Neurology

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Neurology

New and Bestselling

Books from CRC Press

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Contents Neurology ............................................................4 Neurology / Pain Management..........................25 Neuroscience ......................................................27 Neuropsychology ..............................................29 Page 5

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Psychiatry / Psychology ......................................30 Neurosurgery......................................................33

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Key Contacts Page 30

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Lance Wobus Senior Editor, Medical Lance.Wobus@taylorandfrancis.com Direct: 561-998-2584

Your Medical Marketing Team

To view more information and complete tables of contents for these and many other related books, Visit us at

www.crcpress.com

e-mail: orders@crcpress.com 1-800-634-7064 • 1-859-727-5000 +44 (0) 1235 400 524 EMM24 MC_ISSUU 7.12.13rd_gtr

Nally Dookwah-Abrams Marketing Manager for USA & Canada Email: Nally.Dookwah-Abrams@taylorandfrancis.com Direct: 561-361-6026 Matt De Bono Senior Marketing Manager for the UK, Europe, Rest of World Markets Email: matt.debono@tandf.co.uk Direct: +44 (20) 755 19391 Dominique McCann Marketing Executive for the UK, Europe, Rest of World Markets Email: dominique.mccann@tandf.co.uk Direct: +44 (20) 701 75895


CRC Press

Taylor & Francis Group

Dear Doctor: CRC Press is a global publisher of premier books in neurology and related fields. In this catalog, we are pleased to present a comprehensive collection of our new and bestselling titles written by experts from around the world. Many of these traditional format books are also available digitally, so you can choose the option that best meets your needs. Do you have an idea for a book in neurology, neuroscience, neuropsychology, or neurosurgery? We welcome proposals for new book concepts. Please contact Senior Editor Lance Wobus at Lance.Wobus@taylorandfrancis.com to discuss your project. We look forward to providing you with superior references to help you meet the desired goals of your practice in 2013 and beyond. Sincerely,

CRC Press Marketing Team, Medical

www.crcpress.com • 1-800-634-7064 • 1-859-727-5000 • +44 (0) 1235 400 524


Neurology New!

Neuroviral Infections Two Volume Set Edited by

Sunit K. Singh Centre for Cellular and Molecular Biology, Hyderabad, India

Daniel Růžek Biology Centre ASCR- Institute of Parasitology, Ceske Budejovice, Czech Republic

Viral infections of the central nervous system are often lethal. Understanding these diseases involves comprehending the interaction between the nervous system and the immune system. Available as a two-volume set, Neuroviral Infections provides in-depth information about individual viruses, the diseases they cause, and the mechanisms of spread of those diseases. Addressing both clinical and basic science aspects, these volumes cover such diseases as polio, measles, rabies, herpes, West Nile, Japanese encephalitis, and varicella-zoster. The authors also include detailed discussions of molecular pathogenesis and host-pathogen immune interaction as well as disease detection, treatment, and prevention.

Contents: General Principles and DNA Viruses Principles of Viral Infections of the Nervous System Neuroviral Infections: A Historical Perspective Neuroviral Infections and Immunity Controlling Neuroinflammation: Lessons from Rabies Virus Laboratory Diagnosis of CNS Viral Infections New Trends in Antiviral Therapy of CNS Infections Animal Models of Viral Encephalitis Neurotropic DNA Viruses and their Diseases Herpes Simplex Virus and Human CNS Infections CNS, Neurological Infections Caused by the Herpesvirus Varicella-Zoster Virus (VZV), and Models of VZV Neurotropism Epstein–Barr Virus and CNS Infections Cytomegalovirus (CMV) Infection Human Herpesvirus 6A, 6B, and 7 Encephalitis The Human Polyomavirus JC and Progressive Multifocal Leukoencephalopathy RNA Viruses and Retroviruses RNA Viruses Alphavirus Neurovirulence Neurological Chikungunya: Lessons from Recent Epidemics, Animal Models, and Other Alphavirus Family Members Arenaviruses and Neurovirology Bunyaviruses Human Coronaviruses: Respiratory Pathogens Revisited as Infectious Neuroinvasive, Neurotropic, and Neurovirulent Agents Nonpolio Enteroviruses, Polioviruses, and Human CNS Infections Neurovirulence of the West Nile Virus

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Murray Valley Encephalitis Virus Japanese Encephalitis Virus and Human CNS Infection Tick-Borne Encephalitis St. Louis Encephalitis Powassan Virus Neurological Dengue Influenza Virus and CNS Infections Human Paramyxoviruses and Infections of the Central Nervous System Rabies Virus Neurovirulence Rubella Virus Infections Retroviruses Human T-Lymphotropic Virus Human Immunodeficiency Virus Neuropathogenesis Catalog no. K13120, February 2013, 909 pp. ISBN: 978-1-4398-6852-2, $329.95 / £210.00 Also available as an eBook

These volumes are also available individually

Neuroviral Infections General Principles and DNA Viruses Catalog no. K16317, February 2013, 390 pp. ISBN: 978-1-4665-6719-1, $159.95 / £99.00 Also available as an eBook

Neuroviral Infections RNA Viruses and Retroviruses Catalog no. K16318, February 2013, 519 pp. ISBN: 978-1-4665-6720-7, $159.95 / £99.00 Also available as an eBook

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Neurology New!

Handbook of Parkinson's Disease Fifth Edition Edited by

Rajesh Pahwa and Kelly E. Lyons University of Kansas, Kansas City, USA

“… This new edition of the Handbook of Parkinson's Disease covers all new aspects of the condition and fulfils all the needs of an authoritative and recent update. The editors have put together an excellent group of authors. Each of them is a well-known specialist in their field and the chapters are scholarly and easy to read.” —Günther Deuschl, Professor of Neurology, Chairman of the Department of Neurology, Christian-AlbrechtsUniversity Kiel, Universiätsklinikum Schleswig-Holstein, Germany (from the Foreword)

Praise for the Previous Edition: “ … valuable to the neurologist or psychiatrist who treats Parkinson's patients or to anyone who enjoys the pure intellectual pleasure of watching scientific progress unfold in the understanding of Parkinson's disease.” —Journal of Neuropsychiatry and Clinical Neurosciences

“ ... covers all aspects of Parkinson's disease and is the best general text on the topic.” —Journal of Neurology, Neurosurgery & Psychiatry

Now in its fifth edition, Handbook of Parkinson's Disease is a comprehensive review of all aspects of this debilitating illness. The contributors discuss: • Early symptoms • Genetics epidemiology • Recent neuropsychological and neuroimaging techniques to enhance diagnostic accuracy • The use of animal models for diagnosis and treatment • Manifestations such as sleep dysfunction and neuropsychological aspects • The management of anxiety, depression, psychosis, and dementia • Motor and non-motor management, surgical treatments, and various non-pharmacologic approaches such as physical and occupational therapy Presenting an integrated approach to the management of Parkinsonian symptoms, the book aims to enhance patient quality of life with expert analysis of emerging treatments, including those currently being investigated. The book includes hundreds of field-specific references to current research findings

Contents: Early Iconography of Parkinson’s Disease; Christopher G. Goetz Epidemiology; Michele Rajput, Alex Rajput, Ali H. Rajput Differential Diagnosis; John Morgan, Kapil D. Sethi Pathophysiology and Clinical Assessment; Joseph Jankovic Autonomic Dysfunction and Management; Richard B. Dewey Sleep Dysfunction; Laura Nieder, K. Ray Chaudhuri Neuropsychological Aspects; Alexander I. Tröster, Steven Paul Woods Management of Anxiety and Depression; Jack Chen Management of Psychosis and Dementia; Kelvin L. Chou, Hubert H. Fernandez Neuroimaging; Ken Marek, Danna Jennings, John Seibyl Neuropathology; Dennis W. Dickson Neurophysiology and Neurocircuitry; Erwin B Montgomery, John T Gale Animal Models; Giselle Petzinger, Michael W. Jakowec Genetics; Akiko Imamura, Matthew J. Farrer, Wszolek K. Zbigniew Environmental Risk Factors; Brad A. Racette Disease Modification; David Kremens Amantadine and Anticholinergics; Khashayar Dashtipour, Joseph Chung, Allan Wu, Mark Lew Levodopa; Stewart A. Factor Dopamine Agonists; Valerie Street, Mark Stacy MAO inhibitors; Alex Rajput, Theresa A Zesiewicz, Robert Hauser COMT Inhibitors; Ronald F. Pfeiffer Investigational Pharmacological Treatments; William G. Ondo Deep Brain Stimulation; Kelly Lyons, Rajesh Pahwa Investigational Surgical Therapies; Joseph S Neimat, Parag G. Patil, Andres M. Lozano Physical and Occupational Therapy; Bas Bloem Voice, Speech and Swallowing Disorders; Shimon Sapir, Lorraine Ramig, Cynthia Fox Alternative Therapies; Jill Marjama-Lyons Catalog no. H100290, May 2013, 619 pp. ISBN: 978-1-84184-908-9, $219.95 / £135.00 Also available as an eBook

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Neurology Forthcoming!

Neuroanatomical Basis of Clinical Neurology Second Edition

Alzheimer's Disease Targets for New Clinical Diagnostic and Therapeutic Strategies Edited by

Renee D. Wegrzyn

Orhan Arslan

Adlyfe, Inc., Rockville, Maryland, USA

University of South Florida, Tampa, USA

Alan S. Rudolph

Based on the principle that the study of neurologic function and dysfunction is enhanced by a knowledge of the anatomy of the nervous system, Neuroanatomical Basis of Clinical Neurology, Second Edition bridges the gap between neuroanatomy and neurology. Discussing the peripheral and central nervous systems, the newest edition of this award-winning book includes changes and additions to the original work to better aid with the understanding of neurologic disorders through investigation of their anatomic basis.

New to the Second Edition: • New atlas and case scenarios • New discussion on radiographic neuroanatomy • Expansion on areas such as memory, mental retardation, neurotransmitters, neurogenesis, and headaches • Updated figures and illustrations • The latest information on neural circuitry and neurotransmitters

Contents: Introduction. Development of the Nervous System. Basic Elements of the Nervous System. Central Nervous System – Gross Anatomic Features And Internal Organization. Spinal Cord. Brainstem. Reticular Formation. Cerebellum. Diencephalon. Telencephalon. Neurotransmitters: Peripheral Nervous System. Autonomic Nervous System. Somatic Nervous System. Spinal Nerves. Cranial Nerves. Sensory Systems – Special Sensation. Cranial Nerve I and Olfactory System. Cranial Nerve II and Visual System. Cranial Nerve VIII – Cochlear Nerve and Auditory System. Cranial Nerve VIII – Vestibular Nerve and Vestibular System. Gustatory System. Sensory Systems – General Sensations. Cortical Sensations. NonCortical Sensations. Motor Systems: Lower Motor Neurons. Upper Motor Neurons. Extrapyramidal Motor System. Limbic System. Atlas Catalog no. K12154, January 2014, c. 650 pp. ISBN: 978-1-4398-4833-3, $79.95 / £49.99

Center for Neuroengineering, Duke University, Durham, North Carolina, USA

Recent effort has been focused on better understanding the fundamentals of Alzheimer’s disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. Alzheimer’s Disease: Targets for New Clinical, Diagnostic, and Therapeutic Strategies provides a detailed synopsis of the current state of the art of diagnostics and therapeutics and identifies emerging technologies and molecules that show promise in the management and treatment of AD.

Topics include: • The basis of AD and the role of Aß oligomers in development of disease • Existing and emerging in vitro biomarker-based methodologies for the diagnosis of AD, focusing on genetic, biochemical, and conformational strategies • In vivo imaging diagnostic approaches • Evolving diagnostic criteria, health regulatory guidelines, biomarkers in clinical trials, and available and emerging therapies • Recent progress in small-molecule diseasemodifier drug discovery efforts for AD, specifically in the areas of Aß, tau, and emerging neuroprotective/neurorepair approaches • How a case study of AD raises issues regarding clinical and pathologic criteria, risk factors, and the amyloid hypothesis • The molecular conformational factors that govern the pathogenicity of aggregating proteins, and how these factors could represent new targets for disease-modifying therapies • The latest epidemiological, pathological, biochemical, and behavioral studies that may shed some light on the risk of developing AD and similar dementias after traumatic brain injury Examining current hypotheses and suggesting possible new approaches to therapeutic clinical applications, this volume paves the way for a robust pipeline of therapeutics to combat not only AD, but a whole host of other neurodegenerative diseases. Catalog no. K11334, April 2012, 298 pp. ISBN: 978-1-4398-2708-6, $149.95 / £95.00 Also available as an eBook

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Neurology Neurological Clinical Examination

Handbook of Dystonia

A Concise Guide

Edited by

John Morris

Mark A. Stacy

St. Ives, New South Wales, Australia

Duke University Medical Center, North Carolina, USA

Joseph Jankovic

As many as 250,000 people in the United States have dystonia, making it the third most common movement disorder following essential tremor and Parkinson's disease.

Baylor College of Medicine, Houston, Texas, USA

The clinical neurological examination is a critical tool in the diagnosis of common and unusual neurological conditions encountered in the outpatient clinic and hospital ward. Presented in a logical, systematic manner, Neurological Clinical Examination and the accompanying extensive video library takes a step-bystep approach, supplying practical essentials for primary care physicians, neurologists, and trainees preparing for certifying examinations. Illustrated extensively with clear line diagrams for ready reference, the book is supplemented with more than 70 video clips that demonstrate clinical techniques and symptoms and signs of neurological conditions.

Second Edition

Authoritative and reader-friendly, Handbook of Dystonia, Second Edition provides a wide-ranging overview of the latest research and developments regarding the pathogenesis, evaluation, and management of the disease. The book offers detailed coverage of every available treatment option for dystonia and includes four categorized sections on medical management, botulinum toxin injections, phenol and neurolytic therapy, and surgical intervention.

• Covers a different condition in each chapter, selecting those aspects of the clinical examination most likely to lead to the correct diagnosis

The book reviews the genetic factors of dystonia and supplies in-depth coverage of the neuroanatomy, neurophysiology, and neuropathology of the disease. It covers secondary causes of dystonia, including drug-induced and psychogenic presentations. It also examines non-motor symptoms relating to movement disorders and analyzes innovative approaches for treatment including deep brain stimulation.

