Biotechnology Books - November 2010

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Contents Nanobiotechnology ..........................................3 Drug Discovery ................................................7 Biotechnology ..................................................8 Biochemistry ..................................................13 Page 3

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Biomaterials & Medical Devices ......................14 Bioengineering................................................17 Industry Applications ......................................18 Bioprocessing..................................................20 Math for Engineers ........................................22 Page 7

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Nanobiotechnology New! New!

Biomedical Microsystems Ellis Meng University of Southern California, Los Angeles, USA

Poised to dramatically impact human health, biomedical microsystems (bioMEMS) technologies incorporate various aspects from materials science, biology, chemistry, physics, medicine, and engineering. Reflecting the highly interdisciplinary nature of this area, Biomedical Microsystems covers the fundamentals of miniaturization, biomaterials, microfabrication, and nanotechnology, along with relevant applications. Written by an active researcher who was recently named one of Technology Review’s Young Innovators Under 35, Biomedical Microsystems focuses on the integration of multiple modalities in miniaturized devices for use in fundamental scientific research, biomedical diagnostics, and therapy. The author introduces materials, fabrication technology, and the necessary components of bioMEM, and covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering. Detailed examples, exercises, and illustrations help elucidate the concepts. For readers with a limited background in MEMS and bioMEMS, this book provides a practical introduction to the technology used to make these devices, the principles that govern their operation, and examples of their application. It offers a starting point for understanding advanced topics and encourages readers to begin to formulate their own ideas about the design of novel bioMEMS. Catalog no. 51229, September 2010, 408 pp. ISBN: 978-1-4200-5122-3, $89.95 / £49.99

Nanotechnology in Tissue Engineering and Regenerative Medicine Edited by

Ketul Popat Referred to as "nanomedicine" or "nanobiomedicine," the application of nanotechnology to medicine can impact diagnosis, monitoring, and treatment of diseases as well as control and understanding of biological systems. Bringing together an unparalleled field of experts, this volume explores various aspects of nanotechnology and its applications in biomedical fields. The book uses an application-oriented approach to relate laboratory-based research to the development of technologies that can be readily adaptable to an industrial environment, focusing chiefly on drug delivery, tissue engineering, and regenerative medicine. Contents: Atomic Force Microscope Lithography on Biomimetic Surfaces. Nanofiber-Based Integrative Repair of Orthopedic Soft Tissues. Polycaprolactone Nanowires for Controlling Cell Behavior at the Biointerface. Electrospun Nanofibers for Neural Applications. Mixed Monolayer System of Mercaptobenzoic Acid and Polyethylene Glycol for pH Sensing: Surface-Enhanced Raman Scattering Studies. Nano-Enabled Platforms for Metastatic Malignant Melanoma. Immune Response to Implanted Nanostructured Materials Enhanced Cell Growth, Function, and Differentiation by TiO2 Nanotube Surface Structuring. Electrospun Pseudo Poly (Amino Acids) for Tissue Engineering Applications. Nanotechnologies for Peripheral Nerve Regeneration. Nanoscale Control of Cell– Substrate Adhesion. Nanofibrous Materials for Vascular Tissue Engineering and Regeneration. Engineering Soft Nanostructures for Guided Cell Response. Nanoparticles-Incorporated Scaffolds for Tissue Engineering Applications. Catalog no. K10090, November 2010, c. 292 pp. ISBN: 978-1-4398-0141-3, $119.95 / £72.00

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Nanobiotechnology New!

Bestseller!

Medical Nanotechnology and Nanomedicine

Introduction to Nanoscience and Nanotechology

Harry F. Tibbals University of Texas Southwestern Medical Center, Dallas, USA Series: Perspectives in Nanotechnology

This accessible guide reviews advances in nanoscience and nanotechnology and examines their applications in medicine. Providing an introduction to both the science and the infrastructure required to support these advances, this volume is written for non-experts, which can include medical researchers, students, and clinicians as well as those concerned with business aspects, regulation, and the administration of medical practices. The book provides a contextual background including history, definitions, and recent trends and investigates current and future nanotech applications in medicine and the biomedical sciences. A highly accessible overview of alternative and conflicting concepts in the rapidly developing nanotechnology revolution, this friendly guide reviews current research and development in nanoscience and illustrates the accomplishments and possibilities for application in nanomedicine. Divided into three parts, the first presents an historical background, the second investigates the current status of the field and its applications, and the third looks provides potential prospects of nanotechnology and its impact on medicine and health in the broadest sense. References and sources are given for those who wish to pursue an in-depth study on techniques, instruments, and practices Part of the Perspectives in Nanotechnology series—which contains broader coverage of the societal implications of nanotechnology—this book can be used as a standalone reference. Catalog no. K10431, September 2010, 527 pp. Soft Cover, ISBN: 978-1-4398-0874-0 $69.95 / £44.99

Gabor L. Hornyak, John J. Moore, H.F. Tibbals, and Joydeep Dutta The archetype of the modern nano textbook, Introduction to Nanoscience and Nanotechnology builds a solid background in characterization and fabrication methods while integrating the physics, chemistry, and biology facets. The remainder of this text focuses on applications, examining engineering aspects as well as nanomaterials and industry-specific applications in such areas as energy, electronics, and biotechnology. Catalog no. 47795, 2009, 1,574 pp. ISBN: 978-1-4200-4779-0, $141.00 / £80.99

Also available in two course specific volumes

Introduction to Nanoscience Introduction to Nanoscience elucidates the nanoscale along with the societal impacts of nanoscience, then presents an overview of characterization and fabrication methods. The authors systematically discuss the chemistry, physics, and biology aspects of nanoscience, providing a complete picture of the challenges, opportunities, and inspirations posed by each facet before giving a brief glimpse at nanoscience in action: nanotechnology. Catalog no. 48058, 2009, 856 pp. ISBN: 978-1-4200-4805-6, $89.95 / £40.99

Fundamentals of Nanotechnology A 2009 winner of the CHOICE award for outstanding academic title, Fundamentals of Nanotechnology surveys the field’s broad landscape, exploring the physical basics such as nanorheology, nanofluidics, and nanomechanics as well as industrial concerns such as manufacturing, reliability, and safety. The authors then explore the vast range of nanomaterials and systematically outline devices and applications in various industrial sectors. This color text is an ideal companion to Introduction to Nanoscience by the same group of esteemed authors. Catalog no. 48031, 2009, 786 pp. ISBN: 978-1-4200-4803-2, $89.95 / £40.99

Color illustrations and a wealth of pedagogical tools are available online for each of the three books.

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Nanobiotechnology Particulate Systems in Nano- and Biotechnologies

Forthcoming!

Bionanotechnology II Global Prospects

Edited by

Edited by

Wolfgang Sigmund, Hassan El-Shall, Dinesh O. Shah, and Brij. M. Moudgil

David E. Reisner

University of Florida, Gainesville, USA

Viewing recent advancements in absorbed films and particle technology as a foundation for nanoand biotechnology innovations, Particulate Systems in Nano- and Biotechnologies offers comprehensive coverage of important topics in this area and summarizes developments occurring worldwide over the past decade. International experts from European, Australian, Asian, and North American research centers—including the National Science Foundation's Engineering Research Center for Particle Science and Technology—offer critical perspectives in relation to each of their specific research areas, examine the current status of technology, and define the challenges that future research must address.

