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Datasheet of BMS-707035
Description: BMS-707035 is a pyrimidine carboxamide similar to Raltegravir. BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity. BMS-707035 binding and target DNA binding to IN are mutually exclusive events, as elucidated by the fact that increasing the amount of target DNA overcomes the inhibition of strand transfer catalysis by BMS-707035. BMS-707035 binding affinity to IN is also affected by the four terminal bases at the 5’ end of the pre-processed U5 long terminal repeat (LTR). \Chemical
Information
Catalog
DC9700
Purity of current batch:
>98%
Molecular Weight (MW)
410.42
Molecular Formula
C17H19FN4O5S
CAS No.
729607-74-3
Solubility (25°C)
DMSO
Storage
Store at -20°C (desiccating conditions).
Handling: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.