• Uses extensive clear line diagrams for ready reference

New to the Second Edition:

Features:

• Presents tables that list various causes of particular symptoms • Includes clinical pearls, tips, and management guidelines

Contents: The Wasted Hand Wrist Drop Proximal Weakness of the Arm(S) Proximal Weakness of the Leg(S) Foot Drop Gait Disturbance Facial Palsy Ptosis Abnormalities of Vision or Eye Movement Tremor Other Abnormal Involuntary Movements Speech Disturbance Higher Function Testing Assessment Of Coma Psychogenic Disorders

• Four new chapters dedicated to the discussion of individual botulinum toxins recently approved to treat dystonia: Botox, Myobloc, Disport, and Xeomin • Dystonic symptoms associated with Parkinson’s disorders • The use of Transcranial Magnetic Stimulation (TMS) as a treatment option for dystonia • Spasticity and its pathogenesis, evaluation, and treatment with toxins, other injectables and surgical therapies Summarizing what is known about the disorder, the book dramatically improves the recognition and understanding of this debilitating disease. Catalog no. H100262, May 2012, 440 pp. ISBN: 978-1-84184-851-8, $219.95 / £135.00 Also available as an eBook

Catalog no. K16991, February 2012, 134 pp., Soft Cover ISBN: 978-1-4441-4538-0, $39.95 / £24.99 Also available as an eBook

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Neurology Neurointerventional Management

Clinical Neurology

Diagnosis and Treatment, Second Edition

John W. Scadding

Fourth Edition London, UK

Nick Losseff

Edited by

National Hospital for Neurology & Neurosurgery, London, UK

Robert W. Hurst Hospital of the University of Pennsylvania, Philadelphia, USA

Robert H. Rosenwasser Thomas Jefferson University, Jefferson, Louisiana, USA

Since the publication of the first edition of this volume, interest in neurointerventional therapy has developed at an increasing pace. New device development has expanded the range of disorders amenable to neurointerventional treatment and additional research has been conducted within medical and surgical specialties on subspecialisation in neurointerventional therapy. Physicians from all specialties involved in the care of disorders of the head, neck, and central nervous system, including neurosurgery, neuroradiology, and neurology, are currently utilizing neurointerventional therapy. Neurointerventional Management: Diagnosis and Treatment, Second Edition has been re-titled from the original Interventional Neuroradiology to reflect the revolutionary changes occurring in this rapidly advancing field.

New to the Second Edition: • Diagnostic aspects of cerebrovascular disease of neurointerventional interest • Normal cerebrovascular variants • Non-shunting cerebrovascular malformations • The endovascular aspects of cerebrovascular disease in pregnancy • Neurocritical care management of endovascular patients • Anesthetic management of neurointerventional procedures • The diagnosis and management of cerebral vasculitis, dural venous sinus thrombosis, pediatric cerebrovascular disease, and uncommon and genetic cerebrovascular diseases This volume is written by a panel of today's leading experts in the field of neurointerventional therapy and edited by two neuroendovascular practitioners. The book provides background information and specific descriptions of the anatomy, techniques, disorders, procedures, and decisions commonly encountered in this field. Each chapter is illustrated with scientifically concise images, depicting pertinent neuroanatomy, imaging, neuroendovascular techniques, and related procedures.

Concise yet comprehensive, Clinical Neurology, Fourth Edition builds on the success of three previous editions in helping medical students, junior doctors, and practicing physicians acquire an improved understanding of the principles of neurology. The fourth edition has been fully revised and updated to take into account current developments in the investigation and treatment of neurological disorders. It retains a clinical focus, emphasizing the basic skills of history taking and neurological examination throughout. This edition presents expanded coverage of neurophysiology and motor neurone disease. Authored and edited by leading figures in neurology, this book is an indispensable introduction to the field of clinical neurology, for use in training and study as well as in the clinical setting.

Contents: Introduction. Symptoms of Neurological Disease. Examination of the Nervous System. Neuroimaging. Clinical Neurophysiology. Cranial Nerve Syndromes. Nerve and Root Lesions. Neurogenetics. Raised Intracranial Pressure. Headache. Craniofacial Pain. Head Injury. Epilepsy and Sleep Disorders. NeuroOncology. Spinal Disease. Peripheral Neuropathies. Motor Neuron Disease and Spinal Muscular Atrophy. Diseases of Muscle and the Neuromuscular Junction. Dementia. Movement Disorders. The Cerebellar Ataxias and Hereditary Spastic Paraplegias. Multiple Sclerosis and Related Conditions. Cerebrovascular Disease. Neurological Rehabilitation. Infections of the Central Nervous System. HIV. Neurological Manifestations of Medical Disorders. Pediatric Neurology. Respiratory Aspects of Neurological Disease. Pain in Neurological Disease. Psychiatry and Neurological Disorders Catalog no. K18266, December 2011 744 pp., Soft Cover ISBN: 978-0-340-99070-4, $115.95 / £69.99

Catalog no. H100231, April 2012, 440 pp. ISBN: 978-1-84184-806-8, $279.95 / £175.00 Also available as an eBook

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Neurology Long-Term Management of Dementia Edited by

Douglas Scharre The Ohio State University, Columbus, USA

With people living longer, dementia is now at the forefront of medical research. In answer to this changing trend, Long-Term Management of Dementia presents a standalone resource for diagnosis, treatment, and management issues for the patient suffering from this debilitating disease.

Topics covered include: • Social, legal, economic, and ethical dilemmas • Functional abilities • Driving and the dementia patient • Hygiene and nutritional concerns • Supervision models

Neurological Complications of Systemic Cancer and Antineoplastic Therapy Edited by

Herbert B. Newton The Ohio State University Medical Center, Columbus, USA

Mark G. Malkin Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin, USA

Neurological Complications of Systematic Cancer and Antineoplastic Therapy provides an in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses less common complications such as paraneoplastic disorders and neoplastic plexopathy.

• Medical complications

Highlights include:

Neurologists, psychiatrists, geriatricians, nurses, and social workers, along with family members of those suffering will find this book a valuable resource for understanding this disorder.

• The pathophysiology and molecular biology of cancer and the metastatic phenotype

Contents:

• Metabolic and nutritional disorders

Scope of Dementia Diagnosis of Mild Cognitive Impairment and Dementia Maria Pharmacotherapy of Cognition Management of Behaviors Management of Function - Instrumental Activities of Daily Living Management of Function - Basic Activities of Daily Living Medical Complications of Dementia Social Issues in Dementia Health Economics and Financial Decision Making Physician's Role Ethical Issues in Dementia Legal Issues in Dementia Caregiver Issues Local and National Resource Listing

• CNS infections

Catalog no. DK853X, November 2010, 264 pp. ISBN: 978-0-8493-3853-3, $129.95 / £81.00 Also available as an eBook

• Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses

• Neurological complications of immunotherapy and bone marrow transplants Additional chapters review problems related to each specific tumor type, such as breast, lung, and colorectal, as well as gynecological cancer, genitourinary cancer, and malignant melanoma. The book also discusses neurological complications related to treatments such as radiation and chemotherapy. Bringing clinical trial knowledge from the bench to the bedside, this volume is an essential reference for the practicing oncologist and neurologist.

Selected Contents: Biology and Pathophysiology of Nervous System Metastases. Intracranial Metastases. Epidural Metastasis and Spinal Cord Compression. Leptomeningeal Metastasis. Cranial Nerve Involvement by Metastatic Cancer. Cancer-Related Plexopathies. Cerebrovascular Complications of Malignancy. Metabolic and Nutritional Nervous System Dysfunction in Cancer Patients. ... Catalog no. DK9191, July 2010, 648 pp. ISBN: 978-0-8493-9191-0, $259.95 / £162.00 Also available as an eBook

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Neurology Autism Oxidative Stress, Inflammation, and Immune Abnormalities Edited by

100 Instructive Cases Edited by

Stephen G. Reich

Abha Chauhan, Ved Chauhan, and W. Ted Brown

University Maryland School of Medicine, Baltimore, USA

New York State Institute for Basic Research in Developmental Disabilities, Staten Island, USA

Autism: Oxidative Stress, Inflammation, and Immune Abnormalities brings together a wealth of cutting-edge evidence that is already influencing how we treat this serious condition. It looks at the role of neuropathological abnormalities, genetics, and those factors common to oxidative stress such as inflammation, immune dysfunction, aberrant cellular signaling, and gene-environment interactions. Among dozens of research topics, this volume: • Looks at interactions between genetic and environmental factors such as the maternal immune environment and prenatal/postnatal environmental stressors • Summarizes evidence for oxidative damage and inflammation in autism • Introduces a PDD behavior inventory as a tool for assessing autism • Considers autism as an aberrant adaptive response to neuroinflammation and oxidative stress • Examines the role of abnormal calcium signaling and the hypothesis that it may represent a target for novel therapeutics • Presents a hypothesis that autism arises from the dysregulation of a unified gut/brain system rather than originating in the brain alone • Proposes the utility of using a biopsychosocial method to treat autism This book shows us that autism is not only developmental but also a chronic condition based on active pathophysiology, and that it is not only behavioral but also presents somatic and systemic features. The findings in these chapters support the theory that oxidative stress plays an important role in autism. They also point to the value of conducting in-depth mechanistic studies as a way to uncover new targets for therapeutic intervention. Catalog no. 68814, October 2009, 452 pp. ISBN: 978-1-4200-6881-8, $174.95 / £118.00 Also available as an eBook

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Movement Disorders

Written in an easy-to-follow, quick reference format, Movement Disorders: 100 Instructive Cases provides a series of 100 case studies of patients with movement disorders. Radiology images, histopathology, and patient photographs are presented in full color. The book’s uniform structure of listing each disorder followed by examination, discussion, and teaching points ensures rapid assimilation of the material. A bonus DVD includes video-clips of each patient. The captions and key points provided enable the busy neurologist to quickly reference information needed in day-to-day practice.

Selected Contents: Familial Dystonia, Parkinsonism, Ataxia, and Dementia: What Is It? Primary Dystonia: A Surgical Disease? A Curable Form of Dystonia Not to Be Missed A Neurology Consultation for Parkinson’s on the Psychiatry Service Facial Twitching: What Is It and How Do You Treat It? An Uncontrollable Arm A Woman Who Can Walk But Not Stand A Child with a Severe Movement Disorder on the Psychiatry Unit Progressive Slowing and Gait Disorder Three Faces of Essential Tremor New-Onset ‘Tics’ in a Patient Treated for Gilles de la Tourette’s Syndrome How to Roll-Out the Work-Up When the Patient’s Brain has ‘Rocks’ Parkinson’s Disease, Pain, and Melanoma Ear Clicking after a Stroke Atypical Parkinsonism and Cerebellar Ataxia ‘Off’ Dystonia A Man with Parkinson’s Catching a Few ‘Z’s’ A 44-Year-Old Man with Dizziness since the Teens Weakness, Ataxia, and Myoclonus in a 68-Year-Old Woman Chorea and Action-Induced Myoclonus A Case of Seizures, Orofacial Dyskinesias, and Peripheral Neuropathy Catalog no. DU5248, November 2008, 434 pp. ISBN: 978-1-84184-524-1, $259.95 / £162.00 Also available as an eBook

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Neurology Bestseller!

Deep Brain Stimulation for Parkinson's Disease Edited by

Gordon H. Baltuch and Matthew B. Stern University of Pennsylvania, Philadelphia, USA

“This book would be a useful introduction for the novice and a good review for those more familiar with this topic.” —Colin Watts, Addenbrooke's Hospital, Cambridge, UK

Considered the largest breakthrough in the treatment of Parkinson’s disease in the past 40 years, Deep Brain Stimulation (DBS) is a pioneering procedure of neurology and functional neurosurgery, forging enormous change and growth within the field. The first comprehensive text devoted to this surgical therapy, Deep Brain Stimulation for Parkinson's Disease expertly examines all aspects of DBS from history and theory to patient evaluation, recovery, and rehabilitation.

Features: • Serves as an invaluable resource and teaching guide for patient evaluation and the selection of candidates for surgery • Describes the surgical technique for DBS placement, reviewing both frame- and framelessbased approaches • Considers the morbidity and mortality associated with the procedure and details strategies for complication avoidance • Discusses pre- and post-operative management protocols, from the intensive care unit to rehabilitative settings • Outlines medication adjustment in the post-DBS patient for enhanced patient recovery, including illustrative case examples • Reviews the effects of DBS surgery on speech, balance, autonomic function, sleep, and weight • Considers ethical and quality-of-life issues for DBS patients Edited by specialists in the top tiers of the discipline, including contributors from the pioneering Movement Disorder Group at the University of Pennsylvania, this is an indispensable companion for the entire neurological and neurosurgical community. Catalog no. DK7019, March 2007, 349 pp. ISBN: 978-0-8493-7019-9, $179.95 / £115.00 Also available as an eBook

Controversies in Neuroophthalmology A Case Based Debate Edited by

Andrew G. Lee and Reid Longmuir University of Iowa Health Center, Iowa City, USA

Jacinthe Rouleau Hôpital Notre-Dame -- CHUM, Montreal, Quebec, Canada

Neuro-ophthalmology, like in any field of medicine, has many areas where controversy exists in diagnosis and treatment. Controversies in Neuro-ophthalmology provides a comprehensive overview on the clinical presentation, diagnosis, and management of neuro-ophthalmic disorders and specifically addresses areas where there is a general lack of consensus amongst practitioners. Each chapter opens with a case to illustrate a pertinent controversy and then poses a clinical question. The issue is then discussed by world-leading experts to provide a balanced viewpoint. Designed to foster vigorous debate among colleagues, this book is essential reading for neuro-ophthalmologists, ophthalmologists, and neurologists.