The Nano Group, Inc., Farmington, Connecticut, USA

A blend of information from the Biomedical Engineering Handbook and new material, this book draws on the experience of experts from countries such as Iran, Cuba, South Africa, UK, Canada, China, India, and Russia. It reflects the increasing emphasis and importance of nanomedicine and biotechnology with the inclusion of topics such as Biomimicry, Stem Cells, Optical Togs, Nanocoating for Medical Implantable Devices, Food Industry, Cosmetics, Cardiac Diagnosis, Batteries, Drug Delivery, Photonics, DNA Building Blocks, Protein Devices, Quantum Dots, Bioanalysis, Optics, Nanomedicine, Personalized Medicine and the Business of Emerging Bionanotech Companies. Catalog no. K10254, January 2011, 350 pp., ISBN: 978-1-4398-0463-6, $99.95 / £63.99

Catalog no. 7436, 2009, 385 pp. ISBN: 978-0-8493-7436-4, $157.95 / £99.00

Nano- and Biocomposites Edited by

Alan Kin-tak Lau, Farzana Hussain, and Khalid Lafdi This compilation is divided into two sections — Nanostructured Polymer Composites and Nano-Bio Composites. These section provides enough background on nanomaterial and nanocomposite research to explain the fundamentals of how nanostructured fillers strengthen polymer-based materials. With an emphasis on how nano- and biocomposites are used to create new biomedical applications, the text also focuses on the crucial yet often-ignored potential toxicity impact of using nanostructured materials. It presents important guidelines and new insights to stimulate investigation of anticipated research in this fascinating new field. Researchers, scientists, and academics will all appreciate this cutting-edge exploration of nanomaterials, biomaterials, and the ever-evolving world of nano-biomaterials. Catalog no. 8027X, January 2010, 408 pp. ISBN: 978-1-4200-8027-8, $159.95 / £99.00

Bionanotechnology Global Prospects Edited by

David E. Reisner The Nano Group, Inc., Farmington, Connecticut, USA

As the impact of nanotechnology continues to grow, it is important for the modern biomedical engineer to have a deeply rooted understanding of bionanotechnologies. Featuring chapters drawn from the third edition of the best-selling Handbook of Biomedical Engineering as well as new contributions not found in the Handbook, Bionanotechnology takes a broad survey of the current research and activities that are shaping this burgeoning field. Covering both technical and non-technical areas, the book discusses the role of nanotechnology in novel medical devices, bioanalytical technologies, and nanobiomaterials as well as intellectual property issues that are unique to nanotechnologies. Catalog no. 7528, 2009, 368 pp. ISBN: 978-0-8493-7528-6, $94.95 / £60.99

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Nanobiotechnology Bestseller!

New!

Nanotechnology in Biology and Medicine

Bionanotechnology

Methods, Devices, and Applications Edited by

Tuan Vo-Dinh Duke University, Durham, North Carolina, USA

"Overall, this book with contributions by 96 authors from a broad range of disciplines is a valuable resource for everyone interested in this exciting interdisciplinary field, where nanotechnology and optics meet biology and medicine." —Katrin Kneipp, Harvard University Medical School and Harvard-MIT Division of Health Sciences and Technology, in Angewandte Chemie, 2008, Vol. 47, No. 13

"… an in-depth assembly of essays concerning the practice of nanotechnology in life sciences. Blackand-white diagrams and photographs enhance this highly detailed resource recommended for professionals in the field … as well as for students and educators." —James A. Cox in a Midwest Book Review, June 2008

The latest generation of nanodevices enables scientists to more accurately detect, analyze, and manipulate nanostructures at the molecular level. With emphasis on the application and design of nanomaterials, devices, and sensors, this book carefully details current methods, protocols, and instrumentation for biomedical applications including stem cell research, gene diagnostics, targeted drug delivery, and tissue engineering. Pioneers in the field offer a cohesive compilation of data, practical tool kits, references, and experimental insight on relevant topics including self-assembly, bio-inspired materials, and biomanufacturing. Catalog no. 2949, 2007, 792 pp. ISBN: 978-0-8493-2949-4, $162.95 / £99.00

Maheshwar Sharon IIT Bombay (retired), Birla College, Nanotechnology Research Center

Madhuri Sharon Monad Nanotech Pvt. Limited, Mumbai, India

Bionanotechnology focuses on all fundamental bionanomachines including their applications towards the service of humankind. These bionanomachines, such as DNA, RNA, Proteins, Carbohydrates, and Lipids constitute the engines or raw materials of nearly all biosystems. This book is a distillation of the author’s research and experimentation gathered while doing groundbreaking research in the field of bionanotechnology. It represents a well documented and researched overview of how nanoscale technologies may enhance our lives, health, and significantly change the world we live in. Catalog no. K12393, March 2011, 300 pp. ISBN: 978-1-4398-5214-9, $79.95 / £49.99

Nanoparticulate Drug Delivery Systems Edited by

Deepak Thassu, Michel Deleers, and Yashwant Vishnupant Pathak Series: Drugs and the Pharmaceutical Sciences

"…includes a wealth of latest advances in the technology of nanoparticulates…" —Professor Gregory Gregoriadis, The School of Pharmacy, University of London and Lipoxen Plc, London, UK (from the Forward)

Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. This expertly written guide addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS, including lipid nanoparticles for dermal applications, nanocarriers for the treatment of restenosis, ocular, central nervous system, and gastrointestinal applications, and use of NPDDs as an adjuvant for vaccine development. Catalog no. 9073, 2007, 376 pp. ISBN: 978-0-8493-9073-9, $230.00 / £115.00

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Drug Discovery New!

New!

3D Cell-Based Biosensors in Drug Discovery Programs

Neurobiology of Huntington’s Disease

Microtissue Engineering for High Throughput Screening William S. Kisaalita University of Georgia, Athens, USA

Advances in genomics and combinatorial chemistry during the past two decades inspired innovative technologies and changes in the discovery and pre-clinical development paradigm with the goal of accelerating the process of bringing therapeutic drugs to market. Written by William Kisaalita, one of the foremost experts in this emerging field, 3D Cell-Based Biosensors in Drug Discovery Programs: Microtissue Engineering for High Throughput Screening provides the latest information — from theory to practice — on challenges and opportunities for incorporating 3D cell-based biosensors or assays in drug discovery programs. Dr. Kisaalita presents evidence in support of embracing 3D cell-based systems for widespread use in drug discovery programs. He goes to the root of the issue, establishing the 3D cell-based biosensor physiological relevance by comparing 2D and 3D culture from genomic to functional levels. He then assembles the bioengineering principles behind successful 3D cell-based biosensor systems. Kisaalita also addresses the challenges and opportunities for incorporating 3D cell-based biosensors or cultures in current discovery and pre-clinical development programs. This book makes the case for widespread adoption of 3D cell-based systems, rendering their 2D counterparts, in the words of Dr. Kisaalita, “quaint, if not archaic” in the near future. Catalog no. 73494, June 2010, 404 pp. ISBN: 978-1-4200-7349-2, $129.95 / £82.00

