adaptive, line transect, and plotless sampling. It also describes trend analysis, resource selection, and mark-recapture methods. The book presents the necessary theory but mainly focuses on showing readers how to apply the methods, incorporating many examples and case studies as well as software.
Print ISBN: 978-1-4398-2555-6 eBook ISBN: 978-1-4398-2556-3 August 2010, 6-1/8 x 9-1/4, 427 pp., Soft Cover Suggested Price: $75.95 / £35.99
Linear Mixed Models A Practical Guide Using Statistical Software Brady T. West, Kathleen B. Welch, and Andrzej T Galecki This easy-to-use resource provides a clear explanation of mixed modeling techniques and theories and demonstrates the use of popular statistical software procedures for fitting linear mixed models (LMMs). The authors fit LMMs based on both general and hierarchical model specifications, develop the modelbuilding process step-by-step, and demonstrate the estimation, testing, and interpretation of fixed-effect parameters and covariance parameters associated with random effects. These concepts are illustrated through examples of realworld data sets using R, SAS, SPSS, HLM, and Stata that enable comparison of model fitting options and results across the software procedures. A supporting website provides software code and the data sets discussed in the book.
Print ISBN: 978-1-4665-5514-3 June 2014, 6-1/8 x 9-1/4, 200 pp. Suggested Price: $89.95 / £57.99
Print ISBN: 978-1-58488-480-4 eBook ISBN: 978-1-4200-1043-5 November 2006, 7 x 10, 376 pp. Suggested Price: $104.95 / £65.99
Textbook
Textbook
An Introduction to Generalized Linear Models
Linear Models with R
Third Edition
Julian J. Faraway University of Bath, UK Series: Chapman & Hall/CRC Texts in Statistical Science
Annette J. Dobson University of Queensland, Herston, Australia
Adrian Barnett Queensland University of Technology, Kelvin Grove, Australia Series: Chapman & Hall/CRC Texts in Statistical Science
Updated with Stata, R, and WinBUGS code as well as three new chapters on Bayesian analysis, this new edition of a bestseller continues to provide a cohesive framework for statistical modeling. Emphasizing numerical and graphical methods, it enables readers to understand the unifying structure that underpins GLMs. The text discusses common concepts and principles of advanced GLMs, including nominal and ordinal regression, survival analysis, and longitudinal analysis. It contains numerous examples from business, medicine, engineering, and the social sciences and offers the data sets and solutions to the exercises online.
The first book that directly uses R to teach data analysis, this text focuses on the practice of regression and analysis of variance. It demonstrates the different methods available and in which situations each one applies. The book covers the basics of estimation, missing data, factorial designs, and block designs and also includes discussion on topics rarely addressed in books of this type, such as model uncertainty. The presentation incorporates examples that clarify both the use of each technique and the conclusions one can draw from the results. All of the data sets used in the book are available for download online. Print ISBN: 978-1-58488-425-5 eBook ISBN: 978-1-4822-2837-3 August 2004, 6-1/8 x 9-1/4, 240 pp. Suggested Price: $96.95 / £51.99
Print ISBN: 978-1-58488-950-2 eBook ISBN: 978-1-4398-8919-0 May 2008, 6-1/8 x 9-1/4, 320 pp., Soft Cover Suggested Price: $71.95 / £43.99
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Statistics for Biological Science
Incomplete Categorical Data Design
85
Textbook
Textbook
Logistic Regression Models
Practical Multivariate Analysis
Joseph M. Hilbe
Fifth Edition
California Institute of Technology, Pasadena, and Arizona State University, Tempe, USA Series: Chapman & Hall/CRC Texts in Statistical Science
Statistics for Biological Science
This text presents an overview of the full range of logistic models, including binary, proportional, ordered, and categorical response regression procedures. It illustrates how to apply the models to medical, health, environmental/ecological, physical, and social science data. Stata is used to develop, evaluate, and display most models while R code is given at the end of most chapters. The author examines the theoretical foundation of the models and describes how each type of model is established, interpreted, and evaluated as to its goodness of fit. Example data sets are available online in various formats and a solutions manual is available upon qualifying course adoption. Print ISBN: 978-1-4200-7575-5 eBook ISBN: 978-1-4398-8960-2 May 2009, 6-1/8 x 9-1/4, 656 pp. Suggested Price: $91.95 / £58.99
Series: Chapman & Hall/CRC Texts in Statistical Science
Taking into account novel multivariate analyses as well as new options for many standard methods, this renamed, new edition shows readers how to perform multivariate statistical analyses and understand the results. For each of the techniques presented, the authors use the most recent software versions available, including R, and discuss the most modern ways of performing the analysis. Along with more problems and data sets, this fifth edition includes a new chapter on regression of correlated outcomes. Data sets and code are available for download online. Print ISBN: 978-1-4398-1680-6 eBook ISBN: 978-1-4398-9202-2 July 2011, 6-1/8 x 9-1/4, 537 pp. Suggested Price: $98.95 / £48.99
Methods of Statistical Model Estimation
Reproducible Research with R and RStudio
Joseph M. Hilbe
Christopher Gandrud
California Institute of Technology, Pasadena, and Arizona State University, Tempe, USA
Hertie School of Governance, Berlin, Germany
Andrew P. Robinson University of Melbourne, Parkville, Australia
This book examines the most important and popular methods used to estimate parameters for statistical models and provide informative model summary statistics. Designed for R users, the book is also ideal for anyone wanting to better understand the algorithms used for statistical model fitting. It presents algorithms for the estimation of a variety of useful regression procedures using maximum likelihood estimation, iteratively reweighted least squares regression, the EM algorithm, and MCMC sampling. Fully developed, working R code is constructed for each method.
86
Abdelmonem Afifi, Susanne May, and Virginia A. Clark
Print ISBN: 978-1-4398-5802-8 eBook ISBN: 978-1-4398-5803-5 May 2013, 6-1/8 x 9-1/4, 255 pp. Suggested Price: $89.95 / £57.99
Textbook
Multivariate Statistical Methods A Primer, Third Edition Bryan F.J. Manly Western EcoSystem Technology, Inc., Laramie, Wyoming, USA
The third edition of this bestseller retains the author’s trademark clear, concise style and focus on examples in the biological and environmental sciences. Topics include the material of multivariate analysis, matrix algebra, displaying multivariate data, and tests of significance with multivariate data. The book also explores measuring and testing multivariate distances; principal components and analysis; and factor, discriminant function, cluster, and canonical correlation analysis. Multidimensional scaling and ordination round out the coverage. The book includes an appendix comparing and contrasting various statistical software packages, such as Stata, Statistica, SAS, and Genstat. Print ISBN: 978-1-58488-414-9 July 2004, 6-1/8 x 9-1/4, 224 pp., Soft Cover Suggested Price: $68.95 / £43.99
Series: Chapman & Hall/CRC The R Series
Bringing together computational research tools in one accessible source, this book guides you in creating dynamic and highly reproducible research. Whether you’re an advanced user or just getting started with tools such as R and LaTeX, the book saves you time searching for information and helps you successfully carry out computational research. It provides a practical reproducible research workflow for gathering and analyzing data as well as dynamically presenting results in print and on the web. Supplementary materials are available on the author’s website. Print ISBN: 978-1-4665-7284-3 eBook ISBN: 978-1-4665-7285-0 July 2013, 6-1/8 x 9-1/4, 294 pp., Soft Cover Suggested Price: $69.95 / £44.99
Richly Parameterized Linear Models Additive, Time Series, and Spatial Models Using Random Effects James S. Hodges University of Minnesota, Minneapolis, USA Series: Chapman & Hall/CRC Texts in Statistical Science
Using mixed linear models to analyze data often leads to results that are mysterious, inconvenient, or wrong. Further compounding the problem, statisticians lack a cohesive resource to acquire a systematic, theorybased understanding of models with random effects. This book takes a first step in developing a full theory of richly parameterized models, which would allow statisticians to better understand their analysis results. It examines what is known and unknown about mixed linear models and identifies research opportunities. Supporting materials are available on the author’s website. Print ISBN: 978-1-4398-6683-2 November 2013, 6-1/8 x 9-1/4, 469 pp. Suggested Price: $89.95 / £57.99
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Rabindra Nath Das
Statistical Analysis of Questionnaires A Unified Approach Based on R and Stata
The University of Burdwan, India
Francesco Bartolucci
There are many gaps in the existing literature of robust response surface designs (RSM) that need to be filled to solve real-life problems. This book presents the gaps and their solutions. The author proposes new concepts of RSM, along with the relevant regression analysis and positive data analysis techniques, and aims to remove many RSM limitations. Among a wide range of topics, the text covers applications of correlated regression analysis techniques in block design analysis, robust first and second order rotatable and optimal designs for normally distributed responses, as well as lifetime responses having log-normal, exponential, gamma and Weibull distributions.
University of Perugia, Italy
Print ISBN: 978-1-4665-0677-0 April 2014, 6-1/8 x 9-1/4, 425 pp. Suggested Price: $89.95 / £57.99
Silvia Bacci Michela Gnaldi Series: Chapman & Hall/CRC Interdisciplinary Statistics
Mirroring the growing interest and use of statistical methods and software in education, health, and marketing, this book focuses on the statistical methods used to analyze and validate questionnaires adopted in these fields. The book features an applied approach to conducting testing and measurement in the three mentioned fields. The chapters build from foundations of classical measurement theory, test reliability, validity and scaling, through Item Response Theory (IRT) fundamentals, IRT for dichotomous and polytomous items, and the most recent IRT extensions. Print ISBN: 978-1-4665-6849-5 June 2014, 6-1/8 x 9-1/4, 300 pp. Suggested Price: $89.95 / £57.99
SAS and R
Textbook
Data Management, Statistical Analysis, and Graphics, Second Edition
Maria L. Rizzo
Ken Kleinman
Statistical Computing with R Bowling Green State University, Ohio, USA Series: Chapman & Hall/CRC The R Series
This widely praised book shows how equivalent statistical methods can be applied in either SAS or R, enabling users of each software package to learn how to apply the methods in the other. The book covers data management, simple statistical procedures, modeling, regression, and graphics. This second edition includes new entries on various statistical procedures. It also presents many new examples in a number of new chapters covering simulation, probability, statistics, mathematics/computing, and graphics.
This text covers the traditional core material of computational statistics, with an emphasis on using the R language via an examples-based approach. An excellent tutorial on R programming techniques used in practical computational problems, it illustrates every algorithm with at least one fully implemented example coded in R. The book also offers the source code for all examples online and contains numerous exercises. Key topics covered include the simulation of random variables from probability distributions, the visualization of multivariate data, Monte Carlo integration and variance reduction methods, Monte Carlo methods in inference, bootstrap and jackknife, MCMC methods, and density estimation.
Print ISBN: 978-1-4665-8449-5 April 2014, 6-1/8 x 9-1/4, 425 pp. Suggested Price: $79.95 / £49.99
Print ISBN: 978-1-58488-545-0 November 2007, 6-1/8 x 9-1/4, 416 pp. Suggested Price: $99.95 / £45.99
Stated Preference Methods Using R
Textbook
Hideo Aizaki
An Integrated Approach, Second Edition
Harvard University, Boston, Massachusetts, USA
Nicholas. J Horton Amherst College, Massachusetts, USA
Institute for Rural Engineering, Ibaraki, Japan
Tomoaki Nakatani
Statistical Inference
Rakuno Gakuen University, Hokkaido, Japan
Helio S. Migon Dani Gamerman Francisco Louzada-Neto
Series: Chapman & Hall/CRC The R Series
Series: Chapman & Hall/CRC Texts in Statistical Science
The quantitative measurement of individual preferences is essential, allowing us to understand social phenomena and derive appropriate policies and business inferences. Suitable for applied statisticians and empirical researchers, this book helps readers select the best method for such measurement from the many econometric methods available. Providing a practical understanding of these methods, the authors present the theoretical foundations of each method together with worked examples to illustrate their application in various fields, notably empirical economics and market research. R is used to implement all methods, with code, packages, and data sets available online.
Unique in its presentation of topics from both classical and Bayesian perspectives, this second edition balances both sides elegantly and describes the relative strengths and weaknesses of the different approaches in each case. It covers all the key topics of standard inference courses, including point and interval estimation, hypothesis testing, prediction, approximation, and linear models. Along with real data examples and exercises for self-study, this edition offers numerous updates that reflect recent developments.