Selected Contents: Should a patient with unexplained isolated optic atrophy have neuroimaging and further laboratory evaluation? Should a young patient with a new diagnosis of optic neuritis have testing and treatment for multiple sclerosis (MS)? Should a patient with optic disc edema with macular star figure (neuroretinitis) have lab testing and treatment? Should a vasculoplastic patient with non arteritic anterior ischemic optic neuropathy have any testing? What is the treatment for giant cell arteritis? Should I do a bilateral or unilateral temporal artery biopsy in suspected giant cell arteritis? Should I treat traumatic optic neuropathy? Should I do a MRI or MR venogram in every patient with pseudotumor cerebri? Should we perform carotid Doppler and cardiac echo on young patients with transient visual loss? What is the best visual field test for neuro-ophthalmology? Does visual rehabilitation therapy (e.g. Novavision) help patients with homonymous hemianopsia Catalog no. H7092, December 2009, 120 pp. ISBN: 978-1-4200-7092-7, $159.95 / £100.00 Also available as an eBook

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Neurology Cerebrospinal Fluid Disorders

Bestseller!

Management of Dementia

Edited by

Conor Mallucci

Second Edition

The Walton Centre for Neurology and Neurosurgery, Liverpool, UK

Serge Gauthier McGill Centre for Ageing Studies, Douglas Hospital, Quebec, Canada

Spyros Sgouros University of Birmingham, UK

Clive Ballard Kings College London, UK

“An excellent, helpful and practical book, and one that I greatly enjoyed. Unlike so many books I see, I believe I'll actually use this one.” —Geriatrics and Aging

“An excellent pocket reference.” —The Canadian Journal of Neurological Sciences

The second edition of Management of Dementia combines a balanced review of the latest knowledge and research in this area with practical guidance based on the authors' considerable personal experience in dementia care.

Topics include: • The diagnostic criteria of Parkinson’s disease dementia • Approaches to combat behavioural disturbances, depression, psychosis, and agitation • Suggestions for overcoming sleep disturbances • An update on the many genetic findings in Alzheimer’s disease, frontotemporal dementia, and dementia with Lewy bodies • Biological markers of Parkinson’s disease dementia • Symptomatic and disease-modifying treatments, including drugs and other potential preventive or stabilizing methods • Advice for managing the difficult later stages of dementia in long-term care • New assessment scales • Management of dementia using primary and secondary prevention • Drug treatments for patients with specific causes of dementia • Treatments based on an individual’s phenotypic and genetic features Directed at practitioners who want to practice evidence-based medicine without losing sight of the patient, this volume is designed to ensure physicians are dispensing the most appropriate pharmacology while also using other non-pharmacological treatments to their optimum effect. Concise and easy to read, the book provides readers with a full knowledge of the evolution of modern dementia care as well as the basis for understanding new developments as they occur.

Addressing the gap in the literature between pediatric medicine and geriatric medicine, Cerebrospinal Fluid Disorders examines the disorders of the cerebrospinal fluid (CSF) pathways from birth to old age.

Highlights of the book include: • Comprehensive content detailing CSF disorders and their effects on the brain and spine at all developmental stages • Key updates to recent developments that physicians can utilize in their practice • Clear organization with each section divided into background information, disease discussion, surgical aspects, controversies, and social issues—giving readers quick access to the most important information needed to properly diagnose and manage patients with CSF disorders • Multidisciplinary content written by clinicians representing a host of specialties, making the book useful for not only neurologists, but also those in related specialties involved in treating CSF disorders, including neurosurgery, pediatrics, general practice, ophthalmology, radiology, and emergency medicine • Expert patient communication tips to help practitioners deliver information to patients and their caregivers on highly sensitive issues, such as alternative treatments, quality-of-life issues, and medico-legal aspects • More than 400 illustrations to clarify content Exploring the management of the resultant effects of such disorders on both the brain and spine throughout the body’s changes in development, the book is written by more than 50 global experts in neurology and related disciplines. Their combined wisdom offers the most effective diagnostic and management guidelines for treating patients with CSF disorders. Catalog no. DK3435, December 2009, 640 pp. ISBN: 978-0-8247-2833-5, $299.95 / £189.00 Also available as an eBook

Catalog no. Y007135, August 2009, 176 pp., Soft Cover ISBN: 978-1-84184-667-5, $159.95 / £100.00 Also available as an eBook

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Neurology Bestseller!

Thrombus and Stroke Edited by

Ajay K. Wakhloo, Matthew J. Gounis, Baruch B. Lieber, Robert A. Mericle, and Italo Linfante Providing a clear foundation as to what a clot is, how it forms, and the most recent approaches to treatment, Thrombus and Stroke is an all-inclusive resource covering: • The fundamental science of clot formation and the pharmacokinetics of thrombolysis • The clinical impact of thrombus as it pertains to stroke and the most recent clinical and minimally invasive approaches to this disorder • Current pharmacological interventions and the latest findings on neurovascular disease • Clinical management of stroke • Thrombogenicity of vascular implants • In vivo stroke modeling • Methods to assess the efficacy of anticoagulation therapy From the latest imaging techniques to endovascular treatments, this comprehensive, advanced volume provides critical data needed for diagnosis and treatment. The valuable information will assist physicians in the prevention of future strokes and complications and will aid in improving patient outcomes throughout treatment.

Contents: Thrombus Formation Blood Flow and Thrombus Formation In vivo Experimental Models of Focal Ischemic Stroke Assessment and Management of Vascular Implant Thrombogenicity Stroke IMaging (CT, MR, SPECT, PET) Pharmacology and Clot: Immediate and Chronic Interventions Acute Ischemic Stroke: Endovascular Revascularization and Reperfusion The Future of Neuroprotection Acute Ischemic Stroke: Paradigm for Treatment Catalog no. DK965X, June 2008, 232 pp. ISBN: 978-0-8493-4196-0, $119.95 / £75.00 Also available as an eBook

Acute Brain and Spinal Cord Injury Evolving Paradigms and Management Edited by

Anish Bhardwaj and Jeffrey R. Kirsch Oregon Health & Science University, Portland, USA

“ … the editors have built a vital ‘go-to’ text which serves as a one-stop reference summarizing the latest advancements in the field. … Recommended to all neurologists and cerebrovascular surgeons for use in the direct treatment of patients. Further recommended to all health science libraries as a general reference with long-term research value. Instructors should note that this title would also prove useful as a classroom teaching text in advanced courses designed to prepare the student for a career in neurological medicine.” —John Aiello, The Electric Review

The clinical management of patients with acute brain and spinal cord injury has evolved significantly with the advent of new diagnostic and therapeutic modalities. Acute Brain and Spinal Cord Injury presents the latest medical science and highlights controversies in the clinical management of patients with acute brain and spinal cord injuries. Divided into five sections—traumatic brain injury, ischemic stroke, intracerebral and subarachnoid hemorrhage, and spinal cord injury—this text: • Delineates diagnostic and monitoring tools, pharmacotherapies, and interventional and surgical treatments • Examines and explores recently published laboratory trials and research • Incorporates over 50 diagrams and figures for concise communication of scientific information This standalone reference is a powerful tool in helping today’s neurologists and neurosurgeons keep abreast of current advances in brain and spinal cord injury.

Selected Contents: Decompressive Hemicraniectomy in the Management of Severe Traumatic Brain Injury. Cerebroprotective Strategies in Bedside Management of TBI. Diffuse Axonal Injury and Dysautonomia. Neuromonitoring in Traumatic Brain Injury: Evolving Paradigms. Hypothermia and Pharmacologic Coma in the Treatment of Traumatic Brain Injury. Pediatric Traumatic Brain Injury. Decompressive Hemicraniectomy for Large Hemispheric Infarctions. Anticoagulation in Ischemic Stroke. Catalog no. H4794, March 2008, 464 pp. ISBN: 978-1-4200-4794-3, $179.95 / £115.00 Also available as an eBook

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Neurology Endovascular Techniques in the Management of Cerebrovascular Disease Edited by

Thomas J. Masaryk, Peter Rasmussen, Henry Woo, and David Fiorella Cleveland Clinic Foundation, Ohio, USA

Direct from the Cleveland Clinic Foundation, Endovascular Techniques in the Management of Cerebrovascular Disease is intended for neurologists, neurosurgery fellows-in training, and practicing clinicians with an interest in endovascular procedures. This essential volume: • Reviews equipment, devices, and therapeutic agents such as anti-coagulants and thrombolytics • Describes the clinical management of ischemic cerebrovascular disease, including thrombectomy and stenting

Mayo Clinic Essential Neurology Andrea C. Adams Mayo Clinic, Rochester, Minnesota, USA

The field of neurology continues to evolve rapidly. Treatment options are increasing in number and improving in efficacy and diagnostic imaging allows us to see more detail in a noninvasive manner. There are few areas of the field not affected by the tools of molecular genetics. Despite all this, it is the clinical interaction with the patient—the history and examination—that continues to be the underpinning of the specialty. Mayo Clinic Essential Neurology covers the full scope of neurology by combining a focused need-toknow format with core basics along with diagnosis and treatment guidelines. More than 75 color illustrations and numerous therapeutic tables help residents and clinicians diagnose, treat, and manage the most commonly encountered neurologic problems.

• Examines hemorrhagic CVD and discusses aneurysms, subarachnoid hemorrhage, and vascular malformations

Topics include:

• Explains cutting-edge techniques related to occlusive cerebrovascular disease, arteriovenous malformation, and other extra- and intracranial cerebrovascular diseases

• Diagnostic tests • Headache • Spine and limb pain • Dizziness

Contents:

• Sensory loss and paresthesias

Technical Considerations Imaging System Review Diagnostic Devices/ Manuevers Therapuetic Devices Ischemic Cerebrovascular Disease Acute Occlusive Stroke Thrombolysis Mechanical Thrombectomy Angioplasty/Stenting Hemorrhagic Cerebrovascular Disease Aneurysm/ Subarachnoid Hemorrhage Venous Disease Catalog no. DU6074, September 2008, 216 pp. ISBN: 978-1-84184-607-1, $159.95 / £100.00 Also available as an eBook

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• The neurologic examination

• Weakness • Cognitive loss • Spells • Pain • Cerebrovascular disease • Movement disorders • Immune and infectious diseases • Neuro-oncology With comprehensive coverage suitable for the practicing physician, the clear format also makes it the perfect introduction for medical students. This full-color guide to the essentials of neurology provides one of the most focused presentations in the field today. Catalog no. H7973, December 2008 400 pp., Soft Cover ISBN: 978-1-4200-7973-9, $79.95 / £50.00 Also available as an eBook

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Neurology Bestseller!

Mayo Clinic Medical Neurosciences Organized by Neurologic Systems and Levels, Fifth Edition

Functional Neuroimaging A Clinical Approach Edited by

Andrei I. Holodny Memorial Sloan-Kettering Cancer Center, New York, USA

Incorporating a strong application to real clinical problems, this fifth edition of Mayo Clinic Medical Neurosciences provides one of the most contemporary and succinct teaching approaches to the current status of basic neuroscience knowledge.

The first text designed specifically with clinical practitioners in mind, Functional Neuroimaging demonstrates the clinical application and utilization of functional neuroradiology for early diagnosis, neurological decision-making, and assessing response to cancer therapy. Edited by the Founding President of American Society of Functional Neuroradiology, this guide expertly describes the incorporation of this technology into clinical practice and showcases high-quality color images depicting the function and mechanisms of the brain.

Highlights of the Fifth Edition:

Features:

• A succinct format provides readers a quicker way of learning the most important elements of medical neuroscience

• Helps clinicians incorporate functional neuroradiology into their practice

Edited by

Eduardo E. Benarroch, Jasper R. Daube, Kelly D. Flemming, and Barbara F. Westmoreland Mayo Clinic, Rochester, Minnesota, USA

• A focused application to clinical medicine reinforces neuroscience concepts and improves retention • A strong emphasis on critical developments in neuroscience, including neurochemistry and genetics, ensures readers are up to date on essential advances • Skillfully rendered full-color illustrations detail the core focus of anatomy and systems throughout the text Setting a standard for excellence in introductory medical neuroscience education, this book presents unique skillbuilding methods that facilitate learning through problem solving, while keeping readers engaged and focused.

Selected Contents: Survey of the Neurosciences. Integrated Neuroscience for the Clinician. Development of the Nervous System (Neuroembryology). Diagnosis of Neurologic Disorders: Anatomical Localization. Diagnosis of Neurologic Disorders: Neurocytology and the Pathologic Reactions of the Nervous System. Diagnosis of Neurologic Disorders: Transient Disorders and Neurophysiology. Synaptic Transmission and Neurochemical Systems. Longitudinal Systems. The Sensory System. The Motor System. The Internal Regulation System. The Consciousness System. Cerebrospinal Fluid: Ventricular System. Catalog no. H4516, February 2008, 824 pp. ISBN: 978-1-4200-4516-1, $79.95 / £50.00 Also available as an eBook

• Shows new advancements in functional brain imaging to benefit the diagnosis, management, and treatment of patients • Depicts current methods for imaging the central nervous system, as well as cutting-edge approaches for the imaging of brain function • Contains 320 intricate, full-color figures comprising the anatomy and function of the brain Neuroradiologists, radiologists, neurologists, neurosurgeons, and clinical psychologists will find this an essential guide to enhance the quality of their practice.