Applications to Drug Discovery Edited by

Donald C. Lo Duke University Medical Center, Durham, North Carolina, USA

Robert E. Hughes Buck Institute for Age Research, Novato, California, USA Series: Frontiers in Neuroscience

Neurobiology of Huntington’s Disease: Applications to Drug Discovery presents a thorough review of the issues surrounding drug discovery and development for the treatment of this paradigmatic neurodegenerative disease. Drawing on the expertise of key researchers in the field, the book discusses the basic neurobiology of Huntington’s disease and how its monogenic nature confers enormous practical advantages for translational research, including the creation of robust experimental tools, models, and assays to facilitate discovery and validation of molecular targets and drug candidates for HD. Highlighting advances in the discovery and development of new drug therapies for neurodegenerative disorders, Neurobiology of Huntington's Disease focuses on the many aspects of the research on drugs to treat Huntington's disease. It discusses genetics, genomics, and proteomics, and the latest in high-throughput and high-content screening. The authors provide introductory background as well as highly sophisticated information on current and future directions of research. Exploring the interplay between academic and industrial research, the investment community, and nonprofit contributors, the book also examines the practical realities of preclinical testing, clinical testing strategies, and, ultimately, clinical usage. Catalog no. 9000, July 2010, 338 pp. ISBN: 978-0-8493-9000-5, $149.95 / £95.00

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Drug Discovery Fundamentals of Microfluidics and Lab on a Chip for Biological Analysis and Discovery Paul C.H. Li Simon Fraser University, Burnaby, British Columbia, Canada

Authored by one of the field’s pioneering researchers, this volume focuses on all key aspects of the microfluidic lab-on-a-chip technologies to offer an exceptionally cohesive overview of the science, its limitations, breakthroughs made over the years, and currently emerging advances. The book emphasizes analytical applications of microfluidic technology and presents in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays, and enzymatic assays.

Biotechnology

New!

Adhesion Molecules Victor R. Preedy King's College, London, UK

This book covers the structure and classification of adhesion molecules, immunohistochemical localization, junctional, functional and inflammatory adhesion molecules, and molecular imaging. It discusses adhesion molecules in relation to signaling pathways, gene expression, arginine, stem cells, neutrophil migration, leukocytes decompression sickness, ischemia reperfusion injury, diabetes, obesity, metabolic syndrome, weight loss, hypoxia, kidney disease, smoking, osteoprotegerin, tumors, bioinformatics, high-throughput technologies, chemotherapy, hematopoiesis, lipoproteins, fatty acids, atrial fibrillation and heart disease, and the brain and dementia. Catalog no. N10265, April 2010, 520 pp. ISBN: 978-1-57808-671-9, $149.95 / £95.00

Catalog no. K10977, February 2010, 418 pp. Soft Cover, ISBN: 978-1-4398-1855-8 $99.95 / £38.99

Drug Device Combination Products Delivery Technologies and Applications Edited by

A Lewis Biocompatibles, UK

Introduction to Biology and Biotechnology, Second Edition K. Vaidyanath, K. Pratap Reddy, and K. Satya Prasad

Drug delivery systems represent a vast area of research and development within biomaterials and medicine and the demand for sophisticated drug delivery devices continues to drive novel product development. This book illustrates how effective drug delivery can be achieved by means other than oral tablets. Written by an international team of experts, this book provides a thorough analysis of the fundamentals, applications, and new technologies of drug-device combination products for use throughout the human body. Topics featured include background information, areas of application and the development of drug device combination products.

Including recent advances, this edition focuses on sustainable development and human welfare in biology, genetics, microbial biotechnology, and molecular medicine. While written for engineers specializing in biotechnology, those in agriculture, veterinary science, and medicine, will find new information relevant to their practice. It links biological principles to plant, animal, environmental, industrial, and medical biotechnologies, discusses concepts of genetics and molecular biology, and examines developments in the production of biopolymers, vaccines, gene therapy, bioremediation, biofuels, and biofertilizers.

Catalog no. N10136, January 2010 ISBN: 978-1-4398-2479-5, $244.99 / £155.00

Catalog no. N10069, 2009, 625 pp. ISBN: 978-1-4398-0724-8, $79.95 / £41.99

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Biotechnology

New!

Biology for Engineers Arthur T. Johnson University of Maryland, College Park, USA

Biology is a critical application area for engineering analysis and design, and students in engineering programs must be well-versed in the fundamentals of biology as they relate to their field. Biology for Engineers is an introductory text that minimizes unnecessary memorization of connections and classifications, instead emphasizing concepts, technology, and the utilization of living things. Classroom-tested at the University of Maryland, this comprehensive text introduces concepts and terminology needed to understand more advanced biology literature. Filled with practical detailed examples, the book presents: • Scientific principles relevant to biology that all engineers must know • A discussion of biological responses from the perspective of a broad range of fields such as psychology, human factors, genetics, plant and animal physiology, imaging, control systems, actuary, and medicine • A thorough examination of the scaling of biological responses and attributes • A classification of different types of applications related to biological systems • Tables of useful information that are nearly impossible to find elsewhere Emphasizing the ever-present interactions between a biological unit and its physical, chemical, and biological environments, the book provides ample instruction on the basics of physics, chemistry, mathematics, and engineering. It brings together all of the concepts one needs to understand the role of biology in modern technology.

New!

Environmental Microbiology for Engineers Volodymyr Ivanov Nanyang Technological University, Singapore

Environmental Microbiology for Engineers is specifically intended for undergraduate and graduate students from civil and environmental engineering and polytechnic schools and universities. It covers essential topics such as diversity and functions of microorganisms in environmental engineering systems, environmental bioengineering processes, applied microbial genetics and molecular biology, microbial biodegradation of organic substances, public health microbiology for environmental engineers, microbiology of water and wastewater treatment, and biotreatment of solid waste and soil bioremediation, as well as essential topics for civil engineering processes such as biodeterioration, biocorrosion, and biocementation. Each chapter includes quizzes and tutorials with instructor’s solutions available in a separate solutions manual with qualifying course adoption. To enhance this understanding of microbial functions in engineering systems, the authors have provided a tutorial bank, a quiz bank, and an exam question bank, as well as the solutions to these tutorial and exam questions in the solutions manual. The principal intention of this solutions manual is to help readers formulate answers to quantitative bioengineering and microbiological questions and to perform design calculations. Catalog no. 92340, November 2010, c. 438 pp. ISBN: 978-1-4200-9234-9, $99.95 / £63.99

Catalog no. 77635, September 2010, 775 pp. ISBN: 978-1-4200-7763-6, $99.95 / £44.99

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Biotechnology Smart Polymers Applications in Biotechnology and Biomedicine, Second Edition Edited by

Igor Galaev and Bo Mattiason

Illustrated Dictionary of Biotechnology Himanshu Arora

Lund University, Sweden

Ane Books, India

The first book to tackle the application of smart polymers in bioseparation and bioprocessing, Smart Polymers: Applications in Biotechnology and Biomedicine broke new ground in this challenging field. Completely revised, updated, and following in the footsteps of its predecessor, the second edition is poised to take its place as a premier reference in this field. This book addresses the major developments in the field that have taken place since the previous edition. Although polymers have always been considered passive participants, the second edition of this text promotes a more active role for smart polymers within the process of bioseparation than previously envisioned. With contributions from leading researchers as well as extensive end-of-chapter references, this volume offers a comprehensive overview of the current state-ofthe-art in the field and the potential for future developments.

