Table of Contents

3 | In This Issue

Omar A. Khan, M.D., M.H.S. Timothy E. Gibbs, M.P.H.

4 | Guest Editor

Louis E. Bartoshesky, M.D., M.P.H., F.A.C.M.G.

5 | Guest Editor

Eric B. Kmiec, Ph.D.

6 | Recent Scientific Breakthroughs Applying CRISPR Gene Editing in Neurological Disorders

Mitra Assadi-Khansari, M.D., F.A.A.N. London Pamela McGill, M.S.

10 | Impact of Genetic Testing on Human Health: The Current Landscape and Future for Personalized Medicine

Vicky L. Funanage, Ph.D.

12 | Realities of Pharmacogenomic and Minimizing Misconceptions and Medication Misadventures

Benjamin Duong, Pharm.D.

20 | The Genetic Testing Stewardship Program: A Bridge to Precision Diagnostics for the Non-genetics Medical Provider

Morgan Thomas, M.G.C., C.G.C. Louise Amlie-Wolf, M.S., C.G.C. Laura Baker, M.G.C., C.G.C. Karen W. Gripp, M.D., F.A.C.M.G.

24 | Molecular Genetic Testing for Kidney Disorders During the COVID-19 Pandemic

Susan M. Kirwin Katherine M. Robbins, Ph.D. Kathleen M.B. Vinette Lee Hirata Karen W. Gripp, M.D. Vicky L. Funanage, Ph.D.

32 | Development of Cell Lines for use in COVID-19 Drug Development and Research

London McGill, M.S.

36 | Accelerating the Pace of Newborn Screening Research to Advance Disease Understanding and Improve Health Outcomes: Key Efforts of the Newborn Screening Translational Research Network (NBSTRN)

Amy Brower, Ph.D. Kee Chan, Ph.D., M.P.H. Jennifer Taylor, Ph.D. Ross Wiebenga Galata Tona, M.S. Yekaterina Unnikumaran, M.S. LaStephanie Barnes

38 | Life Sciences at Delaware Technical Community College

Mark T. Brainard, Ph.D.

40 | Impact of the Access to Genetic Counselor Services Act

Carol Nowlen, M.S. Kendra Flores, M.S., C.G.C.

42 | CRISPR In A Box™ and the Journey Toward Inspiring New Scientists

Kristen Pisarcik

44 | An Examination of Seasonal Trends in Delaware Drug Overdoses, 2016-2020

Aswini Abraham, M.S. Andrew C. Gray, M.A. Jascha Wagner, Ph.D. Tammy L. Anderson, Ph.D.

52 | Global Health Matters Sept-Oct 2021

Fogarty International Center

64 | Disparities in Delaware Caregiver Beliefs about the COVID-19 Vaccine for their Children

Thao-Ly Tam Phan, M.D., M.P.H. Paul T. Enlow, Ph.D. Michael K. Wong Amanda M. Lewis, M.P.H. Anne E. Kazak, Ph.D., A.B.P.P. Jonathan M. Miller, M.D.

72 | Characteristics and Outcomes of SARS-CoV-2 Infection Among Adults Living With HIV In Delaware: The Story of a Syndemic During the First 12 Months of the SARS-CoV-2 Pandemic

Adam K Skrzynski, M.D. Brooke L Darmstadter, Pharm.D., A.A.H.I.V.P. Sharon P Miner, A.G.P.C.N.P.-B.C. Keshab Subedi, M.S., M.Sc. Deborah Kahal, M.D., M.P.H., F.A.C.P.

80 | Team Up For Quality Care: The Role of Primary Care Teams in Prevention Of Cardiovascular Disease

Cindy Biederman, M.S.N., R.N.

92 | History & Archives: Letter to the Editor

Sharon Folkenroth-Hess, M.A.

94 | Genetics Lexicon

96 | Genetics Resources

96 | Genetics More Information

97 | Index of Advertisers