Selected Contents: Blood Oxygen Level Dependant Functional MRI (Bold FMRI). A Historical Perspective on Functional Neuroimaging. Physical Principles of Bold fMRI – What Is Important for the Clinician. Preparing the Patient for the fMRI Study. Optimization of Paradigm Selection and Delivery. Methods of Analysis. Fact or Artifact? Language. Vision, Memory and Higher Cortical Function. Cortical Plasticity. Functional Image Guided Neurosurgery. Developmental Disorder. Neurodegenerative Disorders. Diffusion Imaging. Diffusion Imaging and Tensor Physics for the Clinician. Diffusion Weighted Imaging in Stroke. Diffusion Imaging in Brain Tumors and Treatment Response. DTI of Developmental and Pediatric Disorders. DTI of Neurodegenerative Disorders. Catalog no. DK7056, June 2008, 352 pp. ISBN: 978-0-8493-7056-4, $239.95 / £150.00

For more information and complete contents, visit www.crcpress.com

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Neurology Greenfield's Neuropathology Image DVD

Textbook of the Neurogenic Bladder

Eighth Edition

Edited by

Seth Love

Jacques Corcos

Frenchay Hospital, Bristol, UK

Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada

David Louis Massachusetts General Hospital, Boston, USA

David W Ellison St. Jude Children's Research Hospital, Memphis, Tennessee, USA

“ … builds well on the outstanding strength of the previous editions. It will maintain its place as a key textbook of neuropathology. … should be on the shelves of all diagnostic histopathology departments and clinical and experimental neuropathologists.” —Dr.Thomas S. Jacques, The Bulletin of the Royal College of Pathologists

This eighth edition of the world's leading neuropathology reference continues to provide the definitive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. Greenfield's Neuropathology Image DVD: • Presents the work of expert contributors guided by a highly regarded editorial team to provide a truly global perspective • Covers authoritatively and comprehensively all the pathological findings in neurological disease along with their biological basis and clinical manifestations • Places in context the science underpinning the molecular and cellular processes described, assisting non-specialists in their understanding of the material • Uses a convenient format, with key information placed in boxes or tables for ease of reference • Includes more than 2,700 high-quality photographs and explanatory line diagrams— the majority in full colour Care has been taken to ensure that the information is presented in a way that is accessible to readers working within a range of disciplines in the clinical neurosciences, and that also places the neuropathological findings within the context of a broader diagnostic process. Catalog no. K17449, March 2008, DVD ISBN: 978-0-340-90683-5, $279.95 / £170.00 Also available as an eBook

Eric Schick Maisonneuve-Rosemont Hospital, Montreal, Quebec, Canada

“ … This is an outstanding reference text for the urologist who deals with neurogenic patients often or, possibly more importantly, the urologist who only sees such patients rarely. … the urologist can find extremely detailed information on the anatomy and physiology and pathophysiology of the condition of interest.” — BMA Medical Book Competition, First Prize, Urology Category

“I am convinced that this book should become standard reading for everyone involved in the care of neurogenic bladder patients … I cannot think of a single item in the overall topic that has not been carefully treated in depth.” —Tage Hald, Former Chairman of the ICS Standard Committee

All patients with vesico-urethral dysfunction, regardless of the nature of the neurological process causing it, are investigated with the same diagnostic tools. Textbook of the Neurogenic Bladder provides physicians—whether qualified or in training—with excellent instruction for conducting thorough, efficient, and beneficial examinations of both adults and children using a variety of instruments and tests.

Features: • Clarifies the differing states of neurogenic bladder dysfunction • Describes the pathophysiology of neurogenic bladder dysfunction and the ways it alters vesico-urethral function • Provides an overview of quality of life instruments that help determine the main outcome of interventions • Covers imaging, electrophysiology, and extensive urodynamic studies in adults and children • Discusses new non-surgical options and new ways to administer traditional treatments • Includes a full chapter on a new classification system by its developer, Professor Anders Mattiasson Catalog no. DU3163, September 2008, 928 pp. ISBN: 978-0-415-42316-8, $589.00 / £375.00 Also available as an eBook

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Neurology Restoration of Function in Upper Limb Paralyses and Muscular Defects Edited by

Raoul Tubiana, Alain Gilbert, Caroline Leclercq, and René Malek Institut de la Main, Paris, France

Restoration of Functions in Upper Limb Paralyses and Muscular Defects provides the necessary information for the surgical management of muscular defects and neurobiological disorders of the upper extremity and details the restoration of essential functions in this area.

This text examines: • Upper extremity paralysis and muscular deficits • Free muscle transfer • Obstetrical paralyses: primary surgery • Volkmann syndrome • The tetraplegic upper limb • Physiology of nerve regeneration • Electrodiagnosis studies • Pathological mechanics Drawing on extensive practical clinical experience, the contributors to this volume present practitioners working with these afflicted patients with an authoritative, insightful resource to find solutions for a range of paralysis challenges and further enhance their practice.

Selected Contents: Introduction. Upper Extremity Paralysis and Muscular Deficits. Surgical Classification of Upper Limb Paralyses. Examination of Upper Limb Paralyses. Electrodiagnosis in Upper Extremity Paralysis. Basic Notions of Biomechanical Physics. Biomechanical Research on Muscle--Tendon Transfers. Free Functioning Muscle Transfer. Normal and Pathological Mechanics of the Shoulder. Paralytic Disorders of the Shoulder Girdle. Normal and Pathological Mechanics of the Elbow and Pronosupination. Paralyses of the Elbow: Flexion and Pronosupination. Normal and Pathological Mechanics of the Wrist. Restoration of Extension of Wrist and Digits. Normal and Pathological Mechanics of the Digits. Restoration of Flexion of the Fingers. Normal and Pathological Biomechanics of the Thumb. Restoration of Thumb Opposition. ... Catalog no. DU3814, December 2008, 480 pp. ISBN: 978-1-84184-381-0, $319.95 / £200.00 Also available as an eBook

Bestseller!

Traumatic Brain Injury Methods for Clinical and Forensic Neuropsychiatric Assessment, Second Edition Robert P. Granacher, Jr. University of Kentucky, Lexington, USA

“With expanded discussions of brain-injury malingering and family dynamics, this revised and updated bestselling text gives an overview of state-of-theart techniques and discusses new pharmacological treatments, acquired psychopathology, and test instruments for assessing behavior.” —Sirreadalot.org

Since the original publication of Traumatic Brain Injury: Methods for Clinical & Forensic Neuropsychiatric Assessment, enhanced clinical findings concerning traumatic brain injury have improved our ability to evaluate and treat individuals with TBI. Unfortunately, the dramatic rise in the occurrence of brain injuries over the same time period demands better proficiency in evaluation and treatment. In an effort to optimize forensic and medical examinations of the victims of traumatic brain injury, this volume provides additional research, practical guidelines, and the latest advances and applications in structural and functional imaging assessment techniques. With case studies and images from functional MRI, PET scans, and MR spectroscopy, the second edition places more emphasis on mild traumatic brain injury, including expanded information on sports injuries in children and athletes. It discusses the neuroanatomical and neuroimaging bases of cognitive domains of the brain and includes findings on the epidemiology and pathophysiology of brain injury, as well as acquired psychopathology following injury. It also investigates the physical effects and psychiatric ramifications of blast over-pressure as seen in combat veterans and civilians in Kosovo, Lebanon, and Iraq. Additional chapters emphasize forensic evaluation with discussions on the detection of brain-injury malingering, determination of impairment, methods of neurobehavioral analysis, and the presentation of evidence at trial. Providing practical guidelines for using state-of-the-art, brain-based assessment techniques, this volume establishes a neuropsychiatric schema for the evaluation of traumatic brain injury and provides tools for designing a treatment plan. The methods in this book can be used to evaluate and treat any neuropsychiatric disorder with the addition of appropriate laboratory studies and pathology-specific treatment. Catalog no. 8138, December 2007, 584 pp. ISBN: 978-0-8493-8138-6, $179.95 / £115.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Neurology Clinical Diagnosis and Management of Dystonia Edited by

Thomas T. Warner Royal Free Hospital, London, UK

Susan B. Bressman Beth Israel Medical Center, New York, USA

One hundred years have passed since the first clinical descriptions of dystonia cases appeared in the literature. In the ensuing century, the study of this protean movement disorder has undergone a turbulent evolution, with dramatic shifts in the views regarding its causation and phenomenology. Considered for a period of time as a psychological or psychiatric condition, the dystonias are now recognized, in the majority of cases, as an organic neurological disorder. The clinical signs and symptoms manifested in patients with various dystonic disorders are extremely varied, so while it is one of the most common movement disorders, it is perhaps the most misunderstood and least clinically recognized. With chapters contributed by experts from both sides of the Atlantic, Clinical Diagnosis and Management of Dystonia provides a comprehensive review of the pathogenesis of dystonia, an overview of the classification of the various dystonic disorders, and a summary of the latest developments in treatment, including emerging pharmacological therapies and the use of botulinum toxin.

Encephalitis Diagnosis and Treatment Edited by

John Halperin Overlook Hospital, Summit, New Jersey, USA

Inflammation of the brain, usually brought on by a viral infection, encephalitis currently poses a grave threat to patients around the world. With the migration of West Nile virus into North America, there is a greater awareness and corresponding need to understand, diagnose, and manage this illness. In Encephalitis: Diagnosis and Treatment, experts discuss advances in diagnostic tools, as well as therapeutic approaches that allow clinicians to better recognize and treat afflicted patients. Individual chapters address the principal infectious and non-infectious causes of brain inflammation, including paraneoplastic encephalitides—an apparent autoimmune process in patients with malignancies— as well as acute disseminated encephalomyelitis, a post-infectious disorder. The book addresses etiology, epidemiology, and specific issues in diagnosis, pathology, and treatment, including various laboratory methodologies, pathologic changes seen in the different disorders, and diagnosis and management of the seizures that occur quite frequently in these disorders. With contributions from a group of international experts, the book provides a perspective on this disorder that is both broad and in-depth.

Contents:

Contents:

Diagnosis of Dystonia. Epidemiology of Dystonia. Overview of Genetics of Dystonia. Pathophysiology of Dystonia. Functional Imaging in Primary Dystonia. DYT1 dystonia. Other Primary Generalised Dystonias. Cervical Dystonia. Cranial Dystonia. Writer's Cramp, Limb Dystonia, and Other Task Specific Dystonias. Laryngeal Dystonia. Dystonia-plus Syndromes. Secondary Heredodegenerative Conditions. Druginduced and Tardive Dystonia. Paroxysmal Dyskinesias. Psychogenic Dystonia. Drug Therapy of Torsion Dystonia. Botulinum Toxin. Surgery for Dystonia. Role of the Physiotherapist. Role of the Specialist Dystonia Nurse. Dystonia and Quality of Life. Dystonia Rating Scales

Clinical Approach in Encephalitis. Encephalitis, Encephalopathy, and Epilepsy. Neuropathology of Encephalitis. Molecular and Serologic Methods for Diagnosis of Encephalitis. Critical Care Management of Encephalitis. Viral Encephalitis—Background, Arboviruses, and Enteroviruses. West Nile Virus. TickBorne Encephalitis. Herpesvirus Encephalitis. Rabies. HIV-Associated Brain Disease. Spirochetal Infections of the Nervous System. Encephalitis Due to Parasites. Neurobrucellosis. Listeria Infections and the Central Nervous System. Tuberculosis of the Central Nervous System. Acute Disseminated Encephalomyelitis. Paraneoplastic and Related Forms of Encephalitis. Index

Catalog no. DU1816, December 2007, 434 pp. ISBN: 978-1-84184-317-9, $129.95 / £80.00 Also available as an eBook

Catalog no. DK0314, November 2007, 360 pp. ISBN: 978-0-8493-4031-4, $179.95 / £115.00 Also available as an eBook

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Neurology Bestseller!

Interventional Neuroradiology

Handbook of Neurofeedback

Edited by

Dynamics and Clinical Applications

Robert W. Hurst

Edited by

Hospital of the University of Pennsylvania, Philadelphia, USA

James R. Evans Moore, Oklahoma, USA

Robert H. Rosenwasser

Handbook of Neurofeedback is a comprehensive introduction to this rapidly growing field, offering practical information on the history of neurofeedback, theoretical concerns, and applications for a variety of disorders encountered by clinicians. Disorders covered include ADHD, depression, autism, aging, and traumatic brain injury. Using case studies and a minimum of technical language, the field’s pioneers and most experienced practitioners discuss emerging topics, general and specific treatment procedures, training approaches, and theories on the efficacy of neurofeedback.

Thomas Jefferson University, Philadelphia, Pennsylvania, USA

Through the combination of the latest imaging modalities and microdevice delivery, interventional neuroradiologic techniques are currently revolutionizing the therapy for many of the most common neurological and neurosurgical disorders. Crossing the boundaries of classically delineated medical and surgical specialties including neurosurgery, neuroradiology, and neurology, interventional neuroradiology uses advanced neuroimaging combined with endovascular techniques to guide catheters and devices through blood vessels. These procedures can treat diseases involving structures of the head, neck, and central nervous system. These advances now provide noninvasive treatment for many disorders that were previously treated only with open surgical techniques, and make treatments possible for many patients—who until recently would have had no acceptable therapeutic options. Interventional Neuroradiology discusses CT, MRI, and ultrasonographic evaluation of cerebrovascular disease, focusing on current neuroimaging evaluation of disorders. It emphasizes the integration of current neuroimaging information into decision-making and performance practices for neuroendovascular procedures. The book describes clinical techniques and includes the most current technical modifications for the varying devices in use today. Filled with scientifically concise illustrations, the text depicts pertinent neuroanatomy, imaging, and neuroendovascular techniques. Written by a panel of today's leading experts in the field of interventional neuroradiology, this volume demonstrates the potential of these lifesaving techniques.

Selected Contents: Vascular Anatomy of the Head, Neck, and Skull Base. Applied Neurovascular Anatomy of the Brain and Skull. Vascular Anatomy of the Spine and Spinal Cord. Intracranial Collateral Routes and Anastomoses in Interventional Neuroradiology. CT Imaging and Physiologic Techniques in Interventional Neuroradiology. MR Angiography: Principles and Applications in Interventional Neuroradiology. Catalog no. DK9562, October 2007, 440 pp. ISBN: 978-0-8493-9562-8, $279.95 / £178.00 Also available as an eBook

The book includes comments on the future of the field from an inventor of neurofeedback equipment and a discussion on the theory of why neurofeedback training results in the alleviation of symptoms in a wide range of disorders. The contributors review of procedures and a look at emerging approaches, including coherence/phase training, inter-hemispheric training, and the combination of neurofeedback and computerized cognitive training.