Helping support a common language in this rapidly evolving field, the Illustrated Dictionary of Biotechnology includes a range of terms wide enough to satisfy the needs of any researcher, clinician, lawyer, investor, student, or instructor whose work involves contact with new advances in science and medicine. In clear and lucid English, it provides straightforward definitions and invaluable background information so that even complex terms require only a rudimentary understanding of the life sciences. Extensive cross-referencing expands individual definitions, enable readers to follow a chosen theme.

Catalog no. 9161, 2008, 496 pp. ISBN: 978-0-8493-9161-3, $139.95 / £90.00

New!

Bioseparation Technology Neeraj Mishra and Akhilesh Dubey Ane Books, India

Designed for those with a background in engineering or biology, this text explores the fundamentals of the emerging field of bioseparation technology. It begins with an introduction to bioprocesses and then provides focused chapters on cell disruption, filtration, centrifugation, adsorption, and extraction. The book also examines membrane separation processes, precipitation, chromatography, electrokinetic methods of separation, and finishing operations and formulation. Catalog no. N10039, September 2010 300 pp., Soft Cover, ISBN: 978-1-4398-0172-7 $49.95 / £31.99

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Catalog no. N10040, 2009, 450 pp. Soft Cover, ISBN: 978-1-4398-0173-4 $59.95 / £38.99

Essentials of Biotechnology R.C. Sobti and Suparna S. Pachouri Punjab University, India

A comprehensive treatise on biotechnology, this volume starts with an overall review of early applications that scientists employed long before the field was defined. It then moves on to examine the emergence of current methods and specialized tools in the field, as well as cell culture and nucleic acid based technologies. It devotes individual chapters to biotechnology in the areas of health, agriculture, environment, aquaculture, and food. These are followed by chapters on the status of biotechnology in developing countries with special reference to India. It also discusses debated ethical considerations and explores ongoing issues regarding intellectual property rights and patents. Catalog no. AB8284, 2009, 750 pp. ISBN: 978-1-4200-8284-5, $125.95 / £79.99

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Biotechnology New!

Macroporous Polymers

Sensors for Chemical and Biological Applications

Production Properties and Biotechnological /Biomedical Applications

Edited by

Edited by

Manoj Kumar Ram and Venkat R. Bhethanabotla

Bo Mattiasson and Igor Yu. Galeaev

University of South Florida, Tampa USA

Lund University, Sweden

This reference supplies versatile, hands-on tools for professionals working in a broad array of disciplines. Sensors for Chemical and Biological Applications offers a detailed discussion of the potential of chemical and biochemical sensors in medical science, food quality, biological, and environmental applications. Examining the role of nanotechnology in sensor development, it explores how sensors confront challenges of chemical-bioterrorism through enhanced specificity, fast response times, and the ability to determine multiple hazardous substances, and includes practical examples of sensor usage such as cholesterol monitoring along with extensive references. Exploring the nanotechnology approach and carrying this theme throughout the book, the chapters cover the sensing principles for chemical, electrical, chromatographic, magnetic, biological, fluidic, optical, and ultrasonic and mass sensing systems. The authors address issues associated with cost, synthesis, and testing of new low cost materials with high sensitivity, selectivity, robustness, and speed for defined sensor applications. The book extensively discusses the detailed analysis of future impact of chemical and biological sensors in day-to-day life. This reference not only supplies versatile, handson tools useful in a broad array of disciplines, but also lays the interdisciplinary groundwork required for the achievement of sentient processing. Catalog no. 3366, April 2010 390 pp. ISBN: 978-0-8493-3366-8, $129.95 / ÂŁ82.00

Ashok Kumar Indian Institute of Technology, Kampur, India

Macroporous polymers are rapidly becoming the material of choice for many tissue engineering, bioseparation, and bioprocessing applications. However, while important information is scattered about in many different publications, none, to date, have drawn this information together in user-friendly format. Until now. Meeting the need for an accessible, organized resource, Macroporous Polymers: Production Properties and Biotechnological/Biomedical Applications supplies a systematic presentation of the production, characterization, and application of these polymers. The editors bring together different viewpoints, summarize state-of-theart achievement, and cover applications in biotechnology, downstream processing, and biomedicine. They have collected the latest research and molded it into a cohesive reference, closing the gap between macromolecular design and production of these gels/polymers and their possible applications. The text discusses traditional methods of production, including phase separation polymerization, leaching, foaming, and double emulsion as well as newly merging methods such as cryogelation. The chapters also detail the various applications of macroporous gels for the separation of biomolecules and for the cultivation of mammalian cells in bioreactors and for tissue engineering. The book underscores existing and potential problems while providing a solid background on which to base the evaluation of the scientific and commercial value of new developments. Catalog no. 84615, January 2010, 525 pp. ISBN: 978-1-4200-8461-0, $129.95 / ÂŁ82.00

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Biotechnology Systems Biology and Bioinformatics A Computational Approach Kayvan Najarian Virginia Commonwealth University, Richmond, USA

Siamak Najarian and Shahriar Gharibzadeh Amirkabir University of Technology, Tehran, Iran

Christopher N. Eichelberger University of North Carolina, Charlotte, USA

The availability of molecular imaging and measurement systems enables today’s biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods used in what is being coined the digital era of biology. Written by field experts with proven track records, this authoritative textbook first provides an introduction to systems biology and its impact on biology and medicine. The book then reviews the basic principles of molecular and cell biology using a system-oriented approach, with a brief description of the high-throughput biological experiments that produce databases. The text includes techniques to discover genes, perform nucleotide and amino acid sequence matching, and estimate static gene dynamic pathways. The book also explains how to use system-oriented models to predict the behavior of biological systems for important applications such as rational drug design. The numerous examples and problem sets allow students to confidently explore practical systems biology applications using real examples with real biological data, making Systems Biology and Bioinformatics: A Computational Approach an ideal text for senior undergraduate and firstyear graduate students. Catalog no. 46500, 2009, 190 pp. ISBN: 978-1-4200-4650-2, $69.95 / £44.99

New!

Digital Microfluidic Biochips Design Automation and Optimization Krishnendu Chakrabarty Duke University, Durham, North Carolina, USA

Tao Xu Cisco Systems, Cary, North Carolina, USA

Microfluidics-based biochips combine electronics with biochemistry for newly emerging application areas such as point-of-care medical diagnostics, on-chip DNA analysis, automated drug discovery, and protein crystallization. This book envisions an automated design flow for microfluidic biochips. It offers newly designed automation solutions for problems unique to digital microfluidics. The authors provide a comprehensive methodology for the automated design, test, and use of robust and low-cost manufactured digital microfluidic systems. Using real-life bioassays as examples, they offer a comprehensive set of practical methodologies and tools for chip design and manufacture. Catalog no. K11010, May 2010, 213 pp. ISBN: 978-1-4398-1915-9, $139.95 / £89.00

New!