Hokkaido University, Japan
Kazuo Sato
Print ISBN: 978-1-4398-9047-9 June 2014, 6-1/8 x 9-1/4, 224 pp. Suggested Price: $79.95 / £49.99
Print ISBN: 978-1-4398-7880-4 May 2014, 6-1/8 x 9-1/4, 320 pp. Suggested Price: $89.95 / £57.99
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Statistics for Biological Science
Robust Response Surfaces, Regression, and Positive Data Analyses
87
Textbook
Statistical Methods for Handling Incomplete Data
Statistics for Biological Science / General References 88
Jae Kwang Kim Jun Shao
Time Series Modeling of Neuroscience Data Tohru Ozaki Institute of Statistical Mathematics, Tokyo, Japan Series: Chapman & Hall/CRC Interdisciplinary Statistics
Along with many examples, this text covers the most upto-date statistical theories and computational methods for analyzing incomplete data. It presents a thorough treatment of statistical theories of likelihood-based inference with missing data. It also discusses numerous computational techniques and theories on imputation and extensively covers methods involving propensity score weighting, nonignorable missing data, longitudinal missing data, survey sampling, and statistical matching. Some of the research ideas introduced can be developed further for specific applications. Print ISBN: 978-1-4398-4963-7 eBook ISBN: 978-1-4398-4964-4 July 2013, 6-1/8 x 9-1/4, 223 pp. Suggested Price: $89.95 / £57.99
Textbook
Stochastic Modeling and Mathematical Statistics A Text for Statisticians and Quantitative Scientists Francisco J. Samaniego University of California, Davis, USA Series: Chapman & Hall/CRC Texts in Statistical Science
This book is intended as a text for a two-quarter or two-semester post-calculus introduction to probability and mathematical statistics for undergraduate students in their junior or senior year, and also for graduate students in the quantitative sciences (e.g., agriculture, computer science, ecology, economics, engineering, epidemiology, genetics, psychology, and many others). The book designed to effectively serve two different audiences (a) majors and minors in mathematics and statistics and (b) students in quantitative disciplines with the appropriate mathematical background and with a serious interest of understanding probability and statistics at the foundational level. Print ISBN: 978-1-4665-6046-8 January 2014, 7 x 10, 624 pp. Suggested Price: $99.95 / £49.99
Theory of Factorial Design Single- and Multi-Stratum Experiments Ching-Shui Cheng University of California, Berkeley, USA and Academia Sinica, Taiwan Series: Chapman & Hall/CRC Monographs on Statistics & Applied Probability, 1
This self-contained book provides a rigorous, systematic, and up-to-date treatment of the modern theory of factorial design. It covers the general theory of multi-stratum factorial design, a design key for constructing factorial designs, new construction methods for resolution IV designs, and some results on their structures taken from the literature of projective geometry. Numerous examples, mainly from engineering and agriculture, illustrate the methods and exercises in each chapter enable the book to be used for self-study or in a special topics course. Print ISBN: 978-1-4665-0557-5 December 2013, 6-1/8 x 9-1/4, 409 pp. Suggested Price: $99.95 / £63.99
Due to recent advances in methodology that offer significant improvements over conventional methods, there is increasing interest in the use of time series models for the study of neuroscience data such as EEG, MEG, fMRI, and NIRS. This book presents an overview of time series models for the study of neuroscience data. Accessible to applied statisticians as well as quantitatively trained neuroscientists, the book is supported by many real examples to illustrate the methods and provides useful instructions for computational problems, enabling readers to develop their own computational toolbox to apply the methods to real data. Print ISBN: 978-1-4200-9460-2 eBook ISBN: 978-1-4200-9461-9 January 2012, 6-1/8 x 9-1/4, 574 pp. Suggested Price: $104.95 / £66.99
Comparative Anatomy and Phylogeny of Primate Muscles and Human Evolution Rui Diogo Howard University College of Medicine, Washington DC, USA
Bernard A. Wood George Washington University, Washington DC, USA
The combined anatomical materials provided in this book point out that modern humans have fewer head, neck, pectoral and upper limb muscles than most other living primates, but are consistent with the proposal that facial and vocal communication and specialized thumb movements have probably played an important role in recent human evolution. This book will be of interest to primatologists, comparative anatomists, functional morphologists, zoologists, physical anthropologists, and systematicians, as well as to medical students, physicians, and researchers interested in understanding the origin, evolution, homology, and variations of the muscles of modern humans. Print ISBN: 978-1-57808-767-9 eBook ISBN: 978-1-4398-8336-5 January 2012, 7 x 10, 906 pp. Suggested Price: $210.00 / £133.00
CRC Handbook of Chemistry and Physics 95th Edition Edited by
William M. Haynes National Institute of Standards and Technology, Boulder, Colorado, USA
Proudly serving the scientific community for over a century, this 95th edition is an update of a classic reference mirrors the growth and direction of science for a century. This venerable work continues to be the most accessed and respected scientific reference in the world. An authoritative resource consisting of tables of data, its usefulness spans every discipline. The latest edition contains new and significantly updated tables and is now available in eBook and online formats as well as the traditional print format. Print ISBN: 978-1-4822-0867-2 June 2014, 8-1/2 x 11, 2600 pp. Suggested Price: $169.95 / £108.00
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Dekker Encyclopedia of Nanoscience and Nanotechnology
Handbook of Microbiological Media
Third Edition, Seven Volume Set
Ronald M. Atlas
Fourth Edition
Sergey Edward Lyshevski Rochester Institute of Technology, New York, USA
With its original publication, the Dekker Encyclopedia of Nanoscience and Nanotechnology immediately became the reference against which all other nano references are measured. Continuing to cover the field as no other resource, the seven-volume Third Edition crosses disciplines to examine fundamental nano principles, theories, and methodologies, as well as the latest information on nano-relevant properties. It covers advances in nanoscale engineering, simulation tools, and computational methods. This extensively updated and revised edition also includes 50 new entries. Print ISBN: 978-1-4398-9134-6 December 2013, 8-1/2 x 11, 6779 pp. Suggested Price: $3400.00 / £2165.00
University of Louisville, Kentucky, USA
The fourth edition of a bestseller, this volume lists the formulation, method of preparation, and uses for over 4,000 microbiological media. With 30 percent more entries than the previous editions, the book includes recent information on international collection of microorganisms and expanded information on yeast, algae, and Archaea. The book also contains formulations and uses of media for isolation, culture, identification, and maintenance of microorganisms. The entries are arranged alphabetically by medium name and include synonyms, sources, trademarks, and more. Print ISBN: 978-1-4398-0406-3 eBook ISBN: 978-1-4398-0408-7 March 2010, 8-1/2 x 11, 2040 pp. Suggested Price: $231.00 / £147.00
Textbook
Fundamentals of Microfabrication and Nanotechnology
Textbook
Introduction to Computer Networks and Cybersecurity
Third Edition, Three-Volume Set
General References
Edited by
Chwan-Hwa (John) Wu and J. David Irwin Auburn University, Alabama, USA
Marc J. Madou University of California, Irvine, USA
Thoroughly revised and updated, this perennial bestseller lays the foundation for comprehensive theoretical and practical understanding of MEMS and NEMS. Expanded to three volumes to reflect substantial growth in the field, the first volume offers a rigorous theoretical treatment of micro- and nanosciences, and includes sections on solid-state physics, quantum mechanics, crystallography, and fluidics. The second volume presents a very large set of manufacturing techniques for micro- and nanofabrication and covers different forms of lithography, material removal processes, and additive technologies. The third volume focuses on manufacturing techniques and applications of Bio-MEMS and Bio-NEMS. Illustrated in color throughout, this seminal work also provides a cogent instructional text, supplying classroom and self-learners with worked-out examples and end-of-chapter problems. The author characterizes and defines major research areas and illustrates them with examples culled from the most recent literature and from his own work. Print ISBN: 978-0-8493-3180-0 August 2011, 8-1/2 x 11, 1992 pp. Suggested Price: $273.00 / £174.00
If a network is not secure, how valuable is it? A guide to computer networks and cybersecurity, this book highlights the interconnections between the two to demystify the complexities of designing secure modern networks. The book walks users through the fundamentals of networks, from an overview of Internet architecture through the protocol layers. It then delves into cybersecurity, covering both attack and defense techniques, and closes with a look at the emerging technologies that will alter the current state of multimedia communication and data center/cloud computing. Print ISBN: 978-1-4665-7213-3 eBook ISBN: 978-1-4665-7540-0 February 2013, 8-1/2 x 11, 1336 pp. Suggested Price: $129.95 / £49.99
89 Introduction to Quantum Biology
Getting Started with Business Analytics Insightful Decision-Making David Roi Hardoon Galit Shmueli Indian School of Business, Hyderabad
Helping you make sound decisions based on hard data, this self-contained guide provides an integrated framework of data mining in business analytics. It explores the contents, capabilities, and applications of business analytics without assuming any prior knowledge or technical skills. The authors describe business analytics from a non-commercial standpoint, demystify the main concepts and terminologies, and give many examples of real-world applications. They take you on a journey through this data-rich world, showing you how to deploy business analytics solutions in your organization.
Victor Anisimov James J.P. Stewart This book introduces the reader to the theory and methodology of quantum-mechanical modeling of chemical and biological systems. Given the immense complexity of such systems, there is a constant search for new methods. The goal of this text is to derive approximate (semi-empirical) methods to address this class of problems and to provide insight for their continued development. The authors cover such important topics as molecular dynamics, high performance computing, free energy calculations, statistical mechanics, long-range electrostatics, and manyelectron systems. They also discuss applications for water salvation, chemical reactions, conformational sampling, and structure relaxation. Print ISBN: 978-1-4398-3905-8 January 2014, 6-1/8 x 9-1/4, 432 pp. Suggested Price: $99.95 / £63.99
Print ISBN: 978-1-4398-9653-2 eBook ISBN: 978-1-4822-0587-9 March 2013, 7 x 10, 190 pp. Suggested Price: $59.95 / £38.99 For more information and a complete list of titles, visit us at www.crcpress.com
Introduction to Software for Chemical Engineers
Textbook
Edited by
From Molecular to Cellular Systems
Mariano Martín Martín
Edited by
Universidad de Salamanca, Spain
Michael E. Wall
General References
This book provides a quick reference guide to the use of different software packages for chemical engineering applications so that readers can become familiar with their capabilities. The book covers a range of software packages from Excel and general mathematical packages such as MATLAB® or Mathematica, to process simulators, CHEMCAD or ASPEN, equation-based modeling languages, gProms, EMSO, optimization software such as GAMS or specialized software like CFD or DEM codes that are applied to a number of representative examples from the design of chemical reactors, to cooling towers and chemical processes and operation. Each chapter covers a general introduction to the software, the basis behind the scenes as well as a few typical applications and examples.
Los Alamos National Laboratory, New Mexico, USA
Print ISBN: 978-1-4665-9936-9 June 2014, 6-1/8 x 9-1/4, 352 pp. Suggested Price: $89.95 / £57.99
Print ISBN: 978-1-4398-2722-2 eBook ISBN: 978-1-4665-7921-7 August 2012, 7 x 10, 392 pp. Suggested Price: $93.95 / £59.99
Laboratory Biosecurity Handbook
Textbook
Reynolds M. Salerno and Jennifer Gaudioso
An Introductory Textbook
Sandia National Laboratories, Albuquerque, New Mexico, USA
90
Quantitative Biology
Series: Chapman & Hall/CRC Mathematical & Computational Biology
Providing an overview of quantitative biology, this book presents practical tools for the observation, modeling, design, and manipulation of biological systems from the molecular to cellular levels. The book offers an introduction to fundamental concepts and computational, mathematical, and experimental studies of molecular and cellular behavior. The first section of the text covers basic, integrative concepts that form the foundation of the field. The next section reviews state-of-the-art methods in quantitative biology and case studies of specific systems. The last section focuses on important biological systems where modern quantitative methods are making an impact.
Understanding Nanomedicine Rob Burgess
In recognition of the vital need to protect legitimate facilities from the theft and misuse of dangerous pathogens and toxins, this text is a guide to the implementation of pathogen protection programs. The first sections of the book offer an historical overview of biological weapons activity, key principles of biosecurity and its integration into existing frameworks, and a discussion of biosecurity risk. Later sections discuss risk assessments, describe detailed components of a biosecurity program, and offer a graded approach to biosecurity through multiple risk levels. The book also covers risk prioritization of biological assets and biosecurity training.
Medical Nanotechnologies Incorporated, Richardson, Texas, USA
Print ISBN: 978-0-8493-6475-4 eBook ISBN: 978-1-4200-0620-9 June 2007, 6 x 9, 208 pp. Suggested Price: $129.95 / £84.00
Print ISBN: 978-981-4316-38-5 eBook ISBN: 978-1-4665-7050-4 June 2012, 6 x 9, 524 pp. Suggested Price: $149.95 / £95.00
Molecular Modeling at the Atomic Scale
What Every Engineer Should Know About Cyber Security and Digital Forensics
Methods and Applications in Quantitative Biology
This book comprehensively covers a broad range of therapeutic and diagnostic applications of nanotechnology, providing descriptions of cutting-edge discoveries along with historical perspectives. The text focuses on nanomaterials and nanoparticles, the sectors that hold the most promise for the future of medicine. The author looks at how nanotechnology can impact cancer treatment, clinical neuroscience, tissue engineering, drug delivery, and diagnostics. He also discusses the worldwide governmental regulatory impact on nanomedicine.
