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Datasheet of Acitazanolast
Description: Acitazanolast is an active metabolite of tazanolast and anti-allergic drug. In a study, pretreatment with topical instillation of acitazanolast hydrate inhibited the dye leakage significantly. In the histopathological observation, acitazanolast hydrate ophthalmic solution also improved the inflammatory score and reduced the infiltration of inflammatory cells such as neutrophil and eosinophil in conjunctiva markedly. These anti-allergic effects of acitazanolast hydrate ophthalmic solution were equal to those of levocabastine and ketotifen. From these results, it is suggested that acitazanolast hydrate ophthalmic solution is a promising ophthalmic solution For treatment of allergic conjunctivitis. For the detailed information about the solubility of Acitazanolast (WP-871, Zepelin) in water, the solubility of Acitazanolast (WP-871, Zepelin)in DMSO, the solubility of Acitazanolast (WP-871, Zepelin) in PBS buffer, the animal experiment（test） of Acitazanolast (WP-871, Zepelin),the in vivo,in vitro and clinical trial test of Acitazanolast (WP-871, Zepelin),the cell experiment（test） of Acitazanolast (WP-871, Zepelin),the IC50, EC50 and Affinity of Acitazanolast (WP-871, Zepelin), please contact DC Chemicals.
Chemical Information Catalog
DC1092
Purity of current batch:
>98%
Molecular Weight (MW)
233.186
Molecular Formula
C9H7N5O3
CAS No.
114607-46-4
Solubility (25°C)
DMSO
Storage
Store at -20°C (desiccating conditions).
Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.