Electronics for Radiation Detection Edited by

Krzysztof Iniewski CMOS Emerging Technologies Inc., Vancouver, British Columbia

This book addresses the state of the art in the design of semiconductor detectors and integrated circuits, in the context of medical imaging using ionizing radiation. It explains how circuits for radiation are built, focusing on practical information about how they are being used, rather than mathematical details. It also discusses new opportunities in X-ray detection, computer tomography, and nuclear medicine. Written by industrial and academic experts, the text also explores emerging detector technologies, circuit design techniques, new materials, and innovative system approaches. Catalog no. K10847, July 2010, 378 pp. ISBN: 978-1-4398-1648-6, $149.95 / £95.00

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Biochemistry New!

Application of Solution Protein Chemistry to Biotechnology

Handbook of Aqueous Solubility Data Second Edition Samuel H. Yalkowsky University of Arizona, Tucson, USA

Roger L. Lundblad

Yan He

Lundblad Biotechnology, Chapel Hill, North Carolina, USA

Sanofi-Aventis, Bridgewater, New Jersey, USA

Parijat Jain Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA

“The alphabetization of chemical names and plenty of entries offer completely extensive information of aqueous solubility data expediently… suitable for the researchers in the fields of chemistry and related areas.” —Carbohydrate Polymers

“… an indispensable reference for workers in many scientific fields” —Chromatographia

“The authors have done an excellent job of compiling this information. … This is a valuable handbook for any scientific laboratory that has to dissolve organic compounds into aqueous solutions. This type of information is often difficult to find so it is nice to have so many compounds listed in a single source.” —Thomas L. Pazdernik, Ph.D., University of Kansas Medical Center

The second edition of this landmark volume continues the tradition of providing an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. It adds 2000 new solubility values, bringing the total count to over 18,000 data points for more than 4000 organic compounds. It includes data for pharmaceuticals, pollutants, nutrients, herbicides, pesticides, and agricultural, industrial, and energy-related compounds. Each compound is identified by a sequential number along with molecular formula, compound name, synonyms, molecular weight, CASR number, melting point, and boiling point if available.

“… The book is a very valuable source for specialists interested in various aspects of proteins — from physicians to biochemists, molecular biologists, geneticists, and biotechnologists. There is no doubt that this book will be very useful for medical schools and universities students and their teachers.” —G. Y. Wiederschain, Doctor of Biological Sciences, writing in Biochemistry (Moscow), Vol. 75, No. 6.

Relying upon his broad view of biotechnology, pioneering protein scientist Roger Lundblad draws from both traditional protein science and proteomics to include a great deal of material not found in electronic format. This volume explores key contributions that protein scientists can make in the development of products that are both important and commercially viable, and provides them with tools and information required for successful participation. The book explores the application of protein science for producing products as diverse as adhesives, drug delivery systems, and quality food products. The author includes chapters on the use of classical protein chemistry in food, the protein and carbohydrate chemistry of adhesives, glues, and sealants, protein chemistry and hydrogels, and the use of chemical modification to prepare protein therapeutics. While demonstrating current uses and development of biotech applications, Dr. Lundblad makes a point to separate what is truly new from that which has merely been renamed. Catalog no. 73419, 2009, 456 pp. ISBN: 978-1-4200-7341-6, $169.95 / £103.00

Catalog no. K10130, April 2010, 1620 pp. ISBN: 978-1-4398-0245-8, $399.95 / £254.00

For more information and complete contents, visit www.crcpress.com

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Biochemistry

Biomaterials & Medical Devices

Introduction to Molecular Biology, Genomics and Proteomics for Biomedical Engineers

New!

Metals for Biomedical Devices Edited by

M. Niinomi

Robert B. Northrop and Anne N. Connor

Tohoku University, Japan

University of Connecticut, Storrs, USA

"The book provides a solid introduction and a foundation that the interested student might use as a basis for further study at a more advanced level." —Books-On-Line

A unique introductory text, this book is written for engineers and scientists with little background in molecular biology, genomics, and proteomics who are working or planning to work with, living systems. The authors assume familiarity with basic calculus, physics, and linear algebra. They describe the very complex biochemical relations that permit life to exist, highlighting the specialized organic molecules in living organisms, and how they interact and react. This is a professional primer, not intended as a replacement for formal, in-depth course work, but intended to broaden the background and pique the interest of those new to this area. Catalog no. 61194, 2009, 480 pp. ISBN: 978-1-4200-6119-2, $99.95 / £46.99

Biochemistry and Molecular Biology Compendium Roger L. Lundblad Lundblad Biotechnology, Chapel Hill, North Carolina, USA

Given their widespread use in medical devices, it is vital that the fundamentals and behavior of metals are understood. This volume fills the information gap by reviewing the latest techniques in metal processing methods and the critical aspects of their behavior that might affect production and application. The text reviews the current status and selection of metals for biomedical devices before moving on to cover mechanical behavior, degradation, and testing. A final section discusses cardiovascular and orthopedic uses and the employment of next generation biomaterials. Catalog no. N10188, May 2010, 432 pp. ISBN: 978-1-4398-3107-6, $229.95 / £145.00

New!

Biointegration of Medical Implant Materials Science and Design Edited by

C.P. Sharma Sree Chitra Tirunal Institute for Medical Sciences and Technology, India

Filled with practical information not found in more database-oriented resources, this book provides a list of commonly used acronyms, with definitions, and terms used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. It includes chemicals commonly employed in biochemistry and molecular biology, complete with properties and structure drawings, as well as a detailed accounting of protease inhibitors and protease inhibitor cocktails. A list of organic name reactions used in biochemistry and a list of buffers with references to specific uses and unwanted side reactions rounds out the coverage.

Biointegration is essential for the successful performance of implanted materials within the human body. This volume provides a review of recent research into material and tissue interaction and integration. The first section discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. The second part reviews techniques in drug delivery, including inorganic nanoparticles for targeted drug delivery and alginate-based drug delivery devices. The third section covers design considerations, exploring biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use, and rapid prototyping in biomedical engineering.

Catalog no. 43471, 2007, 424 pp. ISBN: 978-1-4200-4347-1, $109.95 / £69.99

Catalog no. N10181, August 2010, 384 pp. ISBN: 978-1-4398-3064-2, $229.95 / £146.00

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Biomaterials & Medical Devices New!

Usability Testing of Medical Devices Edited by

Michael E. Wiklund, Jonathan Kendler, and Allison S. Yale Wiklund Research & Design, Inc., Concord, Massachusetts, USA

As human factors specialists who have conducted literally thousands of test sessions involving medical devices used by physicians, nurses, therapists, technicians, and patients, the authors have an informative, practical, and engaging handbook for conducting usability tests of medical devices. Recognizing that the intended readers, including marketers, engineers, and regulatory affairs specialists, are busy and disinclined to read lengthy textbooks, this book has been carefully designed to be concise and visual, allowing readers to read it all in one sitting or jump from one section to another as needed. The book provides a simple, easy to implement general understanding of usability testing and reviews key concept, highlighting the challenges of validating that protects against dangerous errors that could lead to patient injury and death. It starts with a cursory review of human factors engineering and how usability testing fits in. It continues with a review of the government regulations and industry standards that have motivated many medical device manufacturers to conduct usability tests. Then, the book covers the nitty-gritty of planning, conducting, and reporting the results of a usability test, all while trying to make the process as smooth, safe, and painless as possible. Catalog no. K10595, December 2010, c. 360 pp. ISBN: 978-1-4398-1183-2, $69.95 / ÂŁ44.99

New!