Joanna F. DeFranco The Pennsylvania State University, Malvern, USA
Edited by
Series: What Every Engineer Should Know
Ruhong Zhou IBM T.J. Watson Research Center, Yorktown Heights, New York, USA Series: Series in Computational Biophysics
Developments in molecular modeling from experimental and computational techniques have enabled a wide range of biological applications. This timely summary reflects the recent advances in bridging novel algorithms and high performance computing with characterization of important biological processes, such as folding dynamics of key proteins. It encompasses the perspectives of leading experts on this transformation in molecular biology, illustrating with state of the art examples how molecular modeling approaches are being applied to critical questions in modern quantitative biology. Print ISBN: 978-1-4665-6295-0 June 2014, 7 x 10, 350 pp. Suggested Price: $99.95 / £63.99
Designed for the non-security professional, this volume is an overview of cyber security and digital forensics. Topics include network and personal data security, the information security common body of knowledge, cloud and mobile computing, preparing for and responding to an incident, evidence handling, security compliance, and law. It also examines security certifications and reference manuals in the area of information security and digital forensics. By mastering the principles in this volume, engineering professionals will not only better understand how to mitigate the risk of security incidents and keep their data secure, but also understand how to break into this expanding field. Print ISBN: 978-1-4665-6452-7 November 2013, 6-1/8 x 9-1/4, 168 pp., Soft Cover Suggested Price: $59.95 / £38.99
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Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition.......................61
Adaptive Optics for Biological Imaging...................................26 Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery.............................................11 Advanced Biophotonics: Tissue Optical Sectioning.................27 Advanced Materials for Joint Implants....................................12 Advanced Practical Organic Chemistry, Third Edition...............3 Advanced Risk Analysis in Engineering Enterprise Systems......79 Advances in Chromatography, Volume 50..............................39 Advances in Chromatography, Volume 51..............................39 Advances in Chromatography, Volume 52..............................39 Advances in Natural Medicines, Nutraceuticals and Neurocognition......................................................................54 Advances in Therapeutic Engineering.....................................12 Age-Period-Cohort Analysis: New Models, Methods, and Empirical Applications......................................................79
Articular Cartilage...................................................................12 Artificial Human Sensors: Science and Applications.................27 Assistive Technology Assessment Handbook...........................13 Assistive Technology for Blindness and Low Vision..................13 Atomic Force Microscopy in Nanobiology..............................42 A-Z of Error-Free Research......................................................80
B
Basic Transport Phenomena in Biomedical Engineering, Third Edition...........................................................................13
Biopharmaceutical Supply Chains: Distribution, Regulatory, Systems and Structural Changes Ahead...............67
Batch Processing: Modeling and Design.................................63
Biophysics for Beginners: A Journey through the Cell Nucleus...........................................................................43
Bayesian Adaptive Methods for Clinical Trials..........................63
Bayesian Methods for Data Analysis, Third Edition..................81 Bayesian Methods in Epidemiology........................................72
Ambient Diagnostics..............................................................12
Bayesian Methods in Health Economics..................................72
Amino Acid Chelation in Human and Animal Nutrition............3
Bayesian Methods: A Social and Behavioral Sciences Approach, Third Edition...........................................81 Bayesian Phylogenetics: Methods, Computational Algorithms, and Applications..................................................70
An Introduction to Biomaterials, Second Edition.......................9
Benefit-Risk Assessment in Pharmaceutical Research and Development.........................................................................72
An Introduction to Generalized Linear Models, Third Edition...........................................................................85
Biochemical Sensors: Mimicking Gustatory and Olfactory Senses.....................................................................13
An Introduction to Physical Oncology: Towards Transitional Application of Multiscale Cancer Modeling..........78
Biodefense Research Methodology and Animal Models, Second Edition.......................................................................50
An Introduction to Systems Biology: Design Principles of Biological Circuits...................................................................78
Bioengineered Nanomaterials.................................................13
Analysis of Categorical Data with R.........................................79 Analysis of Complex Diseases: A Mathematical Perspective.............................................................................75
Biomedical Technology and Devices, Second Edition..............15
Basic Pharmacokinetics, Second Edition..................................68
Ambient Assisted Living..........................................................12
Analysis of Capture-Recapture Data........................................79
Biomedical Signal and Image Processing, Second Edition.......27
Bionanomaterials for Dental Applications.................................8
Bayesian Inference for Partially Identified Models: Exploring the Limits of Limited Data.......................................80
Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation, Second Edition..........................12
Biomedical Photonics Handbook, Second Edition: Therapeutic and Advanced Biophotonics................................15
Bionanotechnology................................................................42
Algorithms for Next-Generation Sequencing..........................75
Amyotrophic Lateral Sclerosis: Advances and Perspectives of Neuro-Nanomedicine.....................................54
Biomedical Photonics Handbook, Second Edition: Fundamentals, Devices, and Techniques.................................25
Biomimetics: Nature-Based Innovation...................................15
Bayesian Disease Mapping: Hierarchical Modeling in Spatial Epidemiology, Second Edition.................................72
Amino Acids: Biochemistry and Nutrition.................................3
Biomedical Engineering Fundamentals, Second Edition..........15
Bacterial NanoCellulose: A Sophisticated Multifunctional Material....................................................................................7
Age-Period-Cohort Models: Approaches and Analyses with Aggregate Data..............................................................79
Alzheimer’s Disease: Targets for New Clinical Diagnostic and Therapeutic Strategies ....................................................65
Biomedical Applications of Mesoporous Ceramics: Drug Delivery, Smart Materials and Bone Tissue Engineering..................................................................15
Biofluid Dynamics of Human Body Systems............................13 Biofluid Mechanics: The Human Circulation, Second Edition.......................................................................14
Biosensors and Environmental Health.......................................8 Biosensors Based on Nanomaterials and Nanodevices............43 Biosignal and Medical Image Processing, Third Edition...........27 Biosignal Processing: Principles and Practices..........................16 Biosimilars: Design and Analysis of Follow-on Biologics...........63 Biostatistics in Action: Basic and Advanced Statistical Modeling Using SPSS..............................................72 Biosurfactants: Research Trends and Applications...................34 Biotechnological Applications of Microalgae: Biodiesel and Value-Added Products.......................................35 Biotechnology in Agriculture and Food Processing: Opportunities and Challenges................................................35 Biotechnology in Medical Sciences.........................................35 Biotechnology of Fungal Genes..............................................35 Biotechnology of Plasma Proteins...........................................35 Bulbous Plants: Biotechnology................................................35
C Cadmium Telluride Quantum Dots: Advances and Applications.....................................................................43
Biofunctional Surface Engineering..........................................14
Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis.........................................................................36
Bioinformatics Database Systems............................................75
Cancer Causing Viruses and Their Inhibitors...........................53
Bioinformatics Ethics...............................................................70
Cancer Nanotechnology: Principles and Applications in Radiation Oncology................................................................43
Analysis of Mixed Data: Methods & Applications....................79
Biological and Bioenvironmental Heat and Mass Transfer.......14
Analysis of Variance for Functional Data..................................80
Biological and Medical Sensor Technologies...........................14
Carbohydrate Chemistry: Proven Synthetic Methods, Volume 2..................................................................................3
Analytical Chemistry for Technicians, Fourth Edition...............39
Biology of Oral Cancer: Key Apoptotic Regulators..................49
Carotenoids and Retinal Disease.............................................55
Applications of Microbial Engineering....................................34
Biomass Processing Technologies............................................34
Causal Inference.....................................................................63
Applications of Supramolecular Chemistry................................3
Biomaterials and Stem Cells in Regenerative Medicine..............7
Cellular In Vitro Testing: Methods and Protocols.....................43
Applied Categorical and Count Data Analysis.........................80
Biomaterials for Stem Cell Therapy: State of Art and Vision for the Future..........................................................7
Cellular Potts Models: Multiscale Extensions and Biological Applications............................................................77
Biomaterials Science: An Integrated Clinical and Engineering Approach..............................................................8
Chemical Components of Tobacco and Tobacco Smoke, Second Edition.......................................................................59
Biomaterials: Principles and Practices........................................7
Chemical Genomics and Proteomics, Second Edition...............3
Biomechanics of Artificial Organs and Prostheses....................14
Chemical Reagents for Protein Modification, Fourth Edition...........................................................................4
Applied Medical Image Processing: A Basic Course, Second Edition.......................................................................27 Applied Medical Statistics Using SAS.......................................71 Applied Meta-Analysis with R..................................................72 Applied Nonparametric Statistical Methods, Fourth Edition.........................................................................80 Applied Survey Data Analysis..................................................80
Biomechanics of Human Motion: Applications in the Martial Arts...................................................................15 Biomechanics: Principles and Practices...................................14
Title Index
A
Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds............................................68
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91
Chemistry of Heterocyclic Compounds.....................................4
Design and Analysis of Cross-Over Trials, Third Edition...........64
Chemistry of Natural Products: A Laboratory Handbook.........68
Design and Analysis of Experiments with R.............................81
Chemotherapy-Induced Neuropathic Pain..............................43
Design and Analysis of Experiments with SAS.........................81
Chitin and Chitosan Derivatives: Advances in Drug Discovery and Developments........................................65
Design and Analysis of Non-Inferiority Trials...........................64
Clinical and Statistical Considerations in Personalized Medicine............................................................64 Clinical Application of Computer-Guided Implant Surgery...................................................................................27 Clinical Nanomedicine Handbook..........................................44 CMOS Nanoelectronics: Innovative Devices, Architectures, and Applications...............................................36 CMOS: Front-End Electronics for Radiation Sensors................39 Coherent Raman Scattering Microscopy.................................28
Title Index
Comparative Anatomy and Phylogeny of Primate Muscles and Human Evolution...............................................88 Comprehensive Brachytherapy: Physical and Clinical Aspects.......................................................................28 Computational and Visualization Techniques for Structural Bioinformatics using Chimera.................................76 Computational Biomechanics of the Musculoskeletal System...................................................................................16 Computational Chemogenomics..............................................4 Computational Methods for Reproductive and Developmental Toxicology.....................................................59 Computational Model of Immune Response...........................76 Computational Neuroscience: Simulated Demyelinating Neuropathies and Neuronopathies.........................................55 Computational Systems Biology of Cancer.............................76 Computer Access for People with Disabilities: A Human Factors Approach....................................................16 Computer Systems Experiences of Users With and Without Disabilities: An Evaluation Guide for Professionals......................................................................16 Cone Beam Computed Tomography......................................28
92
Connective Tissue: Histophysiology, Biochemistry, Molecular Biology.....................................................................8 Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology.............50 Consumers and Nanotechnology: Deliberative Processes and Methodologies.................................................44
Design Controls for the Medical Device Industry, Second Edition.......................................................................16
Forensic DNA Analysis: Current Practices and Emerging Technologies..........................................................40 Forensic Toxicology: Mechanisms and Pathology...................60 Forensic Toxicology: Medico-Legal Case Studies.....................60 Foundational and Applied Statistics for Biologists Using R.......82 Freshwater Phytopharmaceutical Compounds........................69
Devices for Mobility and Manipulation for People with Reduced Abilities............................................................16
From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection.................................................17
Diagnostic Endoscopy............................................................17
From MEMS to Bio-MEMS and Bio-NEMS: Manufacturing Techniques and Applications..........................44
Dictionary of Antibiotics & Related Substances with CD-ROM, Second Edition.......................................................65
Functional Fold: Amyloid Structures in Nature........................54
Dynamic Documents with R and knitr....................................81
Fundamental QSARs for Metal Ions...........................................5
Dynamic Force Spectroscopy and Biomolecular Recognition............................................................................39
Fundamentals of Biofilm Research, Second Edition.................36
Dynamical Models in Medicine...............................................76
E EEG/ERP Analysis: Methods and Applications..........................55 Electroanalysis with Carbon Paste Electrodes..........................36
Fundamentals of Biomechanics..............................................17 Fundamentals of Microfabrication and Nanotechnology, Third Edition, Three-Volume Set.............................................89 Fungal Enzymes......................................................................62
G
Electrochemical Biosensors.....................................................44
Game-Theoretical Models in Biology......................................78
Electrokinetic Particle Transport in Micro-/Nanofluidics: Direct Numerical Simulation Analysis......................................44
Generalized Additive Models: An Introduction with R.............82
Emerging Imaging Technologies in Medicine.........................28 Encyclopaedia of Medical Physics...........................................17 Encyclopedia of Biopharmaceutical Statistics, Third Edition...........................................................................62 Encyclopedia of Biotechnology in Agriculture and Food (Print).....................................................................36 Endothelial Cell Plasticity in the Normal and Injured Central Nervous System.........................................................55 Engineering of Polysaccharide Materials: by PhosphorylaseCatalyzed Enzymatic Chain-Elongation.....................................8 Environmental Risk Assessment: A Toxicological Approach...............................................................................59
Generalized Estimating Equations, Second Edition..................83 Generalized Linear Models for Categorical and Continuous Limited Dependent Variables...............................83 Genetics, Genomics, and Breeding of Bananas.......................36 Genome Annotation...............................................................76 Getting Started with Business Analytics: Insightful Decision-Making ....................................................89
H Handbook of Analytical Validation..........................................65 Handbook of Applied Statistics in Pharmacology....................83 Handbook of Aqueous Solubility Data, Second Edition...........69
Epidemiology of Electromagnetic Fields..................................17
Handbook of Biofunctional Surfaces.......................................37
Epidemiology: Study Design and Data Analysis, Third Edition...........................................................................73
Handbook of Chemotherapeutic Engineering: Concepts, Feasibility, Safety, and Prospects — A Tribute to Shu Chien’s 80th Birthday...................................45
Essential Management Skills for Pharmacy and Business Managers...............................................................................67 Essential Statistics, Fourth Edition...........................................81
Handbook of Clinical Nanomedicine: From Bench to Bedside..............................................................................17 Handbook of Dynein..............................................................45
Correction Techniques in Emission Tomography.....................28
Event History Analysis with R..................................................82
Corrosion of Ceramic Materials, Third Edition...........................8
Every Molecule Tells a Story......................................................4
CRC Handbook of Chemistry and Physics, 95th Edition..........88
Exercises and Solutions in Statistical Theory............................82
Handbook of Harnessing Biomaterials in Nanomedicine: Preparation, Toxicity, and Applications.....................................9
CRC Handbook of Organic Photochemistry and Photobiology, Third Edition - Two Volume Set..........................4
Experiments in Pharmaceutical Chemistry, Second Edition.......................................................................69
Handbook of Imaging in Biological Mechanics.......................29
CRC World Dictionary of Medicinal and Poisonous Plants: Common Names, Scientific Names, Eponyms, Synonyms, and Etymology (5 Volume Set).............................59
Extending the Linear Model with R: Generalized Linear, Mixed Effects and Nonparametric Regression Models.............82
Critical Care Management for Laboratory Mice and Rats........51
D Data Mining for Bioinformatics...............................................70 Dekker Encyclopedia of Nanoscience and Nanotechnology....................................................................89 Dekker Encyclopedia of Nanoscience and Nanotechnology, Third Edition Seven Volume Set..............................................89 Design and Analysis of Bridging Studies.................................61
Extracellular Vesicles in Health and Diseases............................44
F Fermentation Microbiology and Biotechnology, Third Edition...........................................................................62 Flexible Imputation of Missing Data.......................................82 Flow Cyclometry: A Practical Guide........................................50 Fluctuation Theory of Solutions: Applications in Chemistry, Chemical Engineering, and Biophysics....................4 Fluorescent Protein Revolution...............................................28
Handbook of H+-ATPases........................................................55
Handbook of Intelligent Scaffold for Tissue Engineering and Regenerative Medicine...........................................................18 Handbook of Laboratory Animal Science, Volume III, Third Edition: Animal Models.................................................51 Handbook of Lipid Bilayers, Second Edition..............................5 Handbook of Markov Chain Monte Carlo...............................83 Handbook of Medical Device Regulatory Affairs in Asia ..........18 Handbook of Metallonutraceuticals........................................65 Handbook of Microbiological Media, Fourth Edition...............89 Handbook of Missing Data Methodology...............................83 Handbook of Oral Biomaterials.................................................9
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Handbook of Photomedicine..................................................29 Handbook of Safety Assessment of Nanomaterials: From Toxicological Testing to Personalized Medicine.......................45 Handbook of SAS® DATA Step Programming.........................76 Handbook of Spatial Statistics.................................................83 Handbook of Statistical Analyses using R, Third Edition...........84 Handbook of Statistical Analyses using SAS, Third Edition.......84