Topics discussed include: • • • • • • • • • • • • • •

Implications of network models for neurofeedback The transition from structural to functional models Client and therapist variables Treatment-specific variables Tomographic neurofeedback Applying audio-visual entrainment to neurofeedback Common patterns of coherence deviation EEG patterns and the elderly Nutrition and cognitive health ADHD definitions and treatment Attention disorders Autism disorders The neurobiology of depression QEEG-guided neurofeedback

This book is an essential professional resource for anyone practicing, or interested in practicing neurofeedback, including neurotherapists, neuropsychologists, professional counselors, neurologists, neuroscientists, clinical psychologists, and psychiatrists. Catalog no. HW14961, August 2007 278 pp., Soft Cover ISBN: 978-0-7890-3360-4, $79.95 / £50.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

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Neurology Atlas of Alzheimer's Disease

Head and Neck Manifestations of Systemic Disease

Howard Feldman

Edited by

University of British Columbia, Vancouver, Canada

Jeffrey P. Harris

Bestseller!

“The scope of the Atlas of Alzheimer’s Disease is broad […] We recommend it to all clinicians—and clinicians in training—who are involved in the diagnosis and care of patients with AD, because it will increase their insight into this already widespread disorder.” —Wiesje M. van der Flier and Philip Scheltens, The Lancet Neurology

The last 20 years have brought unprecedented new knowledge to our understanding of Alzheimer's disease (AD) and for the first time, approved symptomatic treatments. Authored by one of the world's leading authorities on the management of AD and related dementias, this highly illustrated Atlas of Alzheimer’s Disease describes the colorful history of the illness, its neuropathological basis from structural brain imaging and post-mortem studies, and its devastating effects on perception, cognition, communication, and social behavior. In addition to an accurate and detailed historical perspective, the book provides a state-of-the-art review of current working hypotheses, diagnostic approaches, and treatments of AD. Many tables and illustrations help readers comprehend the scientific information provided, and the book places great emphasis on the increasingly identifiable risk factors for development of the disease, with a view towards prevention.

Contents: Historical Aspects Epidemiology (World View) Clinical Diagnosis Neuropathology Neuroimaging Prevention Treatment Future Catalog no. DU0451, July 2007, 166 pp. ISBN: 978-0-415-39045-3, $159.95 / £100.00 Also available as an eBook

University of California, San Diego, USA

Michael H. Weisman Cedars Sinai Medical Center, Los Angeles, California, USA

“This book provides a great wealth of the most current information for today's readers and will serve as a respected resource for decades to come …. a treasure trove of knowledge.” —James B. Snow, Jr., Professor Emeritus, University of Pennsylvania School of Medicine, and Former Director, National Institute on Deafness and Other Communication Disorders, National Institutes of Health (from the Foreword)

Written by distinguished scientist-clinicians who have made pioneering contributions in the fields of otolaryngology, rheumatology, and immunology, Head and Neck Manifestations of Systemic Disease presents critical information on a multitude of maladies that have manifestations in the head and neck. The book relates commonly encountered head and neck symptoms and signs to an array of diseases and disorders that should be considered in the differential diagnosis. Offering a hands-on approach, this volume addresses specific disease classifications and commonly encountered signs and symptoms in the head and neck region. It offers a clinical approach to disease diagnosis by analyzing the possible causes of a patient’s symptoms. The contributors present evidence-based therapeutic options for a variety of conditions, from infections and rheumatologic conditions to hematologic and neoplastic disease. Organized by disease type for easy reference, the book offers a variety of color photographs, providing a unique reference for clinicians who manage diseases with symptoms in this region.

Contents: Systemic Disorders with Head and Neck Manifestations Rheumatic Diseases Other Systemic Disorders Differential Diagnosis and Treatment Of Clinical Resentations in the Head and Neck Catalog no. DK405X, July 2007, 608 pp. ISBN: 978-0-8493-4050-5, $259.95 / £165.00 Also available as an eBook

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Neurology Clinical Manual of Trigeminal Neuralgia

Bestseller!

M. Alan Stiles, Somsak Mitrirattanakul, and James Evans

An Illustrated Study Guide

Jefferson Headache Center, Philadelphia, Pennsylvania, USA

Research into pain has grown exponentially over the past few years, and our understanding of mechanism and pharmacology has also developed. Trigeminal neuralgia often goes unrecognized or is mistaken for other causes of facial pain, and while the cause often cannot be determined, it can be associated with multiple sclerosis, herpes zoster, and various tumors. With newer medications and advances in surgical techniques, patients with trigeminal neuralgia now have more treatment options than ever before, and it is important that clinicians are aware of these in order to improve their care. Clinical Manual of Trigeminal Neuralgia familiarizes clinicians with the diagnosis of trigeminal neuralgia and describe the range of current treatments available. Key areas covered include diagnostic procedures, medical and surgical management—including gamma knife surgery—and guidelines on non-pharmacologic therapy.

Neurology Board Review Edited by

Nima Mowzoon Private Practice, Albany, New York, USA

Kelly D. Flemming Mayo Clinic, Rochester, Minnesota, USA

Preparing readers for the written portion of the Neurology Board examination and the Residency InService Training Examination (RITE) of the American Academy of Neurology, Neurology Board Review: An Illustrated Study Guide provides a comprehensive review of the most critical topics in neurology. With the abundance of neuropathology and neuroimaging figures and neuroanatomy and neurophysiology illustrations, readers will not need to refer to multiple sources to prepare for these exams.

Written by a team from one of the leading centers for the study of neurologic head and neck pain, this book is a highly practical reference for the clinician dealing with common and difficult-to-manage problems in this area.

The book is designed to help readers identify and diagnose multiple disorders covered in the exam or reviewed in residency. Numerous tables and highlighted boxes facilitate the comprehension of difficult but critical information. More than 250 neuroradiology figures, including MRI, CT, and functional images help readers advance their diagnostic skills. The book also contains a comprehensive review of basic principles of psychiatric disease and related pharmacology as well as a discussion of neuroanatomy, the basics of neuroscience, and neuroanatomic pathways.

Contents:

Contents:

Evaluation of the Facial Pain Patient. History of Illness. Physical Examination. Diagnostic Testing. Trigeminal Neuralgia-Differential Diagnosis. Diagnosis of Trigeminal Neuralgia. Differential Diagnosis of Facial Pain Disorders. The Clinical Approach to Trigeminal Neuralgia Treatment. Pathogenesis of Trigeminal Neuralgia. Medical Approach to Managing Trigeminal Neuralgia. Surgical Approach to Managing Trigeminal Neuralgia. Medical Management of Trigeminal Neuralgia. Medications for Preventing Trigeminal Neuralgia. Medications for the Acute Trigeminal Neuralgia Attack. Surgical Management of Trigeminal Neuralgia. Injections and Rhizotomies. Decompression of the Trigeminal Nerve (The Janetta Procedure). Gamma Knife Surgery. Treatment of Refractory Cases of Trigeminal Neuralgia. Medication Management. Surgical Options. Nonpharmacologic Therapy. Recommended Reading

Embryology and Developmental Disorders of the Nervous System. Basic Principles of Neuroscience and Neurogenetics. Neuro-Ophthalmology. Disorders of the Cranial Nerves. Clinical Neurophysiology. Basic Principles of Psychiatry. Behavioral Neurology. Movement Disorders. The Cerebellum and Cerebellar Disorders. Principles of Critical Care Neurology. Cerebrovascular Disease. Epilepsy. Neurocutaneous Syndromes. Inflammatory and Demyelinating Disorders of the Central Nervous System. Neurology of Infectious Diseases. Neoplasms of the Nervous System and Related Topics. Toxic and Metabolic Disorders of the Nervous System. Headache. Neurology of Sleep Disorders. Disorders of the Spinal Cord and Anterior Horn Cells. Disorders of the Peripheral Nervous System. Disorders of the Autonomic Nervous System. Disorders of Neuromuscular Transmission. Disorders of Muscle. Inborn Errors of Metabolism

Catalog no. DU2534, May 2007, 136 pp. ISBN: 978-1-84214-253-0, $99.95 / £60.00 Also available as an eBook

Catalog no. MY3791, April 2007, 1024 pp. ISBN: 978-0-8493-3791-8, $129.95 / £81.00 Also available as an eBook

For more information and complete contents, visit www.crcpress.com

21


Neurology Parkinson's Disease

Bestseller!

Multiple Sclerosis Therapeutics

Genetics and Pathogenesis Edited by

Third Edition

Ted M. Dawson

Edited by

Johns Hopkins University, Baltimore, Maryland, USA

An authoritative collection of recent breakthroughs in Parkinson's disease (PD) research, Parkinson’s Disease: Genetics and Pathogenesis spans key findings on the mechanisms of neurodegeneration and the role of specific genes that may lead to improved therapies for PD. The book reviews the major aspects of the disease including motoric and pathologic features, autonomic dysfunction, sleep disorders, and neuropsychiatric manifestations. It also provides an in-depth review of genetic considerations. With contributions by recognized experts on the topic, emphasis is placed on pathogenesis, experimental models, future therapeutic opportunities, and research trends affecting the field.

Jeffrey A. Cohen and Richard A. Rudick Cleveland Clinic Foundation, Ohio, USA

Since the publication of the previous edition of this volume, there has been substantial progress in a number of areas of multiple sclerosis (MS) research. Although immunosuppressive treatments continue to be developed and refined, more targeted immunomodulatory therapies are surfacing as we learn more about how the immune system works in health and disease. Multiple Sclerosis Therapeutics, Third Edition provides a comprehensive review of clinical trial methodology and therapeutic modalities in MS. This edition reflects current understanding of the pathophysiology of the disease and includes popular and emerging treatments.

Contents:

Topics include:

Overview. Neuropathology and Staging of Parkinson's Disease. Genetics of Parkinson's Disease. Epidemiology of Parkinson's Disease. Treatment of Parkinson's Disease. Genetics. Genetics of Alpha-Synuclein. Clinical and Genetic Features of PARKIN-Related Parkinson's Disease. DJ-1 in Parkinson's Disease. PINK1 Parkinsonism. LRRK2. Genetics of Tau in Parkinsonism. Genetic Risk Factors for PD. Pathogenesis. AlphaSynuclein and Parkinson's Disease. Tau in Parkinson's Disease. The Role of PARKIN in Parkinson's Disease. Mitochondrial Complex I Deficiency in Parkinson's Disease: A Mechanism for Oxidant-Based Pathogenesis. The Ubiquitin-Proteasome System in Parkinson's Disease. Animal Models. Transgenic Models of Alpha-Synucleinopathy. Mouse Models of Recessive Parkinsonism. Drosophila Models of Parkinson's Disease. Elegans Models of Parkinson's Disease. The MPTP Model of Parkinson's Disease. Rotenone Model. Drug Trials in Animal Models of PD

• Biomarkers in MS

Catalog no. DK5917, April 2007, 408 pp. ISBN: 978-0-8493-3697-3, $229.95 / £145.00 Also available as an eBook

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• Pharmacogenomics • Emerging therapeutic modalities such as natalizumab, T-cell-based and B-cell-based therapies, cytokine/chemokine-based therapies, statins, and 4-aminopyridine • Neuroprotection • The use of OCT and MRI to guide disease therapy Within the next several years, we will begin to discover the utility and the limitations of stem cells in the treatment of MS. It is likely that the next edition of this text will include clinical trial data that evaluate early attempts at nervous system regeneration in MS. Until that time occurs, this volume remains an essential resource for neurologists and anyone involved in the treatment of MS. Catalog no. DU5256, March 2007, 928 pp. ISBN: 978-1-84184-525-8, $289.95 / £180.00 Also available as an eBook

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Neurology Bestseller!

Sleep Disorders and Neurologic Diseases Second Edition Edited by

Antonio Culebras Upstate Medical University, Syracuse, New York, USA

Focusing on the relationship between sleep and brain function and the improved management of sleep in patients with neurologic diseases, Sleep Disorders and Neurologic Diseases, Second Edition offers recommendations for the management of primary sleep disorders, sleep disorders secondary to well-established neurological disorders, and the neurological consequences of uncontrolled sleep conditions.

Highlights include: • Wide-ranging coverage of the diagnosis, treatment, and management of these conditions • Insight into the effects of sleep disorders on both the healthy and diseased brain • The neurobiology of sleep and the development of sleep disorders • Sleep disorders associated with neurodegenerative diseases, restless legs syndrome, and circadian sleep disorders • Narcolepsy, sleep apnea, and movement disorders, as well as the findings of new epidemiological studies With chapters analyzing the treatment of specific disease states, this convenient guide also includes additional sections on the role of hypothalamic dysfunction in narcolepsy and the emerging relationship between sleep apnea and hypertension, heart disease, and stroke.

The Ischemic Penumbra Edited by

Geoffrey A. Donnan, Jean-Claude Baron, Stephen M. Davis, and Frank R. Sharp The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SPECT, MR, and CT for improved identification of key areas for intervention and therapy in the management of stroke patients. With chapters by international authorities on the topic—including the originator of the ischemic penumbra concept, Professor Lindsay Symon—this volume provides a comprehensive view of the ischemic penumbra ranging from neurochemical processes to clinical implications, imaging, and therapy. It contains the first authoritative discussion of the thresholds and duration of the ischemic penumbra documented in various species, with sections that outline cerebral blood flow levels and their effects on important biochemical parameters. The book also supplies an authoritative series of chapters individually focused on current imaging techniques to target the location and extent of the penumbra. It outlines the relevance of the ischemic penumbra to specific therapies, such as extending time windows for therapy, and studies the determination of the presence of penumbra using a novel imaging/clinical mismatch concept, with clinical evidence and validation to date.

Selected Contents:

Concept of Sleep Medicine and of Neurosomnology. Disorders of Development and Maturation of Sleep. Sleep Disorders Associated with Mental Retardation. Insomnia in Neurology. Delayed Sleep Phase Disorder and Other Circadian Rhythm Sleep Disorders. Narcolepsy. Secondary Narcolepsy. HypocretinHypothalamic System. Idiopathic Hypersomnia and Recurrent Hypersomnia. Motor Disorders of Sleep. Restless Legs Syndrome. Periodic Leg Movements of Sleep. Sleep In Parkinson's Disease. Epilepsy and Sleep. Somnambulism, Somniloquy, and Sleep Terrors. Rapid Eye Movement Sleep Behavior Disorder. ...