Biomaterials A Nano Approach Seeram Ramakrishna, Murugan Ramalingham, T.S. Sampath Kumar, and Winston O. Soboyejo A Self-Contained Book Illustrating Past, Present, and Future Trends in Biomaterials There are several well-known books on the market that cover biomaterials in a general way, but none provide adequate focus on the future of and potential for actual uses of emerging nanontechnology in this burgeoning field. Biomaterials: A Nano Approach is written from a multi-disciplinary point of view that integrates aspects of materials science and engineering, nanotechnology, bioengineering, and biosciences. The book fills a glaring void in the literature by providing a comprehensive discussion of biomaterials and a scientifically plausible extrapolation of likely scenarios in which nanotechnology could play a significant role. The authors introduce and examine basic concepts, processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications. Spanning from the historical development of biomaterials to cutting-edge advances in the field, the text describes how basic concepts in nanotechnology are applied to the processing of novel nanobiomaterials, including nanostructured metals and alloys. With its illustrative examples and presentation of applications, this text offers a solid framework for understanding present and future trends of biomaterials in human healthcare systems. It is an ideal companion resource for students, researchers, and industrial scientists who specialize in biomaterials and nanobiomaterials. Catalog no. 47817, June 2010, 372 pp. ISBN: 978-1-4200-4781-3, $99.95 / ÂŁ69.99

For more information and complete contents, visit www.crcpress.com

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Biomaterials & Medical Devices New!

Porous Media Applications in Biological Systems and Biotechnology

Biomaterials Fabrication and Processing Handbook Edited by

Edited by

Paul K. Chu

Kambiz Vafai

City University of Hong Kong, Kowloon

University of California, Riverside, USA

Xuanyong Liu

Presenting state-of-the-art research advancements, this volume explores innovative approaches to effectively apply existing porous media technologies to biomedical applications. In each peer-reviewed chapter, world-class scientists and engineers address significant problems and discuss exciting research in biological systems. They cover various transport processes, mechanical behavior, and material properties of biological tissues from a porous media point of view. The book also presents pertinent aspects of experimental work and numerical techniques and discusses the modeling of several phenomena, including flow changes in cerebral aneurysms, biomass growth, marine systems, and tissue homeostasis and repair.

Shanghai Institute of Ceramics, China

Catalog no. 65416, August 2010, 632 pp. ISBN: 978-1-4200-6541-1, $149.95 / £95.00

Catalog no. 7973, 2008, 720 pp. ISBN: 978-0-8493-7973-4, $157.95 / £99.00

A Laboratory Course in Biomaterials Wujing Xian University of Illinois at Urbana-Champaign, USA

A new teaching tool for instructors in biomaterials and bioengineering, this volume is a comprehensive laboratory textbook. It trains students in laboratory skills, data analysis, problem solving, and scientific writing and integrates a variety of principles that include materials science, chemistry, biochemistry, molecular and cell biology, and engineering. Providing detailed descriptions, explanations, and illustrations of experiments, the text also includes a series of questions and answers at the end of each chapter to clarify concepts. Many of the experiments presented are adapted from research papers to reflect the recent progress in biomaterials and bioengineering. Catalog no. 75829, 2009, 216 pp., Soft Cover ISBN: 978-1-4200-7582-3, $59.95 / £36.99

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Comprehensive in scope, this volume focuses on a variety of production and processing aspects of the latest biomaterials. It discusses how scaffolds are used in tissue engineering and describes common implant materials, such as hard tissue, blood contacting, and soft tissue. The book also examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bio-MEMS. With contributions from renowned international experts and extensive reference lists in each chapter, this book provides detailed, practical guidance on producing biomaterials and employing them in biomedicine.

Biomaterials Edited by

Joyce Y. Wong Boston University, Massachusetts, USA

Joseph D. Bronzino Trinity College, Hartford, Connecticut, USA

For medical devices that must be placed inside the body, the right choice of material is the most important aspect of design. To make sure such devices are safe, reliable, economical, and biologically and physiologically compatible, the modern biomedical engineer must have a broad knowledge of currently available materials and the properties that affect their in-service performance. Expanding on chapters drawn from the third edition of the best-selling Biomedical Engineering Handbook, Biomaterials surveys the wide variety of biomaterials in present use as well as materials resulting from novel micro- and nanoscale technologies.. Catalog no. 7888, 2007, 296 pp. ISBN: 978-0-8493-7888-1, $98.95 / £62.99

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Bioengineering Nanotechnology and Tissue Engineering

Tissue Engineering

The Scaffold

John P. Fisher

Edited by

Edited by

University of Maryland, College Park, USA

Cato T. Laurencin

Antonios G. Mikos

University of Virginia, Charlottesville, USA

Lakshmi S. Nair University of Connecticut, Farmington, USA

Offering a natural progression of topics, Nanotechnology and Tissue Engineering: The Scaffold provides a state-of-the-art account of groundbreaking research in this rapidly emerging area of biomedical engineering. Emphasizing the importance of scaffolds, the book details fundamental and advanced aspects of nanofabrication and examines cellular interactions at the nanoscale level. It reviews extracellular matrix structure and function and discusses various nanoscale biological surface modifications that can improve cellular responses. The editors present the most promising nanofabrication techniques, including electrospinning, lithography, and self assembly. Featuring the contributions of pioneering scientists writing about their own research, this cutting-edge volume: • Provides background information discussing the emerging importance of scaffolds in tissue engineering • Examines tissue engineering as it relates to orthopedic, cardiovascular, neural, and musculoskeletal applications • Details cell responses to a number of nanoscale features

Rice University, Houston, Texas, USA

Joseph D. Bronzino Trinity College, Hartford, Connecticut, USA

The ability to engineer biocompatible tissue is the hallmark of modern biomedical engineering, integrating all aspects of every sub-discipline in the field. Bringing in a diverse group of international contributors with backgrounds in academia, clinical medicine, and industry, this volume surveys the latest advances in this relatively young area. Divided into three sections, it discusses the fundamental concepts of tissue engineering, enabling technologies, and tissue engineering applications. It examines strategies that incorporate scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques that are being applied in regenerative medicine. Catalog no. 9026, 2007, 600 pp. ISBN: 978-0-8493-9026-5, $98.95 / £62.99

Regenerative Medicine and Biomaterials for the Repair of Connective Tissues Edited by

• Delves into microfabrication techniques in scaffold development

C. Archer and J. Ralphs

• Presents research on designer self-assembling peptide scaffolds This highly comprehensive resource also discusses clinical implications and applications, presenting exciting breakthroughs in neural, vascular, and musculoskeletal tissue engineering with nanostructures. An essential resource, for biomedical engineers working on the frontiers of tissue research, this book brings together current findings and background information on a complete range of engineering processes that have led to the development of a number of highly useful tissues.