Introduction to BioMEMS.......................................................18 Introduction to Computer Networks and Cybersecurity.........89 Introduction to Ecological Sampling.......................................85
Linear Mixed Models: A Practical Guide Using Statistical Software.................................................................................85
Introduction to Experimental Biophysics: Biological Methods for Physical Scientists...............................................40
Linear Models with R..............................................................85
Introduction to Fluorescence..................................................40
Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application..........................................6
Introduction to GC-MS Coupling...........................................40
Logistic Regression Models.....................................................86
Introduction to Instrumentation in Life Sciences.....................40 Introduction to Lipidomics: From Bacteria to Man....................5
Handbook of Statistical Analyses Using Stata, Fourth Edition.........................................................................84
Introduction to Medical Imaging Management......................30
Handbook of Statistical Graphics Using SAS............................84
Introduction to Physics in Modern Medicine, Second Edition.......................................................................19
Handbook of Statistics in Clinical Oncology, Third Edition...........................................................................64 Handbook of Survival Analysis................................................73 Handbook of Therapeutic Biomarkers in Cancer.....................49 Handbook of Toxicology, Third Edition...................................60 Handbook of Vitamins, Fifth Edition..........................................5 Hansen Solubility Parameters: A User’s Handbook, Second Edition......................................................................................5 Heart Rate Variability (HRV) Signal Analysis: Clinical Applications...............................................................18 Hidden Markov Models for Time Series: An Introduction Using R.........................................................84 Horizons in Clinical Nanomedicine.........................................45 Hormesis in Health and Disease..............................................69 Human Eye Imaging and Modeling........................................29 Human Respiratory Viral Infections.........................................54 Humanoid Robotics and Neuroscience: Science, Engineering and Society.........................................................55 Hydrated Materials: Applications in Biomedicine and the Environment...........................................................................18 Hydroxyapatite Coatings for Biomedical Applications...............9
Introduction to Proteins: Structure, Function, and Motion..............................................................................5 Introduction to Quantum Biology..........................................89 Introduction to Software for Chemical Engineers....................90 Introduction to Statistical Data Analysis for the Life Sciences...........................................................................85
M Magnetic Resonance Imaging: The Basics...............................30 Making and Using Antibodies: A Practical Handbook, Second Edition.......................................................................66 Managing Your Biological Data with Python...........................71 Marine Biomaterials: Characterization, Isolation and Applications..............................................................................9 Marine Pharmacognosy: Trends and Applications...................69 Mass Spectrometry for the Novice..........................................41 Mass Transport of Nanocarriers..............................................45
Ion Mobility Spectrometry, Third Edition................................41
Measurement, Instrumentation, and Sensors Handbook, Second Edition (Two Volume Set): Spatial, Time, and Mechanical Measurement......................................................19
ISO 13485: A Complete Guide to Quality Management in the Medical Device Industry...........................9
Mechanics of Cellular Bone Remodeling: Coupled Thermal, Electrical, and Mechanical Field Effects...................................19
Itch: Mechanisms and Treatment............................................56
Mechanobiology of the Endothelium.....................................20
Introductory Mass Spectrometry, Second Edition...................41
J Joint Models for Longitudinal and Time-to-Event Data: With Applications in R............................................................73
K
Medical Applications of Artificial Intelligence..........................20 Medical Biostatistics, Third Edition..........................................73 Medical Device R&D Handbook, Second Edition....................10 Medical Devices and Systems, Second Edition........................20
Kidney: Toxicological Assessment...........................................60
Medical Equipment Management..........................................20
Knowledge-Driven Medicine: A Machine Learning Approach...............................................................................30
Medical Imaging: Principles and Practices..............................31
L Laboratory Animal Pocket Reference Series: 13- Volume Set.......................................................................52
I
Linear and Chiral Dichroism in the Electron Microscope.............................................................................41
Medical Imaging: Technology and Applications......................31 Medical Infrared Imaging: Principles and Practices.................31 Medical Robotics Handbook...................................................20 MEMS: Fundamental Technology and Applications................20
IACUC Handbook, Second Edition..........................................51
Laboratory Biosecurity Handbook...........................................90
Identifying Microbes by Mass Spectrometry Proteomics.........40
Laboratory Canine..................................................................52
Image Analysis and Modeling in Ophthalmology...................29
Laboratory Cat.......................................................................52
Methods in Brain Connectivity Inference through Multivariates Time Series Analysis...........................................56
Image Processing and Acquisition using Python.....................29
Laboratory Course in Tissue Engineering................................19
Methods of Statistical Model Estimation.................................86
Image Processing in Radiation Therapy...................................30
Laboratory Ferret....................................................................52
Image Processing: Tensor Transform and Discrete Tomography with MATLAB®......................................29
Laboratory Guinea Pig, Second Edition...................................52
Micro- and Nanobubbles: Fundamentals and Applications............................................................................21
Imaging for Plastic Surgery.....................................................30 Imaging in Cellular and Tissue Engineering............................30 Implementing Reproducible Research.....................................84 In Silico Bees...........................................................................71 Incomplete Categorical Data Design: Non-Randomized Response Techniques for Sensitive Questions in Surveys.........85 Infectious Diseases and Pathology of Reptiles: Color Atlas and Text...............................................................51 Inhalation Toxicology, Third Edition........................................60 Inside the Photon: A Journey towards Health..........................37 Interval-Censored Time-to-Event Data: Methods and Applications............................................................................73 Introduction to Biological Networks.......................................77
Laboratory Hamster and Gerbil...............................................52 Laboratory Manual in Biophotonics........................................19 Laboratory Mouse, Second Edition.........................................52 Laboratory Nonhuman Primate..............................................52 Laboratory Protocols in Applied Life Sciences.........................41 Laboratory Rabbit, Second Edition..........................................52 Laboratory Rat, Second Edition...............................................52 Laboratory Small Ruminant....................................................52 Laboratory Swine, Second Edition..........................................52 Labs on Chip: Principles, Design, and Technology..................37 LC-NMR: Expanding the Limits of Structure Elucidation.........41 Learning Bio-Micro-Nanotechnology......................................45
Title Index
Handbook of Personalized Medicine: Advances in Nanotechnology, Drug Delivery and Therapy.........................18
Metalloproteins: Structure, Functions, and Interactions..........31
Microarray Image and Data Analysis: Theory and Practice................................................................31 Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit.............................................................21 Microspheres and Microcapsules in Biotechnology: Design, Preparation and Applications.....................................37 Microsurgery: Advances, Simulations and Applications...........21 Mitochondrial Signaling in Health and Disease.........................6 Modeling and Control for Micro/Nano Devices and Systems...........................................................................78 Modelling Survival Data in Medical Research, Second Edition.......................................................................73 Molecular Engineering............................................................21 Molecular Modeling at the Atomic Scale: Methods and Applications in Quantitative Biology.......................................90
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93
Molecular Motors in Bionanotechnology................................46
Neuromorphic Olfaction........................................................57
Monte Carlo Calculations in Nuclear Medicine, Second Edition: Applications in Diagnostic Imaging...............31
Neurons and the DHA Principle..............................................57 Neuropeptides in Neuroprotection and Neuroregeneration...57
Pharmaceutical Industry Practices on Genotoxic Impurities...............................................................................66
MRI: Essentials for Innovative Technologies.............................32
Neuroscience of Handwriting: Applications for Forensic Document Examination..........................................................58
Pharmacogenomics of Alcohol and Drugs of Abuse................66
Multi-Detector CT Imaging Handbook, Two Volume Set.....................................................................32
Neurotechnology in National Security and Defense: Practical Considerations, Neuroethical Concerns..................................57
Multifunctional Molecular Materials........................................37
Neurotechnology: Premises, Potential, and Problems.............57
Multiobjective Optimization Methodology: A Jumping Gene Approach.....................................................71
Neuroviral Infections: General Principles and DNA Viruses......50
Monte Carlo Techniques in Radiation Therapy........................32
Neuroviral Infections: RNA Viruses and Retroviruses................50
Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Fourth Edition.............................70 Phenomics..............................................................................42 Physical Chemistry for Engineering and Applied Sciences.......22 Physics of Mammographic Imaging........................................33
Multiple Sclerosis Rehabilitation: From Impairment to Participation...........................................................................56
Neuroviral Infections: Two Volume Set...................................50
Physics of Thermal Therapy: Fundamentals and Clinical Applications............................................................................23
Multiporphyrin Arrays: Fundamentals and Applications..........46
Next Generation Sequencing: Platforms, Resources and Data Analysis...................................................................77
Physiology, Biophysics, and Biomedical Engineering...............23
Multivariate Statistical Methods: A Primer, Third Edition.........86
Pocket Handbook of Nonhuman Primate Clinical Medicine................................................................................53
Title Index
Multivariate Survival Analysis and Competing Risks................74
Non-Clinical Vascular Infusion Technology, Two Volume Set: Science and Techniques...............................51
Myocardial Tissue Engineering................................................21
Noninvasive Molecular Markers in Gynecologic Cancers........37
Polymer and Polymer-Hybrid Nanoparticles: From Synthesis to Biomedical Applications.............................10
Numerical Methods for Chemical Engineers Using Excel, VBA, and MATLAB...............................................22
Polymers for Vascular and Urogenital Applications..................10
N Nanoantenna: Plasmon-Enhanced Spectroscopies for Biotechnological Applications.................................................46 Nanobiomaterials: Development and Applications.................10 Nanobiotechnology Handbook..............................................46 NanoCellBiology: Multimodal Imaging in Biology & Medicine............................................................................46 Nanofabrication Handbook....................................................46 Nanomaterials for Electrochemical Sensing and Biosensing..............................................................................47
O Ocular Drug Delivery Systems: Barriers and Application of Nanoparticulate Systems....................................................66 OMICS Applications in Crop Science......................................38 Omics Technologies and Crop Improvement..........................38 OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences..........................................................38 Ophthalmology Imaging and Applications.............................32
Nanomedical Device and Systems Design: Challenges, Possibilities, Visions.................................................................10
Optical Imaging Techniques in Cell Biology, Second Edition.......................................................................32
Nanomedicine and Cancer Therapies.....................................47
Optical Nanoscopy and Novel Microscopy Techniques...........33
Nanomedicine and Drug Delivery..........................................47
Optical Techniques in Regenerative Medicine.........................10
Nanomedicine in Drug Delivery.............................................21
Optical, Acoustic, Magnetic, and Mechanical Sensor Technologies..........................................................................33
Nanomedicine: A Soft Matter Perspective...............................47
94
Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition..................................................69
Nanoparticles in Humans: Experiments, Methods and Strategies...............................................................................47
Optimal Design for Nonlinear Response Models.....................74 Organic Chemistry: A Mechanistic Approach............................6
Polytope Projects....................................................................71 Practical Guide and Spectral Atlas for Interpretive Near-Infrared Spectroscopy, Second Edition...........................42 Practical Guide to Human Research and Clinical Trials............62 Practical Guide to ICP-MS: A Tutorial for Beginners, Third Edition...........................................................................42 Practical Multivariate Analysis, Fifth Edition.............................86 Practical Statistics for Medical Research..................................74 Preventing Medical Device Recalls..........................................23 Principles and Applications of Therapeutic Ultrasound in Healthcare..............................................................................23 Principles of Neural Coding....................................................58 Probiotic Bacteria: Fundamentals, Therapy and Technological Aspects.............................................................62 Probiotics: Immunobiotics and Immunogenics.......................38 Process Validation in Manufacturing of Biopharmaceuticals, Third Edition...........................................................................63 Pulmonary Nanomedicine: Diagnostics, Imaging, and Therapeutics...........................................................................23
Nanoparticles: Drug Inhalation Therapy.................................47
Organic Chemistry: An Acid—Base Approach...........................6
Nanopatterning and Nanoscale Devices for Biological Applications............................................................................48
Orthopaedic Biomaterials in Research and Practice, Second Edition.......................................................................22
Nanoscience and Nanoengineering: Advances and Applications.....................................................48
Orthopaedic Biomechanics.....................................................22
Quality and Safety in Radiotherapy.........................................23
Ovarian Toxicology, Second Edition........................................61
Quality of Life Technology Handbook.....................................11
Nanostructures and Nanoconstructions based on DNA..........48 Nanostructures in Biological Systems: Theory and Applications.........................................................48 Nanotechnology and Human Health......................................48 Nanotechnology for the Delivery of Therapeutic Nucleic Acids..........................................................................22 Nanotechnology: The Whole Story.........................................48 Nanotoxicology: Progress toward Nanomedicine, Second Edition.......................................................................60 Natural Products Interactions on Genomes.............................61 Neuroadaptive Systems: Theory and Applications..................56 Neurobiological Basis of Suicide.............................................56 Neurobiology of Body Fluid Homeostasis: Transduction and Integration.................................................56
P Parkinson’s Disease, Second Edition........................................58 Patient-Focused Network Integration in BioPharma: Strategic Imperatives for the Years Ahead...............................67 Patient-Reported Outcomes: Measurement, Implementation and Interpretation..................................................................64 Patterns in Excitable Media: Genesis, Dynamics and Control............................................................................22 PCR Technology: Current Innovations, Third Edition................6 Phage Display In Biotechnology and Drug Discovery, Second Edition.......................................................................66 Pharmaceutical Accumulation in the Environment: Prevention, Control, Health Effects, and Economic Impact....................................................................................68
Q
Quality Operations Procedures for Pharmaceutical, API, and Biotechnology..........................................................62 Quantifying Morphology and Physiology of the Human Body Using MRI.........................................................33 Quantitative Biology: From Molecular to Cellular Systems......90 Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting...............................................64 Quantitative Graph Theory: Mathematical Foundations and Applications.....................................................................77 Quantitative Pharmacology: An Introduction to Integrative Pharmacokinetic-Pharmacodynamic Analysis..........................70 Quantitative Proteome Analysis: Methods and Applications............................................................................42 Quantitative Understanding of Biosystems: An Introduction to Biophysics...................................................6
Neurobiology of Chemical Communication...........................57
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V
Stem Cell Engineering: Principles and Practices......................24
Randomized Phase II Cancer Clinical Trials..............................65 Rational Basis for Clinical Translation in Stroke Therapy..........58 Rearing Animal and Plant Pathogen Vectors...........................53
Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix jacchus).......................53 Stochastic Dynamics for Systems Biology...............................78
Regenerative Engineering.......................................................11
Stochastic Modeling and Mathematical Statistics: A Text for Statisticians and Quantitative Scientists..................88
Regenerative Medicine, Stem Cells and the Liver....................63
Structural Glycobiology............................................................7
Regression Models as a Tool in Medical Research....................74
Supercritical Fluid Chromatography: Advances and Applications in Pharmaceutical Analysis..................................24
Rehabilitation Goal Setting: Theory, Practice and Evidence.....24 Reliable Design of Medical Devices, Third Edition...................24 Reproducible Research with R and RStudio.............................86
Survival Analysis in Medicine and Genetics.............................75
Responsible Nanobiotechnology: Philosophy and Ethics.........49 Richly Parameterized Linear Models: Additive, Time Series, and Spatial Models Using Random Effects...........86
Synthetic Gene Network: Modeling, Analysis and Robust Design Methods.........................................................78
RNA Nanotechnology.............................................................38
Systems Biology: Mathematical Modeling and Model Analysis.......................................................................25
RNA-seq Data Analysis: A Practical Approach..........................71 Robotic Surgery: Smart Materials, Robotic Structures, and Artificial Muscles..............................................................24 Robust Response Surfaces, Regression, and Positive Data Analyses.........................................................................87 Rodent Laparoscopy and Colonoscopy...................................53
S
Vibrational Spectroscopy for Tissue Analysis............................34 Viking DNA: The Wirral and West Lancashire Project...............54 Viral Diagnostics: Advances and Applications..........................39 Viral Hemorrhagic Fevers........................................................59 Vitamin-Binding Proteins: Functional Consequences...............54
Surface Imaging for Biomedical Applications..........................33
Suturing Principles and Techniques in Laboratory Animal Surgery: Manual and DVD......................................................53
RNA Nanotechnology and Therapeutics.................................49