The Ischaemic Penumbra: An Overview. The Ischaemic Penumbra: The Beginning. The Ischaemic Penumbra: Overview, Definition, and Criteria. Perfusion Thresholds in Cerebral Ischaemia. Duration and Thresholds of the Ischemic Penumbra in Different Species. The Ischaemic Cascade: Events Within the Penumbra. Multimodal Mapping of the Ischaemic Penumbra in Animal Models. Molecular Biology of the Penumbra. Selective Neuronal Loss. Inflammation and Reperfusion Injury Within the Penumbra. Imaging the Penumbra: Other Approaches. Imaging the Penumbra with PET Flumazenil. Imaging the Penumbra: PET FMISO. Can the Penumbra be Imaged Using SPECT? Imaging the Penumbra with MR in Animals. Penumbra Imaged with MRI in Humans. ...

Catalog no. DK240X, February 2007, 456 pp. ISBN: 978-0-8493-4324-7, $199.95 / £125.00 Also available as an eBook

Catalog no. DK901X, April 2007, 344 pp. ISBN: 978-0-8493-3990-5, $199.95 / £125.00 Also available as an eBook

Selected Contents:

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Neurology Neural Tube Defects

Multi-Detector Computed Tomography in Cerebrovascular Disease

Edited by

Sonya G. Oppenheimer Cincinnati Children's Hospital Medical Center, Ohio, USA

CT Perfusion Imaging Edited by

Kenneth Miles Brighton & Sussex Medical School, Falmer, UK

James D. Eastwood Duke University Medical Center, Durham, North Carolina, USA

Matthias Konig Ruhr University Bochum, Germany

“The book has been written by some of the most knowledgeable people in the field of CT perfusion, and this applies to every chapter. Many of the authors are prolific in the cerebral CT perfusion literature. … well written and highly relevant.” —Clinical Radiology

Multidetector Computed Tomography in Cerebrovascular Disease: CT Perfusion Imaging focuses on anatomy and procedural strategy for perfusion CT imaging in clinical neurology and cerebrovascular disease. This text-atlas combines pictures and schematic diagrams to show how this new modality can be used to assess anatomy and guide therapeutic interventions. Beginning with an introductory section discussing the state of the art and background support (including software) related to the technique, the book then reviews applications in managing stroke, thrombosis and tumors. It concludes with a section that evaluates the utility of perfusion CT in comparison with other modalities such as MRI. A comprehensive introduction to further clinical applications of a newly established technology, this volume demonstrates the utility of the technique and covers all relevant theory necessary for its implementation.

Contents: Cerebral Perfusion Computed Tomography: An Historical Perspective. Scientific Basis and Validation. Implementing Deconvolution Analysis for Perfusion CT. Image Acquisition and Contrast Enhancement Protocols for Perfusion CT. Image Processing. Cerebrovascular Physiology and Pathophysiology. Diagnosis of Acute Stroke. Selection of Stroke Patients for Acute Treatment Using Perfusion-Computed Tomography (PCT) and Computed TomographyAngiography (CTA). Catalog no. DU3158, March 2007, 192 pp. ISBN: 978-1-84214-315-5, $109.95 / £70.00 Also available as an eBook

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Neural tube defects are one of the most complex birth defects and require an understanding of the interactions of multiple systems: the central nervous, urological, and musculoskeletal systems. Therefore, a truly multidisciplinary team of specialists is required to provide comprehensive treatment. Neural Tube Defects enables practitioners in all the relevant disciplines to gain understanding of how the pertinent elements of each system relevant to these afflictions relate to the other systems. The book focuses on quality-of-life issues and extensively surveys the medical, educational, social, and psychological needs of patients with neural tube defects. It studies best practices in the diagnosis, management, prevention, and screening of NTDs and details useful medical treatments and therapies that may reduce the impact of spina bifida on childhood and adolescent development. It also discusses psychological functioning in children and adolescents with spina bifida.

Contents: History of Spina Bifida; Sonya G. Oppenheimer The Global Epidemic of Folic Acid–Preventable Spina Bifida; Godfrey P. Oakley, Jr. Multidisciplinary Management Including Prenatal Care; Catherine M. Shaer School-Age Child: Academic Issues; James W. Loomis Psychological Functioning in Children and Adolescents with Spina Bifida; Robert T. Ammerman, Marsha J. Nortz, M. Douglas Ris, and Nicolay C. Walz Teenage Emphasis Achieving Independence; Donna Cheek Zahra

Adolescent Health-Care Transition; Thomas S. Webb and Tena Benson

Adults Who Have Spina Bifida: Work and Mental Health; Gregory S. Liptak Review of Current Neurosurgical Issues; Kerry R. Crone and Benjamin Ling New Orthopedic Trends; Junichi Tamai, Jose Herrera-Soto, and Alvin H. Crawford

New Urological Trends; Kazuyuki Nishinaka and Curtis A. Sheldon

Families that Have Children with Spina Bifida; Marlene L. Lutkenhoff

Ethical Issues; Linda S. Lazar Index Catalog no. DK5690, January 2007, 296 pp. ISBN: 978-1-57444-859-7, $179.95 / £115.00 Also available as an eBook

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Neurology/Pain Management Handbook of Acute Pain Management Edited by

Jennifer A. Elliott Shawnee, Kansas, USA

Howard S. Smith Delmar, New York, USA

Pain is a pervasive symptom present in multiple areas of medicine. It is imperative that physicians not only evaluate and diagnose the source of pain, but that they also recognize how to manage the actual pain symptoms with effective treatment. Handbook of Acute Pain Management is an essential reference for professionals to enhance their knowledge of pain therapies. Covering both pharmacologic and non-pharmacologic approaches to treatment, this text provides updates on the most recent developments in the management of pain. This includes information on potential drugdrug and drug-disease interactions, patient controlled analgesia devices, and the emergence of continuous catheter techniques. The text also addresses pain management issues in special populations such as pediatric, opioid tolerant, and elderly patients.

Contents: The Anatomy of Postoperative Pain. The Neurobiology of Acute Pain. Local Anesthetics in the Management of Acute Postoperative Pain. NSAIDS in the Management of Acute Pain. Opioids in the Management of Acute Pain. Patient Controlled Analgesia in the Management of Acute Pain. Authorised Agent Controlled Analgesia. Alpha2 Agonists in the Management of Acute Pain. Non Pharmacologic Modalities for the Acute of Acute Pain. Perioperative Epidural Analgesia and Patient Controlled Epidural Analgesia. Upper Extremity Regional Anaesthetic Techniques in the Management of Post Operative Pain. Lower Extremity Anesthetic Techniques in the Management of Postoperative Pain. Continuous Peripheral Nerve Catheter Techniques. Anticoagulation Guidelines in the Regional and Neuraxial Anesthesia. Pediatric Acute Pain - Diagnosis and Treatment. Pain Management in the Trauma Patient. Pain in the Obstretic Patient. Perioperative Care of the Opioid Tolerant Patient. Pain Management in the Elderly Postoperative Patient Catalog no. HW15514, December 2010 300 pp., Soft Cover ISBN: 978-0-7890-3168-6, $79.95 / £50.00 Also available as an eBook

Fibromyalgia Edited by

Bill McCarberg Kaiser Permanente, Escondido, California, USA

Daniel Clauw University of Michigan, Ann Arbor, USA

Utilizing evidence-based research, this revolutionary source explores the difficult diagnosis and management of the controversial syndrome of fibromyalgia. Carefully guiding physicians through the steps leading to diagnosis, Fibromyalgia emphasizes targeting the underlying fibromyalgia syndrome rather than treating each of its symptoms individually.

Written by recognized experts, the book: • Describes how to diagnose fibromyalgia • Advises how to handle patient distress • Recommends when to refer a patient to a specialist • Discusses how to motivate behavior changes in patients • Explores both traditional and up-and-coming pharmaceutical and non-pharmaceutical treatment methods

Contents: Etiology of Fibromyalgia; Daniel J. Clauw Evaluation; Leslie J. Crofford Nonpharmacological, Complementary and Alternative Treatments for Fibromyalgia; Robert Alan Bonakdar The Pharmacological Treatment of Fibromyalgia; Lesley M. Arnold

Psychosocial Issues in Fibromyalgia; Dennis C. Turk and Hilary D. Wilson

Disability Management in Patients with Fibromyalgia Syndrome; Raymond C. Tait and Vikrum Figoora Exercise as an Intervention for Individuals with Fibromyalgia; S. E. Gowans and A. deHueck Motivating Behavioral Change in Fibromyalgia; David A. Williams and Marissa L. Marshak

Fibromyalgia Management for the Primary Care Provider; Bill H. McCarberg Index Catalog no. H8679, June 2009, 213 pp. ISBN: 978-1-4200-8679-9, $119.95 / £75.00 Also available as an eBook

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Neurology/Pain Management Clinician’s Guide to Chronic Headache and Facial Pain Edited by

Gary W. Jay As headache and facial pain are two of the most common medical complaints, it is essential that practitioners are well equipped to handle these issues. This volume is designed for all clinicians dealing with these syndromes in daily practice—whether in the outpatient, emergency, or ambulatory setting. Presenting evidence-based chapters derived from past successes and failures, the book reviews both traditional and alternative interdisciplinary and interventional pain management therapies. The authors also discuss opioid usage and legal aspects of treatment to help prepare practitioners for a range of possible scenarios. Catalog no. H100108, November 2009, 336 pp. ISBN: 978-1-4398-2487-0, $159.95 / £100.00 Also available as an eBook

Practical Guide to Chronic Pain Syndromes Edited by

Gary W. Jay Clinically oriented and evidence-based, this volume supplies pain specialists, neurologists, and anesthesiologists with the latest critical advances in pain management. Key features include sections clearly organized by specific pain syndromes, chapters with basic structural templates for fast referencing, and two supplemental sections offering in-depth discussions of medications and other treatment options. Delivering a swift and accurate diagnosis aide, the book include recommendations for an array of syndromes, including headache/facial pain and soft-tissue, neuropathic, rheumatological, abdominal, urological, low back, and cancer-related pain. Catalog no. H8045, November 2009, 436 pp. ISBN: 978-1-4200-8045-2, $159.95 / £100.00 Also available as an eBook

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Guide to Chronic Pain Syndromes, Headache, and Facial Pain Catalog no. H100109, November 2009, 772 pp. ISBN: 978-1-4398-2501-3, $279.95 / £175.00

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Bestseller!

Chronic Pain Management Guidelines for Multidisciplinary Program Development Edited by

Michael E. Schatman Pain and Addiction Study Foundation, Bellevue, Washington, USA

Alexandra Campbell American Academy of Pain Management, Sonora, California, USA

“A useful review of the literature on multidisciplinary pain management, especially as it compares to traditional medical treatment.” — Christopher J. Graver, Ph.D., Western State Hospital in Doody’s Review

Chronic Pain Management: Guidelines for Multidisciplinary Program Development is the most comprehensive textbook to date on the multidisciplinary approach to chronic pain management. Written by an illustrious group of contributors, this volume serves as a must-have armamentarium of guidelines for the development of a successful pain management program within the context of current medical and insurance reimbursement climates. Backed by the American Academy of Pain Management, the book enables readers to understand the benefits of multidisciplinary chronic pain management and helps them apply these techniques to their clinic for effective, consistent, and financially viable patient care.

An essential how-to manual for anyone in the field, the book: • Emphasizes multidisciplinary chronic pain management as an alternative to surgery, chronic opioid therapy, and interventional approaches • Contains best practices for the maintenance of a high-quality cost-effective chronic pain management center • Discusses suggestions to enhance cooperation between the numerous groups involved in the care of chronic pain patients • Offers strategies for clinician-insurer collaboration resulting in clinically effective, cost-efficient treatment • Describes how to achieve accreditation, and how to develop policies and procedures • Helps insurance industry and government agencies recognize the importance of a multidisciplinary approach to pain management Catalog no. H4512, July 2007, 298 pp. ISBN: 978-1-4200-4512-3, $79.95 / £50.00 Also available as an eBook

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Neuroscience New!

The Textbook of Nanoneuroscience and Nanoneurosurgery Edited by

Babak Kateb Cedars Sinai Medical Center, West Hollywood, California, USA

John D. Heiss National Institutes of Health, Bethesda, Maryland, USA

Nanoneuroscience, nanoneurosurgery, and nanobioelectronics have the potential to revolutionize medicine and improve the prevention, diagnosis, and treatment of neurological disorders over the next 1020 years. The Textbook of Nanoneuroscience and Nanoneurosurgery presents a state-of-the-art review of the field, providing current information about nanoplatforms and their use in neurosurgery, neurology, neuroscience, and neuroradiology. The text also reviews the latest regulatory guidelines that influence the translation of nanotechnological research from the laboratory to the clinic, as well as the most recent information on biodevices and pharmaceutical spinoffs. It highlights presidential and congressional initiatives and programs that may significantly impact the field in the near future. Chapters discuss the latest science and technologies—which are applied to diagnosis and treatment of neurological disorders—as well as regulatory issues that impact product development. This volume describes advances that have already been translated to the clinic or hold significant promise for future application in nanoneurosurgery, as well as their potential impact. A full-color text, the book contains contributions by more than 120 researchers, original and descriptive illustrations, and more than 3,000 references. Offering broad coverage of nanotechnological applications in diverse areas and addressing FDA regulation and healthcare policy, this volume provides a foundation of ideas and methods for scientists and physicians to devise successful, less invasive procedures for future treatment of nervous system disorders.

