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Datasheet of LY379268
Description: Highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM For hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors. Provides protection against NMDA-mediated cell death in vitro and offers almost complete protection against CA1 hippocampal damage following global ischemia in gerbils. Orally and systemically active. For the detailed information of LY379268, the solubility of LY379268 in water, the solubility of LY379268 in DMSO, the solubility of LY379268 in PBS buffer, the animal experiment (test) of LY379268, the cell expriment (test) of LY379268, the in vivo, in vitro and clinical trial test of LY379268, the EC50, IC50,and Affinity of LY379268, Please contact DC Chemicals.
Chemical Information Catalog
DC7148
Purity of current batch:
>98%
Molecular Weight (MW)
187.15
Molecular Formula
C7H9NO5
CAS No.
191471-52-0
Solubility (25째C)
DMSO
Storage
Store at -20째C (desiccating conditions).
Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20째C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.