Vascularization: Regenerative Medicine and Tissue Engineering..................................................................26
W Webb’s Physics of Medical Imaging, Second Edition...............26 What Every Engineer Should Know About Cyber Security and Digital Forensics.................................................90 Writing Dissertation and Grant Proposals: Epidemiology, Preventive Medicine and Biostatistics...............75
Szycher’s Handbook of Polyurethanes, Second Edition...........25
T Targeted Molecular Imaging...................................................34
Title Index
R
Targeted Muscle Reinnervation: A Neural Interface for Artificial Limbs...................................................................25 Terahertz Biomedical Science and Technology........................25 Textbook of Nanoneuroscience and Nanoneurosurgery.........58
Safety Pharmacology in Pharmaceutical Development: Approval and Post Marketing Surveillance, Second Edition.......................................................................70
Textbook of Organic Chemistry................................................7
SAS and R: Data Management, Statistical Analysis, and Graphics, Second Edition........................................................87
Theory of Factorial Design: Single- and Multi-Stratum Experiments...........................................................................88
Scaffolds for Tissue Engineering: Biological Design, Materials and Fabrication.......................................................24
Thin Layer Chromatography in Drug Analysis.........................68
Scalable Green Chemistry: Case Studies from the Pharmaceutical Industry.........................................................68 Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection, Third Edition................................61 Second Harmonic Generation Imaging...................................33
Theory of Drug Development.................................................66
Time Series Modeling of Neuroscience Data...........................88 Tissue and Organ Regeneration: Advances in Micro- and Nanotechnology....................................................................25 Tissue Engineering and Regenerative Medicine: A Nano Approach...................................................................26 Tissue Engineering: Principles and Practices............................26
Self-Assembled Peptide Nanostructures: Advances and Applications in Nanobiotechnology........................................49
Tomosynthesis Imaging..........................................................34
Skin Bioscience: A Molecular Approach..................................11
Topical Antimicrobials Testing and Evaluation, Second Edition.......................................................................67
Spike Timing: Mechanisms and Function................................58 Stated Preference Methods Using R........................................87 Statistical Analysis of Human Growth and Development.........74 Statistical Analysis of Questionnaires: A Unified Approach Based on R and Stata..............................................87 Statistical and Computational Methods in Brain Image Analysis...............................................................74 Statistical Computing with R..................................................87 Statistical Inference: An Integrated Approach, Second Edition.......................................................................87 Statistical Methods for Handling Incomplete Data..................88
Topical Nail Products and Ungual Drug Delivery....................67 Toxicologic Pathology: Nonclinical Safety Assessment............61 Transcranial Brain Stimulation.................................................59 Translational Medicine: The Future of Therapy?......................67 Transport Phenomena in Biomedical Engineering: Principles and Practices...........................................................26 Trends in Biophysics: From Cell Dynamics Toward Multicellular Growth Phenomena...........................................50
U
Statistical Methods for QTL Mapping.....................................77
Ultrasonic and Electromagnetic NDE for Structure and Material Characterization: Engineering and Biomedical Applications..........................................................11
Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition ................................................77
Understanding Biophotonics: Fundamentals, Advances and Applications.....................................................49
Statistics for Epidemiology......................................................75
Understanding Nanomedicine: An Introductory Textbook................................................................................90
Stem Cell Engineering Handbook...........................................38
Usability Testing of Medical Devices.......................................11
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95
A Abuhav; Itay.............................................................................9 Acharya; U. Rajendra..................................................12, 29, 32 Adams; Jesse...........................................................................48 Afifi; Abdelmonem.................................................................86 Agah; Arvin............................................................................20 Ahluwalia; Arti........................................................................43 Aho; Ken A.............................................................................82 Ai; Ye......................................................................................44 Aizaki; Hideo..........................................................................87 Akiyama; Tasuku.....................................................................56 Alemayehu; Demissie..............................................................64
Author Index
Allen; Matthew J.....................................................................52 Allman; A.R.............................................................................62 Alon; Uri.................................................................................78 Altman; Douglas G.................................................................74 Alvarez; Susana.......................................................................38 Alvir; Jose M...........................................................................64 Amantea; Diana......................................................................58 Amos; Linda A........................................................................45 Analoui; Mostafa....................................................................31 Anastasio; Mark A...................................................................28 Anisimov; Victor.....................................................................89 Aranda-Espinoza; Helim..........................................................20 Arjunan; Sridhar Poosapadi.....................................................16 Arus, Ph.D.; Emeric.................................................................15 Ashmead; H. DeWayne.............................................................3 Ashwell; Ken W. S...................................................................53 Asif; Erfan Syed.......................................................................62
96
Athanasiou; Kyriacos A...........................................................12 Atlas; Ronald M......................................................................89 Audette; Gerald F....................................................................17 Auletta; Carol.........................................................................60 Ayyachamy; M.......................................................................35 Azevedo; Vasco.......................................................................38
B Baccala; Luiz Antonio..............................................................56 Bacci; Silvia.............................................................................87 Backman; Vadim.....................................................................19 Bader; Augustinus.....................................................................7 Baio; Gianluca........................................................................72 Baltas; Dimos..........................................................................28 Baran; Szczepan.....................................................................53 Bar-Cohen; Yoseph.................................................................15 Barh; Debmalya..........................................................36, 37, 38 Barillot; Emmanuel.................................................................76 Barlow; Ann K.........................................................................25 Barnett; Adrian.......................................................................85
Bartolucci; Francesco..............................................................87
Cadenas; Enrique......................................................................6
Bastos-Filho; Teodiano Freire..................................................16
Cai; Yang................................................................................12
Bauer; Elizabeth......................................................................37
Caligiuri; Michael P.................................................................58
Bawa; Raj................................................................................17
Calzone; Laurence..................................................................76
Benaim; Michel......................................................................78
Campagnola; Paul J................................................................33
Benkeblia; Noureddine...........................................................38
Campbell; Elizabeth................................................................77
Bennett; B. Taylor...................................................................52
Campilho; Aurelio...................................................................29
Ben-Tal; Nir..............................................................................5
Cannistraro; Salvatore.............................................................39
Berard; Felipe M. ...................................................................52
Cappelleri; Joseph C...............................................................64
Berglund; Patricia A................................................................80
Carini; Claudio.......................................................................64
Berry; Scott M........................................................................63
Carlin; Bradley P................................................................63, 81
Best; Serena..............................................................................7
Carpi; Angelo.........................................................................36
Beyenal; Haluk........................................................................36
Carstens; Earl E.......................................................................56
Bilder; Christopher R...............................................................79
Castiglione; Filippo.................................................................76
Birkfellner; Wolfgang..............................................................27
Castillo; Jaime.........................................................................49
Bisen; Prakash Singh...................................................40, 41, 49
Cawthon; Andrew G...............................................................52
Bizzarri; Anna Rita...................................................................39
Celada; Franco.......................................................................76
Black; Jonathan.......................................................................22
Chader; Gerald J.....................................................................66
Blough; Eric R.........................................................................21
Chaloner; Penny.......................................................................6
Boehm; Frank.........................................................................10
Chan; Ivan S.F. .......................................................................64
Bogdanske; John J...................................................................53
Chan; T.M..............................................................................71
Bollen; Peter J. A.....................................................................52
Chandran; Krishnan B.............................................................14
Borkowski; Gary L...................................................................52
Chang; Huan-Tsung...............................................................17
Borsci; Simone........................................................................16
Chang; Jiang..........................................................................11
Botana; Luis M........................................................................61
Chang; Mark..........................................................................64
Bouchonnet; Stéphane...........................................................40
Chasan-Taber; Lisa .................................................................75
Brahmachari; Goutam............................................................68
Chattopadhyay; Subhagata....................................................12
Brayton; Cory.........................................................................52
Chen; Bor-Sen........................................................................78
Brenner; Sara..........................................................................44
Chen; Ding-Geng (Din)....................................................72, 73
Brey; Eric M............................................................................26
Chen; Ming-Hui.....................................................................70
Brock; Kristy K. ......................................................................30
Chen; Zehua..........................................................................77
Broemeling; Lyle D.................................................................72
Cheng; Ching-Shui.................................................................88
Bronzino; Joseph D........................ 7, 14, 15, 16, 21, 24, 26, 31
Cheng; Gordon......................................................................55
Brooks; Steve..........................................................................83
Cheng; Ji-Xin..........................................................................28
Broom; Mark..........................................................................78
Cheung; Yin Bun....................................................................74
Broström; Göran.....................................................................82
Chityala; Ravishankar..............................................................29
Bryce; C. F. A..........................................................................62
Cho; Art E...............................................................................31
Bundela; Saurabh...................................................................49
Cho; Sang Hyun.....................................................................43
Burg; Karen J.L. ......................................................................10
Chong; Stanford.....................................................................45
Burgess; Rob...........................................................................90
Choudhary; Vikas...................................................................20
Burgos; Alberto A...................................................................30
Chough; Keumhee Carrière....................................................79
Burkowski; Forbes J.................................................................76
Chow; Shein-Chung...................................................61, 62, 63
Bushmakin; Andrew G............................................................64
Chowriappa; Pradeep.............................................................70
Bustin; Stephen A.....................................................................6
Chung; Moo K.......................................................................74
Bux; Faizal..............................................................................35
Clark; Virginia A......................................................................86
Bycroft; Barrie W.....................................................................65
Clemons; Donna J..................................................................52
C Cabrini; Stefano......................................................................46
Codee; Jeroen...........................................................................3 Colilla; Montserrat..................................................................15
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Collaert; Nadine.....................................................................36
Donegan; John.......................................................................43
Freitas; Ana Cristina................................................................62
Collett; David.........................................................................73
Donnenberg; Albert D............................................................50
Friedman; Adam.....................................................................21
Constantinides; Christakis.......................................................30
Dormﾃ｡n; Gyﾃｶrgy......................................................................3
Fries; Richard C.......................................................................24
Cosnier; Serge........................................................................44
Douglas; Fred A......................................................................52
Frokjaer; Sven.........................................................................69
Cotton; Simon Anthony...........................................................4
Drﾄトhici; Sorin........................................................................77
Fuentes; Montserrat................................................................83
Courtney; Angela...................................................................53
Drobne; Damjana...................................................................48
Fukuda; Toshio.......................................................................21
Cox; Guy................................................................................32
Dua; Sumeet..........................................................................70
Fung; Glenn...........................................................................30
Craig; Fiona Elizabeth.............................................................50
Dunscombe; Peter..................................................................23
Cristini; Vittorio......................................................................78
DuRaine; Grayson D...............................................................12
Crowder; Martin J...................................................................74
Dwivedi; Yogesh.....................................................................56
D
E
Gabrielsson; Johan..................................................................70 Gabrielsson; Johan..................................................................70 Gad; Shayne C.......................................................................70
Ebadi; Manuchair ..................................................................58
Galecki; Andrzej T...................................................................85
Dakshinamurti; Krishnamurti..................................................54
Eckelman; William C...............................................................34
Gama; Miguel..........................................................................7
Dakshinamurti; Shyamala.......................................................54
Eiceman; G.A..........................................................................41
Gamerman; Dani....................................................................87
Dancey; Janet E......................................................................49
Ekstrom; Claus Thorn.............................................................85
Gandrud; Christopher............................................................86
Danneman; Peggy J................................................................52
Elias; Dirk Christian.................................................................12
Garcﾃｭa; Miguel Manzano........................................................15
Darling; Eric M.......................................................................12
Elias; Eldho.............................................................................47
Garcia; Nuno M......................................................................12
Darvas; Ferenc..........................................................................3
Elman; Noel..............................................................................8
Gardiner; Chris.......................................................................44
Das; Rabindra Nath................................................................87
El-Mansi; E. M. T.....................................................................62
Garvey; Paul R........................................................................79
Dasgupta; Amitava.................................................................66
Emmert-Streib; Frank..............................................................77
Gatenholm; Paul.......................................................................7
Datta; Ashim K.......................................................................14
Emond; Claude.......................................................................48
Gaudioso; Jennifer..................................................................90
Davidson; Michael W..............................................................28
Enache; Monica........................................................................5
Gehr; Peter.............................................................................47
Dawood; Mohammad............................................................28
Eren; Halit...............................................................................19
Gelfand; Alan E.......................................................................83
Day; Richard N.......................................................................28
Evans; William Howard...........................................................50
Gelman; Andrew....................................................................83
De Bartolo; Loredana................................................................7
Everitt; Brian S..................................................................71, 84
Genin; Guy.............................................................................29