Selected Contents: From Nanotechnology to Nanoneuroscience/Nanoneurosurgery and Nanobioelectronics: A Historical Review of Milestones. Nanoneurology and Nanoneurosurgery. Nanopolymers and Nanoconjugates for Central Nervous System Diagnostics and Therapies. Micelles and Liposomes: Lipid Nanovehicles for Intracerebral Drug Delivery. ... Catalog no. K12237, August 2013, 602 pp. ISBN: 978-1-4398-4941-5, $299.95 / £191.00 Also available as an eBook

Parkinson's Disease Second Edition Edited by

Ronald F. Pfeiffer University of Tennessee Health Science Center, Memphis, USA

Zbigniew K. Wszolek Mayo Clinic, Jacksonville, Florida, USA

Manuchair Ebadi University of North Dakota, Grand Forks, USA

Praise for the First Edition: “…an invaluable reference outlining our current understanding of this disease. … contains all the information that any student new to the field requires to develop a thorough understanding of PD. With chapters about everything from epidemiology, to theories of pathogenesis, and back to symptoms and treatment, this book covers the entire range of what we can know about a biological phenomenon, from the molecular, cellular and genetic levels, through to the whole human being and the entire human population. … accessible to both seasoned veterans of Parkinson’s research, looking for the last information in an area outside their direct expertise, and novices, trying to grasp an understanding of the extent of our current knowledge of PD.” —Elissa M. Strome, Department of Experimental Medical Science, Lund University, Sweden, in the Journal of Chemical Neuroanatomy

”I would recommend it highly to those with a specialist’s interest in Parkinson’s disease and to more general neurologists who want an accessible, readable guide to diagnosing and treating this disease.” —New England Journal of Medicine

In recent years, considerable advances have been made in our knowledge and understanding of Parkinson's disease (PD). In particular, there has been an explosion of information regarding genetic contributions to the etiology of PD and an increased awareness of the incidence and importance of the nonmotor features of the disease. Theories regarding the pathogenesis and pathophysiology of PD have also been refined, and new treatment modalities and advances have been implemented. Reflecting these changes, Parkinson’s Disease, Second Edition features new chapters devoted to genetic aspects of PD, non-motor features of the disease, and aspects of the pathophysiology, pathogenesis, and treatment of PD. Catalog no. K10361, October 2012, 1308 pp. ISBN: 978-1-4398-0714-9, $249.95 / £159.00 Also available as an eBook

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Neuroscience Maldynia Multidisciplinary Perspectives on the Illness of Chronic Pain Edited by

James Giordano Center for Neurotechnology Studies, Potomac Institute for Policy Studies, Arlington, Virginia, USA and Human Science Center, Ludwig-Maximilians University, Munich, Germany

Whether initiated by injury or disease, induced and sustained by changes in the nervous system, or manifested by society and culture, chronic pain can change one’s first-person experience of the body and the world, and ultimately impacts cognitions, emotions, and behavior. Many fine medical books address the causes and management of chronic intractable pain, but rarely do they focus on the ways that such pain creates illness and is experienced and expressed by persons in pain. Maldynia: Multidisciplinary Perspectives on the Illness of Chronic Pain is about chronic pain that has progressed to a multidimensional illness state in and of itself. Although often dismissed as such, this pain is not imaginary, but rather represents an interaction of neurobiological processes, emotional and behavioral responses, and socio-cultural effects and reactions that become enduring elements in the life and world of the pain patient, and often remain enigmatic for those who provide care. Taking a comprehensive approach that covers science, humanities, and culture, this volume emphasizes the need for researchers, clinicians, and caregivers to regard the ways in which chronic intractable pain becomes illness and affects a patient’s biological, social, and psychological states, as well as his or her sense of self. Edited by neuroscientist and neuroethicist James Giordano, the book contains 17 insightful chapters representing medicine, neuroscience, psychology, philosophy, ethics, history, art, and the ministry. This exceptional volume also looks at representations of pain in and through the arts, addresses the assignation of values and meaning in pain assessment and treatment, and considers ways to conjoin the sciences and humanities so as to inform the practice of pain medicine and improve the care of those suffering the illness of chronic pain.

Selected Contents: Maldynia: The Illness of Chronic Pain. A Short History of Pain and Its Treatment. Pain Does Not Suffer Misprision: The Presence and Absence that is Pain. Understanding Suffering: The Phenomenology and Neurobiology of the Experience of Illness and of Pain. Catalog no. K11642, December 2010, 280 pp. ISBN: 978-1-4398-3630-9, $167.95 / £107.00 Also available as an eBook

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Concussive Brain Trauma Neurobehavioral Impairment & Maladaptation, Second Edition Rolland S. Parker New York University School of Medicine, New York, USA

Focusing on a public health problem affecting millions of people of all ages, the second edition of Concussive Brain Trauma: Neurobehavioral Impairment and Maladaptation reflects Dr. Rolland S. Parker's more than 25 years of neuropsychological practice and research in traumatic brain injury and stress, and his prior experience as a clinical psychologist. Unique in its coverage of the personality changes, family dysfunction, and stress that often occur in the wake of concussive brain trauma, this book uses case examples to illustrate persistent and acute alterations of consciousness, as well as cognitive, mood, personality, and social effects of head injury in order to guide appropriate treatment. With six additional chapters, this edition covers: • Post-concussive syndrome, biomechanical causes of trauma, and acute and chronic phases of comorbid brain and somatic injury • The physiological basis for behavior and posttraumatic dysregulation of systems • Disorders related to pain, sensation, and motor activities • Headaches, consciousness, cognition, cerebral personality, and psychodynamic disorders • Developmental effects of children's concussive injury • Blast injuries characteristic of modern war • Unfamiliar signs not included in the usual list of post-concussive symptoms With a firm multi-disciplinary foundation, this book aids the concerned practitioner in rendering a more complete and accurate assessment, recognizing gaps in prior documentation, and conducting a more complete examination to acquire omitted information. It also shows how to achieve the benefit of higher accuracy in assessing disability, planning rehabilitation, and offering compensation. The book stands alone as an in-depth, authoritative guide to closed head injury and traumatic brain injury. Catalog no. 8039, September 2011, 879 pp. ISBN: 978-0-8493-8039-6, $167.95 / £107.00 Also available as an eBook

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Neuropsychology New!

Bestseller!

What You Think ADD/ADHD Is, It Isn't

Neuropsychology for Psychologists, Health Care Professionals, and Attorneys

Symptoms and Neuropsychological Testing Through Time Edited by

Barbara C. Fisher United Psychological Services, Shelby Township, Michigan, USA

ADD/ADHD is not as easily diagnosed or clear-cut as many believe; in fact it very often acts as a masking agent for other underlying, contributing disorders. It’s important that we understand ADD/ADHD better. What You Think ADD/ADHD Is, It Isn’t: Symptoms and Neuropsychological Testing Through Time is the culmination of the author’s years of research involving clinical experience and testing, resulting in the first all-encompassing examination of the ADD/ADHD disorder. Debunking common myths and shedding light upon the way this disorder truly impacts people, this volume: • Presents the results of the largest clinical research study for ADD/ADHD, compiling 20 years of testing • Distinguishes the inattentive form of ADD from ADHD and additional disorders using neuropsychological testing • Provides statistical analysis from neuropsychological evaluations and self-reporting questionnaires from parents, teachers, adolescents, and adults • Demonstrates how anxiety frequently masks itself as hyperactivity and increases through the lifespan • Addresses the issue of ADHD misdiagnosis • Explains the importance of diagnosing additional comorbid disorders that impact medication management and treatment

Third Edition Robert J. Sbordone, Ronald E. Saul, and Arnold D. Purisch This third edition remains an unparalleled reference on the assessment of patients by non-neuropsychologists. The book discusses current findings on age-related cognitive changes, PTSD, late onset dementia, and Alzheimer's, and includes a chapter on malingering and deception. It covers the latest diagnostic procedures and evaluates a wide range of neuropsychological tests in terms of their strengths, limitations, validity, and reliability as well as methods of scoring and interpretation. The book presents several case studies and sample reports, a glossary, a list of medications, and a quick-reference summary of the tests detailed in the text. Catalog no. 7309, June 2007, 544 pp. ISBN: 978-0-8493-7309-1, $164.95 / £105.00 Also available as an eBook

The Forensic Evaluation of Traumatic Brain Injury A Handbook for Clinicians and Attorneys, Second Edition Edited by

Gregory J. Murrey and Donald Starzinski

Common Definition of ADD/ADHD as We Know It Today: DSM-IV-TR. Description of the Population. Description of Tests Administered. Child Neuropsychological Testing for ADD/ADHD. Adolescent Neuropsychological Testing for ADD/ADHD.

A concise, general overview of the forensic assessment process, this book explores the issues surrounding traumatic brain injury. It identifies key topics involved in forensic assessment, including definitions and select medical diagnostic terminology and reviews the neurologic, neuropsychiatric, neuropsychological, and psychological assessment processes specific to brain injury cases. New chapters include neuropsychiatric evaluation, the qualifications and credibility of the forensic expert and the admissibility of expert testimony, the most recent court rulings, and neuropsychological rehabilitation issues. The book also contains outlines, tables, summaries, and forms useful in the forensic assessment process.

Catalog no. K11848, May 2013, 505 pp. ISBN: 978-1-4398-3996-6, $49.95 / £31.00 Also available as an eBook

Catalog no. 9075, November 2007, 200 pp. ISBN: 978-0-8493-9075-3, $159.95 / £107.00 Also available as an eBook

• Offers statistics showing the manner in which ADHD symptoms and additional issues affect people differently through the lifespan

Selected Contents:

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29


Psychiatry/Psychology Forthcoming!

Bestseller!

Dizziness and Vertigo

Textbook of Clinical Neuropsychiatry and Behavioral Neuroscience

An Introduction and Practical Guide Edited by

Rahul Kanegaonkar Medway Maritime Hospital, Kent, UK, and Guy's Hospital, London, UK

James Tysome Addenbrooke’s Hospital, Cambridge, UK

Vertigo and Dizziness: An Introduction and Practical Guide describes the basic knowledge and practical skills necessary for managing patients presenting with the common symptoms of dizziness and vertigo. It provides practitioners with a comprehensive overview of these conditions, steps for diagnosing patients, and various treatment options.

Features: • Discusses clinical assessment of the dizzy patient, diagnosis and management of the condition, surgical options, and psychological complications of vertigo and dizziness • Explores a host of conditions, including benign paroxysmal positional vertigo, Meniere's disease, hyperventilation syndrome, and superior semicircular canal dehiscence • Includes case studies to supplement the text The book is an essential reference for all those who manage patients in the outpatient and general practice setting.

Contents: Anatomy and Physiology of the Peripheral Vestibular System Clinical Assessment Vertigo Imaging in Dizziness and Vertigo Special Investigations Used in the Assessment of the Dizzy Patient Differential Diagnosis Benign Paroxysmal Positional Vertigo Acute Peripheral Vestibular Loss Vestibular Migraine Multilevel Vestibulopathy Cholesteatoma Meniere's Disease Superior Semicircular Canal Dehiscence Vestibular Schwannoma Perilymph Fistula Central Pathology Causing Dizziness Systemic Conditions Affecting Balance Vestibular Rehabilitation – Principles and Practice Catalog no. K17350, November 2013 176 pp., Soft Cover ISBN: 978-1-4441-8268-2, $55.95 / £34.99

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Third Edition David P. Moore and Basant K. Puri Previously published as Textbook of Clinical Neuropsychiatry, this highly acclaimed text provides a definitive, clinically oriented, yet comprehensive book covering neuropsychiatry and neuroscience for registrars, residents, clinicians, and practitioners of neuropsychiatry and its related fields. The book has been thoroughly updated, redesigned, and enhanced to include the fundamentals of neuroscience. Additions to the clinical coverage include chronic fatigue conditions, personality disorders, dissociative disorders, and impulse control disorders. Also included is access to a free eBook containing all the text and a wealth of supplementary material available online or from the reader’s desktop. Catalog no. K18326, June 2012, 864 pp. Pack - Book and Online ISBN: 978-1-4441-2134-6, $249.95 / £170.00 Also available as an eBook

Bestseller!

Traumatic Brain Injury Rehabilitation, Treatment, and Case Management, Third Edition Edited by

Mark J. Ashley Centre for Neuro Skills of California, Bakersfield, USA

The third edition of this highly respected text explores key information and recent advances in therapeutic approaches to traumatic brain injury. Designed for the new and experienced clinician, it offers pharmacological, anatomical, and physiological information for basic therapeutic rationales that are often misunderstood. This expanded edition includes details on metabolic and bioenergetic factors in brain injury, neuroendocrine dysfunction following brain injury, blast injury, ethical issues in treatment of brain injury, interventions for the minimally conscious patient, neuropharmacological and neuropsychological interventions following brain injury, and dietary and exercise considerations. Catalog no. 71947, May 2010, 1079 pp. ISBN: 978-1-4200-7194-8, $179.95 / £115.00 Also available as an eBook

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Psychiatry/Psychology Bestseller!

Schizophrenia Biopsychosocial Approaches and Current Challenges, Second Edition Edited by

Siegfried Kasper and George N. Papadimitriou Edited by the current president of the World Federation of Societies of Biological Psychiatry, and featuring an international list of world-renown contributors, this volume provides psychiatrists, neurologists, and psychologists with a comprehensive handbook on the latest schizophrenia research. It covers treatment options for management of the disease, including treatment of the first schizophrenic episode, pharmacogenetic approaches, comparative efficacy of older vs. new antipsychotic medication, as well as the management of side effects, psychosocial and cognitive rehabilitation, psychotherapy, and rehabilitation strategies. The book includes detailed coverage of interviewing, symptomatology evaluation, and cognitive assessment strategies to ensure accurate differential diagnosis. Catalog no. H8004, September 2009, 400 pp. ISBN: 978-1-4200-8004-9, $199.95 / £125.00 Also available as an eBook

Depression and Mood Disorders in Later Life

Handbook of Sleep Disorders Second Edition Edited by

Clete A. Kushida Stanford University, California, USA

Now in its second edition, this volume is the classic all-inclusive reference for sleep professionals around the world. Contributed by leading authorities, the new edition continues to provide a well-organized guide to the diagnosis and treatment of the major categories of sleep disorders—including insomnia, circadian rhythm disorders, narcolepsy, and parasomnias. Supported by tables and figures throughout, each disorder is covered in depth to help sleep professionals determine the key features of a specific disorder, distinguish each disorder from other sleep or medical disorders, and explore the range of treatments used in the management of each condition. Catalog no. DK7319, December 2008, 714 pp. ISBN: 978-0-8493-7319-0, $279.95 / £175.00 Also available as an eBook

Sleep Disorders

Second Edition

Diagnosis and Therapeutics

Edited by

Edited by

James E. Ellison, Helen H. Kyomen, Sumer Verma

S.R. Pandi-Perumal, Joris Verster, Jaime Monti, and Salomon Langer

McLean Hospital, Belmont, Massachusetts, USA

Examining the spectrum of mood disorders in older adults, this book focuses on major and nonmajor depressive disorders, bipolar disorder (manic and depressive phases), depression with psychotic features, and vascular depression. In-depth discussions of diagnosis and treatment options including psychotherapy, pharmacotherapy, ECT, and non-ECT neurotherapeutic approaches will help clinicians improve treatment outcomes in their elderly patients. The book addresses cross-cultural issues, the changing biochemistry and physiology of the aged, and the effect of pre-existing medical conditions and medications, as well as the importance of caution regarding drug interactions. Catalog no. H5329, December 2008, 368 pp. ISBN: 978-1-4200-5329-6, $159.95 / £100.00 Also available as an eBook

One of the first such volumes in this field, this book explores sleep pharmacology and therapeutics. Leading researchers in the area of experimental and clinical and psychopharmacology critically assess the progress in their specialist fields. The book is suitable as an introduction for clinicians and researchers who are new to sleep pharmacology and outlines the wider range of therapeutic options currently available to them. For seasoned clinicians, the book will assist in selecting the most appropriate methodologies and treatment options designed to circumvent the problems in combating sleep disorders. Catalog no. DU8187, July 2008, 770 pp. ISBN: 978-0-415-43818-6, $319.95 / £200.00 Also available as an eBook

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Psychiatry/Psychology Bestseller!