Regenerative medicine for the repair of connective tissues is a fast moving field which generates a lot of interest. The biomaterials and biomechanics for soft tissue repair has been under-represented in the past, particularly the natural connection between cartilage, tendons, and ligaments is often not made. This book addresses the gap by exploring the natural association of cartilage, tendons, and ligaments to provide a review of the different structures, biomechanics and, providing a discussion of practical techniques and biomaterials which are being used to repair connective tissues.

Catalog no. 51822, 2008, 384 pp. ISBN: 978-1-4200-5182-7, $157.95 / £99.00

Cardiff University, UK

Catalog no. N10011, February 2010, 600 pp., ISBN: 978-1-4398-0110-9, $249.95 / £159.00

For more information and complete contents, visit www.crcpress.com

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Industry Applications Biotechnology A Comprehensive Training Guide for the Biotechnology Industry Syed Imtiaz Haider and Anika Ashtok

New!

Green Entrepreneur Handbook The Guide to Building and Growing a Green and Clean Business

Julphar Gulf Pharm. Industries, United Arab Emirates

Eric Koester

All manufacturing companies face the daunting task of designing an employee training matrix that meets the gamut of national and international regulatory standards. Answering the call for a one-stop training resource that focuses exclusively on this multi-faceted, high-tech industry, Biotechnology: A Comprehensive Training Guide for the Biotechnology Industry provides ready-to-implement training templates that save time and expense without cutting corners on critical elements. This complete, single-source reference contains 28 complete biotechnology courses and a customizable CD-ROM with hands-on training tools. The book also provides time-saving information on how to orient employees involved in writing and executing batch manufacturing and in-process control documents.

Written by a practicing business attorney with startup experience in the environmental and technology sectors, this comprehensive handbook assists entrepreneurs in tackling the wide variety of opportunities to go green. A one-stop resource for green entrepreneurs, it helps you incorporate clean technology, environmental practices, and green business approaches into your work environment. The book discusses how to sell to utilities, explores fundraising outlets for green businesses, covers government incentives, presents key startup tools aimed at green businesses, and addresses challenges of many new businesses, such as raising money and making sales. Additional resources are available on the book’s website.

Key Benefits: • Contains adaptable training text, test summaries and papers, test answers, and certificates of completion • Streamlines the training process, maximizing efficiency • Boosts the marketing edge over competitors This valuable training tool presents step-by-step guidance for optimizing research and development expenditures, avoiding marketing delays, gaining a competitive advantage, reducing product development failures, developing skilled manpower, and maintaining local and international regulatory compliance. Catalog no. 84488, 2009, 868 pp., Soft Cover ISBN: 978-1-4200-8448-1, $99.95 / £60.99

Cooley Godward Kronish LLP, Seattle, Washington, USA

Catalog no. K10895, November 2010, c. 460 pp. Soft Cover, ISBN: 978-1-4398-1729-2 $49.95 / £31.99

New!

Efficiency and Sustainability in the Energy and Chemical Industries Scientific Principles and Case Studies, Second Edition Krishnan Sankaranarayanan ExxonMobil Research and Engineering, Fairfax, Virginia, USA

Jakob de Swaan Arons and Hedzer J. van der Kooi Delft University of Technology, The Netherlands Series: Green Chemistry and Chemical Engineering

"...the text is highly readable and the authors have done an excellent job at combining a difficult subject (thermodynamics) with an area that eludes quantification due to its complexity (the environment). … It is a highly recommended read." —Polymer News, Vol. 30

Catalog no. K10757, May 2010, 393 pp. ISBN: 978-1-4398-1470-3, $149.95 / £95.00

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Industry Applications New! New!

Healthcare Biotechnology A Practical Guide Dimitris Dogramatzis Dogramatzis Pharmacy, Athens, Greece

A first of its kind to focus on the management of health-care related biotechnology, this text is a resource rich practical guide that assists all healthcare related biotech professionals in their day-to-day activities. The book is divided into six parts, following the exact journey a biomedical innovation takes through its adventurous life cycle: • • • • • •

The Healthcare Biotechnology Industry Intellectual Property Funding New Product Development Marketing Running the Business

The book contains chapters on bioeconomy, biolicensing, biofinance, biopartnering, biodrug research, biomarketing planning, biopromotion, product life cycle management, and biobusiness models, among others. Written by a well-established professional and registered pharmacist, this reference is appropriate for graduate students and industry professionals. It contains over 350 tables and figures and end-of-section problems accompany each chapter. There are also extensive references following each chapter to enhance further study. Catalog no. K12108, December 2010, c. 768 pp. ISBN: 978-1-4398-4746-6, $99.95 / £63.99

Cleaning Validation Manual A Comprehensive Guide for the Pharmaceutical and Biotechnology Industries Syed Imtiaz Haider and Erfan Syed Asif Julphar Gulf Pharm Industries, United Arab Emirates

With over 20 easy-to-use template protocols for cleaning validation of extensively used equipments, Cleaning Validation Manual: A Comprehensive Guide for the Pharmaceutical and Biotechnology Industries provides technical solutions to assist in fulfilling the training needs of finished pharmaceutical manufacturers. Drawing on the authors’ more than two decades of experience in the pharmaceutical and biotech industries, the text offers hands-on training based on current approaches and techniques. The book does not merely provide guidelines or thought processes, rather, it gives ready-to-use formulas to develop Master Plan, SOPs, and validation protocols. It includes cleaning procedures for the most commonly used equipment in various manufacturing areas and their sampling points, using a pharmaceutical manufacturing site with both sterile and non-sterile operations as the case facility. It also provides the training guidelines on a CD-ROM to enable users to amend or adopt them as necessary. Grounded in practicality, the book’s applicability and accessibility set it apart. It can be used as a guide for implementing a cleaning validation program on site without the help of external consultants, making it a resource that will not be found collecting dust on a shelf, but rather, referred to again and again. Catalog no. K11299, May 2010, 608 pp. ISBN: 978-1-4398-2660-7, $139.95 / £89.00

For more information and complete contents, visit www.crcpress.com

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Industry Applications New!

Reverse Engineering Technology of Reinvention Wego Wang University of Massachusetts, Lowell, USA

Written to advance the technology of reinvention and improve the competitiveness of commercial parts in the aftermarket, this volume discusses the proper measuring and analyses required to reproduce or repair an Original Equipment Manufacturer (OEM) part using modern reverse engineering technologies, as well as regulations that govern the practice. Offering numerous real-world examples, the book enables readers to determine if a duplicated or repaired part can meet the design functionality of the original. Going beyond industrial manufacturing, the book also looks at the use of reverse engineering in academic research, and legal and forensic analyses. Catalog no. K10314, September 2010, 357 pp. ISBN: 978-1-4398-0630-2, $139.95 / £89.00

New!