de la Chapelle; Marc Lamy.....................................................46 de Leon; Alexander R..............................................................79 De Luca Jr.; Laurival Antonio...................................................56 De Silva; Titus.........................................................................67 Dean; Dorothy E.....................................................................60 DeFranco; Joanna F.................................................................90 Dehmer; Matthias..................................................................77 Demain; Arnold L...................................................................62 Der; Geoff..............................................................................71 Der; Geoff..............................................................................84 Der; Geoff..............................................................................84 Derelanko; Michael J...............................................................60 Devillers; James.......................................................................71 Diakides; Mary........................................................................31 Diamantopoulos; Panagiotis...................................................27 Dias; Miguel Sales...................................................................12 Dickson; Charles.....................................................................69 Diggle; Peter..........................................................................83 DiLorenzo; Patricia M.............................................................58 Diogo; Rui..............................................................................88 Diwekar; Urmila......................................................................63 Dobson; Annette J..................................................................85 Dogramadzi; Sanja.................................................................20
F Fadeel; Bengt.........................................................................45 Fafrowicz; Magdalena.............................................................56 Fan; Yubo...............................................................................16 Faraway; Julian J.....................................................................82 Faraway; Julian J.....................................................................85 Farncombe; Troy....................................................................31 Federici; Stefano...............................................................13, 16 Fedorov; Valerii V....................................................................74 Felli; James..............................................................................72 Field; Garrett..........................................................................52 Field; Karl J.............................................................................52 Finlayson; Marcia....................................................................56 Firman; Keith..........................................................................46 Fisher; John P..........................................................................26 Fisher; Robert J.......................................................................26 Fitzmaurice; Garrett................................................................83 Fleming; Tony ........................................................................37 Flower; M A............................................................................26 Folch; Albert...........................................................................18 Fortman; Jeffery D..................................................................52 Foulkes; Frank R......................................................................22 Fournier; Ronald L..................................................................13
Author Index
Crowley; John.........................................................................64
G
Geyer; Clarence Ronald..........................................................66 Gheshmi; Siavash...................................................................24 Ghetti; Francesco......................................................................4 Gill; Jeff...................................................................................81 Giordano; James ....................................................................57 Glick; Stephen........................................................................34 Gnaldi; Michela......................................................................87 Goddard III; William A............................................................31 Goldstein; Walter E.................................................................68 Gonnella; Nina C....................................................................41 Good; Phillip I.........................................................................80 Gopinath; Chirukandath.........................................................61 Gordon; Paul M.K...................................................................76 Goyal; Megh R.................................................................13, 14 Greaves; John.........................................................................41 Green; Owen P.......................................................................51 Gregory III; Jesse F.....................................................................5 Griesbeck; Axel.........................................................................4 Grigoryan; Artyom M.............................................................29 Grigoryan; Merughan M........................................................29 Grinberg; Nelu.......................................................................39 Grunwald; Armin ...................................................................49 Grushka; Eli............................................................................39
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97
Gunduz; Mehmet...................................................................36
Hoering; Antje........................................................................64
Kalcher; Kurt...........................................................................36
Guo; Peixuan..........................................................................49
Hollinger; Jeffrey O...................................................................9
Kamath; Markad V..................................................................18
Gupta; Satya Prakash..............................................................53
Holmgren; Eric B....................................................................66
Kamel; Nidal...........................................................................55
Gupta; V. K.............................................................................35
Hoover; Dallas G.....................................................................36
Kane; Suzanne Amador..........................................................19
Gupta; Vijai Kumar.................................................................34
Horton; Nicholas. J.................................................................87
Kaneko; Yoshiro........................................................................8
Gustafson; Paul.......................................................................80
Hoskin; Peter J........................................................................28
Karagkiozaki; Varvara..............................................................45
Gutierrez-Galvez; Agustin.......................................................57
Hothorn; Torsten....................................................................84
Karpas; Z................................................................................41
Guttman; András......................................................................3
Hovgaard; Lars.......................................................................69
Karwowski; Waldemar............................................................56
Guttorp; Peter........................................................................83
Howard; Gary C.....................................................................66
Kaser; Matthew R...................................................................66
Hoyer; Patricia B.....................................................................61
Kasugai; Yu.............................................................................54
Hsiao; Chin-Fu........................................................................61
Kateb; Babak..........................................................................58
Hu; Jerry C..............................................................................12
Katsaras; John...........................................................................6
Huang; Ying-Ying...................................................................29
Katz; Sidney A........................................................................60
Hubbard-Van Stelle; Scott.......................................................53
Kawata; Satoshi......................................................................46
Hupe; Philippe........................................................................76
Kelkar; Ajit D...........................................................................48
Huston; Ronald L....................................................................17
Kendler; Jonathan...................................................................11
H Haghi; A. K.............................................................................47 Haider; Syed Imtiaz................................................................62
Author Index
Hamblin; Michael R................................................................29 Hancock; John M....................................................................42 Handfield; Robert...................................................................67 Hani; Ahmad Fadzil Mohamad...............................................33 Hankenson; F. Claire...............................................................51 Hansen; Axel K.......................................................................52
Iannone; Eugenio...................................................................37
Hansen; Charles M...................................................................5
Ibrahim; Joseph G...................................................................73
Haque; Farzin.........................................................................49
Iglic; Aleš................................................................................48
Hardin; James W.....................................................................83
Imae; Toyoko..........................................................................11
Harding; Stephen E................................................................54
Imai; Kazuhiro........................................................................42
Hardisty; Jerry F.......................................................................61
Indrayan; Abhaya...................................................................73
Hardman; Craig D..................................................................53
Iniewski; Kris...........................................................................31
Hardoon; David Roi................................................................89
Iniewski; Krzysztof......................................... 14, 20, 21, 33, 48
Harrison; Paul.........................................................................44
Iordache; Octavian.................................................................71
Hau; Jann...............................................................................51
Irwin; J. David.........................................................................89
Hay; David C..........................................................................63
Ison; Keith..............................................................................20
Haycock; John........................................................................43
98
I
Haynes; William M..................................................................88 He; Hua..................................................................................80 He; Yan...................................................................................69 Healing; Guy..........................................................................51 Hedaya; Mohsen A.................................................................68 Heeringa; Steven G.................................................................80 Heiss; John D..........................................................................58 Heldman; Dennis R.................................................................36 Herbert; Katherine G..............................................................75 Hernan; Miguel A...................................................................63 Herr; Daniel J.C.......................................................................48 Herrera; Esperanza Meléndez..................................................55 Hewett; Terry A......................................................................52 Hilbe; Joseph M......................................................................83 Hilbe; Joseph M......................................................................86 Hill, Jr.; Herbert H...................................................................41 Hirose; Keiko..........................................................................45
J
Kenward; Michael G.........................................................64, 83 Kessel; Amit..............................................................................5 Khademhosseini; Ali...............................................................25 Khan; Firdos Alam..................................................................35 Khan; Yusuf............................................................................11 Khan; Zakir.............................................................................49 Khang; Gilson.........................................................................18 Kilkenny; Dawn......................................................................19 Kim; Dongho..........................................................................46 Kim; Jae Kwang......................................................................88 Kim; Sang Geon.....................................................................60 Kim; Se-Kwon...............................................................9, 65, 69 King; Michael A......................................................................31
Jackson; Todd A......................................................................52 Jacobson; Elliott......................................................................51 Jacoby; Edgar...........................................................................4 Jain; Parijat.............................................................................69 Jameson; David M..................................................................40 Jarvis; Suzi..............................................................................54 Jena; Bhanu P..........................................................................46 Jewell; Nicholas P....................................................................75 Jiang; Qi.................................................................................64 Jiang; Xiaoyi...........................................................................28 Jobling; Mark..........................................................................54 Johnson; Alan Kim..................................................................56 Jones; Byron ..........................................................................64 Jones; Galin............................................................................83 Jung; Sin-Ho...........................................................................65 Jurczyk; Mieczyslaw..................................................................8
K
Hjorth; Stephan......................................................................70 Hodges; James S.....................................................................86
Kenkel; John...........................................................................39
Kadokawa; Jun-ichi...................................................................8
King; Turi................................................................................54 Kitazawa; Haruki.....................................................................38 Klein; John P...........................................................................73 Kleinman; Ken........................................................................87 Klemm; Dieter..........................................................................7 Knoll; Wolfgang......................................................................37 Kobayashi; Katsumi................................................................83 Koenig; Stefan........................................................................68 Kole; Chittaranjan...................................................................36 Kolev; Bozhidar Dimitrov........................................................55 Komsta; Lukasz.......................................................................68 Korpelainen; Eija.....................................................................71 Kraikivski; Pavel.......................................................................50 Kralj-Iglic; Veronika.................................................................48 Kremling; Andreas..................................................................25 Krishnan; Sunil........................................................................43 Krishnaswamy; N R.................................................................68 Krull; Ira S...............................................................................65
Kaiyu; Raymond Tong............................................................18
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Kuang; Yang...........................................................................76
Lobel; Leslie............................................................................39
McCrea; Rachel S...................................................................79
Kubby; Joel A..........................................................................26
Logothetidis; Stergios.............................................................45
McDowall; Jennifer S..............................................................77
Kucerka; Norbert......................................................................6
Lokhande; Jayant N................................................................65
Meigooni; Ali S.......................................................................28
Kucklick; Theodore R..............................................................10
Loughin; Thomas M...............................................................79
Mele; Maria Laura...................................................................16
Kuiken; Todd A.......................................................................25
Louis; Thomas A.....................................................................81
Mendelson; Mel I...................................................................45
Kumar Parashar; Rakesh............................................................4
Louzada-Neto; Francisco........................................................87
Meng; Xiao-Li.........................................................................83
Kumar; Arun...........................................................................21
Lovald; Scott..........................................................................22
Menon; Sandeep M................................................................64
Kumar; Dinesh........................................................................16
Lundblad; Roger L....................................................................4
Merillon; Jean-Michel..............................................................35
Kundu; Tribikram....................................................................11
Lundblad; Roger L..................................................................35
Merkle; Edgar C......................................................................83
Kuo; Lynn...............................................................................70
Lygo; Barry...............................................................................3
Micieli; Giuseppe....................................................................58
Kupper; Lawrence L................................................................82
Lyshevski; Sergey Edward.......................................................89
Micou; Melissa Kurtis..............................................................19
Kurosu; Masaaki.....................................................................16 Kwak; Brenda R......................................................................50
L
M Ma; Guanghui........................................................................37 Ma; Shuangge........................................................................75 MacDonald; Iain L..................................................................84
Migliaresi; Claudio..................................................................24 Migon; Helio S.......................................................................87 Mikos; Antonios G..................................................................26 Milano; Franco.......................................................................17 Milne; Christopher-Paul .........................................................67
La Riviere; Patrick....................................................................28
Machtoub; Lina......................................................................54
Lagally; Eric............................................................................21
Madou; Marc J............................................................44, 89, 90
Lai-Kwan; Chau......................................................................17
Mahmood; Farida...................................................................53
Land; Kenneth C....................................................................79
Maibach; Howard I.................................................................67
Landrum; John T.....................................................................55
Maitland; Duncan J.................................................................15
Langford; Richard...................................................................43
Maki; Minna...........................................................................34
Langman; Loralie J. ................................................................66
Malik; Aamir Saeed.................................................................55
Laurencin; Cato T...................................................................11
Malsch; Ineke.........................................................................48
Law; Victor J...........................................................................22
Man; K.F.................................................................................71
Lawson; Andrew B..................................................................72
Manduchi; Roberto................................................................13
Lawson; John..........................................................................81
Manly; Bryan F.J................................................................85, 86
Le Bourg; Eric.........................................................................69
Mansour; Heidi M...................................................................21
Lee; Heewon..........................................................................66
Maramorosch; Karl.................................................................53
Lee; J. Jack..............................................................................63