Antiepileptic Drugs to Treat Psychiatric Disorders Edited by

Asperger's Disorder Edited by

Jeffrey L. Rausch and Maria E. Johnson The Medical College of Georgia, Augusta, USA

Susan L. McElroy, Paul E. Keck, and Robert M. Post

Manuel F. Casanova

“The editors are well known and well regarded as are many of the authors who represent the handful of leaders in their respective areas. The overall topic is timely and is covered in greater depth than the usual journal supplements can provide.”

Today at least seven million children and adolescents are afflicted with Asperger’s disorder. Examining the etiology, diagnosis, and treatment of this condition, this volume provides the necessary guidance to psychiatrists and neurologists so they can correctly differentiate Asperger’s from other neurodevelopmental disorders. The book discusses brain morphology, chemistry, and function; related neuropathological findings; and screening instruments and imaging techniques. Also discussed are the genetics, epigenetics, and proteomics of Asperger's, relevant gene-environment interaction, social assimilation in the classroom, and biological treatment. Case studies enhance the text.

University of Louisville, Kentucky, USA

—Jonathan Alpert, M.D., Ph.D., Associate Director, Depression Clinical and Research Program, Massachusetts General Hospital, Boston

Several antiepileptic drugs (AEDs) now have regulatory indications for treating bipolar disorder. There is growing evidence that AEDs in general have a variety of useful psychotropic effects. Antiepileptic Drugs to Treat Psychiatric Disorders is the first comprehensive, clinically oriented reference on the use of AEDs to treat a variety of psychiatric conditions such as mood, psychotic, anxiety, substance use, eating, and personality disorders. Written by the leading clinical experts, the book is organized by psychiatric disorder for easier information gathering, enabling physicians to use the text as a standalone reference.

Contents: Mechanisms of Action of AEDs. AEDs in the Treatment of Epilepsy. AEDs in the Treatment of Neuropathic Pain. AEDs in the Treatment of Neuropsychiatric Symptoms Associated with Traumatic Brain Injury. AEDs in Intellectual Disability or Autism. Treatment of Acute Manic and Mixed Episodes. AEDs in Long-term Treatment of Bipolar Disorder. AEDs in the Treatment of Major Depressive Disorder. AEDs in the Treatment of Schizophrenia. AEDs in the Treatment of Anxiety Disorders. AEDs in the Treatment of Alcohol Withdrawal and Alcohol Use Relapse Prevention. AEDs in Drug Use Disorders. AEDs as Potential Aids to Smoking Cessation. AEDs in Obesity, Psychotropicassociated Weight Gain, and Eating Disorders. AEDs in the Treatment of Impulsivity and Aggression and Impulse Control and Cluster B Personality Disorders. AEDs and Borderline Personality Disorder. AEDs in the Treatment of Sleep Disorders. AEDS in Fibromyalgia. Psychotropic Mechanisms of Action of AEDs in Mood Disorder Catalog no. DK8259, June 2008, 440 pp. ISBN: 978-0-8493-8259-8, $159.95 / £97.00 Also available as an eBook

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Catalog no. DK8360, August 2008, 400 pp. ISBN: 978-0-8493-8360-1, $159.95 / £100.00 Also available as an eBook

Insulin Resistance Syndrome and Neuropsychiatric Disease Edited by

Natalie L. Rasgon Stanford University School of Medicine, California, USA

This is the first book of its kind to tie the metabolic syndrome with psychiatric disorders and raise the possibility that common antipsychotic treatments may have this type of adverse effect on patients. Presenting a complete overview on the relationship between insulin resistance syndrome and psychiatric and cognitive disorders, the book will be a welcome addition to the library of any psychiatrist, neurologist, endocrinologist, or research scientist. The book also discusses new treatments to help prevent metabolic complications among patients with neuropsychiatric illnesses, including schizophrenia, Alzheimer’s disease, and major depression. Catalog no. DK8208, April 2008, 168 pp. ISBN: 978-0-8493-8208-6, $119.95 / £75.00 Also available as an eBook

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Neurosurgery Comprehensive Management of Skull Base Tumors

Bestseller!

Edited by

Hans O. Luders

Ehab Y. Hanna and Franco DeMonte

The Cleveland Clinic Foundation, Ohio, USA

University of Texas, Houston, USA

The management of tumors in and adjacent to the skull base is challenging given the complex and critically important anatomy of the region and the wide diversity of tumor pathologies that may be encountered. To help navigate the complexities of contemporary multidisciplinary management of these patients, Comprehensive Management of Skull Base Tumors provides a comprehensive guide from worldwide authorities. The book consists of three sections encompassing general principles, sitespecific surgery, and tumor-specific management. Lavishly illustrated and enhanced with scientific tables, this text is written with an emphasis on surgery, radiation, and chemotherapy, and is an essential reference for neurosurgeons, otolaryngologists, plastic surgeons, maxillofacial surgeons, ophthalmologists, medical and radiation oncologists, and radiologists.

Selected Contents:

Textbook of Epilepsy Surgery Edited by

Textbook of Epilepsy Surgery covers all of the latest advances in the surgical management of epilepsy. The book provides a thorough understanding of epileptogenic mechanisms in etiologically different types of epilepsy and explains neuronavigation systems. It discusses new neuroimaging techniques, new surgical strategies, and more aggressive surgical approaches in cases with catastrophic epilepsies. The contributors also analyze the improved statistics of surgical outcome in different epilepsy types. The book follows a systematic approach to the diagnostic evaluation of patients who are candidates for epilepsy surgery. It first discusses the general principles of surgery, and then describes the presurgical evaluation according to the six zones (symptomatogenic, irritative, ictal onset, epileptic lesion, functional deficit, and epileptogenic zone). This series of chapters concludes with the description of the Epilepsy Surgery Management Meeting, an essential and indispensable part of the surgical evaluation.

General Principles. Anatomy of the Cranial Base. Pathology of Tumor and Tumor-like Lesions of the Skull Base. Genetic Abnormalities of Skull Base Tumors. Imaging of Skull Base Neoplasms. Head, Neck, and Neuro-otologic Assessment of Patients with Tumors of the Skull Base: Clinical. Examination, Auditory Testing, Vestibular Testing, and Equilibrium. Anesthesia and Intraoperative Monitoring of Patients with Tumors of the Skull Base. Minimally Invasive Techniques: Endonasal Endoscopic Skull Base Surgery. Reconstruction of Skull Base Defects. Prosthetic Rehabilitation of Patients Undergoing Skull Base Surgery. Radiobiology and Radiation Therapy of SkullBase Tumors. Chemotherapy for Skull Base Tumors. Rehabilitation of Speech and Swallowing of Patients with Tumors of the Skull Base. Quality of Life of Patients with Skull Base Tumors. Neurocognitive Assessment of Patients with Tumors of the Skull Base. Cerebrovascular Management in Skull Base Tumors. Site-Specific Considerations. Surgical Management of Tumors of the Nasal Cavity, Paranasal Sinuses, Orbit, and Anterior Skull Base. Tumors of the Nasopharynx. Clival Tumors. Tumors of the Anterior Skull Base. Infratemporal/Middle Fossa Tumors. Tumors of the Parapharyngeal Space. Tumors of the Temporal Bone. Evaluation and Management of Sellar Tumors. Tumors of the Middle Cranial Fossa. Tumors of the Petrous Apex. Tumors of the Cerebellopontine Angle.

The book next incorporates detailed discussions of the cortical mapping techniques and the numerous surgical techniques. This is followed by the post-surgical medical management and a discussion of the surgical outcome. Finally, selected case studies are presented, along with protocols for the storage and processing of brain tissue for molecular studies. This definitive textbook is an invaluable reference for neurologists, neurosurgeons, epilepsy specialists, and those interested in epilepsy and its surgical treatment.

Catalog no. DK054X, November 2008, 600 pp. ISBN: 978-0-8493-4054-3, $399.95 / ÂŁ250.00 Also available as an eBook

Catalog no. DU5760, July 2008, 1648 pp. ISBN: 978-1-84184-576-0, $550.00 / ÂŁ350.00 Also available as an eBook

Contents: History of Epilepsy Surgery and related fields. Overview. Epilepsies Remediable by Epilepsy Surgery. Presurgical Evaluation: General Principles. The Symptomatogenic Zone. The Irritative Zone. The Ictal Onset Zone. The Epileptic Lesion. The Functional Deficit Zone. Presurgical Evaluation of Eloquent Cortex. The Epileptogenic Zone. The Patient Management Meeting. Surgical Techniques for Placement of Intracranial Electrodes. Cortical Mapping and Electrocorticography. Resective Surgical Procedures for Epilepsy. Non-resective Surgical Procedures and Electrical or Magnetic Stimulation. Surgical Outcome. Post-surgical Management. Neuropathology and Research. Surgical Failures: Reoperation. Case Presentations. Appendices

For more information and complete contents, visit www.crcpress.com

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Neurosurgery Bestseller!

Minimally Invasive Spine Surgery Edited by

Alexander R. Vaccaro Rothman Institute Philadelphia, Pennsylvania, USA

Christopher M. Bono Boston University Medical Center, Massachusetts, USA

Minimally invasive procedures are increasingly utilized and are replacing open surgery to reduce scarring and pain, enhance patient recovery, and minimize cost. Minimally Invasive Spine Surgery provides step-bystep guidance, expert instruction, and detailed illustration of current minimally invasive orthopedic spine procedures. With a variety of chapters covering critical developments in the field—including the utilization of biologic materials, image-guided surgery, and bone fusion—this guide delves into discussions of indications, methods for preoperative planning, complication avoidance strategies, and patient outcomes. Covering emerging technologies and biological advances that will result in smaller incisions, less trauma, and enhanced patient rehabilitation, this book: • Helps surgeons identify key anatomical structures for minimally invasive access • Considers preoperative planning, complications, and outcomes for all operative methods • Updates surgeons on significant advances in bone graft substitutes for spine fusion • Details decompression and mini-open surgical techniques—all intended to achieve less traumatic surgical treatments and improve patient outcomes • Includes a section on needle-based procedures for chronic pain relief

Selected Contents: Introduction. Anatomical Approaches for Minimally Invasive Spine Surgery. Debate Forum: Evidence-Based Support for Minimally Invasive Spine Surgery Versus Open Surgery. Patient Selection Issues for Minimally Invasive Spine Surgery. Minimally Invasive Decompressive Procedures. Microscopic Anterior Cervical Discectomy, Foraminotomy and Uncinectomy. Endoscopic Laminotomy, Discectomy for Herniated Lumbar Disk. Unilateral HemiLaminectomy for Bilateral Lumbar Decompression. Chemical Dissolution of a Herniated Lumbar Disk. Minimally Invasive Techniques Of Instrumentation And Fusion. Odontoid Screw Insertion. Catalog no. DK029X, May 2007, 424 pp. ISBN: 978-0-8493-4029-1, $219.95 / £140.00 Also available as an eBook

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Spinal Reconstruction Clinical Examples of Applied Basic Science, Biomechanics and Engineering Edited by

Kai-Uwe Lewandrowski, Michael J. Yaszemski, Iain Kalfas, Paul Park, Robert F. McLain, and Debra J. Trantolo With an ever-expanding array of biomaterials and implant devices appearing in the field, Spinal Reconstruction: Clinical Examples of Applied Basic Science, Biomechanics and Engineering helps surgeons assess and utilize the latest technologies to improve the reconstruction of the spine and enhance the reconstitution of diseased spinal segments. With illustrative descriptions of specific clinical scenarios, this guide helps surgeons select the best devices and materials for reconstructive procedures and considers issues in biocompatibility, biostability, and structurefunction relationships for enhanced patient outcomes and mobility.

With more than 350 figures and photographs, this book: • Details current strategies in minimally invasive spine surgery as currently applied to the lumbar spine • Covers the myriad of patient factors, orthobiologic grafting alternatives, and technique-driven mechanical options encountered in spinal care and reconstruction • Identifies new surgical techniques for spinal fusion, vertebral compression fractures, and arthroplasty • Discusses the basic mechanisms and clinical application of currently available operative treatments • Supplies the most up-to-date information on the evaluation, diagnosis, and operative treatment of spinal pain, deformity, and disease

Selected Contents: The Role of Minimally Invasive Surgery in Instrumented Lumbar Fusions. Minimally Invasive Transforaminal Lumbar Interbody Fusion (MITLIF). Non-Endoscopic Percutaneous Disc Decompression as Treatment of Discogenic Radiculopathy. Clinical Strategies for Delivery of Osteoinductive Growth Factors. ... Catalog no. DK9815, February 2007, 480 pp. ISBN: 978-0-8493-9815-5, $239.95 / £150.00 Also available as an eBook

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