Intelligent Energy Field Manufacturing Interdisciplinary Process Innovations Edited by

Wenwu Zhang

Bioprocessing Handbook of Membrane Separations Chemical, Pharmaceutical, Food, and Biotechnological Applications Edited by

Anil K. Pabby, Syed S.H. Rizvi, and Ana Maria Sastre This critical work provides detailed information on membrane separation technologies as they have evolved over the past decades. Presenting a basic exploration of this area, the book documents the developments dealing with these technologies. It discusses chemical, pharmaceutical, and biotechnological applications of membrane processes ranging from selective separation to solvent and material recovery. This text provides comprehensive coverage of membrane separation mechanisms, transport models, membrane permeability computations, membrane types and modules, and membrane reactors. It also explores membrane applications in industrial waste management and environmental engineering. Catalog no. 9549, 2009, 1184 pp. ISBN: 978-0-8493-9549-9, $299.95 / £191.00

Process Synthesis for Fuel Ethanol Production C.A. Cardona, O.J. Sanchez, and L.F. Gutierrez

GE Global Research Center, Schenectady, New York, USA

Series: Biotechnology and Bioprocessing

An in-depth introduction to Intelligent Energy Field Manufacturing (EFM), this book explores a fresh engineering methodology that not only integrates and but goes beyond methodologies such as Design for Six Sigma, Lean Manufacturing, Concurrent Engineering, selfassembly, biometics, and more. It discusses dynamic M-PIE flows, the generalities of energy fields, logic functional materials and intelligence, the open scheme of intelligent EFM implementation, and the principles of intelligent EFM. The book takes a highly interdisciplinary approach that includes research frontiers such as micro/nano fabrication, high strain rate processes, and laser shock forming, to name just a few.

This book is a comprehensive guide to the design and analysis of the most advanced technologies for fuel ethanol production from feedstocks. It describes how process systems engineering can be applied to fuel ethanol production to achieve new levels of efficiency according to technical, economic, and environmental criteria. The authors cover liquid biofuels; various types of feedstocks, including sugars, starchy crops, lignocellulosic biomass, and microorganisms; and hydrolysis technologies, such as saccharification. They also address new technological innovations based on process integration to reduce energy consumption and the environmental issues of bioethanol production.

Catalog no. 71017, July 2010, 728 pp. ISBN: 978-1-4200-7101-6, $149.95 / £95.00

Catalog no. K10819, January 2010, 415 pp. ISBN: 978-1-4398-1597-7, $129.95 / £78.99

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Bioprocessing

The Metabolic Pathway Engineering Handbook Two-Volume Set Edited by

Christina Smolke Stanford University, California, USA Series: Metabolic Pathway Engineering Handbook

Christina Smolke is regarded as one of the most brilliant new minds in biomedical engineering. She demonstrated the power and opportunities awaiting discovery through metabolic engineering when she developed a novel way to churn out large quantities of drugs from genetically modified brewer’s yeast. And now with The Metabolic Pathway Engineering Handbook, she provides us with a reference guide to the future of biomedical engineering. Bringing together pioneering scientists from dozens of disciplines, this exciting work offers us a complete record of accomplishment in metabolic pathway engineering and lays the groundwork for those seeking to make their own contributions. Catalog no. 3923, January 2010, 1259 pp. ISBN: 978-0-8493-3923-3, $249.95 / £159.00

Also Available - Individual Volumes The Metabolic Pathway Engineering Handbook Fundamentals The Metabolic Pathway Engineering Handbook: Fundamentals provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction models, the regulation of metabolic pathways, and genome scale and multiscale modeling tools. In addition, it covers the development of appropriate hosts for metabolic engineering, including the use of Escherichia coli, Bacillus subtilis, Streptomyces, yeast, filamentous fungi, and mammalian cells using cell culture. Catalog no. K10164, January 2010, 678 pp. ISBN: 978-1-4398-0296-0, $159.95 / £99.00

The Metabolic Pathway Engineering Handbook Tools and Applications This second volume of the Metabolic Engineering Handbook delves into evolutionary tools as well as. gene expression tools for metabolic pathway engineering. It covers applications of emerging technologies including recent research genome-wide technologies, DNA and phenotypic microarrays, and proteomics. tools for experimentally determining flux through pathways. This volume also looks at emerging applications for producing fine chemicals, drugs, and alternative fuels. Catalog no. 77651, January 2010, 581 pp. ISBN: 978-1-4200-7765-0, $159.95 / £99.00

For more information and complete contents, visit www.crcpress.com

21


Math for Engineers

Practical MATLAB® for Engineers Two-Volume Set Misza Kalechman City University of New York, (CUNY) Brooklyn, USA

A comprehensive and accessible primer, this two volume tutorial immerses engineers and engineering students in the essential technical skills that will allow them to put MATLAB® to immediate use. The first volume covers concepts such as: functions, algebra, geometry, arrays, vectors, matrices, trigonometry, graphs, pre-calculus and calculus. It then delves into the Matlab language, covering syntax rules, notation, operations, computational programming. The second volume illustrates the direct connection between theory and real applications. Each chapter reviews basic concepts and then explores those concepts with a number of worked out examples. Features: • Provides a summary of basic matrix concepts, definitions, operations, and applications • Explains how to perform trigonometric, exponential, and logarithmic functions using preset definitions • Identifies the graphic commands required to obtain 2-D and 3-D plots in the Cartesian coordinate system • Differentiates between symbolic and ordinary variables in MATLAB • Demonstrates how flow control can be altered by relations, logical expressions, and branching instructions Catalog no. 47736, 2009, 900 pp., Soft Cover ISBN: 978-1-4200-4773-8, $129.95 / £86.00

What Every Engineer Should Know About Starting a High-Tech Business Venture Eric Koester Cooley Godward Kronish LLP, Seattle, Washington, USA Series: What Every Engineer Should Know, Vol. 0

Written for the engineering and technical entrepreneur desiring to launch his or her own hightech venture, this step-by-step guide offers advice on everything, starting with the initial decision to leave your employer. It contains tips on how to gain access to technologies and talent, how to anticipate problems and eliminate future hurdles, and how to guard intellectual property from the start. Discussions on the best ways to compensate employees, as well as coverage of general issues that new tech businesses face, including hiring, firing, contracts, leases, loans, and product warranties, make this a complete handbook for those who understand that a future in high-tech is the future in which to believe. Catalog no. 76973, 2009, 610 pp., Soft Cover ISBN: 978-1-4200-7697-4, $59.95 / £36.99

Applied Calculus of Variations for Engineers Louis Komzsik Siemens, Huntington Beach, California, USA

"...I firmly believe that this is a must-read book for engineers and applied mathematicians who wish to learn the important topic of calculus of variations." —Professor Duc T. Nguyen, Multidisciplinary ParallelVector Computation Center, Old Dominion University, Norfolk, Virginia, USA

Applied Calculus of Variations for Engineers addresses very important mathematical area applicable to many engineering disciplines. Its unique, application-oriented approach sets it apart from the theoretical treatises of most texts. It is aimed at enhancing the engineer’s understanding of the topic as well as aiding in the application of the concepts in a variety of engineering disciplines. Catalog no. 86626, 2009, 175 pp. ISBN: 978-1-4200-8662-1, $62.95 / £40.99

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Biotechnology A Comprehensive Training Guide for the Biotechnology Industry • Streamlines the training process • Customizable CD-ROM

Healthcare Biotechnology A Practical Guide • First of its kind to focus on management of healthcare biotechnology • Resource-rich practical guide

Cleaning Validation Manual A Comprehensive Guide for the Pharmaceutical and Biotechnology Industries • Over 20 ready-to-use template protocols • Customizable CD-ROM • Hands-on training based on modern equipment


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