Marco; Santiago.....................................................................57
Leisch; Friedrich......................................................................84
Marek; Tadeusz.......................................................................56
Leonard; John...........................................................................3
Markey; Mia K........................................................................33
Leonov; Sergei L. ...................................................................74
Marks; Robert S......................................................................39
Leray; Claude...........................................................................5
Marr; Rena.............................................................................52
Levack; William.......................................................................24
Marsh; Derek............................................................................5
Lewandowski; Zbigniew.........................................................36
Martin; Brent J........................................................................52
Lewis; Cornelius......................................................................17
MartĂn; Mariano MartĂn..........................................................90
Lewis; Paul O..........................................................................70
Marwaha; Satwinder S............................................................35
Li Fong Yau; Sam....................................................................42
Matcher; Stephen J.................................................................10
Li; Arthur................................................................................76
Matchett; C. Andrew..............................................................52
Li; Guangyong........................................................................78
Matinlinna; Jukka Pekka............................................................9
Nadeau; Jay............................................................................40
Li; Jialiang...............................................................................75
Matson; Robert S....................................................................61
Nagy; John.............................................................................76
Li; Jun.....................................................................................43
Matsuura; Katsuhisa................................................................21
Naidu; M. U. R.......................................................................62
Li; Wan-Ju...............................................................................26
Matteoli; Enrico........................................................................4
Najarian; Kayvan....................................................................27
Liang; Hualou.........................................................................16
Mattison; Donald R.................................................................59
Nakamura; Suguru.................................................................55
Lim; Teik-Cheng.....................................................................12
May; Susanne.........................................................................86
Nakanishi; Yoshitaka...............................................................18
Liu; Jen-pei.............................................................................61
Mazutti; Marcio Antonio.........................................................34
Nakatani; Tomoaki..................................................................87
Liu; Ray H...............................................................................40
Mazza; Christian.....................................................................78
Navarro Alberto; Jorge A.........................................................85
Ljungberg; Michael................................................................31
McCauley; Ronald A.................................................................8
Neelon; Brian. H.....................................................................82
Miniussi; Carlo........................................................................59 Mironov; Sergey Pavlovich.......................................................8
Author Index
Kurniawan; Sri........................................................................13
Mishra; Munmaya....................................................................8 Mittra; James..........................................................................67 Mohammed; Linton A............................................................58 Molenberghs; Geert...............................................................83 Monteiro-Riviere; Nancy A......................................................60 Moore Jr; James E...................................................................15 Morgan; Byron J. T.................................................................79 Morgan; Stephen P.................................................................10 Moros; Eduardo .....................................................................23 Mostaert; Anika......................................................................54 Motta; Antonella....................................................................24 Movasaghi; Zanyar.................................................................34 Mucignat-Caretta; Carla.........................................................57 Mudhoo; Ackmez...................................................................34 Muftuler; L. Tugan..................................................................33 Muller; Peter...........................................................................63 Mulligan; Catherine N............................................................34 Mundt; Arno J........................................................................23 Murthy; S Narasimha..............................................................67 Murthy; Sreekant....................................................................51
N
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99
Neu; Corey.............................................................................29
Peterson; Donald R.................. 7, 14, 15, 16, 20, 21, 24, 26, 31
Reddi; A. Hari.........................................................................12
Newman; Michael C.................................................................5
Pezzotti; Giuseppe..................................................................12
Rees; D.G...............................................................................81
Ng; E. Y. K. ......................................................................29, 32
Pfeiffer; Ronald F.....................................................................58
Rehman; Ihtesham ur.............................................................34
Nieh; Mu-Ping..........................................................................6
Phillips-Farfán; Bryan V...........................................................55
Rehman; Shazza.....................................................................34
Ninan; Neethu.......................................................................47
Pillai; C. N................................................................................7
Reiser; Ingrid..........................................................................34
Noel; Rebecca........................................................................72
Pillai; K. Sadasivan..................................................................83
Ribuffo; Diego........................................................................30
Nolan; John............................................................................55
Pillay; Michael........................................................................36
Ripamonti; Ugo......................................................................26
Nolan; Tania.............................................................................6
Pinto; Cesar Ariel....................................................................79
Rittgers; Stanley E...................................................................14
Nordlund; Thomas M...............................................................6
Pispas; Asterios.......................................................................10
Rivetti; Angelo........................................................................39
Northrop; Robert B.................................................................12
Placidi; Giuseppe....................................................................32
Rizopoulos; Dimitris ...............................................................73
Nyberg; Fred..........................................................................57
Polizeli; Maria de Lourdes T. M...............................................62
Rizzo; Maria L.........................................................................87
Popp; James A........................................................................61
Robins; James M.....................................................................63
Porreca; Frank.........................................................................43
Robinson; Andrew P................................................................86
Powers; Robert H....................................................................60
Roboz; John............................................................................41
Preedy; Victor R........................................................................8
Rodgman; Alan.......................................................................59
Preziosi; Luigi..........................................................................77
Rodrigues; Joel Jose P.C...........................................................12
Procter; Garry...........................................................................3
Rogers; Ben............................................................................48
Pucci; Annemarie....................................................................46
Rompas; Jenny .......................................................................45
Pudipeddi; Sridevi...................................................................29
Roosli; Martin.........................................................................17
Pumera; Martin......................................................................47
Rosales; Romer.......................................................................30
O
Author Index
O’ Connell; John P....................................................................4 O’Brien; Robert M..................................................................79 O’Brien; Sean M.....................................................................82 Oelgemöller; Michael...............................................................4 Olsen Alstrup; Aage K.............................................................52 Omelyanenko; Nikolay Petrovich..............................................8 Ong; Kevin L..........................................................................22 Orrenius; Sten..........................................................................6 Ospina; Gabriel Gutiérrez ......................................................55 Ouahab; Lahcene...................................................................37
Qian; Shizhi............................................................................44
Oviedo-Orta; Ernesto..............................................................50
Qin; Qing-Hua........................................................................19
Ozaki; Tohru...........................................................................88
Quattrocchi; Umberto............................................................59
P Pabst; Georg............................................................................6
100
Q
Quiroga; Rodrigo Quian.........................................................58
R
Rose; Felicity R........................................................................10 Rosen; Yitzhak..........................................................................8 Rossini; Paolo M.....................................................................59 Rother; Kristian.......................................................................71 Rothmann; Mark D. ...............................................................64 Rozen; Warren........................................................................30 Rubenzer; Bernard..................................................................30
Packer; Lester...........................................................................6
Rabe-Hesketh; Sophia.............................................................84
Pan; Dipanjan.........................................................................47
Raffa; Robert B........................................................................43
Panesar; Parmjit S...................................................................35
Raheja; Dev............................................................................23
Panzeri; Stefano......................................................................58
Rahim; Nur Aida Abdul...........................................................30
Papaefthymiou; Georgia C.....................................................10
Rai; Mahendra........................................................................62
Parashis; Andreas....................................................................27
Rajan; Rajabalaya....................................................................69
Patel; Vinood............................................................................8
Rakovich; Yury........................................................................43
Pathak; Yashwant Vishnupant.................................................65
Ramakrishna; Seeram...............................................................7
Paulson; Daryl S......................................................................67
Ramalingam; Murugan.......................................................7, 26
Paulus; Walter.........................................................................59
Ramawat; Kishan Gopal..........................................................35
Pavone; Francesco S...............................................................33
Ramesh; Santhanam...............................................................69
Pawlicki; Todd .......................................................................23
Ramsland; Paul A......................................................................7
Payne; David J........................................................................65
Rangayyan; Rangaraj M..........................................................32
Peace; Karl E.....................................................................72, 73
Rangelov; Stanislav.................................................................10
Peattie; Robert A.....................................................................26
Rani; P. Usha...........................................................................62
Peer; Dan...........................................................................9, 22
Rankin Riley; Margaret............................................................53
Peng; Roger D........................................................................84
Rao; Kalipatnapu N.................................................................60
Pennathur; Sumita..................................................................48
Rao; R. Bharat.........................................................................30
Perfetti; Thomas A..................................................................59
Rathore; Anurag S..................................................................63
Pergolizzi, Jr.; Joseph V............................................................43
Rattan; Suresh I. S...................................................................69
Perret-Gentil; Marcel..............................................................53
Raval; Alpan............................................................................77
Persaud; Krishna C..................................................................57
Ray; Animesh..........................................................................77
Rubinstein; Israel....................................................................17 Rudolph; Alan S......................................................................65 Rueda; Luis.............................................................................31 Ruzek; Daniel ...................................................................50, 59 Ruzer; Lev S............................................................................47 Ryan; James G........................................................................48 Rychtar; Jan............................................................................78
S Saba; Luca........................................................................30, 32 Sahota; Pritam S.....................................................................61 Salem; Harry...........................................................................60 Salerno; Reynolds M...............................................................90 Sall; Amadou..........................................................................39 Salyanov; V.I...........................................................................48 Samaniego; Francisco J...........................................................88 Sameshima; Koichi.................................................................56 Santhanam; Ramasamy..........................................................69 Sargent; Ian L.........................................................................44 Sashegyi; Andreas...................................................................72 Sasso; Luigi.............................................................................49 Sato; Kazuo............................................................................87
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Sinha; Sitabhra.......................................................................22
Tang; K.S................................................................................71
Si-shen; Feng..........................................................................45
Tang; Man-Lai .......................................................................85
Schaffer; David.......................................................................24
Skuridin; S.G...........................................................................48
Tang; Wan..............................................................................80
Schapiro; Steven J...................................................................51
Skuse; Gary............................................................................70
Teixeira; Marie B.....................................................................16
Schattschneider; Peter............................................................41
Slutsky; Leonid Ilyich................................................................8
Tercero; Carlos........................................................................21
Scheike; Thomas H.................................................................73
Smeeton; Nigel C...................................................................80
Thassu; Deepak .....................................................................66
Scherer; Marcia......................................................................13
Smith; Michael B......................................................................6
Thomas; Robert......................................................................42
Schiessel; Helmut....................................................................43
Smith; Paul E............................................................................4
Throne-Holst; Harald..............................................................44
Schiffman; Beth M..................................................................53
Smithson; Michael..................................................................83
Tian; Guo-Liang......................................................................85
Schmoll; Monika.....................................................................34
Sofer; Gail...............................................................................63
Tiwari; Ashutosh.....................................................................13
Schmorrow; Dylan..................................................................56
Soh; Jung...............................................................................76
Tiwari; Atul.............................................................................13
Schneider; Hans-Jörg................................................................3
Somasundaram; Siva..............................................................61
Toko; Kiyoshi..........................................................................13
Scholey; Andrew.....................................................................54
Somervuo; Panu.....................................................................71
Tramontano; Anna..................................................................71
Scholl; Gerd............................................................................44
Son; Joo-Hiuk.........................................................................25
Tran; C. Lang..........................................................................60
Scholz; Martin........................................................................14
Sørensen; Helle.......................................................................85
Tsia; Kevin..............................................................................49
Schroeder; Valerie...................................................................52
Soto; Eivind............................................................................44
Tsiatis; Anastasios ...................................................................83
Schultz Feuser; Aimee E..........................................................25
Splinter; Robert......................................................................27
Tsuda; Akira............................................................................47
Schulz; Richard.......................................................................11
Sprawls; Perry.........................................................................17
Tsuge; Hideki..........................................................................21
Scianna; Marco.......................................................................77
Sprent; Peter..........................................................................80
Tu; Xin M...............................................................................80
Sebastian; Mathew.................................................................47
Sridhar; S................................................................................22
Tuchin; Valery V......................................................................27
Seco; Joao..............................................................................32
Stephanova; Diana Ivanova....................................................55
Tuimala; Jarno.........................................................................71
Seeman; Jennifer L..................................................................52
Stewart; James J.P...................................................................89
Tuohy; Maria..........................................................................34
Selimovic; Seila.......................................................................48
Stodden; Victoria....................................................................84
Semmlow; John L...................................................................27
Stough; Con Kerry Kenneth....................................................54
Sensen; Christoph W..............................................................76
Stover; Patrick J.........................................................................5
Serda; Rita Elena.....................................................................45
Strand; Sven-Erik..............................................................17, 31
Shahinpoor; Mohsen..............................................................24
Strandbakken; Pal...................................................................44
Shalaby; Shalaby W................................................................10
Strezov; Vladimir....................................................................34
Shalaby; Waleed ....................................................................10
Strochlic; Allison Y...................................................................11
Shao; Jun................................................................................88
Su; Zhi-Guo............................................................................37
Sharma; Anjana......................................................................40
Suckow; Mark A...............................................................51, 52
Sharma; Sanjay K....................................................................34
Sun; Jianguo...........................................................................73
Sharon; Maheshwar................................................................42
Sung; Wing-Kin......................................................................75
Sharp; Patrick.........................................................................52
Suri; Jasjit S.......................................................................29, 32
Shaw; Chris C.........................................................................28
Suttie; John W...........................................................................5
Sherma; Joseph......................................................................68
Svancara; Ivan........................................................................36
Shewale; Jaiprakash G.............................................................40
Svendsen; Winnie Edith..........................................................49
Shimizu; Tatsuya.....................................................................21
Swartz; Michael E...................................................................65
Shmueli; Galit.........................................................................89
Swearengen; James R.............................................................50
Shrader; Stephen....................................................................41
Swing; Sonya P.......................................................................52
Sibold; Amber L......................................................................52
Symonds; Tara........................................................................64
Sidhu; Sachdev S....................................................................66
Szycher, Ph.D; Michael...........................................................25
Siegert; Richard......................................................................24 Silva; J. Paulo Sousa e.............................................................62 Silverman; Jerald.....................................................................51 Simon; Ted.............................................................................59 Simpson; Richard C................................................................16 Singh; Sunit K.............................................................50, 54, 59
T Taatjes; Douglas J....................................................................46 Tabakov; Slavik.................................................................17, 20 Takeyasu; Kunio......................................................................42 Tallarida; Ronald J...................................................................43 Tan; Jen Hong.........................................................................29
Author Index
Scalliet; Pierre.........................................................................23 Schäfers; Klaus........................................................................28
U Ude; George...........................................................................36 Umlauf; Anya..........................................................................72 Upton; Adrian.........................................................................18
V Vach; Werner..........................................................................74 Vaida; Florin ...........................................................................72 Vaidyanathan; Ravi.................................................................20 Valentine; David L...................................................................57 Valentine; Raymond C............................................................57 Vallet-Regí; María....................................................................15 Vallittu; Pekka.........................................................................26 van Buuren; Stef.....................................................................82 van de Weert; Marco..............................................................69 van der Marel; Gijsbert.............................................................3 van Houwelingen; Hans C......................................................73 Vanderlei Menani; Jose...........................................................56 Venselaar; Jack........................................................................28 Verbeke; Geert........................................................................83 Verhaegen; Frank....................................................................32 Verma; Mukesh.......................................................................36 Vert; Jean-Philippe .................................................................76 Via; Allegra.............................................................................71 Victor; Jonathan D..................................................................58 Vij; Neeraj...............................................................................23 Villano; Jason..........................................................................52
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101
Villena; Julio............................................................................38
Wszolek; Zbigniew K..............................................................58
Vizirianakis; Ioannis S..............................................................18
Wu; Chengtie.........................................................................11
Vo-Dinh; Tuan..................................................................15, 25
Wu; Chwan-Hwa (John)..........................................................89
Vytras; Karel............................................................................36
Wu; Guoyao.............................................................................3
W Waksmundzka-Hajnos; Monika...............................................68
Wu; Nianqiang.......................................................................43
X
Author Index
Walcarius; Alain......................................................................36
Xi; Ning..................................................................................78
Walker; John D.........................................................................5
Xi; Peng..................................................................................33
Wall; Michael E.......................................................................90
Xia; H. Amy............................................................................64
Wang; Bin...............................................................................38
Xiao; Yin.................................................................................11
Wang; Guanyu.......................................................................75
Xie; Xiaoliang Sunney.............................................................28
Wang; Jason T.L......................................................................75
Xie; Yihui................................................................................81
Wang; Ruikang K....................................................................27
Xie; Yubing.............................................................................46
Wang; Yu-Chao......................................................................78 Wang; Zhihui..........................................................................78 Watanabe; Mari......................................................................18 Wax; Adam.............................................................................19 Webster; Gregory K................................................................24 Webster; John G.....................................................................19 Webster; Thomas....................................................................25 Wegrzyn; Renee D..................................................................65 Weiner; Daniel........................................................................70 Welch; Kathleen B..................................................................85 Welch; Michael J.....................................................................34 Wen; Xuejun...........................................................................38 West; Brady T....................................................................80, 85
Y Yalkowsky; Samuel H..............................................................69 Yang; Sherry X........................................................................49 Yang; Yang.............................................................................79 Yevdokimov; Yuri M................................................................48 Yi; Dong Kee..........................................................................10 Yin; R.J....................................................................................71 Yoganathan; Ajit P...................................................................14 Youell; James..........................................................................46 Yu; Hanry...............................................................................30 Yu; Wenwei............................................................................12 Yuriev; Elizabeth.......................................................................7
Z
Weyer; Lois.............................................................................42 Wheeler; Matthew B...............................................................36 Wick; Charles H......................................................................40
102
Wide; Peter.............................................................................27 Wiens; Brian L.........................................................................64 Wiklund, P.E.; Michael E..........................................................11 Wilkinson; J. Malcolm.............................................................43 Willson; Keith.........................................................................20 Winkelstein; Beth A. ...............................................................22 Wong; Garry...........................................................................71 Wong; Jack.............................................................................18 Wong; Joyce Y...........................................................................7 Wood; Andrew W...................................................................23 Wood; Bernard A....................................................................88 Wood; Simon.........................................................................82
Zambare; Vasudeo..................................................................38 Zempleni; Janos........................................................................5 Zeng; Haishan........................................................................17 Zhang; Hao............................................................................19 Zhang; Jin-Ting.......................................................................80 Zhang; Lijie Grace..................................................................25 Zhang; Ming..........................................................................16 Zhang; Mingjun.....................................................................78 Zhang; Sam..............................................................................9 Zhou; Ruhong........................................................................90 Zhou; Yufeng..........................................................................23 Zinovyev; Andrei....................................................................76 Zou; Kelly H............................................................................64 Zucchini; Walter.....................................................................84
Woodward; Mark....................................................................73 Workman, Jr.; Jerry..................................................................42
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In the Americas Sales Office - CRC Press 6000 Broken Sound Parkway, NW, Suite 300, Boca Raton, FL 33487, U.S.A. Within the Continental USA - Tel: 800-272-7737 • Fax: 800-374-3401 • orders@taylorandfrancis.com Outside the Continental USA - Tel: 561-994-0555 • Fax: 561-361-6018 • international.orders@taylorandfrancis.com Dennis Weiss Tel: 561-998-2510 Fax: 561-998-2580 e-mail: dennis.weiss@taylorandfrancis.com
Customer Service/Sales Operation Angela Williams Tel: 800-272-7737 ext. 6091 Fax: 800-374-3401 e-mail: angela.williams@taylorandfrancis.com
Latin American Sales
Michael Dulisse Tel: 561-998-2582 Fax: 561-361-6049 e-mail: michael.dulisse@taylorandfrancis.com
Premium/Custom Sales
George Kenney Tel: 561-998-2544 Fax: 561-361-6049 e-mail: george.kenney@taylorandfrancis.com
eBooks and Digital Content Sales
Bookstores and Textbook Sales
Libraries
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Rosa Perez Tel: 917 351-7115 Fax: 212-244-1563 e-mail: rosa.perez@taylorandfrancis.com Evelyn Elias Tel: 561-361-6010 Fax: 561-361-6049 e-mail: evelyn.elias@taylorandfrancis.com
Evelyn Elias Tel: 561-361-6010 Fax: 561-361-6049 e-mail: evelyn.elias@taylorandfrancis.com Christina M. Taranto Tel: 212-216-7862 Fax: 212-244-1563 e-mail: christina.taranto@taylorandfrancis.com
Milton Park Sales Office - Taylor & Francis Group (Books Ltd) 2 Park Square, Milton Park, Abingdon, Oxon, OX14 4RN, UK
Group Sales Director
UK Sales Support Coordinator
Christoph Chesher Tel: +44 (0) 20 7017 6194 Fax: +44 (0) 20 7017 6748 e-mail: christoph.chesher@tandf.co.uk
Lindsey Binks Tel: +44 (0) 7017 7365 e-mail: lindsey.binks@tandf.co.uk
International Sales Director Graham Crossley Tel: +44 (0) 20 7017 6048 Fax: +44 (0) 20 7017 6748 e-mail: graham.crossley@tandf.co.uk
Head of UK Sales Nick Perry Tel: +44 (0) 20 7017 6132 Fax: +44 (0) 20 7017 6732 e-mail: nick.perry@tandf.co.uk
Corporate and Institutional Sales Alfred Lea Tel: +44 (0) 20 7017 6273 Fax: +44 (0) 20 7017 6732 e-mail: cis@tandf.co.uk
UK Sales Support Manager Jude Sermon Tel: +44 (0) 20 7017 6191 Fax: +44 (0) 20 7017 6732 e-mail: jude.sermon@tandf.co.uk
Central and South America and Mexico Michael Dulisse Sales Office, Boca Raton, FL Taylor & Francis 6000 Broken Sound Parkway, NW, Suite 300, Boca Raton, FL 33487, USA Tel: 561-998-2582 Fax: 561-361-6049 e-mail: michael.dulisse@taylorandfrancis.com Ethan E. Atkin (Excluding Brazil) Cranbury International LLC 7 Clarendon Ave, Suite 2 Montpelier, VT 05602, USA Tel: +1 802 223 6565 Fax: +1 802 223 6824 e-mail: eatkin@cranburyinternational.com
Taylor & Francis Group Brazil Renata Zanzini – Depto Comercial infobrasil@taylorandfrancis.com Tel: (11) 3017-6941 / (11) 97486-8236 Rua Bela Cintra, 967 – 11 and. 01415-000 – São Paulo – SP.
Academic Representatives (UK) Tim Page Higher Education Sales Manager Mobile: 07824 690646 e-mail: tim.page@tandf.co.uk
International Enquiries Joanne Blackford International Sales Support Manager (Books) Tel: +44 (0) 20 7017 6053 Fax: +44 (0) 20 7017 6748 e-mail: joanne.blackford@tandf.co.uk
Europe and Japan Enquiries Hannah Dolton International Sales Support Coordinator Tel: +44 (0) 20 7017 6149 Fax: +44 (0) 20 7017 6748 e-mail: hannah.dolton@informa.co.uk
South Asia, Middle East and Africa Enquiries Adrian Riddock International Senior Sales Support Coordinator Tel: +44 (0) 20 7017 6114 Fax: +44 (0) 20 7017 6748 e-mail: adrian.riddock@tandf.co.uk
China Liaison Office Leo Li Senior Manager - Academic Publishing Taylor & Francis Group, Beijing Office Room 1108B, Culture Square, No. 59 Jia, Zhongguancun St. Haidian District, Beijing 100872, P.R. China Tel: 8610–8250 3061 Li.Leo@tandf.com.sg
Customer Services Book orders should be addressed to the appropriate overseas agent or the Customer Service Department at Bookpoint:
Taylor & Francis Bookpoint 130 Park Drive, Milton Park Abingdon, Oxon OX14 4SE Tel: +44 (0) 1235 400 524 Fax: +44 (0) 1235 400 525 e-mail (UK): uktrade@tandf.co.uk e-mail (international): international@tandf.co.uk
Standing Orders
If you would like to receive books on our improved preselective standing order system, or if you would like to have further information about this service, please contact your area manager or Customer Services Department.
Foreign Rights Adele Parker e-mail: adele.parker@tandf.co.uk
103
Exhibitions Katie Gilbert Exhibitions Manager Tel: +44 (20) 7017 6310 e-mail: katie.gilbert@tandf.co.uk
Caribbean and The West Indies
Middle East and South Africa
Rest of Africa
Jasmina Basic Area Sales Manager Milton Park Sales Office Tel: +44 (0) 20 7017 6187 Fax: +44 (0) 20 7017 6748 e-mail: jasmina.basic@tandf.co.uk
Jasmina Basic Area Sales Manager – Middle East and South Africa Milton Park Sales Office Tel: +44 (0) 20 7017 6187 Fax: +44 (0) 20 7017 6748 e-mail: jasmina.basic@tandf.co.uk Zoe Kaviani IPS (Middle East) Ltd P.O. Box 27533 Dubai, UAE Tel: +971 4 238 4001 Fax: +971 4 238 4005 e-mail: itpme@emirates.net.ae Website: http://www.ipsme.com
Adrian Riddock International Senior Sales Support Coordinator e-mail: adrian.riddock@tandf.co.uk
Australasia Joanne Blackford Milton Park Sales Office Tel: +44 (0) 20 7017 6053 Fax: +44 (0) 20 7017 6748 e-mail: joanne.blackford@tandf.co.uk
Australia Europa Publications (non-exclusive) James Bennett 3 Narabang Way, Belrose, NSW 2085 Australia Tel: +02 9986 7064 Fax: +02 9986 7030 www.bennett.com.au
Sales Agents
Senior Vice President of Sales
Sub-Saharan Africa (excluding South Africa and Botswana) Julian Russ Tula Publishing Ltd Aristotle House Aristotle Lane Oxford OX2 6TR Tel: +44 (0) 1865 553606 Fax: +44 (0) 1865 517999 e-mail: julian@tulapublishing.co.uk
Sales Agents
Botswana
East and Southeast Asia
Arthur Oageng Book Promotions/Horizon Books Botswana Gaborone International Finance Park Plot 113-114, Unit 33, Kgale Mews 2, Suite 3 Gaborone, Botswana Tel: +267 393 1194 Fax: +267 392 4908 e-mail: arthur.oageng@online.co.bw
For all Taylor & Francis Group imprints please order from our Singapore Sales Office Singapore Sales Office Taylor & Francis Asia Pacific 60 MacPherson Road #06-09 Siemens Centre Singapore 348615 Fax: +65 6742 9356 e-mail: sales@tandf.com.sg
Taylor & Francis Asia Pacific Jeffrey Lim Books Sales Director e-mail: jeffrey.lim@tandf.com.sg Nonglak Sawaithong Account Manager Tel : +66 2 639 1333 ext. 3612 e-mail: s.nonglak@tandf.com.sg
Hong Kong
Taylor & Francis Asia Pacific Room 629, 6F, No. 6, Sec. 4, Hsinyi Road Da-an District Taipei 106 Taiwan (R.O.C.) Jeffrey Lim Books Sales Director e-mail: jeffrey.lim@tandf.com.sg Jason Lin Sales Manager Tel: +886 (2) 25551 1266 ext 6291 e-mail: Jason.Lin@tandf.com.sg
South Africa, Namibia, Lesotho and Swaziland Michelle Symington Book Promotions/Horizon Books PO Box 6836 Roggebaai 8012 South Africa Tel: +27 21 469 8900 Fax: +27 21 469 8903 Fax2Email: 0865314387 e-mail: enquiries@bookpro.co.za
South Asia Ryan Cooper International Sales Manager Milton Park Sales Office Tel: +44 (0) 20 7017 6113 Fax: +44 (0) 20 7017 6748 e-mail: ryan.cooper@tandf.co.uk
India Taylor & Francis Books India Pvt Ltd. 912 Tolstoy House 15-17, Tolstoy Marg New Delhi 110 001 Tel: +91 (0) 11 2371 2131 +91 (0) 11 2335 1453 Fax: +91 (0) 11 2371 2132 e-mail: inquiry@tandfindia.com
Pakistan
104
M. Anwer Iqbal Book Bird Mian Chambers, 3 Temple Road PO Box 518, Lahore, Pakistan Tel: +92 42 636 7275 Fax: +92 42 636 1370 e-mail: bookbird@brain.net.pk
Japan United Publishers Services Limited 1-32-5 Higashi-shinagawa Shinagawa-ku, Tokyo 140-0002 Tel: +81 (0) 3 5479 7251 Fax: +81 (0) 3 5479 7307 e-mail: info@ups.co.jp Editorial Office
Korea Se-Yung Jun ICK (Information & Culture Korea) 473-19 Seokyo-dong, Mapo-ku Seoul, Korea 121-896 Tel: +82 2 3141-4791 Fax: +82 2 3141-7733 e-mail: cs.ick@ick.co.kr
Taylor & Francis Asia Pacific Suite 145, Somptueux Central 52-54 Wellington Street Central Hong Kong Tel: +852 3752 0626 Jeffrey Lim Books Sales Director Singapore Sales Office e-mail: jeffrey.lim@tandf.com.sg Andrew Kwan Manager e-mail: andrew.kwan@tandf.com.sg
China
Taylor & Francis Asia Pacific Room 1108B, Culture Square No. 59 Jia, Zhongguancun St. Haidian District Beijing 100872 P.R. China Tel: +86 10 82502670 Fax: +86 10 82502566 Jeffrey Lim Books Sales Director Singapore Sales Office e-mail: jeffrey.lim@tandf.com.sg Cynthia Ji Sales Manager e-mail: cynthia.ji@tandf.com.sg
Shanghai Region
Chris Ye Account Manager Room 1410, Jinjiang Xiangyang Tower 993 Nanjing West Road Shanghai 200041 P.R. China Tel: +86 21 22111595 e-mail: chris.ye@tandf.com.sg
Guangdong Region
Cherry Wang Sales Executive e-mail: cherry.wang@tandf.com.sg
Singapore and Indonesia
Mohamed Feroz Assistant Sales Manager Singapore Sales Office e-mail: mohamed.feroz@tandf.com.sg
Malaysia and Brunei
Taylor & Francis Publishing Services Taylor & Francis Asia Pacific No. 23-2, Jalan PJS 8/18 Dataran Mentari 46150 Petaling Jaya Selangor Darul Ehsan Malaysia Tel: +60 (3) 5630 1361 Fax: +60 (3) 5630 1732 David Yeong General Manager Mobile: +60 (0)16 331 9912 e-mail: david.yeong@tandf.com.sg
Thailand
Taiwan
Philippines, Vietnam and Indo-China Jeffrey Lim Books Sales Director Singapore Sales Office e-mail: jeffrey.lim@tandf.com.sg
Israel and the Palestinian Territories Ryan Cooper International Sales Manager Milton Park Sales Office Tel: +44 (0) 20 7017 6113 Fax: +44 (0) 20 7017 6748 e-mail: ryan.cooper@tandf.co.uk and Rodney Franklin Franklin’s International PO BOX 3772 7, Tel Aviv 61376, Israel Tel: +972 356 00724 Fax: +972 356 00479 e-mail: rodneyf@netvision.net.il
Europe Belgium, The Netherlands, France and Luxembourg Liza Walraven Area Sales Manager Taylor & Francis P.O. Box 447 2300 AK Leiden The Netherlands Tel. 0031 (0) 715243084 F: 0031 (0) 71 523 4571 Mobile: 0031 (0)623849668 e-mail: liza.walraven@informa.com
Nordic Countries Eva Nyika Sales Representative Taylor & Francis Scandinavia Kungsbroplan 3 A, 1st Floor P.O Box 3255 SE-103 65 Stockholm, Sweden e-Mail eva.nyika@tandf.co.uk
Germany, Austria and Switzerland Gabriela Mauch Area Sales Manager
Taylor & Francis Group (Books Ltd)
Karlshofstr. 22 70599 Stuttgart, Germany Tel: +49 (0)711 7207231 Fax: +49 (0)711 7220668 Mobile +49 (0)173 9059469 e-mail: gabriela.mauch@tandf.co.uk
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